Crossing method for performing label mapping based on HASH

The invention relates to a crossing method for performing label mapping based on HASH. The crossing method comprises the following steps of; 1, generating a correspondence table for MAC addresses and HASHES of all ENTRIES, wherein the initial states of all the ENTRIES are idle states; 2, distributing an idle ENTRY to each new service, and selecting the corresponding unicast or multicast MAC address in the ENTRY content as a mapping address for the service, wherein the state of the ENTRY is changed into an on state after the distribution; 3, performing the label mapping by a TUNNEL MAP chip by using the distributed MAC address and setting an L2 address table by an MAC crossing chip by using the MAC address; and 4, releasing the ENTRY and assigning the state to be the idle state when the crossing service is deleted. The method of the invention absolutely solves the crossing limitation caused by HASH collision, and the number of the crossed entries is completely equal to the physical capacity ...

一种语言信箱系统和录放音方法

The phonetic system separates the data processing part from storage management part, and changes the speech sound card based on computer to the speech sound card based on digital program control exchanger. The system comprises the digital program control exchanger, multiple speech sound cards, background storage server for speech sound, and mass memory unit. When recording, data through the digital program control exchanger reaches to the speech sound card, and then transferred to background storage server for speech sound, and mass memory unit. When playing, the background storage server for speech sound completes playing according to real time data of speech sound from the speech sound card with path marked by speech sound in mail.

Natural gas liquefying device based on low-temperature liquid refrigeration

The invention provides a natural gas liquefying device based on low-temperature liquid refrigeration, mainly comprising a main heat exchanger, a natural gas throttling refrigeration unit and a low-temperature liquid refrigerating unit. The natural gas liquefying device based on low-temperature liquid refrigeration is characterized by adopting the latent heat and the sensible heat of low-temperature liquid gasification as cold sources for cooling, liquefying and supercooling natural gas in the low-temperature liquid refrigerating unit, thereby lowering or eliminating the evaporating rate of the liquefied natural gas, reducing the technical requirement on the filling equipment and operation and realizing large refrigerating capacity and the natural gas liquefaction circulation with the remotely separated refrigeration and liquefaction.

Multi-unmanned aerial vehicle autonomous coverage method based on pheromone inspiration

The invention relates to a multi-unmanned aerial vehicle autonomous coverage method based on pheromone inspiration. The method comprises the following steps: step S1, constructing a coverage scene graph of natural disaster area data autonomously collected by multiple unmanned aerial vehicles; s2, based on the pheromone aggregation model, constructing a multi-unmanned aerial vehicle path pheromone map, and marking multi-unmanned aerial vehicle paths; s3, according to the multi-unmanned aerial vehicle autonomous coverage task, defining a state function, an action function and a reward function, establishing a multi-unmanned aerial vehicle autonomous coverage model based on a neural network, and performing training; and S4, performing multi-unmanned aerial vehicle autonomous coverage by adopting the trained multi-unmanned aerial vehicle autonomous coverage model. Compared with the prior art, the method has the advantages of high efficiency, energy conservation, high coverage rate and wide ...

SUBSTITUTED PYRIMIDINYL-AMINES AS PROTEIN KINASE INHIBITORS

The present invention provides novel substituted pyrimidinyl-amines that are useful as inhibitors of protein kinases, especially c-Jun N-terminal kinases (JNK) and pharmaceutical compositions thereof and methods of using the same for treating conditions responsive to the inhibition of the JNK pathway. More particularly, the present invention relates to a compound or pharmaceutically acceptable salt thereof of formula lb: (see formula Ib) ...

SUBSTITUTED PROLINES / PIPERIDINES AS OREXIN RECEPTOR ANTAGONISTS

The present invention is directed to compounds that can modulate the bioactivity of an orexin receptor such as OX1 or OX2, or both; to pharmaceutical compositions and combinations comprising a compound of the invention; to methods of treatment of malconditions in patients wherein modulation of an orexin receptor is medically indicated; and to methods of preparation of compounds of the invention.

STABLE AND ION-CONDUCTIVE FLUOROPOLYMER-BASED ELECTROLYTES

Novel fluorocarbon polymers with a heteroaromatic group or a HPCA group are disclosed. A protonated fluoropolymer with a heteroaromatic group can be used as a cation-conductive electrolyte while an HPCA-based fluoropolymer encapsulating a H or Li can be employed as anion-transporting electrolyte. 133-. (canceled)35. The fluorocarbon polymer of claim 34 , wherein Ris F; n is 1; —Z— is a direct bond claim 34 , —CF— claim 34 , or —CFCF—; Rand Rare both H; and E and Q are either of the following: (a) E is N and Q is CH or (b) E is CH and Q is N.36. The fluorocarbon polymer of claim 34 , wherein Ris CF; n is 1 or 2; —Z— is —OCFCF—; Rand Rare H; and E and Q are either of the following: (a) E is N and Q is CH or (b) E is CH and Q is N.38. The fluorocarbon polymer of claim 37 , wherein Ris F claim 37 , n is 1; —Z— is a direct bond claim 37 , —CF— claim 37 , or —CFCF—; both Rand Rare H; E and Q are either of the following: (a) E is N and Q is CH or (b) E is CH and Q is N; and x ranges from 0.35 to 0.92.39. A composite comprising the fluorocarbon polymer of and HX claim 38 , wherein n′ is an integer number chosen from 1 claim 38 , 2 claim 38 , 3 claim 38 , 4 claim 38 , or 5; Xis a negatively charged anion; and the concentration of HXranges from 4 to 70 wt % by weight of the composite.40. The composite of claim 39 , wherein HXis either HSOor HPO; and the concentration of HXranges from 4 to 20 wt % by weight of the composite.41. The fluorocarbon polymer of claim 37 , wherein Ris CF; n is 1 or 2; —Z— is —OCFCF—; Rand Rare H; E and Q are either of the following: (a) E is N and Q is CH or (b) E is CH and Q is N; and x ranges from 0.65 to 0.92.42. A composite comprising the fluorocarbon polymer of and HX claim 41 , wherein n′ is an integer number chosen from 1 claim 41 , 2 claim 41 , 3 claim 41 , 4 claim 41 , or 5; Xis a negatively charged anion; and the concentration of HXranges from 4 to 70 wt % by weight of the composite.43. The composite of claim 42 , wherein HXis HSO; n′ is 2; ...

Biological feed additive and its preparing process

A biological additive of feed is prepared through screening to obtain green lactobacterium, coprophilous lactobacterium, yeast and hay bacillus, the first culture, the second culture, adsorbing the bacterial liquid by rice or wheat bran, stacking fermentation and baking. It can improve the function of digestive system and quality of animal products, increase the being assimilated and transform rate of feed, and reduce feed cost.

Heat treatment process of steel ball matched with special motor precision bearing

The invention provides a heat treatment process for a steel ball matched with a special motor precision bearing. The heat treatment process comprises the following steps: S1, quenching; s2, subzero treatment is conducted; s3, primary tempering; s4, strengthening; and S5, secondary tempering is conducted. The invention provides a heat treatment process of a steel ball matched with a special motor precision bearing. The heat treatment process comprises five steps of quenching, subzero treatment, primary tempering, strengthening and secondary tempering. Subzero treatment is carried out after quenching, and the hardness and wear resistance of the steel ball can be improved through the subzero treatment process; the residual austenite is reduced to the maximum extent, the structure of the steel ball is stabilized, and the situation that in the using process, due to creep deformation of the residual austenite and instability of the size (the change value exceeds the standard after year), the ...

Substituted prolines/piperidines as orexin receptor antagonists

The present invention is directed to compounds that modulate the bioactivity of an orexin receptor such as OX1 or OX2, or both; to pharmaceutical compositions and combinations comprising a compound of the invention; to methods of treatment of malconditions in patients wherein modulation of an orexin receptor is medically indicated; and to methods of preparation of compounds of the invention. For example, orexin receptor-modulatory compounds of the present invention can be used in treatment of an eating disorder, obesity, alcoholism or an alcohol-related disorder, drug abuse or addiction including addiction to cocaine, opiates, amphetamines, or nicotine, a sleep disorder, a cognitive dysfunction in a psychiatric or neurologic disorder, depression, anxiety, panic disorder, schizophrenia, Alzheimer's disease, Parkinson's disease, Huntington's chorea, headache, migraine, pain, gastrointestinal diseases, epilepsy, inflammations, immune-related diseases, endocrine-related diseases, cancer, hypertension ...

Intelligent cotton harvester

The invention discloses a cotton intelligent picking harvester, pertaining to the technical field of agricultural engineering. The harvester comprises a self-propelled chassis, a picking manipulator device, an aspiration fan device, a cotton box, an engine, an image collection device, an image analysis recognition and control system, a storage battery, an end effector, etc. The invention collects cotton images through the image collection device and judges whether the cotton is ripe or not by the analysis and treatment of the image analysis recognition and control system, then sends orders to the picking manipulator device, the aspiration fan device or the self-propelled chassis and makes the picking manipulator device, the aspiration fan device or the self-propelled chassis move, pick or walk according to the orders, thereby, the cotton intelligent picking harvester can complete the cotton picking and harvest through the working process.

Structure and method for improving the cross entry of T-MPLS equipment by using label mapping

A structure and a method for improving the cross entry of T-MPLS equipment by using label mapping relate to a T-MPLS technology and a cross structure, comprise a cross matrix CROSS, and are characterized in that the cross matrix CROSS comprises a large-capacity DMAC cross chip, a plurality of TUNNEL MAP chips and a plurality of branch chips Ts; a many-to-one or one-to-one relationship exists between the branch chips Ts and the TUNNEL MAP chips; a many-to-one relationship exists between the TUNNEL MAP chips and the DMAC cross chip; and a one-to-many relationship exists between the DMAC cross chip and the branch chips Ts. The structure and the method for improving the cross entry of the T-MPLS equipment by using label mapping utilize the existing chip technology to conduct resource re-mapping and carry out resource integration to the chips of different technologies so as to construct a large-capacity cross matrix, thereby achieving the purpose of improving the cross entry of the T-MPLS equipment ...

User-meter relation identification method and identification device

The invention relates to the technical field of user meter identification, in particular to a user meter identification method and an identification device. The method comprises the following steps: acquiring electric meter power of a plurality of test users before testing, acquiring electric meter power of load users in a classified manner after loads occur in different user houses, and acquiring electric meter power of the test users after the loads are withdrawn after the loads are withdrawn. Whether a plurality of user-meter relations are correct or not is simultaneously determined through the power changes of the electric meters before, during and after the test. Load in a user home is generated through the test terminal, electricity meter power of a user is read through the management terminal, and correctness of user-meter relation is judged through the master station system. The method is simple in composition and convenient to use, the multiple test terminals and the multiple management ...

Pedestrian crossing intelligent street lamp indication system based on millimeter wave radars and control method

The invention provides a pedestrian crossing intelligent street lamp indication system based on millimeter wave radars and a control method. A plurality of pedestrian indicating lamp units are arranged on a pedestrian crossing in the length direction of a pedestrian crossing, whether pedestrians are close to the pedestrian indicating lamp units or not is detected through millimeter-wave radars arranged in the pedestrian indicating lamp units, and the pedestrian indicating lamp units are turned on when pedestrians are close to the pedestrian indicating lamp units and turned off when no pedestrians are close to the pedestrian indicating lamp units. In this manner, when a pedestrian passes through the pedestrian crossing, the pedestrian indicating lamp units where pedestrians are going to pass through on the area are all turned on, and the pedestrian indicating lamp units in the area where no pedestrian is going to pass through are not lightened, thus a motor vehicle driver is reminded ofpaying ...

Application of reagent for detecting circALMS1 in preparation of product for predicting onset risk of IPAH or COPD-PH patient

The invention provides application of a reagent for detecting circALMS1 in preparation of a product for predicting the onset risk of a patient suffering from idiopathic pulmonary hypertension (IPAH) or chronic obstructive pulmonary disease related pulmonary hypertension (COPD-PH). According to the invention, it is found for the first time that plasma circALMS1 expression levels of IPAH and COPD-PH patients and normal control persons are different, the plasma circALMS1 can be used as an independent onset risk prediction factor, and a reference is provided for assessment of disease onset and clinical prevention and treatment of the IPAH and COPD-PH patients.

Bio-based water-based acrylic acid hydrogel and preparation method thereof

The invention discloses a bio-based water-based acrylic hydrogel and a preparation method thereof, and belongs to the technical field of adhesives, and the preparation method comprises the following steps: (1) adding an acrylic monomer, polyvinyl alcohol, alpha-ketoglutaric acid and a modified nanocellulose dispersion liquid into a sulfuric acid solution with the concentration of 1 mol/L, and magnetically stirring to fully mix to obtain a template solution; (2) injecting the template solution into a glass plate mold, irradiating for 6 hours under ultraviolet light with the wavelength of 365 nm, then freeze-drying for 12 hours at the temperature of-20 DEG C to-30 DEG C, and unfreezing at room temperature to obtain bio-based water-based acrylic acid hydrogel; the polyvinyl alcohol and the modified nanocellulose are added into the acrylic monomer, and polymerization is initiated by ultraviolet light, so that the prepared bio-based water-based acrylic hydrogel not only has no toxicity and is ...

SUBSTITUTED PYRIMIDINYL-AMINES AS PROTEIN KINASE INHIBITORS

The present invention provides novel substituted pyrimidinyl-amines that are useful as inhibitors of protein kinases, especially c-Jun N-terminal kinases (JNK) and pharmaceutical compositions thereof and methods of using the same for treating conditions responsive to the inhibition of the JNK pathway.

Substituted prolines / piperidines as orexin receptor antagonists

The present invention is directed to compounds that can modulate the bioactivity of an orexin receptor such as OX1 or OX2, or both; to pharmaceutical compositions and combinations comprising a compound of the invention; to methods of treatment of malconditions in patients wherein modulation of an orexin receptor is medically indicated; and to methods of preparation of compounds of the invention.

Substituted prolines / piperidines as orexin receptor antagonists

The present invention is directed to compounds that modulate the bioactivity of an orexin receptor such as OX1 or OX2, or both; to pharmaceutical compositions and combinations comprising a compound of the invention; to methods of treatment of malconditions in patients wherein modulation of an orexin receptor is medically indicated; and to methods of preparation of compounds of the invention. For example, orexin receptor-modulatory compounds of the present invention can be used in treatment of an eating disorder, obesity, alcoholism or an alcohol-related disorder, drug abuse or addiction including addiction to cocaine, opiates, amphetamines, or nicotine, a sleep disorder, a cognitive dysfunction in a psychiatric or neurologic disorder, depression, anxiety, panic disorder, schizophrenia, Alzheimer's disease, Parkinson's disease, Huntington's chorea, headache, migraine, pain, gastrointestinal diseases, epilepsy, inflammations, immune-related diseases, endocrine-related diseases, cancer, hypertension ...

SUBSTITUTED PROLINES / PIPERIDINES AS OREXIN RECEPTOR ANTAGONISTS

The present invention is directed to compounds that modulate the bioactivity of an orexin receptor such as OXor OX, or both; to pharmaceutical compositions and combinations comprising a compound of the invention; to methods of treatment of malconditions in patients wherein modulation of an orexin receptor is medically indicated; and to methods of preparation of compounds of the invention. For example, orexin receptor-modulatory compounds of the present invention can be used in treatment of an eating disorder, obesity, alcoholism or an alcohol-related disorder, drug abuse or addiction including addiction to cocaine, opiates, amphetamines, or nicotine, a sleep disorder, a cognitive dysfunction in a psychiatric or neurologic disorder, depression, anxiety, panic disorder, schizophrenia, Alzheimer's disease, Parkinson's disease, Huntington's chorea, headache, migraine, pain, gastrointestinal diseases, epilepsy, inflammations, immune-related diseases, endocrine-related diseases, cancer, hypertension, behavior disorder, mood disorder, manic depression, dementia, sex disorder, psychosexual disorder, or renal disease. 3. The compound of claim 1 , wherein Hetis pyrrolyl claim 1 , pyrazolyl claim 1 , imidazolyl claim 1 , oxazolyl claim 1 , isoxazolyl claim 1 , thiazolyl claim 1 , isothiazolyl claim 1 , oxadiazolyl claim 1 , thiadiazolyl claim 1 , triazolyl claim 1 , tetrazolyl claim 1 , pyridyl claim 1 , pyrimidinyl claim 1 , pyridazinyl claim 1 , or pyrazinyl claim 1 , each optionally fused to phenyl or a monocyclic heteroaryl claim 1 , and each optionally substituted with one or two substituents R.4. The compound of claim 1 , wherein Hetis thiazolyl claim 1 , thiadiazolyl claim 1 , pyridyl claim 1 , pyrimidinyl claim 1 , pyridazinyl claim 1 , benzoxazolyl claim 1 , quinazolinyl claim 1 , or triazolo-pyrimidinyl claim 1 , each optionally substituted with one or two substituents R.5. The compound of claim 1 , wherein each Ris independently selected from the group consisting of ...

