Enhanced Dedicated Channel (E-DCH) Transmissions Related to Tune-Away Occurrences

Various embodiments provide methods for a multi-Subscription Identity Module (SIM) wireless communication device for managing data exchanges with a network when an enhanced dedicated channel is requested on a first subscription. The methods may include performing operations during a testing phase to determine whether an enhanced dedicated channel grant is valid after a tune-away to a second subscription is completed, while transmitting data using the enhanced dedicated channel presuming that the enhanced dedicated channel grant is valid during the testing phase. The methods may include recording a list of protocol data units (PDUs) corresponding to data transmitted using the enhanced dedicated channel during the testing phase. The list of PDUs may be cleared and data exchanged with the network in response to determining that the enhanced dedicated channel grant is valid. Otherwise, the multi-SIM wireless communication device may request another enhanced dedicated channel grant.

AUTOMATIC GENERATION OF FLEXIBLE LOAD DESIGN

A system including one or more processors and one or more non-transitory computer-readable media storing computing instructions that, when executed on the one or more processors, perform certain acts. The acts can include obtaining an original load design for loading a trailer to deliver stacks of pallets to physical stores. The load design specifies a respective floor spot assignment for each of the stacks. The original load design satisfies center-of-gravity constraints. The acts also can include generating fluid groups of the stacks to form an initial fluid grouping. The acts additionally can include determining that the fluid groups do not collectively satisfy the center-of-gravity constraints. The acts further can include until the fluid groups collectively satisfy the center-of-gravity constraints, repeatedly determining one or more infeasible groups from the fluid groups, and adjusting at least one of the one or more infeasible groups to update the fluid groups. The acts additionally ...

Process for the manufacture of substituted 2-cyano cinnamic esters

The invention relates to an improved process for the manufacture of substitute 2-cyanocinnamic esters. This novel economical process provides products in high purity and yields.

LARGE SCALE PRODUCTION OF EXOSOME MIMETICS AND USES THEREOF

Provided herein are methods of producing exosome mimetics that are homogenous in size and are akin to native exosomes in structure and/or biological function. Also provided herein are the use of the EMs as delivery vehicles to deliver agents (e.g., therapeutic agents or diagnostic agents) for treating or diagnosing a disease.

Organic light-emitting diode device and display apparatus

Provided are an organic light-emitting diode device and a display apparatus. The organic light-emitting diode device comprises: a glass substrate, a first electrode, an organic light-emitting layer, a second electrode and an emergent-light enhancement layer which lies under the glass substrate or above the second electrode. The material of the emergent-light enhancement layer comprises a first material of a first refractive index and a second material of a second refractive index. The difference between the first refractive index and the second refractive index is greater than a pre-set threshold.

HOST CELLS AND METHODS USEFUL FOR PRODUCING UNNATURAL TERPENOIDS USING A NOVEL ARTIFICIAL METALLOENZYME

The present invention provides for a genetically modified host cell capable of producing an unnatural compound, such as terpenoid, comprising a P450 enzyme comprising an artificial cofactor, and the host cell is capable of uptaking the artificial cofactor by comprising a heterologous heme transport transmembrane protein, or homologue thereof.

Methods and compositions that utilize transciptome sequencing data in machine learning-based classification

Provided herein are methods and systems for producing a modified biological dataset by flagging or removing a nucleic acid sequence from the biological dataset that is assigned a noise-call to produce the modified biological dataset. The noise-call may be based on comparing a gene expression level, sequence information, or a combination thereof with a nucleic acid sequence of a control sample.

METHOD AND SYSTEM FOR ASPECT-LEVEL SENTIMENT CLASSIFICATION BY GRAPH DIFFUSION TRANSFORMER

System and method for aspect-level sentiment classification. The system includes a computing device, the computing device has a processer and a storage device storing computer executable code. The computer executable code is configured to: receive a sentence having a labeled aspect term and context; convert the sentence into a dependency tree graph; calculate an attention matrix of the dependency tree graph based on one-hop attention between any two nodes of the graph; calculate multi-head attention diffusion for any two nodes from the attention matrix; obtain updated embedding of the graph using the multi-head diffusion attention; classify the aspect term based on the updated embedding of the graph to obtain predicted classification of the aspect term; calculate loss function based on the predicted classification and the ground truth label of the aspect term; and adjust parameters of models in the computer executable code based on the loss function.

END-TO-END STRUCTURE-AWARE CONVOLUTIONAL NETWORKS FOR KNOWLEDGE BASE COMPLETION

A method for knowledge base completion includes encoding a knowledge base comprising entities and relations between the entities into embeddings for the entities and embeddings for the relations. The embeddings for the entities are encoded based on a Graph Convolutional Network (GCN) with different weights for at least some different types of the relations, which GCN is called a Weighted GCN (WGCN). The method further includes decoding the embeddings by a convolutional network for relation prediction. The convolutional network is configured to apply one dimensional (1D) convolutional filters on the embeddings, which convolutional network is called Conv-TransE. The method further includes at least partially complete the knowledge base based on the relation prediction.

Operation, administration and maintenance OAM data transmission method and apparatus

The present disclosure relates to operation, administration and maintenance (OAM) data transmission methods and apparatus. One example method includes obtaining a first data flow of a client, inserting an OAM data block in the first data flow of the client to obtain a second data flow of the client, where the OAM data block is a 64B/66B code block that carries OAM data, and distributing the second data flow of the client to at least one slot of a channel corresponding to the client.

Display panel, driving method, and display device with real time switch of forward and reverse scanning

A display panel, a driving method of a display panel, and a display device are provided. The display panel includes pixel circuits and a gate driving circuit including cascaded first shift register units. A trigger signal input terminal of the first stage first shift register unit is connected to a trigger signal terminal through a first switch element. A signal output terminal of the i-th stage first shift register unit is connected to a trigger signal input terminal of the (i+1)-th stage first shift register unit through a second switch element. A trigger signal input terminal of the N-th stage first shift register unit is connected to the trigger signal terminal through a third switch element. A signal output terminal of the j-th stage first shift register unit is connected to a trigger signal input terminal of the (j−1)-th stage first shift register unit through a fourth switch element.

IPv4 data center support for IPv4 and IPv6 visitors

A network element (NE) comprising a processor configured to transmit a message to a domain names system (DNS) server, wherein the message comprises a virtual service internet protocol (VSIP) version six (VSIPv6) address corresponding to a service associated with an internet protocol version four (IPv4) address. Also disclosed is a method comprising associating a remote host internet protocol (IP) version six (IPv6) address with a private IPv4 address in a stateful binding table, and associating a local service IPv4 address with a local service VSIPv6 address in a stateless binding table.

Stateless NAT44

An apparatus comprising a memory, and a processor coupled to the memory and configured to receive a mapping rule that associates a downstream internal Internet Protocol version four (IPv4) address prefix to an upstream external IPv4 address prefix, receive a first IPv4 packet from an upstream network node with a destination address field comprising an external IPv4 address comprising the external prefix, and perform a first network address translation IPv4 to IPv4 (NAT44) process by replacing the external IPv4 address in the first IPv4 packet's destination address field with an internal IPv4 address based on the mapping rule, wherein the internal IPv4 address comprises the internal prefix and a port set identifier (ID) associated with set of destination ports at a downstream node assigned to receive the first IPv4 packet.

Bit Block Stream Bit Error Detection Method and Device

A method includes: sending a first boundary bit block; sequentially sending an Ith bit block; determining a first parity check result and a second parity check result, where a check object of the first parity check result includes m consecutive bits of each bit block in the N bit blocks, a check object of the second parity check result includes n consecutive bits of each bit block in the N bit blocks, and at least one of m and n is greater than or equal to 2; and sending a second boundary bit block, the first parity check result, and the second parity check result.

Method, device, and system for forwarding packet

The embodiments of the present invention provide a method, a device, and a system for forwarding a packet. The method includes: receiving an IPv6 packet sent by a gateway, and obtaining a flow label of the IPv6 packet, where the flow label of the IPv6 packet is corresponding to a link identity of customer premise equipment in one-to-one correspondence; decapsulating the IPv6 packet; performing network address translation on a decapsulated packet according to the flow label; and forwarding the decapsulated packet according to a translated network address. When multiple links between the gateway and an AFTR are corresponding to the same tunnel for network address translation, in the case that IP addresses of terminal users are overlapping or are the same, different terminal users can be distinguished, so that a terminal user that sends a packet can receive feedback, thus improving customer satisfaction.

DISPLAY PANEL AND DISPLAY APPARATUS

A display panel and a display apparatus are provided. The display panel includes a substrate and an array layer at a side of the substrate. The array layer includes pixel circuits and at least one first via. The pixel circuit includes transistors. Each transistor includes an active layer. The active layer includes a channel. The transistor includes a driving transistor and a first switching transistor. In a direction perpendicular to the substrate, a distance between one of the at least one first via and the channel of the driving transistor closest to the first via is greater than a preset distance. A distance between an edge of the one of the at least one first via and an edge of the channel of the first switching transistor closest to the one of the at least one first via is smaller than the preset distance.

Methods and Compositions for Hair Growth by Activating Autophagy

Disclosed are methods improving or stimulating hair regeneration; treating, inhibiting, or reducing hair loss; improving or stimulating hair growth; treating, inhibiting, or reducing pigmentation loss; and/or improving or stimulating pigmentation production in a subject with one or more autophagy inducing agents.

Operation, administration and maintenance OAM data transmission method and apparatus

The present disclosure relates to operation, administration and maintenance (OAM) data transmission methods and apparatuses. One example method includes obtaining, by a first node, a first data flow of a client. The first node inserts an OAM data block in the first data flow of the client to obtain a second data flow of the client, where the OAM data block is a 64B/66B code block that carries OAM data. The first node distributes the second data flow of the client to at least one slot of a channel corresponding to the client.

Ketobutyrate Compounds and Compositions for Treating Age-Related Symptoms and Diseases

Disclosed herein are methods for (a) treating, inhibiting, or reducing aging of a subject, (b) treating, inhibiting, or reducing an age-related symptom or an age-related disease in a subject, and/or (c) increasing the lifespan of a subject which comprise administering to the subject one or more ketobutyrate compounds and compositions thereof.

Methods and systems for detecting usual interstitial pneumonia

The present disclosure provides systems, methods, and classifiers for differentiating between samples as usual interstitial pneumonia (UIP) or non-UIP.

Validation of routes in automatic route design

A system including one or more processors and one or more non-transitory computer-readable media storing computing instructions configured to run on the one or more processors and perform certain acts. The acts can include obtaining a sequence of stops and service time windows for the stops. The acts also can include generating a sequence of driver states that satisfies the sequence of the stops. The acts further can include determining, for each pair of respective sequential driver states from the sequence of driver states, whether to generate a respective recommendation to add a respective additional driver state within the respective sequential driver states in order to satisfy a set of rules. The acts additionally can include updating the sequence of driver states based on the respective recommendations, such that the sequence of driver states is feasible in view of the service time windows and the set of rules. The acts further can include outputting the sequence of driver states.

Table

Water dispenser system

An apparatus is disclosed for dispensing water including: a main inlet configured to receive water from a source; a chilled water line, including: an in-line carbonator; a carbonator water inlet valve configured to selectively direct water from the main inlet to the carbonator; a carbonator gas inlet valve configured to selectively direct carbonating gas to the carbonator; and a chilled water line outlet. The apparatus may be integrated in a refrigerator or other major appliance.

