28-12-2017 дата публикации
Номер: US20170369643A1
The invention provides polymer compositions, compounds, processes, and methods of use of the polymers for drug delivery, biodegradable consumer plastics, or solvents for Li-based batteries or supercapacitors. The invention is based, at least in part, on the discovery that poly(glyceric acid carbonate)s and alkyl functionalized poly(1,2 glycerol carbonates) and poly(glyceric acid carbonate)s and pharmaceutical agent/composition functionalized poly(1,2 glycerol carbonates) and poly(glyceric acid carbonate)s represent a new type of glycerol based polymer that 1) degrade into glycerol and carbon dioxide; 2) the poly(1,2 glycerol carbonates) degrade more readily than conventional poly(1,3 glycerol carbonates; and 3) poly(1,2 glycerol carbonates) can be processed to give melts, viscous fluids, liquids, films, sheets, gels, meshes, foams, fibers, or particles. 2. The polymer of claim 1 , wherein Q′ is O.3. The polymer of claim 1 , wherein R′is selected from among hydrogen or a straight or branched alkyl claim 1 , cycloalkyl claim 1 , aryl claim 1 , olefin claim 1 , silyl claim 1 , alkylsilyl claim 1 , arylsilyl claim 1 , alkylaryl or arylalkyl chain of 2-50 carbons claim 1 , wherein each alkyl claim 1 , cycloalkyl claim 1 , succinyl claim 1 , aryl claim 1 , olefin claim 1 , silyl claim 1 , alkylsilyl claim 1 , arylsilyl claim 1 , alkylaryl or arylalkyl chain is optionally substituted internally or terminally by one or more hydroxyl claim 1 , hydroxyether claim 1 , carboxyl claim 1 , carboxyester claim 1 , carboxyamide claim 1 , amino claim 1 , mono- or di-substituted amino claim 1 , thiol claim 1 , thioester claim 1 , sulfate claim 1 , phosphate claim 1 , phosphonate claim 1 , or halogen substituents.4. The polymer of claim 1 , wherein R′is selected from among hydrogen or a straight or branched alkyl claim 1 , cycloalkyl claim 1 , aryl claim 1 , olefin claim 1 , silyl claim 1 , alkylsilyl claim 1 , arylsilyl claim 1 , alkylaryl or arylalkyl chain of 3-50 carbons.5. The ...
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