METHOD FOR ENHANCING IMMUNOGENICITY OF EPITOPE PEPTIDE OF HPV ANTIGEN, VIRUS-LIKE PARTICLE, AND METHOD FOR PREPARING HPV VACCINE

A method for enhancing immunogenicity of an epitope peptide of an HPV antigen, the method including: assembling a gene of an HPV antigen into a gene of HBc, exogenously expressing a resulting assembled gene to acquire a fusion protein, allowing the fusion protein to automatically assemble to form a virus-like particle including the HPV antigen on a surface of the virus-like particle, to obtain HBc-HPV virus-like particle. A virus-like particle capable of expressing the antigen peptide of HPV acquired by the method. The virus-like particle includes a HBc-L2 fusion protein. A genome for encoding the HBc-L2 fusion protein is represented by SEQ ID NO. 3. A method for preparing an HPV vaccine includes using the virus-like particle. 1. A method for enhancing immunogenicity of an epitope peptide of an HPV antigen , the method comprising: assembling a gene of an HPV antigen into a gene of HBc , exogenously expressing a resulting assembled gene to acquire a fusion protein , allowing the fusion protein to automatically assemble to form a virus-like particle comprising the HPV antigen on a surface of the virus-like particle , to obtain HBc-HPV virus-like particle.2. The method of claim 1 , wherein the gene of the HPV antigen is a late transcribed region of HPV encoding a primary capsid protein L1 or a late transcribed region of HPV encoding a secondary capsid protein L2.3. The method of claim 1 , wherein the gene of the HPV antigen is a late transcribed region of HPV encoding a secondary capsid protein L2.4. The method of claim 1 , wherein the HPV antigen on the virus-like particle is one antigen peptide of L1 or one antigen peptide of L2 claim 1 , or multiple antigen peptides of L1 or L2 claim 1 , or a couplet of multiple antigen peptides of L1 or L2.6. The method of claim 1 , wherein the antigen peptide of HPV is totally exposed on the surface of the virus-like particle claim 1 , and the antigen peptide presented on the surface of the virus-like particle of HBc is multiple ...

Canoe pedal

The invention discloses a canoe pedal comprising a pedal plate arranged on a base. The canoe pedal is characterized in that the pedal plate comprises a pedal plate top and a pedal plate bottom, a fixing shaft is arranged on the pedal plate bottom and arranged on the base, the pedal plate can rotate along the fixing shaft, the pedal plate top is connected with a connecting shaft, the other end of the connecting shaft is provided with a steel wire rope winding seat, and the steel wire rope winding seat and a tail vane are connected through a steel wire rope. The canoe pedal of the structure integrates advantages of two kinds of pedals in the prior art, and the pedal plate bottom is a fixed pedal, can be treaded for power generation by a oarsman during canoeing, and serves as an acting point; the pedal plate top serves as a controller of the tail vane to control the direction of the tail vane; the oarsman can tread on different parts according to requirements simply and rapidly.

Remote autonomous VR exhibition watching robot system based on VR technology and motion control

According to the remote autonomous VR exhibition watching robot system based on the VR technology and motion control, a remote exhibition watcher remotely and autonomously controls movement of a robot to form a VR remote physical branch, travel expenses are saved, travel time is shortened, meanwhile, real-time real scene participation, immersion atmosphere and feeling, real-time field efficient communication and autonomous control over the live broadcast rhythm can be met, and the remote exhibition watching robot system is high in practicability and easy to popularize. And low-cost, multi-angle and high-degree-of-freedom VR live ...

Raw material feeding equipment for liquid crystal display screen frame production and feeding method thereof

The invention discloses raw material feeding equipment for liquid crystal display screen frame production and a feeding method thereof.The raw material feeding equipment is characterized in that limiting mechanisms are arranged on the two sides of the top of a conveying belt body, each limiting mechanism comprises a limiting plate and a connecting plate, the connecting plates are located on the back faces of the limiting plates, and rotating mechanisms are arranged between the connecting plates and the limiting plates; the rotating mechanism comprises a fixing plate, two fixing shafts and a rotating disc, the fixing plate is fixedly connected with the limiting plate, the opposite sides of the two fixing shafts are fixedly connected with the top end and the bottom end of the fixing plate respectively, one fixing shaft is fixedly connected with the rotating disc, the rotating disc is provided with a fixing mechanism, and the fixing mechanism comprises a bearing plate and a limiting rod. The ...

SUBSTITUTED PROLINES / PIPERIDINES AS OREXIN RECEPTOR ANTAGONISTS

The present invention is directed to compounds that modulate the bioactivity of an orexin receptor such as OXor OX, or both; to pharmaceutical compositions and combinations comprising a compound of the invention; to methods of treatment of malconditions in patients wherein modulation of an orexin receptor is medically indicated; and to methods of preparation of compounds of the invention. For example, orexin receptor-modulatory compounds of the present invention can be used in treatment of an eating disorder, obesity, alcoholism or an alcohol-related disorder, drug abuse or addiction including addiction to cocaine, opiates, amphetamines, or nicotine, a sleep disorder, a cognitive dysfunction in a psychiatric or neurologic disorder, depression, anxiety, panic disorder, schizophrenia, Alzheimer's disease, Parkinson's disease, Huntington's chorea, headache, migraine, pain, gastrointestinal diseases, epilepsy, inflammations, immune-related diseases, endocrine-related diseases, cancer, hypertension, behavior disorder, mood disorder, manic depression, dementia, sex disorder, psychosexual disorder, or renal disease. 118-. (canceled)20. The compound of claim 19 , wherein A is aryl claim 19 , and wherein A is unsubstituted or is mono- or independently multi-substituted with J or R′ claim 19 , or both.21. The compound of claim 19 , wherein A is selected from the group consisting of pyrazidinyl claim 19 , pyrimidinyl claim 19 , pyrazinyl claim 19 , thiazolyl claim 19 , pyrazolyl claim 19 , pyridyl claim 19 , and quinolyl claim 19 , and wherein A is unsubstituted or is mono- or independently multi-substituted with J or R′ claim 19 , or both.22. The compound of claim 19 , wherein A is unsubstituted.23. The compound of claim 19 , wherein A is mono-substituted with J or R′.24. The compound of claim 19 , wherein B is selected from the group consisting of phenyl claim 19 , pyridyl claim 19 , pyrazidinyl claim 19 , pyrimidinyl claim 19 , pyrazinyl claim 19 , pyrolyl claim 19 , ...

Use of Yibosu in preparing analgesics

The invention provides a novel application of Ebosin, in particular the application to the preparation of analgesic drugs. The Ebosin has main advantages of not only the obvious analgesic action, but also the stronger anti-inflammatory effect on big mouse acute inflammation, small mouse acute inflammation, small mouse proliferative inflammation, big mouse adjuvant-induced arthritis, type-2 collagen-induced arthritis, etc. when being used as an analgesic.

Hidden hatred speech detection and fine classification method and device based on combined comparative learning

The invention discloses an implicit hatred speech detection and fine classification method and device based on joint comparative learning, which can detect and finely classify hatred speech in social media, provide decision support for network space speech treatment, collect text data in online social media, construct and train an implicit hatred speech detection model, and improve the detection accuracy of the implicit hatred speech. The hidden hatred speech is obtained, knowledge enhancement is performed based on a common sense knowledge base ATOMIC, and the intention and subject reaction of a text sender and the object reaction of a reader are inferred; constructing and optimizing an implicit hatred speech classification model, respectively taking implicit hatred speech, intention, subject reaction and object reaction of the same category as positive samples in comparative learning to calculate comparative learning loss, performing weighted summation to obtain combined comparative learning ...

Processing method of ginger-processed dandelion roots

The invention relates to the technical field of traditional Chinese medicine processing, in particular to a processing method of ginger-processed dandelion roots. The invention provides a processing method of ginger-processed dandelion roots, the ginger-processed dandelion roots prepared by adopting the processing method and application of the ginger-processed dandelion roots. The method disclosed by the invention can be used for well eliminating the uncomfortable symptoms of the dandelion roots on people with deficiency-cold in spleen and stomach, increasing functional bioactive substances in the dandelion roots, well controlling the processing technological parameters of the ginger-processed dandelion roots and being suitable for industrial large-scale production.

Rolling bearing state identification method based on local tangent space weighted arrangement

The invention discloses a rolling bearing state identification method based on local tangent space weighted arrangement, and the method comprises the following steps: collecting original vibration sample signals of a rolling bearing, extracting time-frequency domain characteristic indexes, and forming a high-dimensional characteristic sample; constructing a rolling bearing state recognition model based on local tangent space weighted arrangement; training the rolling bearing state recognition model; and adopting the trained rolling bearing state recognition model to obtain a rolling bearing state recognition result. According to the method, the geodesic distance capable of reflecting a high-dimensional data manifold structure is adopted as a weight coefficient, local low-dimensional coordinates are rearranged according to weights, so that the arrangement error is reduced, after the bearing high-dimensional feature sample is subjected to WBLTSA manifold learning dimension reduction, the ...

Method for transferring alarm of client access link in transmission system

The invention relates to a method for transferring the alarm of a client access link in a transmission system, which is characterized in that data equipment A is connected with transmission equipment A through active/standby links A_W and A_P, and data equipment B is connected with transmission equipment B through active/standby links B_W and B_P; when the active link A_W fails, the service of A site is switched to the standby link A_P from the active link A_W, and alarm information is sent; the transmission equipment A sends a client management frame CSF of GFP at regular time, and the client management frame is transferred to the transmission equipment B through an SDH channel N_W; the transmission equipment B turns off the active link B_W so as to enable the service to be switched to the standby link B_P from the active link B_W of the data equipment B, thereby ensuring that A site and B site work on the standby link. The method transfers the alarm of an Ethernet access link of thedata ...

Multichannel high-definition video overlapping method based on FPGA (field programmable gata array)

The invention relates to the video overlapping technology, in particular to a multichannel high-definition video overlapping method based on a FPGA (field programmable gata array). The multichannel high-definition video overlapping method based on the FPGA includes that a video source is converted to a digital signal through an A/D (analog to digital) chip and then enters into the FPGA, the FPGA collects effective pixels, clock domain conversion processing is performed on each channel of the video through an FIFO, all the video is unified to an inner clock of the FPGA, a video zooming module is built inside the FPGA and caches a frame of data in each channel of the video which is zoomed into a DDR3, a traveling field synchronization module of a VESA (video electronics standards association) standard is built inside the FPGA, and simultaneously data of each channel of the video is red from the DDR3, frame synchronization is performed on the data, an alhpa mixture overlapping module is built ...

Method for predicting river basin climatic change and analyzing tendency

The invention discloses a method for predicting river basin climatic change and analyzing tendency, comprising the following three steps: 1. determining the average air temperature, the rainfall and the runoff of a river basin by an 'equipartition principle'; 2. substituting the average air temperature, the rainfall and the runoff data of the river basin in 30 years or a longer time period into the Matlab of the autocorrelation function of a chaotic time series, and solving the delay time tau; according to the delay time tau, building the input and output vectors of the training sample of an Elman artificial neural network; designing an Elman network by a newrb function; finally, predicting the average air temperature, the rainfall and the runoff of the river basin by a sim function; and 3. calculating the variation tendency and the mutant site of the average air temperature, the rainfall and the runoff of the river basin with an M-K non-parameter tendency test method. With the method, ...

Yibosu capsule and its preparation method

The invention provides an Ebosin capsule which is prepared by taking Ebosin as a raw material medicine and taking hydroxypropyl methylcellulose as an auxiliary material. The invention also provides a preparation method of the Ebosin capsule. The Ebosin capsule has remarkable inhibitory effects on acute inflammation, subacute inflammation, chronic inflammation, and particularly to rheumatoid arthritis; the drug action is obvious, the toxicity is very low, the medication is safe, and the price is low; the medicament form of the Ebosin capsule realizes the convenient carrying and easy administration.

Substituted pyrimidinyl-amines as protein kinase inhibitors

The present invention provides novel substituted pyrimidinyl-amines that are useful as inhibitors of protein kinases, especially c-Jun N-terminal kinases (JNK) and pharmaceutical compositions thereof and methods of using the same for treating conditions responsive to the inhibition of the JNK pathway.

Circulating miRNA Biomaker Signatures

Methods for diagnosis and surveillance of complex multi-factorial disorders such as cancer by screening of easily accessible biomarkers are disclosed. Highly stable cell free Circulating Nucleic Acids (CNA) present as both RNA and DNA species have been discovered in the blood and plasma of humans. Correlations between tumor-associated genomic/epigenetic/transcriptional changes and alterations in CNA levels are strong predictors of the utility of this biomarker class as clinical indicators. Methods for using microRNAs (miRNAs) representing a class of naturally occurring small non-coding RNAs of 19-25 nt as markers that can associate their specific expression profiles with cancer development are disclosed. Methods for isolating plasma fractions for the study of miRNA biomarkers and for measurement of circulating miRNA levels are disclosed. 1. A method for obtaining a sample that is enriched for circulating miRNAs comprising: (a) spinning a sample of blood to separate it into a cloudy supernatant fraction , a white blood cell fraction and a red blood cell fraction; (b) spinning the cloudy supernatant fraction to separate it into a first supernatant and a first pellet; (c) optionally spinning the first supernatant to separate it into a second supernatant and a second pellet; (d) extracting total RNA from either the first supernatant , if step (c) has not been performed , or the second supernatant if step (c) has been performed , wherein the resulting total RNA is enriched in circulating miRNAs as compared to the starting blood sample.2. The method of wherein the spin of step (a) is at about 1700 g for 10 min.3. The method of wherein the spin of step (b) is at about 2000 g for 10 min.4. The method of wherein the spin of step (c) is at about 12000 g for 10 min.5. The method of further comprising hybridizing the total RNA to an array comprising probes complementary to miRNA.6. A method for determining if a sample is derived from a female claim 1 , comprising analyzing the ...

Method for preventing sludge from sticking to device when sticky sludge is improved, solidified and processed

The invention relates to a method for preventing sludge from sticking to a device when sticky sludge is improved, solidified and processed. The method is characterized by comprising the following steps that (1), before the sludge is fed to a sludge conveyor chain board, the chain board is evenly coated with powdery solidification materials through an anti-sticking powder coating device; (2), when the conveyor chain board conveys the sludge to the tail end of a sludge discharge device, the powdery solidification materials are sprayed to the surface and surroundings of the sludge and a belt conveyor used for conveying the sludge through another anti-sticking powder coating device. The method is used for preventing the sludge from sticking to the conveying device when characteristic sludge which is high in moisture content, clay content, organic matter and stickiness is improved, solidified and processed, the working efficiency of a sludge processing device is improved, the probability of ...

Multi-microecological preparation for improving aquaculture water environment and preparation method thereof

The invention discloses a multi-microecological preparation for improving the aquatic water environment and a preparation method thereof, and belongs to the field of microecological preparations, the microecological preparation for improving the water quality can maintain the ecological balance of a water body through the proportion of all the components, and the microecological preparation for improving the water quality has the function of catalytically degrading one or more organic pollutants in the water body environment, and has a good application prospect. The compound micro-ecological preparation can effectively improve the water quality, after the compound micro-ecological preparation is added into a culture water body, part of the compound micro-ecological preparation can enter aquatic animal bodies along with water flow, then the number of beneficial microbial communities in intestinal tracts is supplemented, the beneficial microbial communities occupy absolute advantages, breeding ...

Method for processing light direction information of communication channels of packet transport equipment

The invention discloses a method for processing light direction information of communication channels of packet transport equipment and relates to the field of packet transport network equipment. The method comprises the following steps of: identifying the light direction information in a management communication channel (MCC) and a signaling communication channel (SCC) of the packet transport network equipment, wherein the light direction information comprises slot position information and light port information; placing the slot position information at the high order of the light direction information, and placing the light port information at the low order of the light direction information; and identifying and processing the high order of the light direction information, carried by a management frame received by a management card, by the management card, and identifying and processing the low order of the light direction information, carried by the management card received by a business ...

Multicast non-blocking cross architecture

The invention relates to a multicast non-blocking cross architecture, and relates to a cross architecture of T-MPLS equipment. The multicast non-blocking cross architecture is characterized in that the cross architecture comprises three parallelly positioned XS cross chips; the input interface and output interface of each XS cross chip are respectively an X_IN interface and an X_OUT interface; the X_IN interface of each XS cross chip is in balanced connection with two different TG input groups; each TG input group occupies NG/2 of the bandwidth of the corresponding XS cross chip, and NG is the bandwidth of an XS cross chip; and the X_OUT interface of each XS cross chip is in balanced connection with two different TG output groups. The multicast non-blocking cross architecture adopts a method of concurrent receiving and balanced cross to meet the requirements on a large-capacity cross matrix; and the cross architecture has simple cross routing algorithm and can easily realize non-blocking ...

Yibosu and its quality control method

The invention provides Ebosin containing polysaccharide, wherein, the polysaccharide contains the monosaccharide by weight percentage as follows: 3.0 to 4.0 percent of rhamnose, 4.0 to 6.0 percent xylose, 0.0 to 2.0 percent of glucose, 3.0 to 5.0 percent of seminose, 16 to 12 percent of gum sugar, 3.0 to 5.0 percent of fucose, 12 to 19 percent of galactose, 3.0 to 5.0 percent of galacturonic acid, etc.; the species quantity of the monosaccharide is eight. The molecular exclusion chromatography is adopted to measure the peak molecular weight of the Ebosin, which is 40.0*10<4>-90.0*10<4>. The invention also provides a method for controlling the quality of the Ebosin. The quality controlling method has high sensitivity, strong specialization, simple and convenient operation and easy detection, and is an ideal quality controlling method for the microbial polysaccharide.

Method for promoting growth and development by irrigating tomatoes with marsh gas fermentation liquor

The invention discloses a method for promoting growth and development of tomatoes by irrigating the tomatoes with marsh gas fermentation liquor. The method for promoting the growth and the development of the tomatoes by irrigating the tomatoes with the marsh gas fermentation liquor includes following steps: (a1), mixing materials according to the proportion: 5-15kg of vegetable residual body waste, 30-50kg of an marsh gas assistant agent and 100-140L of water, and obtaining the marsh gas fermentation liquor after generating gas through anaerobic fermentation; (a2) using water to dilute the marsh gas fermentation liquor obtained in the step (a1), wherein use quantity of the water is less than 60% of the total volume of the marsh gas fermentation liquor after being diluted; (a3) using the marsh gas fermentation liquor obtained in the step (a1) or the marsh gas fermentation liquor after being diluted in the step (a2) to irrigate target tomato seedlings, irrigating the target tomato seedlings ...

