Device and Method for Determining Activity of Radiopharmaceutical Material

A detector system measures radioactive material. A fluid path receives at least one aliquot of radiopharmaceutical. The fluid path locates the aliquot within a positioner formed with a concave configuration. A detector is located at an axial distance from the concave surface and determines the level of radioactivity of the aliquot. Alternatively, the fluid path may be less concave and a variable attenuator may be placed between the fluid path and detector. The variable attenuator may have a concavity that is based on the concavity of the fluid path so that the detector's ability to read the radioactivity is optimized. A method for forming an aliquot of radiopharmaceutical in a concave fluid passage. Positioning a detector located a distance from the concave surface to optimize reading spectral energy of the aliquot and activity is determining activity regardless of the position of the aliquot in the passage. 1. A system for measuring radioactive material , comprising:a fluid path for receiving at least one aliquot;an aliquot positioner formed with a concave surface and connected to the fluid path and capable of receiving the at least one aliquot therefrom; anda detector located at an axial distance from the aliquot positioner and operable to determine the level of radioactivity of the at least one aliquot disposed in the aliquot positioner.3. The system of wherein the detector is proximal to a concave side of the aliquot positioner.4. The system of wherein the aliquot positioner includes a passage formed as a coiled claim 1 , spiral or serpentine configuration.5. The system of further including an output assembly connected to an output of the aliquot positioner.6. The system of further including a liquid source of radiopharmaceutical in fluid communication with the fluid path.7. The system of further including at least one optical element disposed between the aliquot positioner and the detector.8. The system of wherein the aliquot positioner has a surface based on a ...

DRIP CHAMBER AND FLUID LEVEL SENSING MECHANISM FOR A FLUID DELIVERY SYSTEM

The fluid injector system includes a source of injection fluid, a pump device, and a fluid path set in fluid connection with the source of injection fluid and the pump device. The fluid path set includes a drip chamber including an elongated body and a raised projection. A fluid level sensing mechanism is operably associated with a fluid control device, and includes a drip chamber support for supporting the drip chamber body and a fluid level sensor associated with the drip chamber support. The drip chamber support is adapted to support the drip chamber body such that the raised projection is in operational contact with the fluid level sensor and the fluid level sensing mechanism is operable to transmit ultrasonic or light energy through the raised projection to be sensed by the fluid level sensor for sensing the injection fluid level in the drip chamber. 1. A fluid delivery system , comprising:a source of injection fluid;a pump device;a fluid control device operably associated with the pump device;a fluid path set in fluid connection with the source of injection fluid and the pump device, the fluid path set comprising a drip chamber comprising an elongated body having a top end, a bottom end and a raised projection provided on the drip chamber body between the top end and the bottom end; and a drip chamber support for supporting the drip chamber body; and', 'a fluid level sensor comprising an ultrasonic or an optical sensor associated with the drip chamber support, the drip chamber support adapted to support the drip chamber body such that the raised projection is in operational contact with the fluid level sensor and the fluid level sensing mechanism is operable to transmit ultrasonic or light energy through the raised projection to be sensed by the fluid level sensor for sensing the injection fluid level in the drip chamber., 'a fluid level sensing mechanism operably associated with the fluid control device, the fluid level sensing mechanism comprising2. The ...

POPPET VALVE ASSEMBLY FOR CONTROLLING A PNEUMATIC ACTUATOR

A poppet valve assembly to control a pneumatic actuator may include a housing having a central bore. A first module may be disposed within the central bore, and the first module may have a first and second poppet valve. A second module may also be disposed within the central bore, and the second module may have a third and fourth poppet valve. A supply of pressurized fluid may be in fluid communication with a plurality of control valves such that pressurized fluid from the control valves opens and closes the poppet valves. The supply of pressurized fluid may also be in fluid communication with the first module and the second module such that the opening and closing of the poppet valves controls the position of the pneumatic actuator. 1. A poppet valve assembly comprising:a valve housing having a central bore;a first module disposed within the central bore, the first module comprising a first normally closed poppet valve and a second normally closed poppet valve, wherein each of the first and second normally closed poppet valves has an open position and a closed position;a central port formed in the first module, wherein the central port of the first module is adapted to be coupled to a first volume of a pneumatic cylinder;an exhaust port formed in the first module such that the central port is in fluid communication with the exhaust port when the first poppet valve is in the open position; anda supply port formed in the first module such that the central port is in fluid communication with the supply port when second poppet valve is in the open position,wherein the supply port is configured to be in fluid communication with a supply of pressurized fluid such that when the second poppet valve is in the open position, pressurized fluid is provided to the first volume of the pneumatic cylinder, andwherein the exhaust port is configured to vent pressurized fluid from the first volume of the pneumatic cylinder when the first poppet valve is in the open position.2. The ...