Methods for Identifying DNA Copy Number Changes

Methods of identifying allele-specific changes in genomic DNA copy number are disclosed. Methods for identifying homozygous deletions and genetic amplifications are disclosed. An array of probes designed to detect presence or absence of a plurality of different sequences is also disclosed. The probes are designed to hybridize to sequences that are predicted to be present in a reduced complexity sample. The methods may be used to detect copy number changes in cancerous tissue compared to normal tissue. The methods may be used to diagnose cancer and other diseases associated with chromosomal anomalies.

Camera Control Method, User Equipment, and Camera

A camera control method, user equipment (UE), and a camera where the camera control method includes sending a detection request message to an Internet Protocol (IP) multimedia subsystem (IMS), where the detection request message includes a detection instruction, where the detection instruction is used to instruct, after the IMS forwards the detection request message to the camera, the camera to send a detection response message carrying device information to the UE using the IMS according to the detection instruction, receiving the detection response message returned by the IMS, and displaying corresponding parameter information and function keys according to the device information of the camera included in the detection response message.

Methods for high throughput genotyping

Methods for genotyping polymorphisms using allele specific probes are disclosed. A training set is used to generate a model for each polymorphism to be interrogated. The training set is used to obtain an estimate of the asymmetry between an intensity measurement for a first allele and an intensity measurement for a second allele of the same polymorphism. The intensity measurement obtained for a test sample is adjusted using the estimate of asymmetry prior to using the intensity measurements to make a genotyping call. In preferred embodiments the adjustment is applied to polymorphisms that have a likelihood of being heterozygous that is above a specified threshold.

Flexible OLED panel, thin-film encapsulation structure of flexible panel and encapsulation method for the same

The present invention relates to a flexible OLED panel, thin-film encapsulation structure of flexible panel and encapsulation method for the same. The present invention includes a first inorganic layer, a first organic layer and a second inorganic layer structure, wherein the first organic layer is prepared by using hexamethyldisiloxane which is an organic material to form the first retaining wall. The hydrophilicity/hydrophobicity between the first retaining wall and the first organic layer is oppositely disposed such that the surface of the first retaining wall and the first organic layer do not mutually dissolve when contacted. The feature can greatly reduce the thickness of the at least one retaining wall. While ensuring that the flexible panel display region is shielded from external water oxygen, covering the particle contaminant of the flexible panel, buffering the stress during bending and folding, and the present invention has more simplified and more reliable features.

Methods for nucleic acid sequencing

The present invention provides methods for sequencing and analysis of nucleic acids and determining that a subject is positive for a non-usual interstitial pneumonia subtype.

Process for the manufacture of substituted 2-cyano cinnamic esters

The invention relates to an improved process for the manufacture of substituted 2-cyanocinnamic esters. This novel economical process provides products in high purity and yields.

Thin-film encapsulation structure of flexible panel having opposite hydrophilic/hydrophobic arrangement

The present invention relates to a flexible OLED panel, thin-film encapsulation structure of flexible panel and encapsulation method for the same. The present invention includes a first inorganic layer, a first organic layer and a second inorganic layer structure, wherein the first organic layer is prepared by using hexamethyldisiloxane which is an organic material to form the first retaining wall. The hydrophilicity/hydrophobicity between the first retaining wall and the first organic layer is oppositely disposed such that the surface of the first retaining wall and the first organic layer do not mutually dissolve when contacted. The feature can greatly reduce the thickness of the at least one retaining wall. While ensuring that the flexible panel display region is shielded from external water oxygen, covering the particle contaminant of the flexible panel, buffering the stress during bending and folding, and the present invention has more simplified and more reliable features.

Method and system for mouse pointer to automatically follow cursor

Embodiments of the present application disclose a method for controlling a mouse pointer to automatically follow a cursor. During operation, the system detects whether the cursor is in a currently active window displayed on a screen of a computing device. In response to detecting that the cursor is in the currently active window, the system obtains coordinates of the cursor. The system then calculates follow coordinates according to the coordinates of the cursor and a predetermined distance value. The system subsequently sets coordinates of the mouse pointer to the follow coordinates.

Multi-Hop Wireless Network Plannning

In one embodiment, a method includes accessing a point cloud comprising a plurality of point-cloud points, each point-cloud point corresponding to a location on a surface of an object located in a region in a three-dimensional space, identifying, from the point cloud, a plurality of point clusters, each point cluster comprising a plurality of point-cloud points located within a grid segment on a two-dimensional grid derived from the three-dimensional space, selecting, for each point cluster, a set of point-cloud points from the plurality of point-cloud points in the point cluster, the set of point-cloud points being selected based on a predetermined threshold number of point-cloud points associated with an acceptable reduction in an error detection rate, and determining, for each point cluster, a structure classification based on the selected set of point-cloud points from the point cluster.

Universal bridge and wall mounted aeration apparatus

A universal wall and bridge mounted aeration apparatus has a track extending between two distinct elevations that is coupled to a wall and bridge mount. An aeration unit is pivotally coupled to the track and has an aerator adapted to operatively at least partially submerge within and aerate a liquid. A selective mover or drive is adapted to operatively move the aeration unit along the track and thereby vary an elevation of the aeration unit. The universal wall and bridge mount supports the track and aeration unit. The universal wall and bridge mount has a first configuration for mounting to a structure such as a stationary bridge, and a second configuration for mounting to a wall. The universal wall and bridge mounted aeration apparatus may be adjusted to position the propeller after installation under the surface of the liquid through three axes of motion freedom.

FLEXIBLE DOCK-OUT TIME

A system including one or more processors and one or more non-transitory computer-readable media storing computing instructions configured to run on the one or more processors and perform: generating a feasible dock-out plan designed to deliver one or more orders to one or more physical stores based on a feasible route plan by: generating a preliminary dock-out time boundary based on one or more delivery time windows; determining an earliest dock-out time based at least in part on the preliminary dock-out time boundary and a backward search; and determining a latest dock-out time based at least in part on the preliminary dock-out time boundary and a forward search; and transmitting a range of dock-out times comprising (i) the earliest dock-out time and (ii) the latest dock-out time to a user. Other embodiments are described.

Multi-view 3D object recognition from a point cloud and change detection

A method of detecting objects in three-dimensional (3D) point clouds and detecting differences between 3D point clouds and the objects therein is disclosed. A method includes receiving a first scene 3D point cloud and a second scene 3D point cloud, wherein the first scene 3D point cloud and the second scene 3D point cloud include first and second target objects, respectively; aligning the first scene 3D point cloud and the second scene 3D point cloud; detecting the first and second target objects from the first scene 3D point cloud and the second scene 3D point cloud, respectively; comparing the detected first target object with the detected second target object; and identifying, based on the comparison, one or more differences between the detected first target object and the detected second target object. Further aspects relate to detecting changes of target objects within scenes of multiple 3D point clouds.

Horming response element binding transregulators

Disclosed are compositions and methods for ERE-binding tansregulators that specifically and potently regulate ERE-containing genes. To accomplish this, we took advantage of the modular nature of ER and initially designed a monomeric ERE binding module by co-joining two DNA binding domains with the hinge domain. Integradon of strong activation or repressor domains from other transcription factors into this module generated constitutively active ERE-binding activators (EBAs) and ERE-binding repressors (EBRs) respectively. These novel transregulators are the basis for the targeted regulation of ERE containing genes, the identification of estrogen reponsive gene networks, and the development of alternative/complementary therapeutic approaches for estrogen target tissue cancers.

SYSTEMS AND METHODS FOR VEHICLE ROUTING

Systems and methods including one or more processors and one or more non-transitory storage devices storing computing instructions configured to run on the one or more processors and cause the one or more processors to perform (1) receiving one or more first delivery routes comprising one or more delivery stops in a sequence; (2) shuffling the one or more delivery stops among the one or more first delivery routes to create one or more second delivery routes different than the one or more first delivery routes; (3) determining whether the one or more second delivery routes are on a list of banned delivery routes; (4) when (a) the one or more second delivery routes are not on the list of banned delivery routes and (b) a second cost of the one or more second delivery routes is lower than a first cost of the one or more first delivery routes, persisting the one or more second delivery routes in the one or more non-transitory computer-readable storage devices; and (5) repeating (2) through ( ...

Glutarate Compounds for Treating Ischemia-Reperfusion Injuries

Disclosed herein are methods of preventing, inhibiting, reducing, or treating ischemia and reperfusion injury to tissues with glutarate compounds such as α-ketoglutarate.

Multi-function power regulator for prioritizing functions and allocating resources thereof

A multi-function power regulator for prioritizing functions and allocating resources thereof, the multi-function regulator including a plurality of resources each having a resource capacity limit. The multi-function regulator also includes a shunt converter is configured to perform one or more shunt converter functions while consuming one or more of the resources, a series converter is configured to perform one or more series converter functions while consuming one or more of the resources. A control engine coupled to the shunt converter, the series converter, and a plurality of sensors, the control engine is configured to monitor and control the one or more shunt converter functions and the one or more series converter functions. The multi-function regulator also includes a priority control engine coupled to the control engine, the priority control engine is configured to set a priority order for performing the one or more shunt converter functions and/or the one or more series converter ...

IPv4 Data Center Support for IPv4 and IPv6 Visitors

A network element (NE) comprising a processor configured to transmit a message to a domain names system (DNS) server, wherein the message comprises a virtual service internet protocol (VSIP) version six (VSIPv6) address corresponding to a service associated with an internet protocol version four (IPv4) address. Also disclosed is a method comprising associating a remote host internet protocol (IP) version six (IPv6) address with a private IPv4 address in a stateful binding table, and associating a local service IPv4 address with a local service VSIPv6 address in a stateless binding table.

Alpha-Ketobutyrate, 2-Hydroxybutyrate, and Alpha-Ketoglutarate for Stimulating Hair Growth

Disclosed herein are methods and compositions for treating, inhibiting, or reducing hair loss, treating, inhibiting, or reducing pigmentation loss, improving or stimulating hair growth, and/or improving or stimulating pigmentation production in a subject with one or more alpha-ketobutyrate compounds and/or one or more glutarate compounds.

FLOW COMPENSATOR

An apparatus is disclosed including: a housing including a conduit having an inlet port and an outlet port; an insert at least partially disposed within the conduit and including a tapered portion extending from a narrower end proximal the inlet port to a wider end distal the inlet port; and a facility for adjusting the position of the insert within the conduit. In some embodiments, the apparatus is configured to receive a mixed flow of liquid and gas at the inlet port, direct the mixed flow through the conduit around a portion of the insert disposed within the chamber, and outlet the mixed flow at the outlet port.

COMPRESSION OF MACHINE LEARNING MODELS UTILIZING PSEUDO-LABELED DATA TRAINING

Embodiments are generally directed to compression in machine learning and deep learning processing. An embodiment of an apparatus for compression of untyped data includes a graphical processing unit (GPU) including a data compression pipeline, the data compression pipeline including a data port coupled with one or more shader cores, wherein the data port is to allow transfer of untyped data without format conversion, and a 3D compression/decompression unit to provide for compression of untyped data to be stored to a memory subsystem and decompression of untyped data from the memory subsystem.

COMPOSITIONS OF SACCHARIDE COATED NANOPARTICLES AND USES

This disclosure relates to nanoparticles of metals, alloys, metal oxides, and multi-metallic oxides comprising oligosaccharide coatings and uses such as in molecular imaging. Typically, the nanoparticles comprise iron oxide. In certain embodiments, the disclosure relates to compositions comprising iron oxide nanoparticles comprising a saccharide coating of less than 5 nm. In certain embodiments, the average core size is below 5 nm with highly uniform core size and a hydrodynamic size of not greater than 10 nm.

