Mobile Terminal and Power-Saving Method and Device for Same

The present invention provides a power-saving method for a mobile terminal, comprising the steps, after setting the mobile terminal to be in a data service power-saving state, monitoring, by the mobile terminal, a data service in accordance with a monitoring strategy for the data service power-saving state, and triggering a data service power-saving operation when a triggering condition set in the monitoring strategy is met. The present invention further provides a power-saving apparatus arranged within a mobile terminal, comprising a monitoring unit and an executing unit, wherein the monitoring unit is configured to monitor data services of the mobile terminal in accordance with a preset monitoring strategy, and send a power-saving command to the executing unit when a data service power-saving strategy is met. The present invention further provides a mobile terminal comprising the power-saving apparatus. As a result, the mobile can rapidly enter the data service power-saving mode according to the monitoring strategy, reduce unnecessary power consumption, and prolong the service time for the mobile terminal.

Method and Device for Data Transmission

An embodiment of the present invention provides a method and apparatus for data transmission, wherein the method comprises: establishing a buffer for TCP/IP data packets, and the TCP/IP data packets including TCP payloads and TCP ACKs; adjusting a queue of the buffered TCP/IP data in accordance with header information of the TCP/IP data packets; and transmitting sequentially the buffered TCP/IP data packets being adjusted. According to the embodiments of the present invention, the IP data packets of TCP ACKs transmitted by the receiving side are processed, so that the amount of the TCP ACK responses is significantly reduced and the IP data packets of TCP ACKs are transmitted with priority, thereby the round-trip time delay for data transmitting can be reduced, and the data transmission efficiency can be improved. 1. A method for data transmission , comprising:establishing a First In First Out (FIFO) buffer for Transmission Control Protocol/Internet Protocol (TCP/IP) data packets, and receiving and buffering the TCP/IP data packets to be transmitted, wherein the TCP/IP data packets include TCP payload data packets and TCP acknowledgement information (TCP ACK);adjusting a queue of the buffered TCP/IP data packets in accordance with header information of the TCP/IP data packets; andtransmitting sequentially the buffered TCP/IP data packets in the adjusted queue.2. The method for data transmission according to claim 1 , wherein the adjusting the queue of the buffered TCP/IP data packets in accordance with the header information of the TCP/IP data packets comprises: when there are two TCP ACKs having same source and destination IP addresses claim 1 , same TCP source port number and same destination port number claim 1 , but different acknowledgement numbers in the buffer claim 1 , retaining one of the two TCP ACKs that is most recently received and deleting the other TCP ACK.3. The method for data transmission according to claim 2 , wherein the adjusting the queue of the ...

Two-dimensional (2D) bismuth nanocomposite, and preparation method and use thereof

The disclosure relates to a two-dimensional (2D) bismuth nanocomposite, and a preparation method and use thereof, and belongs to the field of nanobiotechnology. The 2D bismuth nanocomposite of the disclosure is an ultra-thin bismuth nanosheet that is loaded with platinum nanoparticles and modified with indocyanine green (ICG) and surface targeting polypeptide Ang-2. The 2D bismuth nanocomposite Bi@Pt/ICG-Ang2 of the disclosure can not only realize the targeted photothermal and photodynamic combination therapy for tumors, but also realize the dual-mode imaging combining CT and fluorescence imaging.

Radio link monitoring and cell search techniques for high movement speeds

This disclosure relates to techniques for performing radio link monitoring and cell searching when moving at high speeds. A movement speed of a wireless device may be determined. When performing a cell search, the manner of the cell search may depend on the movement speed of the wireless device, potentially including cells that are associated with high movement speed being more highly prioritized when the wireless device is determined to be at a higher movement speed than when the wireless device is determined to be at a lower movement speed.

Cooling fin assembly

A cooling fin assembly ( 10 ) includes a plurality of cooling fins ( 10 a) joined together. Each of the cooling fins includes a main body ( 11 a) forming four engaging members ( 14 a) at four corners thereof respectively. Each of the engaging members includes a roll piece ( 15 a) with an elongated hole ( 16 a) defined therein and a connecting piece ( 17 a) with an engaging piece ( 18 a) extending therefrom. In assembly of the cooling fins, the engaging pieces of each of the cooling fins engage in the corresponding holes of the roll pieces of an adjacent cooling fin to thereby fasten and join the cooling fins with one another.

Cold-rolled high-strength steel plate having excellent phosphating performance and formability and manufacturing method therefor

A cold-rolled high-strength steel plate having excellent phosphating performance and formability and a manufacturing method therefor. The chemical composition of the steel plate is, in percentage by weight, C 0.01 - 0.20 %, Si 1.50 - 2.50 %, Mn 1.50 - 2.50 %, P≤ 0.02 %, S≤ 0.02 %, Al 0.03 - 0.06 %, N≤ 0.01 %, the remainder being Fe and impurities. The surface layer of the steel plate has an inner oxide layer with a thickness of 1 - 5 μm, and there is no enrichment of Si and Mn on the surface of the steel plate. The steel plate has tensile strength of ≥ 980 MPa and an elongation of ≥ 20 %. The structure at the room temperature contains retained austenite, ferrite, and martensite and/or bainite.

Creating virtual machine groups based on request

A method for creating a virtual machine includes: receiving a virtual machine creation request to create a plurality of virtual machines; dividing the plurality of virtual machines into a plurality of virtual machine groups; determining a home physical rack for each virtual machine group, where one virtual machine group corresponds to one home physical rack; and creating each virtual machine group on the home physical rack of each virtual machine group. Because each virtual machine group is created on a home physical rack to which each virtual machine group belongs, each virtual machine group is equivalent to one physical rack.

Creating virtual machine groups based on request

A method for creating a virtual machine includes: receiving a virtual machine creation request to create a plurality of virtual machines; dividing the plurality of virtual machines into a plurality of virtual machine groups; determining a home physical rack for each virtual machine group, where one virtual machine group corresponds to one home physical rack; and creating each virtual machine group on the home physical rack of each virtual machine group. Because each virtual machine group is created on a home physical rack to which each virtual machine group belongs, each virtual machine group is equivalent to one physical rack.

Heat sink assembly

A heat sink assembly includes a heat sink (10), a fan holder (20) mounted on the heat sink and a fan (30) carried by the fan holder. The heat sink defines a slot (148) in a top thereof. The fan holder comprises flap (260) downwardly extending to engage in the slot, and a fastening lug (28) secured to a recessed portion (122) of a top surface of a base (12) of the heat sink. The fastening lug extending from a baffle (24) which fittingly engages with a raised portion (124) of the top surface of the base adjacent to the recessed portion.

Heat sink

A heat sink ( 10 ) includes a plurality of fins ( 12 ) joined with each other. In one embodiment, each fin includes a main body ( 13 ) with an elongated flange ( 14 ) and two shortened flanges ( 16 ) extending from each of two opposite sides thereof. The shortened flanges extend from the body in an opposite direction to the elongated flange with the elongated flange located therebetween. The elongated flange ( 14 ) defines two holes ( 142 ) at respective opposite sides thereof and each shortened flange ( 16 ) provides an engaging piece ( 164 ) in alignment with one hole of the elongated flange. The engaging pieces of one fin engage in corresponding holes of an adjacent fin to thereby combine the fins together.

LOW POWER DATA COMMUNICATIONS

Techniques for low power voice communications include determining a time between an arrival of data for uplink transmission by a device and a scheduling request (SR) occasion, the SR occasion occurring after the arrival of the data and within an on duration of a discontinuous reception (DRX) cycle, and delaying transmission of a SR by the device during a time period that begins at the arrival of the data for uplink transmission and continues for the determined time.

Heat sink assembly

A heat sink assembly includes a heat sink ( 10 ), a fan holder ( 20 ) mounted on the heat sink and a fan ( 30 ) carried by the fan holder. The heat sink defines a slot ( 148 ) in a top thereof. The fan holder comprises flap ( 260 ) downwardly extending to engage in the slot, and a fastening lug ( 28 ) secured to a recessed portion ( 122 ) of a top surface of a base ( 12 ) of the heat sink. The fastening lug extending from a baffle ( 24 ) which fittingly engages with a raised portion ( 124 ) of the top surface of the base adjacent to the recessed portion.

HEAT DISSIPATION DEVICE WITH A HEAT PIPE

A heat dissipation device includes a seat and a base having a first face and a second face opposite to the first face and thermally contacting the seat. A plurality of fins extends from the first face of the base. Two heat pipes are thermally arranged on the second face of the base. Each of the two heat pipes is bent and has a section sandwiched between the base and the seat, and another section thereof stretching along the base from said section to a portion of the base in no attachment with the seat.

Method, apparatus, and artificial intelligence editor for implementing artificial intelligence behavior

Methods, apparatus and artificial intelligence (AI) editors for implementing an AI behavior are provided herein. In an exemplary method, an AI behavior configuration file can be obtained. The AI behavior configuration file can be configured using at least one preset component, and the AI behavior configuration file matches logic of a preset AI behavior. It can be tested whether a result of running the AI behavior configuration file reaches a preset effect. When the result of running the AI behavior configuration file reaches the preset effect, the preset AI behavior can be implemented according to the AI behavior configuration file.

IO Bandwidth Control Method, IO Access Request Processing Method, Apparatus, and System

An input output (IO) bandwidth control method, an IO access request processing method, an apparatus, and a system relate to the field of storage technologies, where the IO bandwidth control method, executed by a name node, includes determining an IO bandwidth of each data node in at least one data node and an IO bandwidth of a first tenant, and instructing the at least one data node to allocate the at least one IO bandwidth to the first tenant based on the IO bandwidth of each data node and the IO bandwidth of the first tenant, where the at least one IO bandwidth is in a one-to-one correspondence with the at least one data node, and each IO bandwidth in the at least one IO bandwidth is greater than 0 and is less than or equal to an IO bandwidth of a corresponding data node. 1. An input output (IO) bandwidth control method , applied to a distributed file system comprising a name node and at least one data node , wherein the method comprises:determining, by the name node, an IO bandwidth of each data node in the at least one data node;determining, by the name node, an IO bandwidth of a first tenant; andinstructing, by the name node based on the IO bandwidth of each data node in the at least one data node and the IO bandwidth of the first tenant, the at least one data node to allocate at least one IO bandwidth to the first tenant,wherein the at least one IO bandwidth is in a one-to-one correspondence with the at least one data node,wherein each IO bandwidth in the at least one IO bandwidth is less than or equal to an IO bandwidth of a corresponding data node, andwherein each IO bandwidth in the at least one IO bandwidth is greater than zero.2. The method according to claim 1 , wherein the at least one data node comprises a first data node claim 1 , wherein an IO bandwidth allocated by the first data node to the first tenant according to an instruction of the name node is a first IO bandwidth claim 1 , wherein the first IO bandwidth is an IO bandwidth in the at least ...

High-formability and super-strength cold-rolled steel sheet

A high-formability and super-strength cold-rolled steel sheet and a manufacturing method thereof. The weight percentage of its components is: C 0.15-0.25%, Si 1.00-2.00%, Mn 1.50-3.00%, P≤0.015%, S≤0.012%, Al 0.03-0.06%, N≤0.008%, and the rest are Fe and inevitable impurities. The manufacturing method comprises the following steps: 1) smelting and casting; 2) heating to 1170˜1230° C. and performing thermal insulation; 3) performing hot rolling, the finish rolling temperature being 880±30° C., and coiling at 550˜650° C.; and 4) performing acid washing, cold rolling, and annealing, the cold rolling reduction being 40-60%, annealing at 860-920° C., and performing slow cooling to 690-750° C. with the cooling rate of 3˜10° C./s; performing rapid cooling at 240˜320° C., with the cooling speed ≥50° C./s, then heating to 360˜460° C., and performing thermal insulation for 100˜500 s to cool to the room temperature at last. Finally, a high-formability, low-rebound property and super-strength cold-rolled ...

Information Determining Method and Apparatus

An information determining method and apparatus are provided. The method includes: estimating an association relationship between a feature vector and to-be-predicted attribute information of a unlabeled sample; decomposing the association relationship into N sub-association relationships in a one-to-one correspondence to N fields, and a feature vector of each sample into feature subvectors in a one-to-one correspondence to the N fields; obtaining a first value obtained by substituting a feature subvector of each labeled sample into a corresponding sub-association relationship; calculating, based on public attribute information, a sum of first values obtained in the N fields for a same user to obtain estimated attribute information; determining the association relationship based on estimated attribute information of all labeled samples and known attribute information corresponding to the estimated attribute information; and determining the to-be-predicted attribute information based on ...

Method, system and apparatus for creating virtual machine

A method, a system, and an apparatus for creating a virtual machine. The method includes receiving a virtual machine creation request to create a plurality of virtual machines; dividing the plurality of virtual machines into a plurality of virtual machine groups; determining a home physical rack for each virtual machine group, where one virtual machine group corresponds to one home physical rack; and creating each virtual machine group on the home physical rack of each virtual machine group. Because each virtual machine group is created on a home physical rack to which each virtual machine group belongs, each virtual machine group is equivalent to one physical rack.

Cold-rolled high-strength steel plate having excellent phosphating performance and formability and manufacturing method therefor

A cold-rolled steel plate (1) and a manufacturing method therefor. The chemical composition of the steel plate (1) in percentage by weight is: C 0.15-0.25%, Si 1.50-2.50%, Mn 2.00-3.00%, P≤0.02%, S≤0.01%, Al 0.03-0.06%, N≤0.01%, with the balance being Fe and impurities. The surface layer has an inner oxide layer (2) with a thickness of 1-5 μm, and there is no enrichment of Si or Mn on the surface. The steel plate (1) has good phosphating performance and formability, with a tensile strength of ≥1180 MPa and an elongation of ≥14%, and has a complex-phase structure of ferrite, martensite, and retained austenite, the content of the retained austenite being not lower than 5%. A dew point is at −25° C. to 10° C. in continuous annealing, such that external oxidation transitions to internal oxidation.

Cold-rolled high-strength steel having tensile strength of not less than 1500 MPA and excellent formability, and manufacturing method therefor

Provided is a cold-rolled high-strength steel having a tensile strength of not less than 1500 MPa and an excellent formability, the chemical elements thereof having the following mass percent ratios: 0.25%-0.40% of C, 1.50%-2.50% of Si, 2.0%-3.0% of Mn, 0.03%-0.06% of Al, P≤0.02%, S≤0.01%, N≤0.01% and at least one of 0.1%-1.0% of Cr and 0.1%-0.5% of Mo, with the balance being Fe and other unavoidable impurities. The microstructure of the cold-rolled high-strength steel has 5%-20% of residual austenite and 70%-90% of martensite, and the carbon concentration ratio of the residual austenite to the martensite is greater than 3.5 and less than 15. The cold-rolled high-strength steel sheet has a high strength and an excellent formability through a rational ingredient design and microstructure control.

IO bandwidth control method, IO access request processing method, apparatus, and system

An input output (IO) bandwidth control method, an IO access request processing method, an apparatus, and a system relate to the field of storage technologies, where the IO bandwidth control method, executed by a name node, includes determining an IO bandwidth of each data node in at least one data node and an IO bandwidth of a first tenant, and instructing the at least one data node to allocate the at least one IO bandwidth to the first tenant based on the IO bandwidth of each data node and the IO bandwidth of the first tenant, where the at least one IO bandwidth is in a one-to-one correspondence with the at least one data node, and each IO bandwidth in the at least one IO bandwidth is greater than 0 and is less than or equal to an IO bandwidth of a corresponding data node.

Data Storage Method and Apparatus

A data storage method and a physical server are provided. M virtual machines are deployed on a plurality of physical servers. The M virtual machines are respectively deployed as M data nodes in a distributed storage system. A metadata node in the distributed storage system receives a data storage request of a client, and determines identifiers of N virtual machines from the M virtual machines based on stored grouping information. The grouping information records a mapping relationship between a plurality of anti-affinity groups and identifiers of the M virtual machines. 1. A method , comprising:receiving, by a metadata node (MDS) in a distributed storage system, a data storage request of a client, wherein the distributed storage system comprises M data nodes, the M data nodes are deployed on M virtual machines, and M is a positive integer greater than or equal to 2;determining, by the MDS, that a quantity of storage copies of data specified in the data storage request is N, wherein N is a positive integer greater than or equal to 1;determining, by the MDS, identifiers of N virtual machines of the M virtual machines, wherein the identifiers of the N virtual machines are determined based on grouping information, a mapping relationship between a plurality of anti-affinity groups and identifiers of the M virtual machines is recorded in the grouping information, wherein the N virtual machines belong to at least one anti-affinity group of the plurality of anti-affinity groups, and wherein virtual machines in each anti-affinity group of the plurality of anti-affinity groups have anti-affinity with each other; andsending, by the MDS, response information of the data storage request to the client, wherein the response information comprises the identifiers of the N virtual machines, and the response information instructs the client to store, in the N virtual machines, N copies of the data specified in the data storage request.2. The method according to claim 1 , wherein ...

Method for implementing dual-homing

The invention discloses a method for implementing dual-homing, including: setting each one of any two core control equipment as a standby for each other, connecting a network entity belonging to one of the core control equipment with the two core control equipment through a primary link and a standby link respectively; setting the primary link connected with the core control equipment as activated, and setting the standby link connected with the core control equipment inactive; determining whether the core control equipment corresponding to the primary link is out of service, if the core control equipment corresponding to the primary link is out of service, activating the standby link; otherwise, continuously determining whether the core control equipment corresponding to the primary link is out of service. The invention also discloses another method for implementing dual-homing, by which the reliability of the network can be improved.