Flow Based Pressure Isolation Mechanism for a Fluid Delivery System

The fluid delivery system includes a pressurizing device for delivering a pressurized injection fluid, a low pressure fluid delivery system, and a pressure isolation mechanism adapted for fluid communication with the pressurizing device and low pressure fluid delivery system. The pressure isolation mechanism includes a housing defining an inlet port, an isolation port, and an internal cavity. The housing defines a seal seat in the internal cavity between the inlet port and isolation port. A valve member is disposed in the internal cavity. The valve member is free floating in the internal cavity and is adapted to engage the seal seat. The valve member has an open position permitting fluid communication between the inlet port and isolation port, and is fluid flow responsive to fluid flow in the inlet port to engage the seal seat and attain a closed position preventing fluid flow between the inlet port and isolation port. 1. A fluid delivery system with flow-based pressure isolation , comprising:a pressurizing device for delivering injection fluid under pressure;a low pressure fluid delivery system; and a housing body defining an inlet port, an isolation port, a lumen in fluid communication with the isolation port, and an internal cavity, the housing body further defining a seal seat in the internal cavity between the inlet port and the isolation port;', 'a valve member disposed in and free floating in the internal cavity and adapted to engage the seal seat, the valve member comprising an open position permitting fluid communication between the inlet port and the isolation port, and wherein the valve member is fluid flow responsive to fluid flow in the inlet port to engage the seal seat and attain a closed position preventing fluid flow between the inlet port and the isolation port;', 'a resiliently deformable flow initiating mechanism disposed in the lumen and in fluid communication with the isolation port, the flow initiating mechanism providing upstream capacitance ...

VALVE SIGNATURE DIAGNOSIS AND LEAK TEST DEVICE

A valve signature diagnosis and leak testing device includes a spool valve operatively connected to a pilot valve, the pilot valve being configured to position the spool valve to one of an open position and a closed position. A blocker valve is fluidly connected to a control fluid outlet of the spool valve. An electrical module is operatively connected to the pilot valve, a supply of control fluid, and the blocker valve, the electrical module being capable of sending pulsed electrical signals to the pilot valve and the blocker valve to selectively position the spool valve and the blocker valve to an open or closed position. 1. A valve signature diagnosis and leak testing device for a control valve , the valve signature diagnosis and leak testing device comprising:a spool valve operatively connected to a pilot valve, the pilot valve being configured to position the spool valve to one of an open position and a closed position, the spool valve including a first control fluid inlet, a first control fluid outlet, and a second control fluid outlet, the first control fluid inlet being fluidly connected to a supply of control fluid and the first control fluid outlet being configured to be connected to a valve actuator;a blocker valve fluidly connected to the second control fluid outlet; andan electrical module operatively connected to the pilot valve, the supply of control fluid, and the blocker valve, the electrical module being capable of sending pulsed electrical signals to the pilot valve and the blocker valve to selectively position the spool valve and the blocker valve to an open or a closed position,wherein the open position of the spool valve fluidly connects the first control fluid inlet to the first control fluid outlet and the closed position of the spool valve fluidly connects the first control fluid outlet to the second control fluid outlet.2. The valve signature diagnosis and leak testing device of claim 1 , wherein the electrical module includes a main ...

