Настройки

Укажите год
-

Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

Подробнее
-

Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

Подробнее

Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
Ведите корректный номера.
Ведите корректный номера.
Ведите корректный номера.
Ведите корректный номера.
Укажите год
Укажите год
Применить Всего найдено 280. Отображено 100.
12-07-2012 дата публикации

METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING DISEASES

Номер: US20120177659A1
Автор: DOMON Bruno, HE Tao, JOSELOFF Elizabeth G., LEE Candy N., MCKINNON Katherine, MESRI Mehdi, MOORE Paul, RUBEN Steve, VAN ORDEN Karen
Принадлежит: CELERA CORPORATION

Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro. 1. An isolated CAT protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-4 , 9 , 11-12 , 16-19 , 24-36 , 51-59 , 69-74 , 81-85 , 91-102 , 115-116 , 119-121 , 127-134 , 144-145 , 148-149 , 152-159 , 168-174 , and 182-183.2. A composition comprising the CAT protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:5-8, 10, 13-15, 20-23, 37-50, 60-68, 75-80, 86-90, 103-114, 117-118, 122-126, 135-143, 146-147, 150-151, 160-167, 175-181, 184-185;b) nucleotide sequences that encode a CAT protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-4, 9, 11-12, 16-19, 24-36, 51-59, 69-74, 81-85, 91-102, 115-116, 119-121, 127-134, 144-145, 148-149, 152-159, 168-174, and 182-183; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the CAT protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 , or transgenic organism that produces the antibody of .8. The antibody of claim 5 , wherein the antibody is coupled to a composition selected from the group consisting of detectable substances and therapeutic ...

Подробнее
Номер записи: 1
19-07-2012 дата публикации

KIDNEY DISEASE TARGETS AND USES THEREOF

Номер: US20120183552A1
Автор: HE Tao, JOSELOFF Elizabeth, KIM Yeounjin, RUBEN Steve
Принадлежит: CELERA CORPORATION

The present invention provides a method for diagnosing and detecting diseases associated with kidney. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in kidney diseases (KCAT) and antibodies binds to KCATs. The present invention provides that KCATs are used as targets for screening agents that modulates the KCAT activities. Further the present invention provides methods for treating diseases associated with kidney. 1. An isolated protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-2736 and 5165-6044.2. A composition comprising the protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:2737-5164;b) nucleotide sequences that encode a protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-2736 and 5165-6044; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 , or transgenic organism that produces the antibody of .8. The antibody of claim 5 , wherein the antibody is coupled to a composition selected from the group consisting of detectable substances and therapeutic agents.9. A composition comprising the antibody of and a pharmaceutically acceptable carrier.10. An isolated antibody fragment of the antibody of claim 5 , wherein the antibody fragment comprises a fragment selected from the ...

Подробнее
Номер записи: 2
13-09-2012 дата публикации

ASSEMBLIES COMPRISING A POLYIMIDE FILM AND AN ELECTRODE, AND METHODS RELATING THERETO

Номер: US20120227790A1
Автор: Auman Brian C., Dunbar Meredith L., HE Tao, KOURTAKIS Kostantinos
Принадлежит: E. I DU PONT DE NEMOURS AND COMPANY

The assemblies of the present disclosure comprise an electrode, and a polyimide film. The polyimide film comprises a sub-micron filler and a polyimide. The polyimide is derived from at least one aromatic dianhydride component selected from rigid rod dianhydride, non-rigid rod dianhydride and combinations thereof, and at least one aromatic diamine component selected from rigid rod diamine, non-rigid rod diamine and combinations thereof. The mole ratio of dianhydride to diamine is 48-52:52-48 and the ratio of X:Y is 20-80:80-20 where X is the mole percent of rigid rod dianhydride and rigid rod diamine, and Y is the mole percent of non-rigid rod dianhydride and non-rigid rod diamine. The sub-micron filler is less than 550 nanometers in at least one dimension; has an aspect ratio greater than 3:1; is less than the thickness of the film in all dimensions. 1. An assembly comprising: [ i) at least one aromatic dianhydride component selected from the group consisting of: rigid rod dianhydride, non-rigid rod dianhydride and combinations thereof,', 'ii) at least one aromatic diamine component selected from the group consisting of: rigid rod diamine, non-rigid rod diamine and combinations thereof; and, 'a) a polyimide derived from, 'wherein the mole ratio of dianhydride to diamine is 48-52:52-48 and the ratio of X:Y is 20-80:80-20 where X is the mole percent of rigid rod dianhydride and rigid rod diamine, and Y is the mole percent of non-rigid rod dianhydride and non-rigid rod diamine based upon the total dianhydride component and total diamine component of the polyimide; and', i) being less than 550 nanometers (as a numerical average) in at least one dimension;', 'ii) having an aspect ratio greater than 3:1;', 'iii) being less than the polyimide film thickness in all dimensions;', 'iv) being present in an amount from 10 to 45 volume percent of the polyimide film; and, 'b) a sub-micron filler], 'A) a polyimide film having a thickness from 5 to 150 microns comprisingB) an ...

Подробнее
Номер записи: 3
13-09-2012 дата публикации

Thermally and dimensionally stable polyimide films and methods relating thereto

Номер: US20120231257A1
Автор: Brian C. Auman, Kostantinos Kourtakis, Meredith L. Dunbar, Tao He
Принадлежит: EI Du Pont de Nemours and Co

The present disclosure is directed to a polyimide film. The film is composed of a polyimide and a sub-micron filler. The polyimide is derived from at least one aromatic dianhydride component selected from rigid rod dianhydride, non-rigid rod dianhydride and combinations thereof, and at least one aromatic diamine component selected from rigid rod diamine, non-rigid rod diamine and combinations thereof. The mole ratio of dianhydride to diamine is 48-52:52-48 and the ratio of X:Y is 20-80:80-20 where X is the mole percent of rigid rod dianhydride and rigid rod diamine, and Y is the mole percent of non-rigid rod dianhydride and non-rigid rod diamine. The sub-micron filler is less than 550 nanometers in at least one dimension; has an aspect ratio greater than 3:1; is less than the thickness of the film in all dimensions.

Подробнее
Номер записи: 4
13-09-2012 дата публикации

Coverlay compositions and methods relating thereto

Номер: US20120231263A1
Автор: Brian C. Auman, Kostantinos Kourtakis, Meredith L. Dunbar, Tao He
Принадлежит: EI Du Pont de Nemours and Co

The present disclosure is directed to a coverlay comprising a polyimide film and an adhesive layer. The polyimide film is composed of a polyimide and a sub-micron filler. The polyimide is derived from at least one aromatic dianhydride component selected from rigid rod dianhydride, non-rigid rod dianhydride and combinations thereof, and at least one aromatic diamine component selected from rigid rod diamine, non-rigid rod diamine and combinations thereof. The mole ratio of dianhydride to diamine is 48-52:52-48 and the ratio of X:Y is 20-80:80-20 where X is the mole percent of rigid rod dianhydride and rigid rod diamine, and Y is the mole percent of non-rigid rod dianhydride and non-rigid rod diamine. The sub-micron filler is less than 550 nanometers in at least one dimension; has an aspect ratio greater than 3:1; is less than the thickness of the film in all dimensions.

Подробнее
Номер записи: 5
22-11-2012 дата публикации

INTERPOSER FILMS USEFUL IN SEMICONDUCTOR PACKAGING APPLICATIONS, AND METHODS RELATING THERETO

Номер: US20120292086A1
Автор: Auman Brian C., Dunbar Meredtih L., HE Tao, KOURTAKIS Kostantinos
Принадлежит: E. I. DU PONT DE NEMOURS AND COMPANY

An interposer film for IC packaging is disclosed. The interposer film comprises a substrate that supports a plurality of electrically conductive domains. The substrate is composed of a polyimide and a sub-micron filler. The polyimide is derived from at least one aromatic dianhydride component selected from rigid rod dianhydride, non-rigid rod dianhydride and combinations thereof, and at least one aromatic diamine component selected from rigid rod diamine, non-rigid rod diamine and combinations thereof. The mole ratio of dianhydride to diamine is 48-52:52-48 and the ratio of X:Y is 20-80:80-20 where X is the mole percent of rigid rod dianhydride and rigid rod diamine, and Y is the mole percent of non-rigid rod dianhydride and non-rigid rod diamine. The sub-micron filler is less than 550 nanometers in at least one dimension; has an aspect ratio greater than 3:1; is less than the thickness of the film in all dimensions. 1. An interposer film comprising a plurality of electrically conductive domains supported by a substrate having a thickness from 5 to 150 microns , the substrate comprises: i) at least one aromatic dianhydride component selected from the group consisting of rigid rod dianhydride, non-rigid rod dianhydride and combinations thereof, and', 'ii) at least one aromatic diamine component selected from the group consisting of rigid rod diamine, non-rigid rod diamine and combinations thereof;, 'a) a polyimide derived fromwherein the mole ratio of dianhydride to diamine is 48-52:52-48 and the ratio of X:Y is 20-80:80-20 where X is the mole percent of rigid rod dianhydride and rigid rod diamine, and Y is the mole percent of non-rigid rod dianhydride and non-rigid rod diamine based upon the total dianhydride component and total diamine component of the polyimide; and i) being less than 550 nanometers (as a numerical average) in at least one dimension;', 'ii) having an aspect ratio greater than 3:1;', 'iii) being less than the substrate thickness in all dimensions; ...

Подробнее
Номер записи: 6
28-02-2013 дата публикации

Connection mechanism capable of connecting housings

Номер: US20130051907A1
Автор: Guang-Yao Lee, He-Tao Han, Jun-Hua Tan, Song Deng, Wen-Kang Lo
Принадлежит: Hon Hai Precision Industry Co Ltd, Hongfujin Precision Industry Shenzhen Co Ltd

A connection mechanism to connect a first housing and a second housing together is provided. The connection mechanism includes a base, a button, and at least one rotatable member. The base includes at least one first hook and is slidably connected to the first housing. The base is capable of sliding between a first position where the first hook engages the second housing, and a second position where the first hook disengages from the second housing. The button is slidably connected to the first housing. The rotatable member is rotatably connected to the first housing, where one end of the rotatable member resists against the button, an opposite end of the rotatable member resists against the base, and the rotatable member is capable of being rotated about a shaft between the one end and the opposite end.

Подробнее
Номер записи: 7
14-03-2013 дата публикации

COLON CANCER TARGETS AND USES THEREOF

Номер: US20130067608A1
Автор: DOMON Bruno, HE Tao, LI Aiqun, MCCAFFERY Ian
Принадлежит: CELERA CORPORATION

The present invention provides a method for diagnosing and detecting diseases associated with colon. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in colon diseases (CCAT) and antibodies binds to CCAT. The present invention provides that CCAT is used as targets for screening agents that modulates the CCAT activities. Further the present invention provides methods for treating diseases associated with colon. 1. An isolated protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS: 1-683 and 1332-1501.2. A composition comprising the protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:684-1331;b) nucleotide sequences that encode a protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-683 and 1332-1501; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 , or transgenic organism that produces the antibody of .8. The antibody of claim 5 , wherein the antibody is coupled to a composition selected from the group consisting of detectable substances and therapeutic agents.9. A composition comprising the antibody of and a pharmaceutically acceptable carrier.10. An isolated antibody fragment of the antibody of claim 5 , wherein the antibody fragment comprises a fragment selected from the group ...

Подробнее
Номер записи: 8
21-03-2013 дата публикации

FIXING APPARATUS FOR HARD DISK DRIVE

Номер: US20130068907A1
Автор: DENG SONG, HAN HE-TAO, LEE GUANG-YAO, LO WEN-KANG, TAN JUN-HUA
Принадлежит:

A fixing apparatus for fixing a hard disk drive includes a bracket receiving the hard disk drive with a locating pin extending from each of opposite sidewalls, and a rotating member. The bracket includes two opposite supporting walls and an end wall. Each supporting wall defines a latching slot. The locating pins are slidably inserted into the corresponding latching slots. The rotating member includes a fixing pole slidably abutting against the hard disk drive toward the end wall, two rotating poles respectively extending from two opposite ends of the fixing pole and rotatably connected to the corresponding supporting walls, and a latching pole extending from a distal end of one of the rotating poles to be detachably latched to one of the supporting walls. 1. A fixing apparatus for a hard disk drive comprising a locating pin protruding from each of opposite sidewalls , the fixing apparatus comprising:a bracket for receiving the hard disk drive, the bracket comprising two opposite supporting walls for sandwiching the sidewalls, and an end wall connected between first ends of the supporting walls, each supporting wall defining a latching slot for slidably receiving a corresponding one of the locating pins; anda rotating assembly comprising a rotating member, the rotating member comprising a fixing pole slidably for abutting against a end of the hard disk drive toward the end wall, two rotating poles respectively extending out from two opposite ends of the fixing pole and rotatably and respectively connected to second ends of the supporting walls opposite to the end wall, and a latching pole extending from a distal end of one of the rotating pole opposite to the fixing pole and detachably latched to one of the supporting walls.2. The fixing apparatus of claim 1 , wherein the fixing pole is substantially U-shaped claim 1 , the rotating poles extend out from two opposite ends of the fixing pole away from each other claim 1 , the latching pole extends from the ...

Подробнее
Номер записи: 9
02-05-2013 дата публикации

COLON DISEASE TARGETS AND USES THEREOF

Номер: US20130111613A1
Автор: HE Tao, KIM Yeounjin, RUBEN Steve
Принадлежит: CELERA CORPORATION

The present invention provides a method for diagnosing and detecting diseases associated with colon. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in colon diseases (CCAT) and antibodies binds to CCAT. The present invention provides that CCAT is used as targets for screening agents that modulates the CCAT activities. Further the present invention provides methods for treating diseases associated with colon. 1. An isolated protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-1233 and 2228-2638.2. A composition comprising the protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:1234-2227;b) nucleotide sequences that encode a protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-1233 and 2228-2638; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 , or transgenic organism that produces the antibody of .8. The antibody of claim 5 , wherein the antibody is coupled to a composition selected from the group consisting of detectable substances and therapeutic agents.9. A composition comprising the antibody of and a pharmaceutically acceptable carrier.10. An isolated antibody fragment of the antibody of claim 5 , wherein the antibody fragment comprises a fragment selected from the group ...

Подробнее
Номер записи: 10
11-07-2013 дата публикации

METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING DISEASES

Номер: US20130177566A1
Автор: BIRSE Charles, DOMON Bruno, HE Tao, JOSELOFF Elizabeth, LEE Candy, MCKINNON Katherine, MESRI Mehdi, MOORE Paul, RUBEN Steve, VAN ORDEN Karen
Принадлежит: CELERA CORPORATION

Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro. 1. An isolated CAT protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-4 , 9 , 11-12 , 16-19 , 24-36 , 51-59 , 69-74 , 81-85 , 91-102 , 115-116 , 119-121 , 127-134 , 144-145 , 148-149 , 152-159 , 168-174 , and 182-183.2. A composition comprising the CAT protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:5-8, 10, 13-15, 20-23, 37-50, 60-68, 75-80, 86-90, 103-114, 117-118, 122-126, 135-143, 146-147, 150-151, 160-167, 175-181, 184-185;b) nucleotide sequences that encode a CAT protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-4, 9, 11-12, 16-19, 24-36, 51-59, 69-74, 81-85, 91-102, 115-116, 119-121, 127-134, 144-145, 148-149, 152-159, 168-174, and 182-183; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the CAT protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 , or transgenic organism that produces the antibody of .8. The antibody of claim 5 , wherein the antibody is coupled to a composition selected from the group consisting of detectable substances and therapeutic ...

Подробнее
Номер записи: 11
22-08-2013 дата публикации

Communication method, user equipment and base station

Номер: US20130215874A1
Автор: Dongli Yang, Tao He
Принадлежит: Huawei Technologies Co Ltd

Embodiments of the present disclosure provide a communication method, a base station and a user equipment. The communication method includes: sending, by a base station, a random access response message to a user equipment UE, where the random access response message includes a timing advance command, and a value T A of the timing advance command is N TA /(N*Ts), where, the N TA indicates the amount of the time alignment the UE, the N*Ts indicates a unit granularity for the UE to perform time alignment, the N is greater than 16, and the Ts indicates the smallest time unit. In the present disclosure, the unit granularity for the UE to perform time alignment may be enlarged, so that the UE can use a larger amount of the time alignment when performing the time alignment, thereby supporting the coverage of a cell with a long distance.

Подробнее
Номер записи: 12
28-11-2013 дата публикации

METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING DISEASES

Номер: US20130315915A1
Автор: HE Tao, LEE Candy, MOORE Paul, RUBEN Steve, VAN ORDEN Karen
Принадлежит: CELERA CORPORATION

Methods and compositions are provided for assessing, treating, and preventing diseases, especially cancer, using cancer-associated targets (CAT). Methods and compositions are also provided for determining or predicting the effectiveness of a treatment for these diseases or for selecting a treatment, using CAT. Methods and compositions are further provided for modulating cell function using CAT. Also provided are compositions that modulate CAT (e.g., antagonists or agonists), such as antibodies, proteins, small molecule compounds, and nucleic acid agents (e.g., RNAi and antisense agents), as well as pharmaceutical compositions thereof. Further provided are methods of screening for agents that modulate CAT, and agents identified by these screening methods. 1. An isolated protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-3 , 7-9 , 13-17 , 23 , 25-33 , 43-44 , 47-48 , 51-52 , 56-59 , 64-67 , and 72-73.2. A composition comprising the protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:4-6, 10-12, 18-22, 24, 34-42, 45-46, 49-50, 53-55, 60-63, 68-71, and 74-75;b) nucleotide sequences that encode a protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-3, 7-9, 13-17, 23, 25-33, 43-44, 47-48, 51-52, 56-59, 64-67, and 72-73; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 ...

Подробнее
Номер записи: 13
06-02-2014 дата публикации

ELECTRONIC DEVICES CONTAINING SWITCHABLY CONDUCTIVE SILICON OXIDES AS A SWITCHING ELEMENT AND METHODS FOR PRODUCTION AND USE THEREOF

Номер: US20140036576A1
Автор: HE Tao, Natelson Douglas, Tour James M., Yao Jun, Zhong Lin
Принадлежит: William Marsh Rice University

In various embodiments, electronic devices containing switchably conductive silicon oxide as a switching element are described herein. The electronic devices are two-terminal devices containing a first electrical contact and a second electrical contact in which at least one of the first electrical contact or the second electrical contact is deposed on a substrate to define a gap region therebetween. A switching layer containing a switchably conductive silicon oxide resides in the gap region between the first electrical contact and the second electrical contact. The electronic devices exhibit hysteretic current versus voltage properties, enabling their use in switching and memory applications. Methods for configuring, operating and constructing the electronic devices are also presented herein. 1. A method for operating an electronic device , said method comprising: a first electrical contact and second electrical contact, wherein the first electrical contact and the second electrical contact are arranged so as to define a gap region therebetween,', 'a substrate, wherein at least the first electrical contact is deposed on the substrate, and', 'a switching layer comprising a silicon oxide residing in the gap region; and, 'a) providing an electronic device comprisingb) applying an activating voltage to the electronic device to convert the silicon oxide into a switchably conductive state, wherein the activating voltage comprises an electroforming process.2. The method of claim 1 , wherein the switching layer comprises at least one vertical edge extending between the first electrical contact and the second electrical contact.3. The method of claim 1 , wherein the activating voltage forms a silicon nanocrystal switchably conductive pathway in the silicon oxide between the first electrical contact and the second electrical contact.4. The method of claim 1 , further comprising:c) applying a first programming voltage to the electronic device to set the electronic device to a ...