Small-capacity PTN (Package Transport Network) equipment based on single core exchange chip and business realizing method thereof

The invention discloses small-capacity PTN (Package Transport Network) equipment based on a single core exchange chip and a business realizing method thereof. The method comprises the following steps of: dividing a data transmitting area of a core exchange chip into a transmitting area A and a transmitting area B, wherein the transmitting area A is used for realizing an LSP (Label Switch Path) protecting function, the transmitting area B is used for realizing a VPN (Virtual Private Network) business function, and even maximum speed interfaces of the core exchange chip are connected mutually in pair to form a loop link; accessing a local business from an uplink or downlink branch interface disk; carrying out VPN packaging in the transmitting area B; then entering the transmitting area A through the loop link for carrying out LSP protection processing; finally sending out from a downlink or uplink line interface disk; accessing a forwarding business from the uplink or downlink line interface ...

Method for transferring alarm of client access link in transmission system

The invention relates to a method for transferring the alarm of a client access link in a transmission system, which is characterized in that data equipment A is connected with transmission equipmentA through active/standby links A_W and A_P, and data equipment B is connected with transmission equipment B through active/standby links B_W and B_P; when the active link A_W fails, the service of A site is switched to the standby link A_P from the active link A_W, and alarm information is sent; the transmission equipment A sends a client management frame CSF of GFP at regular time, and the clientmanagement frame is transferred to the transmission equipment B through an SDH channel N_W; the transmission equipment B turns off the active link B_W so as to enable the service to be switched to the standby link B_P from the active link B_W of the data equipment B, thereby ensuring that A site and B site work on the standby link. The method transfers the alarm of an Ethernet access link of thedata ...

Method for preventing and controlling aquaculture environment pollution

The invention discloses a method for preventing and controlling aquaculture environment pollution, and belongs to the field of mixers.The method for preventing and controlling aquaculture environment pollution comprises the following steps that S1, strain mutagenesis screening is conducted, specifically, strains with the high reproductive capacity and the high nitrite degradation capacity are further screened out, and the strains are identified; s2, strain compatibility: forming a set of complete method and scheme for preventing and controlling blue-green algae, and developing corresponding products; s3, biological substrate modification is studied, wherein the effect and influence of compatibility and proportion of different strains on the substrate are studied; and S4, researching and exploring the use of the microecological preparation in different aquaculture water bodies, a proper adding proportion and a proper adding mode, and establishing a model, so that the balance effect of the ...

Transistor Bias Adjustment for Optimization of Third Order Intercept Point in a Cascode Amplifier

Methods and devices for amplifying an input RF signal according to at least two gain-states is described. According to one aspect, a multi gain amplifier circuit including a low noise amplifier having a stack of transistors is used for amplification of the input RF signal. When switching from a low gain-state to a high gain-state, the drain-to-source voltage of the output transistor of the stack is increased to affect region of operation of the output transistor, and thereby reduce non-linearity at the output of the amplifier. When switching from the high gain-state to the low gain-state, the drain-to-source voltage of the input transistor of the stack is increased to affect region of operation of the input transistor, and thereby reduce non-linearity at the output of the amplifier. 120.-. (Canceled)21. A multi-gain-state amplifier circuit for operation according to at least a low gain-state and a high gain-state , the multi-gain-state amplifier circuit comprising: 'a stack of a plurality of series connected transistors comprising an input transistor and one or more cascode transistors comprising an output transistor, the stack coupled between a substantially fixed supply voltage and a reference ground; and', 'i) a low noise amplifier (LNA) comprisingii) a gain decoder and bias control circuit that is configured to selectively generate biasing voltages to gates of the one or more cascode transistors for operation according to the low gain-state and the high gain-state,wherein during operation in the high gain-state, the biasing voltages are configured to provide a drain-to-source voltage of the output transistor that is higher than a drain-to-source voltage of the output transistor during operation in the low gain-state.22. The multi-gain-state amplifier circuit according to claim 21 , wherein during operation in the low gain-state claim 21 , the biasing voltages are configured to provide a drain-to-source voltage of the input transistor that is higher than a drain- ...

Handheld cable detector

The utility model provides a handheld cable detector relates to cable detection area, including anterior, the three part of dismantling the connection in middle part and rear portion, front portion and middle part and middle part and rear portion are all connected through jack and electric plug cooperation, it is anterior including the handle handle, be equipped with power change -over switch, detection switch, pilot lamp, jack and the interface that charges on the handle, the middle part is including a casing, be equipped with electric plug, jack and two current display of being connected with the cooperation of anterior jack on the casing, inside charged battery and the battery compartment of being equipped with of casing, the rear portion includes a casing, the casing is inside including the circuit board, the casing left part is equipped with the electric plug of being connected with the cooperation of middle part jack, the casing right part is equipped with the terminal. Terminal, ...

Annular rotatable impact test simulation device under high temperature condition

The invention provides an annular rotatable high-temperature impact test simulation device which comprises a high-temperature furnace and is characterized in that the annular rotatable high-temperature impact test simulation device is further provided with an annular clamp table, the annular clamp table comprises a pair of annular sliding rails, a plurality of high-temperature clamps and a plurality of supporting modules, and each supporting module comprises a clamp table frame, a supporting plate and two annular sliding rings. A plurality of test pieces can be assembled at a time, when the device is assembled for testing, the test pieces can be transferred into or out of a high-temperature furnace in turn by rotating the annular sliding rail, in the process that one test piece is subjected to an impact test, the test piece subjected to the test can be cooled outside the high-temperature furnace, the test piece replacement flow is simple, and the test efficiency is high. The test efficiency ...

Low-temperature adsorption testing device and testing method thereof

The invention discloses a low-temperature adsorption testing device and a testing method thereof, and belongs to the technical field of low-temperature adsorption, and the testing device comprises a control system, an adsorption system and an analysis system which are mutually connected through a process pipeline and a valve assembly. The testing device is simple and flexible to operate, comprehensive and accurate in testing, and capable of completing the influence of different temperatures, pressures, flow rates and height-diameter ratios on the adsorption performance of the adsorbent to form a low-temperature adsorption database. The test method is realized through the test device, firstly analyzes the gas components of the raw material gas, then analyzes the balance gas components of the outlet of the gas-liquid separator, and finally analyzes the gas components of the outlet of the adsorber, has the advantages of wide test range, abundant evaluation means and accurate test data, and ...

Water resource bearing capacity evaluation method

The invention discloses a water resource bearing capacity evaluation method. The method comprises the following six steps of: firstly, determining an evaluation index weight by utilizing an information entropy principle; secondly, constructing a set pair model of an evaluation region and water resource bearing capacity evolution, introducing a concept of contact numbers, and contacting the identical discrepancy contrary of the set pair model; thirdly, based on an evaluation index system, calculating the contact numbers of each layer respectively from the bottom to the top, obtaining the contact number of the last layer in turn by combining a weight vector, and analogizing one by one by obtain the contact numbers of the overall system; fourthly, determining the values of the contact numbers of the systems at each level and a principal value of an n-component contact number by utilizing an equipartition principle; fifthly, equally dividing an interval [-1,1] into n levels by utilizing the ...

Recognition and positioning method, device and equipment for lost children and medium

The embodiment of the invention discloses an identification and positioning method for lost children, the method is applied to an intelligent inspection robot, and the method comprises the following steps: acquiring image information and video information acquired on the intelligent inspection robot based on a preset infrared camera module; based on the image information and the video information, acquiring face image information in a current visible range of the infrared camera module; inputting the face image information into a pre-trained cross-age neural network model to output a judgment result; if it is determined that the target person exists in the current visual range based on the judgment result, target image information of the target person is extracted; and acquiring current position information of the target person based on the target image information, and acquiring a motion track of the target person through the video information, so as to determine a tracking route of the ...

Circulating miRNA biomaker signatures

Methods for diagnosis and surveillance of complex multi-factorial disorders such as cancer by screening of easily accessible biomarkers are disclosed. Highly stable cell free Circulating Nucleic Acids (CNA) present as both RNA and DNA species have been discovered in the blood and plasma of humans. Correlations between tumor-associated genomic/epigenetic/transcriptional changes and alterations in CNA levels are strong predictors of the utility of this biomarker class as clinical indicators. Methods for using microRNAs (miRNAs) representing a class of naturally occurring small non-coding RNAs of 19-25 nt as markers that can associate their specific expression profiles with cancer development are disclosed. Methods for isolating plasma fractions for the study of miRNA biomarkers and for measurement of circulating miRNA levels are disclosed.

Hyposialylation disorders

Methods are disclosed for diagnosing a hyposialylation disorder. Methods are also disclosed for determining the effectiveness of a therapeutic agent for treatment of a hyposialylation disorder in a subject. These methods include measuring an amount of monosialylated Thomsen-Friedenreich (ST) antigen and measuring an amount of non-sialylated Thomsen-Friedenreich antigen (T) in a biological sample, such as a serum or plasma sample from the subject and determining the ratio of T to ST. A ratio of T to monosialylated ST of about 0.06 or higher diagnoses the hyposialylation disorder or indicates that the therapeutic agent is not effective for the treatment of the hyposialylation disorder. In other embodiments, a ratio of T to ST less than about 0.06 indicates that the therapeutic agent is effective for the treatment of the hyposialylation disorder, or the subject does not have the hyposialylation disorder. In additional embodiments, these methods can be used to determine the lowest effective dosage of the therapeutic agent of use to treat the subject.

Intelligent oleamen coating device that optical fiber cable used

The utility model discloses an intelligent oleamen coating device that optical fiber cable used, including longitudinal covering rack, support frame, oil storage tank, shower nozzle mechanism, microcontroller, electronic scale and supporting mechanism, the base station fixed surface of support frame has two x to install on carrying the thing board to line rail, shower nozzle mechanism, and this shower nozzle mechanism includes that oil storage cavity, oil storage cavity one end are connected to the first port of tee bend head, the second port of tee bend head, third port respectively with advance oil pipe, the manometer is connected, the oil storage cavity other end is connected to the fuel sprayer, a bracing piece with the supporting mechanism is located the fuel sprayer both sides respectively and is located its below to formation supplies the passageway of strap transmiting between fuel sprayer and bracing piece and supporting mechanism, and one mends oil pipe is connected to oil storage ...

Method for evaluating fragility of water resource under climatic change

The invention provides a method for evaluating the fragility of a water resource under climatic change. The method comprises the following steps of: 1, determining an evaluation index weight by a characteristic vector method; 2, constructing an evaluation region and a set pair model for evaluating the fragility of the water resource and introducing a concept of a correlate so as to correlate the set pair model and opposition; 3, calculating the correlates of each layer from bottom to top respectively according to an evaluation index system so as to sequentially obtain the correlate of the former layer in combination with a weight vector, and gradually analogizing to obtain the correlate of the main system; 4, determining the value of the correlate of each level of system and a main value of n-element correlate of a main index by using an averaging principle; 5, averaging a region [-1 and 1] into n levels according to the concept of the correlate by using the averaging principle so as to ...

Tail gas collecting and exhausting device for automobile assembly lines

The invention discloses a tail gas collecting and exhausting device for automobile assembly lines, which comprises automobile conveying plate chains arranged on the indoor ground, wherein a section of tail gas collecting and air exhausting channel with an upper opening is arranged between the automobile conveying plate chains; a grating plate is covered on the upper opening of the tail gas collecting and air exhausting channel; exhaust holes are formed on the wall and/or the bottom of the tail gas collecting and air exhausting channel; the exhaust holes are connected and communicated with an inner exhaust pipe; an exhaust blower is connected on the inner exhaust pipe; the gas outlet of the exhaust blower is connected with an outer exhaust pipe; the outer exhaust pipe is arranged outside; and an automobile tail gas collecting chamber cover with two open ends is arranged on the ground of the tail gas collecting and air exhausting channel. Because the chamber type collecting chamber cover ...

Substituted prolines / piperidines as orexin receptor antagonists

The present invention is directed to compounds that modulate the bioactivity of an orexin receptor such as OX1 or OX2, or both; to pharmaceutical compositions and combinations comprising a compound of the invention; to methods of treatment of malconditions in patients wherein modulation of an orexin receptor is medically indicated; and to methods of preparation of compounds of the invention. For example, orexin receptor-modulatory compounds of the present invention can be used in treatment of an eating disorder, obesity, alcoholism or an alcohol-related disorder, drug abuse or addiction including addiction to cocaine, opiates, amphetamines, or nicotine, a sleep disorder, a cognitive dysfunction in a psychiatric or neurologic disorder, depression, anxiety, post-traumatic stress disorder, seasonal affective disorder, an eating disorder, panic disorder, schizophrenia, Alzheimer's disease, Parkinson's disease, Huntington's chorea, headache, migraine, pain, gastrointestinal diseases, epilepsy ...

Large nursery stock transplanting lifting auxiliary device and control method

The invention relates to the related technical field of tree transplanting, and discloses a large nursery stock transplanting lifting auxiliary device and a control method.The large nursery stock transplanting lifting auxiliary device comprises a soil ball hanging belt, a trunk hanging belt and a hoop assembly, the hoop assembly comprises a connecting belt and a hoop, the connecting belt is connected with the hoop, the soil ball hanging belt and the trunk hanging belt both penetrate through the hoop, and the connecting belt is connected with the hoop. A rope penetrating ring is installed on the hoop ring and used for penetrating through a rope to adjust the position of the hoop ring through pulling, a cutting assembly is arranged on the soil ball hanging belt and comprises a shell, a cutting body and an operation part, and the operation part is connected with the cutting body. The cutting of the soil ball binding material is realized by utilizing the hoisting equipment and the gravity of ...

Feed feeding device for livestock

The utility model relates to the technical field of feed, in particular to a feed feeding device for livestock, which comprises a base and further comprises a box body convenient-to-disassemble mechanism, a feed mixing mechanism and a feeding mechanism. Supporting plates are symmetrically and fixedly connected to the bottom of the base, and rolling wheels are arranged on the supporting plates. The box body convenient-to-disassemble mechanism is arranged on the top of the base and comprises a first fixing box and a second fixing box, the first fixing box is not provided with a top plate, the second fixing box is not provided with a bottom plate, and fixing blocks are fixedly connected to the outer side of the top end of the first fixing box and the outer side of the bottom end of the second fixing box. The vertical rod and the mixing rod are driven by the motor to rotate, feed mixing is achieved, sundries are filtered through the filter plate, the annular plate is driven to move up and down ...

Preparation method of water-based adhesive for labels

The invention discloses a preparation method of a water-based adhesive for labels, and belongs to the technical field of adhesives, and the preparation method comprises the following steps: step S1, stirring and mixing oligomer polyol, isophorone diisocyanate and 2, 2 '-dimethylolbutyric acid, heating, adding dibutyltin dilaurate for reaction, cooling, adding 1, 4-butanediol for reaction, and cooling to obtain a prepolymer; then adding dimethyl glyoxime, and reacting for 4-6 hours at the temperature of 80-85 DEG C to obtain an end-capped prepolymer; s2, cooling the terminated prepolymer to 45-50 DEG C, adding acetone to adjust the viscosity, adding triethylamine to neutralize when the temperature is reduced to 30 DEG C, adding deionized water to emulsify, adding ethylenediamine to carry out chain extension reaction, heating to 60 DEG C, curing for 4 hours, and carrying out reduced pressure distillation to remove the acetone, so as to obtain the water-based adhesive for the label; the prepared ...

Flocculating agent adding device for mine filling tailing groove

The invention relates to the technical field of mine filling, in particular to a mine filling tailing tank flocculant adding device which comprises a liquid storage tank, a tank cover is mounted at the upper end of the liquid storage tank, a feeding pipe is connected to the upper end of the tank cover, and a water pump is mounted at the upper end of the tank cover. According to the device, the added flocculation liquid can be conveniently subjected to two-layer filtering, the filtering mechanism can be conveniently cleaned in time during filtering, blockage and influence on continuous adding of the flocculation liquid are avoided, the adding range of the flocculation liquid can be conveniently and effectively adjusted, tailings slurry particles can be conveniently precipitated after large-area contact reaction with the flocculation liquid, and the flocculation liquid can be effectively filtered. The flocculating liquid adding efficiency is effectively improved.

Oleamen deposited paint finishing for optical fiber cable

The utility model discloses an oleamen deposited paint finishing for optical fiber cable, including longitudinal covering rack, support frame, oil storage tank, shower nozzle mechanism and supporting mechanism, the base station fixed surface of support frame has two x to the line rail, and this x is fixed in the recess of x to the slider that carries thing board lower surface to the embedding of line rail in, shower nozzle mechanism installs on carrying the thing board, and this shower nozzle mechanism includes that oil storage cavity, oil storage cavity one end are connected to the first port of tee bend head, the second port of tee bend head, third port respectively with advance oil pipe, the manometer is connected, the oil storage cavity other end is connected to the fuel sprayer, a bracing piece with the supporting mechanism is located the fuel sprayer both sides respectively and is located its below to form the passageway that supplies the strap transmiting between fuel sprayer and ...

Zirconium-based metal organic framework/reduced graphene oxide composite material and preparation method and application of working electrode

The invention relates to a preparation method and application of a zirconium-based metal organic framework/reduced graphene oxide composite material and a working electrode. The invention relates to a preparation method of a zirconium-based metal organic framework/reduced graphene oxide composite material. The preparation method comprises the following steps: (1) preparing reduced graphene oxide by adopting an acetic acid-hydriodic acid method; and (2) preparing the zirconium-based metal organic framework/reduced graphene oxide composite material by taking the reduced graphene oxide, zirconium tetrachloride and aminoterephthalic acid as raw materials and adopting a one-pot solvothermal method. The invention relates to a preparation method and application of a zirconium-based metal organic framework/reduced graphene oxide composite material and a working electrode. The preparation method comprises the following steps: firstly, preparing reduced graphene oxide (rGO) through an acetic acid-hydriodic ...