Multi-hop wireless network plannning

In one embodiment, a method includes accessing a point cloud comprising a plurality of point-cloud points, each point-cloud point corresponding to a location on a surface of an object located in a region in a three-dimensional space, identifying, from the point cloud, a plurality of point clusters, each point cluster comprising a plurality of point-cloud points located within a grid segment on a two-dimensional grid derived from the three-dimensional space, selecting, for each point cluster, a set of point-cloud points from the plurality of point-cloud points in the point cluster, the set of point-cloud points being selected based on a predetermined threshold number of point-cloud points associated with an acceptable reduction in an error detection rate, and determining, for each point cluster, a structure classification based on the selected set of point-cloud points from the point cluster.

MULTI-FUNCTION POWER REGULATOR FOR PRIORITIZING FUNCTIONS AND ALLOCATING RESOURCES THEREOF

A multi-function power regulator for prioritizing functions and allocating resources thereof, the multi-function regulator including a plurality of resources each having a resource capacity limit. The multi-function regulator also includes a shunt converter is configured to perform one or more shunt converter functions while consuming one or more of the resources, a series converter is configured to perform one or more series converter functions while consuming one or more of the resources. A control engine coupled to the shunt converter, the series converter, and a plurality of sensors, the control engine is configured to monitor and control the one or more shunt converter functions and the one or more series converter functions. The multi-function regulator also includes a priority control engine coupled to the control engine, the priority control engine is configured to set a priority order for performing the one or more shunt converter functions and/or the one or more series converter ...

ROUTE PLAN USING NON-HOMOGENOUS EQUIPMENT VIA OCEAN ROUTES

A system including one or more processors and one or more non-transitory computer-readable media storing computing instructions configured to run on the one or more processors and perform: obtaining orders for fulfillment to physical stores from a distribution center, wherein the orders are associated with stacks comprising temperature-controlled pallets and non-temperature-controlled pallets; splitting the orders based on a type of each order; determining containers that are available for driver shifts, wherein the containers comprise temperature-controlled containers each having multiple compartments and dry containers each having a single compartment; generating potential routes by assigning, using a utilization-guided search, the non-temperature-controlled pallets and the temperature-controlled pallets to compartments of the containers; determining, from the potential routes, solution routes that are feasible and minimize costs; and outputting the solution routes. Other embodiments ...

Method and apparatus for updating manner of processing packet of service flow

This application discloses a method and an apparatus for updating a manner of processing a packet of a service flow. The method includes a first packet of the service flow is forwarded by using a first service function chain (SFC). A control node obtains a flow identifier and indication information from a service function (SF) node of the first SFC, where the indication information is used to indicate a manner of processing a second packet of the service flow, the flow identifier is used to identify the service flow. The control node obtains the manner of processing the second packet according to the indication information, and sends the flow identifier and the manner of processing the second packet to the processing node, where the manner of processing the second packet does not include forwarding the second packet along the first SFC.

Methods for high throughput genotyping

Methods for genotyping polymorphisms using allele specific probes are disclosed. A training set is used to generate a model for each polymorphism to be interrogated. The training set is used to obtain an estimate of the asymmetry between an intensity measurement for a first allele and an intensity measurement for a second allele of the same polymorphism. The intensity measurement obtained for a test sample is adjusted using the estimate of asymmetry prior to using the intensity measurements to make a genotyping call. In preferred embodiments the adjustment is applied to polymorphisms that have a likelihood of being heterozygous that is above a specified threshold.

Service multiplexing method, service demultiplexing method, and related device

Embodiments of the present invention disclose a service multiplexing method. The method includes: sending, by a sending device, a bit block stream of a first service to a receiving device; if the sending device determines to switch from the first service to a second service for service sending, sending, by the sending device, at least one service switching indication bit block to the receiving device; and sending, by the sending device, a bit block stream of the second service to the receiving device. In addition, a service switching indication bit block is inserted between bit block streams that require service switching, to perform service switching, thereby reducing a latency and jitter in a service switching process, and ensuring a low latency during service switching.

METHODS AND SYSTEMS FOR DETECTING GENETIC FUSIONS TO IDENTIFY A LUNG DISORDER

Gene fusions are hybrid genes formed by two previously separate genes. Many such gene fusions may be strong driver mutations for cancer and may play important roles in tumorigenesis. Gene fusions may be identified in biological samples extracted from the diseased location. However, for lung cancer, extracting samples from the nodules may be challenging and may lead to undesirable consequences. Disclosed herein is a method and system of identifying a gene fusion landscape from bronchial brushings and further identifying fusions that may be potentially associated with lung cancer.

Method and apparatus for displaying unread message, electronic device, and storage medium

Embodiment of this application provide a method and apparatus for displaying an unread message, an electronic device, and a storage medium. The method includes: displaying a program corner mark in a case that an unread message is received through a target application; receiving a first input performed by a user on the program corner mark; displaying an information window in response to the first input, where the information window includes an identifier of a target contact, the target contact is a contact meeting a preset condition in contacts corresponding to the unread message, and receiving a second input performed by the user on the identifier of the target contact; and starting the target application in response to the second input.

Easy-tear sticker and protective film assembly

An easy-tear sticker and a protective film assembly are provided. The easy-tear sticker includes: a main body layer and a first adhesive layer, the main body layer includes an attaching part and a tearing part, and the first adhesive layer is disposed on the attaching part, the attaching part includes a first attaching area and a second attaching area, a shape of the first attaching area is a right-angle triangle, and a shape of the second attaching area is a strip; the tearing part is connected to the attaching part by a first right-angle side of the right-angle triangle, and the tearing part is configured to be folded toward the attaching part along the first right-angle side, so as to cover a surface of the attaching part facing away from the first adhesive layer.

Display panel protective glass and preparation method thereof, display panel and display device

The embodiments of the disclosure provide a display panel protective glass and a preparation method thereof, a display panel and a display device. The display panel protective glass comprises: a glass substrate; a white photoresist layer on the glass substrate, the white photoresist layer being arranged along a bezel region of the glass substrate; an isolation layer on the white photoresist layer; a black matrix layer on the isolation layer, the black matrix layer being arranged along the bezel region of the glass substrate.

METHOD, TERMINAL AND GATEWAY FOR TRANSMITTING IPV6 PACKET IN IPV4 NETWORK

The present disclosure provides a method, a terminal, and a gateway for transmitting IPv6 packets in an IPv4 network. An IPv6 terminal obtains an IPv6 address of the terminal, where the IPv6 address comprises an IPv4 address, the IPv4 address is an IPv4 address of a gateway or an IPv4 address designated by the gateway, the gateway is a device connecting an IPv6 network to an IPv4 network, or a device connecting a layer 2 network to an IPv4 network, multiple IPv6 terminals are connected to the gateway, and IPv6 addresses of all the IPv6 terminals connected to the gateway comprise the same IPv4 address; and sends an IPv6 packet to the gateway, where the IPv6 packet comprises the IPv6 address as a source address. In embodiments of the present disclosure, traversal of IPv6 packets through an IPv4 network can be implemented, and IPv4 address resources can be saved.

METHODS AND COMPOSITIONS THAT UTILIZE TRANSCRIPTOME SEQUENCING DATA IN MACHINE LEARNING-BASED CLASSIFICATION

Provided herein are methods and systems for producing a modified biological dataset by flagging or removing a nucleic acid sequence from the biological dataset that is assigned a noise-call to produce the modified biological dataset. The noise-call may be based on comparing a gene expression level, sequence information, or a combination thereof with a nucleic acid sequence of a control sample.

Sparse maximum a posteriori (MAP) adaptation

Techniques disclosed herein include using a Maximum A Posteriori (MAP) adaptation process that imposes sparseness constraints to generate acoustic parameter adaptation data for specific users based on a relatively small set of training data. The resulting acoustic parameter adaptation data identifies changes for a relatively small fraction of acoustic parameters from a baseline acoustic speech model instead of changes to all acoustic parameters. This results in user-specific acoustic parameter adaptation data that is several orders of magnitude smaller than storage amounts otherwise required for a complete acoustic model. This provides customized acoustic speech models that increase recognition accuracy at a fraction of expected data storage requirements.

Casein Coated Drug-Loaded Iron Oxide Nanoparticles

This disclosure relates to nanoparticle drug delivery systems composed of casein (CN) coated nanoparticles, e.g., iron oxide nanoparticles coated with an inner layer and an out layer comprising the milk protein casein. In certain embodiments, drug molecules are incorporated into an inner polymeric layer coating the nanoparticles, which are subsequently coated with a casein containing outer layer, i.e., a layer-by-layer (LBL) construction. Oral administration of these casein coated nanoparticles are contemplated as experiments indicated sufficiently stability in conditions that simulate the conditions of the gut. Drugs that were loaded into the nanoparticle systems were released when the casein outer layer was gradually degraded in the presence of an intestinal protease meant to simulate conditions of the intestine.

Glutarate Compounds for Treating Ischemia-Reperfusion Injuries

Disclosed herein are methods of preventing, inhibiting, reducing, or treating ischemia and reperfusion injury to tissues with glutarate compounds such as α-ketoglutarate.

Automatic generation of incremental load design with stacks of pallets

A system including one or more processors and one or more non-transitory computer-readable media storing computing instructions that, when executed on the one or more processors, perform certain acts. The acts can include obtaining information about a trailer that has been partially loaded with preloaded stacks in a manner that deviates from an original load design. The trailer is being loaded with stacks of pallets comprising the preloaded stacks and unloaded stacks. The acts also can include determining positions of empty floor spots remaining in the trailer. The acts additionally can include determining a first portion of an incremental load design for the unloaded stacks using a gap-filling pattern behind an uneven rear edge of the preloaded stacks. The acts further can include determining a second portion of the incremental load design. The acts additionally can include updating the incremental load design based on an overall load design of the trailer. The acts further can include ...

Water hammer-proof air valve and water hammer-proof exhaust method for in-use pipeline

A water hammer-proof air valve that has a valve body and a bonnet, that are fixedly connected, a valve opening is provided on the valve body, and a high-speed intake and exhaust device is provided in an inner cavity of the valve body. A bonnet opening is provided on the bonnet, an output end of the high-speed intake and exhaust device penetrates the bonnet opening and is communicated with a high-speed exhaust throttling device for limiting an exhaust amount of gas of the high-speed intake and exhaust device, an output end of the high-speed exhaust throttling device is communicated with an outside air, and a trace exhaust device for discharging the gas separated out from the pipeline to the outside through the high-speed exhaust throttling device after the high-speed intake and exhaust device closes the valve is further provided in the high-speed intake and exhaust device.

METHODS AND SYSTEMS FOR DETECTING USUAL INTERSTITIAL PNEUMONIA

The present disclosure provides systems, methods, and classifiers for differentiating between samples as usual interstitial pneumonia (UIP) or non-UIP.

Methods for identifying DNA copy number changes

Methods of identifying allele-specific changes in genomic DNA copy number are disclosed. Methods for identifying homozygous deletions and genetic amplifications are disclosed. An array of probes designed to detect presence or absence of a plurality of different sequences is also disclosed. The probes are designed to hybridize to sequences that are predicted to be present in a reduced complexity sample. The methods may be used to detect copy number changes in cancerous tissue compared to normal tissue. The methods may be used to diagnose cancer and other diseases associated with chromosomal anomalies.

System and method for performing driver configuration operations without a system reboot

A method and apparatus for performing driver configuration operations without a system reboot is disclosed. In one embodiment, a network server's adapter driver receives a request to change a configuration of a selected instance of a plurality of instances. In response, the adapter driver may then determine if there is data flow through the selected instance. If there is no data flow through the selected instance, the method includes blocking subsequent data flow and subsequent information requests issued to the adapter driver. The selected instance may then be reinitializing without rebooting the server.