WIRELESS MONITORING AND CONTROL OF SAFETY STATIONS IN A PROCESS PLANT

A safety station for use in a process plant includes one or more leverless limit switches to detect activation of one or more parts of the safety station. The safety station further includes a wireless transmitter coupled to the leverless limit switches to transmit signals associated with the safety station to a base station device, which is communicatively coupled to one or more control and/or monitoring devices. 1. A safety station for use in a process plant , the safety station comprising:one or more leverless limit switches to detect activation of one or more parts of the safety station; anda wireless transmitter coupled to the leverless limit switches to transmit signals associated with the safety station to a base station device, wherein the base station device is communicatively coupled to one or more control and/or monitoring modules.2. The safety station of claim 1 , wherein the leverless limit switch is a GO® switch manufactured by the TopWorx corporation.3. The safety station of claim 1 , wherein the leverless limit switch remains latched until physically reset.4702. The safety station of claim 1 , wherein the wireless transmitter is the Rosemount dual input transmitter manufactured by the Emerson corporation.5. The safety station of claim 1 , wherein the wireless transmitter is an intrinsically safe wireless transmitter.6. The safety station of claim 1 , wherein the safety station is a safety shower and/or an eye wash station.7. The safety station of claim 1 , wherein at least one of the one or more control and/or monitoring stations is a remote touch screen panel.8. The safety station of claim 1 , wherein at least one of the one or more control and/or monitoring stations is a paperless recorder.9. The safety station of claim 1 , wherein at least one of the one or more control and/or monitoring stations is a workstation.10. A safety station monitoring and control system in a process plant claim 1 , the system comprising:one or more safety stations ...

SWITCH MODULE

A switch module used for position sensing may be operated in a number of modes for compatibility with a number of legacy position sensing products. A dry switch circuit can be configured to provide a direct output, emulating dry reed, high-side or low-side switched configurations. Alternatively, the dry switch circuit can be connected to an input of a NAMUR circuit to provide the known current output for that standard. In another configuration the dry switch can be selectively coupled to one of two NAMUR circuits allowing the switch module to provide a low-to-high current NAMUR output or a high-to-low current NAMUR output. 1. A switch module arranged and adapted to report a position of a moveable element external to the switch module , the switch module comprising:a first external connection, a second external connection, and a third external connection;a dry contact relay having a relay contact position responsive to a position of a component external to the switch module, the dry contact relay having a common connection, a normally open connection and a normally closed connection, where the normally open connection corresponds to a first position of the moveable element and the normally closed connection corresponding to a second position of the moveable;a NAMUR circuit having a first input connection pair and a first output connection pair;an electrical connection from the normally open connection of the dry relay to a first input of the first input connection pair of the NAMUR circuit;a selector operable to connect the common connection of the dry contact relay to i) a null contact of the selector or ii) a second input of the first input connection pair of the NAMUR circuit;a second electrical connection from the first output of the NAMUR circuit to one of the first external connection or the second external connection; anda third electrical connection between the second output of the NAMUR circuit to the third external connection;a first jumper that removeably ...

FLUID PATH CONNECTORS AND CONTAINER SPIKES FOR FLUID DELIVERY

A fluid connector includes an extending section including a spiked end to pierce the container port. The extending section includes at least one air conduit and at least one fluid conduit therethrough. The extending section further includes a first abutment member and second abutment member. The first abutment member is adapted to abut a first or air side of the container port upon piercing of the container port. The second abutment member is spaced from the first abutment member and is adapted to abut a second or fluid sided of the container port. The fluid connector can further include grasping members extending from the extending section to facilitate rotation of the extending section relative to the container port during piercing thereof. The fluid connector can also include a check valve in fluid connection with the air line. In several embodiments, the check valve is positioned within the extending section. 120-. (canceled)21. A system for administering a fluid at a high flow rate to a patient , the system comprising:(a) a source of pressurized gas; and(b) a fluid connector for connection to a container of the fluid, the fluid connector having (i) an air vent that is connectible to the source of pressurized gas and (ii) a fluid line that is connectible to a fluid path through which the fluid in the container can be administered to the patient;wherein, when the fluid connector is connected to the container and the air vent is connected to the source of pressurized gas, the gas from the source of pressurized gas flows into the air vent to pressurize the container and thus forcibly expels the fluid therein through the fluid line and the fluid path and into the patient.22. The system of wherein the source of pressurized gas includes a compressor from which the gas pressurized therein is provided to the air vent so as to pressurize the container and thus forcibly expel the fluid therein through the fluid line.23. The system of wherein the source of pressurized gas ...