Подробнее
Номер записи: 14
05-01-2017 дата публикации

Method for Image Display and Display System

Номер: US20170004755A1
Автор: Jhen-Wei He, Lei Sun, Tao He
Принадлежит: Shenzhen China Star Optoelectronics Technology Co Ltd

A method for image display is provided. The method includes: providing a data signal of an image, and the data signal comprising grayscale values R, G, and B; obtaining brightness values LR, LG, and LB which the grayscale values R, G, and B correspond to; transforming the brightness values LR, LG, and LB into brightness values LR′, LG′, and LB′; obtaining grayscale values R′, G′, and B′ which the brightness values LR′, LG′, and LB′ correspond to; obtaining a minimum value among the grayscale values R, G, and B as a white grayscale value W′; and supplying the red subpixel, the green subpixel, the blue subpixel, and the white subpixel with the grayscale value R′, G′, B′, and white grayscale value W′, respectively so that the image can be shown on the display panel. The present invention also proposes a display system utilizing the method.

Подробнее
Номер записи: 15
21-01-2021 дата публикации

COLON DISEASE TARGETS AND USES THEREOF

Номер: US20210017259A1
Автор: HE Tao, KIM Yeounjin, RUBEN Steve
Принадлежит: CELERA CORPORATION

The present invention provides a method for diagnosing and detecting diseases associated with colon. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in colon diseases (CCAT) and antibodies binds to CCAT. The present invention provides that CCAT is used as targets for screening agents that modulates the CCAT activities. Further the present invention provides methods for treating diseases associated with colon. 1. An isolated protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-1233 and 2228-2638.2. A composition comprising the protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:1234-2227;b) nucleotide sequences that encode a protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-1233 and 2228-2638; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 , or transgenic organism that produces the antibody of .8. The antibody of claim 5 , wherein the antibody is coupled to a composition selected from the group consisting of detectable substances and therapeutic agents.9. A composition comprising the antibody of and a pharmaceutically acceptable carrier.10. An isolated antibody fragment of the antibody of claim 5 , wherein the antibody fragment comprises a fragment selected from the group ...

Подробнее
Номер записи: 16
23-01-2020 дата публикации

Vehicle running board apparatus and retractable device thereof

Номер: US20200023780A1
Автор: Qi Zhang, Songfeng Wang, Tao He, Xinfa Du, Xing Fan, Yiming Wang, Yongyong ZHAN
Принадлежит: T Max Hangzhou Technology Co Ltd

The present disclosure relate to a vehicle running board apparatus and a retractable device thereof. In some embodiments, a retractable device includes a running board holder and an arm assembly. The running board holder has a connecting portion, and the arm assembly is configured to drive the running board holder to move between an extended position and a retracted position. The arm assembly includes a first arm and a second arm. The first arm has a first end and a second end. The second end of the first arm is pivotally connected to the connecting portion of the running board holder. The second arm has a first end and a second end. The second end of the second arm is pivotally connected to the connecting portion of the running board holder. The second end of at least one of the first arm or the second arm straddles the connecting portion.

Подробнее
Номер записи: 17
31-01-2019 дата публикации

CAPPED AND UNCAPPED ANTIBODY CYSTEINES, AND THEIR USE IN ANTIBODY-DRUG CONJUGATION

Номер: US20190030183A1
Автор: HE Tao, Kriz Ronald William, Letendre Leo Joseph, Prashad Amarnauth Shastrie, Somers Will, Wang Wenge, Zhong Xiaotian
Принадлежит: PFIZER INC.

An antibody production process in mammalian cells in which engineered unpaired cysteine residues are post-translationally modified and capped with particular chemical entities, which capped antibodies are well suited to further site-specific conjugation steps to form antibody-drug conjugates (ADCs) or protein drug conjugates; ADCs produced using these capped antibodies including in particular ADCs formed by the selective reduction of the capped antibodies' cysteine residues, and ADCs formed using chemical handles such as aldehyde/azide/alkyne biorthogonal groups, which permit additional drug conjugation chemistry; and uncapped antibodies produced by cells in low cysteine, cysteine and glutathione media, and ADCs produced via direct conjugation to these uncapped antibodies. 1. A method of bonding a predetermined capping moiety onto one or more unpaired cysteine residues on an antibody , said method comprising the step of: growing an antibody-expressing cell line in a culture medium containing said predetermined capping moiety , or a precursor of said predetermined capping moiety , wherein said cell line expresses said antibody , and wherein said predetermined capping moiety is attached by a covalent bond to at least one of said unpaired cysteine residues on said expressed antibody.2. The method of claim 1 , wherein said predetermined capping moiety is selected from the group consisting of 5-thio-2-nitrobenzoic acid (TNB) claim 1 , 2-mercaptopyridine claim 1 , dithiodipyridine (DTDP) claim 1 , 4-thiobenzoic acid claim 1 , 2-thiobenzoic acid claim 1 , 4-thiobenzenesulfonic acid claim 1 , 2-thiobenzenesulfonic acid claim 1 , methyl sulfonate (Ms) claim 1 , p-toluenesulfonate (Ts) and trifluoromethanesulfonate (Tf).3. The method of claim 1 , wherein said predetermined capping moiety is selected from a reactive group consisting of maleimido trioxa-4-formyl benzamide (MTFB) like molecules with an aldehyde handle or maleimido azido-lysine like molecules with an azide handle ...

Подробнее
Номер записи: 18
17-02-2022 дата публикации

Rotating cored-type biological treatment device of low-carbon-source wastewater and usage method therefor

Номер: US20220048799A1
Автор: Ming KONG, Tao He, Xueting XU, Yimin Zhang, Yueming Zhu, Yuexiang GAO, Zhihao Li
Принадлежит: Nanjing Institute of Environmental Sciences MEE, Nanjing Institute Of Environmental Sciences Ministry Of Ecology And Enviroment Of People's

Disclosed is a rotating cored-type biological treatment device for wastewater with low carbon content and use thereof. The device includes a composite frame ( 1 ), several biological packing columns ( 2 ), a rotating tray ( 3 ), a rotating shaft, and a base ( 4 ), wherein the biological packing columns ( 2 ) are detachably mounted inside the composite frame ( 1 ); the rotating shaft is vertically arranged on the base ( 4 ) and can rotate; the rotating tray ( 3 ) is fixedly sheathed on the rotating shaft, and the composite frame ( 1 ) is disposed on the rotating tray ( 3 ); and the rotating tray rotates with the rotating shaft, which driving the composite frame ( 1 ) and the biological packing columns ( 2 ) therein to rotate. The rotating cored-type biological treatment device has the advantages of high efficiency and being renewable and environment-friendly, etc.

Подробнее
Номер записи: 19
03-03-2022 дата публикации

METHOD AND DEVICE FOR GENERATING COLLECTION OF INCORRECTLY-ANSWERED QUESTIONS

Номер: US20220067416A1
Автор: CHEN Mingquan, HE Tao, LUO Huan, MAO Lihui
Принадлежит: Hangzhou Dana Technology Inc.

A method and a device for generating a collection of incorrectly-answered questions are provided. The method includes: acquiring an image of a marked test paper (S); recognizing regions of respective questions in the marked test paper according to a pre-trained first region recognition model (S); recognizing a question whose marking result is incorrect in the marked test paper as an incorrectly-answered question according to a pre-trained incorrectly-answered question recognition model (S); and storing the region of the incorrectly-answered question in an incorrectly-answered question database to generate the collection of incorrectly-answered questions (S). The above solution may solve the problem of low efficiency in generating the collection of incorrectly-answered questions in the prior art.

Подробнее
Номер записи: 20
25-02-2016 дата публикации

Method And System For Assessing A Health Condition

Номер: US20160055296A1
Автор: HE Tao, HUANG Shi, LI RUI, LIU JIQUAN, Xu Jian
Принадлежит:

The present invention relates to a method of assessing whether a subject mammal has a target condition, comprising a step of formulating a function of abundances of a first group of biomarkers and abundances of a second group of biomarkers that is useful for assessing whether the subject mammal has the target condition. The present invention also relates to a computer-aided system for assessing whether a subject mammal has a target condition. The present invention further relates to a computer-readable medium for assessing whether a subject mammal has a target condition 1. A method of assessing whether a subject mammal has a target condition , comprising the steps:a) defining the target condition;b) defining a first group of biomarkers each having a higher abundance in oral cavities of a set of test mammals with said target condition compared to oral cavities of a set of test mammals without said target condition;c) defining a second group of biomarkers each having a lower abundance in the oral cavities of the set of test mammals with said target condition compared to the oral cavities of the set of test mammals without said target condition;d) formulating a function of the abundances of the first group of biomarkers and the abundances of the second group of biomarkers that is useful for assessing whether the subject mammal has the target condition;e) obtaining a sample from an oral cavity of the subject mammal, wherein the obtained sample is capable of containing the first group of biomarkers and the second group of biomarkers;f) measuring abundances of the first group of biomarkers in the obtained sample from the subject mammal;g) measuring abundances of the second group of biomarkers in the obtained sample from the subject mammal; andh) inputting the measured abundances of the first group and the second group of biomarkers into the formulated function to assess whether the subject mammal has the target condition.2. The method according to claim 1 , wherein the ...

Подробнее
Номер записи: 21
14-02-2019 дата публикации

METHOD AND APPARATUS FOR GENERATING TRAINING DATA FOR HUMAN FACE RECOGNITION, DEVICE AND COMPUTER STORAGE MEDIUM

Номер: US20190050632A1
Автор: HE Tao, LIU Jingtuo, LIU Wenxian, WENG Renliang, Zhang Gang
Принадлежит: BAIDU ONLINE NETWORK TECHNOLOGY (BEIJING) CO., LTD .

The present disclosure provides a method and apparatus for generating training data for human face recognition, a device and a computer storage medium, wherein the method comprises: inputting accessory-not-worn face images into a generative network, to obtain accessory-worn face images; using the accessory-worn face images as second training data for building the human face recognition model; wherein the generative network is a generative network in a generative adversarial network obtained by pre-training with first training data, the first training data including the accessory-not-worn face images and accessory-worn face images corresponding to a same user identifier. In the present disclosure, the accessory-worn face images obtained in a data augmentation manner greatly expand the amount of training data for building the human face recognition model, and thereby improve the recognition accuracy of the accessory-worn face images. 1. A method of generating training data for human face recognition , wherein the method comprises:inputting accessory-not-worn face images into a generative network, to obtain accessory-worn face images;using the accessory-worn face images as second training data for building the human face recognition model;wherein the generative network is a generative network in a generative adversarial network obtained by pre-training with first training data, the first training data including the accessory-not-worn face images and accessory-worn face images corresponding to a same user identifier.2. The method according to claim 1 , wherein the accessory comprises glasses claim 1 , a mask or a cap.3. The method according to claim 1 , wherein pre-training the generative adversarial network comprises:obtaining first training data which include the accessory-not-worn face images and accessory-worn face images corresponding to the same user identifier;training the generative adversarial network by regarding the accessory-not-worn face images and ...

Подробнее
Номер записи: 22
02-03-2017 дата публикации

Fluorscent Probes To Assess Stannous Containing Oral Care Products

Номер: US20170056531A1
Автор: Barker Matthew Lloyd, Chang Jinlan, Dong Weili, HE Tao, He Yanyan, JR. Donald James, Shi Yunming, Strand Ross, White
Принадлежит:

A method of quantitating sorption of stannous by microbial cells of a biofilm is an effective way of assessing efficacy of oral care products containing stannous. 1. A method of quantitating sorption of stannous by microbial cells of a biofilm comprising the steps:a. treating the biofilm with a stannous containing oral care product;b. labeling the biofilm with a microbial fluorescent probe;c. labeling the biofilm with a stannous fluorescent probe; andd. quantitating the labeled cells by measuring fluorescence light emitted from the labeled cells.2. The method of claim 1 , wherein the step of quantitating the labeled cells by measuring fluorescence light emitted from the labeled cells is by confocal laser scanning microscopy (CLSM).3. The method of claim 1 , wherein the steps of labeling the biofilm with the microbial fluorescent probe and the stannous fluorescent probe are before the step of treating the biofilm with the stannous containing oral care product.4. The method of claim 1 , wherein the biofilm is an in situ plaque biofilm.5. The method of claim 4 , wherein treating the in situ plaque biofilm with the stannous containing oral care product is treated in vivo.6. The method of claim 4 , wherein treating the in situ plaque biofilm with the stannous containing oral care product is treated ex vivo.7. The method of claim 1 , further comprising the step of having human subjects wear an oral appliance for 6 hours to 4 days wherein at least a portion of the oral appliance comprises hydroxylapatite (HA) as a surface of the biofilm.8. The method of claim 1 , further comprising the step of having human subjects wear an oral appliance for 1-3 days wherein at least a portion of the oral appliance comprises hydroxylapatite (HA) as a surface of the biofilm wherein the HA is on the buccal side of the oral appliance.9. The method of claim 7 , wherein the biofilm is an in situ plaque biofilm.10. The method of claim 7 , wherein the HA surface of the biofilm is treated with the ...

Подробнее
Номер записи: 23
20-02-2020 дата публикации

Anti-gdf15 antibodies, compositions and methods of use

Номер: US20200055930A1
Автор: Danna M. BREEN, James R. APGAR, Jeffrey Raymond Chabot, Kevin Charles BEAUMONT, Ksenya SHCHORS, Matthew Allister Lambert, Tao He
Принадлежит: PFIZER INC

The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to GDF15, as well as methods and uses for the antibodies.

Подробнее
Номер записи: 24
08-03-2018 дата публикации

SYSTEMS AND METHODS FOR CONTROLLING AN X-RAY TUBE FILAMENT

Номер: US20180064410A1
Автор: HE Tao, JIANG Yifeng, Li Hua, YANG Yong, Zhou Jiawen
Принадлежит: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.

This application disclosures a method for calibrating filament current data of an X-ray tube. The method includes obtaining a first value of tube current to be calibrated and a value of filament current to be calibrated, the tube current to be calibrated and the filament current to be calibrated corresponding to a first calibration point; performing an emission operation based on the first value of the tube current to be calibrated and the value of the filament current to be calibrated; determining an actual value of the tube current during the emission operation; determining a difference between the actual value of the tube current and the first value of the tube current to be calibrated; and calibrating, based on the difference, the first calibration point. 1. A method for calibrating filament current data of an X-ray tube , comprising:obtaining a first value of tube current to be calibrated and a value of filament current to be calibrated, the tube current to be calibrated and the filament current to be calibrated corresponding to a first calibration point;performing an emission operation based on the first value of the tube current to be calibrated and the value of the filament current to be calibrated;determining an actual value of the tube current during the emission operation;determining a difference between the actual value of the tube current and the first value of the tube current to be calibrated; andcalibrating, based on the difference, the first calibration point.2. The method of claim 1 , wherein calibrating claim 1 , based on the difference claim 1 , the first calibration point comprises:determining whether the difference is satisfied with a preset condition; andgenerating, if the difference is satisfied with the preset condition, filament current calibration data corresponding to the first calibration point.3. The method of claim 2 , wherein determining whether the difference is satisfied with the preset condition comprises determining whether the ...

Подробнее
Номер записи: 25
28-02-2019 дата публикации

METHOD AND APPARATUS FOR BUILDING HUMAN FACE RECOGNITION MODEL, DEVICE AND COMPUTER STORAGE MEDIUM

Номер: US20190065906A1
Автор: HE Tao, LIU Jingtuo, LIU Wenxian, WENG Renliang, Zhang Gang
Принадлежит: BAIDU ONLINE NETWORK TECHNOLOGY (BEIJING) CO., LTD .

The present disclosure provides a method and apparatus for building a human face recognition model, a device and a computer storage medium, wherein the method comprises: regarding a known user's face images annotated with ages as training samples; using the training samples to train a deep neural network to obtain a human face recognition model, the human face recognition model being used to perform user identification for input face images. The present disclosure can solve the problem about reduction of the face recognition rate caused by age changes, and improve robustness of face recognition for ages. 1. A method of building a human face recognition model , wherein the method comprises:regarding a known user's face images annotated with ages as training samples;using the training samples to train a deep neural network to obtain a human face recognition model, the human face recognition model being used to perform user identification for input face images.2. The method according to claim 1 , wherein the deep neural network comprises: a convolutional neural network or a residual convolutional neural network.3. The method according to claim 1 , wherein a training target upon training the deep neural network is:to minimize similarity between face images of different persons, and the similarity between face images of the same person at different ages is negatively correlated to an age difference.4. The method according to claim 3 , wherein the using the training samples to train a deep neural network to obtain a human face recognition model comprises:using the deep neural network to learn the training samples to obtain face features of respective training samples;using face features of the respective training samples to determine a recognition loss, and using the recognition loss to perform parameter adjustment for the deep neural network to minimize the recognition loss;wherein the recognition loss is determined by similarity between face images of different persons ...

Подробнее
Номер записи: 26
07-03-2019 дата публикации

Distance Measurement and tracking positioning apparatus and method formobile device

Номер: US20190072660A1
Автор: Gangzhi He, Jianfei Zhang, Lei Zhao, Liyuan LIU, Qiang Wang, Tao He, Wenlong Liao
Принадлежит: Cowa Robotic Co Ltd

The present invention provides an apparatus and a method for ranging, following and positioning of a mobile device. The apparatus includes an emitting unit, a receiving unit, and a computing unit. The emitting unit and the receiving unit are connected to the computing unit. The emitting unit is configured to emit a centimeter wave to an object to be followed. The receiving unit is configured to receive the centimeter wave. The computing unit is configured to calculate a distance between the mobile device and the object to be followed according to a time difference between emission of the centimeter wave and reception of the centimeter wave, and further calculate a movement distance according to the distance and a threshold distance difference. The present invention can be made waterproof and oil resistant. Compared with the technology using laser, the present invention better prevents measurement failure caused by permeability of the medium.

Подробнее
Номер записи: 27
18-03-2021 дата публикации

CALCULATION PRACTICING METHOD, SYSTEM, ELECTRONIC DEVICE AND COMPUTER READABLE STORAGE MEDIUM

Номер: US20210082301A1
Автор: CHEN Mingquan, HE Tao, LUO Huan
Принадлежит: Hangzhou Dana Technology Inc.