HYBRID HEAT DISSIPATION DEVICE

A heat dissipation device includes a plurality of first, second and third fins arranged side by side and a fan. The fins define a plurality of parallel channels therein respectively for air flowing therethrough. The fan and the channels of the first fins corporately define an enhanced airflow path which is isolated from the channels of the second and third fins so that the fan entirely impels an airflow generated by the fan to pass through the channels of the first fins. The first fins are located corresponding to a portion of a bottom surface of a base for contacting with a heat-generating electronic component.

Heat dissipation device having fan holder for attachment of a fan

A heat dissipation device includes a heat sink ( 10 ), a fan holder ( 20 ) located on the heat sink and a fan ( 30 ) mounted on the fan holder. The heat sink includes a plurality of fins ( 14 ) extending therefrom and defines two slots ( 16 ) in two opposite outmost fins thereof. The fan holder includes two brackets ( 200 ) each having a positioning rib ( 212 ) engaged in a corresponding slot of the heat sink and resisting the outmost fin to thereby mount the fan holder to the heat sink.

Heat dissipation device having louvered heat-dissipating fins

A heat dissipation device includes a base and a fin set arranged on the base. The fin set includes a plurality of spaced fins, a first end and a second end opposite to the first end. Pluralities of passages are defined between the fins and extending from the first end to the second end of the fin set. Each of the fins has a plurality of louvers defined therein and a plurality of tabs each extending along a side of each of the louvers from each of the fins. The louvers of the fins communicate with the passages between the fins. The tabs of each of the fins extend toward corresponding louvers of the adjacent fin. The passages communicate with ambient air at the first end and the second end of the fin set.

Creating virtual machine groups based on request

Embodiments of the present invention provide a method, a system, and an apparatus for creating a virtual machine. The method includes: receiving a virtual machine creation request to create a plurality of virtual machines; dividing the plurality of virtual machines into a plurality of virtual machine groups; determining a home physical rack for each virtual machine group, where one virtual machine group corresponds to one home physical rack; and creating each virtual machine group on the home physical rack of each virtual machine group. Because each virtual machine group is created on a home physical rack to which each virtual machine group belongs, each virtual machine group is equivalent to one physical rack.

Cooling fin assembly

The present invention relates to a cooling fin assembly suitable for heat sinks. In one embodiment, the cooling fin assembly (10) includes a plurality of cooling fins (10a) joined together. Each of the cooling fins includes a main body (11a) forming four engaging members (14a) at four corners thereof respectively. Each of the engaging members including a roll piece (15a) with an elongated hole (16a) defined therein and a connecting piece (17a) with an engaging piece (18a) extending therefrom. In assembly of the cooling fins, the engaging pieces of each of the cooling fins engage in the corresponding holes of the roll pieces of an adjacent cooling fin to thereby fasten and join the cooling fins with one another.

Heat pipe type heat dissipation device

A heat pipe type heat dissipation device for an electronic component comprises a base plate, a cover plate spaced from the base plate, a plurality of parallel fins extending between the base plate and the cover plate and connecting with them. The base plate, the cover plate and each two adjacent fins collectively define a unitary air passage. The base plate has a protuberant portion, which has a convex surface facing towards the cover plate and has a thickness getting small from the middle to two sides in a direction parallel to the fins. The cover plate also has a protuberant portion similar to the protuberant portion of the base plate. A heat pipe connects the protuberant portions of the cover plate and the base plate.

Method, System and Apparatus for Creating Virtual Machine

A method for creating a virtual machine includes: receiving a virtual machine creation request to create a plurality of virtual machines; dividing the plurality of virtual machines into a plurality of virtual machine groups; determining a home physical rack for each virtual machine group, where one virtual machine group corresponds to one home physical rack; and creating each virtual machine group on the home physical rack of each virtual machine group. Because each virtual machine group is created on a home physical rack to which each virtual machine group belongs, each virtual machine group is equivalent to one physical rack. 1. A method for creating a virtual machine and comprising:receiving one or more creation requests;creating one or more first virtual machines of a first virtual machine group on one or more first physical racks based on the one or more creation requests; andcreating one or more second virtual machines of a second virtual machine group on one or more second physical racks based on the one or more creation requests,wherein the one or more first physical racks and the one or more second physical racks are different.2. The method of claim 1 , wherein the one or more creation requests comprise a first creation request and a second creation request claim 1 , and wherein the method further comprises:further creating the one or more first virtual machines using the first creation request; andfurther creating the one or more second virtual machines using the second creation request.3. The method of claim 1 , further comprising:further creating the one or more first virtual machines for a distributed application; andfurther creating the one or more second virtual machines for the distributed application.4. The method of claim 3 , further comprising:providing a first identifier of the first virtual machine group to the distributed application; andproviding a second identifier of the second virtual machine group to the distributed application.5. The ...

Radio Link Monitoring and Cell Search Techniques for High Movement Speeds

This disclosure relates to techniques for performing radio link monitoring and cell searching when moving at high speeds. A movement speed of a wireless device may be determined. When performing a cell search, the manner of the cell search may depend on the movement speed of the wireless device, potentially including cells that are associated with high movement speed being more highly prioritized when the wireless device is determined to be at a higher movement speed than when the wireless device is determined to be at a lower movement speed. 120-. (canceled)21. An apparatus , comprising: determine a mobility state of the wireless device;', 'perform a cell search, wherein the cell search comprises scanning a plurality of cells within communication range of the wireless device; and', 'select, as part of a reselection process, a cell of the plurality of cells, wherein, when the mobility state of the wireless device corresponds to a high speed scenario, the reselection process prioritizes selection of cells identified as high speed cells., 'at least one processor configured to cause a wireless device to22. The apparatus of claim 21 , wherein the at least one processor is further configured to cause the wireless device to:receive a system information block (SIB) from a first cell of the plurality of cells, wherein the SIB includes an indication the cell is a high speed cell; andidentify the first cell as a high speed cell in the reselection process based in the indication in the SIB.23. The apparatus of claim 22 , wherein determining the mobility state of the wireless device comprises determining the mobility state of the wireless device corresponds to a high speed scenario and wherein said selecting the cell of the plurality of cells includes selecting the first cell based on the mobility state of the wireless device corresponding to the high speed scenario.24. The apparatus of claim 21 , wherein claim 21 , as part of the reselection process claim 21 , when the ...

Transplanting method for arid region plant Haloxylon seedlings

The invention discloses a transplanting method for arid region plant Haloxylon seedlings. The method mainly comprises Haloxylon seedling selection, pruning, transplanting site preparation, excavation and transporting, and transplanting and field planting. The method is simple and easy to operate. According to the key technology, ground branches need to be pruned appropriately before transplanting, a proper amount of roots are reserved, transplanting, planting and watering are carried out simultaneously, the transplanted survival rate is high, it is ensured that Haloxylon seedlings produce new roots and sprout after being transplanted, high-quality Haloxylon seedling planting in an arid region is achieved, and the method is beneficial to popularization in production in the arid region.

Locking device for a heat sink

A locking device is for locking a heat sink to an electronic device. The locking device includes a retaining frame and a guiding member positioned on the retaining frame. The guiding member includes a seat having a base sitting on the retaining frame, a sleeve extending upwardly from the seat, and two spaced legs descending from the base of the seat to retain the guiding member to the retaining frame. A fastener is accommodated in the sleeve of the guiding member and is kept vertical to the retaining frame by the guiding member.

Heat sink for a portable computer

A heat sink ( 200 ) for a portable computer ( 100 ) includes a plurality of fins ( 210 ) located external to the portable computer, a conducting plate ( 230 ) extending into an inner space of the portable computer for absorbing heat in the portable computer, and a heat pipe ( 220 ) transferring the heat absorbed by the conducting plate to the fins. Therefore, the heat in the portable computer is removed from the inner space of the portable computer by the heat sink.

Hot dipped high manganese steel and manufacturing method therefor

A hot dipped high manganese steel and a manufacturing method therefor. The high manganese steel comprises a steel base plate and a coating on the surface of the steel base plate. The core of the steel base plate is austenite. The surface layer of the steel base plate is a ferrite fine grain layer. The ferrite fine grain layer comprises an oxide of Al. Furthermore, the steel base plate of the hot dipped high manganese steel comprises, in mass percentages, 10 to 30% of Mn element, 1 to 2% of Al element, and 0.4 to 0.8% of C element. The manufacturing method comprises: 1) manufacturing strip steel; 2) primary annealing and acid washing; 3) secondary annealing and hot dipping.

Mobile terminal and power-saving method and device for same

The present invention provides a power-saving method for a mobile terminal, comprising the steps, after setting the mobile terminal to be in a data service power-saving state, monitoring, by the mobile terminal, a data service in accordance with a monitoring strategy for the data service power-saving state, and triggering a data service power-saving operation when a triggering condition set in the monitoring strategy is met. The present invention further provides a power-saving apparatus arranged within a mobile terminal, comprising a monitoring unit and an executing unit, wherein the monitoring unit is configured to monitor data services of the mobile terminal in accordance with a preset monitoring strategy, and send a power-saving command to the executing unit when a data service power-saving strategy is met. The present invention further provides a mobile terminal comprising the power-saving apparatus. As a result, the mobile can rapidly enter the data service power-saving mode according ...

HEAT SINK FOR A PORTABLE COMPUTER

A heat sink (200) for a portable computer (100) includes a plurality of fins (210) located external to the portable computer, a conducting plate (230) extending into an inner space of the portable computer for absorbing heat in the portable computer, and a heat pipe (220) transferring the heat absorbed by the conducting plate to the fins. Therefore, the heat in the portable computer is removed from the inner space of the portable computer by the heat sink.

RADIO ACCESS FALLBACK FOR INTERNET PROTOCOL MULTIMEDIA SUBSYSTEM REGISTRATION

The present application relates to devices and components including apparatus, systems, and methods for IMS registration in wireless networks.

Heat sink fastening assembly

A fastening assembly is for securing a heat sink to a heat generating electronic device located on a printed circuit board. The fastening assembly includes a first element and a second element slidably received in the first element. The first element includes a pressing portion, a plurality of outer flexible portions located below the pressing portion and a plurality of inner flexible portions integrally extending inwards from the outer flexible portions, respectively. The pressing portion of the first element presses downwardly the heat sink toward the electronic device. The outer flexible portions of the first element abut upwardly against the printed circuit board. The second element is capable of acting on the inner flexible portions of the first element to motivate the outer flexible portions to release their abutment from the printed circuit board.

Method, System and Apparatus for Creating Virtual Machine

A method, a system, and an apparatus for creating a virtual machine. The method includes receiving a virtual machine creation request to create a plurality of virtual machines; dividing the plurality of virtual machines into a plurality of virtual machine groups; determining a home physical rack for each virtual machine group, where one virtual machine group corresponds to one home physical rack; and creating each virtual machine group on the home physical rack of each virtual machine group. Because each virtual machine group is created on a home physical rack to which each virtual machine group belongs, each virtual machine group is equivalent to one physical rack. 1. A method for creating a virtual machine comprising:receiving a virtual machine creation request, wherein the virtual machine creation request is used to create a plurality of virtual machines for a distributed application;dividing the plurality of virtual machines into a plurality of virtual machine groups, wherein each virtual machine group comprises at least one virtual machine;acquiring configuration information of each virtual machine group, wherein the configuration information of each virtual machine group comprises the number of virtual machines that are part of each virtual machine group and a specification of each of the virtual machines;determining a virtual machine rack attribute of the virtual machine group according to a rack awareness attribute of the distributed application, wherein the virtual machine rack attribute denotes that one virtual machine group corresponds to one home physical rack;determining one home physical rack for each virtual machine group according to the virtual machine rack attribute of the virtual machine group; andcreating each virtual machine group on the home physical rack of each virtual machine group according to the configuration information of each virtual machine group.2. The method according to claim 1 , wherein creating each virtual machine group on the ...

Superstrength cold-rolled weathering steel sheet and method of manufacturing same

The present invention discloses a superstrength cold rolled weathering steel sheet, wherein the weight percentage of the chemical elements thereof are as follows: C: 0.05˜0.16%; Mn: 1.00˜2.20%; Al: 0.02˜0.06%; Cu: 0.20˜0.40%; Cr: 0.40˜0.60%; Ti: 0.015˜0.035%; P: less than 0.03%; and C+Mn/16 is more than 0.19% and less than 0.23%; the remainders thereof being Fe and other unavoidable impurities. The present invention also discloses a method of manufacturing said superstrength cold rolled weathering steel sheet, comprising the following stages: smelting, heating and preservation, hot rolling, coiling, pickling, cold rolling, continuous annealing and skin passing. The advantages of the superstrength cold rolled weathering steel sheet and the method of manufacturing the same are: high strength, i.e., the yield strength more than 700 MPa and the tensile strength more than 1000 MPa; excellent performance of atmosphere corrosion resistance; thin so as to meet the demand of reducing the thickness ...

Data storage method and apparatus

A data storage method and a physical server are provided. M virtual machines are deployed on a plurality of physical servers. The M virtual machines are respectively deployed as M data nodes in a distributed storage system. A metadata node in the distributed storage system receives a data storage request of a client, and determines identifiers of N virtual machines from the M virtual machines based on stored grouping information. The grouping information records a mapping relationship between a plurality of anti-affinity groups and identifiers of the M virtual machines.

Heat sink

A heat sink (10) includes a plurality of fins (12) joined with each other. In one embodiment, each fin includes a main body (13) with an elongated flange (14) and two shortened flanges (16) extending from each of two opposite sides thereof. The shortened flanges extend from the body in an opposite direction to the elongated flange with the elongated flange located therebetween. The elongated flange (14) defines two holes (142) at respective opposite sides thereof and each shortened flange (16) provides an engaging piece (164) in alignment with one hole of the elongated flange. The engaging pieces of one fin engage in corresponding holes of an adjacent fin to thereby combine the fins together.

Heat sink fastening assembly

A fastening assembly is for securing a heat sink to a heat generating electronic device located on a printed circuit board. The fastening assembly includes a first element and a second element slidably received in the first element. The first element includes a pressing portion, a plurality of outer flexible portions located below the pressing portion and a plurality of inner flexible portions integrally extending inwards from the outer flexible portions, respectively. The pressing portion of the first element presses downwardly the heat sink toward the electronic device. The outer flexible portions of the first element abut upwardly against the printed circuit board. The second element is capable of acting on the inner flexible portions of the first element to motivate the outer flexible portions to release their abutment from the printed circuit board.

CLIP ASSEMBLY FOR ATTACHING A HEAT SINK TO AN ELECTRONIC DEVICE

A clip assembly includes a bolt, a sleeve, and a resilient component held between the bolt and the sleeve. The bolt includes a head formed at an end thereof, an engaging portion formed at an opposite end thereof, and an engaging structure located between the head and the engaging portion. The sleeve includes a hollow body having an engaging structure. When the bolt is inserted into the body of the sleeve along a first direction, the engaging structure of the bolt engages with the engaging structure of the sleeve to block the bolt from escaping from the sleeve along a second direction opposite to the first direction. The resilient component is adapted to exert a force on the bolt to cause the bolt to have a tendency to move along the second direction.

Hybrid heat dissipation device

A heat dissipation device includes a plurality of first, second and third fins arranged side by side and a fan. The fins define a plurality of parallel channels therein respectively for air flowing therethrough. The fan and the channels of the first fins corporately define an enhanced airflow path which is isolated from the channels of the second and third fins so that the fan entirely impels an airflow generated by the fan to pass through the channels of the first fins. The first fins are located corresponding to a portion of a bottom surface of a base for contacting with a heat-generating electronic component.

Method, apparatus, and artificial intelligence server for determining artificial intelligence behavior

According to methods, apparatus and AI servers for determining an AI behavior, a protocol-requesting command sent by an application logic server can be received. The protocol-requesting command can contain an application identifier, a notification message, and current environment data. From a plurality of preset AI systems, an AI system corresponding to the application identifier can be found. The AI system can be formed by a preset plurality of components that include one or more classifying components. From the AI system, a classifying component corresponding to the notification message can be found. The classifying component can be mounted with at least one behavior component. From the classifying component corresponding to the notification message, a behavior component matching the current environment data can be obtained. An AI behavior can be determined based on the obtained behavior component matching the current environment data.

LOCKING DEVICE FOR A HEAT SINK

A locking device is for locking a heat sink to an electronic device. The locking device includes a retaining frame and a guiding member positioned on the retaining frame. The guiding member includes a seat having a base sitting on the retaining frame, a sleeve extending upwardly from the seat, and two spaced legs descending from the base of the seat to retain the guiding member to the retaining frame. A fastener is accommodated in the sleeve of the guiding member and is kept vertical to the retaining frame by the guiding member.

Fixing apparatus for mounting a heat sink to a printed circuit board

A fixing apparatus includes a retention module ( 10 ) and a back plate ( 30 ). The retention module is attached on a printed circuit board ( 20 ), which defines a plurality of through apertures ( 22 ). The retention module comprises a plurality of posts ( 12 ) depending therefrom. Each post is hollow and aligned with a corresponding through aperture. The back plate is attached on a bottom surface of the printed circuit board, for reinforcing the printed circuit board. The back plate comprises a plurality of upwardly extending poles ( 32 ). The poles extend through the through apertures and lock inside of the posts to secure the retention module and the back plate on opposites sides of the printed circuit board.