Catheters and Related Equipment

A device for inserting a catheter into a blood vessel that uses fluid flow to aid the insertion of the catheter into a patient is described herein. The device includes a catheter retention device that houses a catheter and is configured to attach to an angiocatheter or other blood vessel access device. The catheter retention device receives fluid and guides the catheter into the blood vessel using the flow of fluid to carry the catheter into the blood vessel. 1. A catheter retention device comprising:a catheter retention body having a proximal and a distal end, the catheter retention body defining a lumen designed and configured to receive a catheter;at least one distal lateral fitting on a distal portion of the catheter retention body, the lateral fitting being designed and configured to couple to a fluid source and introduce fluid into the distal portion of the lumen of the catheter retention body; anda distal fitting at a distal end of the catheter retention body, the distal fitting defining an aperture through which fluid and a catheter exit the lumen of the catheter retention body, wherein fluid flowing through the aperture provides substantially all of the force required to expel the catheter from the catheter retention body.2. The catheter retention device of claim 1 , further comprising a catheter contained within the lumen of the catheter retention body.3. The catheter retention device of claim 2 , wherein the catheter is wound claim 2 , coiled claim 2 , or folded in the lumen of the catheter retention body.4. The catheter retention device of claim 2 , wherein the catheter is composed of a soft flexible material.5. The catheter retention device of claim 2 , wherein the catheter does not include a guidewire.6. The catheter retention device of claim 1 , further comprising one or more proximal fitting operably connected to the catheter and defining an aperture through the catheter retention body.7. The catheter retention device of claim 1 , further comprising ...

Modeling of pharmaceutical propagation

A method of delivering a contrast enhancing fluid to a patient using an injector system, including: determining at least one patient transfer function for the patient based upon data specific to the patient, the at least one patient transfer function providing a time enhancement output for a given input; determining a desired time enhancement output; using the at least one patient transfer function to determine an injection procedure input; and controlling the injector system at least in part on the basis of the determined injection procedure input.

Peristaltic pump assemblies and systems incorporating such pump assemblies

Peristaltic pump assemblies in which the closing and opening of a pivoting or sliding door is coordinated with movement of the occlusion bed toward and away from the rotor assembly to engage and disengage tubing within the occlusion pathway are disclosed. Linkage mechanisms provided by the interaction of cam surfaces with rollers, as well as bar linkage mechanisms, are disclosed. The linkage mechanism, in addition to providing precise displacement of the occlusion bed, may also provide an over-center feature that enhances safety and pump operation when the door is in a closed position. Latching mechanisms and sensors may be incorporated. Adaptive components such as tubing cassettes routing aspiration and/or infusion tubing in a predetermined configuration to mate with occlusion pathways in aspiration and/or infusion pump assemblies provided in various types of medical devices and control consoles are also provided.

Radiopharmaceutical Concentration Measurement System and Method

The system for measuring the radioactive concentration of a radiopharmaceutical includes a container, an interrogation region, a radiation detector, a signal capture device and microprocessor system. The interrogation region associated with the container. The radiation detector to focus detecting radiation emitted from the interrogation region. The signal capture device capable of obtaining a radiation measurement of the interrogation region. The microprocessor system in data communication with the signal capture device. The microprocessor system is capable of calculating a radioactive concentration of a radiopharmaceutical emitting radiation contained in the interrogation region from the signal capture device. 1. A system for measuring the radioactive concentration of a radiopharmaceutical , comprising:a container;an interrogation region associated with the container;a radiation detector to focus radiation emitted from the interrogation region;a signal capture device capable of obtaining a radiation measurement of the interrogation region; anda microprocessor system in data communication with the signal capture device,wherein the microprocessor system is capable of calculating a radioactive concentration of a radiopharmaceutical emitting radiation contained in the interrogation region from the signal capture device.2. The system of wherein the microprocessor system is capable of calculating an identity of a radioactive nuclide associated with a radiopharmaceutical emitting radiation contained in the at least interrogation region from signal capture output.3. The system of further including an aperture system having at least one optical element disposed between the interrogation region and the radiation detector claim 1 ,wherein the radioactive concentration of a radioactive nuclide in the interrogation region is provided to the aperture system to control a selection of the at least one optical element.4. The system of further including a collimator disposed ...