Carboxylated triheptyl citrate calcium salt lubricating oil detergent and preparation method thereof

The invention discloses a carboxylated triheptyl citrate calcium salt lubricating oil detergent and a preparation method thereof. The detergent disclosed by the invention contains the following raw materials: 5-25mol% of carboxylated triheptyl citrate, 15-40mol% of calcium oxide, 2-10 mol% of a dispersing agent, 10-40mol% of a solvent, 0.5-5mol% of an accelerant, 1-5mol% of a cosolvent and 10-40mol% of carbon dioxide, wherein the carboxylated triheptyl citrate has a molecular structure shown as a formula I. The detergent provided by the invention has excellent high temperature resistance.

Method for preparing ebosin

The invention provides a method for making Ebosin. The method comprises two steps of strain cultivation and polysaccharide separation and differentiation. Moreover, the method increases the output of microorganism polysaccharide, and the obtained medicine has the characteristics of high content, high output, simple and controllable process and easily realized large-scale industrial production, etc.

Inflatable adjustable canoe seat

The invention discloses an inflatable adjustable canoe seat which comprises a canoe seat body. The canoe seat body comprises a base, a left side back support and a right side back support. The inflatable adjustable canoe seat is characterized in that the base is provided with a first air bag, the left side back support and the right side back support are provided with a second air bag and a third air bag respectively, the first air bag is connected with a first inflation ball, the second air bag is connected with a second inflation ball, and the third air bag is connected with a third inflation ball. The inflatable adjustable canoe seat can be adjusted anytime anywhere so as to adapt to people having different weights, heights and use hobbies, and the most comfortable state is achieved rapidly. Furthermore, the first air bag comprises an outer layer wrapping layer formed by a breathable mesh-shaped fabric and an internal filling layer formed by EVA foam. Even if the canoe seat is soaked ...

Liquid-phase fluid uniform distribution device of coiled tube type heat exchanger

The invention belongs to the technical field of fluid uniform distribution, and particularly relates to a liquid-phase fluid uniform distribution device of a coiled tube type heat exchanger. According to the technical scheme, the liquid-phase fluid uniform distribution device of the wound tube type heat exchanger comprises a center cylinder, the side wall of the center cylinder is fixedly connected with the liquid-phase fluid uniform distribution device in a sleeved mode, an upper-layer liquid distribution disc and a lower-layer liquid distribution disc are arranged in the liquid-phase fluid uniform distribution device, and the upper-layer liquid distribution disc and the lower-layer liquid distribution disc are each provided with a plurality of open holes. The hole diameter and the hole distance of the holes in the upper-layer liquid distribution plate are greater than those of the holes in the lower-layer liquid distribution plate; a lateral opening is formed in the central cylinder and ...

Traffic radar speed measurement method and device, radar and readable storage medium

The invention relates to the technical field of radar speed measurement, and provides a traffic radar speed measurement method and device, a radar and a readable storage medium, and the traffic radar speed measurement method comprises the following steps: obtaining an echo signal of a target vehicle, and carrying out the frequency mixing orthogonal processing of the obtained echo signal and a transmission signal, two paths of characteristic signals of the target vehicle are obtained; sampling the obtained characteristic signal according to a set number of sampling points, and performing analog-to-digital conversion on the sampled signal; performing interference removal and operation transformation processing on the obtained digital signal to extract a target signal frequency spectrum of the target vehicle; correcting the obtained frequency spectrum of the target signal through a frequency spectrum correction algorithm so as to filter out sinusoidal signals in the frequency spectrum of the ...

SUBSTITUTED PYRIMIDINYL-AMINES AS PROTEIN KINASE INHIBITORS

Intelligent security and protection system for incineration power plant

The invention provides an intelligent security and protection system for an incineration power plant. The intelligent security and protection system comprises a personnel positioning module, a video monitoring module, a system communication network module and a system software management module, the personnel positioning module is used for registering and distributing wireless radio frequency positioning tags, fixing the wireless radio frequency positioning tags on personal safety helmets and wrist straps or making the wireless radio frequency positioning tags into work cards, exchanging data with a base station through wireless radio frequency communication, and establishing personnel coordinates in combination with a building model; the video monitoring module integrates existing camera equipment into the video monitoring module and can display video pictures of all cameras in real time; the system communication network module connects the base stations and then accesses the Ethernet ...

T-MPLS device model and layering encapsulating method

The invention provides a T-MPLS device model and a layering encapsulating method, wherein, the device model comprises a business interface unit which is used for accessing and encapsulating varied businesses in different TMCs and sending the businesses to a cross unit in a convergent manner; the cross unit is used for encapsulating various different TMC businesses from the business interface unitinto different TMPs and then forwarding a business package with two layers of labels to different line units, and meanwhile is in charge of protection switching of varied businesses, generation and finalization of an OAM packet on a TMC layer and OAM on a TMP layer; and the line units are used for forwarding a data packet with the two layers of labels sent from the cross unit to a T-MPLS network,and meanwhile are in charge of generation and finalization of the OAM on a TMS layer. The invention has a clear layered architecture, can help easily realize varied layering functions and varied protection ...

Hydrodynamic performance testing method of water surface aircraft

A hydrodynamic performance testing method of a water surface aircraft is characterized in that the following testing steps are included as follows (a), test equipment is installed; (b), the testing method is as follows: two forces FX and FZ are respectively applied on a water surface aircraft test sample (2), the outputs of a two component force balance (6) and a single component force balance (13) are measured to make sure FX1 on the two component force balance (6) is the FX, the sum of FZ1 on the two component force balance (6) and FZ2 on the single component force balance (13) is FZ. A hydrodynamic test trailer with high speed is started and is also used for collecting data. According to collected test results, the data need to be analyzed, and the hydrodynamic performance of the water surface aircraft in the process of sliding on the water surface is acquired. The hydrodynamic performance testing method of the water surface aircraft has the advantages that test influence between force ...

Method for distributing T-MPLS looped network label

The invention discloses a distribution method for a T-MPLS ring network label and relates to ring network label distribution. The method comprises the following steps: 1. global TUNNEL labels are distributed for nodes; 2. local PW labels are distributed for services; and 3. the TUNNEL labels encapsulated in the up direction are TUNNEL labels of old nodes, and the encapsulated PW labels are PW labels which are distributed by the old nodes for the service; terminated TUNNEL labels in the down direction are TUNNEL labels of the node; and the terminated PW labels are PW labels which are distributed by the node for the service. The method carries out TUNNEL configuration by taking the destination node as guide and the total number of the TUNNEL labels is equal to the total number of all the nodes, therefore, the total number of the TUNNEL labels is not increased along with the increasing of services, and the labels can be repeatedly used by all the nodes without causing error connection, thus ...

Method for manufacturing grass linen double-faced picture

The invention discloses a method for manufacturing a grass linen double-faced picture, comprising several steps of outline printing, ink drafting on the front face and the back face of grass linen, ink complementing on the front face and the back face of the grass linen, coloring on the front face and the back face, color complementing on the front face and the back face, ink complementing on thefront face and the back face and the like. In the processes of ink drafting and coloring on the grass linen picture, different felt pads with deep and shallow chroma are alternately adopted and used as the basic reference color of the double-faced grass linen picture, the problem of difficult uniformity of the double-faced effect of the grass linen double-faced picture is technically solved, the artistic effects of uniform and delicate figure coloring and clear hierarchy of the grass linen double-faced picture are realized, a novel picture species is created, the history that Chinese picturesonly ...

T-MPLS device model and layering encapsulating method

The invention provides a T-MPLS device model and a layering encapsulating method, wherein, the device model comprises a business interface unit which is used for accessing and encapsulating varied businesses in different TMCs and sending the businesses to a cross unit in a convergent manner; the cross unit is used for encapsulating various different TMC businesses from the business interface unitinto different TMPs and then forwarding a business package with two layers of labels to different line units, and meanwhile is in charge of protection switching of varied businesses, generation and finalization of an OAM packet on a TMC layer and OAM on a TMP layer; and the line units are used for forwarding a data packet with the two layers of labels sent from the cross unit to a T-MPLS network,and meanwhile are in charge of generation and finalization of the OAM on a TMS layer. The invention has a clear layered architecture, can help easily realize varied layering functions and varied protection ...

Mixed gas for cutting

The present invention relates to a cutting mixed gas. It is made up by adding 99.5% methyl alcohol to methane liquefied gas for cutting metal. It is low in cost, simple in technological process, goodin cutting efficiency, and has no pollution.

Microwave integrated circuit (MIC) coprocessor-based whole-network shortest path planning parallelization method

The invention discloses a microwave integrated circuit (MIC) coprocessor-based whole-network shortest path planning parallelization method. The whole network comprises N nodes. The method comprises the following steps: (1) defining each node into a unit which cannot be divided again relative to other nodes of the whole network, wherein the whole network formed by N nodes has N unit tasks; (2) taking K unit tasks as a task packet, creating P=N/K task packets, creating P=[N/K]+1 task packets as to the condition that N cannot be exactly divided by N, wherein [N/K] represents taking an integer part, dividing into K cycles to orderly execute K unit tasks after each thread takes one task packet; (3) carrying out task scheduling (4) by the created P task packets between L threads, outputting the path planning result and downloading the whole-network path planning data to a host computer after the whole-network nodes are processed for online service program enquiry of path planning.

Soil pollution ecological effect quantitative evaluation method based on field ecological data

The invention provides a soil pollution ecological effect quantitative evaluation method based on field ecological data, and belongs to the technical field of regional soil pollution ecological effect quantitative evaluation. According to the method, dominant pollutants and main environmental influence factors are identified through sorting analysis; screening an evaluation end point by utilizing correlation analysis; constructing an exposure-effect relation curve based on a Bayesian kernel machine regression model, and calculating the pollutant effect concentration of each evaluation end point; and finally, deducing the pollutant hazard concentration according to the probability distribution curve model, and quantitatively evaluating the regional soil pollution ecological effect. The method solves the problems that according to an existing ecological effect evaluation method, single-species acute toxicity data obtained on the basis of laboratory tests is not suitable for field actual pollution ...

Looped network protection method for transmitting multiprotocol label switching network

The invention relates to a ring network protection method for transmitting multi-protocol label switching and two ring-shaped communication links of ring network. The method comprises: setting reserved label as protection label of Ring network, configuring all node of Ring network as straight-through Ring network protection label; when the node is needed bridging, modifying the node configuration to push the failure service to ring network protection label tunnel; when node is needed inverting, modifying the node configuration as popping the failure service out of the ring network protection label tunnel; when failure of ring network is removed, restoring the node configuration of ring network to straight-through ring network protection label. The inventive method effectively solves problem of ring network WRAPPING protection service expansion for PTN equipment, saves fussy configuration management, and effectively utilizes label tunnel idea.

Welding tool for manufacturing metal corrugated pipe for transformer

The invention discloses a transformer metal corrugated pipe manufacturing welding tool which comprises a base, a lifting frame and a clamping frame are fixedly installed at the top of the base, a limiting frame is fixedly installed at the top of the lifting frame, and a plurality of first electric hydraulic rods are fixedly installed at the top of the base. According to the scheme, on the specific welding tool, the metal corrugated pipe and the flange plate can be directly welded conveniently, the width of the flange plate can be more effectively determined between the limiting plate and the inner wall of the limiting frame through sliding of the arranged limiting plate in the limiting frame, and the flange plate can be more stably welded through movement of the lifting rod along with the limiting plate. And the preheating frame and the flat arc frame can conduct preheating and flat arc operation on the tail end of the metal corrugated pipe according to the width of the flange plate, so ...

Yellow cartfish adult feedstuff

Polyester resin for low-cost and high-leveling powder coating and preparation method of polyester resin

The invention relates to a low-cost and high-leveling polyester resin for a powder coating, which is obtained by polymerizing the following main raw materials: refined kitchen waste oil, trimethylolpropane, 1, 2, 6-hexanetriol, triethylene glycol, isophthalic acid, brazil acid, terephthalic acid and adipic anhydride. The chain segment of the finally obtained polyester resin contains a large amount of C16-C18 esterification groups, the product has excellent water resistance and a low softening point which is basically 90-100 DEG C, the triglyceride component of the refined kitchen waste oil is comprehensively utilized, the cost is low, the terminal carboxyl group steric hindrance of the polyester resin is small, the activity is high, and after the polyester resin and E-12 are finally cured at a low temperature of 160 DEG C/15 min, the polyester resin has excellent water resistance and a softening point which is basically 90-100 DEG C; the obtained 60/40 polyester resin coating film has an ...

Plastic surface printing ink and preparation method thereof

The invention discloses a plastic surface printing ink. The printing ink comprises the following raw materials in percentages by weight: 20-30% of alcohol-soluble polyamide resin solution, 1-5% of nitrocotton resin solution, 10-32% of pigment titanium dioxide, 1-5% of filler, 0.2-1% ofpolyethylene wax, 0.5-1.5% of erucyl amide, 0.1-0.5% of additive, 1-2% of dimethyl phthalate, 10-30% of ethyl acetate, 10-30% of ethanol and 10-30% n-propyl acetate. The invention takes full advantage of the characteristic that the modified polyamide resin can be dissolved in alcohol, the obtained alcohol-soluble polyamide resin solution effectively forms affinity to nitrocotton resin with a low molecular weight structure and has a good compatibility, so that a good leveling is realized during the printing process and the ink with high solid content can be prepared. The printing viscosity of the ink can be diluted to 12 seconds, the ink is adapted to printing machine speed of above 350 meter per minute, and ...

Automatic intelligent winding displacement control system for production of optical fibers and cables

The invention discloses an automatic intelligent winding displacement control system for production of optical fibers and cables. The system comprises a frame, a mobile motor, a rotary motor, a mounting base, and a mechanical arm. A screw embedded into a screw nut is mounted between front and rear bearing blocks, the screw nut is fixed to the mounting base, and the mobile motor is mounted at one end of the screw. The mounting base includes a horizontal base plate and a side plate, a front pressure roller and a rear pressure roller are mounted on the outer side face of the side plate, and a base block with a through hole is mounted on the horizontal base plate through a rotating mechanism. One end of the mechanical arm is provided with a gear along the circumference, two front guide rollers arranged up and down and two rear guide rollers arranged up and down are mounted at the other end of the mechanical arm, and an infrared sensor is arranged between the front guide rollers and the rear ...

Linear protection switching method applicable to large-capacity PTN (packet transport network) device

The invention relates to a linear protection switching method applicable to a large-capacity PTN (packet transport network) device. At a communication source end node, output ports are configured by a crossed unit into three service forwarding instances, namely a main NNI (network node interface) port, a standby NNI port, and a main-standby NNI port; keywords matched to generate target MAC (media access control) addresses, namely MACn1, MACn2, and MACn3; at a communication destination end node, the interface units of the main and standby NNI interfaces are respectively configured with service processing instances; and the keyword to be matched is a Tunnel label; however, only the main service instance is in activated state; during switching, corresponding switching operations are implemented according to protection modes (1-plus-1 protection and 1-to-1 protection). The most fundamental thought of the linear protection switching method applicable to the large-capacity PTN (packet transport ...

BROWN GREASE TREATMENT PROCESSES

Provided herein is a process for rapidly reclaiming brown grease from a source of brown grease. In particular, the process comprises simultaneously transporting and heating the source of brown grease through a heated metal pipeline, and separating the lipid component comprising brown grease from other components in the source of brown grease. Also provided is a method for preparing a biodiesel solution from a lipid mixture comprising brown grease.

Inflammatory factor receptor antagonist of microbial source and preparation method thereof

The invention relates to an inflammatory factor receptor antagonist of a microbial source and a preparation method thereof, wherein the inflammatory factor receptor antagonistic activator is a tumor necrosis factor receptor (TNFR) antagonist A which has a form A1 and a form A2. The invention also relates to a beauveria bassiana A1 for generating the TNFR antagonist A. The invention also relates to an application of the TNFR antagonist A for preparing medicaments for treating diseases related to excess of natural TNFR ligands.

SUBSTITUTED PROLINES / PIPERIDINES AS OREXIN RECEPTOR ANTAGONISTS

Application of miR-27a-3p expression inhibitor in preparation of medicine for treating pulmonary arterial hypertension

The invention provides an application of a miR-27a-3p expression inhibitor in preparation of a medicine for treating pulmonary arterial hypertension. The medicine comprises the miR-27a-3p expression inhibitor. The miR-27a-3p expression inhibitor is a miR-27a-3p antisense single-stranded oligonucleotide or a miR-27a-3p gene knockout vector, and the preferable sequence of the miR-27a-3p antisense single-stranded oligonucleotide is SEQ ID NO: 3. The invention verifies that knock-down of the miR-27a-3p can inhibit proliferation and migration of pulmonary artery endothelial cells (PAECs) and promote apoptosis and death of the PAECs so as to reverse remodeling of pulmonary vessels, so that the miR-27a-3p can be used as a drug target for treating pulmonary hypertension.

Work piece transferring and hanging method and device based on overrunning clutch race

The invention discloses a work piece transferring and hanging method and a device based on an overrunning clutch race. The work piece transferring and hanging method comprises the following processes: a process in which a prying body and a work piece are transferred and moved downwardly on a first race through a roller with the overrunning clutch device while being hung to a hanging chain simultaneously; a process in which the changing chain transfers the prying body and the work piece; and a process in which the prying body and the work piece on the hanging chain are lowered onto a roller with the overrunning clutch device on a second race. Compared with the other transferring and hanging mode, the method has the characteristics and advantages of high production efficiency, low cost, short equipment purchase cycle, simple installation, safety and reliability, and continuous production realization.