Method, system and apparatus for creating virtual machine

A method, a system, and an apparatus for creating a virtual machine. The method includes receiving a virtual machine creation request to create a plurality of virtual machines; dividing the plurality of virtual machines into a plurality of virtual machine groups; determining a home physical rack for each virtual machine group, where one virtual machine group corresponds to one home physical rack; and creating each virtual machine group on the home physical rack of each virtual machine group. Because each virtual machine group is created on a home physical rack to which each virtual machine group belongs, each virtual machine group is equivalent to one physical rack.

COMPENSATION DATA PREDICTION

A method of predicting compensation data includes obtaining compensation data, associated with a job category, with at least one datum being associated with each of a plurality of characteristics associated with the job category, determining values of factors, associated with respective ones of the characteristics, and a base value that when used as operands of a function yield estimates of the obtained data such that relationships between the estimates and corresponding obtained compensation data satisfy at least one criterion, and using a portion of the values of factors and the base value by a computer to automatically obtain estimates of compensation data. 14-. (canceled)5. A method of predicting compensation data , comprising:determining, for each of a plurality of characteristics associated with a first job category, a training factor and a value associated with the training factor;determining a base value for the job category;identifying a function satisfying at least one criterion, the function uses the base value, and the values of the training factors to estimate compensation data; andautomatically generating, using a computer hardware system, estimated compensation data using the function, the base value, and at least a portion of the values of the training factors.6. The method of claim 5 , whereina value of a first training factor is dependent upon a value of a second training factor.7. The method of claim 5 , whereina value of a first training factor is dependent upon both a value of a second training factor and a value of a third training factor.8. The method of claim 5 , further comprising:determining, for each of a plurality of characteristics associated with a second job category, a training factor and a value associated with the training factor.9. The method of claim 8 , further comprising:determining a training factor between the first job category and the second job category and a value associated with the training factor.10. The method of claim ...

Method for implementing dual-homing

The invention discloses a method for implementing dual-homing, including: setting each one of any two core control equipment as a standby for each other, connecting a network entity belonging to one of the core control equipment with the two core control equipment through a primary link and a standby link respectively; setting the primary link connected with the core control equipment as activated, and setting the standby link connected with the core control equipment inactive; determining whether the core control equipment corresponding to the primary link is out of service, if the core control equipment corresponding to the primary link is out of service, activating the standby link; otherwise, continuously determining whether the core control equipment corresponding to the primary link is out of service. The invention also discloses another method for implementing dual-homing, by which the reliability of the network can be improved.

Stress-resistant, creep-resistant, high-temperature resistant and high-insulation sheath material for maglev train cable, and manufacturing method and use thereof

Disclosed are a stress-resistant, creep-resistant, high-temperature resistant and high-insulation sheath material for a maglev train cable, and a manufacturing method and use thereof. A multiple chemical crosslinking structure is constructed by blending a functional polyvinylsilicone grease with ultra-high molecular weight polyethylene (UHMWPE) and a ceramicized silicone rubber as a cable material matrix and using electron beam irradiation. In addition, organic/inorganic fillers in the matrix can form physical crosslinking points in the material. A physical-chemical dual crosslinking structure is constructed in the matrix, which can limit the motion and relaxation of molecular chains and improve the interaction between the insulation layer and sheath layer and refractory layers such as fillers and mica tapes to avoid the relative displacement during the laying and operation and improve the high-temperature resistance, creep resistance and stress relaxation resistance of a UHMWPE cable sheath ...

Method and device for data transmission

A method of data transmission includes establishing a buffer for TCP/IP data packets, receiving and buffering the TCP/IP data packets including TCP payloads and TCP ACKs. A queue of the buffered TCP/IP data is adjusted in accordance with header information of the TCP/IP data packets. The buffered TCP/IP data packets are transmitted sequentially. The method significantly reduces the TCP ACKs, which are transmitted with priority, thereby reducing the round-trip time delay, and improving the data transmission efficiency. An apparatus configured to perform this method is also described.

HEAT DISSIPATION DEVICE HAVING FAN HOLDER FOR ATTACHMENT OF A FAN

A heat dissipation device includes a heat sink (10), a fan holder (20) located on the heat sink and a fan (30) mounted on the fan holder. The heat sink includes a plurality of fins (14) extending therefrom and defines two slots (16) in two opposite outmost fins thereof. The fan holder includes two brackets (200) each having a positioning rib (212) engaged in a corresponding slot of the heat sink and resisting the outmost fin to thereby mount the fan holder to the heat sink.

METHOD FOR IMPLEMENTING DUAL-HOMING

The invention discloses a method for implementing dual-homing, including: setting each one of any two core control equipment as a standby for each other, connecting a network entity belonging to one of the core control equipment with the two core control equipment through a primary link and a standby link respectively; setting the primary link connected with the core control equipment as activated, and setting the standby link connected with the core control equipment inactive; determining whether the core control equipment corresponding to the primary link is out of service, if the core control equipment corresponding to the primary link is out of service, activating the standby link; otherwise, continuously determining whether the core control equipment corresponding to the primary link is out of service. The invention also discloses another method for implementing dual-homing, by which the reliability of the network can be improved.

High-formability and super-strength hot galvanizing steel plate and manufacturing method thereof

A high-formability, super-high-strength, hot-dip galvanized steel plate, the chemical composition of which comprises, based on weight percentage, C: 0.15-0.25 wt %, Si: 1.00-2.00 wt %, Mn: 1.50-3.00 wt %, P≤0.015 wt %, S≤0.012 wt %, Al: 0.03-0.06 wt %, N≤0.008 wt %, and the balance of iron and unavoidable impurities. The room temperature structure of the steel plate comprises 10-30% ferrite, 60-80% martensite and 5-15% residual austenite. The steel plate has a yield strength of 600-900 MPa, a tensile strength of 980-1200 MPa, and an elongation of 15-22%. Through an appropriate composition design, a super-high-strength, cold rolled, hot-dip galvanized steel plate is manufactured by continuous annealing, wherein no expensive alloy elements are added; instead, remarkable increase of strength along with good plasticity can be realized just by appropriate augment of Si, Mn contents in combination with suitable processes of annealing and furnace atmosphere control. In addition, the steel plate ...

SUPERSTRENGTH COLD ROLLED WEATHERING STEEL SHEET AND METHOD OF MANUFACTURING SAME

The present invention discloses a superstrength cold rolled weathering steel sheet, wherein the weight percentage of the chemical elements thereof are as follows: C: 0.05˜0.16%; Mn: 1.00˜2.20%; Al: 0.02˜0.06%; Cu: 0.20˜0.40%; Cr: 0.40˜0.60%; Ti: 0.015˜0.035%; P: less than 0.03%; and C+Mn/16 is more than 0.19% and less than 0.23%; the remainders thereof being Fe and other unavoidable impurities. The present invention also discloses a method of manufacturing said superstrength cold rolled weathering steel sheet, comprising the following stages: smelting, heating and preservation, hot rolling, coiling, pickling, cold rolling, continuous annealing and skin passing. The advantages of the superstrength cold rolled weathering steel sheet and the method of manufacturing the same are: high strength, i.e., the yield strength more than 700 MPa and the tensile strength more than 1000 MPa; excellent performance of atmosphere corrosion resistance; thin so as to meet the demand of reducing the thickness and weight thereof; good shape and surface quality. 41. The superstrength cold rolled weathering steel sheet according to claim , wherein the microstructure thereof is martensite , the volume fraction of which is more than 95%.51. The superstrength cold rolled weathering steel sheet according to claim , wherein the thickness thereof is 0.8˜1.5 mm.61. A container panel manufactured with said superstrength cold rolled weathering steel sheet according to claim .71. An automobile structural plate manufactured with said superstrength cold rolled weathering steel sheet according to claim .81. A method of manufacturing said superstrength cold rolled weathering steel sheet according to claim , wherein it comprises the following stages: smelting , heating and preservation , hot rolling , coiling , pickling , cold rolling , continuous annealing , skin passing; wherein , in the continuous annealing process , the annealing temperature is 830˜880° C. so as to enable the complete austenization , ...

Radio link monitoring and cell search techniques for high movement speeds

This disclosure relates to techniques for performing radio link monitoring and cell searching when moving at high speeds. A movement speed of a wireless device may be determined. When performing a cell search, the manner of the cell search may depend on the movement speed of the wireless device, potentially including cells that are associated with high movement speed being more highly prioritized when the wireless device is determined to be at a higher movement speed than when the wireless device is determined to be at a lower movement speed.

Radio Link Monitoring and Cell Search Techniques for High Movement Speeds

This disclosure relates to techniques for performing radio link monitoring and cell searching when moving at high speeds. A movement speed of a wireless device may be determined. When performing a cell search, the manner of the cell search may depend on the movement speed of the wireless device, potentially including cells that are associated with high movement speed being more highly prioritized when the wireless device is determined to be at a higher movement speed than when the wireless device is determined to be at a lower movement speed. 1. An apparatus , comprising: detect one or more conditions indicating that the wireless device is moving at a high speed; and', 'perform a cell search, wherein one or more frequencies associated with high movement speed are prioritized during the cell search based at least in part on detecting the one or more conditions indicating that the wireless device is moving at a high speed,', 'wherein the one or more frequencies associated with high movement speed have lower priority during a cell search when no conditions indicating that the wireless device is moving at a high speed are detected., 'a processor configured to cause a wireless device to2. The apparatus of claim 1 , wherein to detect the one or more conditions indicating that the wireless device is moving at a high speed claim 1 , the processor is further configured to cause the wireless device to:detect, camp on or attach to a serving cell; anddetermine that the serving cell is associated with high movement speed based at least in part on an indication broadcast by the serving cell.3. The apparatus of claim 2 , wherein the processor is further configured to cause the wireless device to claim 2 , at a later time:determine that the wireless device has not re-selected to, handed over to, or detected a serving cell associated with high movement speed for at least a predetermined period of time; andperform a second cell search, wherein the one or more frequencies associated ...

Method, System and Apparatus for Creating Virtual Machine

A method, a system, and an apparatus for creating a virtual machine. The method includes receiving a virtual machine creation request to create a plurality of virtual machines; dividing the plurality of virtual machines into a plurality of virtual machine groups; determining a home physical rack for each virtual machine group, where one virtual machine group corresponds to one home physical rack; and creating each virtual machine group on the home physical rack of each virtual machine group. Because each virtual machine group is created on a home physical rack to which each virtual machine group belongs, each virtual machine group is equivalent to one physical rack. 1. A method for creating a virtual machine comprising:receiving a virtual machine creation request, wherein the virtual machine creation request is used to create a plurality of virtual machines;dividing the plurality of virtual machines into a plurality of virtual machine groups, wherein each virtual machine group comprises at least one virtual machine;determining a home physical rack for each virtual machine group, wherein one virtual machine group corresponds to one home physical rack; andcreating each virtual machine group on the home physical rack of each virtual machine group.2. The method according to claim 1 , wherein creating each virtual machine group on the home physical rack of each virtual machine group comprises creating different virtual machines of each virtual machine group in different physical machines on the home physical rack.3. The method according to claim 1 , wherein determining the home physical rack for each virtual machine group comprises determining one home physical rack for each virtual machine group according to configuration information of each virtual machine group claim 1 , and wherein the configuration information of each virtual machine group comprises the number of virtual machines that are part of each virtual machine group and a specification of each of the virtual ...

Heat sink

A heat sink for dissipating heat from an electronic component comprises a heat spreader and a plurality of first fins and second fins provided thereon. The first and second fins are parallel to each other and arranged in alternating order so as to define a plurality of air passages. The first and second fins are so arranged that thinner air passages and denser fin distribution in the middle along the extension direction of the air passages and wider air passages and lower fin distribution density at two ends are provided.

HEAT PIPE TYPE HEAT DISSIPATION DEVICE

A heat pipe type heat dissipation device for an electronic component comprises a base plate, a cover plate spaced from the base plate, a plurality of parallel fins extending between the base plate and the cover plate and connecting with them. The base plate, the cover plate and each two adjacent fins collectively define a unitary air passage. The base plate has a protuberant portion, which has a convex surface facing towards the cover plate and has a thickness getting small from the middle to two sides in a direction parallel to the fins. The cover plate also has a protuberant portion similar to the protuberant portion of the base plate. A heat pipe connects the protuberant portions of the cover plate and the base plate.

PROCESS FOR THE PREPARATION OF AN OREXIN RECEPTOR ANTAGONIST

The present invention is directed to processes for preparing a pyridyl piperidine compound which is an antagonist of orexin receptors, and which is useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. 2. The process of wherein the activating agent is an acid chloride.3. The process of wherein the activating agent is trimethylacetyl chloride.4. The process of wherein the organic base is a weak organic base.5. The process of wherein the organic base is selected from 2 claim 1 ,6-lutidine claim 1 , 2 claim 1 ,4 claim 1 ,6-lutidine claim 1 , and Hunig's base.6. The process of wherein 1-propylphosphonic anhydride is present at less than a stochiometric amount.7. The process of wherein 1-propylphosphonic anhydride is present at less than 10 mol %.8. The process of wherein the process is conducted in an amide solvent or acetonitrile.9. The process of wherein the process is conducted in an amide solvent which is selected from the group consisting of: formamide claim 8 , N-methylformamide claim 8 , N claim 8 ,N-dimethylformamide claim 8 , acetamide claim 8 , N-methylacetate claim 8 , N claim 8 ,N-dimethylacetamide claim 8 , N claim 8 ,N claim 8 ,N′ claim 8 ,N′-tetramethylurea claim 8 , 2-pyrrolidone claim 8 , and N-methylpyrrolidone.10. The process of wherein the amide solvent is N claim 9 ,N-dimethylformamide.11. The process of wherein the process is conducted in acetonitrile.13. The process of wherein the aromatic solvent is tert-butylbenzene.14. The process of wherein the aromatic solvent is toluene.15. The process of wherein the aromatic solvent which additionally comprises heptane. The orexins (hypocretins) comprise two neuropeptides produced in the hypothalamus: the orexin A (OX-A) (a 33 amino acid peptide) and the orexin B (OX-B) (a 28 amino acid peptide) (Sakurai T. et al., Cell, 1998, 92, 573-585). Orexins are found to stimulate food consumption in rats suggesting a physiological role ...

DETACHABLE COVER MODULE AND CHASSIS HAVING THE SAME

A detachable cover module includes a bezel body, a button, and a sliding member. The button is pivotally connected to the bezel body. The button includes a pushing member. The sliding member includes a connecting portion and a guiding element. When the button is pressed in a first direction, the pushing member pushes the guiding element, so that the connecting portion moves from a position protruding outward from the bezel body toward a position not protruding outward from the bezel body. When the button is not pressed, the connecting portion of the sliding member is normally maintained at the position protruding outward from the bezel body. The detachable cover module is adapted to be pivotally connected to a body of a chassis to selectively expose or cover an opening of the chassis body. 1. A detachable cover module , comprising:a bezel body;a button, one end thereof being pivotally connected to the bezel body, and the button comprising a pushing member; anda sliding member comprising a connecting portion and a guiding element, when the button is pressed in a first direction, the pushing member pushing the guiding element, so that the connecting portion of the sliding member moves in a second direction from a position protruding outward from the bezel body toward a position not protruding outward from the bezel body, wherein an included angle is formed between the first direction and the second direction.2. The detachable cover module according to claim 1 , further comprising a first elastic member and a second elastic member claim 1 , wherein the button pivots between a first position and a second position claim 1 , the first elastic member has a force that normally pushes the sliding member toward a protruding position and the second elastic member has a force that normally pushes the button toward the first position.3. The detachable cover module according to claim 1 , wherein the sliding member has a rod portion claim 1 , the guiding element is fixed to the ...

PROCESS FOR MAKING BETA 3 AGONISTS AND INTERMEDIATES

The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency. 114-. (canceled)16. The process of claim 15 , wherein Ris selected from the group consisting of Calkyl claim 15 , benzyl claim 15 , and phenyl.17. The process of claim 16 , wherein Ris selected from the group consisting of methyl claim 16 , ethyl claim 16 , propyl claim 16 , butyl claim 16 , and benzyl.18. The process of claim 17 , wherein Ris methyl.19. The process of claim 15 , wherein the base is selected from the group consisting of NaOH claim 15 , LiOH claim 15 , KOH claim 15 , CsOH claim 15 , Ca(OH) claim 15 , Ba(OH) claim 15 , Mg(OH) claim 15 , KCO claim 15 , NaCO claim 15 , and CsCO.20. The process of claim 19 , wherein the base is NaOH claim 19 , LiOH claim 19 , or KOH.21. The process of claim 20 , wherein the base is NaOH.22. The process of claim 15 , wherein the hydrolysis of step (a) is carried out in the presence of a solvent.23. The process of claim 22 , wherein the solvent is selected from the group consisting of methanol claim 22 , water claim 22 , THF claim 22 , EtOH claim 22 , IPA claim 22 , α-methyl-THF claim 22 , and mixtures thereof.24. The process of claim 23 , wherein the solvent is a mixture of methanol/water claim 23 , THF/water claim 23 , EtOH/water claim 23 , IPA/water claim 23 , or α-methyl-THF/water.25. The process of claim 24 , wherein the solvent is a mixture of methanol/water.26. The process of claim 15 , wherein the hydrolysis of step (a) is carried out at 0° C. to 5° C.27. The process of claim 15 , wherein the solid of step (b) is isolated by crystallization.29. The process of claim 28 , wherein the solid of step (b) is isolated by crystallization.31. The crystalline compound of claim 30 , wherein the crystalline compound is a hydrate. This is a continuation ...