Methods for high throughput genotyping

Methods for genotyping polymorphisms using allele specific probes are disclosed. A training set is used to generate a model for each polymorphism to be interrogated. The training set is used to obtain an estimate of the asymmetry between an intensity measurement for a first allele and an intensity measurement for a second allele of the same polymorphism. The intensity measurement obtained for a test sample is adjusted using the estimate of asymmetry prior to using the intensity measurements to make a genotyping call. In preferred embodiments the adjustment is applied to polymorphisms that have a likelihood of being heterozygous that is above a specified threshold.

Policy-based system interface for a real-time autonomous system

Embodiments are generally directed to compression in machine learning and deep learning processing. An embodiment of an apparatus for compression of untyped data includes a graphical processing unit (GPU) including a data compression pipeline, the data compression pipeline including a data port coupled with one or more shader cores, wherein the data port is to allow transfer of untyped data without format conversion, and a 3D compression/decompression unit to provide for compression of untyped data to be stored to a memory subsystem and decompression of untyped data from the memory subsystem.

INTERCELLULAR ADHESION MOLECULE 1 (ICAM1) ANTIBODY DRUG CONJUGATE AND USES THEREOF

The disclosure provides compositions comprising intercellular adhesion molecule 1 (ICAM1) antibody and methods for using the same for therapeutic applications, for example, treating triple negative breast cancer (TNBC) and predicting drug response.

Methods for identifying DNA copy number changes

Methods of identifying changes in genomic DNA copy number are disclosed. Methods for identifying homozygous deletions and genetic amplifications are disclosed. An array of probes designed to detect presence or absence of a plurality of different sequences is also disclosed. The probes are designed to hybridize to sequences that are predicted to be present in a reduced complexity sample. The methods may be used to detect copy number changes in cancerous tissue compared to normal tissue. The methods may be used to diagnose cancer and other diseases associated with chromosomal anomalies.

Automatic generation of route design

A system including one or more processors and one or more non-transitory computer-readable media storing computing instructions configured to run on the one or more processors and perform certain acts. The acts can include obtaining orders for fulfillment to physical stores from a distribution center. There can be one or more respective stack groups associated with each of the orders. The acts also can include generating a set of feasible route templates for delivering the orders to the physical stores. The acts additionally can include formulating a mixed integer programming formulation for an assignment of the respective stack groups associated with the orders to the set of route templates. The acts further can include using an optimization solver for the mixed integer programming formation to determine the assignment that minimizes an overall cost of delivering the orders to the physical stores from the distribution center. The acts additionally can include outputting the assignment.

Display panel and manufacturing method thereof

A display panel and a manufacturing method thereof are provided. The display panel includes a substrate, a first inorganic layer, an organic layer, and a water absorption laminated layer. The display panel manufacturing method includes a substrate provided step, a first inorganic layer formation step, an organic layer formation step, a second inorganic layer formation step, and a water absorption laminated layer formation step.

Casein coated drug-loaded iron oxide nanoparticles

This disclosure relates to nanoparticle drug delivery systems composed of casein (CN) coated nanoparticles, e.g., iron oxide nanoparticles coated with an inner layer and an out layer comprising the milk protein casein. In certain embodiments, drug molecules are incorporated into an inner polymeric layer coating the nanoparticles, which are subsequently coated with a casein containing outer layer, i.e., a layer-by-layer (LBL) construction. Oral administration of these casein coated nanoparticles are contemplated as experiments indicated sufficiently stability in conditions that simulate the conditions of the gut. Drugs that were loaded into the nanoparticle systems were released when the casein outer layer was gradually degraded in the presence of an intestinal protease meant to simulate conditions of the intestine.

Method and apparatus for forecasting characteristic information change

Method and apparatus for forecasting a characteristic information change. Historical characteristic data in at least one computation period and current incremental data of multiple pieces of first characteristic information corresponding to a pre-estimation model is acquired. The current incremental data is used for indicating a ratio of characteristic data on a day immediately before a forecasting day of each of the multiple pieces to the historical characteristic data in the at least one computation period of each of the multiple pieces of first characteristic information. A first change information on the forecasting day of second characteristic information is determined by a forecasting process using the pre-estimation model based on the historical characteristic data and the current incremental data. Based on the first change information, change pre-estimation information on the forecasting day of the second characteristic information is determined to prompt a user to execute a corresponding ...

Double chair

Hub of movable scroll device for scroll compressor including centroid-adjusting recess and method for manufacturing same

Disclosed are a movable scroll device for a scroll compressor and a method for manufacturing same. The method includes: manufacturing the movable scroll device by means of casting steps, so that the movable scroll device includes a movable scroll end plate, with a movable scroll blade provided on a first side face of the movable scroll end plate; and a hub vertically extending outwards from the middle of a second side face of the movable scroll end plate; and fabricating at least one centroid adjustment recess on the hub. By the method, the centroid of the movable scroll device can be adjusted in a more flexible, precise, active and targeted manner.

Methods for Nucleic Acid Sequencing

The present disclosure provides systems and methods for sequencing and analysis of nucleic acids.

Methods for identifying DNA copy number changes

Methods of identifying allele-specific changes in genomic DNA copy number are disclosed. Methods for identifying homozygous deletions and genetic amplifications are disclosed. An array of probes designed to detect presence or absence of a plurality of different sequences is also disclosed. The probes are designed to hybridize to sequences that are predicted to be present in a reduced complexity sample. The methods may be used to detect copy number changes in cancerous tissue compared to normal tissue. The methods may be used to diagnose cancer and other diseases associated with chromosomal anomalies.

METHOD FOR ALLOCATING AN EXTERNAL NETWORK IP ADDRESS IN NAT TRAVERSAL, AND DEVICE AND SYSTEM

Embodiments of the present disclosure provide a method for allocating an external network IP address in NAT traversal, and a device and a system. The method includes: receiving a request message sent by a client and is for establishing a NAT mapping entry corresponding to a connection, where the request message includes a designated external network IP address, and the external network IP address is the same as an external network IP address in a NAT mapping entry corresponding to any connection already established by a same application; and when the NAT mapping entry is established according to the received request message, allocating, according to the designated external network IP address in the request message, an IP address which is the same as the designated external network IP address and used as an external network IP address of the NAT mapping entry to be established.

Methods for identifying DNA copy number changes

Methods of identifying changes in genomic DNA copy number are disclosed. Methods for identifying homozygous deletions and genetic amplifications are disclosed. An array of probes designed to detect presence or absence of a plurality of different sequences is also disclosed. The probes are designed to hybridize to sequences that are predicted to be present in a reduced complexity sample. The methods may be used to detect copy number changes in cancerous tissue compared to normal tissue. The methods may be used to diagnose cancer and other diseases associated with chromosomal anomalies.

Preparation and applications of novel complexes made by gamma-polyglutamic acid and cisplatin

A series of complexes made by γ-polyglutamic acid (γ-PGA) and cisplatin, their preparation and applications in biomedical field, specifically in cancer treatment. The complexes may be made by binding free cisplatin on small molecule γ-PGA through the reaction between carboxylic group of γ-PGA and Cl of cisplatin. The complexes show effective anticancer effect and are easy and cost effective to prepare.

Data transfer method and virtual switch

A data transfer method and a virtual switch, where when receiving a data packet, the virtual switch extracts characteristic information of the data packet, and determines, based on the extracted characteristic information of the data packet, whether an expedited forwarding rule is configured for a data stream to which the data packet belongs. If the expedited forwarding rule is configured for the data stream to which the data packet belongs, the virtual switch bypasses a LINUX bridge to directly send the data packet to a receive end, thereby reducing times of data packet switching between a kernel mode and a user mode, and improving data packet forwarding efficiency.

Impedance Measurement Using Line-to-Line Current Injection

An unbalanced line-to-line current is injected at an injected frequency in a three-phase ac circuit. A first set of voltages and currents are obtained. A first set of transformed voltages and transformed currents are produced. The circuit is injected with a second unbalanced line-to-line current at a frequency linearly independent of the injected frequency. A second set of voltages and current are obtained. A second set of transformed voltages and transformed currents are produced The impedance of a source portion and a load portion of the circuit are calculated using the first and second set of transformed voltages, and the first and second set of transformed currents.

System and method for relation extraction with adaptive thresholding and localized context pooling

System and method for relation extraction using adaptive thresholding and localized context pooling (ATLOP). The system includes a computing device, the computing device has a processer and a storage device storing computer executable code. The computer executable code is configured to provide a document; embed entities in the document into embedding vectors; and predict relations between a pair of entities in the document using their embedding vectors. The relation prediction is performed based on an improved language model. Each relation has an adaptive threshold, and the relation between the pair of entities is determined to exist when a logit of the relation between the pair of entities is greater than a logit function of the corresponding adaptive threshold.

Method for detecting content of optical isomers of bortezomib

The invention discloses a method for detecting the content of optical isomers of bortezomib. The method is a high-performance liquid chromatography and comprises the steps as follows: a normal-phase chromatographic column with an amylase tris(3,5-dimethylphen-ylcarbamate) chiral stationary phase serving as a filler is adopted for coating the surface of silica gel, a mixed solvent of n-hexane, alcohol and an organic amine polarity modifier serves as a mobile phase, wherein the volume ratio of the n-hexane, the alcohol and the organic amine polarity modifier is (97-95):(3-5):(0-0.5), an ultraviolet detector is used for detection, the flow velocity is in a range of 1.0-1.4ml/min, and the temperature of the chromatographic column is in a range of 25-45 DEG C. According to the method, four optical isomers of the bortezomib can be well separated, so that the content of each optical isomer in the bortezomib can be measured accurately. The method is stable, reliable, high in sensitivity and applicable ...

METHOD AND SYSTEM FOR MOUSE POINTER TO AUTOMATICALLY FOLLOW CURSOR

Embodiments of the present application disclose a method for controlling a mouse pointer to automatically follow a cursor. During operation, the system detects whether the cursor is in a currently active window displayed on a screen of a computing device. In response to detecting that the cursor is in the currently active window, the system obtains coordinates of the cursor. The system then calculates follow coordinates according to the coordinates of the cursor and a predetermined distance value. The system subsequently sets coordinates of the mouse pointer to the follow coordinates.

Data Transfer Method and Virtual Switch

A data transfer method and a virtual switch, where when receiving a data packet, the virtual switch extracts characteristic information of the data packet, and determines, based on the extracted characteristic information of the data packet, whether an expedited forwarding rule is configured for a data stream to which the data packet belongs. If the expedited forwarding rule is configured for the data stream to which the data packet belongs, the virtual switch bypasses a LINUX bridge to directly send the data packet to a receive end, thereby reducing times of data packet switching between a kernel mode and a user mode, and improving data packet forwarding efficiency.

SYSTEMS AND METHODS FOR VEHICLE ROUTING

Systems and methods including one or more processors and one or more non-transitory storage devices storing computing instructions configured to run on the one or more processors and cause the one or more processors to perform receiving one or more orders comprising a list of one or more pallets; grouping each pallet of the one or more pallets into one or more groups using one or more respective qualities of each respective pallet; for each group of the one or more groups, building one or more stacks of pallets using at least three different stacking models; selecting a final stack list of a model of the at least three different stacking models having a lowest number of stacks; and optimizing the final stack list using a probabilistic model. Other embodiments are disclosed herein.

METHODS FOR NUCLEIC ACID SEQUENCING

The present disclosure provides systems and methods for sequencing and analysis of nucleic acids.