INTERVENTIONAL CATHETER ASSEMBLIES, CONTROL CONSOLES AND ADAPTIVE TUBING CASSETTES

Interventional catheter assemblies, operating systems and adaptive interface components allow operation of a variety of interventional catheter assemblies, including infusion catheters, aspiration catheters and interventional catheters that provide both infusion and aspiration, using a common control console housing infusion and aspiration systems. Adaptive tubing cassettes having a handle and one or more preformed tubing loops route aspiration and/or infusion tubing in a predetermined configuration to mate with aspiration and infusion systems on a control console. 1. An adaptive tubing cassette for use in connection with an interventional catheter assembly and a control console , comprising: a handle component having an interface region adapted to mount stably in a mating interface region of a control console and two preformed tubing loops mounted to and extending from the handle component , the preformed tubing loops each having different dimensions and different tubing properties.2. The adaptive tubing cassette of claim 1 , wherein each of the preformed tubing loops forms a U-shaped loop.3. The adaptive tubing cassette of claim 1 , wherein the preformed tubing loops extend from the handle component in the same direction in a side-by-side arrangement.4. The adaptive tubing cassette of claim 1 , wherein a first preformed tubing loop comprises a thicker walled tubing material than that of a second preformed tubing loop.5. The adaptive tubing cassette of claim 1 , wherein a first preformed tubing loop comprises a stiffer tubing material than that of a second preformed tubing loop.6. The adaptive tubing cassette of claim 1 , wherein a first preformed tubing loop has a larger outer diameter than that of a second preformed tubing loop.7. The adaptive tubing cassette of claim 1 , wherein a first preformed tubing loop extends a greater distance from an edge of the handle component than a second preformed tubing loop.8. The adaptive tubing cassette of claim 1 , wherein the ...

Rapid exchange fluid jet catheter and method

Catheters including guidewire tubes having a limited length and methods of using the catheters are described. The catheters may be delivered over guidewires in procedures that are commonly referred to as rapid-exchange delivery. In some embodiments, the catheters may be miniature flexible thrombectomy catheters that may be used to remove thrombus or other unwanted material from a body blood vessel or other small regions of body cavities in which the distal portion of the catheter has smaller external dimensions than the larger proximal portion

Infusion Flow System and Fluid Coupling

Fluid infusion systems and fluid couplings are described herein. The infusion systems may include one or more fluid couplings used to make fluidic connection between a supply line and delivery tubing. The fluid couplings separate the functions of providing a seal around a delivery tube and retaining the delivery tube within the fluid coupling. The seal provided around the delivery tube prevents leakage around an exterior surface of a delivery tube such that fluid passing through the coupling must pass through the delivery tube rather than leak around the delivery tube. The structure used to retain the delivery tube in the fluid coupling prevents ejection of the delivery tube from the coupling due to the fluid pressures present in the coupling. The separate functions are performed by different structures within the fluid couplings. 1. A fluid coupling apparatus comprising: a primary bore comprising an opening facing the distal end of the housing and a proximal face located within the bore, the proximal face facing the distal end of the housing, and', 'a supply line passage formed in the housing, the supply line passage extending from the proximal end of the housing to an opening in the proximal face of the primary bore;, 'a housing comprising a proximal end, a distal end, and a longitudinal axis extending between the proximal end and the distal end of the housing, wherein the housing further comprises a seal end facing the proximal face of the primary bore,', 'a collet bore comprising a collet compression surface at a proximal end and an opening at a distal end, and', 'a sleeve passage extending from the proximal end of the sleeve into the collet bore;, 'a sleeve comprising a proximal end located in the primary bore, wherein the sleeve further comprises a plurality of collet fingers surrounding a collet passage, wherein each of the collet fingers comprises an inclined surface proximate the proximal end of the collet,', 'wherein the inclined surfaces of the plurality ...

Systems and Methods of Delivering a Dilated Slurry to a Patient

A system for delivering a slurry to a patient includes a fluid, a material that is non-dissolvable or immiscible in the fluid, thereby forming a slurry, a container adapted to contain the slurry and a supernate of the slurry, the container defining an outlet through which the slurry is delivered to the patient, a fluidizing system associated with the container, a pressurizing mechanism adapted to create a pressure to cause the slurry contained within the container to flow for delivery to the patient and a control unit in communication with and adapted to control the fluidizing system and the pressurizing mechanism. The fluidizing system is adapted to effect dilation of the slurry while maintaining at least a portion of the supernate.