The disclosure provides a calculation practicing method, a system, an electronic device and a computer readable storage medium, the calculation practicing method includes: providing a calculation question; identifying the type and content of the calculation question; generating an answer area according to the type and content of the calculation question; receiving an answering operation in which the user inputs the answer string for the calculation question in the answer area; identifying the answer string inputted by the user; and determining whether each of the answer characters in the answer string is correct, if there is an incorrect answer character, it will be marked, so that the calculation practice can be realized through the electronic device, which is convenient for students to carry out training. 1. A calculation practicing method , the calculation practicing method comprising:providing a calculation question;identifying the type and the content of the calculation question;generating an answer area according to the type and the content of the calculation question;receiving an answering operation in which a user inputs an answer string for the calculation question in the answer area;identifying the answer string inputted by the user; anddetermining whether each answer character in the answer string is correct, and if there is an incorrect answer character, marking the incorrect answer character.2. The calculation practicing method according to claim 1 , wherein if there is the incorrect answer character claim 1 , a correct answer character is also displayed when marking the incorrect answer character.3. The calculation practicing method according to claim 1 , wherein after identifying the type of the calculation question claim 1 , the calculation practicing method further comprises:determining whether it is necessary to generate a vertical calculation formula according to the type and the content of the calculation question, and if the vertical calculation ...

Подробнее
Номер записи: 28
14-03-2019 дата публикации

METHOD AND APPARATUS FOR GENERATING IMAGE

Номер: US20190080148A1
Автор: HE Tao, LIU Jingtuo, Zhang Gang
Принадлежит:

The present disclosure discloses a method and apparatus for generating an image. A specific embodiment of the method comprises: acquiring at least two frames of facial images extracted from a target video; and inputting the at least two frames of facial images into a pre-trained generative model to generate a single facial image. The generative model updates a model parameter using a loss function in a training process, and the loss function is determined based on a probability of the single facial generative image being a real facial image and a similarity between the single facial generative image and a standard facial image. According to this embodiment, authenticity of the single facial image generated by the generative model may be enhanced, and then a quality of a facial image obtained based on the video is improved. 1. A method for generating an image , comprising:acquiring at least two frames of facial images extracted from a target video; and inputting a single facial generative image outputted by an initial generative model into a pre-trained discriminative model to generate a probability of the single facial generative image being a real facial image;', 'determining a loss function of the initial generative model based on the probability and a similarity between the single facial generative image and a standard facial image, the standard facial image and the single facial generative image containing facial information of a same person; and', 'updating a model parameter of the initial generative model using the loss function to obtain the generative model,', 'wherein the method is performed by at least one processor., 'inputting the at least two frames of facial images into a pre-trained generative model to generate a single facial image, wherein the generative model is obtained through2. The method according to claim 1 , wherein the determining a loss function of the initial generative model comprises:extracting respectively feature information of the ...

Подробнее
Номер записи: 29
14-03-2019 дата публикации

METHOD AND APPARATUS FOR GENERATING IMAGE

Номер: US20190080433A1
Автор: HE Tao, LIU Jingtuo, Zhang Gang
Принадлежит:

A method and an apparatus for generating an image are provided. A specific embodiment of the method comprises: acquiring a to-be-processed facial image, the image resolution of the to-be-processed facial image being lower than a preset first resolution threshold; and inputting the to-be-processed facial image into a pre-trained generativemodel to generate a processed facial image. The generative model updates a model parameter using a loss function in a training process, and the loss function is determined based on a probability of an image group being positive sample data, the image group composed of a facial sample image and a facial generative image. According to this embodiment, authenticity of the generated facial image is enhanced. 1. A method for generating an image , comprising:acquiring a to-be-processed facial image, an image resolution of the to-be-processed facial image being lower than a preset first resolution threshold; andinputting the to-be-processed facial image into a pre-trained generative model to generate a processed facial image, wherein the generative model is obtained through the following training:inputting a facial sample image into an initial generative model, and outputting, by the initial generative model, a facial generative image, an image resolution of the facial sample image being lower than the first resolution threshold;inputting a 2-tuple composed of a pixel matrix of the facial sample image and a pixel matrix of the facial generative image into a pre-trained discriminative model, and outputting, by the discriminative model, a probability of an image group being positive sample data, the image group composed of the facial sample image and the facial generative image, and the positive sample data comprising a first real facial image whose image resolution higher than a second resolution threshold and a second real facial image whose image resolution lower than the first resolution threshold which is generated based on the first ...

Подробнее
Номер записи: 30
31-03-2022 дата публикации

Examination paper correction method and apparatus, electronic device, and storage medium

Номер: US20220101030A1
Автор: Huan LUO, Lihui Mao, Mingquan CHEN, Tao He
Принадлежит: Hangzhou Dana Technology Inc

An examination paper correction method and apparatus, an electronic device, and a storage medium are provided. The method includes: obtaining a first image of a standard examination paper; identifying an area and characters of each standard answer in the first image, and using a marking box to mark an answering area where each standard answer is located; determining position information of each marking box; obtaining a second image of an examination paper to be corrected; determining, according to the position information of each marking box of the first image, an answering area in the second image matching a position of the marking box , and using a marking box to mark the determined answering area; identifying characters of an answer to be corrected in each marking box of the second image; and comparing the characters of the standard answer with the characters of the answer to be corrected.

Подробнее
Номер записи: 31
23-03-2017 дата публикации

ELECTRONIC DEVICE ENCLOSURE

Номер: US20170086326A1
Автор: CHAI CHUNG, HAN HE-TAO, JING XIAO-ZHONG, LIN YI-SHENG, Peng Yong, TAN JUN-HUA, WANG Liang-Chin
Принадлежит:

An electronic device enclosure includes a chassis, a bracket, a shaft and a supporting member. The bracket is rotatably connected to the chassis through the shaft. The supporting member is sheathed with the shaft. Two opposite ends of the supporting member are respectively fixed to the chassis and the bracket. When the bracket rotates in a first direction relative to the chassis, the supporting member is elastically deformable to support the bracket preventing the bracket from rotating towards a second direction relative to the chassis. And the first direction is opposite to the second direction. 1. An electronic device enclosure comprising:a chassis;a bracket connected to the chassis;a shaft configured to rotatably connect the chassis to the bracket; anda supporting member sheathed with the shaft and having opposite ends of the supporting member are respectively fixed to the chassis and the bracket;wherein when the bracket is rotated relative to the chassis in a first direction, and the supporting member is elastically deformed to support the bracket to prevent the bracket from rotating towards a second direction opposite to the first direction.2. The electronic device enclosure of claim 1 , wherein the supporting member is an elastic element claim 1 , and the elastic element is a spring.3. The electronic device enclosure of claim 2 , wherein the chassis defines a first gap claim 2 , the bracket defines a second gap claim 2 , and opposite ends of the spring are engaged in the first gap and the second gap.4. The electronic device enclosure of claim 1 , further comprising a rotary member and a mounting member fixed to the bracket claim 1 , wherein the mounting member defines a groove claim 1 , and the rotary member is received in the groove.5. The electronic device enclosure of claim 4 , wherein the groove comprises a plurality of protrusions claim 4 , a notch is formed by the two adjacent protrusions claim 4 , the rotary member is received in the notch and is ...

Подробнее
Номер записи: 32
19-03-2020 дата публикации

METHOD AND SYSTEM FOR INTELLIGENT IDENTIFICATION AND CORRECTION OF QUESTIONS

Номер: US20200090539A1
Автор: CHEN Mingquan, HE Tao, LUO Huan
Принадлежит: Hangzhou Dana Technology Inc.

A method and a system for intelligent identification and correction of a question, which implements, through artificial intelligence, automatic identification of stems of various types of questions and contents of answering in test papers and auto-corrects the contents of answering. The technical solution is: to train a neural network model (e.g., CNN model) into a model for question type recognition based on numerous test paper samples in advance, and to use this trained model to detect the position of individual questions, the type corresponding to the question, the different components of the question (stem, answer, picture) in the test paper, and then to identify the printed font character information of the stem and the handwriting font character information of the answer part based on the recognition model, and finally to auto-correct based on the identified character information. 1. A method for intelligent identification of a question , comprising:{'b': '1', 'Step : identifying regions of individual questions on a test paper based on an image of the test paper and a first model trained in advance, wherein the first model is a neural network based model;'}{'b': '2', 'Step : identifying question type for regions of the individual questions respectively by using the first model, and labeling the identified individual types of questions respectively, and labeling individual components of the corresponding type of the question in the region of individual questions, the components including stems, answers, and/or pictures; and'}{'b': '3', 'Step : identifying characters in the region of the individual questions based on the separate images of the regions of the individual questions on the test paper, the type of the question corresponding to the region of the question, the component corresponding to the region of the question, and a second model, so as to determine the information recorded on the test paper, wherein the second model is a neural network based model ...

Подробнее
Номер записи: 33
26-06-2014 дата публикации

Colon disease targets and uses thereof

Номер: US20140178391A1
Автор: Aiqun Li, Bruno Domon, Ian MCCAFFREY, Tao He
Принадлежит: Celera Corp

The present invention provides a method for diagnosing and detecting diseases associated with colon. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in colon diseases (CCAT) and antibodies binds to CCAT. The present invention provides that CCAT is used as targets for screening agents that modulates the CCAT activities. Further the present invention provides methods for treating diseases associated with colon.

Подробнее
Номер записи: 34
12-05-2022 дата публикации

Nano-wall Integrated Circuit Structure with High Integrated Density

Номер: US20220149198A1
Автор: Feng Ke, HE Tao, HU Zhaoxi, LI PING, LI Yaosen, LIAO Yongbo, Lin Fan, PENG Chenxi, XIONG Xuanlin, ZENG Xianghe
Принадлежит:

A nano-wall integrated circuit structure with high integration density is disclosed, which relates to the fields of microelectronic technology and integrated circuits (IC). Based on the different device physical principles with MOSFETs in traditional ICs, the nano-wall integrated circuit unit structure (Nano-Wall FET, referred to as NWaFET) with high integration density can improve the integration of the IC, significantly shorten the channel length, improve the flexibility of the device channel width-to-length ratio adjustment, and save chip area. 1. A nano-wall integrated circuit structure (NWaFET) , comprising:a well semiconductor region having a first conductivity type,a heavily doped drain region on the well semiconductor region, wherein the heavily doped drain region has a second conductivity type and includes an upper portion and a lower portion, and the lower portion is wider than the upper portion and has bottom and side surfaces surrounded by the well semiconductor region,a lightly doped drain region above the heavily doped drain region, the lightly doped drain region having the second conductivity type;a heavily doped, first conductivity type channel semiconductor region above the lightly doped drain region;a heavily doped, second conductivity type source region above the channel semiconductor region, wherein the heavily doped source region comprises a narrow bandgap pseudocrystalline, narrow bandgap polycrystalline or single crystal silicon semiconductor;an insulating gate dielectric and a gate electrode on a first side surface of each of the upper portion of the heavily doped drain region, the lightly doped drain region, the channel semiconductor region, and the heavily doped source region; andan insulating material on a second side surface of each of the heavily doped source region, the channel semiconductor region, the lightly doped drain region, and the upper portion of the heavily doped drain region, anda drain electrode in contact with the heavily ...

Подробнее
Номер записи: 35
29-04-2021 дата публикации

Method and Device for Simultaneously Measuring Mass Concentrations of Particulates with Different Sizes

Номер: US20210123847A1
Автор: HE Tao, Liu Zhiqiang, XIONG Youhui, Yang Wei
Принадлежит: Cubic Sensor and Instrument Co.,Ltd

The invention relates to a method and device for simultaneously measuring mass concentrations of particulates with different sizes. The method detects particulates within different size ranges in air based on laser scattering and can eliminate cross interference between the particulates within different size ranges. The device is simple in structure, can realize on-line simultaneous measurement of PM1.0, PM2.5 and PM10 with high measurement precision and low cost. 1. A method for simultaneously measuring mass concentrations of particulates with different sizes , comprising the following steps:S1: calculating a correction coefficient of the number of small-size particulates that are misjudged as large-size particulates; andS2: correcting a measured number of small-size particulates or a measured number and mass concentration of large-size particulates according to the correction coefficient;wherein the large-size particulates are particulates with sizes greater than a maximum size of the small-size particulates; andwherein calculating the correction coefficient of the number of the small-size particulates that are misjudged as the large-size particulates in Step S1 comprises the following steps:S11: collecting a measured air flow only containing small-size particulates, and detecting, by a multi-channel air quality detection device, the number of particulates with different sizes in the measured air flow to obtain the total number of the particulates with different sizes and the number of large-size particulates; andS12: dividing the number of the large-size particulates by the total number of the particulates with different sizes to obtain the correction coefficient of the number of the small-size particulates that are misjudged as the large-size particulates.2. The method according to claim 1 , wherein correcting the measured number of the small-size particulates according to the correction coefficient in Step S2 comprises the following steps:S13: detecting, by the ...

Подробнее
Номер записи: 36
10-07-2014 дата публикации

METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING DISEASES

Номер: US20140193419A1
Автор: BIRSE Charles, DOMON Bruno, HE Tao, JOSELOFF Elizabeth, LEE Candy, MCKINNON Katherine, MESRI Mehdi, MOORE Paul, RUBEN Steve, VAN ORDEN Karen
Принадлежит: CELERA CORPORATION

Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro. 1. An isolated CAT protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-4 , 9 , 11-12 , 16-19 , 24-36 , 51-59 , 69-74 , 81-85 , 91-102 , 115-116 , 119-121 , 127-134 , 144-145 , 148-149 , 152-159 , 168-174 , and 182-183.2. A composition comprising the CAT protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:5-8, 10, 13-15, 20-23, 37-50, 60-68, 75-80, 86-90, 103-114, 117-118, 122-126, 135-143, 146-147, 150-151, 160-167, 175-181, 184-185;b) nucleotide sequences that encode a CAT protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-4, 9, 11-12, 16-19, 24-36, 51-59, 69-74, 81-85, 91-102, 115-116, 119-121, 127-134, 144-145, 148-149, 152-159, 168-174, and 182-183; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the CAT protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 , or transgenic organism that produces the antibody of .8. The antibody of claim 5 , wherein the antibody is coupled to a composition selected from the group consisting of detectable substances and therapeutic ...

Подробнее
Номер записи: 37
11-04-2019 дата публикации

TOOL-LESS MOUNTING APPARATUS FOR HARD DISK DRIVE AND STORAGE DEVICE USING THE SAME

Номер: US20190108860A1
Автор: HAN HE-TAO, JING XIAO-ZHONG, LIN YI-SHENG, TAN JUN-HUA, WANG Liang-Chin
Принадлежит:

A hand-mountable mounting apparatus for hard disk drives (HDD) and storage devices using HDD includes a tray defining an installation space for the hard disk drive and a locking unit. The tray includes a hook. A bracket of the locking unit includes defines a first locking slot corresponding to the hook and a sliding plate defining a second locking slot corresponding to the hook and the first locking slot. The sliding plate is slidable between an unlock position, where the hook is free to withdraw, and a lock position, where the first locking slot and the second locking slot are not aligned and the hook is latched by the sliding plate. 1. A tool-less mounting apparatus for hard disk drive comprising:a tray defining an installation space for the hard disk drive and comprising a hook; and a supporting bracket defining a first locking slot corresponding to the hook; and', 'a sliding plate slidably connected to a side of the supporting bracket and defining a second locking slot corresponding to the hook and the first locking slot;, 'a locking unit comprisingwherein the hook is coupled to the sliding plate by passing through the first locking slot and the second locking slot; the sliding plate is slidable between an unlocking position, where the first locking slot aligns with the second locking slot and the hook is free to pass through the first locking slot and the second locking slot, and a locking position, where the first locking slot and the second locking slot are not aligned and the hook is stopped by the sliding plate.2. The mounting apparatus of claim 1 , wherein the mounting apparatus further comprises a resilient member connected between the sliding plate and the supporting bracket;when the sliding plate is forced to slide to the unlocking position, the resilient member is elastically deformed; when the sliding plate is unforced, the resilient member drives the sliding plate to slide to the locking position under restoring force.3. The mounting apparatus of ...

Подробнее
Номер записи: 38
09-04-2020 дата публикации

APPARATUS AND METHOD FOR REMOVING NITROGEN AND PHOSPHORUS FROM SEWAGE BY USING SPONGE IRON AND ACTIVATED SLUDGE

Номер: US20200109073A1
Автор: Chen Xi, HE Tao, JIANG WENTING, Liu Xiaowen, WEI DONGYANG, WEI Xiang, WU Yonggang, Zhou Wen, ZHU JIALIANG
Принадлежит:

An apparatus and a method for removing nitrogen and phosphorus from sewage by using sponge iron and activated sludge are disclosed herein. The apparatus comprises a raw tank, a pH adjusting tank, a primary SBBR reactor, a secondary SBBR reactor, an intermediate tank, and a discharge tank; by modification of sponge iron, preparation of composite filler, sludge inoculation and domestication, and sewage treatment, an effect of simultaneous denitrification and dephosphorization is achieved in one reactor using the combined action of sponge iron and activated sludge with high nitrogen and phosphorus removal efficiency. 1. An apparatus for removing nitrogen and phosphorus from sewage using sponge iron and activated sludge , comprisinga raw tank (1) for accommodating sewage,{'b': 2', '2', '21, 'a pH adjusting tank () connected to the raw tank () for adjusting the sewage to pH 6.5-7.5 and is provided at bottom with a first vent valve () for discharging sewage and sludge therein,'}{'b': 15', '2, 'a temperature adjustment device () inside the pH adjusting tank () for adjusting the temperature of the sewage to 28-32° C.,'}{'b': 3', '2, 'a primary SBBR reactor () connected to the pH adjusting tank () for accommodating a composite filler prepared from the sponge iron, acclimating the activated sludge and conducting primary treatment,'}{'b': 10', '3', '101, 'an intermediate tank () connected to the primary SBBR reactor () and is provided at bottom with a second vent valve () for emptying the sewage therein,'}{'b': 4', '10', '2, 'a secondary SBBR reactor () connected to the intermediate tank () and the pH adjusting tank (), respectively, for accommodating the composite filler prepared from the sponge iron, acclimating the activated sludge and conducting secondary treatment, and'}{'b': 11', '4', '111, 'a discharge tank () connected to the secondary SBBR reactor () and is provided at bottom with a third vent valve () for discharging sewage and sludge therein.'}2. The apparatus ...