SYSTEMS AND METHODS FOR INVERTER AND DC/DC CONVERTER OPERATION

Examples of the disclosure include a power system comprising a power-system output configured to be coupled to, and provide an output AC waveform to, one or more loads, a positive DC bus, a negative DC bus, an inverter coupled to the positive DC bus and the negative DC bus, the inverter including an inverter output coupled to the power-system output, and a DC/DC converter coupled between the inverter output and at least one of the positive DC bus or the negative DC bus.

PRODRUGS OF ALPHA-KETOGLUTARATE, ALPHA-KETOBUTYRATE, ALPHA-KETOISOVALERATE, AND ALPHA-KETOISOHEXANOATE, AND USES THEREOF

The present disclosure provides compounds and compositions capable of extending lifespan, and methods of use thereof.

Encapsulation method for OLED Panel

The invention provides a encapsulation method for OLED panel, by forming an organic defining film surrounding the OLED device on the substrate, then using ALD process to form an inorganic film on the substrate and OLED device covering the package region and then removing the organic defining film to obtain an ALD film corresponding to the above of the package region, and finally forming a package film on ALD film corresponding to the above of the package region complete encapsulation the OLED panel. The present invention uses an organic defining film to realize selective atomic layer deposition, thereby avoiding using the atomic layer deposition mask and related cleaning and replacement problems. The process is relatively simple, thus saving costs, and the resulted package structure meets the encapsulation requirements of flexible OLED panel, able to effectively block the external water oxygen to protect the OLED device.

SYSTEMS AND METHODS FOR VEHICLE ROUTING

Systems and methods including one or more processors and one or more non-transitory storage devices storing computing instructions configured to run on the one or more processors and perform acts of (1) receiving one or more orders; (2) inserting the one or more orders into a plurality of pre-constructed routes to create a plurality of modified routes; (3) selecting a route of the plurality of modified routes with a lowest cost; (4) generating an initial load plan for the route with the lowest cost; (5) when the initial load plan does not pass one or more feasibility checks, splitting the one or more orders into two or more orders; and (6) repeating (1) through (5) until no more orders remain. Other embodiments are disclosed herein.

Data transmission method, apparatus, and system

This disclosure relates to a data transmission method, apparatus, and system, and belongs to the field of communications technologies. The data transmission method includes: obtaining, by a first node, m (m≥2) first FlexE clients, mapping the m first FlexE clients to one second FlexE client, and transmitting data of the second FlexE client to a second node, where data of each first FlexE client occupies a fixed timeslot of the second FlexE client, and the second node is different from the first node. In this disclosure, a problem in a related technology that a relatively fine granularity of a FlexE client imposes a relatively strict requirement on data processing performance of a node is resolved, and a plurality of first FlexE clients are mapped to one second FlexE client.

Ketobutyrate compounds and compositions for treating age-related symptoms and diseases

Disclosed herein are methods for (a) treating, inhibiting, or reducing aging of a subject, (b) treating, inhibiting, or reducing an age-related symptom or an age-related disease in a subject, and/or (c) increasing the lifespan of a subject which comprise administering to the subject one or more ketobutyrate compounds and compositions thereof.

Methods for identifying DNA copy number changes

Methods of identifying allele-specific changes in genomic DNA copy number are disclosed. Methods for identifying homozygous deletions and genetic amplifications are disclosed. An array of probes designed to detect presence or absence of a plurality of different sequences is also disclosed. The probes are designed to hybridize to sequences that are predicted to be present in a reduced complexity sample. The methods may be used to detect copy number changes in cancerous tissue compared to normal tissue. The methods may be used to diagnose cancer and other diseases associated with chromosomal anomalies.

Flexible ethernet group establishment method and device

This application discloses a flexible Ethernet group establishment method and a device. The method includes: determining that there are at least M physical layer PHY links; receiving at least M delay test requests sent by a near-end device; determining, by the far-end device, at least M receiving time points at which the at least M delay test requests are received; and determining M PHY links used to establish a flexible Ethernet group, from the at least M PHY links based on the at least M receiving time points, where a delay difference between any two of the M PHY links satisfies a preset delay condition. According to the method in this application, the delay difference between the any two PHY links is accurately determined based on time points at which delay test requests are received over any two PHY links.

CLINICAL CLASSIFIERS AND GENOMIC CLASSIFIERS AND USES THEREOF

Provided herein are methods and systems for analyzing a sample of a subject to determine whether the subject has, or is at risk of having or developing, a cancer, such as lung cancer.

METHODS FOR HIGH THROUGHPUT GENOTYPING

Methods for genotyping polymorphisms using allele specific probes are disclosed. A training set is used to generate a model for each polymorphism to be interrogated. The training set is used to obtain an estimate of the asymmetry between an intensity measurement for a first allele and an intensity measurement for a second allele of the same polymorphism. The intensity measurement obtained for a test sample is adjusted using the estimate of asymmetry prior to using the intensity measurements to make a genotyping call. In preferred embodiments the adjustment is applied to polymorphisms that have a likelihood of being heterozygous that is above a specified threshold.

Multi-hop wireless network planning

In one embodiment, a method includes accessing a point cloud comprising several points, wherein each point corresponds to a location on a surface of an object located in three-dimensional space; determining whether each point in the point cloud is part of a linear structure, a planar structure, or a volumetric structure; identifying a plurality of point clusters, wherein each point cluster comprises one or more points that are located within a grid segment on a two-dimensional grid derived from the three-dimensional space; determining, for each point cluster, whether the point cluster represents a vertical-linear structure or a portion of a vertical-linear structure; identifying one or more point-cluster pairs, wherein each point-cluster pair includes two point clusters corresponding to one or more vertical-linear structures within a threshold distance in the three-dimensional space; and determining, for each point-cluster pair, whether a line-of-sight exists between each point-cluster ...

Ligand binding stabilization method for drug target identification

Drug affinity responsive target stability (DARTS) is a method of drug target ID with several significant advantages over current techniques. In certain embodiments the method involves contacting a sample comprising one or more protein target(s) with a test agent to form a sample/test agent mixture; contacting the mixture with a protease; and identifying a protein or protein fragment that is protected from proteolysis, wherein the protection from proteolysis is an indicator that the protein or protein fragment binds to or interacts with the test agent.

Universal bridge and wall mounted aeration apparatus

A universal wall and bridge mounted aeration apparatus has a track extending between two distinct elevations that is coupled to a wall and bridge mount. An aeration unit is pivotally coupled to the track and has an aerator adapted to operatively at least partially submerge within and aerate a liquid. A selective mover or drive is adapted to operatively move the aeration unit along the track and thereby vary an elevation of the aeration unit. The universal wall and bridge mount supports the track and aeration unit. The universal wall and bridge mount has a first configuration for mounting to a structure such as a stationary bridge, and a second configuration for mounting to a wall. The universal wall and bridge mounted aeration apparatus may be adjusted to position the propeller after installation under the surface of the liquid through three axes of motion freedom.

Intelligent in-vehicle air-quality control

A mechanism is provided for controlling the internal air-quality of a vehicle, including determining a changing trend of the in-vehicle air-quality based on acquired in-vehicle sensor data and usage status of the vehicle and responsive to the determined changing trend of the in-vehicle air-quality, signaling a control system of the vehicle to control the usage status of the vehicle based on a control policy.

Methods for assessing the risk of disease occurrence or recurrence using expression level and sequence variant information

Provided herein are methods, systems and kits for stratification of risk of disease occurrence of a sample obtained from a subject by combining two or more feature spaces to improve individualization of subject management.

Tilting disc check valve

The invention discloses a tilting disc check valve, which includes a left valve body ( 1 ), a right valve body ( 2 ), a large valve plate ( 3 ), a small valve plate ( 4 ) and a diaphragm control group ( 5 ), wherein the left valve body ( 1 ) and the right valve body ( 2 ) are butted into a whole through oblique openings; the oblique openings are inclined in a manner that upper parts are inclined towards the right valve body ( 2 ); the diaphragm control group ( 5 ) is arranged on the left valve body ( 1 ); the large valve plate ( 3 ) is arranged along the oblique openings; the large valve plate ( 3 ) is positioned in a valve cavity formed by the left valve body ( 1 ) and the right valve body ( 2 ); the large valve plate ( 3 ) is suspended on shaft holes of the left valve body ( 3 ) through valve shafts ( 6 ); the small valve plate ( 4 ) is connected with the diaphragm control group ( 5 ); and the small valve plate ( 4 ) is mounted at a slow closing valve port of the large valve plate ( 3 ) through a small valve plate pin shaft ( 7 ). According to the tilting disc check valve, a two-stage valve closing process where the large valve plate is quickly closed and the small valve plate at a drain hole of the large valve plate is slowly closed within adjustable time can be implemented, and the aims of reducing backflow of a water body and eliminating pump starting and stopping water hammer are fulfilled.

Self-structured machine learning classifiers

Techniques for generating machine learning architectures are provided. A data set is received for training one or more machine learning (ML) models, where the data set comprises labeled exemplars for a plurality of classes. The data set is partitioned into a training set and a testing set. A first ML model is trained using the training set, and a quality of the first ML model with respect to each class of the plurality of classes is evaluated using the testing set. Upon determining that the quality of the first ML model is below a predefined threshold with respect to a first class and a second class of the plurality of classes, a subset of the training set is identified, where each exemplar in the subset corresponds to either the first class or the second class. A second ML model is trained using the subset of the training set.

Heart rate detection system and wearable device using the same

Disclosed are a heart rate detection system and a wearable device using the same. The heart rate detection system includes a light emitting unit, a light sensor and a processor. The light emitting unit emits a light to a human body. The light sensor senses a reflected light of the light and accordingly generates a first electric signal. The processor calculates the low-frequency noise signal and the high-frequency noise signal of the first electric signal, and removes them. After that, the processor executes a peak detection with respect to the first electric signal to calculate peak values of the first electric signal, and calculate a heart rate based on the time intervals among the peak values.

Method, device, and system for quickly informing cgn exception

A method applicable to a commonest application scenario, the method includes: an AR receives a first packet sent in a unicast manner by a CGN. The first packet includes information for indicating Restart announce, the first packet's source address is the CGN's address, and the first packet's destination address is the AR's address; AR changes the first packet's destination address to an address of a CPE connected to the AR, to obtain a second packet, where the AR and the CPE are connected by using a Layer 2 network, and the CPE's address is a multicast address; and the AR sends the second packet. The method is used for quickly informing, after the CGN restarts or undergoes an active/standby switchover, the CPE that an exception occurs, for example, the CGN restarts or undergoes an active/standby switchover, so that a CGN has relatively small load when recreating NAT mapping.

Enzyme-free colorimetric immunoassay

A colorimetric immunoassay of the present invention uses nanostructured material with high absorption and high scattering ability as a label material for biosensors. Subject matters to be measured may be characterized or quantified by determining the changes in optical properties of the nanostructured material. The biosensor of the present invention may be operated in broad light wavelength range and detected by direct observation with naked eye. The biosensor of the present invention may be also provided with advantages such as higher sensitivity and lower cost.

Method of manufacture oled thin-film encapsulation layer, oled thin-film encapsulation structure and oled structure

A method of manufacture OLED thin-film encapsulation layer, an OLED thin-film encapsulation structure and an OLED structure are provided. The method of manufacture OLED thin-film encapsulation layer comprises following steps. Depositing a first inorganic material layer on a substrate positioning an OLED element, the first inorganic material layer is totally covered the OLED element; Depositing a first organic material layer on the first inorganic material layer by PECVD process; Depositing a second organic material layer on the first organic material layer by IJP process; Depositing a second inorganic material layer on the second organic material layer. The advantageous of this disclosure could decreases thickness of the OLED thin-film encapsulation layer.