Catheter having tapered guide surface

A catheter assembly includes a catheter body having a catheter lumen. A manifold assembly is coupled with a proximal catheter portion. A manifold lumen extends through the manifold assembly, and the manifold lumen includes an assembly cavity extending around the proximal catheter portion. A fluid jet loop is coupled with a high pressure tube at a distal catheter portion. The catheter assembly further includes a tapered loop guide surface.

MODELING OF PHARMACEUTICAL PROPAGATION AND PARAMETER GENERATION FOR INJECTION PROTOCOLS

A system includes a parameter generation system to determine at least one parameter for an injection procedure (for example, a parameter of an injection protocol or an imaging system parameter), the parameter generator system includes a physiologically based pharmacokinetic model to model propagation of a contrast medium injected into a patient including at least one of a non-linear saturation term in a peripheral venous compartment, at least one configurable transport delay term through at least one compartment, or an adaptation to model volumetric flow rate of blood and an effect thereof on the propagation of contrast medium after injection of contrast medium ceases. The physiologically based pharmacokinetic model can, for example, be discretizable.

BLADDER SYRINGE FLUID DELIVERY SYSTEM

A bladder syringe for a fluid delivery system includes a cylindrical body, a cap-bladder assembly, a plunger element disposed in the cylindrical body, and a mounting assembly to secure the cap-bladder assembly to the cylindrical body. The cylindrical body has a distal end and a proximal end and defines a throughbore. The cap-bladder assembly is adapted for connection to the distal end of the cylindrical body, and includes a cap body and a bladder. The cap body defines an interior cavity and a distal discharge conduit and is adapted to engage the distal end of the cylindrical body. A disc-shaped bladder is disposed within the interior cavity and typically includes a central membrane portion. The plunger element is disposed in the throughbore of the cylindrical body and is vented to enable evacuation of the space between the plunger element and the cap-bladder assembly in the cylindrical body. 1. A bladder syringe for a fluid delivery system , comprising:a cylindrical body having a distal end and a proximal end and defining a throughbore; a cap comprising a cap body defining an interior cavity and a distal discharge conduit, the cap body seated on the distal end of the cylindrical body; and', 'a disc-shaped bladder disposed within the interior cavity and comprising a membrane portion; and, 'a cap-bladder assembly adapted for connection to the distal end of the cylindrical body, comprisinga plunger element disposed in the throughbore of the cylindrical body.2. A bladder syringe as claimed in claim 1 , further comprising a retainer ring to secure the bladder in the interior cavity of the cap body.3. A bladder syringe as claimed in wherein the membrane portion has extra material in a central area of the membrane portion.4. A bladder syringe as claimed in wherein the membrane portion defines a convoluted central well portion.5. A bladder syringe as claimed in wherein the membrane portion is substantially planar.6. A bladder syringe as claimed in wherein the membrane ...

INJECTOR SYSTEM FOR ENCODING AND SENSING OF SYRINGE INFORMATION

A syringe for use with a powered injector to inject a fluid into a patient includes at least a first indicator positioned on the syringe at a predetermined axial position. The distance between a rearward surface of the first indicator and a predetermined position on the powered injector provides information about the syringe configuration. The first indicator can, for example, be a rear surface of the attachment flange. An injector system includes a powered injector having a drive member and at least one sensor for detecting energy. The injector system also includes a syringe having at least a first indicator positioned on the syringe at a predetermined axial position. The energy detected by the sensor is determined by the axial position of the indicator when the syringe is attached to the powered injector. The axial position of the indicator thereby provides information about the syringe configuration. 1. An injector system comprising: a powered injector comprising a drive member and at least one sensor for detecting energy; and a syringe comprising at least a first indicator positioned on the syringe at a predetermined position , the syringe configuration that is detected by the sensor is determined by the position of the at least a first indicator when the syringe is attached to the powered injector , the position of the at least a first indicator thereby providing information about the syringe configuration.2. The injector system of wherein a rear surface of the first indicator transmits energy to the sensor.3. The injector system of wherein the rear surface of the first indicator comprises an energy source to transmit energy to the sensor.4. The injector system of wherein the rear surface of the first indicator comprises a surface that transmits energy to the sensor by reflecting energy from an energy source to the sensor.5. The injector system of wherein the powered injector further comprises a contact member movably disposed in the injector claim 1 , a ...