Process for Making Beta 3 Agonists and Intermediates

The present invention is directed to a process for preparing a compound of formula I-11 through multiple-step reactions: 115-. (canceled)17. The process of claim 16 , wherein in step (e) said oxidizing is carried out with an oxidizing agent in the presence of a solvent and a catalyst;{'sub': 2', '2, 'said solvent is selected from the group consisting of tetrahydrofuran (THF), methyl tert-butyl ether (MTBE), dichloromethane (CHCl), acetonitrile (MeCN), toluene and a mixture comprising two of said foregoing solvents;'}{'sub': '2', 'said oxidizing agent is selected from the group consisting of sodium hypochlorite (NaOCl), sodium chlorite (NaClO), hydrogen peroxide, pyridine sulfur trioxide, pyridinium chlorochromate (PCC), and N,N′-dicyclohexycarbodiimide (DCC); and'}said catalyst is 1-oxyl-2,2,6,6-tetramethylpiperidine (TEMPO) or a TEMPO analogue.18. The process of claim 16 , wherein said reaction between said compound I-7 and said compound A-4 in step (f) is carried out at a temperature of 20 to 40° C. and in the presence of a solvent selected from the group consisting of THF claim 16 , MTBE claim 16 , CHCl claim 16 , MeCN claim 16 , toluene and a mixture comprising two of said foregoing solvents.19. The process of claim 16 , wherein in step (g) said reducing is carried out in the presence of a catalyst and hydrogen gas; and{'sub': 2', '2, 'said catalyst is selected from the group consisting of Pd, Raney Ni, Pt, PdCl, and Pd(OH).'}20. The process of claim 16 , wherein said acid in step (h) is selected from the group consisting of HCl claim 16 , HBr claim 16 , trifluoroacetic acid (TFA) claim 16 , MeSOH claim 16 , TfOH claim 16 , HSO claim 16 , para-toluenesulfonic acid claim 16 , and RSOH claim 16 , wherein R is an alkyl claim 16 , an aryl or a substituted aryl.21. The process of claim 16 , wherein said P1 and said P2 are each independently selected from the group consisting of acyl (Ac) claim 16 , benzyl (Bn) claim 16 , t-butyloxycarbonyl (Boc) claim 16 , benzoyl ( ...

Process for Making Beta 3 Agonists and Intermediates

The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency. 114-. (canceled)16. The process of wherein the solvent is selected from the group consisting of MeOH claim 15 , EtOH claim 15 , IPA claim 15 , n-PrOH claim 15 , MeCN claim 15 , DMF claim 15 , DMAc claim 15 , THF claim 15 , EtOAc claim 15 , IPAc claim 15 , and toluene.17. The process of claim 15 , wherein the acid is selected from the group consisting of HCl claim 15 , HBr claim 15 , HI claim 15 , HNO claim 15 , HSO claim 15 , HPO claim 15 , TFA claim 15 , and MeSOH.18. The process of claim 15 , further comprising adding EDCI to the mixture of compound I-11 claim 15 , compound i-30 claim 15 , and acid.21. The method of claim 20 , further comprising adjusting the pH to from 6.5 to 7.0.22. The method of claim 20 , wherein the molar ratio of the compound of formula A-4 to the compound of formula I-7 is from about 1:1 to about 1.2:1.23. The method of claim 20 , further comprising dissolving the compound of formula A-4 in a solvent to form a solution prior to the addition of the compound of formula I-7.24. The method of claim 23 , wherein the solvent is selected from THF claim 23 , MTBE claim 23 , CHCl claim 23 , MeCN claim 23 , toluene claim 23 , and a mixture thereof.25. The method of claim 23 , further comprising adding a base to the solution prior to the addition of the compound of formula I-7.26. The method of claim 25 , wherein the base is a tertiary amine.27. The method of claim 26 , wherein the base is N claim 26 ,N-diisopropylethylamine.28. The method of claim 25 , further comprising adding a salt to the solution prior to the addition of the compound of formula I-7.29. The method of claim 28 , wherein the salt is a lithium halide.30. The method of claim 29 , wherein the salt is selected from ...

PROCESS FOR MAKING BETA 3 AGONISTS AND INTERMEDIATES

The present invention is directed to a process for preparing a compound of formula I-11 through multiple-step reactions: 115.-. (canceled)17. The process of claim 16 , wherein the reducing agent of step (a) is selected from the group consisting of LiAlH claim 16 , LiBH claim 16 , NaBH—LiBr claim 16 , and DIBAL.18. The process of claim 16 , wherein in step (b) said solvent is selected from the group consisting of tetrahydrofuran (THF) claim 16 , methyl tert-butyl ether (MTBE) claim 16 , dichloromethane (CHCl) claim 16 , acetonitrile (MeCN) claim 16 , toluene and a mixture comprising two of said foregoing solvents.19. The process of claim 16 , wherein in step (b) said oxidizing agent is selected from the group consisting of sodium hypochlorite (NaOCl) claim 16 , sodium chlorite (NaClO) claim 16 , hydrogen peroxide claim 16 , pyridine sulfur trioxide claim 16 , pyridinium chlorochromate (PCC) claim 16 , and N claim 16 ,N′-dicyclohexycarbodiimide (DCC).20. The process of claim 16 , wherein in step (b) said catalyst is 1-oxyl-2 claim 16 ,2 claim 16 ,6 claim 16 ,6-tetramethylpiperidine (TEMPO) or a TEMPO analogue.21. The process of claim 16 , wherein said reaction between said compound I-7 and said compound A-4 in step (c) is carried out at a temperature of 20 to 40° C. and in the presence of a solvent selected from the group consisting of THF claim 16 , MTBE claim 16 , CHCl claim 16 , MeCN claim 16 , toluene and a mixture comprising two of said foregoing solvents.22. The process of claim 16 , wherein said catalyst in step (d) is selected from the group consisting of Pd claim 16 , Raney Ni claim 16 , Pt claim 16 , PdCl claim 16 , and Pd(OH).23. The process of claim 16 , wherein said reducing in step (d) is carried out in the presence of hydrogen gas.24. The process of claim 16 , wherein said acid in step (e) is selected from the group consisting of HCl claim 16 , HBr claim 16 , trifluoroacetic acid (TFA) claim 16 , MeSOH claim 16 , TfOH claim 16 , HSO claim 16 , para- ...

PROCESS FOR MAKING BETA 3 AGONISTS AND INTERMEDIATES

The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency. 114-. (canceled)18. The process of claim 15 , wherein the coupling agent comprises EDC.19. The process of claim 15 , wherein the acid is HCl.20. The process of claim 15 , wherein the solvent is an aqueous solvent.21. The process of claim 15 , wherein the solvent is IPA.22. The process of claim 15 , wherein the process further comprises (b) adding aqueous ammonia to the reaction mixture of step (a) to form a slurry.23. The process of claim 22 , wherein the process further comprises (c) aging the slurry before filtration. This is a divisional application of U.S. application Ser. No. 15/057,427, filed on Mar. 1, 2016, which is a continuation application of U.S. application Ser. No. 14/354,158, filed on Apr. 25, 2014, which is a 371 National Stage Application of PCT/US12/61252, filed on Oct. 22, 2012, which claims priority from U.S. Provisional Application No. 61/552,195, filed on Oct. 27, 2011. Each of these applications is incorporated herein by reference in its entirety.This application is directed to synthetic processes for making beta 3 agonists of Formula (I) and Formula (II) and their intermediate compounds.Beta Adrenergic receptors (βAR) are present in detrusor smooth muscle of various species, including human, rat, guinea pig, rabbit, ferret, dog, cat, pig and non-human primate. However, pharmacological studies indicate there are marked species differences in the receptor subtypes mediating relaxation of the isolated detrusor; β1AR predominate in cats and guinea pig, β2AR predominate in rabbit, and β3AR contribute or predominate in dog, rat, ferret, pig, cynomolgus and human detrusor. Expression of βAR subtypes in the human and rat detrusor has been examined by a variety of techniques, and ...

POWER SEMICONDUCTOR DEVICES

A power semiconductor device includes a diode part disposed in a first region of a substrate, a junction field effect transistor (JFET) part disposed in a second region adjacent to the first region of the substrate, an anode terminal disposed on the first region of the substrate, and a cathode terminal disposed on the second region of the substrate. The diode part includes a p-type body region disposed inside the substrate and electrically connected with the anode terminal, an n-type well disposed on one side of the p-type body region and having a first impurity concentration, and a first n-type semiconductor region disposed below the p-type body region and having a second impurity concentration which is lower than the first impurity concentration. 1. A power semiconductor device , comprising:a diode part disposed in a first region of a substrate;a junction field effect transistor (JFET) part disposed in a second region adjacent to the first region of the substrate;an anode terminal disposed on the first region of the substrate; anda cathode terminal disposed on the second region of the substrate, a p-type body region disposed inside the substrate and electrically connected with the anode terminal,', 'an n-type well disposed on one side of the p-type body region, and having a first impurity concentration, and', 'a first n-type semiconductor region disposed below the p-type body region and having a second impurity concentration lower than the first impurity concentration., 'the diode part including2. The power semiconductor device of claim 1 , wherein a bottom of the p-type body region is positioned at a higher level than a bottom of the n-type well.3. The power semiconductor device of claim 1 , wherein an upper portion of a sidewall of the n-type well surrounds the p-type body region claim 1 , and a lower portion of the sidewall of the n-type well surrounds the first n-type semiconductor region.4. The power semiconductor device of claim 1 , further comprising a ...

PROCESS FOR MAKING BETA 3 AGONISTS AND INTERMEDIATES

The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency. 2. The process of claim 1 , wherein the catalyst in step (a) is selected from the group consisting of Pd claim 1 , Raney Ni claim 1 , Pt claim 1 , PdCl claim 1 , and Pd(OH); and reduction reaction is carried out in the presence of hydrogen gas.3. The process of claim 1 , wherein the acid in step (b) is selected from the group consisting of HCl claim 1 , HBr claim 1 , TFA claim 1 , MeSOH claim 1 , TfOH claim 1 , HSO claim 1 , para-toluenesulfonic acid claim 1 , and RSOH wherein R is alkyl claim 1 , aryl or substituted aryl.4. The process of claim 1 , wherein the reduction of step (c) is carried out in the presence of HMDS and the catalyst used is selected from the group consisting of Pt on alumina claim 1 , Pd on alumina claim 1 , Pd/C claim 1 , Pd(OH)—C claim 1 , Raney Ni claim 1 , Rh/C claim 1 , Rh/Al claim 1 , Pt/C claim 1 , Ru/C and PtO.6. The process of claim 5 , wherein the compound I-7 is in a solution claim 5 , and the solution containing compound I-7 is added to a solution containing compound A-4.8. The process of claim 7 , wherein:{'sub': 2', '2, 'the solvent is selected from the group consisting of THF, MTBE, CHCl, MeCN, toluene and a mixture comprising two of the foregoing solvents;'}{'sub': '2', 'the oxidizing agent is selected from the group consisting of NaOCl, NaClO, hydrogen peroxide, pyridine sulfur trioxide, PCC, and DCC; and'}the catalyst is TEMPO or a TEMPO analogue. This application is directed to synthetic processes for making beta 3 agonists of Formula (I) and Formula (II) and their intermediate compounds.Beta Adrenergic receptors (βAR) are present in detrusor smooth muscle of various species, including human, rat, guinea pig, rabbit, ferret, dog, cat, pig and non-human ...

METHOD, SYSTEM AND APPARATUS FOR CREATING VIRTUAL MACHINE

Embodiments of the present invention provide a method, a system, and an apparatus for creating a virtual machine. The method includes: receiving a virtual machine creation request to create a plurality of virtual machines; dividing the plurality of virtual machines into a plurality of virtual machine groups; determining a home physical rack for each virtual machine group, where one virtual machine group corresponds to one home physical rack; and creating each virtual machine group on the home physical rack of each virtual machine group. Because each virtual machine group is created on a home physical rack to which each virtual machine group belongs, each virtual machine group is equivalent to one physical rack. 1. A method for creating a virtual machine , comprising:receiving a virtual machine creation request, wherein the virtual machine creation request is used to create a plurality of virtual machines;determining a plurality of virtual machine groups, wherein different virtual machine groups of the plurality of virtual machine groups comprise different virtual machines of the plurality of virtual machines, wherein virtual machine rack attribute of the virtual machine group denotes that one virtual machine group corresponds to one physical rack;allocating one physical rack to each of the plurality of virtual machine groups; andcreating the plurality of virtual machine groups on the allocated physical racks respectively.2. The method according to claim 1 , wherein the allocating step comprises:allocating different physical racks to different virtual machine groups.3. The method according to claim 1 , wherein the creating step comprises:creating different virtual machines of each of the plurality of virtual machine groups on different physical machines of the allocated physical rack.4. An apparatus claim 1 , comprising:a memory for storing instructions; anda processor, configured to execute the computer-executable instruction, so that the apparatus is configured to: ...

High-formability and super-strength hot galvanizing steel plate and manufacturing method thereof

A high-formability, super-high-strength, hot-dip galvanized steel plate, the chemical composition of which comprises, based on weight percentage, C: 0.15-0.25 wt %, Si: 1.00-2.00 wt %, Mn: 1.50-3.00 wt %, P≦0.015 wt %, S≦0.012 wt %, Al: 0.03-0.06 wt %, N≦0.008 wt %, and the balance of iron and unavoidable impurities. The room temperature structure of the steel plate comprises 10-30% ferrite, 60-80% martensite and 5-15% residual austenite. The steel plate has a yield strength of 600-900 MPa, a tensile strength of 980-1200 MPa, and an elongation of 15-22%. Through an appropriate composition design, a super-high-strength, cold rolled, hot-dip galvanized steel plate is manufactured by continuous annealing, wherein no expensive alloy elements are added; instead, remarkable increase of strength along with good plasticity can be realized just by appropriate augment of Si, Mn contents in combination with suitable processes of annealing and furnace atmosphere control. In addition, the steel plate possesses good galvanization quality that meets the requirement of a super-high-strength, cold rolled, hot-dip galvanized steel plate for automobiles.

PROCESS FOR MAKING CGRP RECEPTOR ANTAGONISTS

The disclosure encompasses a novel process for making piperidinone carboxamide indane and azainane derivatives, having less steps and improved yields as compared to previous synthetic methods for making these compounds, which are CGRP receptor antagonists, useful for the treatment of migraine. Conditions for an amide bond formation between an acid and amine include for example reacting the compounds of Formulae B (after salt break) and C with an amide coupling reagent and optionally an additive and an acid and/or a base in a non-reactive solvent. 2. The process according to where the compound of Formula B is coupled with a compound of Formula C after salt break by reacting the reagents with an amide coupling reagent in a non-reactive solvent to yield a compound of Formula I.3. The process according to wherein the amide coupling reagent is selected from the group consisting of EDC claim 2 , HATU claim 2 , T3P® and CDI claim 2 , and the non-reactive solvent is an organic/aqueous mixture selected from the group consisting of DCM/water claim 2 , iPAC/water claim 2 , acetonitrile/water claim 2 , acetone/water claim 2 , iPA/water and THF/water.4. The process according to further comprising an amide coupling reagent additive selected from the group consisting of HOBT and HOPO.5. The process according to wherein a salt of a compound of Formula C is coupled to the compound of Formula B.6. The process according to wherein the arylaldehyde derivative is selected from 2-hydroxybenzaldehyde claim 1 , 2-hydroxy-5-nitrobenzaldehyde and 2-hydroxy-3 claim 1 ,5-dichlorobenzaldehyde.8. The process according to wherein the electrophilic alkylating agent is R—OS(O)CFor R—OS(O)F claim 7 , or R—OS(O)R claim 7 , wherein Ris a polyfluorinated one to six membered carbon chain.9. The process according to wherein: Z is t-butyl-O—C(O)— claim 8 , deprotection is effected by reacting the compound of Formula D with a second acid claim 8 , the base is a lithium base claim 8 , the additive is an ...

CHIP PACKAGING METHOD AND CHIP PACKAGE UNIT

The present invention provides a chip packaging method, which includes: providing a base material, which includes plural finger contacts; disposing plural chips on the base material by flip chip mounting technology, and disposing plural vertical heat conducting elements surrounding each of the chips to connect the finger contacts on the base material; providing a packaging material to encapsulate the base material, the chips, and the vertical heat conducting elements; adhering a metal film on the packaging material via an adhesive layer, to form a package structure; and cutting the package structure into plural chip package units, wherein each of the chip package units includes one of the chips, a portion of the base material, a portion of the metal film, and a portion of the vertical heat conducting elements surrounding the chip. 1. A chip packaging method , including:providing a base material, which includes a plurality of finger contacts;disposing a plurality of chip units on the base material and disposing a plurality of vertical heat conduction elements on the base material to surround each of the chip units, the chip units being mounted on the base material by flip chip mounting technology, and the vertical heat conduction elements are respectively disposed on and in contact with the corresponding finger contacts;providing a package material, to encapsulate the base material, the chip units and the vertical heat conduction elements;adhering a metal film on the packaging material via an adhesive layer, to form a package structure; andcutting the package structure into a plurality of chip package units, wherein each of the chip package units includes one of the chips, a portion of the base material, a portion of the metal film, and a portion of vertical heat conducting elements surrounding the chip.2. The chip packaging method according to claim 1 , wherein the base material includes a lead frame or a printed circuit board.3. The chip packaging method according ...