Подробнее
Номер записи: 39
25-08-2022 дата публикации

METHOD FOR ALLOCATING RESOURCE AND ACCESSING IN OPEN WIRELESS CHANNELS

Номер: US20220272703A1
Автор: DONG Mingke, HE Tao, JIN Ye, LIU Aimin, LV Guocheng, WANG Baoji
Принадлежит:

A method for allocating resource and accessing in open wireless channels includes: covering multiple types of user terminal stations in open wireless channels; making dynamic adaptive matching according to comprehensive change factors of a transmitting end and a receiving end in each communication process. The factors of the transmitting end mean that a type and transmitting capacity of a transmitting station are changed, a current state of the wireless channel between the transmitting station and a relay node is changed, a working state of a receiving end of the relay node is changed, and user services to be transmitted are changed; the factors of the receiving end mean that a type and receiving capacity of a receiving station are changed, a current state of the channel from the relay node to the receiving station is changed, and a working state of a transmitting end of the relay node is changed. 1. A method for allocating resource and accessing in open wireless channels , comprising:covering multiple types of user terminal stations in the open wireless channels; andmaking dynamic adaptive matching with reference to comprehensive change factors of a transmitting end and comprehensive change factors of a receiving end in each communication process,wherein the comprehensive change factors of the transmitting end comprise changes of the following: a type and transmitting capacity of a transmitting station, a current state of the open wireless channels between the transmitting station and a relay node, a working state of a receiving end of the relay node, and user services to be transmitted by the transmitting station; andthe comprehensive change factors of the receiving end comprise changes of the following: a type and receiving capacity of a receiving station, a current state of the open wireless channels from the relay node to the receiving station, and a working state of a transmitting end of the relay node.2. The method according to claim 1 , further comprising: ...

Подробнее
Номер записи: 40
19-05-2016 дата публикации

COLON DISEASE TARGETS AND USES THEREOF

Номер: US20160137705A1
Автор: DOMON Bruno, HE Tao, LI Aiqun, MCCAFFREY Ian
Принадлежит:

The present invention provides a method for diagnosing and detecting diseases associated with colon. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in colon diseases (CCAT) and antibodies binds to CCAT. The present invention provides that CCAT is used as targets for screening agents that modulates the CCAT activities. Further the present invention provides methods for treating diseases associated with colon. 1. An isolated protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-683 and 1332-1501.2. A composition comprising the protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:684-1331;b) nucleotide sequences that encode a protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-683 and 1332-1501; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 , or transgenic organism that produces the antibody of .8. The antibody of claim 5 , wherein the antibody is coupled to a composition selected from the group consisting of detectable substances and therapeutic agents.9. A composition comprising the antibody of and a pharmaceutically acceptable carrier.10. An isolated antibody fragment of the antibody of claim 5 , wherein the antibody fragment comprises a fragment selected from the group ...

Подробнее
Номер записи: 41
01-09-2022 дата публикации

METHOD FOR QUASI-SYNCHRONOUS CODE DIVISION MULTIPLE ACCESS BASED ON SYNCHRONIZATION CLOCK BY PILOTING

Номер: US20220278744A1
Автор: DONG Mingke, HE Tao, JIN Ye, LIU Aimin, LV Guocheng, WANG Baoji
Принадлежит:

A method for quasi-synchronous code division multiple access based on synchronization clock by piloting can make CDMA operate in quasi-synchronous conditions, so it is suitable for open wireless channels with relay nodes, such as satellite communication systems, and open wireless channels without relay nodes. The method includes: adopting a mode of CDMA spread spectrum transmission to share power resources to transmit signals at multiple transmitting stations in open wireless channels; adopting an external pilot signal to provide synchronization clock for the CDMA signals transmitted by multiple terminal stations in the open wireless channels, eliminating path delay differences from the multiple terminal stations to a relay node or receiving station, and making multi-channel CDMA signals received at the relay node or receiving station clock synchronized and phase aligned. The method can realize the quasi-synchronous reception of multi-channel CDMA signals. 1. A method for quasi-synchronous code division multiple access (CDMA) based on a synchronization clock by piloting , comprising:adopting a mode of CDMA spread spectrum transmission to share power resources to transmit signals at multiple transmitting stations in open wireless channels;adopting an external pilot signal to provide the synchronization clock for CDMA signals transmitted by multiple terminal stations in the open wireless channels;eliminating path delay differences from the multiple terminal stations to a relay node or a receiving terminal station; andmaking multi-channel CDMA signals received at the relay node or the receiving terminal station realize a clock synchronization and a phase alignment, so as to realize a quasi-synchronous reception of the multi-channel CDMA signals.2. The method according to claim 1 , whereinthe external pilot signal comprises stable and continuous synchronization clock information and continuous reference timing information;the method further comprises receiving the ...

Подробнее
Номер записи: 42
26-05-2016 дата публикации

CHASSIS

Номер: US20160150666A1
Автор: HAN HE-TAO, JING XIAO-ZHONG, LIN YI-SHENG, SHU YUAN-GANG, TAN JUN-HUA, WANG Liang-Chin, XU CHUN-YONG
Принадлежит:

A chassis includes a shell, two sliding rails, a slider and a bracket. The two sliding rails are fixed to the shell. The slider is slidably fixed to one of the two sliding rails. The slider includes a positioning post. The bracket defines a groove. The positioning post is located in the groove and moves from a first position to a second position along the groove. When the positioning post is located at the first position, the bracket is locked with the shell. When the positioning post is located at the second position, the bracket is unlocked from the shell and can move away relative to the shell. 1. A chassis comprising:a shell;two sliding rails secured to the shell;a slider slidably secured to one of the two sliding rails, and the slider comprising a positioning post; anda bracket defining a groove;wherein the positioning post is configured to move from a first position to a second position along the groove; when the positioning post is located at the first position, the bracket is engaged with the shell; and when the positioning post is located at the second position, the bracket is unlocked with the shell and is configured to move away from the shell.2. The chassis of claim 1 , wherein when the positioning post moving from the first position to the second position claim 1 , the positioning post moves along a first direction claim 1 , the bracket moves along a second direction relative to the shell claim 1 , and the first direction is substantially perpendicular to the second direction.3. The chassis of claim 2 , wherein the shell comprises a bottom plate claim 2 , and the second direction is parallel to the bottom plate.4. The chassis of claim 1 , wherein the groove defines a slot and a positioning groove claim 1 , the slot communicates with the positioning groove claim 1 , and an extending direction of the slot is substantially perpendicular to an extending direction of the positioning groove.5. The chassis of claim 4 , wherein the bracket comprises cover claim ...

Подробнее
Номер записи: 43
17-06-2021 дата публикации

ALEXNET-BASED INSULATOR SELF-EXPLOSION RECOGNITION METHOD

Номер: US20210182615A1
Автор: CHEN Jianxin, Chen Junji, HE Tao, Huang Liang, Jiang Qinzhi, Li Yingguo, Mao Xinru, Xia Weijian, Yang Hong, Yang Hongchun, Yin Shucai, ZHOU JIE
Принадлежит: Yongchuan Power Supply Branch, State Grid Chongqing Electric Power Company

The present disclosure provides an AlexNet-based insulator self-explosion detection method using an unmanned aerial vehicle (UAV), including: acquiring image and video information collected by a robot patrolling and spanning an obstacle on a wire and the UAV; performing rapid data augmentation on the acquired image and video information based on an existing training data set, to divide the data set into two parts, which are respectively a training set and a test set; extracting an image feature and a class tag from the training data set and the test data set for classification; and training, by using the obtained training set and test set, a support vector machine (SVM) detection model that can recognize insulator self-explosion and that is obtained based on AlexNet. The detection model can recognize the acquired image and video information, to determine whether there is a self-exploded insulator based on the image and video information. 1step 1: acquiring image and video information collected by a robot patrolling and spanning an obstacle on a wire and an unmanned aerial vehicle (UAV);step 2: performing rapid data augmentation on the acquired image and video information based on an existing training data set, to divide the data set into two parts, which are respectively a training set and a test set;step 3: extracting an image feature and a class tag from the training data set and the test data set for classification; andstep 4: training, by using the obtained training set and test set, a support vector machine (SVM) detection model that can recognize insulator self-explosion and that is obtained based on AlexNet, wherein the insulator self-explosion recognition model performs classification based on whether an insulator is self-exploded.. An AlexNet-based insulator self-explosion recognition method, comprising the following steps: The present disclosure belongs to the technical field of electric power maintenance, in particular, to provide an AlexNet-based ...

Подробнее
Номер записи: 44
01-06-2017 дата публикации

ARRAY SUBSTRATE AND THE DRIVING METHOD THEREOF

Номер: US20170154561A1
Автор: Chen Yu-Yeh, He Jhen-Wei, HE Tao
Принадлежит: Shenzhen China Star Optoelectronics Technology Co. Ltd.

An array substrate and the driving method are disclosed. The array substrate includes a plurality of scanning lines arranged along a row direction, a plurality of data lines arranged along a column direction, and a plurality of sub-pixels arranged in a matrix defining by the scanning lines and the data lines. The sub-pixels are divided into a plurality of sub-pixel rows of different colors arranged periodically along the column direction, wherein at least one sub-pixel row is a compensation photon sub-pixel row. Within the same frame, a driving voltage polarity of two adjacent data lines of the compensation photon sub-pixel row is opposite to each other. In this way, the brightness change is decreased so as to enhance the image quality. 1. An array substrate of liquid crystal panels , comprising:a plurality of scanning lines arranged along a row direction, a plurality of data lines arranged along a column direction, and a plurality of sub-pixels arranged in a matrix defining by the scanning lines and the data lines, the scanning lines and the data lines correspond to the black matrixes of a color film substrate of the liquid crystal panel, the sub-pixels are divided into a plurality of sub-pixel rows of different colors arranged periodically along the column direction, wherein at least one sub-pixel row is a compensation photon sub-pixel row, within the same frame, a driving voltage polarity of two adjacent data lines of the compensation photon sub-pixel row is opposite to each other, and within the same frame, the driving voltage polarity of each of the sub-pixel rows within each arranging periods is opposite to that of the sub-pixels of corresponding color within adjacent arranging period; andthe compensation photon sub-pixel row is a yellow sub-pixel row.2. The array substrate claimed in claim 1 , wherein the sub-pixels is divided into a first base-color sub-pixel row claim 1 , a second base-color sub-pixel row claim 1 , a third base-color sub-pixel row claim 1 , ...

Подробнее
Номер записи: 45
11-06-2015 дата публикации

METHOD, APPARATUS AND SERVER FOR IDENTITY AUTHENTICATION

Номер: US20150163216A1
Автор: HUANG HE TAO, Xu Dong Shan
Принадлежит:

The disclosure relates to a method, apparatus and server for identity authentication, related to communication technique to solve system overload problem caused by invalid access ID attack. The method may include: a server receiving an API calling request from third party developer, the API calling request carrying access ID generated in advance by server and assigned to the third party developer; searching for a version character carried in the access ID; based on a version character generation rule, verifying whether the version number marked by the version character being the same as a version number of the check character generation rule used by the server; when the version character being verified successfully, searching for at least a check character carried in the access ID; and based on the check character generation rule, verifying respectively on the at least a check character. The disclosure is applied to API calling request process. 1. A method for identity authentication , at a server side , the method comprising:receiving an API calling request from a third party developer, the API calling request carrying an access identification (access ID) generated in advance by the server and assigned to the third party developer;searching for a version character carried in the access ID, the version character being for marking a version number of a check character generation rule;based on a version character generation rule, verifying whether the version number marked by the version character being the same as a version number of the check character generation rule used by the server;when the version character being verified successfully, searching for at least a check character carried in the access ID; andbased on the check character generation rule, verifying respectively on the at least a check character.2. The method for identity authentication as claimed in claim 1 , wherein claim 1 , before the step of a server receiving an API calling request from a third ...

Подробнее
Номер записи: 46
28-08-2014 дата публикации

Red light-emitting nitride material, and light-emitting part and light-emitting device comprising the same

Номер: US20140239800A1
Автор: He Huaqiang, HE Tao, Hu Yunsheng, Li Nan, Liu Ronghui, Liu Yuanhong, Zhuang Weidong
Принадлежит: GRIREM ADVANCED MATERIALS CO., LTD

Disclosed are a red light-emitting nitride material, a light-emitting part and a light-emitting device comprising the same. The General Formula of the light-emitting material is: M(Al,B)SiNO:Eu, R, wherein M is at least one of the alkaline earth metal elements Mg, Ca, Sr, Ba and Zn; R is at least one of the rare earth elements Y, La, Ce, Gd and Lu; and 0.9≦a<1.1, 0.9≦b≦1, 1≦c≦1.5, 2.5 Подробнее

Номер записи: 47
09-06-2016 дата публикации

METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING DISEASES

Номер: US20160161494A1
Автор: BIRSE Charles, DOMON Bruno, HE Tao, JOSELOFF Elizabeth, LEE Candy, MCKINNON Katherine, MESRI Mehdi, MOORE Paul, RUBEN Steve, VAN ORDEN Karen
Принадлежит:

Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro. 1. An isolated CAT protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-4 , 9 , 11-12 , 16-19 , 24-36 , 51-59 , 69-74 , 81-85 , 91-102 , 115-116 , 119-121 , 127-134 , 144-145 , 148-149 , 152-159 , 168-174 , and 182-183.2. A composition comprising the CAT protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:5-8, 10, 13-15, 20-23, 37-50, 60-68, 75-80, 86-90, 103-114, 117-118, 122-126, 135-143, 146-147, 150-151, 160-167, 175-181, 184-185;b) nucleotide sequences that encode a CAT protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-4, 9, 11-12, 16-19, 24-36, 51-59, 69-74, 81-85, 91-102, 115-116, 119-121, 127-134, 144-145, 148-149, 152-159, 168-174, and 182-183; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the CAT protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 , or transgenic organism that produces the antibody of .8. The antibody of claim 5 , wherein the antibody is coupled to a composition selected from the group consisting of detectable substances and therapeutic ...

Подробнее
Номер записи: 48
04-09-2014 дата публикации

LIGHT EMITTING DIODE (LED) RED FLUORESCENT MATERIAL AND LIGHTING DEVICE HAVING THE SAME

Номер: US20140246693A1
Автор: He Huaqiang, HE Tao, Hu Yunsheng, Liu Ronghui, Liu Yuanhong
Принадлежит: GRIREM ADVANCED MATERIALS CO., LTD.

Provided are a Light Emitting Diode (LED) red fluorescent material and a lighting device having the same. The florescent material consists of elements M, A, D, X, L and Z, wherein element M at least contains one or more than one element of Be, Mg, Ca, Sr, Ba and Zn; element A at least contains one or more than one element of B, Al, Ga, In, La, Gd, Lu, Sc and Y; element D at least contains one or more than one element of Si, Ge, C, Sn, Ti, Zr and Hf; element X at least contains one or more than one element of N, O and F; element L at least contains one or more than one element of S, Se and Te; and element Z at least contains one or more than one element of a rare earth element or a transition-metal element. 118-. (canceled)19. A Light Emitting Diode (LED) red fluorescent material , comprising:an element M, wherein the element M contains at least one element of Be, Mg, Ca, Sr, Ba, and Zn;an element A, wherein the element A contains at least one element of B, Al, Ga, In, La, Gd, Lu, Sc and Y;an element D, wherein the element D contains at least one element of Si, Ge, C, Sn, Ti, Zr and Hf;an element X, wherein the element X contains at least one element of N, O, and F;an element L, wherein the element L contains at least one element of S, Se, and Te; andan element Z, wherein the element Z contains at least one of a rare-earth element and a transition-metal element.20. The LED red fluorescent material according to claim 19 , further comprising a formula of MADXL:Z claim 19 , wherein 0.5≦m≦1.5 claim 19 , 0.5≦a≦1.5 claim 19 , 0.5≦b≦1.5 claim 19 , 2≦d≦5 claim 19 , 0.00001≦y≦0.02 claim 19 , and 0.0001≦n≦0.1.21. The LED red fluorescent material according to claim 19 , wherein the element M contains at least one element of Ca claim 19 , Sr and Ba; the element A contains at least one element of Al claim 19 , B claim 19 , Gd and Y; the element D contains at least one element of Si and C; the element X contains at least one element of N and O; the element L contains the element ...

Подробнее
Номер записи: 49
24-06-2021 дата публикации

QUESTION CORRECTION METHOD, DEVICE, ELECTRONIC EQUIPMENT AND STORAGE MEDIUM FOR ORAL CALCULATION QUESTIONS

Номер: US20210192965A1
Автор: CHEN Mingquan, HE Tao, LUO Huan, Shi Fan
Принадлежит: Hangzhou Dana Technology Inc.

The present disclosure provides a question correction method and device for oral calculation questions. The feature vector of the question to be searched is obtained according to the content of token in the stem of each question to be searched, and then the feature vector of each question to be searched is used to search for the target test paper that matches the test paper to be searched in the question bank. For the question to be searched in the form of oral calculation question, a second search is performed in the target test paper based on the feature vector of the question, and the search criterion is the minimum shortest editing distance. If the question type of the matched target question is also an oral calculation question, it is determined that the question to be searched is the oral calculation question to be corrected, then a preset oral calculation engine is used to calculate the oral calculation question to be corrected and the calculation result is output as the answer to the oral calculation question to be corrected. By applying the solution provided by the present disclosure, the accuracy of correction on oral calculation questions can be improved. 1. A question correction method for oral calculation questions , wherein the method comprises:{'b': '11', 'step S: detecting an image of a test paper to be searched, detecting an area of each question to be searched on the test paper to be searched, determining a type of said each question to be searched, and identifying the content of token in a stem in the area of said each question to be searched;'}{'b': '12', 'step S: obtaining a feature vector of the question to be searched according to the content of token in the stem of said each question to be searched, and conducting search in a question bank according to the feature vector of the question to be searched to find a question most similar to the question to be searched;'}{'b': '13', 'step S: summarizing all the test papers with the question most ...

Подробнее
Номер записи: 50
15-06-2017 дата публикации

Method of downloading configuration code, system and timer/counter control register

Номер: US20170168850A1
Автор: Jianjun Xie, Lei Sun, Tao He, Wenqin Zhao, Xiaobin BI
Принадлежит: Shenzhen China Star Optoelectronics Technology Co Ltd

The present invention provides a method of downloading a configuration code, applied in a timer/counter control register, and the method comprises steps of acquiring a first boot code through a first default interface of the timer/counter control register; calculating a first check code according to the acquired first boot code; determining whether the calculated first check code and a first standard check code are the same; as the two are the same, downloading the configuration code from the storage element coupled to the first default interface through the first default interface; as the two are different, downloading the configuration code from a storage element coupled to a second default interface through the second default interface of the timer/counter control register. Therefore, the present invention promote the utility flexibility of the timer/counter control register. The present invention further provides a system of downloading a configuration code and a timer/counter control register.