FLUID DELIVERY SYSTEMS, DEVICES AND METHODS FOR DELIVERY OF HAZARDOUS FLUIDS

A system for delivering fluid to a patient includes a container suitable for holding a fluid and an enclosure to shield the fluid. The system further includes a pump device capable of pumping fluid from the container and delivering the fluid to the patient, and the container adapted to be attachable to the pump device. 1. A system for delivering a fluid to a patient comprising:a container suitable for holding a fluid and comprising an enclosure to shield the fluid; anda pump device capable of pumping the fluid from the container and delivering the fluid to the patient;wherein the container is adapted to be attachable to the pump device.2. The system of wherein the fluid comprises a radiopharmaceutical fluid and the enclosure is radiation shielded.3. The system of wherein the container comprises a heating/cooling element for heating/cooling the fluid.4. The system of wherein the container is removably attached to the pump device via a release latch.5. The system of wherein the pump device comprises controls positioned on the body of the pump device to control operation of the pump device.6. The system of further comprising a remote control device associated with the pump device to control operation of the pump device.7. The system of wherein the container is disposable.8. The system of further comprising a second container removably attachable to the pump device and containing a different fluid from the fluid.9. The system of wherein the fluid comprises a pharmaceutical fluid and the different fluid comprises a diluent fluid.10. The system of further comprising a mixing device associated with the pump device for mixing the fluid and the different fluid for delivering a fluid mixture of the fluid and the different fluid to the patient.11. The system of wherein the mixing device comprises a sterile tubing set for mixing the fluid and the different fluid.12. The system of wherein the pump device is manually operated.13. The system of wherein the container is adapted to ...

HIGH PRESSURE SENSOR FOR USE WITH A FLUID DELIVERY SYSTEM

A pressure sensor for use with a fluid delivery system having good sensitivity at low pressure, but also configured to remain in operating condition after being exposed to high pressures is disclosed herein. In one variation, the pressure sensor includes a fluid path set, a deformable element associated with the fluid path set and configured to deform in response to an external pressure, and a pressure transducer for monitoring deformation of the deformable element. In certain embodiments, the pressure sensor is configured to measure fluid pressure within the range of between about 0 mm Hg to about 300 mm Hg. However, the sensor pressure is also be configured to remain functional after being exposed to pressure in excess of about 60,000 mm Hg. 1. A hemodynamic pressure sensor for use with a fluid delivery system comprising:a fluid path defined by a tubing element;a pressure transducer in continuous fluid communication with fluid in the tubing element and adapted to measure fluid pressure in the tubing element, the pressure transducer comprising a deformable element configured to deform in response to changing fluid pressure in the tubing element, andwherein the pressure transducer converts to an electronic signal a representation of the amount of deformation of the deformable element to measure the changing fluid pressure in the tubing element.2. The hemodynamic pressure sensor of claim 1 , wherein the pressure transducer is configured to measure pressure within the range of between about 0 mm Hg to about 300 mm Hg and wherein the pressure transducer is configured such that it remains in working condition after being exposed to pressure in excess of about 60 claim 1 ,000 mm Hg.3. The hemodynamic pressure sensor of claim 1 , wherein the pressure transducer is configured to be placed in fluid connection with a pressure port in fluid communication with the tubing element.4. The hemodynamic pressure sensor of claim 1 , wherein the pressure transducer is an optical ...