Chip packaging method and chip package unit

A chip packaging method includes: providing a wafer, on which multiple bumps are formed; cutting the wafer into multiple chip units, wherein multiple vertical heat conduction elements are formed on the wafer or the chip units; disposing the chip units on a base material; and providing a package material to encapsulate lateral sides and a bottom surface of each of the chip units, to form a chip package unit, wherein the bottom surface of the chip unit faces the base material; wherein, in the chip package unit, the bumps on the chip units abut against the base material, and wherein the vertical heat conduction elements directly connect to the base material, or the base material includes multiple through-holes and the vertical heat conduction elements pass through the multiple through-holes in the base material.

PROCESS FOR THE PREPARATION OF CHIRAL TERT-BUTYL 4-((1R,2S,5R)-6-(BENZYLOXY)-7-OXO-1,6-DIAZABICYCLO[3.2.1]OCTANE-2-CARBOXAMIDO)PIPERIDINE-1-CARBOXYLATE DERIVATIVES AND (2S,5R)-7-OXO-N-PIPERIDIN-4-YL-6-(SULFOXY)-1,6-DIAZABICYCLO[3.2.1]OCTANE-2-CARBOXAMIDE

A process for the preparation of N-protected 6-(piperidin-4-ylcarbamoyl)piperidin-3-yl sulfonates of Formula (III): which comprises contacting a lactone of Formula (II): with an azacycloalkylamine of formula (II-Am): followed by contact with a sulfonyl halide of formula (II-Su): R—SOW (II-Su) in the presence of tertiary amine base, wherein Pand Pare amine protective groups; k, p and q are 0, 1, or 2, and W, R, R, R, R, R, R, R, and Rare defined herein. Additional embodiments add a series of process steps leading to the synthesis of 7-oxo-1,6-diazabicyclo[3.2.1]octanes suitable for use as β-lactamase inhibitors. 20. The process according to claim 19 , wherein the acid is trimethylsilyl iodide (TMSI).21. The process according to claim 20 , wherein the TMSI is in the presence of N claim 20 , O-Bis(trimethylsilyl)acetamide (BSA) or N claim 20 ,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA).22. The process of claim 19 , wherein Compound 8 is directly crystallized as a monohydrate from the reaction mixture. The invention is related to the preparation of N-protected 6-(piperidin-4-ylcarbamoyl)piperidin-3-yl sulfonates. These sulfonates are suitable for use as intermediates that lead via a series of additional process steps to the synthesis of 7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamides and esters. The invention is also related to a final process step for the preparation of, the beta lactamase inhibitor, (2S,5R)-7-oxo-N-piperidin-4-yl-6-(sulfoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide.Certain 7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamides are inhibitors of β-lactamase and, when used in conjunction with β-lactam antibiotics, can be effective for the treatment of bacterial infections. See, for example, International Patent Application Publication No. WO2009/091856 which discloses 7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamides and their synthesis from a ketosulfoxonium ylide intermediate containing an amide side chain, where the ylide intermediate is ...

Cube cabinet

This disclosure relates to a cube rotating cabinet, which comprises: a base, the storage boxes, a rotating mechanism and a hinge. Each storage box is a six-sided cube, one side of which is open. The base of the structure does not move nor rotate. The first side of the base is in contact with the ground, and the second side is in contact with different layers of storage boxes; each layer has four storage boxes, and the opening side of two of the boxes are the same in each layer and are in the opposite direction of the other two. The opening direction between the boxes of the adjacent layers is 90 degrees apart; each layer there is a hinge connection between two adjacent boxes; a rotating mechanism is arranged between the boxes of the adjacent ones, so that the box rotates with the rotating mechanism as a rotating shaft, and the maximum rotation can be to a 180 degrees maximum; surface of the base which is in contact with the storage boxes is provided with four rotating mechanisms, so that the first layer of the box in contact with the surface of the base rotates with the rotating mechanism as a rotating shaft; each layer of the moving device drives the rotation of the box of the next layer and when the upper and lower two boxes are opened or closed, the rotation direction of adjacent layers is opposite.

Process for Making CGRP Receptor Antagonists

The invention encompasses a novel process for making piperidinone carboxamide indane and azainane derivatives, which are CGRP receptor antagonists useful for the treatment of migraine. 111-. (canceled)12. Crystalline (S)—N-((3S ,5S ,6R)-6-methyl-2-oxo-1-(2 ,2 ,2-trifluoroethyl)-5-(2 ,3 ,6-trifluorophenyl)piperidin-3-yl)-2′-oxo-1′ ,2′ ,5 ,7-tetrahydrospiro[cyclopenta[b]pyridine-6 ,3′-pyrrolo[2 ,3-b]pyridine]-3-carboxamide monohydrate.13. Crystalline (S)—N-((3S claim 12 ,5S claim 12 ,6R)-6-methyl-2-oxo-1-(2 claim 12 ,2 claim 12 ,2-trifluoroethyl)-5-(2 claim 12 ,3 claim 12 ,6-trifluorophenyl)piperidin-3-yl)-2′-oxo-1′ claim 12 ,2′ claim 12 ,5 claim 12 ,7-tetrahydrospiro[cyclopenta[b]pyridine-6 claim 12 ,3′-pyrrolo[2 claim 12 ,3-b]pyridine]-3-carboxamide monohydrate according to having a DSC extrapolated onset melting temperature of about 144° C. and a DSC peak melting temperature of about 175° C.14. Crystalline (S)—N-((3S claim 12 ,5S claim 12 ,6R)-6-methyl-2-oxo-1-(2 claim 12 ,2 claim 12 ,2-trifluoroethyl)-5-(2 claim 12 ,3 claim 12 ,6-trifluorophenyl)piperidin-3-yl)-2′-oxo-1′ claim 12 ,2′ claim 12 ,5 claim 12 ,7-tetrahydrospiro[cyclopenta[b]pyridine-6 claim 12 ,3′-pyrrolo[2 claim 12 ,3-b]pyridine]-3-carboxamide monohydrate according to having d-spacings determined by x-ray powder diffraction claim 12 , Cu K alpha claim 12 , of about 12.7 claim 12 , 8.9 claim 12 , 8.1 claim 12 , 7.4 claim 12 , 6.4 claim 12 , 5.2 claim 12 , 4.9 claim 12 , 4.8 and 4.0 angstroms.15. Crystalline (S)—N-((3S claim 12 ,5S claim 12 ,6R)-6-methyl-2-oxo-1-(2 claim 12 ,2 claim 12 ,2-trifluoroethyl)-5-(2 claim 12 ,3 claim 12 ,5-trifluorophenyl)piperidin-3-yl)-2′-oxo-1′ claim 12 ,2′ claim 12 ,5 claim 12 ,7-tetrahydrospiro[cyclopenta[b]pyridine-6 claim 12 ,3′-pyrrolo[2 claim 12 ,3-b]pyridine]-3-carboxamide. The official copy of the Sequence Listing is submitted concurrently with the specification as an ASCII formatted text file via EFS-Web, with a file name of “23236USPSP-SEQLIST-09MAY2012”, a ...

INTERMEDIATES FOR PREPARING CGRP RECEPTOR ANTAGONISTS

The invention encompasses a novel process for making piperidinone carboxamide indane and azainane derivatives, which are CGRP receptor antagonists useful for the treatment of migraine. 116-. (canceled) The official copy of the Sequence Listing is submitted concurrently with the specification as an ASCII formatted text file via EFS-Web, with a file name of “23236USPSP-SEQLIST-9 May 2012”, a creation date of May 9, 2012, and a size of 4,509 bytes. The Sequence Listing filed via EFS-Web is part of the Specification and is incorporated in its entirety by reference herein.This invention relates to a process for making piperidinone carboxamide indane and azainane derivatives, which are CGRP receptor antagonists useful for the treatment of migraine. This class of compounds is described in U.S. patent application Ser. Nos. 13/293,166 filed Nov. 10, 2011, 13/293,177 filed Nov. 10, 2011 and 13/293,186 filed Nov. 10, 2011, and PCT International Application Nos. PCT/US11/60081 filed Nov. 10, 2011 and PCT/US11/60083 filed Nov. 10, 2011.CGRP (Calcitonin Gene-Related Peptide) is a naturally occurring 37-amino acid peptide that is generated by tissue-specific alternate processing of calcitonin messenger RNA and is widely distributed in the central and peripheral nervous system. CGRP is localized predominantly in sensory afferent and central neurons and mediates several biological actions, including vasodilation. CGRP is expressed in alpha- and beta-forms that vary by one and three amino acids in the rat and human, respectively. CGRP-alpha and CGRP-beta display similar biological properties. When released from the cell, CGRP initiates its biological responses by binding to specific cell surface receptors that are predominantly coupled to the activation of adenylyl cyclase. CGRP receptors have been identified and pharmacologically evaluated in several tissues and cells, including those of brain, cardiovascular, endothelial, and smooth muscle origin.Based on pharmacological properties ...

METHOD, APPARATUS, AND ARTIFICIAL INTELLIGENCE EDITOR FOR IMPLEMENTING ARTIFICIAL INTELLIGENCE BEHAVIOR

Methods, apparatus and artificial intelligence (AI) editors for implementing an AI behavior are provided herein. In an exemplary method, an AI behavior configuration file can be obtained. The AI behavior configuration file can be configured using at least one preset component, and the AI behavior configuration file matches logic of a preset AI behavior. It can be tested whether a result of running the AI behavior configuration file reaches a preset effect. When the result of running the AI behavior configuration file reaches the preset effect, the preset AI behavior can be implemented according to the AI behavior configuration file. 1. A method for implementing an artificial intelligence (AI) behavior , comprising:obtaining an AI behavior configuration file, wherein the AI behavior configuration file is configured using at least one preset component and the AI behavior configuration file matches logic of a preset AI behavior;testing whether a result of running the AI behavior configuration file reaches a preset effect; andwhen the result of running the AI behavior configuration file reaches the preset effect, implementing the preset AI behavior according to the AI behavior configuration file.2. The method according to claim 1 , wherein before obtaining the AI behavior configuration file claim 1 , the method further comprises:encapsulating code for implementing specific functions into components for implementing the specific functions;storing, in node configuration, each component of the components for implementing the specific functions and one or more of a type, a function, detailed information, an initialization parameter, and mounting topology, of the each component; and 'calling the at least one preset component from the node configuration to configure the AI behavior configuration file.', 'wherein the obtaining of the AI behavior configuration file comprises3. The method according to claim 2 , wherein the obtaining of the AI behavior configuration file ...

Method, apparatus, and artificial intelligence server for determining artificial intelligence behavior

According to methods, apparatus and AI servers for determining an AI behavior, a protocol-requesting command sent by an application logic server can be received. The protocol-requesting command can contain an application identifier, a notification message, and current environment data. From a plurality of preset AI systems, an AI system corresponding to the application identifier can be found. The AI system can be formed by a preset plurality of components that include one or more classifying components. From the AI system, a classifying component corresponding to the notification message can be found. The classifying component can be mounted with at least one behavior component. From the classifying component corresponding to the notification message, a behavior component matching the current environment data can be obtained. An AI behavior can be determined based on the obtained behavior component matching the current environment data.

PROCESS FOR MAKING BETA 3 AGONISTS AND INTERMEDIATES

The present invention is directed to a process for preparing a compound of formula I-11 through multiple-step reactions. 2. The process of claim 1 , wherein in step (c):{'sub': 2', '2, 'the solvent is selected from the group consisting of THF, MTBE, CHCl, MeCN, toluene and a mixture comprising two of the foregoing solvents;'}{'sub': '2', 'the oxidizing agent is selected from the group consisting of NaOCl, NaClO, hydrogen peroxide, pyridine sulfur trioxide, PCC, and DCC; and'}the catalyst is TEMPO or a TEMPO analogue.3. The process of claim 1 , wherein the reaction between I-7 and A-4 in step (d) is carried out at a temperature of about 20 to 40° C. and in the presence of a solvent selected from the group consisting of THF claim 1 , MTBE claim 1 , CHCl claim 1 , MeCN claim 1 , toluene and a mixture comprising two of the foregoing solvents.4. The process of claim 1 , wherein the catalyst used in step (e) is selected from the group consisting of Pd claim 1 , Raney Ni claim 1 , Pt claim 1 , PdCl claim 1 , and Pd(OH); and the reduction is carried out in the presence of hydrogen gas5. The process of claim 1 , wherein the acid in step (f) is selected from the group consisting of HCl claim 1 , HBr claim 1 , TFA claim 1 , MeSOH claim 1 , TfOH claim 1 , HSO claim 1 , para-toluenesulfonic acid claim 1 , and RSOH wherein R is alkyl claim 1 , aryl or substituted aryl.6. The process of claim 1 , wherein the reduction of step (g) is carried out in the presence of HMDS and the catalyst used is selected from the group consisting of Pt on alumina claim 1 , Pd on alumina claim 1 , Pd/C claim 1 , Pd(OH)—C claim 1 , Raney Ni claim 1 , Rh/C claim 1 , Rh/Al claim 1 , Pt/C claim 1 , Ru/C and PtO.8. The process of claim 7 , wherein the KRED enzyme is selected from the group consisting of a polypeptide of SEQ ID NO. 1 and a polypeptide of SEQ ID NO. 2.9. The process of claim 8 , further comprising a cofactor recycling system selected from the group consisting of a polypeptide of SEQ ID NO. 3 ...

METHODS AND INTERMEDIATES FOR PREPARING MACROLACTAMS

The present invention includes compounds useful as intermediates in the preparation of macrolactams, methods for preparing the intermediates, and methods for preparing macrolactams. One use of the methods and intermediates described herein is in the production of macrolactam compounds able to inhibit HCV NS3 protease activity. HCV NS3 inhibitory compounds have therapeutic and research applica 11. The method of claim 10 , wherein the reaction uses tri tert-butylphosphine tetra fluoroborate salt in a solvent claim 10 , and Compound 8 is provided as either a dibenzylamine salt or a t-butylamine salt. The present invention relates to process and intermediates that can be used for preparing macrolactams. One use of the methods and intermediates described herein is the production of macrolactam compounds able to inhibit HCV NS3 protease activity. HCV NS3 inhibitory compounds have therapeutic and research applications.Hepatitis C virus (HCV) infection is a major health problem. HCV infection leads to chronic liver disease, such as cirrhosis and hepatocellular carcinoma, in a substantial number of infected individuals.Several virally-encoded enzymes are putative targets for therapeutic intervention, including a metalloprotease (NS2-3), a serine protease (NS3), a helicase (NS3), and an RNA-dependent RNA polymerase (NS5B). The NS3 protease is located in the N-terminal domain of the NS3 protein. NS4A provides a cofactor for NS3 activity.Potential treatments for HCV infection are discussed in different references including Balsano, 8(4):307-318, 2008, Rönn et al., 8:533-562, 2008, Sheldon et al., 16(8):1171-1181, 2007, and De Francesco et al., 58:1-16, 2003.Examples of publications describing macrolactam compounds able to inhibit HCV protease activity include: Harper et al., WO2010011566; Liverton et al., WO2009134624; McCauley et al., WO2009108507; Liverton et al., WO2009010804; Liverton et al., WO2008057209; Liverton et al., WO2008051477; Liverton et al., WO2008051514; ...

TWO-DIMENSIONAL (2D) BISMUTH NANOCOMPOSITE, AND PREPARATION METHOD AND USE THEREOF

The disclosure relates to a two-dimensional (2D) bismuth nanocomposite, and a preparation method and use thereof, and belongs to the field of nanobiotechnology. The 2D bismuth nanocomposite of the disclosure is an ultra-thin bismuth nanosheet that is loaded with platinum nanoparticles and modified with indocyanine green (ICG) and surface targeting polypeptide Ang-2. The 2D bismuth nanocomposite Bi@Pt/ICG-Ang2 of the disclosure can not only realize the targeted photothermal and photodynamic combination therapy for tumors, but also realize the dual-mode imaging combining CT and fluorescence imaging. 1. A two-dimensional (2D) bismuth nanocomposite , the 2D bismuth nanocomposite comprising:an ultra-thin bismuth nanosheet that is loaded with platinum nanoparticles and modified with indocyanine green (ICG) and surface targeting polypeptide Ang-2, wherein the ultra-thin bismuth nanosheet has a thickness of 1 nm to 5 nm.2. The 2D bismuth nanocomposite according to claim 1 , wherein claim 1 , the ultra-thin bismuth nanosheet has an irregular shape claim 1 , and a length of 10 nm to 300 nm.3. A method for preparing the 2D bismuth nanocomposite according to claim 1 , the method comprising the following steps:1) mixing a bismuth powder with an exfoliation solvent, and then grinding a resulting mixture to obtain a bismuth particle solution;2) subjecting the bismuth particle solution obtained in step 1) to probe ultrasonic exfoliation in an ice bath and then to a first centrifugation, and collecting a resulting supernatant to obtain an ultra-thin bismuth nanosheet solution; subjecting the ultra-thin bismuth nanosheet solution to a second centrifugation, and collecting a resulting precipitate to obtain a bismuth nanosheet; adding water to the bismuth nanosheet to obtain a bismuth nanosheet solution; and subjecting the bismuth nanosheet solution to lyophilization to obtain a bismuth nanosheet powder;3) placing the bismuth nanosheet powder obtained in step 2) in an atomic deposition ...