Подробнее
Номер записи: 51
01-07-2021 дата публикации

REAMING TYPE NON-IMPLANTED ATRIAL SHUNT DEVICE

Номер: US20210196373A1
Автор: Cai Jie, Chen Hao, DING Yishou, He Ping, HE Tao, LI Xiangyi, Liu Liyun, PU Zhongjie, ZHANG Xibo, ZHANG Yuxin
Принадлежит:

The application relates to a reaming type non-implanted atrial shunt device comprising a catheter component (), a radio frequency component () disposed on an end of the catheter component () extending into a human body, and a radio frequency ablation instrument () disposed on the other end of the catheter component () and connected with the radio frequency component (), wherein after the radio frequency component () extends into a puncture hole, the radio frequency ablation instrument () releases a radio frequency energy, and the radio frequency component () ablates a wall of the puncture hole. The radio frequency component () is delivered to the position of the puncture hole. When the radio frequency ablation instrument () releases energy, the radio frequency component () causes the hole wall tissue to generate heat and ablate the atrial septum at a target position to form a hole with fixed size, thereby achieving the purpose of creating a hole. Using radio frequency components () to create a hole through radio frequency make the hole not easy to reclose. The hole can effectively drain the left atrium blood into the right atrium, reduce pressure of the left atrium, thereby achieving the purpose of treatment. 1. A reaming type non-implanted atrial shunt device , comprisinga catheter component,a radio frequency component, disposed on an end of the catheter component extending into a human body, anda radio frequency ablation instrument, disposed on the other end of the catheter component and connected with the radio frequency component, whereinafter the radio frequency component extends into a puncture hole, the radio frequency ablation instrument releases a radio frequency energy, and the radio frequency component ablates a wall of the puncture hole.2. The reaming type non-implanted atrial shunt device according to claim 1 , whereinthe radio frequency component comprises a balloon that expands by charging pressure or retracts by discharging pressure, and an electrode ...

Подробнее
Номер записи: 52
18-09-2014 дата публикации

METHOD FOR MEASURING AMOUNTS OF COMPONENTS AND CALORIFIC VALUE OF COAL GAS

Номер: US20140262836A1
Автор: HE Tao, Liu Zhiqiang, SHI Pingjing, XIONG Youhui
Принадлежит: Wuhan Cubic Optoelectronics Co., Ltd.

A method for measuring the component and calorific value of goal gas. The method includes measuring a volume concentration of H(T) using a thermal conductivity detector (TCD), measuring a volume concentration of Ousing an electrochemical detector (ECD), measuring volume concentrations of CO, CO, CH, and CHin the coal gas, revising an interference of CHin CH, revising a measured volume concentration of H, and calculating the calorific value of the coal gas. 1. A method for measuring components and calorific value of coal gas , the method comprising the following steps:{'sub': 2', 'H2', '2, '1) measuring a volume concentration of H(T) using a thermal conductivity detector (TCD), measuring a volume concentration of Ousing an electrochemical detector (ECD);'}{'sub': 2', '4', 'n', 'm', 'CO', 'CO2', 'CH4', 'CnHm, '2) measuring volume concentrations of CO, CO, CH, and CHin the coal gas, represented by T, T, T, and T, respectively, using a non-dispersive infrared (NDIR) technology;'}{'sub': 4', 'n', 'm', 'CnHm', 'CnHm', 'CH4', 'CnHm', 'CH4', 'n', 'm', '4, '3) revising an interference of CHin CHusing an equation R=T−A×T, in which, A represents an undetermined coefficient, and Tand Trepresent the volume concentrations of CHand CHmeasured with the NDIR, respectively;'}{'sub': 2', 'H2', 'H2', 'CH4', 'CnHm', 'CO2', 'H2', '2', 'CH4', 'CO2', '4', '2', 'CnHm', 'n', 'm, '4) revising a measured volume concentration of Husing the equation R=T−a×(T+R)−b×T, in which, Trepresents the measured volume concentration of Husing the TCD, Tand Trepresent the volume concentrations of CHand COmeasured using the NDIR, respectively, Rrepresents a revised volume concentration of CH, and a and b represents undetermined coefficients; and'}{'sub': CO', 'H2', 'CH4', 'CnHm', 'CO', 'CH4', 'H2', 'CnHm, '5) calculating the calorific value of the coal gas using the equation Q=T×12.64+R×18.79+T×35.88+R×93.18, in which, Tand Trepresent measured volume concentrations, and Rand Rrepresent revised volume ...

Подробнее
Номер записи: 53
06-06-2019 дата публикации

COATING FOR GLASS AND FORMING METHOD THEREOF, AND AUTOMOTIVE WINDOW

Номер: US20190169067A1
Автор: GU Yunxin, HE Tao, Shi Ce
Принадлежит:

A coating for a glass and a forming method thereof, and an automotive window are provided. The coating includes: a first material layer which has a first elastic modulus; and a second material layer which includes at least one material layer, wherein the second material layer has a first surface and a second surface opposite to the first surface, the first surface is used for disposing the first material layer, the second surface is adaptable for facing a surface of the glass when the coating is applied on the glass, and the second material layer has a second elastic modulus less than the first elastic modulus. Anti-scratch ability of the coating and scratch resistance of the automotive window may be improved, which avoids scratches on the automotive window. 1. A coating for a glass , comprising:a first material layer having a first elastic modulus; anda second material layer comprising at least one material layer, wherein the second material layer has a first surface and a second surface opposite to the first surface, the first surface is used for disposing the first material layer, the second surface is adaptable for facing a surface of the glass when the coating is applied on the glass, and the second material layer has a second elastic modulus less than the first elastic modulus.2. The coating according to claim 1 , wherein a ratio of the first elastic modulus to the second elastic modulus is greater than or equal to 10.3. The coating according to claim 1 , wherein the first elastic modulus is greater than 100 Mpa under a room temperature and a quasi-static condition.4. The coating according to claim 1 , wherein the second elastic modulus is less than 50 Mpa under a room temperature and a quasi-static condition.5. The coating according to claim 1 , wherein a thickness of the second material layer is greater than a thickness of the first material layer.6. The coating according to claim 1 , wherein a thickness of the second material layer is less than or equal to ...

Подробнее
Номер записи: 54
06-06-2019 дата публикации

Eye-safe laser triangulation measurement system

Номер: US20190170877A1
Автор: DING Huang, Jianfei Zhang, Lei Zhao, Liyuan LIU, Qiang Wang, Runxi ZHANG, Tao He, Wenlong Liao
Принадлежит: Anhui Cowarobot Co ltd

The present disclosure provides an eye-safe laser triangulation measurement system, including a laser transmitter, an optical projection apparatus, a laser beam capturing unit, a cooperation unit, and an image processing apparatus. The laser transmitter is configured to generate point pulse laser of a pulse laser beam. The optical projection apparatus is disposed at a front end of the laser transmitter, and is configured to convert the point pulse laser into a line laser. The laser beam capturing unit is configured to capture reflected light obtained by the line laser at a target position to obtain a laser image. The cooperation unit is configured to control on and off of the laser transmitter, and control capture of the laser beam capturing unit. The image processing apparatus is configured to perform 3D modeling on the laser image to obtain a distance to the target position.

Подробнее
Номер записи: 55
28-05-2020 дата публикации

SEALS AND ASSEMBLIES WITH SEALS

Номер: US20200166139A1
Автор: HE Tao, JIN Si, Wang Hongyan, WEI Wei
Принадлежит:

An annular seal comprising: a central section; a first seal interface extending from a first axial side of the central section; and a second seal interface extending from a second axial side of the central section, wherein the first and second seal interfaces each include less than three sealing lips, and wherein at least a portion of the central section is adapted to be spaced apart from a surface of a hardware in an installed state. 1. An annular seal comprising:a central section;a first seal interface extending from a first axial side of the central section; anda second seal interface extending from a second axial side of the central section, 'wherein at least a portion of the central section is adapted to be spaced apart from a surface of a hardware in an installed state.', 'wherein the first and second seal interfaces each include less than three sealing lips, and'}2. The annular seal of claim 1 , wherein at least one of the first and second seal interfaces comprises an energizing element.3. The annular seal of claim 1 , wherein the second seal interface comprises an energizing element claim 1 , and wherein the first seal interface is essentially free of an energizing element.4. The annular seal of claim 3 , wherein the annular seal is adapted to be disposed between a first region of a hardware and a second region of a hardware claim 3 , wherein the first region has a higher pressure than the second region claim 3 , and wherein the second seal interface is adapted to be disposed on a side of the annular seal closer to the first region.5. The annular seal of claim 1 , wherein the sealing lips comprise an edge lip adjacent to an axial end of the annular seal and a secondary lip spaced apart from the edge lip by a recessed portion.6. The annular seal of claim 5 , wherein the recessed portion has a generally polygonal cross section.7. The annular seal of claim 5 , wherein the recessed portion comprises a first surface and a second surface claim 5 , wherein the ...

Подробнее
Номер записи: 56
20-06-2019 дата публикации

METHOD FOR CONTROLLING SET-TOP BOX GAME, REMOTE CONTROL SYSTEM, AND HANDHELD ELECTRONIC APPARATUS

Номер: US20190184281A1
Автор: Chen Linfeng, HE Tao, Li Xin, SHANG Yaowei, WANG Jian
Принадлежит: Shanghai Zhaoxin Semiconductor Co., Ltd.

A method for controlling STB game, a remote control system and a handheld electronic apparatus are provided. After the handheld electronic apparatus is connected to the STB, when a gamepad mode is enabled, a virtual gamepad interface is displayed through a touch display panel of the handheld electronic apparatus, so as to simulate an operation method of a real gamepad. When the screen capturing mode is enabled, a game image of the display is captured and displayed on the touch display panel of the handheld electronic apparatus, and a specific function set in the game image is controlled through the touch display panel. 1. A method for controlling set-top box game , comprising:connecting a handheld electronic apparatus with a set-top box, wherein the handheld electronic apparatus comprises a touch display panel and provides a gamepad mode and a screen capturing mode, and the set-top box is installed with an electronic game and is configured to present a game image on a display;after the handheld electronic apparatus is connected to the set-top box, when the gamepad mode is enabled, displaying a virtual gamepad interface through the touch display panel, wherein the virtual gamepad interface comprises a plurality of virtual function keys, and an operation method of a real gamepad is simulated through the virtual function keys; andafter the handheld electronic apparatus is connected to the set-top box, when the screen capturing mode is enabled, capturing the game image of the display and displaying the game image on the touch display panel, and controlling a specific function set in the game image through the touch display panel.2. The method for controlling set-top box game as claimed in claim 1 , wherein after the step of displaying the virtual gamepad interface through the touch display panel claim 1 , the method further comprises:when the set-top box receives a keystroke event of the virtual gamepad interface from the handheld electronic apparatus, converting the ...

Подробнее
Номер записи: 57
14-07-2016 дата публикации

Method and Apparatus for Assessing Treatment Effectiveness of Tooth Sensitivity with an Oral Care Product

Номер: US20160202137A1
Автор: Donald James White, Jr., Jinlan CHANG, LEI Tian, Nixon Lao Ocampochua, Ross Strand, Tao He, Yanyan He, Yunming Shi
Принадлежит: Procter and Gamble Co

An apparatus ( 40 ) for assessing treatment effectiveness of tooth sensitivity with an oral care product comprising a tooth shaped member ( 50 ) comprises an outer layer ( 60 ) simulating an enamel, wherein the outer layer ( 60 ) at least partially covers an exterior surface of an inner layer ( 70 ) simulating a pulp, and a liquid sensor ( 80 ) contained either between the outer layer ( 60 ) and inner layer ( 70 ), or within the inner layer ( 70 ); and a plurality of holes ( 90 ), simulating open dentin tubules, configured through the outer layer ( 60 ) to the inner layer ( 70 ), and in fluid communication with the liquid sensor ( 80 ); wherein the liquid sensor ( 80 ) is configured to sense liquid passing through at least one of the plurality of holes ( 90 ) as simulating the treatment effectiveness of tooth sensitivity of the oral care product.

Подробнее
Номер записи: 58
22-07-2021 дата публикации

ANSWER CORRECTION METHOD AND DEVICE

Номер: US20210225188A1
Автор: CHEN Mingquan, HE Tao, LUO Huan, MAO Lihui
Принадлежит: Hangzhou Dana Technology Inc.

The disclosure provides an answer correction method and a device, including: determining the target test paper that matches the test paper to be corrected; marking the area of each answer in the test paper to be corrected as the first answer set, and marking the area of each answer in the target test paper as the second answer set; matching each answer area in the first answer set and the second answer set, and adjusting the position of the answer area in the first answer set on the test paper to be corrected; for each answer area in the second answer set, determining the target answer area in the first answer set according to the position information of the answer area on the target test paper, and correcting the answer in the determined target answer area according to the answer in the answer area. The disclosure can solve the problem in the related art that the accurate position of the answer filled by the student cannot be identified, thereby affecting the correction of the answer. 1. An answer correction method , the method comprises:searching in a question bank according to a test paper to be corrected to determine a target test paper that matches the test paper to be corrected;marking each answer area on the test paper to be corrected as a first answer set, and marking each answer area on the target test paper as a second answer set;utilizing a first preset algorithm to preliminarily match the each answer area in the first answer set with the each answer area in the second answer set, and adjusting a position of a preliminarily matched answer area in the first answer set on the test paper to be corrected according to a position of an answer area in the second answer set on the target test paper;for the each answer area in the second answer set, determining a target answer area in the first answer set according to position information of the answer area in the second answer set on the target test paper, and correcting an answer in the determined target answer ...

Подробнее
Номер записи: 59
04-07-2019 дата публикации

SYSTEMS AND METHODS FOR MONITORING A MEDICAL DEVICE

Номер: US20190200948A1
Автор: FAN Zhouyuan, HE Tao, Li Bing, Zhou Jiawen, Zhou Pei
Принадлежит: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.

The present disclosure is related to systems and methods for monitoring a medical device. The medical device may include a tube configured to generate radiation rays and a detector configured to receive radiation rays emitted from the tube. The tube may include an anode target and a filament. The detector may include a plurality of detecting units. The method may include obtaining imaging data acquired by the detector via detecting radiation rays emitted from the tube. The method may also include determining a first feature parameter associated with the radiation rays based on the imaging data. The method may further include monitoring the medical device based on the first feature parameter associated with the radiation rays. 1. A system for monitoring a medical device including a tube configured to generate radiation rays and a detector configured to receive radiation rays emitted from the tube , the tube including an anode target and a filament , the detector including a plurality of detecting units , comprising:a computer-readable storage medium storing executable instructions, and obtain imaging data acquired by the detector via detecting radiation rays emitted from the tube;', 'determine a first feature parameter associated with the radiation rays based on the imaging data; and', 'monitor the medical device based on the first feature parameter associated with the radiation rays., 'at least one processor in communication with the computer-readable storage medium, when executing the executable instructions, causing the system to2. The system of claim 1 , wherein the imaging data includes an intensity of radiation rays received by each of the plurality of detecting units and a position of each of the plurality of detecting units claim 1 , and to determine a first feature parameter associated with the radiation rays based on the imaging data claim 1 , the at least one processor is further configured to cause the system to:determine an intensity distribution of the ...

Подробнее
Номер записи: 60
26-07-2018 дата публикации

CIRCUITS AND METHODS FOR INTER-SYMBOL INTERFERENCE COMPENSATION

Номер: US20180212617A1
Автор: Ashburn, HE Tao, JR. Michael A.
Принадлежит:

Circuits and methods for inter-symbol interference compensation are described. These circuits and methods may be used in connection with delta-sigma analog-to-digital converter. During a sensing phase, a value indicative of the inter-symbol interference may be sensed. The value may be obtained by (1) causing the ADC to generate a first number of transitions during a first time interval; (2) causing the ADC to generate a second number of transitions during a second time interval; (3) sensing the number of logic-0s and logic-1s occurring in the first and second time intervals; and (4) computing the value based at least in part on the number of logic-0s and logic-1s occurring in the first and second time intervals. During a compensation phase, inter-symbol interference may be compensated based on the value obtained in the sensing phase. 1. (canceled)2. A method for compensating a circuit for inter-symbol interference (ISI) , the method comprising: causing the circuit to generate a first data stream having a first number of transitions, and', 'determining a first number of zeros and/or ones that are output by the circuit in the first time interval;, 'in a first time interval causing the circuit to generate a second data stream having a second number of transitions, and', 'determining a second number of zeros and/or ones that are output by the circuit in the second time interval;, 'in a second time intervaldetermining a value indicative of an ISI by comparing the first number of zeros and/or ones with the second number of zeros and/or ones; andcompensating the circuit for inter-symbol interference based on the value,wherein the circuit comprises an analog-to-digital converter (ADC).3. The method of claim 2 , wherein the ADC comprises a delta-sigma ADC.4. A method for compensating a circuit for inter-symbol interference (ISI) claim 2 , the method comprising: causing the circuit to generate a first data stream having a first number of transitions, and', 'determining a ...

Подробнее
Номер записи: 61
26-07-2018 дата публикации

CIRCUITS AND METHODS FOR EXCESS LOOP DELAY COMPENSATIN IN DELTA-SIGMA MODULATORS

Номер: US20180212618A1
Автор: Ashburn, HE Tao, JR. Michael A.
Принадлежит:

Circuits for compensating delta-sigma modulators for excess loop delay are described. These circuits may be coupled to quantizers, and may configured to select the threshold values supplied to the quantizers for comparison with an analog signal. The threshold values may each be selected from a corresponding plurality of reference values, and may be set such that the numerical order of threshold values varies over time. For example, the threshold value provided to a first comparator of the quantizer may be greater than the threshold value provided to a second comparator of the quantizer in a first time interval, but the opposite scenario may occur in a second time interval. The circuits may include multiplexers for selecting the threshold values, thermometric encoders, reference selectors and reference multiplexers. 1. A method comprising: filtering the analog input signal with a filter;', 'generating the digital output by comparing, with a plurality of comparators, the filtered analog input signal to a plurality of threshold values;', 'selecting, based on a previous output of the plurality of comparators, at least one of the plurality of threshold values from a plurality of corresponding reference values, wherein selecting at least one of the plurality of threshold values comprises varying a numerical order of the plurality of threshold values over time; and', 'providing the digital output to an input port of the filter., 'converting an analog input signal into a digital output at least in part by2. The method of claim 1 , wherein the plurality of threshold values comprise at least a first and second threshold values claim 1 , and wherein:varying an order of the plurality of threshold value comprises setting the plurality of threshold values such that the first threshold value is greater than the second threshold value in a first time interval and the second threshold value is greater than the first threshold value in a second time interval.3. The method of claim 2 ...