Method and apparatus for updating manner of processing packet of service flow

This application discloses a method and an apparatus for updating a manner of processing a packet of a service flow. The method includes a first packet of the service flow is forwarded by using a first service function chain (SFC). A control node obtains a flow identifier and indication information from a service function (SF) node of the first SFC, where the indication information is used to indicate a manner of processing a second packet of the service flow, the flow identifier is used to identify the service flow. The control node obtains the manner of processing the second packet according to the indication information, and sends the flow identifier and the manner of processing the second packet to the processing node, where the manner of processing the second packet does not include forwarding the second packet along the first SFC.

Object classification based on decoupling a background from a foreground of an image

Techniques facilitating object classification based on decoupling a background from a foreground of an image are provided. A system can comprise a memory that stores computer executable components and a processor that executes the computer executable components stored in the memory. The computer executable components can comprise a model that is trained on images that comprise respective backgrounds and respective foregrounds that are interleaved. The model can be trained to detect the respective backgrounds with a defined confidence level. The computer executable components can also comprise an extraction component that employs the model to identify a background of a received image based on the defined confidence level and to decouple a foreground object of the received image based on identification of the background of the received image.

Fusion protein capable of self-assembling into protein nanoparticles and application thereof

The present invention relates to a recombinant fusion protein and a polysaccharide conjugate vaccine. More specifically, the present invention relates to a fusion protein including a pentamer substrate protein and a peptide sequence capable of forming a trimer, an immunogenic composition including the fusion protein, the application of the fusion protein in immunology, a polynucleotide sequence encoding the fusion protein, an expression vector containing the polynucleotide sequence, and a host cell containing the expression vector.

Facilitation of efficient signal source location employing a coarse algorithm and high-resolution computation

Facilitation of determination of detailed location of a source signal is provided. In one embodiment, a device comprises a memory that stores computer executable components; and a processor that executes computer executable components stored in the memory. The computer executable components can comprise: a low-resolution computation logic component that implements a coarse algorithm and determines an approximate direction of arrival (DOA) of a source signal of an input signal, wherein the coarse algorithm uses both a coarse spatial grid and input data received from the input signal to determine the approximate DOA; and an error estimation logic component that estimates an estimation error of the coarse algorithm, and wherein the error estimation logic component uses the estimation error and the approximate DOA to determine a spatial interval range.

Method for packet tunneling through software defined network, method of intelligently controlling flow of a packet through software defined network and system

Embodiments of the disclosure provide a method for packet tunneling through a software defined network (SDN), a method of intelligently controlling flow of a packet through an SDN network, and a system. The method for packet tunneling through an SDN includes: sending programmable instructions to an SDN controller from a processor executing an application program that includes the programmable instructions; wherein the programmable instruction comprises primitive operations regarding processing a packet for tunneling in accordance with a tunneling protocol; configuring a flow table by the first SDN controller in accordance with the programmable instructions; and processing and distributing the packet in accordance with the flow table by the SDN switch. The method may enable a system support multiple tunneling technologies without complicating the implementation of the SDN switch, and enable the system support new tunneling technologies without the need for updating the SDN switch, thereby reducing complexity of the SDN switch.

Intercellular adhesion molecule 1 (icam1) antibody drug conjugate and uses thereof

The disclosure provides compositions comprising intercellular adhesion molecule 1 (ICAM1) antibody and methods for using the same for therapeutic applications, for example, treating pancreatic cancer and predicting drug response.

Sparse maximum a posteriori (map) adaption

Techniques disclosed herein include using a Maximum A Posteriori (MAP) adaptation process that imposes sparseness constraints to generate acoustic parameter adaptation data for specific users based on a relatively small set of training data. The resulting acoustic parameter adaptation data identifies changes for a relatively small fraction of acoustic parameters from a baseline acoustic speech model instead of changes to all acoustic parameters. This results in user-specific acoustic parameter adaptation data that is several orders of magnitude smaller than storage amounts otherwise required for a complete acoustic model. This provides customized acoustic speech models that increase recognition accuracy at a fraction of expected data storage requirements.

Efficient defect localization/segmentation for surface defect inspection

A computer implemented method for surface defect inspection that includes recording an optical image of a surface including a defect; converting the optical image including the defect into a heat map; extracting a region of interest including the defect from the heat map; and comparing the region of interest including the defect from the heat map to a binary classification model using a sliding window based voting mechanism to determine if the defect is greater than or less than a threshold failure value.

Nonwoven fabric and polyurethane composite materials and methods for producing the same

The disclosure provides a composite material of nonwoven fabric and polyurethane produced without use of an adhesive and a method for producing the same. The composite material comprises a nonwoven fabric and a nonporous or porous polyurethane film, wherein the polyurethane film is laminated on the nonwoven fabric. The disclosure provides a method for producing the composite material as described above, comprising the steps of: firstly casting a polyurethane solution on a substrate so as to form a film, then laminating the film and a nonwoven fabric by flexibly adjusting the lamination process so as to form a composite material comprising the nonporous or porous polyurethane film and the nonwoven fabric. The composite material comprising a nonporous polyurethane film and a nonwoven fabric can be used for medical articles such as surgical gowns and drapes and the like, and the composite material comprising a porous polyurethane film and a nonwoven fabric can be used for medical articles such as absorbent pads, adhesive bandages, wound dressings and the like.

Method and apparatus for forecasting characteristic information change

Method and apparatus for forecasting a characteristic information change. Historical characteristic data in at least one computation period and current incremental data of multiple pieces of first characteristic information corresponding to a pre-estimation model is acquired. The current incremental data is used for indicating a ratio of characteristic data on a day immediately before a forecasting day of each of the multiple pieces to the historical characteristic data in the at least one computation period of each of the multiple pieces of first characteristic information. A first change information on the forecasting day of second characteristic information is determined by a forecasting process using the pre-estimation model based on the historical characteristic data and the current incremental data. Based on the first change information, change pre-estimation information on the forecasting day of the second characteristic information is determined to prompt a user to execute a corresponding operation.

Compression in machine learning and deep learning processing

Embodiments are generally directed to compression in machine learning and deep learning processing. An embodiment of an apparatus for compression of untyped data includes a graphical processing unit (GPU) including a data compression pipeline, the data compression pipeline including a data port coupled with one or more shader cores, wherein the data port is to allow transfer of untyped data without format conversion, and a 3D compression/decompression unit to provide for compression of untyped data to be stored to a memory subsystem and decompression of untyped data from the memory subsystem.

Training a self-driving vehicle

One or more sensors associated with a vehicle detect a roadway condition of a first roadway and an evasive maneuver is performed by the vehicle to avoid the detected roadway condition. In response to one or more processors determining that the evasive maneuver was successful, a record of the successful maneuver and the roadway condition are stored in a database. Subsequent to storing the record in the database, one or more computers associated with one or more vehicles is trained to execute the evasive maneuver, in response to determining that the one or more vehicles is exposed to the roadway condition experienced by the vehicle.

Audio source identification

Embodiments facilitating audio source identification are provided. A computer-implemented method comprises: receiving, by a device operatively coupled to one or more processors, an audio signal under inspection; generating, by the device, an image of time-frequency spectrum of low frequency component and high frequency component of the audio signal; and identifying, by the device, a source of the audio signal based on the generated image and one or more patterns of time-frequency spectrum, wherein each of the one or more patterns is corresponding to low frequency feature and high frequency feature of a specific audio source.

Automatic generation of load design

A system including one or more processors and one or more non-transitory computer-readable media storing computing instructions configured to run on the one or more processors and perform certain acts. The acts can include obtaining a route for delivering one or more orders in a trailer from a distribution center to physical stores in a sequence of stops. The route can have an associated assignment of stack groups comprising stacks of pallets. The acts also can include determining a load design for the stacks in the trailer based on the sequence of the stops in the route. The acts additionally can include updating the load design using a first simulated annealing to adjust a front-to-rear center-of-gravity of the load design. The acts further can include updating the load design using a second simulated annealing to adjust a side-to-side center-of-gravity of the load design. The acts additionally can include outputting the load design, as updated by the first simulated annealing and the second simulated annealing. The load design can specify a respective floor spot assignment for each of the stacks. Other embodiments are described.

Dynamic current correlating circuit and its applied comparator and analog-to-digital converter

A dynamic current correlating circuit is disclosed. The current correlating circuit includes a reset circuit, a first current generating circuit and a second current generating circuit. The reset circuit executes a discharging procedure during a first time interval and executes a charging procedure during a second time interval. The first current generating circuit is electrically connected to the reset circuit. The first current generating circuit generates a first sub-current and a second sub-current during a third time interval according to a first input voltage and a second input voltage and generates a first current after the third time interval. The second current generating circuit is electrically connected to the reset circuit. The second current generating circuit generates a second current according to the first input voltage and the second input voltage after the third time interval.

Liquid Ingesting Management System

A liquid ingesting management system is provided. The liquid ingesting management system includes a fluid container, a database and a wireless transmit/receive unit. The wireless transmit/receive unit communicates with the fluid container and the database through a wireless technique to access the database and control the fluid container to perform a liquid ingesting management process.

Intelligent in-vehicle air-quality control

A mechanism is provided for controlling the internal air-quality of a vehicle. In-vehicle sensor data of a vehicle are acquired and the usage status of the vehicle is determined based on the acquired in-vehicle sensor data. Based on the acquired in-vehicle sensor data and the determined usage status, a changing trend of the in-vehicle air-quality is determined and responsive to the determined changing trend of the in-vehicle air-quality, a control system of the vehicle is signaled to control the usage status of the vehicle based on a control policy.

Display panel protective glass and preparation method thereof, display panel and display device

The embodiments of the disclosure provide a display panel protective glass and a preparation method thereof, a display panel and a display device. The display panel protective glass comprises: a glass substrate; a white photoresist layer on the glass substrate, the white photoresist layer being arranged along a bezel region of the glass substrate; an isolation layer on the white photoresist layer; a black matrix layer on the isolation layer, the black matrix layer being arranged along the bezel region of the glass substrate.

Silicon wafer edge protection device with collision protection function

A wafer edge protection apparatus, including an electrical control module having a servomotor, a vertical motion mechanism and a protection mechanism. The protection mechanism includes: a shaft coupler, in fixed connection with a shaft of the servomotor and having a plurality of first connecting components; and a transmission sleeve, in fixed connection with the vertical motion mechanism and having a plurality of second connecting components in movable connection with the plurality of first connecting components. The plurality of first connecting components is in movable connection with the plurality of second connecting components such that, in the event of a torque output by the shaft of the servomotor not exceeding a limit, the plurality of first connecting components is engaged with the plurality of second connecting components, and in the event of the torque output by the shaft of the servomotor exceeding the limit, the plurality of first connecting components is disengaged from the plurality of second connecting components, thereby preventing a rotational motion generated by the servomotor from transferring to the vertical motion mechanism.