Process for Making Beta 3 Agonists and Intermediates

The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency. 2. The process of claim 1 , wherein the catalyst in step (a) is selected from the group consisting of Pd claim 1 , Raney Ni claim 1 , Pt claim 1 , PdCl claim 1 , and Pd(OH); and reduction reaction is carried out in the presence of hydrogen gas.3. The process of claim 1 , wherein the acid in step (b) is selected from the group consisting of HCl claim 1 , HBr claim 1 , TFA claim 1 , MeSOH claim 1 , TfOH claim 1 , HSO claim 1 , para-toluenesulfonic acid claim 1 , and RSOH wherein R is alkyl claim 1 , aryl or substituted aryl.4. The process of claim 1 , wherein the reduction of step (c) is carried out in the presence of HMDS and the catalyst used is selected from the group consisting of Pt on alumina claim 1 , Pd on alumina claim 1 , Pd/C claim 1 , Pd(OH)—C claim 1 , Raney Ni claim 1 , Rh/C claim 1 , Rh/Al claim 1 , Pt/C claim 1 , Ru/C and PtO.6. The process of claim 5 , wherein the compound I-7 is in a solution claim 5 , and the solution containing compound I-7 is added to a solution containing compound A-4.8. The process of claim 7 , wherein:{'sub': 2', '2, 'the solvent is selected from the group consisting of THF, MTBE, CHCl, MeCN, toluene and a mixture comprising two of the foregoing solvents;'}{'sub': '2', 'the oxidizing agent is selected from the group consisting of NaOCl, NaClO, hydrogen peroxide, pyridine sulfur trioxide, PCC, and DCC; and'}the catalyst is TEMPO or a TEMPO analogue.15. A process according to claim 11 , wherein said acid is HCl. This application is directed to synthetic processes for making beta 3 agonists of Formula (I) and Formula (II) and their intermediate compounds.Beta Adrenergic receptors (βAR) are present in detrusor smooth muscle of various species, including human, ...

Sol-Gel Route for Nano Sized LiFePO4/C for High Performance Lithium Ion Batteries

This invention relates to a novel a sol-gel method of synthesizing uniformly carbon-coated LiFeP0(LiFeP0/AS). The method including the steps of: mixing a lithium source a phosphoric source and a carbon source with a solution containing Fe ions to form a gel; and calcining the gel to provide uniformly carbon-coated LiFeP0(LiFePO/AS). According to the invention, the phosphoric source is a phosphonic acid. 1. A method of synthesizing uniformly carbon-coated LiFePOincluding the steps of:mixing a lithium source, a phosphoric source and a carbon source with a solution containing Fe ions, wherein the molar ratio of P:Fe:Li is 2.0-5.0:0.4-2.0:1, adding water to form a sol and milling the sol following evaporation of water to form a gel; and{'sub': 4', '4, 'calcining the gel to provide uniformly carbon-coated LiFePO(LiFePO/AS);'}wherein the phosphoric source is a phosphonic acid, and the Fe ions are from a ferric source.2. The method claimed in claim 1 , wherein the phosphoric source and the carbon source is the same source.3. The method claimed in claim 2 , wherein the phosphoric source is an organophosphonic acid.4. The method claimed in claim 3 , wherein the organophosphonic acid is amino tris (methylene phosphonic acid) or diethylene triamine penta (methylene phosphonic acid).5. The method claimed in claim 1 , wherein the lithium source is selected from lithium carbonate claim 1 , lithium nitrate claim 1 , lithium acetate claim 1 , lithium hydroxide and/or lithium oxalate.6. The method claimed in claim 1 , wherein the ferric source is ferric nitrate.7. (canceled)8. (canceled)9. (canceled)10. (canceled)11. (canceled)12. (canceled)13. The method claimed in claim 1 , wherein the gel is dried claim 1 , subjected to a pre-calcination step claim 1 , and then calcined.14. The method claimed in claim 13 , wherein the pre-calcination step is at 100°-500° C. for 1-6 hours claim 13 , with heating ramping rate of 1-10° C./min.15. The method claimed in claim 13 , wherein the ...

Process for Making Beta 3 Agonists and Intermediates

The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency. 114.-. (canceled)17. The method of claim 16 , further comprising adjusting the pH to from 6.5 to 7.0.18. The method of claim 16 , wherein the molar ratio of the compound of formula A-4 to the compound of formula I-7 is from about 1:1 to about 1.2:1.19. The method of claim 16 , further comprising dissolving the compound of formula A-4 in a solvent to form a solution prior to the addition of the compound of formula I-7.20. The method of claim 19 , wherein the solvent is selected from THF claim 19 , MTBE claim 19 , CHCl claim 19 , MeCN claim 19 , toluene claim 19 , and a mixture thereof.21. The method of claim 19 , further comprising adding a base to the solution prior to the addition of the compound of formula I-7.22. The method of claim 21 , wherein the base is a tertiary amine.23. The method of claim 22 , wherein the base is N claim 22 ,N-diisopropylethylamine.24. The method of claim 21 , further comprising adding a salt to the solution prior to the addition of the compound of formula I-7.25. The method of claim 24 , wherein the salt is a lithium halide.26. The method of claim 25 , wherein the salt is selected from lithium chloride and lithium bromide.27. The method of claim 16 , which is conducted at a temperature of from about 25° C. to about 40° C. This is a continuation application of U.S. application Ser. No. 16/590,180, filed on Oct. 1, 2019, which is a continuation of U.S. application Ser. No. 16/133,320, filed on Sep. 17, 2018, which is a continuation of U.S. application Ser. No. 15/808,740, filed on Nov. 9, 2017, which is a divisional application of U.S. application Ser. No. 15/057,427, filed on Mar. 1, 2016, which is a continuation application of U.S. application Ser. No. 14/354,158, ...

COLD-ROLLED HIGH-STRENGTH STEEL PLATE HAVING EXCELLENT PHOSPHATING PERFORMANCE AND FORMABILITY AND MANUFACTURING METHOD THEREFOR

A cold-rolled high-strength steel plate having excellent phosphating performance and formability and a manufacturing method therefor. The chemical composition of the steel plate is, in percentage by weight, C 0.01-0.20%, Si 1.50-2.50%, Mn 1.50-2.50%, P≤0.02%, S≤0.02%, Al 0.03-0.06%, N≤0.01%, the remainder being Fe and impurities. The surface layer of the steel plate has an inner oxide layer with a thickness of 1-5 μm, and there is no enrichment of Si and Mn on the surface of the steel plate. The steel plate has good phosphating performance and formability, with a tensile strength of ≥980 MPa and an elongation of ≥20%. The structure at the room temperature contains retained austenite, ferrite, and martensite and/or bainite. In the method, the dew point of atmosphere in a heating zone and a soaking zone is controlled during continuous annealing, to inhibit the enrichment of elements such as Si and Mn on the surface of the steel plate, and transition external oxidation to internal oxidation, so that the steel plate has good phosphating performance. 1. A cold-rolled high-strength steel plate having excellent phosphatability and formability , comprising chemical elements in percentage by mass of: C 0.10 to 0.20% , Si 1.50 to 2.50% , Mn 1.50 to 2.50% , P≤0.02% , S≤0.02% , Al 0.03 to 0.06% , N≤0.01% , and a balance of Fe and unavoidable impurity elements , wherein a surface layer of the cold-rolled high-strength steel plate comprises an inner oxide layer having a thickness of 1 to 5 μm; the inner oxide layer comprises iron as a matrix; the matrix comprises oxide particles which are at least one of Si oxides , composite oxides of Si and Mn; and no Si or Mn element is enriched in the surface of the steel plate; [{'br': None, 'i': A=', '×d, 'sup': '1/2', '0.115×(0.94×[Si]+0.68×[Mn])'}, {'br': None, 'i': B=', '×d, 'sup': '1/2', '1.382×(0.94×[Si]+0.68×[Mn])'}, {'br': None, 'A≤λ≤B'}], 'wherein the oxide particles have an average diameter of 50 to 200 nm and an average spacing λ ...

COLD-ROLLED HIGH-STRENGTH STEEL PLATE HAVING EXCELLENT PHOSPHATING PERFORMANCE AND FORMABILITY AND MANUFACTURING METHOD THEREFOR

A cold-rolled steel plate () and a manufacturing method therefor. The chemical composition of the steel plate () in percentage by weight is: C 0.15-0.25%, Si 1.50-2.50%, Mn 2.00-3.00%, P≤0.02%, S≤0.01%, Al 0.03-0.06%, N≤0.01%, with the balance being Fe and impurities. The surface layer has an inner oxide layer () with a thickness of 1-5 μm, and there is no enrichment of Si or Mn on the surface. The steel plate () has good phosphating performance and formability, with a tensile strength of ≥1180 MPa and an elongation of ≥14%, and has a complex-phase structure of ferrite, martensite, and retained austenite, the content of the retained austenite being not lower than 5%. A dew point is at −25° C. to 10° C. in continuous annealing, such that external oxidation transitions to internal oxidation. 1. A cold-rolled high-strength steel plate having excellent phosphatability and formability , comprising chemical elements in percentage by mass of: C 0.15 to 0.25% , Si 1.50 to 2.50% , Mn 2.00 to 3.00% , P≤0.02% , S≤0.01% , Al 0.03 to 0.06% , N≤0.01% , and a balance of Fe and unavoidable impurity elements , wherein a surface layer of the steel plate comprises an inner oxide layer having a thickness of 1 to 5 μm; the inner oxide layer comprises iron as a matrix; the matrix comprises oxide particles which are at least one of oxides of Si , composite oxides of Si and Mn; no Si or Mn element is enriched in the surface; [{'br': None, 'i': A=', '×d, 'sup': '1/2', '0.247×(0.94×[Si]+0.68×[Mn])'}, {'br': None, 'i': B=', '×d, 'sup': '1/2', '1.382×(0.94×[Si]+0.68×[Mn])'}, {'br': None, 'A≤λ≤B'}], 'the oxide particles have an average diameter of 50 to 200 nm and an average spacing X, between the oxide particles satisfying the following relationshipwherein [Si] is the content % of Si in the steel; [Mn] is the content % of Mn in the steel; and d is the diameter of the oxide particles in nm.2. The cold-rolled high-strength steel plate having excellent phosphatability and formability according to ...

Hot dipped high manganese steel and manufacturing method therefor

A hot dipped high manganese steel and a manufacturing method therefor. The high manganese steel comprises a steel base plate and a coating on the surface of the steel base plate. The core of the steel base plate is austenite. The surface layer of the steel base plate is a ferrite fine grain layer. The ferrite fine grain layer comprises an oxide of Al. Furthermore, the steel base plate of the hot dipped high manganese steel comprises, in mass percentages, 10 to 30% of Mn element, 1 to 2% of Al element, and 0.4 to 0.8% of C element. The manufacturing method comprises: 1) manufacturing strip steel; 2) primary annealing and acid washing; 3) secondary annealing and hot dipping.

CONTENT SHARING FOR MOBILE DEVICES

Aspects of the subject matter described herein relate to content sharing for mobile devices. In aspects, images that are created using mobile devices may be automatically uploaded to one or more targets. In addition, images created on the one or more targets may be automatically downloaded to the mobile device based on one or more criteria. A service facilitates transfer of images in both directions and includes a pluggable architecture in which forwarders for new targets may be added. 1. A computer storage medium , the computer storage medium being hardware and storing computer-executable instructions , which when executed perform actions , comprising:receiving an indication of an image that has been created using a mobile device;obtaining configuration data that indicates whether the image is to be included in a stream;creating a package that includes the image and indicates the stream;determining additional fields, if any, to include in the package, the additional fields providing additional information about the image; andtransmitting the package to a service, the service responsible for communicating with a target device to provide the image to the target device, the service transmitting the stream that includes the image and other images.2. The computer storage medium of claim 1 , the actions further comprising:receiving input indicative of user preferences, the input indicating whether images are to be automatically uploaded, the input also indicating one or more destinations external to the mobile device to which the images are to be sent if uploaded;updating the configuration data to reflect the user preferences; andstoring the configuration data on a store of the mobile device.3. The computer storage medium of claim 1 , the action further comprising claim 1 , if the image is to be automatically uploaded to the service claim 1 , refraining from providing a query as to whether to upload the image to a user interface of the mobile device before transmitting ...

METHODS AND INTERMEDIATES FOR PREPARING MACROLACTAMS

The present invention includes compounds useful as intermediates in the preparation of macrolactams, methods for preparing the intermediates, and methods for preparing macrolactams. One use of the methods and intermediates described herein is in the production of macrolactam compounds able to inhibit HCV NS3 protease activity. HCV NS3 inhibitory compounds have therapeutic and research applications. 4. The method of claim 3 , wherein X is Br.6. The method of claim 1 , wherein Ris acetyl.8. The method of claim 1 , wherein Ris selected from the group consisting of C-Calkyl groups.9. The method of claim 2 , wherein Ris tert-butyl.10. The method of claim 1 , wherein LG is Cl.11. The method of claim 1 , wherein claim 1 , in step (1) claim 1 , the chiral alcohol is chlorohydrin.14. The method of claim 1 , wherein step (iii) is conducted in the presence of a promoter.15. The method of claim 14 , wherein the promoter is selected from the group consisting of 2-hydroxypyridine-N-oxide claim 14 , hydroxyl succinimide claim 14 , imidazole and imidazole HCl salt.16. The method of claim 5 , wherein step (iv) comprises forming a salt of the compound claim 5 , wherein the salt is selected from tert-butylamine salt claim 5 , dibenzylamine salt claim 5 , and dicyclohexyl amine salt. The present invention relates to process and intermediates that can be used for preparing macrolactams. One use of the methods and intermediates described herein is the production of macrolactam compounds able to inhibit HCV NS3 protease activity. HCV NS3 inhibitory compounds have therapeutic and research applications.Hepatitis C virus (HCV) infection is a major health problem. HCV infection leads to chronic liver disease, such as cirrhosis and hepatocellular carcinoma, in a substantial number of infected individuals.Several virally-encoded enzymes are putative targets for therapeutic intervention, including a metalloprotease (NS2-3), a serine protease (NS3), a helicase (NS3), and an RNA-dependent RNA ...

Process for Making Nucleoside Phosphoramidate Compounds

The present invention is directed to a process for making Nucleoside Phosphoramidate Compounds of formula (I): which are useful for the treatment and prophylaxis of HCV infection. The present invention is also directed to compounds that are useful as synthetic intermediates for making the compounds of formula (I).

ELECTRONIC DEVICE

The present disclosure relates to a type of electronic device, comprising an internal circuit and a surface structure. The internal circuit comprises a circuit board, a feed portion, and a coupler. The surface structure comprises a rectangular display, a metal casing, an elongated metal plate, a connection element, a resonant element, and a dielectric material. The circuit board is provided with a reference plane and a transceiver installed thereon. The feed portion is electrically connected to the transceiver. The coupler is electrically connected to the feed portion. The rectangular display is located at the top portion of the electronic device. The metal casing is electrically connected to the reference plane of the circuit board, forming an integrated reference ground. The elongated metal plate is located on one side surface of the electronic device and is separated from the edge of the metal casing by a gap. The connection element is located within the gap and connects the elongated metal plate and the metal casing. The resonant element comprises a part of the edge of the elongated metal plate, the connection element, and a part of the edge of the metal casing connected to each other. The resonant element and the coupler are separated. The coupler is capacitively coupled to the resonant element. The dielectric material fills the gap. 1. An electronic device , the electronic device comprising:an internal circuit, wherein the internal circuit comprises:a circuit board, wherein the circuit board is provided with a reference plane and a transceiver installed thereon;a feed portion, wherein the feed portion is electrically connected to the transceiver; anda coupler, wherein the coupler is electrically connected to the feed portion; as well as a surface structure, wherein the surface structure comprises:a rectangular display, wherein the rectangular display is positioned on the top face of the electronic device;a metal casing, wherein the metal casing is electrically ...

PROTECTIVE COATING FOR SUBSTRATE AND PREPARATION METHOD THEREFOR

A wear-resistant super-hydrophobic protective coating for a substrate includes a pretreated surface and a composite coating. The composite coating is formed of a mixture of a ZrOpowder, a PTFE powder and a silicone powder by spraying. A method for preparing the protective coating on a substrate is also provided. 1. A protective coating for a substrate , comprising: a pretreated surface and a composite coating , wherein the composite coating is formed of a mixture of a ZrOpowder , a PTFE powder and a silicone powder by spraying.2. The protective coating of claim 1 , wherein the pretreated surface has a rough structure.3. The protective coating of claim 1 , wherein a weight ratio of the ZrOpowder to the PTFE powder to the silicone powder is 9-11:0.9-1.1:0.45-0.55.4. The protective coating of claim 1 , wherein the ZrOpowder contains 7%-9% by weight of yttrium oxide.5. The protective coating of claim 1 , wherein the ZrOpowder has a particle size of 11-125 μm; the PTFE powder has a particle size of 20-60 μm; and the silicone powder has a particle size of 4.0-4.5 μm.6. The protective coating of claim 2 , wherein the substrate is a metal or a ceramic material.7. The protective coating of claim 1 , wherein the composite coating has a thickness of 10-40 μm.8. A method for preparing the protective coating of claim 1 , comprising:subjecting the substrate to sand blasting to produce the pretreated surface; and{'sub': '2', 'spraying the mixture of the ZrOpowder, the PTFE powder and the silicone powder onto the substrate by air plasma spraying.'}9. The method of claim 8 , further comprising:mixing the mixture for 2-2.5 h in a rolling-type ball mill; drying the mixture at 90-95° C. in a drying oven for 1-1.5 h; cooling the mixture; and spraying the cooled mixture onto a surface of the substrate with a spray gun;wherein a moving speed of the spray gun is 440-460 mm/s.10. The method of claim 8 , wherein parameters for the air plasma spraying are set as follows: current: 530-570 A; ...