Подробнее
Номер записи: 62
23-10-2014 дата публикации

METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING DISEASES

Номер: US20140314768A9
Автор: BIRSE Charles, DOMON Bruno, HE Tao, JOSELOFF Elizabeth, LEE Candy, MCKINNON Katherine, MESRI Mehdi, MOORE Paul, RUBEN Steve, VAN ORDEN Karen
Принадлежит: CELERA CORPORATION

Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro. 1. An isolated CAT protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-4 , 9 , 11-12 , 16-19 , 24-36 , 51-59 , 69-74 , 81-85 , 91-102 , 115-116 , 119-121 , 127-134 , 144-145 , 148-149 , 152-159 , 168-174 , and 182-183.2. A composition comprising the CAT protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:5-8, 10, 13-15, 20-23, 37-50, 60-68, 75-80, 86-90, 103-114, 117-118, 122-126, 135-143, 146-147, 150-151, 160-167, 175-181, 184-185;b) nucleotide sequences that encode a CAT protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-4, 9, 11-12, 16-19, 24-36, 51-59, 69-74, 81-85, 91-102, 115-116, 119-121, 127-134, 144-145, 148-149, 152-159, 168-174, and 182-183; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the CAT protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 , or transgenic organism that produces the antibody of .8. The antibody of claim 5 , wherein the antibody is coupled to a composition selected from the group consisting of detectable substances and therapeutic ...

Подробнее
Номер записи: 63
23-10-2014 дата публикации

KIDNEY DISEASE TARGETS AND USES THEREOF

Номер: US20140314770A1
Автор: HE Tao, JOSELOFF Elizabeth, RUBEN Steve
Принадлежит: CELERA CORPORATION

The present invention provides a method for diagnosing and detecting diseases associated with kidney. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in kidney diseases (KCAT) and antibodies binds to KCATs. The present invention provides that KCATs are used as targets for screening agents that modulates the KCAT activities. Further the present invention provides methods for treating diseases associated with kidney. 1. An isolated protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-2736 and 5165-6044.2. A composition comprising the protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:2737-5164;b) nucleotide sequences that encode a protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-2736 and 5165-6044; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 , or transgenic organism that produces the antibody of .8. The antibody of claim 5 , wherein the antibody is coupled to a composition selected from the group consisting of detectable substances and therapeutic agents.9. A composition comprising the antibody of and a pharmaceutically acceptable carrier.10. An isolated antibody fragment of the antibody of claim 5 , wherein the antibody fragment comprises a fragment selected from the ...

Подробнее
Номер записи: 64
18-07-2019 дата публикации

METHOD, DEVICE AND COMPUTER PROGRAM PRODUCT FOR DATA BACKUP

Номер: US20190220364A1
Автор: HE Tao, Ke Li, Li Na, YU Jing, Zhang Ming
Принадлежит:

The present disclosure relates to a data backup method and device, and a method, device and computer program product for managing data backup. The method for data backup implemented at the computing device comprises: receiving a backup message indicating that data backup is to be performed, the backup message indicating at least one of the following: a virtual machine to be backed up, an operating computing device of the virtual machine to be backed up, and a virtual disk to be backed up; determining, based on the backup message, a block device for which data backup is to be performed, the block device corresponding to at least a part of the virtual disk to be backed up; and performing incremental backup on data in the block device. 1. A method of data backup , comprising;receiving a backup message indicating that data backup is to be performed, the backup message indicating at least one of the following: a virtual machine to be backed up, and an operating computing device of the virtual machine to be backed up;determining, based on the backup message, a block device for which data backup is to be performed, the block device corresponding to at least a part of a virtual disk to be backed up associated with the virtual machine to be backed up or the operating computing device to be backed up; andperforming incremental backup on data in the block device.2. The method according to claim 1 , wherein determining a block device for which data backup is to be performed comprises:in response to determining that the operating computing device of the virtual machine to be backed up indicated by the backup message corresponds to the computing device, obtaining operation data of the virtual machine to be backed up; anddetermining, based on the operation data, a block device corresponding to at least the part of the virtual disk to be backed up.3. The method according to claim 1 , wherein performing incremental backup on the data comprises:initiating a session corresponding to ...

Подробнее
Номер записи: 65
18-07-2019 дата публикации

METHOD, APPARATUS AND COMPUTER PROGRAM PRODUCT FOR MANAGING DATA BACKUP

Номер: US20190220366A1
Автор: HE Tao, Ke Li, Li Jie, Wang Yun, YU Jing
Принадлежит:

Embodiments of the present disclosure relate to a method, apparatus and computer program product for managing a data backup. The method comprises determining a first data amount to be involved in an addressing operation and a second data amount to be involved in a copy operation for an extent to be backed up on a source storage device, the addressing operation addressing a starting address of the extent and the copy operation copying an amount of data corresponding to a length of the extent. The method further comprises obtaining, based on an identifier of the source storage device, a first historical time elapsed for a previous addressing operation having the first data amount and a second historical time elapsed for a previous copy operation having the second data amount. 1. A method of managing a data backup , comprising:determining a first data amount to be involved in an addressing operation and a second data amount to be involved in a copy operation for an extent to be backed up on a source storage device, the addressing operation addressing a starting address of the extent and the copy operation copying an amount of data corresponding to a length of the extent;obtaining, based on an identifier of the source storage device, a first historical time elapsed for a previous addressing operation having the first data amount and a second historical time elapsed for a previous copy operation having the second data amount; anddetermining a predicted time required for backing up the extent based on the first historical time and the second historical time.2. The method according to claim 1 ,wherein the extent is selected from a plurality of extents to be backed up that are non-continuous to each other, the method further comprising:determining a total predicted time required for backing up the plurality of extents based on the predicted time required for backing up the extent; andbacking up data on the source storage device based on the total predicted time.3. The ...

Подробнее
Номер записи: 66
25-08-2016 дата публикации

DIRECT SYNTHESIS OF PH-RESPONSIVE POLYMER PARTICLES AND APPLICATION IN CONTROL RELEASE OF HYDROPHOBIC THERAPEUTIC COMPOUNDS

Номер: US20160244546A1
Автор: HE Tao, Kim Sanggu, STUBBS Ludger Paul
Принадлежит:

The present disclosure relates to a process for making a branched copolymer comprising reacting polymer monomers with macro-azo polyethylene glycol (PEG) initiators and cross-linkers, in the presence of a chain transfer agent, wherein said process comprises the step of traditional radical polymerization. The process further comprises a step of dialysis to obtain polymer nano-particles. The process further comprises the step of loading the polymer nanoparticles with a hydrophobic compound. The present disclosure also relates to the use of the polymer nanoparticles for the slow release of a hydrophobic compound in a neutral or alkaline environment or the fast release of a hydrophobic compound in an acidic environment. 1. A process for making a branched copolymer comprising reacting polymer monomers with macro-azo polyethylene glycol (PEG) initiators and cross-linkers , in the presence of a chain transfer agent , wherein said process comprises the step of traditional radical polymerization.2. The process according to claim 1 , wherein said polymer monomer is selected from the group consisting of acrylates.3. The process according to claim 1 , wherein said acrylate is selected from the group consisting of dimethylamino ethyl methacrylate claim 1 , diethylamino ethyl methacrylate claim 1 , acrylic acid claim 1 , and derivatives thereof.4. The process according to claim 1 , wherein said macro-azo PEG has varied molecular weight of PEG of between 12 claim 1 ,000 to 20 claim 1 ,000.5. The process according to claim 1 , wherein said cross-linker is selected from the group consisting of ethylene glycol dimethacrylate (EGDMA) claim 1 , 2-isocyanatoethyl methacrylate claim 1 , N claim 1 ,N′-methylenebis(acrylamide).6. The process according to claim 1 , wherein said chain transfer agent is selected from the group consisting of 1-dodecanethiol (DDT) and cyanomethyl benzodithioate.7. The process according to claim 1 , wherein the ratio of initiator/chain transfer agent/cross- ...

Подробнее
Номер записи: 67
23-07-2020 дата публикации

CAPPED AND UNCAPPED ANTIBODY CYSTEINES, AND THEIR USE IN ANTIBODY-DRUG CONJUGATION

Номер: US20200230256A1
Автор: HE Tao, Kriz Ronald William, Letendre Leo Joseph, Prashad Amarnauth Shastrie, Somers Will, Wang Wenge, Zhong Xiaotian
Принадлежит: PFIZER INC.

An antibody production process in mammalian cells in which engineered unpaired cysteine residues are post-translationally modified and capped with particular chemical entities, which capped antibodies are well suited to further site-specific conjugation steps to form antibody-drug conjugates (ADCs) or protein drug conjugates; ADCs produced using these capped antibodies including in particular ADCs formed by the selective reduction of the capped antibodies' cysteine residues, and ADCs formed using chemical handles such as aldehyde/azide/alkyne biorthogonal groups, which permit additional drug conjugation chemistry; and uncapped antibodies produced by cells in low cysteine, cysteine and glutathione media, and ADCs produced via direct conjugation to these uncapped antibodies. 120-. (canceled)22. The method of claim 22 , wherein said cytotoxic payload is selected from the group consisting of auristatins claim 22 , calicheamicins claim 22 , maytansinoids claim 22 , spliceostatins claim 22 , CBI dimers claim 22 , CPI dimers claim 22 , and CTI dimers.23. A method of producing an antibody drug conjugate (ADC) comprising the steps:(a) producing a capped antibody in a cell culture, wherein one or more unpaired cysteine residues on said antibody are covalently bonded through sulfur bonds to one or more predetermined capping moieties, wherein said predetermined capping moieties are selected from the group consisting of: maleimido trioxa-4-formyl benzamide (MTFB), dibenzocyclooctyl-polyethylene maleimide (DBCO-PEG4-Maleimide), and azido-PEG3-maleimide; and(b) optionally further reacting said predetermined capping moiety on said capped antibody. The invention is based on the discovery that the capping status of cysteine residues on antibodies can be modified in live cells. Thus the invention relates to antibody production process in mammalian cells in which engineered unpaired cysteine residues are post-translationally modified and capped with particular chemical entities, which ...

Подробнее
Номер записи: 68
01-08-2019 дата публикации

Kidney disease targets and uses thereof

Номер: US20190233484A1
Автор: Elizabeth Joseloff, Steve Ruben, Tao He
Принадлежит: Celera Corp

The present invention provides a method for diagnosing and detecting diseases associated with kidney. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in kidney diseases (KCAT) and antibodies binds to KCATs. The present invention provides that KCATs are used as targets for screening agents that modulates the KCAT activities. Further the present invention provides methods for treating diseases associated with kidney.

Подробнее
Номер записи: 69
13-11-2014 дата публикации

Method And System For Identifying A Biomarker Indicative Of Health Condition

Номер: US20140335534A1
Автор: HE Tao, HUANG Shi, LI RUI, LIU JIQUAN, Xu Jian
Принадлежит: The Procter & Gamble Company

By designing a retrogression-progression model in combination with oral microbial community analysis, the present invention provides a method of identifying a biomarker indicative of a subject mammal's condition, wherein the condition is selected from presence of the first disease, severity of the first disease, sensitivity to the first disease, and combinations thereof. The present invention further provides a computer-aided system of identifying a biomarker indicative of a subject mammal's condition. 1. A method of identifying a biomarker indicative of a subject mammal's condition , comprising the steps:a) selecting a first set of test mammals having a first disease;b) obtaining a first oral sample containing a first microbial community from each of the first set of test mammals having the first disease, wherein the first microbial community comprises one or more microbial types;c) treating each of the first set of test mammals having the first disease, who have been first oral sampled, so as to eliminate or reduce the first disease;d) obtaining a second oral sample containing a second microbial community from each of the first set of test mammals who have been treated, wherein the second microbial community comprises one or more microbial types;e) making the first disease reoccur in each of the first set of test mammals who have been second oral sampled;f) obtaining a third oral sample containing a third microbial community from each of the first set of test mammals in whom the first disease has reoccurred, wherein the third microbial community comprises one or more microbial types;g) measuring the first, second and third oral samples to obtain abundances of the one or more microbial types in the first, second and third microbial communities, respectively;h) statistically analyzing the obtained abundances of the one or more microbial types in the first, second and third microbial communities across the first set of test mammals to identify those microbial types ...

Подробнее
Номер записи: 70
09-09-2021 дата публикации

KIDNEY DISEASE TARGETS AND USES THEREOF

Номер: US20210277073A1
Автор: HE Tao, JOSELOFF Elizabeth, RUBEN Steve
Принадлежит:

The present invention provides a method for diagnosing and detecting diseases associated with kidney. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in kidney diseases (KCAT) and antibodies binds to KCATs. The present invention provides that KCATs are used as targets for screening agents that modulates the KCAT activities. Further the present invention provides methods for treating diseases associated with kidney. 1. An isolated protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-2736 and 5165-6044.2. A composition comprising the protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:2737-5164;b) nucleotide sequences that encode a protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-2736 and 5165-6044; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 , or transgenic organism that produces the antibody of .8. The antibody of claim 5 , wherein the antibody is coupled to a composition selected from the group consisting of detectable substances and therapeutic agents.9. A composition comprising the antibody of and a pharmaceutically acceptable carrier.10. An isolated antibody fragment of the antibody of claim 5 , wherein the antibody fragment comprises a fragment selected from the ...

Подробнее
Номер записи: 71
20-11-2014 дата публикации

ELECTRONIC DEVICE WITH SUPPORTING APPARATUS

Номер: US20140340862A1
Автор: DENG LIU-SHA, DENG SONG, HAN HE-TAO, HSIEH YI-TING, LEE GUANG-YAO, LIAO YONG-GAO, LIN YI-SHENG, LO WEN-KANG, TAN JUN-HUA, WAN GUANG-TIAN, XU CHUN-YONG, ZHOU CHANG-SHENG
Принадлежит:

An electronic device includes a main body, an installing assembly, a support, and a connecting assembly. The main body includes a shell and a display screen installed in the shell. The installing assembly is connected to a side of the shell opposite to the display screen. The connecting assembly is rotatably connected between the installing assembly and the support. The support includes a connecting pole and two opposite extending poles perpendicularly extending out from two opposite ends of the connecting pole. The connecting pole and the extending poles cooperatively bound a receiving space. The connecting assembly can be rotated to be received in the receiving space. 1. A supporting apparatus for an electronic device , the supporting apparatus comprising:an installing assembly to be connected to the electronic device;a support comprising a connecting pole and two opposite extending poles extending from two opposite ends of the connecting pole; anda connecting assembly comprising a first end rotatably connected to the installing assembly, and a second end rotatably connected to the support;wherein the connecting pole and the extending poles cooperatively bound a receiving space, the connecting assembly is operable of being rotated to be received in the receiving space.2. The supporting apparatus of claim 1 , wherein the installing assembly comprises a bracket and a mounting plate mounted in the bracket claim 1 , a shaft is rotatably mounted to the mounting plate and is fixed to the electronic device.3. The supporting apparatus of claim 2 , wherein the bracket comprises a supporting plate and a flange protruding outward from a top side and two opposite sides of the supporting plate claim 2 , the supporting plate and the flange cooperatively bound an installation space claim 2 , the mounting plate is received in the installation space and is fixed to the supporting plate.4. The supporting apparatus of claim 3 , wherein the installing assembly further comprises a ...

Подробнее
Номер записи: 72
06-09-2018 дата публикации

COLON DISEASE TARGETS AND USES THEREOF

Номер: US20180251502A1
Автор: DOMON Bruno, HE Tao, LI Aiqun, MCCAFFREY Ian
Принадлежит:

The present invention provides a method for diagnosing and detecting diseases associated with colon. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in colon diseases (CCAT) and antibodies binds to CCAT. The present invention provides that CCAT is used as targets for screening agents that modulates the CCAT activities. Further the present invention provides methods for treating diseases associated with colon. 1. An isolated protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-683 and 1332-1501.2. A composition comprising the protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:684-1331;b) nucleotide sequences that encode a protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-683 and 1332-1501; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 , or transgenic organism that produces the antibody of .8. The antibody of claim 5 , wherein the antibody is coupled to a composition selected from the group consisting of detectable substances and therapeutic agents.9. A composition comprising the antibody of and a pharmaceutically acceptable carrier.10. An isolated antibody fragment of the antibody of claim 5 , wherein the antibody fragment comprises a fragment selected from the group ...

Подробнее
Номер записи: 73
13-09-2018 дата публикации

RUNNING BOARD DEVICE AND VEHICLE HAVING THE SAME

Номер: US20180257572A1
Автор: DU Xinfa, Fan Xing, HE Tao, WANG Yiming, ZHAN Yongyong, ZHANG Qi, Zhou Yuanyuan
Принадлежит: T-MAX (HANGZHOU) TECHNOLOGY CO., LTD

A running board device comprises a stationary running board; a retractable running board apparatus comprising a retractable mechanism moveable between a stretched position and a retracted position and a retractable running board mounted to the retractable mechanism, wherein at the stretched position, at least a part of the retractable running board stretches out below the stationary running board and beyond the stationary running board, and at the retracted position, the retractable running board is retracted into below the stationary running board. 1. A running board device comprising:a stationary running board; anda retractable running board apparatus comprising a retractable mechanism that is moveable between a stretched position and a retracted position and a retractable running board mounted to the retractable mechanism,wherein at the stretched position, at least a part of the retractable running board stretches out below the stationary running board and beyond the stationary running board, and at the retracted position, the retractable running board is retracted into below the stationary running board,wherein the stationary running board is used for stepping and has a flat upper surface,wherein the retractable mechanism comprises:a mounting support;a running board support, wherein the retractable running board is mounted to the running board support; anda limb assembly comprising a first limb, a second limb and a third limb, wherein a first end of the first limb is pivotally connected to the mounting support, a second end of the first limb is pivotally connected to the running board support, a first end of the second limb is pivotally connected to the mounting support, a second end of the second limb is pivotally connected to a first end of the third limb, and a second end of the third limb is pivotally connected to the running board support.2. The running board device as set forth in claim 1 , wherein a groove is disposed in a lower surface of the stationary ...

Подробнее
Номер записи: 74
21-09-2017 дата публикации

CIRCULATING FEEDING PRINTER COMBINING SCREEN PRINTING AND DIGITAL INK JETTING

Номер: US20170266950A1
Автор: HE Tao
Принадлежит: TAOTECH DIGITAL TECHNOLOGY CO., LTD

The invention discloses circulating feeding printer combining screen printing and digital ink jetting, comprising: a rack, the rack includes an upper rack layer and a lower rack layer, the two layers are respectively provided with a transmission platen capable of moving relative to the rack, each transmission platen is provided with a movable printing platen bearing a print medium capable of sliding relative to the transmission platen, a locking device locking the movable printing platen and the transmission platen is arranged between them, platen transfer devices capable of transferring the movable printing platen onto the transmission platen at the different layer are disposed on the rack, separately located at two sides of the transmission platens, the rack is further provided with a screen printer and an inkjet printer used for printing separately. The present invention prints high quality products, occupies small area, has high production efficiency and automation grade.