Anaerobic ammoxidation synergistic nitrogen removal process device of municipal sewage main and side streams and application method thereof

Provided are an anaerobic ammoxidation synergistic nitrogen removal process device of municipal sewage main and side streams and an application method thereof, comprising a municipal sewage raw water tank (1), a biological reaction pool (2), a secondary sedimentation pool (3), a sludge digestion solution raw water tank (4) and a sludge digestion solution AOB strengthening pool (5); wherein, the municipal sewage raw water tank (1) is connected with a water inlet valve (2.2) of the biological reaction pool (2) through a water inlet pump (2.1) of the biological reaction pool (2); the biological reaction pool (2) is connected with the secondary sedimentation pool (3) through a secondary sedimentation pool connection pipe (3.3); the sludge digestion solution raw water tank (4) is connected with a water outlet valve (4.1) of the sludge digestion solution raw water tank (4) through a water inlet pump (4.2) of the sludge digestion solution raw water tank (4); the sludge digestion solution AOB strengthening pool (5) is connected with an anaerobic ammoxidation region compartment of the biological reaction pool through a sludge-water mixture reflux pipe (5.8) and a sludge-water mixture reflux pump (5.11). It has the advantages of reasonability in structure design, convenience in operation, low running and maintenance cost, relatively low energy consumption, no need of an additional carbon source and the like, it can realize that short distance nitrification of municipal sewage is more stable, and it is high in low-temperature, water quantity and water quality shock resistance and can further increase volumetric load at the same time.

Suspending liquid or solution for organic optoelectronic device, making method thereof, and applications

Shock-absorbing cushion

Shock absorbing cushion structures are disclosed which are formed by upper and lower sheets peripherally sealed and formed to define a series of intercommunicating air chambers therebetween. In particular there is disclosed a shock absorbing shoe insole of this kind in which a flowable substance such as a medicinal or deodorant power is contained in the air chambers. The upper sheet is provided with an array of pinholes through which the flowable substance is released into a shoe by the application of pressure to the insole during walking. Also disclosed is a technique for making insoles in a range of sizes from a single molding.

Cinamic compounds and derivatives therefrom for the inhibition of histone deacetylase

The invention relates to a compound represented by the following formula (I): and pharmaceutically acceptable salts, stereoisomers, enantiomers, prodrugs and solvates thereof. The compounds are useful as an agent for enhancing the neurite outgrowth and preventing or treating of diseases associated with HDAC in particular, tumor or cell proliferative diseases. In particular, the compounds of the invention can be used as an agent for anti-cancer, anti-diabetic, and anti-neurodegenerative diseases such as Alzheimer's disease, Huntington's disease, Spinocerebellar Ataxias (SCA), and human spinal muscular atrophy (SMA).

Electrical connector for eliminating electromagnetic interference and terminal assembly thereof

Refinements to the rational polynomial coefficient camera model

An RPC camera model is applied to a set of intermediate object-space coordinates, where the intermediate object-space coordinates are determined by scaling, translating and rotating original object-space coordinates. The resulting image-space coordinates may be seen to more accurately remove residual error or bias that may exist for one or more of the imaging parameters on which the RPC camera model is based. The RPC camera model thus refined may then be used for photogrammetric processing of associated satellite imagery, including block adjustment, 3D feature extraction and orthorectification. Alternatively, a new RPC camera model (i.e., new coefficients) may be determined based on scaling, translating and rotating parameters. The new RPC camera model may then be applied to the original object-space coordinates to determine image-space coordinates.

Electrical connector

Methods and compositions for hair growth by activating autophagy

Liquid ingesting management system

A liquid ingesting management system is provided. The liquid ingesting management system includes a fluid container, a database and a wireless transmit/receive unit. The wireless transmit/receive unit communicates with the fluid container and the database through a wireless technique to access the database and control the fluid container to perform a liquid ingesting management process.

Glutarate compounds for treating ischemia-reperfusion injuries

Disclosed herein are methods of preventing, inhibiting, reducing, or treating ischemia and reperfusion injury to tissues with glutarate compounds such as α-ketoglutarate.

Process for the manufacture of substituted 2-cyano cinnamic esters

The invention relates to an improved process for the manufacture of substituted 2-cyanocinnamic esters. This novel economical process provides products in high purity and yields.

Methods for identifying DNA copy number changes

Methods of identifying allele-specific changes in genomic DNA copy number are disclosed. Methods for identifying homozygous deletions and genetic amplifications are disclosed. An array of probes designed to detect presence or absence of a plurality of different sequences is also disclosed. The probes are designed to hybridize to sequences that are predicted to be present in a reduced complexity sample. The methods may be used to detect copy number changes in cancerous tissue compared to normal tissue. The methods may be used to diagnose cancer and other diseases associated with chromosomal anomalies.

Display device for displaying images involving display pixels and non-display pixels

Display devices for displaying images are provided. A representative display device incorporates a display panel that includes a display pixel and a non-display pixel. The display pixel includes at least one switching thin-film transistor and the non-display pixel includes dummy thin-film transistors. A number of the dummy thin-film transistors exceeds a number of the switching thin-film transistors.

Dynamic current correlating circuit and its applied comparator and analog-to-digital converter

本發明揭露一種動態電流關聯電路，其包括一重置電路、一第一電流產生電路以及一第二電流產生電路。重置電路係於一第一時間執行一放電程序，並於一第二時間執行一充電程序。第一電流產生電路係與重置電路電性連接，並依據一第一輸入電壓及一第二輸入電壓，而於一第三時間產生一第一子電流及一第二子電流，並於第三時間之後產生一第一電流。第二電流產生電路係與重置電路電性連接，並依據第一輸入電壓及第二輸入電壓，而於第三時間之後產生一第二電流。另外，本發明亦揭露一種應用該動態電流關聯電路之比較器及類比數位轉換裝置。

Methods of treating hematological malignancies

The present invention relates, in general, to methods of treating malignancies and, in particular, to methods of treating hematological malignancies and to compositions suitable for use in such methods.

Optoelectronic device and method for producing the same

Embodiments of this invention disclose optoelectronic devices and their producing methods. The embodiments employ solution processes to produce p-type transition metal oxide layer, active layer, and n-type transition metal oxide layer of the optoelectronic devices. The p-type transition metal oxide layer comprises a copper oxide (CuO) layer or a nickel oxide (NiO) layer or a mixing layer, which comprises CuO or NiO mixed with an n-type transition metal oxide.

Multi-media memory card with intelligent card chip

Tumor cytotoxicity induced by modulators of the cxcr4 receptor

The present invention provides a means of selectively killing epithelial cell carcinomas by administering a CXCR4-specific sequence of the Gp120 protein or Nef proteins or the proteins themselves (the modulators) such as that found in strains HIV-1, HIV-2, SIV, or FIV CXCR4-specific Gp 120 sequences or Nef proteins or sequences may be delivered to the mucosa or systemically. The mucosal means of application include oral, intranasal, ocular, intravaginal, rectal, and/or intraurethral administration in liquid or particulate form.

Methods and compositions that utilize transcriptome sequencing data in machine learning-based classification

Provided herein are methods and systems for producing a modified biological dataset by flagging or removing a nucleic acid sequence from the biological dataset that is assigned a noise-call to produce the modified biological dataset. The noise-call may be based on comparing a gene expression level, sequence information, or a combination thereof with a nucleic acid sequence of a control sample.

Wavelength alignment method and device, and optical network system

A multi-functional shoe sole

一種多功能鞋底，其包含：一鞋大底、一支撐單元、一鞋外底以及發光單元，透過鞋大底底部之中空容室提供支撐單元的組裝，且該鞋外底另對應中空容室設有若干緩衝凸部，俾能利用緩衝凸部以及支撐單元之氣囊達到吸震、緩衝的效果，另提供鞋底側邊之支撐強度，藉以達到調整個人走路型態或是姿勢，又配合設有一發光單元組入鞋大底上方，使得中空容室及支撐單元還能呈現出光線色彩，增添鞋底之視覺效果，藉此俾能構成一種多功能鞋底結構。

Fan

A fan includes an impeller comprising a hub and a plurality of blades, and a housing receiving the impeller and comprising a first frame having a side wall and an inlet, and a second frame having a side wall and an outlet, wherein an inner surface on a periphery of the inlet is a smooth curved surface. The first or second frame has at least one side hole disposed at the side wall of the first or second frame.

Light-emitting device and manufacturing method thereof

A light-emitting device comprises a substrate having an top surface; a first semiconductor stack comprising a first upper surface and a first side wall, wherein the first semiconductor stack is on the top surface and exposes an exposing portion of the top surface; a second semiconductor stack comprising a second side wall, wherein the second semiconductor stack is on the first upper surface and exposes an exposing portion of the first upper surface; wherein the first side wall and the exposing portion of the top surface form an acute angle α between thereof, and the second side wall and the exposing portion of the first upper surface form an obtuse angle β between thereof.

System for entity and evidence-guided relation prediction and method of using the same

System and method multitask prediction. The system include a computing device. The computing device has a processer and a storage device storing computer executable code. The computer executable code is configured to: provide a head entity and a document containing the head entity; process the head entity and the document by a language model to obtain head extraction corresponding to the head entity, tail extractions corresponding to tail entities in the document, and sentence extraction corresponding to sentences in the document; predict a head-tail relation between the head extraction and the tail extractions using a first bilinear layer; combine the sentence extraction and a relation vector corresponding to the predicted head-tail relation using a second bilinear layer to obtain a sentence-relation combination; and predict an evidence sentence supporting the head-tail relation using a third bilinear layer based on the sentence-relation combination and attention extracted from the language model.

Stateless NAT44

An apparatus comprising a memory, and a processor coupled to the memory and configured to receive a mapping rule that associates a downstream internal Internet Protocol version four (IPv4) address prefix to an upstream external IPv4 address prefix, receive a first IPv4 packet from an upstream network node with a destination address field comprising an external IPv4 address comprising the external prefix, and perform a first network address translation IPv4 to IPv4 (NAT44) process by replacing the external IPv4 address in the first IPv4 packet's destination address field with an internal IPv4 address based on the mapping rule, wherein the internal IPv4 address comprises the internal prefix and a port set identifier (ID) associated with set of destination ports at a downstream node assigned to receive the first IPv4 packet.

Storable intravenous drip hanging rack

Process for the manufacture of substituted 2-cyano cinnamic esters

The invention relates to an improved process for the manufacture of substituted 2-cyanocinnamic esters. This novel economical process provides products in high purity and yields.

Droplet assay system

Subrounded ultrasonic ablation catheter

Methods for Identifying DNA Copy Number Changes

Methods of identifying allele-specific changes in genomic DNA copy number are disclosed. Methods for identifying homozygous deletions and genetic amplifications are disclosed. An array of probes designed to detect presence or absence of a plurality of different sequences is also disclosed. The probes are designed to hybridize to sequences that are predicted to be present in a reduced complexity sample. The methods may be used to detect copy number changes in cancerous tissue compared to normal tissue. The methods may be used to diagnose cancer and other diseases associated with chromosomal anomalies.

Controller for filtering digital video broadcasting sub-channel

End-to-end structure-aware convolutional networks for knowledge base completion

A method for knowledge base completion includes encoding a knowledge base comprising entities and relations between the entities into embeddings for the entities and embeddings for the relations. The embeddings for the entities are encoded based on a Graph Convolutional Network (GCN) with different weights for at least some different types of the relations, which GCN is called a Weighted GCN (WGCN). The method further includes decoding the embeddings by a convolutional network for relation prediction. The convolutional network is configured to apply one dimensional (1D) convolutional filters on the embeddings, which convolutional network is called Conv-TransE. The method further includes at least partially complete the knowledge base based on the relation prediction.

UMORZYTOTOXIZITÄT

Lithium salts of n-substituted glycine compounds and uses thereof

The present invention relates to a composition comprising a lithium salt of an N-substituted glycine compound and a carrier, wherein the lithium salt of the N-substituted glycine compound is of Formula (I) in which R1, R2, and R3 each are independently hydrogen, alkyl, alkenyl, alkynyl, aralkyl, carbocyclyl, aryl, or heteroaryl, or one of R1, R2, and R3 is absent. Also provided in the present invention is a method of mitigating at least one symptom of a neuropsychiatric disorder, comprising administering to a subject in need thereof the lithium salt of an N-substituted glycine compound of Formula (I).