COLD-ROLLED HIGH-STRENGTH STEEL HAVING TENSILE STRENGTH OF NOT LESS THAN 1500 MPA AND EXCELLENT FORMABILITY, AND MANUFACTURING METHOD THEREFOR

Provided is a cold-rolled high-strength steel having a tensile strength of not less than 1500 MPa and an excellent formability, the chemical elements thereof having the following mass percent ratios: 0.25%-0.40% of C, 1.50%-2.50% of Si, 2.0%-3.0% of Mn, 0.03%-0.06% of Al, P≤0.02%, S≤0.01%, N≤0.01% and at least one of 0.1%-1.0% of Cr and 0.1%-0.5% of Mo, with the balance being Fe and other unavoidable impurities. The microstructure of the cold-rolled high-strength steel has 5%-20% of residual austenite and 70%-90% of martensite, and the carbon concentration ratio of the residual austenite to the martensite is greater than 3.5 and less than 15. The cold-rolled high-strength steel sheet has a high strength and an excellent formability through a rational ingredient design and microstructure control. 1. A cold-rolled high-strength steel having a tensile strength of 1500 MPa or more and excellent formability , comprising the following chemical elements in mass percentage:C: 0.25˜0.40%, Si: 1.50˜2.50%, Mn: 2.0˜3.0%, Al: 0.03˜0.06%, P≤0.02%, S≤0.01%, N≤0.01%, and at least one of 0.1˜1.0% of Cr and 0.1˜0.5% of Mo, with the balance being Fe and other unavoidable impurities;wherein, the microstructure of the cold-rolled high-strength steel has 5˜20% of residual austenite and 70˜90% of martensite, and a ratio of the carbon concentration of the residual austenite to that of the martensite is more than 3.5 and less than 15.2. The cold-rolled high-strength steel according to claim 1 , wherein claim 1 , the microstructure of the cold-rolled high-strength steel comprises residual austenite claim 1 , martensite claim 1 , and ferrite or bainite.3. The cold-rolled high-strength steel according to claim 1 , wherein claim 1 , mass percentages of the chemical elements satisfy: Mn+Cr+Mo≤3.8%.4. The cold-rolled high-strength steel according to claim 1 , wherein mass percentages of the chemical elements satisfy: C+Si/30+Mn/20+2P+4S≤0.56%.5. The cold-rolled high-strength steel according to ...

SUBSTITUTED PHOSPHORAMIDATE COMPOUNDS AND USES THEREOF

The present invention is directed to Compounds of Formula (I) and salts thereof, wherein R, R, Rand Rare defined above herein. The present invention is also directed to uses of the compounds of Formula (I) to add phosphoramidate groups onto organic alcohols. 2. The compound of claim 1 , wherein Ris —O-(5 or 6-membered monocyclic heteroaryl) or —S—(C-Caryl) claim 1 , wherein said 5 or 6-membered monocyclic heteroaryl group and said C-Caryl group can each be optionally substituted with one or more Rgroups.3. (canceled)4. The compound of any of claim 1 , wherein Ris phenyl claim 1 , which can be optionally substituted with one or more Rgroups.5. The compound of claim 1 , wherein Ris —C-Calkyl and Ris —C-Calkyl.6. (canceled)9. The compound of claim 1 , wherein Ris O-pyridyl or S-phenyl claim 1 , each of which can be optionally substituted with halo.10. The compound of claim 1 , wherein Ris methyl and Ris isopropyl.11. (canceled)14. The method of claim 13 , wherein the base is a compound of formula R—YX.15. The method of claim 14 , wherein Ris C-Calkyl claim 14 , Y is Mg and X is Cl.16. The method of claim 13 , wherein organic solvent A is THF.17. The method of claim 13 , wherein the compound of is a compound of .19. The method of claim 12 , wherein Ris isopropyl and Ris methyl.20. (canceled)22. The method of claim 21 , wherein X is O; B is a pyrimidine base; Ris methyl; Ris selected from F claim 21 , Cl claim 21 , —CN claim 21 , C-Calkynyl claim 21 , —NHand —N; and Ris H or —C(O)CH(CH).23. The method of claim 22 , wherein B is uridine and Ris selected from F claim 22 , Cl claim 22 , C-Calkynyl claim 22 , and —CN.24. The method of claim 23 , wherein Ris —CN and Ris —C(O)CH(CH).25. (canceled)26. (canceled) The present invention is directed to Substituted Phosphoramidate Compounds and to uses of the Substituted Phosphoramidate Compounds to add phosphoramidate groups onto organic alcohols.Hepatitis C virus (HCV) infection is a major health problem that leads to chronic ...

LOW PROFILE DUAL-FREQUENCY ANTENNA DEVICE

A low profile dual-frequency antenna device comprises an insulative carrier having a first surface and a second surface which are opposite and a conductor unit, the conductor unit comprises a first conductor which is provided to the first surface and a second conductor which is provided to the second surface and connected with the first conductor, a first radiation slot as a low frequency slot antenna is formed between the first conductor and the second conductor, the first conductor is formed with a second radiation slot, a third radiation slot which is communicated with the first radiation slot and the second radiation slot, a fourth radiation slot and a fifth radiation slot, and the third radiation slot, the fourth radiation slot and the fifth radiation slot together constitute a high frequency slot antenna, the second radiation slot decides an impedance and a resonance frequency width of each antenna, a first side edge and a second side edge is oppositely positioned at a location where the second radiation slot and the third radiation slot are communicated, the first conductor has a signal feeding-in portion thereon close to the first side edge, the first conductor has a ground portion thereon close to the second side edge. 1. A low profile dual-frequency antenna device , comprising:an insulative carrier having a first surface and a second surface which are opposite; anda conductor unit provided on the insulative carrier and comprising a first conductor and a second conductor, the first conductor being provided to the first surface, the second conductor being provided to the second surface and being connected with the first conductor, a first radiation slot being formed between the first conductor and the second conductor, extending along an edge of the insulative carrier and encircling a periphery of the first conductor; and the first conductor being formed with a second radiation slot, a third radiation slot which is communicated with the first radiation slot ...

WIFI ANTENNA DEVICE

The present disclosure discloses a WIFI antenna device, the WIFI antenna device includes a carrier, a grounding portion, a first radiation portion, a second radiation portion and a third radiation portion which all are provided on the carrier. The first radiation portion, the second radiation portion and the third radiation portion are coupled to the grounding portion. The coupling portion couples an electrical signal to the first radiation portion, the second radiation portion and the third radiation portion. The first radiation portion, the second radiation portion and the third radiation portion convert the electrical signal into the radiation signal. The first radiation portion determines a low frequency resonance point of a radiation signal emitted by the WIFI antenna device. The second radiation portion determines a first high frequency resonance point of the radiation signal. The third radiation portion determines a second high frequency resonance point of the radiation signal. 1. A WIFI antenna device , comprising:a carrier;a grounding portion provided on the carrier;a first radiation portion provided on the carrier and coupled to the grounding portion, the first radiation portion determining a low frequency resonance point of a radiation signal emitted by the WIFI antenna device, the low frequency resonance point defining a bandwidth of 2.4-2.84 GHz;a second radiation portion provided on the carrier and coupled to the grounding portion, the second radiation portion determining a first high frequency resonance point of the radiation signal;a third radiation portion provided on the carrier and coupled to the grounding portion, the third radiation portion determining a second high frequency resonance point of the radiation signal, the first high frequency resonance point and the second high frequency resonance point defining a bandwidth of 4.9-5.85 GHz; anda coupling portion coupling an electrical signal to the first radiation portion, the second radiation ...

ANTENNA DEVICE

An antenna device comprises a carrier, a first radiation portion, a second radiation portion and a coupling portion. The first radiation portion, the second radiation portion and the coupling portion are provided on the carrier. The second radiation portion electrically connects with the first radiation portion. The first radiation portion and the second radiation portion share a shared part, the shared part is directly connected to a reference grounding. The coupling portion capacitively couples an electrical signal to the first radiation portion and the second radiation portion. The first radiation portion and the second radiation portion convert the electrical signal into a radiation signal emitted by the antenna device. 1. An antenna device , comprising:a carrier;a first radiation portion provided on the carrier;a second radiation portion provided on the carrier and electrically connecting with the first radiation portion, the first radiation portion and the second radiation portion sharing a shared part, the shared part being directly connected to a grounding face; anda coupling portion provided on the carrier for capacitively coupling an electrical signal to the first radiation portion and the second radiation portion, the first radiation portion and the second radiation portion converting the electrical signal into a radiation signal emitted by the antenna device.2. The antenna device according to claim 1 , wherein the shared part physically contacts a grounding line claim 1 , the grounding line is electrically connected to the grounding face.3. The antenna device according to claim 1 , wherein the coupling portion is insulated from the first radiation portion and the second radiation portion.4. The antenna device according to claim 1 , wherein the coupling portion is independent of the first radiation portion and the second radiation portion.5. The antenna device according to claim 1 , wherein a length of the coupling portion is less than one fourth of a ...

Process for Making Beta 3 Agonists and Intermediates

The present invention is directed to a process for preparing a compound of formula I-11 through multiple-step reactions:

HIGH-FORMABILITY AND SUPER-STRENGTH COLD-ROLLED STEEL SHEET AND MANUFACTURING METHOD THEREOF

A high-formability and super-strength cold-rolled steel sheet and a manufacturing method thereof. The weight percentage of its components is: C 0.15-0.25%, Si 1.00-2.00%, Mn 1.50-3.00%, P≦0.015%, S≦0.012%, Al 0.03-0.06%, N≦0.008%, and the rest are Fe and inevitable impurities. The manufacturing method comprises the following steps: 1) smelting and casting; 2) heating to 117˜1230° C. and performing thermal insulation; 3) performing hot rolling, the finish rolling temperature being 880+30° C., and coiling at 550˜650° C.; and 4) performing acid washing, cold rolling, and annealing, the cold rolling reduction being 40-60%, annealing at 860-920° C., and performing slow cooling to 690-750° C. with the cooling rate of 3˜10° C./s; performing rapid cooling at 240˜320° C., with the cooling speed ≧50° C./s, then heating to 360˜460° C., and performing thermal insulation for 100˜500 s to cool to the room temperature at last. Finally, a high-formability, low-rebound property and super-strength cold-rolled steel sheet with the yield strength of 600˜900 MPa, the tensile strength of 980˜1150 MPa, the elongation of 17˜25% is obtained. 1. A high-formability and ultra-high-strength steel plate , comprising:a) 0.15-0.25 wt % carbon (C)b) 1.00-2.00 wt % silicon (Si)c) 1.50-3.00 wt % manganese (Mn)d) ≦0.015 wt % phosphorus (P)e) ≦0.012 wt % sulfur (S)f) 0.03-0.06 wt % aluminum (Al)g) ≦0.008 wt % nitrogen (N)h) a balance of iron (Fe) and unavoidable impurities;wherein the steel plate structure at room temperature consists of 10%-30% ferrite, 60-80% martensite, and 5-15% residual austenite;wherein the steel plate exhibits a yield strength of 600-900 MPa, a tensile strength of 980-1150 MPa, and an elongation of 17-25%.2. The high-formability and ultra-high-strength steel plate of claim 1 , wherein carbon is present in an amount ranging from 0.18-0.22 wt %.3. The high-formability and ultra-high-strength steel plate of claim 1 , wherein silicon is present in an amount ranging from 1.4-1.8 wt ...

POWER SEMICONDUCTOR DEVICES

A power semiconductor device includes a diode part disposed in a first region of a substrate, a junction field effect transistor (JFET) part disposed in a second region adjacent to the first region of the substrate, an anode terminal disposed on the first region of the substrate, and a cathode terminal disposed on the second region of the substrate. 1. A method , comprising:implanting a lower barrier region of a first conductivity type in a diode part of a base substrate and a lower layer of the first conductivity type in a junction field effect transistor (JFET) part adjacent to the diode part of the base substrate;implanting a buried layer of the first conductivity type between the lower barrier region in the diode part and the lower layer in the JFET part;forming a semiconductor layer on the base substrate;diffusing a portion of the buried layer of the first conductivity type into the semiconductor layer;forming an anode terminal in the diode part; andforming a cathode terminal in the JFET part.2. The method of claim 1 , further comprising:forming a body region in the diode part, the diode part has an upper portion connected with the anode terminal.3. The method of claim 2 , further comprising:forming a well on one side of the body region, the well having a first impurity concentration, the well having an upper portion of a sidewall surrounding the body region.4. The method of claim 3 , wherein a bottom of the body region is positioned at a higher level than a bottom of the well.5. The method of claim 1 , further comprising:forming a body region in the diode part;forming a well on one side of the body region; andforming a semiconductor region disposed below the body region, the well having a lower portion of a sidewall surrounding the semiconductor region.6. The method of claim 1 , further comprising:forming a well having a bottom of the well in contact with a top of the lower barrier region.7. The method of claim 1 , further comprising:forming a body region in ...

CHIP PACKAGE UNIT AND CHIP PACKAGING METHOD

A chip package unit includes: a base material; at least one chip, disposed on the base material; a package material, enclosing the base material and the chip; and at least one heat dissipation paste curing layer, formed by curing the heat dissipation paste, on a top side of the package material or a back side of the chip in a printed pattern.

New Process

Preparation of tert-butyl 4-((1r,2s,5r)-6- (benzyloxy)-7-0x0-1,6-diazabicycl0[3.2.i]octane-2- carboxamido)piperidine-1-carboxylate

Systems and methods for increasing the efficiency of low pressure axial fans

A system for increasing the efficiency of low pressure axial fans, includes, a low pressure axial fan including multiple first blades, and, a vortex generator operably coupled to the low pressure axial fan via a shaft. In use, the vortex generator includes multiple second blades. In further use, the low pressure axial fan is configured to operate in an operational mode and the vortex generator is configured to operate in a stationary mode.

Crystalline forms of cgrp receptor antagonists

The invention is directed to a Crystalline hydrate of ( S )- N -((3 S ,5 S ,6 R )-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide and a crystalline form of ( S )- N -((3 S ,5 S ,6 R )-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,5-trifluorophenyl)piperidin-3-yl)-2'-oxo-l',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide.

Methods and intermediates for preparing macrolactams

Use of tyrphostins to stimulate neurite outgrowth

Disclosed herein are several methods for promoting nerve regeneration. The methods include administering at least one tyrphostin, or a pharmaceutically acceptable salt thereof. In one non-limiting example, the tyrphostin is tyrphostin A9. These methods can be used to promote nerve growth in the central or peripheral nervous system. The methods are of use in treating neurodegenerative diseases, such as Parkinson's disease, or in treating the transaction of a partial or complete transaction of a nerve in the peripheral or central nervous system.

Hot dipped high manganese steel and manufacturing method therefor

A hot dipped high manganese steel and a manufacturing method therefor. The high manganese steel comprises a steel base plate and a coating on the surface of the steel base plate. The core of the steel base plate is austenite. The surface layer of the steel base plate is a ferrite fine grain layer. The ferrite fine grain layer comprises an oxide of Al. Furthermore, the steel base plate of the hot dipped high manganese steel comprises, in mass percentages, 10 to 30% of Mn element, 1 to 2% of Al element, and 0.4 to 0.8% of C element. The manufacturing method comprises: 1) manufacturing strip steel; 2) primary annealing and acid washing; 3) secondary annealing and hot dipping.

Method and device for data transmission

Compounds, compositions containing them, preparation thereof and uses thereof iii

Compounds of Formula I, or pharmaceutically acceptable salts thereof: I (chemical formula to be inserted here - please see paper copy) wherein R1, R2, R3, R4, R5, R6 and G are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

Heat dissipation device with a heat pipe

Hot dipped high manganese steel and manufacturing method therefor

A hot dipped high manganese steel and a manufacturing method therefor. The high manganese steel comprises a steel base plate and a coating on the surface of the steel base plate. The core of the steel base plate is austenite. The surface layer of the steel base plate is a ferrite fine grain layer. The ferrite fine grain layer comprises an oxide of Al. Furthermore, the steel base plate of the hot dipped high manganese steel comprises, in mass percentages, 10 to 30% of Mn element, 1 to 2% of Al element, and 0.4 to 0.8% of C element. The manufacturing method comprises: 1) manufacturing strip steel; 2) primary annealing and acid washing; 3) secondary annealing and hot dipping.

Process for making cgrp receptor antagonists

The disclosure encompasses a novel process for making piperidinone carboxamide indane and azainane derivatives, having less steps and improved yields as compared to previous synthetic methods for making these compounds, which are CGRP receptor antagonists, useful for the treatment of migrane. Conditions for an amide bond formation between an acid and amine include for example reacting the compounds of Formulae B (after salt break) and C with an amide coupling reagent and optionally an additive and an acid and/or a base in a non-reactive solvent.