Multi-purpose material intelligent square cabin and using method thereof

The invention discloses a multipurpose material intelligent shelter and a using method thereof.The main body comprises a folding base, a strip-shaped foundation bottom plate is arranged in the middle of the folding base, folding turning plates are arranged on the two sides of the strip-shaped foundation bottom plate, a rectangular shelter body is arranged at the top end of the folding base, an arc-shaped dome is arranged at the top end of the rectangular shelter body, and a light-transmitting assembly is arranged above the arc-shaped dome; a ventilation assembly is arranged at one end of the rectangular square cabin, the inner side of the rectangular square cabin is divided into a material management cabin and a control cabin through a partition baffle, emergency exits are formed in the two sides of the rectangular square cabin respectively, a monitoring control terminal, a material management terminal and a power distribution terminal are arranged on the inner wall of the control cabin ...

Thermal power generating unit denitration control method based on deep neural network

The invention discloses a thermal power generating unit denitration control method based on a deep neural network, and belongs to the field of thermotechnical automatic control. A deep neural network is utilized to establish models of boiler total coal quantity, coal quality coefficient, urea pyrolyzing furnace temperature, SCR inlet flue gas temperature, flue gas flow and the like on the NOx concentration of clean flue gas, and the required urea flow is calculated according to the models, so that the NOx concentration of the clean flue gas is accurately adjusted, and the economical efficiency of the denitration process is improved. According to the modeling method provided by the invention, the required adjustment parameters are few, the practicability is high, and the accuracy of the model is improved.

Photothermal conversion absorbing membrane system and sol-gel preparation method thereof

The invention provides a photothermal conversion absorbing membrane system and a sol-gel preparation method thereof, wherein the photothermal conversion membrane system is a three-layer structure consisting of two layers of alumina-based absorbing membranes with gradually changed ingredients on a metal substrate and an antireflective top layer; the two layers of alumina-based absorbing membranes with gradually changed ingredients adopt M-Al2O3 mixed sol with high metal content for the preparation of an absorbing bottom layer and adopts M-Al2O3 mixed sol with medium metal content for the preparation of an absorbing intermediate layer; the M represents the metal source in transition metal inorganic salts or transition metal organic salts; and the membrane system is prepared by sol-gel method. The photothermal conversion membrane system of the invention is low in cost and simple in preparation method, causes no environmental pollution and has high solar photothermal conversion efficiency.

Skin cream using cationic emulsifier composition and preparation method thereof

The invention relates to the technical field of daily chemicals, in particular to skin cream using a cationic emulsifier composition and a preparation method of the skin cream. The cationic emulsifier composition is firstly prepared, the cationic emulsifier composition is safe, non-irritating and excellent in emulsifying capacity within the application range, the skin cream is further prepared through the cationic emulsifier composition, and the product is safe, non-irritating, good in stability and free of irritation. And the anti-sand skin-care product has the characteristics of sand resistance, long-acting moisture retention and soft and smooth skin feeling, and is a resident skin-care product with excellent performance.

Substituted prolines/piperidines as orexin receptor antagonists

The present invention is directed to compounds that modulate the bioactivity of an orexin receptor such as OX1 or OX2, or both; to pharmaceutical compositions and combinations comprising a compound of the invention; to methods of treatment of malconditions in patients wherein modulation of an orexin receptor is medically indicated; and to methods of preparation of compounds of the invention. For example, orexin receptor-modulatory compounds of the present invention can be used in treatment of an eating disorder, obesity, alcoholism or an alcohol-related disorder, drug abuse or addiction including addiction to cocaine, opiates, amphetamines, or nicotine, a sleep disorder, a cognitive dysfunction in a psychiatric or neurologic disorder, depression, anxiety, panic disorder, schizophrenia, Alzheimer's disease, Parkinson's disease, Huntington's chorea, headache, migraine, pain, gastrointestinal diseases, epilepsy, inflammations, immune-related diseases, endocrine-related diseases, cancer, hypertension ...

Air separation method capable of being matched with cold energy supply in receiving station

The invention discloses an air separation method capable of being matched with cold energy supply in a receiving station. The method includes the following steps that when LNG supply is sufficient, nitrogen from an air separation system is compressed many times and then exchanges heat with LNG, high-pressure supercooling liquid nitrogen can be obtained, and cooling capacity is provided for the air separation system; a stream of liquid nitrogen is extracted from the high-pressure supercooling liquid nitrogen and throttled and then exchanges heat with second stream of raw material air, the temperature of the liquid nitrogen rises so that low pressure nitrogen can be generated, the low pressure nitrogen is added into the nitrogen exchanging heat with the LNG, the temperature of the second stream of raw material air is lowered so that liquid air can be generated through liquidation, and the liquid air forms stock liquid air; when LNG supply is not sufficient, the stock liquid air is fed into ...

Medium-strength-grade high-performance concrete using volcanic ash as admixture

The invention relates to a medium-strength-grade high-performance concrete using volcanic ash as an admixture. The workability and durability of the concrete can meet the index requirements for high-performance concrete. In every cubic meter of the concrete, the cementing material weighs 320-380kg. The cementing material comprises the following components in percentage by weight: 65-68% of cement, 30% of volcanic ash and 2-5% of siliceous dust. When preparing the concrete, a polycarboxylic-acid high-efficiency water reducing agent, which accounts for 0.8-1.0% by weight of the cementing material, is added. The workability and durability of the concrete can meet the index requirements for high-performance concrete, and can completely satisfy the requirement of slump for pump concrete, thereby providing an effective technical way for preparation of project-site maximum-size medium-strength-grade concrete by using volcanic ash as an admixture as well as development and utilization of volcanic ...

Car lamp shell injection molding equipment

The invention discloses vehicle lamp shell injection molding equipment which comprises an injection molding assembly, a first injection molding assembly and a second injection molding assembly, the injection molding assembly comprises an injection molding machine body, a blanking pipe, a mixing barrel, a first motor and a stirring rod, the blanking pipe is located on the injection molding machine body, the mixing barrel is fixed to the top of the blanking pipe, the first motor is arranged at the top of the mixing barrel, and the stirring rod is fixed to an output shaft of the first motor; the anti-blocking assembly comprises a quantifying part, a blocking part, a locking part, a dredging part and a triggering part, the quantifying part is located in the discharging pipe, the blocking part is arranged on one side of the quantifying part, the blocking part is located on one side of the quantifying part, and the locking part is arranged on the blocking part. The electric vehicle shell injection ...

Wideband amplifier tuning

Circuits and methods using a single low noise amplifier (LNA) to provide broadband amplification of RF frequencies while maintaining high gain and low noise factors. Embodiments include an amplifier circuit comprising: an input signal path for receiving a broadband RF signal; a switched inductor tuning block coupled to the input signal path and configured to selectively couple one of the plurality of inductors to the input signal path; and an amplifier coupled to the switching inductor tuning block and configured to receive the RF signal after the RF signal passes through the selected coupling inductance. The switched inductor tuning block comprises a plurality of selectable branches, each selectable branch comprising: an RF input switch; an RF output switch; an inductor coupled between the RF input switch and the RF output switch; and a first shunt switch and a second shunt switch coupled between respective terminals of the inductor and a circuit ground.

Method and system for converting video file into SWF file

The invention relates to a method for converting video files into SWF files, comprising the following steps: extracting related parameter values of a source video file, and calculating related parameter values of a main SWF file required to be generated on the basis of the extracted related parameter values; converting the source video file into at least one FLV file; generating at least one sub SWF file according to the calculated related parameter values of the main SWF file, and respectively embedding the FLV file into each sub SWF file; generating one main SWF file according to the calculated related parameter values of the main SWF file, and adding the at least one sub SWF file into the main SWF file frame by frame; adding play rules into the main SWF file; and storing and outputtingthe main SWF file. The invention also discloses a system using the method. By utilizing the method and the system of the invention, not only the standard format of Flash files are not destroyed, but also ...

Compound acidulant

The invention relates to a method for preparing a compound acidulant, characterized by comprising the following steps: component ratio being based on the weigh percentage: firstly crushing anhydrous citric acid, rhizome corydalis acid, calcium lactate, potassium diformate and butanoic acid in an all-purpose grinder, screening with 60 mesh sieve, putting white carbon black in a double-shaft paddle type efficient mixer, spraying lactic acid in the mixer for mixing by a pump, enabling the white carbon black to coat all the lactic acid; then adding the anhydrous citric acid, the rhizome corydalis acid, the calcium lactate, the potassium diformate, the butanoic acid and siliceous earth into the mixer for mixing; finally adding bacillus licheniformis and dipeptide glycyl-glutamine into the mixer and mixing into a finished product. Compared with the inorganic acidulant, the lactic acid type acidulant has more remarkable effect of lactic acidulant, can better improve the intestinal microflora because ...

4'-substituted nucleoside derivatives as inhibitors of hcv rna replication

The present invention relates to the use of nucleoside derivatives of formula I wherein B signifies a 9-purinyl residue B1 of formula or a 1-pyrimidyl residue B2 of formula wherein the symbols are as defined in the specification, and of pharmaceutically acceptable salts thereof; for the treatment of diseases mediated by the Hepatitis C Virus (HCV), for the preparation of a medicament for such treatment and to pharmaceutical compositions containing such compounds.

Sulfonamide, sulfamate, and sulfamothioate derivatives

The disclosure provides biologically active compounds of formula (I): and pharmaceutically acceptable salts thereof, compositions containing these compounds, and methods of using these compounds in a variety applications, such as treatment of diseases or disorders associated with E1 type activating enzymes, and with Nedd8 activating enzyme (NAE) in particular.

ARYLSUBSTITUTED THIAZOLOTRIAZOLES AND THIAZOLOIMIDAZOLES

This disclosure relates to compounds, compositions and methods for the treatment of various disorders. In particular, the disclosure relates to thiazolotriazole and thiazoloimidazole compounds which agonize the activity of the protein TGR5. 10. A compound according to claim 1 , wherein{'sub': 1', '2', '1', '6', '1', '6', '2', '1', '6', '1', '6', '2', '1', '6', '1', '6', '1', '6', '1', '6', '1', '6', '1', '6', '2', '2', '2', '7, 'Ris hydrogen, halogen, —NO, —CN, C-Calkyl, C-Chaloalkyl, —NH, —NH(C-Calkyl), —N(C-Calkyl), —OH, C-Calkoxy, C-Chaloalkoxy, aryl, aryl C-Calkyl, aryl C-Calkenyl, heteroaryl, heteroaryl C-Calkyl, —CON(C-Calkyl)-aryl, —CONH-aryl, —O—CH-aryl, —NH—CH-aryl, or —S—CH-aryl, wherein each is optionally substituted at any suitable position with one or more of R.'}11. A compound according to claim 10 , wherein Ris hydrogen claim 10 , halogen claim 10 , —NO claim 10 , —CN claim 10 , C-Calkyl claim 10 , C-Chaloalkyl claim 10 , —NH claim 10 , —NH(C-Calkyl) claim 10 , —N(C-Calkyl) claim 10 , —OH claim 10 , C-Calkoxy claim 10 , C-Chaloalkoxy claim 10 , aryl claim 10 , aryl C-Calkyl claim 10 , aryl C-Calkenyl claim 10 , heteroaryl claim 10 , or heteroaryl C-Calkyl claim 10 , wherein each is optionally substituted at any suitable position with one or more of R.12. A compound according to claim 11 , wherein Ris hydrogen claim 11 , halogen claim 11 , C-Calkyl claim 11 , aryl claim 11 , aryl C-Calkyl claim 11 , aryl C-Calkenyl claim 11 , heteroaryl claim 11 , or heteroaryl C-Calkyl claim 11 , wherein each is optionally substituted at any suitable position with one or more of R.13. A compound according to claim 12 , wherein Ris hydrogen claim 12 , halogen claim 12 , or C-Calkyl.14. A compound according to claim 13 , wherein Ris hydrogen.15. A compound according to claim 12 , wherein Ris aryl claim 12 , aryl C-Calkyl claim 12 , or aryl C-Calkenyl claim 12 , wherein each is optionally substituted at any suitable position with one or more of R.16. A compound according ...

SUBSTITUTED PYRIMIDINYL-AMINES AS PROTEIN KINASE INHIBITORS

The present invention provides novel substituted pyrimidinyl-amines that are useful as inhibitors of protein kinases, especially c-Jun N-terminal kinases (JNK) and pharmaceutical compositions thereof and methods of using the same for treating conditions responsive to the inhibition of the JNK pathway. 128.-. (canceled)3037.-. (canceled)39. The method of claim 29 , wherein the compound is selected from the group consisting of Examples 1 claim 29 , 4-25 claim 29 , 27-43 claim 29 , 45-47 claim 29 , 49-55 claim 29 , 57 claim 29 , 59 claim 29 , 72-77 claim 29 , 79-85 claim 29 , 89-94 claim 29 , 96 claim 29 , 98-101 claim 29 , 103 claim 29 , 105-119 claim 29 , 121 claim 29 , 122 claim 29 , 125-174 claim 29 , and 176-337.40. The method of claim 29 , wherein the compound is selected from the group consisting of Examples 2 claim 29 , 3 claim 29 , 26 claim 29 , 44 claim 29 , 48 claim 29 , 56 claim 29 , 58 claim 29 , 60 claim 29 , 61 claim 29 , 78 claim 29 , 86 claim 29 , 87 claim 29 , 88 claim 29 , 95 claim 29 , 97 claim 29 , 102 claim 29 , 104 claim 29 , 120 claim 29 , 123 claim 29 , 124 claim 29 , and 175.41. The method of claim 29 , wherein for the compound of formula (Ic) claim 29 ,{'sup': 1', '2, 'Zand Zare each CH;'}{'sup': 1', '5, 'sub': 'q', 'Ris 4- to 10-membered heterocyclic ring having 1 to 4 heteroatom ring members selected from O, S(O), and N, wherein the heterocyclic ring is substituted with 0-2 R;'}{'sup': 2', 'a', 'a', 'a', 'a, 'sub': 3', '3', '1-4', '2-4', '2-4', '2', '2', '2, 'R, when present, is independently Cl, F, Br, I, CF, OCF, Calkyl, Calkenyl, Calkynyl, NO, —CN, OR, N(R), COR, COR;'}{'sup': '3', 'sub': 3', '2', '3, 'Ris H, CH, CHCH, cyano, Cl, F, Br, or I;'}{'sup': 4', '4a, 'Ris a phenyl ring substituted with 1-2 Rgroups;'}{'sup': 4a', '5', '5', '5', '5a', '4a', '5a, 'sub': 3', '3', '1-6', '2-6', '2-6', '2', 'p', '2', '2', 'p', '2', 'p', '2', 'p', '2', '2', 'p', '2', 'p', '2', 'p', '2', '2', 'p', '2', '2', 'p', '2', '2', 'p', '2', 'p', '2', '2', 'p', ...

4'-SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION

The present invention relates to the use of nucleoside derivatives of formula Ia 2. A pharmaceutical composition comprising a compound according to admixed with at least one carrier claim 1 , diluent or excipient. This application is a continuation of U.S. Ser. No. 13/274,743 filed Oct. 17, 2011, which is a divisional of U.S. Ser. No. 12/561,097 filed Sep. 16, 2009, which is a divisional of U.S. Ser. No. 10/891,967 filed Jul. 15, 2004, which is a divisional of Ser. No. 10/167,106, filed Jun. 11, 2002, now issued as U.S. Pat. No. 6,784,166 granted Aug. 31, 2004, which claims benefit under Title 35, United States Code, §119 of Great Britain Patent Application No. 00114286.8, filed on Jun. 12, 2001.The invention relates to nucleoside derivatives as inhibitors of HCV replicon RNA replication. In particular, the invention is concerned with the use of purine and pyrimidine nucleoside derivatives as inhibitors of subgenomic Hepatitis C Virus (HCV) RNA replication and pharmaceutical compositions containing such compounds.Hepatitis C virus is the leading cause of chronic liver disease throughout the world. Patients infected with HCV are at risk of developing cirrhosis of the liver and subsequent hepatocellular carcinoma and hence HCV is the major indication for liver transplantation. Only two approved therapies are currently available for the treatment of HCV infection (R. G. Gish, Sem. Liver. Dis., 1999, 19, 35). These are interferon-α monotherapy and, more recently, combination therapy of the nucleoside analogue, ribavirin (Virazole), with interferon-α.Many of the drugs approved for the treatment of viral infections are nucleosides or nucleoside analogues and most of these nucleoside analogue drugs inhibit viral replication, following conversion to the corresponding triphosphates, through inhibition of the viral polymerase enzymes. This conversion to the triphosphate is commonly mediated by cellular kinases and therefore the direct evaluation of nucleosides as inhibitors ...

Two-Stage LNA with Mutual Coupling

Compact low noise amplifiers that have wide-band coverage while meeting necessary input matching and output matching characteristics. Embodiments include a wide-band, two-stage LNA with minimum degradation in performance compared to multiple narrow-band, single-stage LNAs. A generalized embodiment includes a first amplifier stage having a terminal coupled to a mutually coupled inductor circuit and to a second amplifier stage. The second amplifier stage includes a terminal coupled to the mutually coupled inductor circuit. The mutually coupled inductor circuit comprises electromagnetically coupled inductors L, L. Second terminals of the first and second amplifier stages are coupled to respective degeneration inductors. The electromagnetically coupled inductors L, L of the inductor circuit substantially increase the output bandwidth of the LNA with minimum degradation in performance. 1. A low noise amplifier , including:(a) a first amplifier stage having an input configured to receive a radio frequency (RF) input signal, and an output for an amplified RF signal;(b) a second amplifier stage having an input configured to receive the amplified RF signal from the first amplifier stage, and an output for a further amplified RF signal; (1) a first inductor coupled to the output of the first amplifier stage and configured to be coupled to a first supply voltage; and', '(2) a second inductor coupled to the output of the second amplifier stage and configured to be coupled to a second supply voltage;, '(c) an inductor circuit includingwherein the first inductor and the second inductor are electromagnetically coupled such that a mutual coupling factor K exists between the first inductor and the second inductor of the inductor circuit.2. The invention of claim 1 , wherein the mutual coupling factor K is equal to or greater than about −0.5 and less than or equal to about +0.5.3. The invention of claim 1 , wherein the mutual coupling factor K is equal to or greater than about −0.3 ...