Подробнее
Номер записи: 75
20-09-2018 дата публикации

METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING DISEASES

Номер: US20180265591A1
Автор: HE Tao, LEE Candy, MOORE Paul, RUBEN Steve, VAN ORDEN Karen
Принадлежит:

Methods and compositions are provided for assessing, treating, and preventing diseases, especially cancer, using cancer-associated targets (CAT). Methods and compositions are also provided for determining or predicting the effectiveness of a treatment for these diseases or for selecting a treatment, using CAT. Methods and compositions are further provided for modulating cell function using CAT. Also provided are compositions that modulate CAT (e.g., antagonists or agonists), such as antibodies, proteins, small molecule compounds, and nucleic acid agents (e.g., RNAi and antisense agents), as well as pharmaceutical compositions thereof. Further provided are methods of screening for agents that modulate CAT, and agents identified by these screening methods. 1. An isolated protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-3 , 7-9 , 13-17 , 23 , 25-33 , 43-44 , 47-48 , 51-52 , 56-59 , 64-67 , and 72-73.2. A composition comprising the protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:4-6, 10-12, 18-22, 24, 34-42, 45-46, 49-50, 53-55, 60-63, 68-71, and 74-75;b) nucleotide sequences that encode a protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-3, 7-9, 13-17, 23, 25-33, 43-44, 47-48, 51-52, 56-59, 64-67, and 72-73; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 ...

Подробнее
Номер записи: 76
18-11-2021 дата публикации

Methods and systems for controlling the agonistic properties of antibody variable domains by light

Номер: US20210355216A1
Автор: Amandine ANASTASIO, Hai-tao HE, Morgane JAEGER, Rémy LASSERRE
Принадлежит: Aix Marseille Universite, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS, Institut National de la Sante et de la Recherche Medicale INSERM

The inventors has developed a recombinant molecular system, named OptoFab, allowing the accurate control of the agonistic properties of an antibody-derived Fab fragment in time and in space using specific wavelengths of light. It consists in a Fab fragment derived from an agonistic antibody of interest, linked to optogenetic modules that confer a light response capacity. Indeed, antibody derived Fab fragments generally keep the specificity of the antibody for its epitope, but not its agonistic properties. However, when Fab fragments are oligomerized, they recover the agonistic properties of the whole antibody. These characteristics, are at the basis of the OptoFab concept as its objective is to manipulate the oligomerization/immobilization statue of a Fab fragment using optogenetics to control its agonistic property. The present invention relates to methods and systems for controlling the agonistic properties of antibody variable domains by light.

Подробнее
Номер записи: 77
03-09-2020 дата публикации

METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING DISEASES

Номер: US20200276329A1
Автор: BIRSE Charles, DOMON Bruno, HE Tao, JOSELOFF Elizabeth, LEE Candy, MCKINNON Katherine, MESRI Mehdi, MOORE Paul, RUBEN Steve, VAN ORDEN Karen
Принадлежит:

Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro. 1. An isolated CAT protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-4 , 9 , 11-12 , 16-19 , 24-36 , 51-59 , 69-74 , 81-85 , 91-102 , 115-116 , 119-121 , 127-134 , 144-145 , 148-149 , 152-159 , 168-174 , and 182-183.2. A composition comprising the CAT protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:5-8, 10, 13-15, 20-23, 37-50, 60-68, 75-80, 86-90, 103-114, 117-118, 122-126, 135-143, 146-147, 150-151, 160-167, 175-181, 184-185;b) nucleotide sequences that encode a CAT protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-4, 9, 11-12, 16-19, 24-36, 51-59, 69-74, 81-85, 91-102, 115-116, 119-121, 127-134, 144-145, 148-149, 152-159, 168-174, and 182-183; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the CAT protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 , or transgenic organism that produces the antibody of .8. The antibody of claim 5 , wherein the antibody is coupled to a composition selected from the group consisting of detectable substances and therapeutic ...

Подробнее
Номер записи: 78
03-09-2020 дата публикации

WINCH, ROPE GUIDE AND TRANSMISSION DEVICE HAVING CLUTCH FUNCTION

Номер: US20200277169A1
Автор: DU Xinfa, HE Tao, WANG Songfeng, WANG Yiming, XU Hongliang, ZHAN Yongyong
Принадлежит:

Disclosed are a winch, a rope guide, and a transmission device having a clutch function. The winch includes a base seat, a reel, a rope guide, a transmission assembly, and a motor. The reel is rotatably provided to the base seat. The rope guide is provided to the base seat. The transmission assembly is connected with the rope guide. The motor is connected with the reel to drive the reel to rotate, and the motor drives the rope guide through the transmission assembly. In the winch according to embodiments of the present disclosure, the rope guide is an active rope guide, bringing about a good rope guiding effect. Moreover, the reel and the rope guide are driven by the same motor, which reduces the number of components and parts, simplifies the structure and control, and lowers costs. 1. A winch , comprising:a base seat;a reel rotatably coupled to the base seat;a rope guide coupled to the base seat;a transmission assembly operably connected with the rope guide; anda motor operably connected with the reel to drive the reel to rotate, and configured to drive the rope guide through the transmission assembly.2. The winch according to claim 1 , further comprising a transmission device claim 1 , wherein the transmission assembly is configured to drive the rope guide through the transmission device claim 1 , wherein the transmission device comprises:a sleeve body connected with the rope guide;a transmission shaft rotatably coupled to the base seat and passing through the sleeve body, and configured to be driven to rotate by the transmission assembly; anda clutch member mounted on the sleeve body and capable of being engaged with and disengaged from the transmission shaft, wherein, when the transmission shaft rotates and is engaged with the clutch member, the clutch member is driven to move the sleeve body in an axial direction of the transmission shaft.3. The winch according to claim 2 , wherein the transmission assembly is configured as a gear transmission device and ...

Подробнее
Номер записи: 79
10-09-2020 дата публикации

SYSTEMS AND METHODS FOR MONITORING A MEDICAL DEVICE

Номер: US20200281557A1
Автор: FAN Zhouyuan, HE Tao, Li Bing, Zhou Jiawen, Zhou Pei
Принадлежит: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.

The present disclosure is related to systems and methods for monitoring a medical device. The medical device may include a tube configured to generate radiation rays and a detector configured to receive radiation rays emitted from the tube. The tube may include an anode target and a filament. The detector may include a plurality of detecting units. The method may include obtaining imaging data acquired by the detector via detecting radiation rays emitted from the tube. The method may also include determining a first feature parameter associated with the radiation rays based on the imaging data. The method may further include monitoring the medical device based on the first feature parameter associated with the radiation rays. 117-. (canceled)18. A system for monitoring a medical device including a tube configured to generate radiation rays , comprising: obtain a vibration acceleration of the tube;', 'determine, based on the vibration acceleration of the tube, a rotation frequency of an anode target configured in the tube; and', 'determine, based on the rotation frequency of the anode target, whether the anode target is malfunctioning., 'a computer-readable storage medium storing executable instructions, and at least one processor in communication with the computer-readable storage medium, when executing the executable instructions, causing the system to1920-. (canceled)21. The system of claim 18 , wherein the vibration acceleration of the tube is provided by a vibration sensor mounted on a shell of the tube.22. The system of claim 18 , wherein to determine claim 18 , based on the vibration acceleration of the tube claim 18 , a rotation frequency of an anode target configured in the tube claim 18 , the at least one processor is further configured to cause the system to:determine spectrum information associated with the rotation frequency of the anode target by performing a transform operation on the vibration acceleration of the tube; anddetermine the rotation ...

Подробнее
Номер записи: 80
29-10-2015 дата публикации

FILM PEELING APPARATUS AND FILM PEELING METHOD

Номер: US20150306864A1
Автор: HE Tao
Принадлежит:

A film peeling apparatus is provided. The film peeling apparatus comprises: a film peeling roller which is sticky; at least one peeling belt which is non-sticky; at least one first rotation shaft which is configured to drive the peeling belt to rotate, wherein when the film peeling roller rotates, the film peeling roller sticks to the film peeling belt and a release film such that the release film is peeled from an original film. 1. A film peeling apparatus , comprising:a film peeling roller which is sticky;at least one peeling belt which is non-sticky;at least one first rotation shaft which is configured to drive the peeling belt to rotate,wherein, when the film peeling roller rotates, the film peeling roller sticks to the film peeling belt and a release film such that the release film is peeled from an original film.2. The film peeling apparatus according to claim 1 , wherein the film peeling apparatus further comprises:at least one supporting shaft configured to allow the peeling belt to rotate about the film peeling roller, the first rotation shaft and the supporting shaft,wherein the supporting shaft has an axis in parallel to that of the first rotation shaft.3. The film peeling apparatus according to claim 2 , wherein the film peeling apparatus further comprises a positioning belt and at least one second rotation shaft claim 2 ,wherein the positioning belt is in contact with the peeling belt, the positioning belt and the peeling belt rotate about the second rotation shaft, the supporting shaft and the film peeling roller, and the positioning belt is configured to limit the movement of the peeling belt in an axis direction of the first rotation shaft,wherein the second rotation shaft has an axis in parallel to that of the first rotation shaft.4. The film peeling apparatus according to claim 3 , wherein the surface of the positioning belt in contact with the peeling belt is provided with at least one groove within which the peeling belt is fixed.5. The film ...

Подробнее
Номер записи: 81
10-09-2020 дата публикации

VEHICLE STEP APPARATUS AND VEHICLE

Номер: US20200282913A1
Автор: DU Xinfa, Fan Xing, HE Tao, Qing Zhaobo, WANG Songfeng, WANG Yiming, Yang Huizhong, ZHAN Yongyong, ZHANG Qi
Принадлежит:

Embodiments of the present disclosure disclose a vehicle step apparatus and a vehicle. The vehicle step apparatus includes a step, a retractable device, and a locking member. The step is movable between an extended position and a retracted position. The retractable device is connected to the step and configured to drive the step to move between the extended position and the retracted position. The locking member is configured to lock the step in the retracted position or to allow the step to move away from the retracted position towards the extended position. 1. A vehicle step apparatus , comprising:a step movable between an extended position and a retracted position;a retractable device connected to the step and configured to drive the step to move between the extended position and the retracted position; anda locking member configured to lock the step in the retracted position or to allow the step to move away from the retracted position towards the extended position.2. The vehicle step apparatus according to claim 1 , wherein the retractable device comprises a mounting bracket claim 1 , a step bracket claim 1 , and an arm assembly claim 1 , the step is mounted on the step bracket claim 1 , and the arm assembly is pivotally connected with the mounting bracket and the step bracket to drive the step to move between the extended position and the retracted position claim 1 ,the locking member is configured to engage with or separate from one of the step and the step bracket, wherein in the retracted position, the locking member engages with the one of the step and the step bracket to lock the step in the retracted position.3. The vehicle step apparatus according to claim 2 , wherein when the step moves from the retracted position towards the extended position claim 2 , the one of the step and the step bracket separates from the locking member against a locking force of the locking member.4. The vehicle step apparatus according to claim 2 , wherein the one of the step ...

Подробнее
Номер записи: 82
11-10-2018 дата публикации

DRIVING CIRCUIT AND LIQUID CRYSTAL DISPLAY DEVICE THEREOF

Номер: US20180293928A1
Автор: Chen Yuyeh, He Jhenwei, HE Tao, Wu Yu
Принадлежит:

A driving circuit and a liquid crystal display device hereof are described. The driving circuit includes a source driving chip to convert the video signal into a plurality of gray scale voltages. A relationship between the brightness and the gray scales of the display panel and a relationship between the brightness and the voltages of the display panel in a predetermined gamma curve are pre-acquired. The source driving chip obtains a string of resistance values based on a relationship between the brightness and the gray scales and a relationship between the brightness and the voltages. The data signal is then generated according to the data control voltage, the first timing control signal, the video signal and the string of resistance values. 1. A driving circuit comprising:a power management chip, configured to generate data control voltages and scanning control voltages;a timing control chip, configured to provide a first timing control signal, a video signal, and a second timing control signal, and to provide a white balance adjustment table for adjusting a data signal according to the white balance adjustment table to optimize a gamma curve;a source driving chip, configured to convert the video signal into a plurality of gray scale voltages and to pre-acquire a relationship between a brightness and gray scales of a display panel and a relationship between the brightness and voltages of the display panel in a predetermined gamma curve, wherein the source driving chip obtains a string of resistance values based on a relationship between the brightness and the gray scales and a relationship between the brightness and the voltages, and the data signal is generated according to the data control voltages, the first timing control signal, the video signal and the string of resistance values so that a display effect of the display panel meets a predetennined requirement; anda gate driving chip, configured to generate a scanning signal according to the scanning control ...

Подробнее
Номер записи: 83
29-10-2015 дата публикации

OXYNITRIDE ORANGE-RED FLUORESCENT SUBSTANCE AND LIGHT-EMITTING FILM OR SHEET AND LIGHT-EMITTING DEVICE COMPRISING THE SAME

Номер: US20150308657A1
Автор: Gao Wei, He Huaqiang, HE Tao, Hu Yunsheng, HUANG Xiaowei, Liu Ronghui, Liu Yuanhong, Zhuang Weidong
Принадлежит:

An oxynitride orange-red fluorescent substance and a light-emitting film or sheet and a light-emitting device comprising the same are disclosed. The chemical formula of the oxynitride orange-red fluorescent substance is MASiNO:dR in which the element M is one or more of the elements Ca, Sr and Ba, the element A is Al or a mixture of Al with one or more of the elements Ga, La, Sc and Y, the element R is one or more of the elements Ce, Eu and Mn, and chemical formula meets 0.8≦m≦1.2, 11.4. The oxynitride orange-red fluorescent substance according to claim 1 , wherein in the powder X-ray diffraction spectrum in which Cuka rays are used claim 1 , a main generation phase of the oxynitride orange-red fluorescent substance at least has a diffraction peak in Bragg angle (2θ) ranges of 31.3-32.7 degrees claim 1 , 35.2-36.2 degrees claim 1 ...

Подробнее
Номер записи: 84
10-09-2020 дата публикации

METHOD AND SYSTEM FOR ASSISTING WITH MATH PROBLEM

Номер: US20200286402A1
Автор: CHEN Mingquan, HE Tao, LUO Huan, Shi Fan
Принадлежит: Hangzhou Dana Technology Inc.

A system and method for assisting with a math problem includes: acquiring an image including at least a first question of the math problem; identifying a first region in the image where the first question is located based on the image; identifying characters in the first region based on the first region so as to obtain the first question; determining a type of the first question based on the first question; if the type of the first question is a calculation question, generating a first answer and a step-by-step problem solving process of the calculation question; and displaying the first question and/or the first region, the first answer and the step-by-step problem solving process. 1. A method for assisting with a math problem comprising:acquiring, by an image capturing device, an image including at least a first question of the math problem;identifying, by a first computing device and a pre-trained first neural network model, a first region in the image where the first question is located based on the image;identifying, by a second computing device and a pre-trained second neural network model, characters in the first region based on the first region, so as to obtain the first question;determining, by a third computing device and a pre-trained third neural network model, a type of the first question based on the first question; generating, by a fourth computing device, a first answer of the calculation question, and generating, by a fifth computing device, a step-by-step problem solving process of the calculation question; and', 'displaying, by a display device, the first question and/or the first region, and displaying, by a display device, the first answer and the step-by-step problem solving process., 'if the type of the first question is a calculation question,'}2. The method according to claim 1 , wherein the generating claim 1 , by the fifth computing device claim 1 , the step-by-step problem solving process comprises:acquiring a corresponding rule from a ...

Подробнее
Номер записи: 85
17-09-2020 дата публикации

ADJUSTMENT DEVICE, ADJUSTOR AND SHOCK ABSORBER

Номер: US20200290424A1
Автор: DU Xinfa, HE Tao, WANG Songfeng, WANG Yiming, XU Hongliang, ZHAN Yongyong
Принадлежит:

An adjustment device includes a body, an adjustment inner gear ring, and an adjustment shaft. The body has a cavity therein, has a first end provided with a first hole and a second hole, and has a peripheral wall provided with a third hole. The first hole, the second hole, and the third hole are connected with the cavity. The adjustment inner gear ring is fitted in the cavity, and has a peripheral wall provided with adjustment holes. The adjustment holes have different cross-sectional areas. A second end of the adjustment shaft has an adjustment gear and passes through the second hole into the cavity. The adjustment gear meshes with the adjustment inner gear ring. The adjustment shaft is rotatable to drive rotation of the adjustment inner gear ring so as to enable the third hole to be connected with the cavity through one of the adjustment holes.

Подробнее
Номер записи: 86
17-09-2020 дата публикации

METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING DISEASES

Номер: US20200291129A1
Автор: HE Tao, LEE Candy, MOORE Paul, RUBEN Steve, VAN ORDEN Karen
Принадлежит:

Methods and compositions are provided for assessing, treating, and preventing diseases, especially cancer, using cancer-associated targets (CAT). Methods and compositions are also provided for determining or predicting the effectiveness of a treatment for these diseases or for selecting a treatment, using CAT. Methods and compositions are further provided for modulating cell function using CAT. Also provided are compositions that modulate CAT (e.g., antagonists or agonists), such as antibodies, proteins, small molecule compounds, and nucleic acid agents (e.g., RNAi and antisense agents), as well as pharmaceutical compositions thereof. Further provided are methods of screening for agents that modulate CAT, and agents identified by these screening methods.

Подробнее
Номер записи: 87
10-11-2016 дата публикации

LIQUID CRYSTAL DISPLAY PANEL AND LIQUID CRYSTAL DISPLAY DEVICE

Номер: US20160329023A1
Автор: Chen Yuyeh, HE Tao, ZHAO Wenqin
Принадлежит:

A liquid crystal display panel is provided by the present invention, which comprises a plurality of data lines, a plurality of scanning lines, and a plurality of pixel units; wherein the pixel units of each column comprise two types of pixel units disposed interleaved, the adjacent pixel units are different types, and each of the data lines connects to the same type of adjacent pixel units. The present invention completes driving a plurality of adjacent row pixel units at the same time by making data lines connect with the same type pixel units. 1. A liquid crystal display panel , comprising:a plurality of data lines, being used to transmit data signals;a plurality of scanning lines, being used to transmit scanning signals; anda plurality of pixel units, being disposed interleaved with the data lines and the scanning lines, wherein the pixel units comprise red pixel units, green pixel units, and blue pixel units, and the pixel units are used to display an image according to the data signals and the scanning signals;wherein the pixel units in each column comprise two types of the pixel units which are disposed in an interleaved manner, the adjacent pixel units are different types, each of the data lines connects to the same type of adjacent pixel units;wherein polarities of the adjacent pixel units are reversed, the adjacent left and right pixel units of each pixel units are different types.2. The liquid crystal display panel according to claim 1 , wherein while the liquid crystal display panel performs 2-D display claim 1 , the scanning lines performs progressive scanning according to rows.3. The liquid crystal display panel according to claim 1 , wherein while the liquid crystal display panel performs 3-D display claim 1 , the scanning lines performs progressive scanning according to scanning-line-groups claim 1 , wherein each of the scanning-line-groups comprises a plurality of the adjacent scanning lines.4. The liquid crystal display panel according to claim 3 , ...