Method for manufacturing hot-dip galvanized steel sheet, and steel sheet and vehicle component

The present invention provides a method for manufacturing a hot-dip galvanized steel sheet, comprising performing a heat treatment step, a hot dip plating step, and an alloying treatment step on a steel sheet having high Si and Mn content. The heat treatment step comprises a first heating phase and a soaking phase; a first heating atmosphere of the first heating stage contains 0.01-0.5% of O2 by volume, and the balance is N2 and inevitable impurities; a soaking atmosphere of the soaking stage contains 0.5% or more of H2 by volume, and the balance is N2 and inevitable impurities; dew points of the first heating atmosphere and the soaking atmosphere are controlled to be greater than or equal to -20°C. The present invention further provides a hot-dip galvanized steel sheet and a vehicle component. According to the present invention, by controlling the heat treatment atmospheres, the enrichment of Si and Mn alloy elements on the surface of the steel sheet, an interface between iron oxide and a base steel sheet, and an interface between reduced iron and the base steel sheet is suppressed, so that when a steel sheet having high Si and Mn content is selected as a base material for the hot-dip galvanized steel sheet, after undergoing the alloying treatment step, the hot-dip galvanized steel sheet can have both a plating layer of sufficient Fe content and a high elongation at break rate.

New process for the preparation of morphinans

A process for the preparation of 14-alkoxyindolomorphinans and 14-alkoxybenzofuranomorphinans is disclosed. The process facilitates the preparation of a large variety of 14-alkoxy substituted indolomorphinans and benzofuranomorphinans in which a 3-hydroxy substituent is present.

Screwdriver

High-formability and super-strength cold-rolled steel sheet and manufacturing method thereof

Electronic device

The present disclosure provides an electronic device. The electronic device comprises a metal case, a slot antenna, a first dielectric material and a second dielectric material. The slot antenna is provided in the metal case and generates a signal. A dielectric constant of the second dielectric material is greater than a dielectric constant of the first dielectric material. The slot antenna comprises an electrical conductive member. The electrical conductive member is configured to define a slot which is closed at two ends thereof, the first dielectric material and the second dielectric material is provided in the slot, wherein the slot has a length, the length and the first dielectric material together determine that a high frequency band of the signal conforms to a high frequency band of a WIFI protocol, and the length and the first dielectric material together determine that a low frequency band of the signal is greater than a low frequency band of the WIFI protocol. The second dielectric material lowers the low frequency band of the signal to be within the low frequency band of the WIFI protocol. Because the second dielectric material is used, even if the slot antenna is positioned in the metal case, the slot antenna is still capable of generating a WIFI signal having two frequency bands.

High-formability and super-strength cold-rolled steel sheet and manufacturing method thereof

A high-formability and super-strength cold-rolled steel sheet and a manufacturing method thereof. The weight percentage of its components is: C 0.15~0.25%, Si 1.00~2.00%, Mn 1.50~3.00%, P=0.015%, S=0.012%, Al 0.03~0.06%, N=0.008%, and the rest are Fe and inevitable impurities. The manufacturing method comprises the following steps: 1) smelting and casting; 2) heating to 1170~1230°C and performing thermal insulation; 3) performing hot rolling, the finish rolling temperature being 880±30°C, and coiling at 550~650°C; and 4) performing acid washing, cold rolling, and annealing, the cold rolling reduction being 40~60%, annealing at 860~920°C, and performing slow cooling to 690~750°C with the cooling rate of 3~10°C/s; performing rapid cooling at 240~320°C, with the cooling rate =50°C/s, then heating to 360~460°C, and performing thermal insulation for 100~500s to cool to the room temperature at last. Finally, a high-formability, low-rebound property and super-strength cold-rolled steel sheet with the yield strength of 600~900MPa, the tensile strength of 980~1150MPa, the elongation of 17~25% is obtained.

Process for making CGRP receptor antagonists

The invention encompasses a novel process for making piperidinone carboxamide indane and azainane derivatives, which are CGRP receptor antagonists useful for the treatment of migraine.

Cannabinoid receptor ligands

Compounds of Formulae (I), or pharmaceutically acceptable salts thereof: wherein R1, R2 and Y are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

Preparation of tert-butyl 4-((1r,2s,5r)-6- (benzyloxy)-7-0x0-1,6-diazabicycl0[3.2.i]octane-2- carboxamido)piperidine-1-carboxylate

A process for the preparation of N-protected 6-(piperidin-4-ylcarbamoyl)piperidin-3-yl sulfonates of Formula (III): which comprises contacting a lactone of Formula (II): with an azacycloalkylamine of formula (II-Am): followed by contact with a sulfonyl halide of formula (II-Su): R 4 -SO 2 W (II-Su) in the presence of tertiary amine base, wherein P G1 and P G2 are amine protective groups; k, p and q are 0, 1, or 2, and W, R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , and R 9 are defined herein. Additional embodiments add a series of process steps leading to the synthesis of 7-oxo-1,6-diazabicyclo[3.2.1]octanes suitable for use as β-lactamase inhibitors.

Wall-mounted type tri-outlets hybrid faucet structure

Cannabinoid receptor ligands

Compounds of Formulae (I), or pharmaceutically acceptable salts thereof: wherein R1, R2 and Y are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

Reflecting assembly, backlight module and display device having the backlight module

一種背光模組及其反射元件，該背光模組包含複數相間隔地排列設置的光學透鏡、複數分別設置於該等光學透鏡的發光元件、一具有一入光面與一出光面的光學板，及一反射元件。該反射元件包括複數相互鄰接的環體部，每一環體部是圍繞相對應的一個光學透鏡設置，且每一環體部的高度是不大於相對應的一個光學透鏡之高度，每一發光元件經由各別的光學透鏡所射出的一部分光線是進入該光學板的該入光面，再由該光學板的該出光面射出，另一部分的光線是被各別的環體部所反射再進入該光學板的該入光面，再由該光學板的該出光面射出，提高整體出光均勻度。

Content sharing for mobile devices

Aspects of the subject matter described herein relate to content sharing for mobile devices. In aspects, images that are created using mobile devices may be automatically uploaded to one or more targets. In addition, images created on the one or more targets may be automatically downloaded to the mobile device based on one or more criteria. A service facilitates transfer of images in both directions and includes a pluggable architecture in which forwarders for new targets may be added.

Preparation of tert-butyl 4-((1r,2s,5r)-6- (benzyloxy)-7-0x0-1,6-diazabicycl0[3.2.i]octane-2- carboxamido)piperidine-1-carboxylate

A process for the preparation of N-protected 6-(piperidin-4-ylcarbamoyl)piperidin-3-yl sulfonates of Formula (III): which comprises contacting a lactone of Formula (II): with an azacycloalkylamine of formula (II-Am): followed by contact with a sulfonyl halide of formula (II-Su): R 4 -SO 2 W (II-Su) in the presence of tertiary amine base, wherein P G1 and P G2 are amine protective groups; k, p and q are 0, 1, or 2, and W, R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , and R 9 are defined herein. Additional embodiments add a series of process steps leading to the synthesis of 7-oxo-1,6-diazabicyclo[3.2.1]octanes suitable for use as β-lactamase inhibitors.

Backlight module and display device

A sol-gel route for nano sized lifepo4/c for high performance lithium ion batteries

This invention relates to a novel a sol-gel method of synthesizing uniformly carbon-coated LiFeP0 4 (LiFeP0 4 /AS). The method including the steps of: mixing a lithium source a phosphoric source and a carbon source with a solution containing Fe ions to form a gel; and calcining the gel to provide uniformly carbon-coated LiFeP0 4 (LiFePO 4 /AS). According to the invention, the phosphoric source is a phosphonic acid.

Process for making beta 3 agonists and intermediates

The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.

Schottky diode structure

Carbazole derived compounds, cb1 receptor binder; pharmaceutical composition comprising them; process of preparing these; and uses in the treatment of cancer, multiple sclerosis, Parkinson's, GI and cardiovascular disorders, among others.

Compuestos derivados de carbazol hidrogenados; procedimiento de preparación; composición farmacéutica; y su uso en el tratamiento del dolor, trastornos de ansiedad, cáncer, esclerosis múltiple, enfermedad de Parkinson, corea de Huntington, Alzheimer, trastornos gastrointestinales, trastornos cardiovasculares, entre otras. Hydrogenated Carbazole Derived Compounds; preparation procedure; pharmaceutical composition; and its use in the treatment of pain, anxiety disorders, cancer, multiple sclerosis, Parkinson's disease, Huntington's chorea, Alzheimer's, gastrointestinal disorders, cardiovascular disorders, among others.

Methods and compositions for producing microlenses and optical filters

The invention relates to novel vitreous microlenses and optical filters and methods for their formation. This includes formation of inorganic oxide microlenses and optical filters on other objects, including the production of oxide glasses in various shapes. For example, the present invention is directed to the use of precursor materials such as carboxylated polysiloxanes, including carboxylated polygermanosiloxanes in the hydrogen or fully or partially metal ion exchanged forms to produce the vitreous microlenses and optical filters of the invention.

Radio link monitoring and cell search techniques for high movement speeds

This disclosure relates to techniques for performing radio link monitoring and cell searching when moving at high speeds. A movement speed of a wireless device may be determined. When performing a cell search, the manner of the cell search may depend on the movement speed of the wireless device, potentially including cells that are associated with high movement speed being more highly prioritized when the wireless device is determined to be at a higher movement speed than when the wireless device is determined to be at a lower movement speed.

Compounds, compositions containing them, preparation thereof and uses thereof iii

Compounds of Formula I, or pharmaceutically acceptable salts thereof: I (chemical formula to be inserted here - please see paper copy) wherein R1, R2, R3, R4, R5, R6 and G are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

DERIVATIVES OF 2,3,4,9-TETRAHYDRO-1H-CARBAZOLE AS LIGANDS OF THE CB1 RECEPTOR

REFERIDA A COMPUESTOS DERIVADOS DE 2,3,4,9-TETRAHIDRO-1H-CARBAZOL DE FORMULA (I) DONDE Y ES (a), (b), (c), ENTRE OTROS, EN DONDE R3 Y R4 SON CADA UNO H, AMINO, -C(=O)-O-ALQUILO(C1-C6), ENTRE OTROS; R5 ES H, ALQUILO(C1-C6) O CICLOALQUILO(C3-C6); R6 ES H, CN, NO2, NH2, ALCOXI(C1-C6), ENTRE OTROS; Q ES ALQUILENO(C1-C6), ALQUILIDENO(C1-C6), ENTRE OTROS; m ES DE 0 A 3; n ES DE 1 A 3; R1 ES H, ALQUILO(C1-C6), CICLOALQUILO(C3-C6), -S(=O)2-ALQUILO(C1-C6), ENTRE OTROS; R2 ES HETEROCICLOALQUILO(C3-C6), HETEROCICLOALQUIL(C3-C6)-ALQUILO(C1-C4), ARILO(C6-C10), ENTRE OTROS. SON COMPUESTOS PREFERIDOS: N-[2-(CICLOPROPILAMINO)-2-OXOETIL]-N,9-DIMETIL-3-(TETRAHIDRO-2H-PIRAN-4-IL)-2,3,4,9-TETRAHIDRO-1H-CARBAZOL-6-CARBOXAMIDA, N-ETIL-N-[2-(ETILAMINO)-2-OXOETIL]-9-METIL-3-(TETRAHIDRO-2H-PIRAN-4-IL)-2,3,4,9-TETRAHIDRO-1H-CARBAZOL-6-CARBOXAMIDA, N-CICLOPROPIL-2-(1-(9-METIL-3-(TETRAHIDRO-2H-PIRAN-4-IL)-2,3,4,9-TETRAHIDRO-1H-CARBAZOL-6-CARBONIL)AZETIDIN-3-IL)ACETAMIDA, ENTRE OTROS. SE REFIERE TAMBIEN A UN PROCEDIMIENTO DE PREPARACION Y A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON LIGANDOS DEL RECEPTOR CANNABINOIDE CB1 SIENDO UTILES EN EL TRATAMIENTO DEL DOLOR, ESCLEROSIS MULTIPLE, COREA HUNTINGTON, ENFERMEDAD DE ALZHEIMER REFERRING TO COMPOUNDS DERIVED FROM 2,3,4,9-TETRAHIDRO-1H-CARBAZOL DE FORMULA (I) WHERE AND IS (a), (b), (c), AMONG OTHERS, WHERE R3 AND R4 ARE EACH H , AMINO, -C (= O) -O-ALKYL (C1-C6), AMONG OTHERS; R5 IS H, (C1-C6) ALKYL OR (C3-C6) CYCLOALKYL; R6 IS H, CN, NO2, NH2, ALCOXY (C1-C6), AMONG OTHERS; Q IS ALKYLENE (C1-C6), ALKYLIDENE (C1-C6), AMONG OTHERS; m IS 0 TO 3; n IS FROM 1 TO 3; R1 IS H, ALKYL (C1-C6), CYCLOALKYL (C3-C6), -S (= O) 2-ALKYL (C1-C6), AMONG OTHERS; R2 IS HETERO CYCLOALKYL (C3-C6), HETERO CYCLOALKYL (C3-C6) -ALKYL (C1-C4), ARYL (C6-C10), AMONG OTHERS. THE PREFERRED COMPOUNDS ARE: N- [2- (CYCLOPROPYLAMINO) -2-OXOETHYL] -N, 9-DIMETHYL-3- (TETRAHYDRO-2H-PYRAN-4-IL) -2,3,4,9-TETRAHYDRO-1H- CARBAZOL-6-CARBOXAMIDE, N-ETHYL-N- [2- (ETHYLAMINE) -2- ...

Methods and compositions for nerve regeneration

A method of promoting nerve regeneration in a subject that includes administering to the subject a therapeutically effective amount of a composition that includes at least one therapeutically-active extract fraction of Centella asiatica. One example of making the extract fraction of Centella asiatica involves extracting Centella asiatica plant material resulting in an extract residue and successively fractionating the Centella asiatica extract residue with at least two eluants of increasing polarity.

Hyperfine coupling bridged resonant DND enhancement method

Cmos power oscillator with frequency modulation

CMOS power oscillator and a method of frequency modulating a CMOS power oscillator. The oscillator comprises a transformer-based feedback CMOS power oscillator circuit formed on a chip-substrate, the oscillator circuit including a transformer coupled to a transistor; means for modulating the capacitance of the transformer to the chip-substrate for frequency modulating an output of the power oscillator.

Antenna device

An antenna device includes an insulating carrier and a first primary antenna having a first feeding-in section, a first auxiliary antenna having a second feeding-in section and a second grounding section, a second primary antenna having a third feeding-in section, a second auxiliary antenna having a fourth feeding-in section and a grounding face which are provided on a face of the carrier. The first primary and auxiliary antennas and the second primary and auxiliary antennas are positioned at two side edges of the carrier which are away from each other. The grounding face is positioned between both the first primary and auxiliary antennas and the second primary and auxiliary antennas. The grounding face is provided with a first grounding section adjacent to the first feeding-in section, a third grounding section adjacent to third feeding-in section and a fourth grounding section adjacent to the fourth feeding-in section.

Benzimidazole 5-sulfonamide derivatives as cannabinoid 1 (cb1) receptor ligands

Compounds of formula I or pharmaceutically acceptable salts thereof: [Chemical formula should be inserted here. Please see paper copy] I wherein R1, R2, R3 and R4 are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

Variable-gain cascode amplifier using voltage-controlled and variable inductive load

Circuits, such as a cascode amplifier or low noise amplifier, having terminals and a voltage-controlled and variable inductive load are disclosed. Any such circuit comprises an output terminal and a voltage-controlled and variable inductive loading network. The voltage-controlled and variable inductive loading network comprises a primary inductor having a first primary inductor terminal for coupling to a supply voltage, a second primary inductor terminal coupled to the output terminal, a secondary inductor sharing mutual inductance with the first inductor, and a variable resistance device having one terminal connected to a first secondary inductor terminal and another terminal connected to a second secondary inductor terminal, wherein the variable resistance device being dependant on mutual induction between the primary and secondary inductors provides loading at the output terminal.

Native nmos device and manufacturing method thereof

A native NMOS device includes: a P-type epitaxial layer, a first and a second insulation region, a first P-type well, a second P-type well, a gate, an N-type source, and an N-type drain. The P-type epitaxial layer has a first concentration of P-type doped impurities. The first P-type well completely encompasses and is in contact with a lower surface of the N-type source. The second P-type well completely encompasses and is in contact with a lower surface of the N-type drain. Each of the first P-type well and the second P-type well has a second concentration of P-type doped impurities, and the second concentration of P-type doped impurities is higher than the first concentration of P-type doped impurities. The second concentration of P-type doped impurities is sufficient for preventing a leakage current from flowing between the N-type drain and the P-type substrate while the native NMOS device is in operation.

Method for manufacturing hot-dip galvanized steel sheet, and steel sheet and vehicle component

The present invention provides a method for manufacturing a hot-dip galvanized steel sheet, comprising performing a heat treatment step, a hot dip plating step, and an alloying treatment step on a steel sheet having high Si and Mn content. The heat treatment step comprises a first heating phase and a soaking phase; a first heating atmosphere of the first heating stage contains 0.01-0.5% of O2 by volume, and the balance is N2 and inevitable impurities; a soaking atmosphere of the soaking stage contains 0.5% or more of H2 by volume, and the balance is N2 and inevitable impurities; dew points of the first heating atmosphere and the soaking atmosphere are controlled to be greater than or equal to −20° C. The present invention further provides a hot-dip galvanized steel sheet and a vehicle component. According to the present invention, by controlling the heat treatment atmospheres, the enrichment of Si and Mn alloy elements on the surface of the steel sheet, an interface between iron oxide and a base steel sheet, and an interface between reduced iron and the base steel sheet is suppressed, so that when a steel sheet having high Si and Mn content is selected as a base material for the hot-dip galvanized steel sheet, after undergoing the alloying treatment step, the hot-dip galvanized steel sheet can have both a plating layer of sufficient Fe content and a high elongation at break rate.