HYPOSIALYLATION DISORDERS

Methods are disclosed for diagnosing a hyposialylation disorder. Methods are also disclosed for determining the effectiveness of a therapeutic agent for treatment of a hyposialylation disorder in a subject. These methods include measuring an amount of monosialylated Thomsen-Friedenreich (ST) antigen and measuring an amount of non-sialylated Thomsen-Friedenreich antigen (T) in a biological sample, such as a serum or plasma sample from the subject, and determining the ratio of T to ST. 1. A method for diagnosing a hyposialylation disorder in a subject , comprisingmeasuring an amount of monosialylated Thomsen-Friedenreich (ST) antigen and measuring an amount of non-sialylated Thomsen-Friedenreich antigen (T) in a biological sample from the subject, wherein Thomsen-Friedenreich antigen is N-acetylgalactosamine (GalNAc) linked to galactose (Gal); anddetermining the ratio of T to ST;wherein a ratio of T to ST of about 0.052 or greater diagnoses the subject as having the hyposialylation disorder.2. The method of claim 1 , further comprising administering to the subject a therapeutic agent for the treatment of the hyposialylation disorder if the ratio of T to ST is greater than about 0.052.3. The method of claim 1 , wherein a ratio of T to ST of about 0.06 or greater diagnoses the subject as having the hyposialylation disorder.4. The method of claim 3 , further comprising administering to the subject a therapeutic agent for the treatment of the hyposialylation disorder if the ratio of T to ST is greater than about 0.06.5. A method of determining the effectiveness of a first dosage of a therapeutic agent for treatment of a hyposialylation disorder in a subject claim 3 , comprisingmeasuring monosialylated Thomsen-Friedenreich (ST) antigen and measuring non-sialylated Thomsen-Friedenreich antigen (T) in a biological sample from the subject, wherein Thomsen-Friedenrich antigen is N-acetylgalactosamine (GalNAc) linked to galactose (Gal); anddetermining the ratio of T to ST; ...

HANGING MODULE

A hanging module includes a fixing rod, a support arm, a plurality of fasteners, and a hanging assembly positioned on the support arm by the plurality of fasteners. The support arm is fixed to the fixing rod. The support arm defines a groove. The hanging assembly includes a locking member and a hanging member fixed to the locking member. The hanging member is received in the groove, and fixed to the locking member by the plurality of fasteners. 1. A hanging module , comprising:a fixing rod;a support arm fixed to the fixing rod, the support arm defining a groove;a plurality of fasteners; anda hanging assembly positioned and fixed on the support arm by the plurality of fasteners, the hanging assembly comprising a locking member and a hanging member fixed to the locking member, the hanging member received in the groove of the support arm, and fixed to the locking member by the plurality of fasteners.2. The hanging module of claim 1 , wherein the hanging member comprises a position portion and at least one extension portion extending from the position portion claim 1 , the position portion is mounted in the groove of the support arm claim 1 , and is fixed to the locking member.3. The hanging module of claim 2 , wherein a number of the at least one extension portion is two claim 2 , and the two extension portions substantially perpendicularly extend from opposite ends of the position portion away from the fixing rod.4. The hanging module of claim 1 , wherein the fixing rod comprises a rod body claim 1 , a first sliding portion claim 1 , and a second sliding portion claim 1 , the first sliding portion and the second sliding portion are positioned at opposite ends of the rod body claim 1 , a substantially middle portion of the support arm is substantially perpendicularly fixed to the rod body.5. The hanging module of claim 1 , wherein the support arm comprises a main body and at least one mounting portion extending from the main body claim 1 , the groove is defined on the ...

Wideband Amplifier Tuning

Circuit and methods using a single low-noise amplifier (LNA) to provide amplification for a wide band of RF frequencies while maintaining high gain and a low noise factor. Embodiments include an amplifier circuit including an input signal path for receiving a wideband RF signal; a switched inductor tuning block coupled to the input signal path and configured to selectively couple one of a plurality of inductances to the input signal path; and an amplifier coupled to the switched inductor tuning block and configured to receive the RF signal after passage through the selected coupled inductance. The switched inductor tuning block includes a plurality of selectable branches, each including an RF input switch; an RF output switch; an inductor coupled between the RF input switch and the RF output switch; and first and second shunt switches coupled between a respective terminal of the inductor and circuit ground. 1. An amplifier circuit including:(a) an input signal path for receiving a wideband radio frequency (RF) signal;(b) a switched inductor tuning block coupled to the input signal path and configured to selectively couple at least one of a plurality of inductances in series with the input signal path; and(c) at least one amplifier, each amplifier having an input coupled to the switched inductor tuning block and configured to receive the RF signal after passage through a selected one of the plurality of inductances, and an output for providing an amplified version of the RF signal.2. The invention of claim 1 , wherein the switched inductor tuning block includes a plurality of selectable branches claim 1 , each branch including:(a) an RF signal input switch;(b) an RF signal output switch;(c) an inductor coupled between the RF signal input switch and the RF signal output switch;(d) a first shunt switch coupled between a first terminal of the inductor and circuit ground; and(e) a second shunt switch coupled between a second terminal of the inductor and circuit ground.3. ...

TURNOVER MECHANISM

A turnover mechanism is used for turning a fixture and a workpiece positioned on the fixture, which includes a support bracket, a first turning mechanism, a movement mechanism, and a second turning mechanism. First turning mechanism includes a first rotary driver, a first clamping driver and two first clamping members oppositely positioned on the first clamping driver. The first rotary driver is positioned on the support bracket and connected to the first clamping driver. The first clamping driver drives the first clamping members to clamp the fixture and the workpiece. The first rotary driver rotate the first clamping driver and the two first clamping members to such that the fixture is driven to be rotated on a reverse side. The movement mechanism reaches the first turning mechanism to transfer the workpiece to the second turning mechanism. Second turning mechanism is mounted on the support bracket, clamping and turning the workpiece. 1. A turnover mechanism , configured for respectively turning over a fixture having a workpiece positioned thereon , comprising:a support bracket,a first turning mechanism the first turning mechanism comprises a first rotary driver, a first clamping driver and two first clamping members oppositely positioned on the first clamping driver,an movement mechanism, anda second turning mechanism,wherein the first rotary driver is positioned on the support bracket and connected to the first clamping driver, the first clamping driver is configured to drive the two first clamping members to clamp the fixture and the workpiece, the first rotary driver is configured to rotate the first clamping driver and the two first clamping members, such that the fixture is driven to be turned over on a reversed side thereof, the movement mechanism is capable of reaching the first turning mechanism to suck and transfer the workpiece to the second turning mechanism; the second turning mechanism is mounted on the support bracket for clamping and turning the ...

Passively q-switched fiber laser system and method for fabricating a saturable absorber of the system

A passively Q-switched fiber laser system comprises a pump source and an ring cavity connected with each other. The ring cavity comprises a gain fiber, a directional coupler and a saturable absorber connected in order. The saturable absorber is a quantum-dot polymer composite film, which is fabricated by a simple method comprising steps of: mixing a quantum dot material of lead sulfide (PbS) with a colloidal polymer to form a mixture; and drying the mixture at two different temperatures in two stages respectively. The saturable absorber of the present invention has lower saturating intensity and a plurality of absorption bands comprising 1000 nm to 1100 nm and 1500 nm to 1600 nm. The maximum output power and the maximum pulse energy of the passively Q-switched fiber laser system can be superior to those laser systems using the quantum-dot (QD) polymer composite film as saturable absorber.

WIDEBAND AUXILIARY INPUT FOR LOW NOISE AMPLIFIERS

Methods and devices to implement efficiently an AUX terminal in RF front end receivers using LNAs are described. The described methods implement a smaller number of switches resulting in an overall performance improvement by reducing the noise figure at the input of the LNA. The presented devices can be used in low/high gain and bypass modes and can accommodate an arbitrary number of bands over a wide frequency range. 1. A multiband radio frequency (RF) receiver front end comprising:a plurality of amplifying transistors;a switching block comprising a plurality of switching arrangements, each switching arrangement being in correspondence with a selectable frequency band of a plurality of selectable frequency bands and with an amplifying transistor of the plurality of amplifying transistors;one or more impedance matching inductors, each impedance matching inductor coupling a respective switching arrangement to a respective amplifying transistor, each being matched to a respective selectable RF band, andan auxiliary (AUX) terminal configured to receive a wideband input signal, the AUX terminal being connected to the plurality of amplifying transistors via the switching block.2. The multiband RF receiver front end of claim 1 , wherein the each switching arrangement comprises:a series switch configured to selectively couple the wideband input signal at the AUX terminal to the amplifying transistor of the plurality of transistors.3. The multiband RF receiver front end of claim 2 , wherein the each switching arrangement further comprises:a shunt switch configured to selectively couple the AUX terminal to a reference voltage when the switching arrangement is not selected, to isolate the wideband input signal from the plurality of amplifying transistors.4. The multiband RF receiver front end of claim 3 , wherein: a1) the series switch is in ON state to couple the input signal to the impedance matching inductor, and', 'a2) the shunt switch is in OFF state to decouple the ...

HYPOSIALYLATION DISORDERS

Methods are disclosed for diagnosing a hyposialylation disorder. Methods are also disclosed for determining the effectiveness of a therapeutic agent for treatment of a hyposialylation disorder in a subject. These methods include measuring an amount of monosialylated Thomsen-Friedenreich (ST) antigen and measuring an amount of non-sialylated Thomsen-Friedenreich antigen (T) in a biological sample, such as a serum or plasma sample from the subject and determining the ratio of T to ST. A ratio of T to monosialylated ST of about 0.06 or higher diagnoses the hyposialylation disorder or indicates that the therapeutic agent is not effective for the treatment of the hyposialylation disorder. In other embodiments, a ratio of T to ST less than about 0.06 indicates that the therapeutic agent is effective for the treatment of the hyposialylation disorder, or the subject does not have the hyposialylation disorder. In additional embodiments, these methods can be used to determine the lowest effective dosage of the therapeutic agent of use to treat the subject. 1. A method for diagnosing a hyposialylation disorder , comprisingmeasuring an amount of monosialylated Thomsen-Friedenreich (ST) antigen and measuring an amount of non-sialylated Thomsen-Friedenreich antigen (T) in a biological sample from the subject, wherein Thomsen-Friedenreich antigen is N-acetylgalactosamine (GalNAc) linked to galactose (Gal); anddetermining the ratio of T to ST;wherein a ratio of T to ST of about 0.06 or greater diagnoses the hyposialylation disorder.2. The method of claim 1 , further comprising administering to the subject a therapeutic agent for the treatment of the hyposialylation disorder if the ratio of T to ST is greater than about 0.06.3. A method of determining the effectiveness of a first dosage of a therapeutic agent for treatment of a hyposialylation disorder in a subject claim 1 , comprisingmeasuring monosialylated Thomsen-Friedenreich (ST) antigen and measuring non-sialylated Thomsen- ...

Substituted pyrimidinyl-amines as protein kinase inhibitors

The present invention provides novel substituted pyrimidinyl-amines that are useful as inhibitors of protein kinases, especially c-Jun N-terminal kinases (JNK) and pharmaceutical compositions thereof and methods of using the same for treating conditions responsive to the inhibition of the JNK pathway.

Routing Process Method, Apparatus, and Device

A routing processing method implemented by a first network device, where a plurality of routing processing components run on the first network device and implement a same routing processing function. The method includes obtaining, from the routing processing components, routing processing results based on same input routing information, analyzing the routing processing results to obtain an analysis result, selecting, based on the analysis result, a first routing processing result from the routing processing results, and executing a corresponding action based on the first routing processing result.

Substituted prolines / piperidines as orexin receptor antagonists

The present invention is directed to compounds that modulate the bioactivity of an orexin receptor such as OX 1 or OX 2 , or both; to pharmaceutical compositions and combinations comprising a compound of the invention; to methods of treatment of malconditions in patients wherein modulation of an orexin receptor is medically indicated; and to methods of preparation of compounds of the invention. For example, orexin receptor-modulatory compounds of the present invention can be used in treatment of an eating disorder, obesity, alcoholism or an alcohol-related disorder, drug abuse or addiction including addiction to cocaine, opiates, amphetamines, or nicotine, a sleep disorder, a cognitive dysfunction in a psychiatric or neurologic disorder, depression, anxiety, panic disorder, schizophrenia, Alzheimer's disease, Parkinson's disease, Huntington's chorea, headache, migraine, pain, gastrointestinal diseases, epilepsy, inflammations, immune-related diseases, endocrine-related diseases, cancer, hypertension, behavior disorder, mood disorder, manic depression, dementia, sex disorder, psychosexual disorder, or renal disease.

Terminal Equipment and Emergency Voice Messaging Method

Provided are terminal equipment and an emergency method for leaving a voice message. The terminal equipment includes: a message leaving component, configured to receive a message from a calling party, and record message time and/or caller number information; an emergency monitoring component, configured to monitor a main service, switch off the main service and enable an emergency service under an abnormal circumstance; wherein the message leaving component is configured to receive a message from a calling party, record message time and/or caller number information according to a service provided by the emergency service. The technical solution ensures the basic service of a voicemail. 1. Terminal equipment , comprising:a message leaving component, configured to receive a message from a calling party, and record message time and/or caller number information;further comprising:an emergency monitoring component, configured to monitor a main service, and under an abnormal circumstance, switch off the main service and enable an emergency service;wherein the message leaving component is configured to receive a message from a calling party, and record message time and/or caller number information according to a service provided by the emergency service.2. The terminal equipment as claimed in claim 1 , further comprising:a message listening component, configured to, according to the service provided by the emergency service, guide and prompt a called party to listen to a message received by the message leaving component, and configured to, according to the service provided by the emergency service, play content of the message, the message time and a caller number, and/or record a listening record of the message.3. The terminal equipment as claimed in claim 2 , further comprising:an emergency strategy component, configured to provide an emergency strategy for the message leaving component and the message listening component, wherein the emergency strategy comprises: a ...

Treatment for wounds

Nucleoside derivatives for the treatment of hepatitis c

Use of compounds of formula (I), wherein R1 is hydrogen, hydroxy, alkyl, hydroxyalkyl, alkoxy, halogen, cyano, isocyano or azido; R2 is hydrogen, hydroxy, alkoxy, chlorine, bromine or iodine; R3 is hydrogen; or R?2 and R3¿ together represent =CH¿2?; or R?2 and R3¿ represent fluorine; X is O, s or CH¿2?; a, b, c, d denoting asymmetric carbon atoms each of which is substituted with 4 different substituents; and B signifies a purine base B1 which is connected through the 9-nitrogen of formula (B1), wherein R?4¿ is hydrogen, hydroxyl, alkyl, alkoxy, alkylthio, aryloxy, arylthio, heterocyclyl, NR7R8, halogen or SH; R5 is hydrogen, hydroxy, alkyl, haloalkyl, cycloalkyl, alkoxy, alkylthio, aryl, aryloxy, arylthio, heterocyclyl, heterocyclylamino, halogen, NR?7R8, NHOR9, NHNR7R8¿ or SH; R6 is hydrogen, hydroxy, alkyl, alkoxy, alkylthio, aryloxy, arylthio, heterocyclyl, NR7R8, halogen, SH or cyano; R?7 and R8¿ are independently of each other hydrogen, alkyl, aryl, hydroxyalkyl, alkenylalkyl, alkynylalkyl, cycloalkyl or acyl; R9 is hydrogen, alkyl or aryl; or B signifies an oxidised purine base B2 which is connected through the 9-nitrogen of formula (B2), wherein R?4, R5 and R6¿ are as defined above; or B signifies a purine base B3 which is connected through the 9-nitrogen of formula (B3), wherein R?4 and R6¿ are as defined above; R10 is hydrogen, alkyl or aryl; Y is O, S or NR11; R11 is hydrogen, hydroxy, alkyl, OR9, heterocyclyl or NR?7R8; R7, R8 and R9¿ are as defined above; or B signifies a pyrimidine base B4 which is connected through the 1-nitrogen of formula (B4), wherein Z is O or S; R12 is hydrogen, hydroxy, alkyl, alkoxy, haloalkyl, alkylthio, aryl, aryloxy, arylthio, heterocyclyl, heterocyclylamino, halogen, NR?7R8, NHOR9, NHNR7R8¿ or SH; R13 is hydrogen, alkyl, hydroxyalkyl, alkoxyalkyl, haloalkyl, cycloalkyl or halogen; R?7, R8 and R9¿ are as defined above; or B signifies a pyrimidine base B5 which is connected through the 1-nitrogen of formula (B5), wherein Y, Z ...

Anti-HCV nucleoside derivatives

The present invention comprises novel and known purine and pyrimidine nucleoside derivatives which have been discovered to be active against hepatitis C virus (HCV). The use of these derivatives for the treatment of HCV infection is claimed as are the novel nucleoside derivatives disclosed herein.