Подробнее
Номер записи: 88
01-10-2020 дата публикации

ANALYSIS METHOD FOR DETERMINING HALOGENS IN GEOLOGICAL SAMPLES BY ICP-MS

Номер: US20200312648A1
Автор: CHEN Haihong, HE Tao, HU Zhaochu, Li Ming, LIU Yongsheng, Zhang Wen
Принадлежит:

The present invention provides an analysis method for determining halogens in geological samples by ICP-MS. The method includes following steps: weighing a geological sample and ammonium bifluoride in a sample dissolving tank, tightening the sample dissolving tank, and shaking; then heating the sample dissolving tank in a drying oven, and setting a temperature of the drying oven as 200-220° C. and heating time as 1-2 hours; cooling the sample dissolving tank to room temperature so as to obtain a solid mixture after heating is ended, adding ammonium hydroxide into the solid mixture, centrifuging, removing a precipitate, and collecting the supernatant; adding an internal standard solution into the supernatant, and uniformly mixing; and optimizing the ICP-MS to an optimal state, testing content of chlorine in the supernatant under a condition of medium resolution m/Δm=4000, and testing content of bromine and iodine in the supernatant under a condition of low resolution m/Δm=300. 1. An analysis method for determining halogens in geological samples by ICP-MS , comprising the following steps:{'b': '1', 'S, weighing a geological sample and ammonium bifluoride and mixing, and heating at 200-220° C. for 1-2 hours;'}{'b': '2', 'S, cooling to room temperature so as to obtain a solid mixture after heating is ended, adding ammonium hydroxide into the solid mixture, centrifuging, removing a precipitate, and collecting the supernatant;'}{'b': 3', '3, 'S, adding an internal standard solution into the supernatant in the step S, and uniformly mixing; and'}{'b': '4', 'S, optimizing the ICP-MS to an optimal state, testing content of chlorine in the supernatant under a condition of medium resolution, and testing content of bromine and iodine in the supernatant under a condition of low resolution.'}21. The analysis method for determining halogens in geological samples by ICP-MS according to claim 1 , wherein in the step S claim 1 , a mass ratio of the geological sample to the ammonium ...

Подробнее
Номер записи: 89
08-11-2018 дата публикации

IMAGE DISPLAYING METHODS AND DISPLAY DEVICES

Номер: US20180322832A1
Автор: He Jhen-Wei, HE Tao, ZHAO Wenqin
Принадлежит: SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD.

The present disclosure includes an image displaying method and a display device. The method includes: obtaining three-color sub-pixel data of each of pixels of a current image, wherein the three-color sub-pixel data includes a first red, green, blue grayscale value (R, G, B) separately; obtaining a first white grayscale value (W) in accordance with the three-color sub-pixel data; performing a color gamut mapping toward the four first grayscale values in accordance with a predetermined rule; performing a sub-pixel rendering process toward the four-color first grayscale values to obtain the updated three-colors sub-pixel data corresponding to each of the pixels; and outputting the updated three-colors sub-pixel data to the display panel. The RGB data of the current image may be converted to the image data that can be displayed on the four-color display panel so as to obtain a vivid display on the four-color display panel. 1. An image displaying method , comprising:{'b': 1', '1', '1, 'obtaining three-color sub-pixel data of each of pixels of a current image, wherein the three-color sub-pixel data comprises a first red grayscale value (R), a first green grayscale value (G), and a first blue grayscale value (B);'}{'b': 1', '1', '1, 'obtaining a white grayscale coefficient according to the first red grayscale value (R), the first green grayscale value (G), and the first blue grayscale value (B);'}{'b': 1', '1', '1', '1, 'obtaining a first white grayscale value (W) in accordance with the white grayscale coefficient and a minimum value selecting from the first red grayscale value (R), the first green grayscale value (G), and the first blue grayscale value (B);'}{'b': 2', '2', '2', '2', '1', '1', '1', '1, 'obtaining a second red grayscale value (R), a second green grayscale value (G), a second blue grayscale value (B), and a second white grayscale value (W) by performing a color gamut mapping toward the first red grayscale value (R), the first green grayscale value (G), the ...

Подробнее
Номер записи: 90
24-11-2016 дата публикации

GRAYSCALE COMPENSATION METHOD

Номер: US20160343283A1
Автор: Chen Yuyeh, HE Tao, Xie Jianjun
Принадлежит:

The present invention provides a grayscale compensation method, the method includes converting raw image data into a first image data; obtaining a second image data which can be displayed on the display panel according to the first image data in a preset manner, and the second image data for each pixel includes 3-color grayscale data among a red, a green, a blue, and a white grayscale data of the first image data; performing a grayscale compensation on the grayscale data of the second image data according to the first image data and a predetermined rule. 1. A grayscale compensation method comprising:converting raw image data into a first image data, the raw image data for each pixel including a raw red grayscale data, a raw green grayscale data, and a raw blue grayscale data, the first image data for each pixel including a first red grayscale data, a first green grayscale data, a first blue grayscale data, and a first white grayscale data;obtaining a second image data which can be displayed on the display panel according to the first image data in a preset manner, the second image data for each pixel including 3-color grayscale data among a red, a green, a blue, and a white grayscale data of the first image data;obtaining a third image data by performing grayscale compensation on the second image data based on the first image data and a predetermined rule, wherein the third image data for each pixel includes 3-color grayscale data among a second red grayscale data, a green grayscale data, a second blue grayscale data, and a second white grayscale data;comparing the third image data with the first image data for each pixel to obtain a missing color data in the third image data for each pixel;obtaining a missing grayscale data for a pixel based on the first image data of the pixel and the missing color data for the pixel, wherein the missing grayscale data represents the grayscale data of the missing color in the third image data of the pixels; andperforming a ...

Подробнее
Номер записи: 91
15-10-2020 дата публикации

COLON DISEASE TARGETS AND USES THEREOF

Номер: US20200325189A1
Автор: DOMON Bruno, HE Tao, LI Aiqun, MCCAFFREY Ian
Принадлежит:

The present invention provides a method for diagnosing and detecting diseases associated with colon. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in colon diseases (CCAT) and antibodies binds to CCAT. The present invention provides that CCAT is used as targets for screening agents that modulates the CCAT activities. Further the present invention provides methods for treating diseases associated with colon. 1. An isolated protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-683 and 1332-1501.2. A composition comprising the protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:684-1331;b) nucleotide sequences that encode a protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-683 and 1332-1501; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 , or transgenic organism that produces the antibody of .8. The antibody of claim 5 , wherein the antibody is coupled to a composition selected from the group consisting of detectable substances and therapeutic agents.9. A composition comprising the antibody of and a pharmaceutically acceptable carrier.10. An isolated antibody fragment of the antibody of claim 5 , wherein the antibody fragment comprises a fragment selected from the group ...

Подробнее
Номер записи: 92
01-12-2016 дата публикации

LIQUID CRYSTAL DISPLAY PANEL AND DEVICE THEREOF

Номер: US20160351136A1
Автор: Chen Yuyeh, HE Tao
Принадлежит:

An LCD panel and an LCD device are provided. The LCD panel includes all pixels respectively defined by a plurality of data lines and a plurality of the scanning lines to form a plurality of pixel columns and a plurality of pixel rows. All of the pixels in each column have the same color, and the two adjacent pixels in each pixel unit have opposite polarities. The pixels having the same color in two adjacent pixel units have opposite polarities, and each of the data lines is connected with the pixels with the same polarity. 1. An LCD panel comprising:a plurality of data lines configured for transmitting data signals;a plurality of scanning lines configured for transmitting scanning signals; anda plurality of pixel units, each of the pixel units including a plurality of pixels, which have colors including red, green, and blue;all of the pixels defined by the data lines forming a plurality of pixel columns, or all of the pixels defined by the scanning lines forming a plurality of pixel rows;wherein all of the pixels in each column have the same color, the pixels with the same color in two adjacent pixel units have opposite polarities, the two adjacent pixels in each pixel unit have opposite polarities, and each of the data lines is connected with the pixels having the same polarity;when the LCD panel performs a two-dimensional display, a progressive scan for the scanning lines is enabled;when the LCD panel performs a three-dimensional display, a sequential scan based on orders of groups for the scanning lines being enabled, in which the group for the scanning lines representing a plurality of adjacent scan lines at the rows numbering 2k or a plurality of adjacent scan lines at the rows numbering 2k+1, where k is a positive integer.2. The LCD panel according to claim 1 , wherein the group of the scanning lines represents 2-4 adjacent scan lines at the rows numbering 2k or 2-4 adjacent scan lines at the rows numbering 2k+1.3. The LCD panel according to claim 1 , wherein ...

Подробнее
Номер записи: 93
22-11-2018 дата публикации

GRAY SCALE VOLTAGE COMPENSATION METHOD OF LIQUID CRYSTAL PANEL, CIRCUIT AND LIQUID CRYSTAL PANEL

Номер: US20180336855A1
Автор: Chen Yu-Yeh, He Jhen-Wei, HE Tao, Wu Yu
Принадлежит: SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD.

Disclosed are a gray scale voltage compensation method of a liquid crystal panel, a circuit for a liquid crystal panel and a liquid crystal panel including the circuit. The invention adjusts the common voltage and/or compensates the pixel voltage to minimize the afterimage of the whole liquid crystal panel under the premise of saving the cost of the liquid crystal panel and greatly improves the panel display performance. 1. A circuit for a liquid crystal panel , wherein the liquid crystal panel comprises:a plurality of gate lines parallel to one another, a plurality of data lines parallel to one another and intersected with the gate lines in a perpendicular and insulated manner, a plurality of thin film transistors located at intersections of the gate lines and the data lines, a plurality of pixel electrodes and a common electrode, the pixel electrodes are coupled to the data lines via the thin film transistors and arranged opposite to the common electrode;the circuit for the liquid crystal panel comprises a driving circuit and a control circuit;the driving circuit drives the liquid crystal panel;the control circuit adjusts a common voltage and/or compensates at least one portion of pixel voltages of at least two different display areas in the liquid crystal panel via the driving circuit to ultimately determine the common voltage and the pixel voltages, the pixel voltage is an alternating inversion voltage of positive and negative polarities such that the pixel voltages of the positive and negative polarities of all the pixels of the at least two different display areas in the liquid crystal panel are symmetrical with respect to the common voltage and maximum pixel voltages of the positive polarity of all the pixels of the at least two different display areas are equal;the driving circuit also outputs the common voltage and the pixel voltages which are ultimately determined.2. The circuit for the liquid crystal panel according to claim 1 , wherein the driving ...

Подробнее
Номер записи: 94
17-12-2015 дата публикации

METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING DISEASES

Номер: US20150361181A1
Автор: HE Tao, LEE Candy, MOORE Paul, RUBEN Steve, VAN ORDEN Karen
Принадлежит:

Methods and compositions are provided for assessing, treating, and preventing diseases, especially cancer, using cancer-associated targets (CAT). Methods and compositions are also provided for determining or predicting the effectiveness of a treatment for these diseases or for selecting a treatment, using CAT. Methods and compositions are further provided for modulating cell function using CAT. Also provided are compositions that modulate CAT (e.g., antagonists or agonists), such as antibodies, proteins, small molecule compounds, and nucleic acid agents (e.g., RNAi and antisense agents), as well as pharmaceutical compositions thereof. Further provided are methods of screening for agents that modulate CAT, and agents identified by these screening methods. 1. An isolated protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-3 , 7-9 , 13-17 , 23 , 25-33 , 43-44 , 47-48 , 51-52 , 56-59 , 64-67 , and 72-73.2. A composition comprising the protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:4-6, 10-12, 18-22, 24, 34-42, 45-46, 49-50, 53-55, 60-63, 68-71, and 74-75;b) nucleotide sequences that encode a protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-3, 7-9, 13-17, 23, 25-33, 43-44, 47-48, 51-52, 56-59, 64-67, and 72-73; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 ...

Подробнее
Номер записи: 95
31-10-2019 дата публикации

SHOCK ABSORBING SCREW FOR CONNECTING HARD DISK TO HARD DISK FRAME

Номер: US20190333543A1
Автор: HAN HE-TAO, LI ZHI-QIANG, LIN YI-SHENG, LIU XIAO-MING, TAN JUN-HUA
Принадлежит:

A shock absorbing screw includes a locking member, a friction member sleeved on the locking member, and a connecting frame sleeved on the friction member. The shock absorbing screw is connected to a hard disk by a connecting portion of the shock absorbing screw. An abutting portion of the shock absorbing screw is connected to the friction member. The connecting portion is passed through a second through hole defined in the friction member. A first end of the connecting frame includes a first clamping portion, a second end of the connecting frame includes a second clamping portion, and a second groove is defined between the first clamping portion and the second clamping portion. The shock absorbing screw is connected to a hard disk frame in the second groove. The friction member is connected to the connecting frame through a first through hole defined in the connecting frame.

Подробнее
Номер записи: 96
07-12-2017 дата публикации

METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING DISEASES

Номер: US20170350897A1
Автор: BIRSE Charles, DOMON Bruno, HE Tao, JOSELOFF Elizabeth, LEE Candy, MCKINNON Katherine, MESRI Mehdi, MOORE Paul, RUBEN Steve, VAN ORDEN Karen
Принадлежит:

Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro. 1. An isolated CAT protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-4 , 9 , 11-12 , 16-19 , 24-36 , 51-59 , 69-74 , 81-85 , 91-102 , 115-116 , 119-121 , 127-134 , 144-145 , 148-149 , 152-159 , 168-174 , and 182-183.2. A composition comprising the CAT protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:5-8, 10, 13-15, 20-23, 37-50, 60-68, 75-80, 86-90, 103-114, 117-118, 122-126, 135-143, 146-147, 150-151, 160-167, 175-181, 184-185;b) nucleotide sequences that encode a CAT protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-4, 9, 11-12, 16-19, 24-36, 51-59, 69-74, 81-85, 91-102, 115-116, 119-121, 127-134, 144-145, 148-149, 152-159, 168-174, and 182-183; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the CAT protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 , or transgenic organism that produces the antibody of .8. The antibody of claim 5 , wherein the antibody is coupled to a composition selected from the group consisting of detectable substances and therapeutic ...

Подробнее
Номер записи: 97
15-12-2016 дата публикации

KIDNEY DISEASE TARGETS AND USES THEREOF

Номер: US20160362461A1
Автор: HE Tao, JOSELOFF Elizabeth, RUBEN Steve
Принадлежит:

The present invention provides a method for diagnosing and detecting diseases associated with kidney. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in kidney diseases (KCAT) and antibodies binds to KCATs. The present invention provides that KCATs are used as targets for screening agents that modulates the KCAT activities. Further the present invention provides methods for treating diseases associated with kidney. 1. An isolated protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS: 1-2736 and 5165-6044.2. A composition comprising the protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS: 2737-5164;b) nucleotide sequences that encode a protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS: 1-2736 and 5165-6044; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 , or transgenic organism that produces the antibody of .8. The antibody of claim 5 , wherein the antibody is coupled to a composition selected from the group consisting of detectable substances and therapeutic agents.9. A composition comprising the antibody of and a pharmaceutically acceptable carrier.10. An isolated antibody fragment of the antibody of claim 5 , wherein the antibody fragment comprises a fragment selected from the ...

Подробнее
Номер записи: 98
14-12-2017 дата публикации

COLON DISEASE TARGETS AND USES THEREOF

Номер: US20170355752A1
Автор: HE Tao, KIM Yeounjin, RUBEN Steve
Принадлежит: CELERA CORPORATION

The present invention provides a method for diagnosing and detecting diseases associated with colon. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in colon diseases (CCAT) and antibodies binds to CCAT. The present invention provides that CCAT is used as targets for screening agents that modulates the CCAT activities. Further the present invention provides methods for treating diseases associated with colon. 1. An isolated protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-1233 and 2228-2638.2. A composition comprising the protein of and a pharmaceutically acceptable carrier.3. An isolated nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:a) SEQ ID NOS:1234-2227;b) nucleotide sequences that encode a protein comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:1-1233 and 2228-2638; andc) nucleotide sequences that are completely complementary to the nucleotide sequences of a) or b).4. An isolated RNAi or antisense nucleic acid molecule that selectively binds to the nucleic acid molecule of .5. An isolated antibody that selectively binds to the protein of .6. The antibody of claim 5 , wherein the antibody is at least one of a monoclonal claim 5 , polyclonal claim 5 , fully human claim 5 , humanized claim 5 , chimeric claim 5 , single-chain claim 5 , or anti-idiotypic antibody.7. A cell line claim 5 , hybridoma claim 5 , phage claim 5 , or transgenic organism that produces the antibody of .8. The antibody of claim 5 , wherein the antibody is coupled to a composition selected from the group consisting of detectable substances and therapeutic agents.9. A composition comprising the antibody of and a pharmaceutically acceptable carrier.10. An isolated antibody fragment of the antibody of claim 5 , wherein the antibody fragment comprises a fragment selected from the group ...

Подробнее
Номер записи: 99
15-12-2016 дата публикации

PIXEL STRUCTURE AND LIQUID CRYSTAL DISPLAY PANEL

Номер: US20160365047A1
Автор: He Jhenwei, HE Tao, ZHAO Wenqin
Принадлежит:

The present invention provides a pixel structure and a liquid crystal display panel. The pixel structure comprises a plurality of pixel units arranged in array, and each pixel unit comprises a white sub pixel (W), a red sub pixel (R), a green sub pixel (G) and a blue sub pixel (B); in respective pixel units, the white sub pixel (W), the red sub pixel (R), the green sub pixel (G) and the blue sub pixel (B) are aligned with the same order along a horizontal direction; a driving mode of the pixel structure is row inversion; as showing an image of the same frame, in pixel units of each column, polarities of sub pixels of every two adjacent columns are opposite; in the sub pixels of every two adjacent columns, polarities of sub pixels of the same color are opposite to make that polarities of every two adjacent sub pixels of the same color in the pixel units of the same row are opposite. It is capable of reducing the horizontal crosstalk of the sub pixels of the same color in the pixel units of the same row to ensure the image display effect. 1. A pixel structure , comprising a plurality of pixel units arranged in array , and each pixel unit comprises a white sub pixel , a red sub pixel , a green sub pixel and a blue sub pixel; in respective pixel units , the white sub pixel , the red sub pixel , the green sub pixel and the blue sub pixel are aligned with the same order along a horizontal direction;a driving mode of the pixel structure is row inversion; as showing an image of the same frame, in pixel units of each column, polarities of sub pixels of every two adjacent columns are opposite; in the sub pixels of every two adjacent columns, polarities of sub pixels of the same color are opposite to make that polarities of every two adjacent sub pixels of the same color in the pixel units of the same row are opposite.2. The pixel structure according to claim 1 , wherein as showing a pure color image of the same frame claim 1 , the polarities of every two adjacent sub pixels ...

Подробнее
Номер записи: 100