Automatic blockage judging device for gas pipeline filtering separator

本实用新型公开了一种输气管道过滤分离器自动判堵装置，包括：第一汇管、第二汇管及两者之间的两条支路主管；一条支路主管上依次设第一阀门、第一压力表、第一旋风分离器、第一过滤分离器、第二压力表、第一流量变送器和第一电动阀门，第一差压变送器装于第一过滤分离器上；另一条支路主管上依次设第四阀门、第三压力表、第二旋风分离器、第二过滤分离器、第四压力表、第二流量变送器和第二电动阀门，第二差压变送器装于第二旋风分离器上；差压变送器、流量变送器、电动阀门均与控制系统相连。本实用新型的有益效果：能实时监测输气管道过滤分离器是否堵塞，报警速度及时、准确率高，提高了输气管道的运行效率，降低了能源损耗。

Data transmission method and virtual switch

Image subregion querying using color correlograms

A color correlogram (110) is a representation expressing the spatial correlation of color and distance between pixels in a stored image. The color correlogram may be used to distinguish objects in an image as well as between images in a plurality of images. By intersecting a color correlogram of an image object (115) with correlograms of images to be searched (100), those images which contain the objects are identified by the intersection correlogram (125).

Wafer cleaning apparatus and method

The present disclosure relates to an apparatus for wafer cleaning. The apparatus includes an enclosure made of a noncombustible material, a wafer holder, a cleaning nozzle, at least one sensor, and an exhaust unit. The wafer holder can hold and heat a wafer. The cleaning nozzle can supply a flow of a cleaning fluid onto a surface of the wafer. The at least one sensor can detect attributes of the wafer. The exhaust unit can expel a vapor generated by the cleaning fluid in the enclosure. The exhaust unit can include a rinse nozzle to rinse the vapor passing through the exhaust unit with a mist.

Adapter module for combined electrical connector and electrical connector

Methods and systems for detecting usual interstitial pneumonia

The present disclosure provides systems, methods, and classifiers for differentiating between samples as usual interstitial pneumonia (UIP) or non-UIP.

Use of hasf as a protective agent against ischemic tissue damage

A method of inducing a protective response against ischemic tissue damage is carried out by administering to subject a composition comprising an HASF polypeptide. The composition is administered prior to an ischemic event such as myocardial infarction to reduce tissue damage associated with such an event.

Semiconductor structure with doped via plug and method for forming the same

A semiconductor structure and a method for forming the same are provided. The semiconductor structure includes a gate structure, a source/drain structure, a first contact plug and a first via plug. The gate structure is positioned over a fin structure. The source/drain structure is positioned in the fin structure and adjacent to the gate structure. The first contact plug is positioned over the source/drain structure. The first via plug is positioned over the first contact plug. The first via plug includes a first group IV element.

Enriched antigen-specific t-cells, and related therapeutic and prophylactic compositions and methods

T-cell responses are initiated via contact with MHC/peptide complexes on antigen presenting cells (APCs). The fate of these complexes, however, is unknown. Here, using live APCs expressing MHC class I molecules fused with green-fluorescent protein, we show that peptide-specific T-cell/APC interaction induces clusters of MHC I molecules to congregate within minutes at the contact site; thereafter, these MHC I clusters are acquired by T-cells in small aggregates. We further demonstrate that acquisition of MHC I by T-cells correlates with TCR down regulation and the APC-derived MHC I molecules are endocytosed and degrated by T-cells. These data suggest a novel mechanism by which TCR recognition of MHC/peptide complexes can be curtailed by internalization of MHC molecules by T-cells.

Use of lithium benzoate for treating central nervous system disorders

Methods for treating central nervous system (CNS) disorders or attenuating pain with a lithium benzoate compound.

Fixing structure of blocking mask

Methods and devices for integrated tandem solar module fabrication

The present disclosure may provide methods and devices for tandem perovskite solar modules. The perovskite solar module may comprise a plurality of perovskite solar cells configured to match a voltage output of another solar module. The present disclosure may provide mixed composition perovskite layers. Solar cells fabricated using the mixed composition perovskite layers may demonstrate improved performance and stability.

System and method for relation extraction with adaptive thresholding and localized context pooling

System and method for relation extraction using adaptive thresholding and localized context pooling (ATLOP) are provided. The system includes a computing device, the computing device has a processer and a storage device storing computer executable code. The computer executable code is configured to provide a document; embed entities in the document into embedding vectors; and predict relations between a pair of entities in the document using their embedding vectors. The relation prediction is performed based on an improved language model. Each relation has an adaptive threshold, and the relation between the pair of entities is determined to exist when a logit of the relation between the pair of entities is greater than a logit function of the corresponding adaptive threshold.

Product defect detection

Embodiments of the present invention facilitate product defect detection. A computer-implemented method comprises: receiving, by a device operatively coupled to one or more processors, a template image of a normal product; generating, by the device, one or more geometric training parameters for transforming the template image; and transforming, by the device, the template image using the one or more geometric training parameters to generate a transformed image for training a data model, wherein the trained data model being used for aligning the template image and an image under inspection of a product.

Methods and systems for detecting usual interstitial pneumonia

The present disclosure provides systems, methods, and classifiers for differentiating between samples as usual interstitial pneumonia (UIP) or non-UIP.

A Silicon Chip Edge Protection Device with Collision Protection

Connector capable of reducing contact resistance of electric energy meter and good in conductivity

本实用新型公开了一种减小电能表接触电阻且导电性能良好的连接头，包括设置有开口的中空柱状壳体，所述中空柱状壳体内设置有圆柱形限位柱和若干根极细铜丝。本实用新型将中空柱状壳体安装在标准电能表的接线端子内，中空柱状壳体内设置有经过表面处理的极细铜丝，降低压接式检定台上顶针插头与安装式标准电能表的接线端子之间的接触电阻，并且减小在大电流条件下的温升。通过工具将顶针插头压入中空柱状壳体内并与极细铜丝充分接触，实现了导电性能的增强，并有效地降低了接触电阻和温升，并且同时本实用新型具有结构简单、易实现和拆卸简便的优点。

Connector

Connector manufacturing method and connector

Multi-coloured crosswalk sign with distinctive 3d vision

This design is a new multi-colored crosswalk sign with distinctive 3D vision. It belongs to road traffic sign field and includes crosswalk sign, crosswalk lane line with two trapezoids added to both ends of the white rectangle and parallel elongate trapezoids designed on both sides of the white rectangle. The trapezoids at both ends and the parallel elongate trapezoids on both sides are in different colors so that the crosswalk sign takes the appearance of distinctive 3D vision, which reminds pedestrians and drivers to be more careful.

Compositions and methods for treating aging and age-related diseases and symptoms

Frame assembly structure of doll catching machine

Tumor cytotoxicity induced by modulators of the cxcr4 receptor

The present invention provides a means of selectively killing epithelial cell carcinomas by administering a CXCR4-specific sequence of the Gp120 protein or Nef proteins or the proteins themselves (the modulators) such as that found in strains HIV-1, HIV-2, SIV, or FIV CXCR4-specific Gp 120 sequences or Nef proteins or sequences may be delivered to the mucosa or systemically. The mucosal means of application include oral, intranasal, ocular, intravaginal, rectal, and/or intraurethral administration in liquid or particulate form.

Optical transmitter, wavelength alignment method, and passive optical network system

Embodiments of the present invention disclose an optical transmitter, a 10 G-DML, an MPD 1 , an MPD 2 , a collimation lens, and a narrowband optical filter are disposed in a TO to achieve monitoring of an optical power, received optical powers are monitored by using the MPD 1 and the MPD 2 , the detected optical powers are output to a wavelength locking monitoring circuit by using a TO pin, variations, which are detected by the wavelength locking monitoring circuit, of the optical power and a variation of a wavelength locking factor K0 are separately compared with corresponding thresholds, and a comparison result are sent to a wavelength locking control circuit, to enable the wavelength locking control circuit to adjust, according to the comparison result and by using the TO pin, a temperature of a TEC to perform wavelength alignment.

Process for making multi-gate transistors and resulting structures

In a gate last metal gate process for forming a transistor, a dielectric layer is formed over an intermediate transistor structure, the intermediate structure including a dummy gate electrode, typically formed of polysilicon. Various processes, such as patterning the polysilicon, planarizing top layers of the structure, and the like can remove top portions of the dielectric layer, which can result in decreased control of gate height when a metal gate is formed in place of the dummy gate electrode, decreased control of fin height for finFETs, and the like. Increasing the resistance of the dielectric layer to attack from these processes, such as by implanting silicon or the like into the dielectric layer before such other processes are performed, results in less removal of the top surface, and hence improved control of the resulting structure dimensions and performance.

Digital/analog TV and audio media storage device

Tilt support structure

A tilt support structure is disclosed. The structure comprises a force exerted unit and a restriction unit, characterized in that the cross section of the end portion of the force exerted unit is larger than that of the middle section and the force exerted unit is mounted into the restriction unit, the restriction unit includes a single or a plurality of sleeves and in combination with concrete, cement slurry or enhanced steel beam or steel plate to form an external frame to restrict the main force exerted unit so as to prevent damage as a result of compression and the structure is stable under compression or pulling.

Process for the manufacture of substituted 2-cyano cinnamic esters

Substrate inspection transport method and device

Timer protection switch

Anaerobic ammoxidation synergistic nitrogen removal process device of municipal sewage main and side streams and application method thereof

Provided are an anaerobic ammoxidation synergistic nitrogen removal process device of municipal sewage main and side streams and an application method thereof, comprising a municipal sewage raw water tank (1), a biological reaction pool (2), a secondary sedimentation pool (3), a sludge digestion solution raw water tank (4) and a sludge digestion solution AOB strengthening pool (5); wherein, the municipal sewage raw water tank (1) is connected with a water inlet valve (2.2) of the biological reaction pool (2) through a water inlet pump (2.1) of the biological reaction pool (2); the biological reaction pool (2) is connected with the secondary sedimentation pool (3) through a secondary sedimentation pool connection pipe (3.3); the sludge digestion solution raw water tank (4) is connected with a water outlet valve (4.1) of the sludge digestion solution raw water tank (4) through a water inlet pump (4.2) of the sludge digestion solution raw water tank (4); the sludge digestion solution AOB strengthening pool (5) is connected with an anaerobic ammoxidation region compartment of the biological reaction pool through a sludge-water mixture reflux pipe (5.8) and a sludge-water mixture reflux pump (5.11). It has the advantages of reasonability in structure design, convenience in operation, low running and maintenance cost, relatively low energy consumption, no need of an additional carbon source and the like, it can realize that short distance nitrification of municipal sewage is more stable, and it is high in low-temperature, water quantity and water quality shock resistance and can further increase volumetric load at the same time.

Controlling in-vehicle air quality

A method to train a machine learning model for in-vehicle air quality control in a knowledge-based system, executed by one or more computer processors, includes collecting data related to in-vehicle air quality from a plurality of probe cars where the data is collected by various on-board systems in each probe car. The method includes correlating the data related to in-vehicle air quality from each probe car with air quality measurements from each probe car, where the correlation is used to update the machine learning model. The method includes determining a situation when an in-vehicle air quality measurement of the air quality measurements is above a pre-determined in-vehicle air quality level and determining instructions for actions by one or more of the one or more on-board systems in each of the probe cars to maintain an in-vehicle air quality level at or below the pre-determined in-vehicle air quality level.