Nucleoside derivatives for the treatment of hepatitis c

Use of compounds of formula (I), wherein R1 is hydrogen, hydroxy, alkyl, hydroxyalkyl, alkoxy, halogen, cyano, isocyano or azido; R2 is hydrogen, hydroxy, alkoxy, chlorine, bromine or iodine; R3 is hydrogen; or R?2 and R3¿ together represent =CH¿2?; or R?2 and R3¿ represent fluorine; X is O, s or CH¿2?; a, b, c, d denoting asymmetric carbon atoms each of which is substituted with 4 different substituents; and B signifies a purine base B1 which is connected through the 9-nitrogen of formula (B1), wherein R?4¿ is hydrogen, hydroxyl, alkyl, alkoxy, alkylthio, aryloxy, arylthio, heterocyclyl, NR7R8, halogen or SH; R5 is hydrogen, hydroxy, alkyl, haloalkyl, cycloalkyl, alkoxy, alkylthio, aryl, aryloxy, arylthio, heterocyclyl, heterocyclylamino, halogen, NR?7R8, NHOR9, NHNR7R8¿ or SH; R6 is hydrogen, hydroxy, alkyl, alkoxy, alkylthio, aryloxy, arylthio, heterocyclyl, NR7R8, halogen, SH or cyano; R?7 and R8¿ are independently of each other hydrogen, alkyl, aryl, hydroxyalkyl, alkenylalkyl, alkynylalkyl, cycloalkyl or acyl; R9 is hydrogen, alkyl or aryl; or B signifies an oxidised purine base B2 which is connected through the 9-nitrogen of formula (B2), wherein R?4, R5 and R6¿ are as defined above; or B signifies a purine base B3 which is connected through the 9-nitrogen of formula (B3), wherein R?4 and R6¿ are as defined above; R10 is hydrogen, alkyl or aryl; Y is O, S or NR11; R11 is hydrogen, hydroxy, alkyl, OR9, heterocyclyl or NR?7R8; R7, R8 and R9¿ are as defined above; or B signifies a pyrimidine base B4 which is connected through the 1-nitrogen of formula (B4), wherein Z is O or S; R12 is hydrogen, hydroxy, alkyl, alkoxy, haloalkyl, alkylthio, aryl, aryloxy, arylthio, heterocyclyl, heterocyclylamino, halogen, NR?7R8, NHOR9, NHNR7R8¿ or SH; R13 is hydrogen, alkyl, hydroxyalkyl, alkoxyalkyl, haloalkyl, cycloalkyl or halogen; R?7, R8 and R9¿ are as defined above; or B signifies a pyrimidine base B5 which is connected through the 1-nitrogen of formula (B5), wherein Y, Z ...

4′-substituted nucleoside derivatives as inhibitors of HCV RNA replication.

The present invention relates to the use of nucleoside derivatives of formula I wherein B signifies a 9-purinyl residue B1 of formula or a 1-pyrimidyl residue B2 of formula wherein the symbols are as defined in the specification, and of pharmaceutically acceptable salts thereof; for the treatment of diseases mediated by the Hepatitis C Virus (HCV), for the preparation of a medicament for such treatment and to pharmaceutical compositions containing such compounds.

Antiviral nucleoside derivatives

The present invention relates to nucleoside derivatives for use in the treatment or prophylaxis of hepatitis C virus infections. In particular, the present invention relates to known 2'-deoxy-2'-fluoro nucleoside derivatives and their use as inhibitors of hepatitis C virus (HCV) RNA replication and pharmaceutical compositions of such compounds. The compounds of this invention have potential use as therapeutic agents for the treatment of HCV infections. The present invention describes the use of 2'-deoxy-2'-fluoro nucleoside derivatives of formula I wherein R1 is hydrogen or phosphate and B signifies a 1-pyrimidinyl or 9-purinyl residue of formulae B1, B2, B3 and of pharmaceutically acceptable salts thereof for the treatment of diseases mediated by the hepatitis C virus (HCV) or for the preparation of medicaments for such treatment.

Hcv ns3 protease replicon shuttle vectors

The present invention provides for novel HCV NS3 protease replicon shuttle vectors useful for cloning in HCV polynucleotide sequences from samples of HCV-infected patients and testing the resulting replicons for drug susceptibility.

Bicycle handlebar

Antiviral nucleoside derivatives

4'-substituted nucleosides for the treatment of diseases mediated by the hepatitis c virus

The present invention relates to the use of nucleoside derivatives of formula I wherein B signifies a 9-purinyl residue B1 of formula or a 1-pyrimidyl residue B2 of formula wherein the symbols are as defined in the specification, and of pharmaceutically acceptable salts thereof; for the treatment of diseases mediated by the Hepatitis C Virus (HCV), for the preparation of a medicament for such treatment and to pharmaceutical compositions containing such compounds.

Substituted prolines piperidines as orexin receptor antagonists

NUCLEOSIDS 4 SUBSTITUTED.

LA PRESENTE INVENCION SE REFIERE AL EMPLEO DE DERIVADOS DE NUCLEOSIDOS DE FORMULA I EN DONDE B SIGNIFICA UN RADICAL 9-PURINILO B1 DE FORMULA B1 O UN RADICAL 1-PIRIMIDILO B2 DE FORMULA B2 EN DONDE LOS SIMBOLOS SON COMO SE HA DEFINIDO EN LA ESPECIFICACION, Y DE LAS SALES FARMACEUTICAMENTE ACEPTABLES DE LOS MISMOS; PARA EL TRATAMIENTO DE ENFERMEDADES INDUCIDAS POR EL VIRUS DE LA HEPATITIS C (HCV), PARA LA PREPARACION DE UN MEDICAMENTO PARA DICHO TRATAMIENTO Y PARA COMPOSICIONES FARMACEUTICAS QUE CONTIENEN DICHOS COMPUESTOS. THIS INVENTION REFERS TO THE USE OF NUCLEOSID DERIVATIVES OF FORMULA I WHERE B MEANS A 9-PURINYL RADICAL B1 OF FORMULA B1 OR A 1-PIRIMIDYL RADICAL B2 OF FORMULA B2 WHERE SYMBOLS ARE AS DEFINED IN THE SPECIFICATION AND OF THE PHARMACEUTICALLY ACCEPTABLE SALTS OF THE SAME; FOR THE TREATMENT OF DISEASES INDUCED BY THE VIRUS OF HEPATITIS C (HCV), FOR THE PREPARATION OF A MEDICINAL PRODUCT FOR SUCH TREATMENT AND FOR PHARMACEUTICAL COMPOSITIONS CONTAINING THOSE COMPOUNDS.

Balancer

Shock-absorbing structure of microphone

4'-substituded nucleosides for the treatment of diseases mediated by the hepatitis c virus

The present invention relates to the use of nucleoside derivatives of Formula (I) wherein B signifies a 9-purinyl residue B1 of Formula (B1) or a 1-pyrimidyl residue B2 of Formula (B2) wherein the symbols are as defined in the specification, and of pharmaceutically acceptable salts thereof; for the treatment of diseases mediated by the Hepatitis C Virus (HCV), for the preparation of a medicament for such treatment and to pharmaceutical compositions containing such compounds.

NUCLEOSIDOS 4'SUBSTITUIDOS FOR THE TREATMENT OF DISEASES MEDIATED BY THE VIRUS OF HEPATITIS C.

Empleo de compuestos de fórmula I en donde R es hidrógeno ó -[P(O)(OH)-O]nH y n es 1, 2 ó 3; R1 es alquilo C1-12, alquenilo C2-7, alquinilo C2- 7, haloalquilo, alquilcarbonilo, alcoxicarbonilo, hidroxialqui-lo, alcoxialquilo, alcoxilo, ciano, azido, hidroxi iminometilo, alcoxiiminometilo, halógeno, alquilcarbonilamino, alquilaminocarbonilo, azidoalquilo, aminometilo, alquilaminometilo, dialquilaminometilo o heterociclilo; R2 es hidrógeno, hidroxilo, amino, alquilo C1- 12, hi-droxialquilo, alcoxilo, halógeno, ciano, o azido; R3 y R4 son hidrógeno, hidroxilo, alcoxilo, halógeno o hidroxialquilo, con la condición de que por lo menos uno de R3 y R4 sea hidrógeno; ó R3 y R4 juntos, representan =CH2 ó =N-OH, ó R3 y R4 representan flúor los dos; X es O, S ó CH2; B significa un radical 9-purinilo B1 de formula en donde R5 es hidrógeno, hidroxilo, alquilo, alcoxilo, alquiltio, NHR8, halógeno ó SH; R6 es hidroxilo, NHR8, NHOR9, NHNR8, - NHC(O)OR9'' ó SH; R7 es hidrógeno, hidroxilo,alquilo C1-12, alcoxilo, alquiltio, NHR8, halógeno, SH ó ciano; R8 es hidrógeno, alquilo C1-12, hidroxialquilo, arilcarbonilo ó alquilcarbonilo; R9 es hidrógeno ó alquilo; R9'' es alquilo C1-12 ó B significa un radical 1-pirimidilo B2, de fórmula en donde Z es O ó S; R10 es hidroxilo, NHR8, NHOR9, NHNR8, - NHC(O)OR9'' ó SH; R11 es hidrógeno, alquilo C1-12, hidroxilo, hidroxialquilo, alcoxialquilo, haloalquilo ó halógeno; R8 R9 and R9'' son como se ha definido más arriba; y de las sales farmacéuticamente aceptables de los mismos; para la preparación de un medicamento para el tratamiento de enfermedades inducidas por el virus de la hepatitis C (HCV). Use of compounds of formula I wherein R is hydrogen or - [P (O) (OH) -O] nH and n is 1, 2 or 3; R1 is C1-12 alkyl, C2-7 alkenyl, C2-7 alkynyl, haloalkyl, alkylcarbonyl, alkoxycarbonyl, hydroxyalkyl, alkoxyalkyl, alkoxy, cyano, azido, hydroxy iminomethyl, alkoxyiminomethyl, halogen, alkylcarbonylamino, alkylaminocarbonyl, ...

Substituted pyrimidinyl amines as protein kinase inhibitors

Un compuesto o sal farmacéuticamente aceptable del mismo de fórmula Ib:**Fórmula** donde: Z1 y Z2 son cada uno CH; R1 es anillo heterocíclico de 4-10 miembros que tiene entre 1 y 4 miembros del anillo heteroatómicos seleccionados entre O, S(O)q, y N, donde el anillo heterocíclico está sustituido con 0-2 R5; R2, cuando está presente, es en forma independiente Cl, F, Br, I, CF3, OCF3, C1-4alquilo, C2-4alquenilo, C2-4-alquinilo, NO2, -CN, ORa, N(Ra)2, CORa, CO2Ra; R3 es H, CH3, CH2CH3, ciano, Cl, F, Br, o I; R4 es un anillo fenilo sustituido con 1-2 grupos R4a; cada R4a es en forma independiente >=O, Cl, F, Br, I, CF3, OCF3, C1-6alquilo sustituido con 0-3 R5, C2-6alquenilo sustituido con 0-3 R5, C2-6alquinilo sustituido con 0-3 R5, (CH2)pNO2, (CH2)pCN, (CH2)pOR, (CH2)pN(R)2, (CH2)pCOR, (CH2)pOCOR, (CH2)pCO2R, (CH2)pCON(R)2, (CH2)pOCON(R)2, (CH2)pNRCOR, (CH2)pNRCO2R, (CH2)pNRCON(R)2, (CH2)pC(>=NH)NH2, (CH2)pSO2R, (CH2)pSO2N(R)2, (CH2)pNRSO2R, (CH2)pNRSO2N(R)2, CH(CF3)NH2, o (CH2)p-(anillo heterocíclico de 5-6 miembros que tiene entre 1 y 4 miembros del anillo heteroatómicos seleccionados entre O, S(O)q, y N), donde el anillo heterocíclico está sustituido con 0-3 R5a, donde un primer grupo R4a es un anillo heteroaromático de 5-6 miembros; cada R es en forma independiente H, C1-6alquilo sustituido con 0-2 R5, C2-6alquenilo sustituido con 0-2 R5, C2- 6alquinilo sustituido con 0-2 R5, anillo carbocíclico de 3-10 miembros sustituido con 0-2 R5, o anillo heterocíclico de 5-10 miembros que tiene entre 1 y 4 miembros del anillo heteroatómicos seleccionados entre O, S(O)q, y N, donde el anillo heterocíclico está sustituido con 0-2 R5; o dos R unidos al mismo átomo de N se toman junto con el átomo de nitrógeno al cual están unidos para formar un heterocicloalquilo de 5-8 miembros sustituido con 0-2 R5; cada R5 es en forma independiente >=O, Cl, F, Br, I, CF3, OCF3, C1-4alquilo, C2-4alquenilo, C2-4alquinilo, NO2, -CN, ORa, N(Ra)2, CORa, CO2Ra, CON(Ra)2, NRaCORa, NRaCO2Ra, ...

Amplifier gain-tuning circuits and methods

Circuits and methods for improving the noise figure (NF) of an amplifier, particularly an LNA, in high-gain modes while improving the IIP3 of the amplifier in low-gain modes. The source of an amplifier common-source FET is coupled to circuit ground thorough a degeneration circuit comprising a two-port inductor and a bypass switch coupled in parallel with the inductor. A switched feedback circuit is coupled between the gate of the common-source FET and a feedback node in the amplifier output signal path. During a low gain mode, the inductor is entirely bypassed and the enabled feedback circuit lowers the input impedance of the common-source FET and reduces the gain of the amplifier circuit, essentially eliminating the need for a degeneration inductor. During a high gain mode, the source of the common-source FET is coupled to circuit ground through the inductor and the feedback circuit is disabled. Other gain modes are supported.

Web page content translator

A system, method, and computer readable medium for reformatting web content into a format readable on one or more mobile devices is provided. A user generates a user request for a web page from a mobile device to a proxy server. The proxy server forwards the user request to an origin web server, which returns the requested web page to the proxy server. A conversion engine within the proxy server extracts the desired content from the web page, and reformats the content in accordance with one or more predefined transform methods associated with the one or more mobile devices before transmitting the transformed web page with the desired content to the one or more mobile devices. Secure or unsecure connection provided via a decorated uniform resource locator can be used to connect a mobile device, the proxy server, and an origin web server.

4'-substituted nukleosides

The present invention relates to the use of nucleoside derivatives of formula Ia wherein the symbols are as defined in the specification, and of pharmaceutically acceptable salts thereof and to pharmaceutical compositions containing such compounds.

4 '-substituted nucleosides for the treatment of diseases mediated by hepatitis C virus

Method and system for implementing ip-based vvm

The embodiment of the invention relates to a method and system for implementing an IP based Visual Voice Mail (VVM). The method includes: establishing a Socket connection between a VVM client and a VVM server; and implementing message transmission between the VVM client and the VVM server through the Socket connection. The method and system for implementing an IP based VVM of the embodiment of the invention implement the VVM service through the Socket connection, so that the VVM service can be implemented on an IP based terminal device.

Stable and ion-conductive hydrocarbon-fluorocarbon materials as electrolytes for fuel cells and batteries

A ring-opening metathesis polymer that is grafted with a free-radical initiator is subject to the radical polymerization of a fluoroalkene for the production of an ion- exchange hydrocarbon-fluorocarbon copolymer. The ring-opening metathesis polymer can also undergo a direct fluorination reaction to yield an ion-exchange fluoropolymer. Such ion-conductive hydrocarbon-fluorocarbon copolymers and fluoropolymers are useful in making chlor-alkali cells, fuel cells, flow batteries, electrolyzers, and other electric devices.

Rack for holding workpieces

A rack ( 100 ) configured for holding workpieces is provided. The rack includes a base ( 10 ) and a plurality of fixtures ( 20 ). The base includes two lateral frames ( 14 ) and a fixing frame ( 16 ) fitted between the two lateral frames. Each of the lateral frames includes a first stopper ( 147 ) and a second stopper ( 148 ) mounted thereon. The fixing frame has two fixing poles ( 164 ) parallel to the two lateral frames. Each of the two fixing poles has a plurality of latching means ( 166 ) mounted thereon in line. The plurality of fixtures rotatably engage with the latching means of the fixing frame and are fitted between the first stopper and the second stopper.

Use of 4'-Substituted Nucleosides for the Preparation of Drugs for the Treatment of Diseases Mediated by Hepatitis C Virus (HCV)

The present invention relates to the use of nucleoside derivatives of formula Ia wherein the symbols are as defined in the specification, and of pharmaceutically acceptable salts thereof and to pharmaceutical compositions containing such compounds.

Implantation device

Anti-HCV nucleoside derivatives

The present invention comprises nucleoside derivatives for use in the treatment or prophylaxis of hepatitis C virus infections. In particular, the present invention discloses the novel use of known 2′-deoxy-2′-fluoro nucleoside derivatives as inhibitors of hepatitis C virus (HCV) RNA replication and pharmaceutical compositions of such compounds. The compounds of this invention have potential use as therapeutic agents for the treatment of HCV infections.

Method and system for implementing ip-based vvm

Preparation method of igy for preventing and cure mouth disease and the toothpaste base on the igy

The present invention relates to a preparation method of IgY for preventing and cure mouth disease, and a safe toothpaste containing the IgY.

Wideband auxiliary input for low noise amplifiers

Methods and devices to implement efficiently an AUX terminal in RF front end receivers using LNAs are described. The described methods implement a smaller number of switches resulting in an overall performance improvement by reducing the noise figure at the input of the LNA. The presented devices can be used in low/high gain and bypass modes and can accommodate an arbitrary number of bands over a wide frequency range.

Treatment for wounds

It has been discovered that increasing telomerase activity in cells surrounding a wound has a variety of effects that enhance wound healing. Replication capacity is enhanced, and the mobility of the epithelial cells can be increased by 3-fold or more. Some aspects of the invention relate to agents that increase telomerase activity in cells at the site of the wound, promoting cells to move to the site and restore an epithelial layer and the underlying stratum. Other aspects of the invention relate to compositions comprising epithelial cells in which telomerase activity has been increased, useful as grafts for the treatment of wounds.

4 substituted nucleosides for the treatment of diseases mediated by the hepatitis c virus

NUCLEOSIDES 4 SUBSTITUTED AS INHIBITORS OF HEPATITIS C VIRUS RNA REPLICATION

SE REFIERE AL EMPLEO DE DERIVADOS DE NUCLEOSIDOS DE PURINA Y PIRIMIDINA DE FORMULA I DONDE R ES H, [P(O)(OH)-O]nH; n ES 1-3; R1 ES ALQUILO, ALQUENILO, ALQUINILO, HALOALQUILO, ALQUILCARBONILO, ALCOXICARBONILO, HIDROXIALQUILO, ALCOXIALQUILO, ENTRE OTROS; R2 ES H, HIDROXILO, AMINO, ALQUILO, HIDROXIALQUILO, ALCOXILO, HALOGENO, CIANO, AZIDO; R3 Y R4 SON H, OH, ALCOXILO, HALOGENO, HIDROXIALQUILO; UNO DE R3 Y R4 ES H; O JUNTOS SON =CH2, =NOH, X ES O, S, CH2; B ES 9-PURINILO DE FORMULA B1; R5 ES H, OH, ALQUILO, ALCOXILO, ALQUILTIO, NHR8, HALOGENO, SH; R6 ES HIDROXILO, NHR8, NHOR9, NHNR8, NHCOOR9', SH; R7 ES H, HIDROXILO, ALQUILO, ALCOXILO, ALQUILTIO, NHR8, HALOGENO, SH, CIANO; R8 ES H, ALQUILO, HIDROXIALQUILO, ARILCARBONILO, ALQUILCARBONILO; R9 ES H, ALQUILO; R9' ES ALQUILO; B ES 1-PIRIMIDILO B2; Z ES O, S; R10 ES HIDROXILO, NHR8, NHOR9, NHNR8; NHCOOR9', SH; R11 ES H, ALQUILO, HIDROXILO, HIDROXIALQUILO, ALCOXIALQUILO, HALOALQUILO, ENTRE OTROS. SON COMPUESTOS PREFERIDOS 4'-C-ETINILCITIDINA; 4'-C-ETOXICITIDINA; 4'-C-ACETILCITIDINA, 4'-C-AZIDOCITIDINA, 4'-CIANOCITIDINA, ENTRE OTROS. LOS COMPUESTOS I SON INHIBIDORES DE REPLICACION DEL ARN SUBGENOMICO DEL VIRUS DE HEPATITIS C Y PUEDEN SER UTILES PARA EL TRATAMIENTO DE HEPATITIS C REFERS TO THE USE OF PURINE AND PYRIMIDINE NUCLEOSIDE DERIVATIVES OF FORMULA I WHERE R IS H, [P (O) (OH) -O] nH; n IS 1-3; R1 IS ALKYL, ALKENYL, ALKINYL, HALOALKYL, ALKYLCARBONYL, ALCOXYCARBONYL, HYDROXYALKYL, ALCOXYALKYL, AMONG OTHERS; R2 IS H, HYDROXYL, AMINE, ALKYL, HYDROXYALKYL, ALCOXYL, HALOGEN, CYANE, AZIDO; R3 AND R4 ARE H, OH, ALCOXYL, HALOGEN, HYDROXYALKYL; ONE OF R3 AND R4 IS H; OR TOGETHER THEY ARE = CH2, = NOH, X IS O, S, CH2; B IS FORMULA B1 9-PURINYL; R5 IS H, OH, ALKYL, ALCOXYL, ALKYLTIO, NHR8, HALOGEN, SH; R6 IS HYDROXYL, NHR8, NHOR9, NHNR8, NHCOOR9 ', SH; R7 IS H, HYDROXYL, ALKYL, ALCOXYL, ALKYLTIO, NHR8, HALOGEN, SH, CYANE; R8 IS H, ALKYL, HYDROXYALKYL, ARYLCARBONYL, ALKYLCARBONYL; R9 IS H, ALKYL; R9 ...

Enhancing cell migration by increasing telomerase activity

It has been discovered that increasing telomerase activity in cells surrounding a wound promotes wound healing. Replication capacity is enhanced, and the mobility of the epithelial cells can be increased by 3-fold or more. Particular aspects of the invention described in this disclosure include the use of agents that increase telomerase activity in cells at the site of the wound, promoting cells to move to the site and restore an epithelial layer and the underlying stratum.

A saw machine riving knife adjustment mechanism

Zinc oxide extended gate ion-sensitive field-effect transistor

Revolving axle structure with position-locking engagement means

Digitally printed plate, manufacturing method, and application

This invention discloses digitally printed plate, the manufacturing method and applications thereof, is characterized in that the digitally printed plate is of respectively from top to bottom surface lacquer layer, texture layer, second wear layer, first wear layer, pattern layer, bottom lacquer layer, base layer. The digitally printed plated has various patterns, with sufficient materials, printing unrepeatable stereoscopic pattern is possible, so it can satisfy customers' personalized customization requirements, without wasting abundant time or cost, and with process reduced, production efficiency is improved, enabling order manufacturing order insert and sample making at any time.

Feedback topologies for amplifier gain reduction

Feedback methods and devices to reduce gain in RF amplifiers, more in particular LNAs, are disclosed. The described methods are based on providing feedback paths from the drain terminal of one of the LNA cascode transistors to the source terminal of the LNA input transistor, or from the gate terminal of the input transistor to the source terminal of the LNA input transistor. The disclosed methods can be combined with one another or with existing feedback methods to provide further flexibility and improved tradeoffs when designing LNAs for applications having different requirements.

Two-stage LNA with mutual coupling

Compact low noise amplifiers that have wide-band coverage while meeting necessary input matching and output matching characteristics. Embodiments include a wide-band, two-stage LNA with minimum degradation in performance compared to multiple narrow-band, single-stage LNAs. A generalized embodiment includes a first amplifier stage having a terminal coupled to a mutually coupled inductor circuit and to a second amplifier stage. The second amplifier stage includes a terminal coupled to the mutually coupled inductor circuit. The mutually coupled inductor circuit comprises electromagnetically coupled inductors L1, L2. Second terminals of the first and second amplifier stages are coupled to respective degeneration inductors. The electromagnetically coupled inductors L1, L2 of the inductor circuit substantially increase the output bandwidth of the LNA with minimum degradation in performance.

Sleeve-type rotation shaft structure and sleeve thereof

服務派送伺服器及依據資料內容特徵碼提供服務之控管方法

本發明提供一種服務派送伺服器及依據資料內容特徵碼提供服務之控管方法。該方法包含下列步驟：自一服務要求端接收一服務要求(Service request)，其中該服務要求包含有該資料內容特徵碼以及至少一服務資料，該資料內容特徵碼與該至少一服務資料係對應於一應用服務；依據該服務要求，解析出該資料內容特徵碼與該至少一服務資料；以及將該服務要求傳送給對應該資料內容特徵碼與該至少一服務資料之一處理單元，以允許該處理單元執行該應用服務。

具有咖啡粒之輪胎

具有咖啡粒之輪胎

本發明之具有咖啡粒之輪胎，其胎膠層係至少由原料橡膠形成一固態膠體，且固態膠體佈設複數咖啡粒子，而各咖啡粒子係為具有多微孔隙的結構體。俾可在不影響結構強度之條件下，由具有多微孔隙且主要成分為碳氫化合物之咖啡粒子去除胎膠層之異味，以相對更為積極、可靠之手段，減輕傳統輪胎發出的臭味而讓人感到不適，以及可能產生的毒性反應。

Tires with coffee grains

Amplifiers with attenuator in feedback and bypass paths

Methods and devices to support multiple gain states in amplifiers are described. The methods and devices are based on implementing a feedback element in the amplifier and adjusting the impedance of the feedback element to provide a desired gain while maintaining the overall performance of the amplifier and reducing degradation of the S12 parameter. The feedback element includes an adjustable attenuator and a tunable resistive element. The adjustable attenuator is provided in a path that is common to the feedback path and the bypass path of the amplifier. Exemplary implementations of adjustable attenuators are also presented.

A high performance isocyanate free polyurethane resin coating

A method of preparing a high performance low isocyanate polyurethane top coating effective to protect external architectural surfaces and substantially minimizing applicator exposure to isocyanates, comprising: providing an amount of compound A chosen from a fluoroethylene vinyl ether (FEVE) moiety of formula (I); providing an amount of Compound B chosen from a silane functional isocyanate of general formula (II); wherein the compound A and compound B are present in a stoichiometric ratio of 1:1; providing an effective amount of a catalyst of compound C; introducing the compounds A and B into a reaction vessel and stirring the compounds in an inert atmosphere at a predetermined temperature and a predetermined time; wherein the resultant silane functional FEVE resin is substantially free of unreacted isocyanate.

Wideband amplifier tuning

Circuit and methods using a single low-noise amplifier (LNA) to provide amplification for a wide band of RF frequencies while maintaining high gain and a low noise factor. Embodiments include an amplifier circuit including an input signal path for receiving a wideband RF signal; a switched inductor tuning block coupled to the input signal path and configured to selectively couple one of a plurality of inductances to the input signal path; and an amplifier coupled to the switched inductor tuning block and configured to receive the RF signal after passage through the selected coupled inductance. The switched inductor tuning block includes a plurality of selectable branches, each including an RF input switch; an RF output switch; an inductor coupled between the RF input switch and the RF output switch; and first and second shunt switches coupled between a respective terminal of the inductor and circuit ground.

Numerical simulation optimization method of impact damage based on laser mapped solid mesh

A numerical simulation optimization method of impact damage based on a laser mapped solid mesh is provided, including: measuring an impact damage size, a damage profile, a surface residual strain and a surface residual stress of a solid mesh element around the damage after firing a bullet by a light gas gun to impact a mesh area of a sample and obtaining the impact damage; establishing a parameterized impact finite element model to obtain a numerically simulated impact damage size, a numerically simulated impact damage profile, a numerically simulated surface residual strain and the surface residual stress of the surface solid mesh element; and calculating relative errors between the experimental measurements and the numerically simulated impact damage size, damage profile, surface residual strain and residual stress; and determining whether the relative errors are all less than expected values until a numerical simulation result meeting the accuracy requirements are obtained.

4'-substituierte nukleoside zur behandlung von hepatitis-c-virus-vermittelten erkrankungen

Process of saving water for a flush toilet (1)

Foldable structure for rock-horse

Digitally printed plate, manufacturing method, and application

Disclosed is a digitally printed plate. The digitally printed plate comprises, from top to bottom, a topcoat layer (1), a texture layer (2), a second wear-resistant layer (3), a first wear-resistant layer (4), a pattern layer (5), a primer layer (6), and a substrate layer (7). The digitally printed plate is diversified in pattern, and as long as there are adequate materials, three-dimensional patterns that never repeat can be printed, such that personalized customization requirements of customers can be met, there is no need to spend a lot of time and costs, production procedures are reduced, production efficiency is improved, and order insertion production and proofing can be performed at any time. Also disclosed are a manufacturing method for the digitally printed plate and an application of the digitally printed plate.

Transistor bias adjustment for optimization of third order intercept point in a cascode amplifier

Methods and devices for amplifying an input RF signal according to at least two gain-states is described. According to one aspect, a multi gain amplifier circuit including a low noise amplifier having a stack of transistors is used for amplification of the input RF signal. When switching from a low gain-state to a high gain-state, the drain-to-source voltage of the output transistor of the stack is increased to affect region of operation of the output transistor, and thereby reduce non-linearity at the output of the amplifier. When switching from the high gain-state to the low gain-state, the drain-to-source voltage of the input transistor of the stack is increased to affect region of operation of the input transistor, and thereby reduce non-linearity at the output of the amplifier.

Action companion

Routing information management method and device, and computer storage medium

Method and Apparatus to Optimize Power Clamping

A clamping circuit that may be used to provide efficient and effective voltage clamping in an RF front end. The clamping circuit comprises two series coupled signal path switches and a bypass switch coupled in parallel with the series coupled signal path switches. A diode is coupled from a point between the series coupled signal path switches to a reference potential. In addition, an output selection switch within an RF front end has integrated voltage clamping to more effectively clamp the output voltage from the RF front end. Additional output clamping circuits can be used at various places along a direct gain signal path, along an attenuated gain path and along a bypass path.

欄架結構

Hinge structure with locking/unlocking function

Two-Stage LNA with Mutual Coupling

Compact low noise amplifiers that have wide-band coverage while meeting necessary input matching and output matching characteristics. Embodiments include a wide-band, two-stage LNA with minimum degradation in performance compared to multiple narrow-band, single-stage LNAs. A generalized embodiment includes a first amplifier stage having a terminal coupled to a mutually coupled inductor circuit and to a second amplifier stage. The second amplifier stage includes a terminal coupled to the mutually coupled inductor circuit. The mutually coupled inductor circuit comprises electromagnetically coupled inductors L 1 , L 2 . Second terminals of the first and second amplifier stages are coupled to respective degeneration inductors. The electromagnetically coupled inductors L 1 , L 2 of the inductor circuit substantially increase the output bandwidth of the LNA with minimum degradation in performance.

門扉閉鎖裝置

Feedback topologies for amplifier gain reduction

Feedback methods and devices to reduce gain in RF amplifiers, more in particular LNAs, are disclosed. The described methods are based on providing feedback paths from the drain terminal of one of the LNA cascode transistors to the source terminal of the LNA input transistor, or from the gate terminal of the input transistor to the source terminal of the LNA input transistor. The disclosed methods can be combined with one another or with existing feedback methods to provide further flexibility and improved tradeoffs when designing LNAs for applications having different requirements.

Amplifier Gain-Tuning Circuits and Methods

Circuits and methods for improving the noise figure (NF) of an amplifier, particularly an LNA, in high-gain modes while improving the IIP3 of the amplifier in low-gain modes. The source of an amplifier common-source FET is coupled to circuit ground thorough a degeneration circuit comprising a two-port inductor and a bypass switch coupled in parallel with the inductor. A switched feedback circuit is coupled between the gate of the common-source FET and a feedback node in the amplifier output signal path. During a low gain mode, the inductor is entirely bypassed and the enabled feedback circuit lowers the input impedance of the common-source FET and reduces the gain of the amplifier circuit, essentially eliminating the need for a degeneration inductor. During a high gain mode, the source of the common-source FET is coupled to circuit ground through the inductor and the feedback circuit is disabled. Other gain modes are supported.

噴霧保溫盒結構

Binary redox flow battery for simultaneously charging and discharging electricity

Provided in this patent disclosure are a novel titanium redox flow battery having a nitrogen-enriched catalyst, and a binary redox flow battery comprised of one unit that converts electricity into chemical energy to be stored in electrolytes and a separate second unit that converts the chemical energy from electrolytes back into electricity.

SiC MOSFET Device and Method for Manufacturing the Same

The present application discloses an SiC MOSFET device, including an SiC epitaxial layer in which a trench gate is formed, wherein a first bottom doped region is formed below a bottom surface of a gate trench, a second deep doped region with spacing from the gate trench is formed in the SiC epitaxial layer, the first bottom doped region is connected to a source so that voltage borne by a gate dielectric layer on the bottom surface of the gate trench is determined by gate-source voltage; the second deep doped region extends downward from a top surface of the SiC epitaxial layer, and a bottom surface of the second deep doped region is located below a bottom surface of the first bottom doped region; a top of the second deep doped region is connected to the source. The present application further discloses a method for manufacturing an SiC MOSFET device.

Ion-selecting devic

Supporting wideband inputs on rf receivers

Methods and devices to support multiple frequency bands in radio frequency (RF) circuits are shown. The described methods and devices are based on adjusting the effective width of a transistor in such circuits by selectively disposing matching transistors in parallel with the transistor. The presented devices and methods can be used in RF circuits including low noise amplifiers (LNAs), RF receiver front-ends or any other RF circuits where input matching to wideband inputs is required.

Method and apparatus to optimize power clamping

A clamping circuit that may be used to provide efficient and effective voltage clamping in an RF front end. The clamping circuit comprises two series coupled signal path switches and a bypass switch coupled in parallel with the series coupled signal path switches. A diode is coupled from a point between the series coupled signal path switches to a reference potential. In addition, an output selection switch within an RF front end has integrated voltage clamping to more effectively clamp the output voltage from the RF front end. Additional output clamping circuits can be used at various places along a direct gain signal path, along an attenuated gain path and along a bypass path.

Method and Apparatus to Optimize Power Clamping

A clamping circuit that may be used to provide efficient and effective voltage clamping in an RF front end. The clamping circuit comprises two series coupled signal path switches and a bypass switch coupled in parallel with the series coupled signal path switches. A diode is coupled from a point between the series coupled signal path switches to a reference potential. In addition, an output selection switch within an RF front end has integrated voltage clamping to more effectively clamp the output voltage from the RF front end. Additional output clamping circuits can be used at various places along a direct gain signal path, along an attenuated gain path and along a bypass path.

Routing information transmission method and apparatus, and communication system

Disclosed are a routing information transmission method and apparatus, and a communication system, and belong to the field of communication technologies. The routing information transmission method is applied to a system including data middleware and a routing information base (RIB), and the data middleware communicates with the RIB. The data middleware may obtain routing information from the RIB, and send the routing information obtained from the RIB to a third-party consumer device. In addition, the data middleware may also obtain routing information from a third-party producer device, and send the routing information obtained from the third-party producer device to the RIB. Therefore, according to technical solutions provided herein, the routing information included in the RIB is openly exported, and the routing information generated by the third-party producer device is imported into the RIB.

Method for transmitting routing information, apparatus, and communication system

Embodiments of this application provide a routing information transmission method and apparatus, and a communication system, and belong to the field of communication technologies. The routing information transmission method is applied to a system including data middleware and a RIB, and the data middleware communicates with the RIB. The data middleware provided in embodiments of this application may obtain routing information from the RIB, and send the routing information obtained from the RIB to a third-party consumer device. In addition, the data middleware may also obtain routing information from a third-party producer device, and send the routing information obtained from the third-party producer device to the RIB. Therefore, according to technical solutions provided in embodiments of this application, the routing information included in the RIB is openly exported, and the routing information generated by the third-party producer device is imported into the RIB.