Bellows Syringe Fluid Delivery System

A bellows assembly for a fluid delivery system is a multi-component device that includes a cylindrical pressure jacket and a bellows syringe that is received within the pressure jacket. The bellows syringe includes a cap member and a bellows member. The bellows syringe in one embodiment is adapted to be secured to the pressure jacket by the cap member. The cap member is formed with a discharge port, which may be formed as conventional luer fitting. The discharge port is disposed coaxially within an annular wall on the outward facing side of the cap member and may be recessed within the annular wall. The bellows member is a hollow body that includes a series of bellows sections or rings. A distal end of the bellow member is formed with a discharge neck terminating in a discharge port, and the proximal end is formed with a closed end wall. 1. A bellows syringe for a fluid delivery system , comprising:a cap member defining an internal cavity and a discharge port, the cap member further comprising a depending skirt portion; anda bellows member disposed in the internal cavity and held in a compressed state in the internal cavity by engagement between the cap member and a proximal end of the bellows member.2. A bellows syringe as claimed in claim 1 , wherein the skirt portion comprises a plurality of radially-inward extending tab members engaged with the proximal end of the bellows member to hold the bellows member in the compressed state in the internal cavity.3. A bellows syringe as claimed in claim 1 , wherein the proximal end of the bellows member is closed and a distal end of the bellows member defines a discharge port in fluid communication with the cap member discharge port claim 1 , and wherein the closed proximal end of the bellows member comprises at least one attachment member for attaching the bellows member to a piston head of a piston element.4. A bellows syringe as claimed in claim 3 , wherein the at least one attachment member is disposed in an end pocket ...

THROMBECTOMY CATHETER DEPLOYMENT SYSTEM

A thrombectomy catheter deployment for operation of a thrombectomy catheter includes a stand alone drive unit and a disposable pump/catheter assembly which is manually placed into a carriage assembly in the drive unit. The pump/catheter assembly has a plurality of preconnected components including tubular structure and a thrombectomy catheter connected thereto and is transported into or out of the interior of the drive unit for automatic high pressure pump piston head engagement or disengagement with a reciprocating linear actuator and for automatic engagement of disengagement of an effluent waste tube with a roller pump. A barcode reader senses specific operational data pertaining to an individual pump and provides an interface for operation of the reciprocating linear actuator. 1. A pump and catheter assembly for use with a drive unit comprising: a catheter, and', 'an infusion pump in communication with the catheter, the infusion pump including a piston having a piston head, the piston head is configured for coupling with a pump connector of a drive unit, the drive unit configured to reciprocate the piston;, 'a preconnected and consolidated pump and catheter assembly includingwherein the infusion pump and catheter are in communication prior to loading within the drive unit; andwherein the consolidated pump and catheter assembly includes one or more digital instructions for the drive unit.2. The pump and catheter assembly of claim 1 , wherein the preconnected and consolidated pump and catheter assembly includes a connection manifold assembly including:an infusion inlet port configured for communication with a source of infusion fluid,an infusion outlet port in communication with an infusion lumen of the catheter, andan infusion path in communication with the infusion pump and the infusion inlet and outlet ports.3. The pump and catheter assembly of claim 2 , wherein the infusion path includes a bubble trap.4. The pump and catheter assembly of claim 2 , wherein the ...

RADIOPHARMACEUTICAL DELIVERY DEVICE

A device for delivery of a radiopharmaceutical and, in some embodiments, delivery of a pharmaceutical agent are provided herein. 1. A fluid path set comprising:a confluence valve;a four-way valve;a first tubing section in fluid communication with a first input and the confluence valve;a second tubing section in fluid communication with a second input and the confluence valve;a third tubing section in fluid communication with the confluence valve and the four-way valve;an output tubing section in fluid communication with the four-way valve and at least one output fitting;a waste tubing section in fluid communication with the four-way valve and at least one waste receptacle; andan auxiliary tubing section in fluid communication with the four-way valve and the confluence valve.2. The fluid path set of claim 1 , further comprising a coil assembly disposed between the confluence valve and the four way valve in fluid communication with at least the third tubing section.3. The fluid path set of claim 1 , further comprising a medical fluid storage container coupled to the first input.4. The fluid path set of claim 3 , wherein the medical fluid storage container comprises a cylindrical device having a plunger slidably inserted into the fluid storage container creating a seal.5. The fluid path set of claim 3 , further comprising a connector configured to connect to a fluid reservoir in fluid communication with the fluid storage container.6. The fluid path set of claim 1 , wherein the second input comprises a vial spike.7. The fluid path set of claim 1 , further comprising a pharmaceutical delivery port in fluid communication with the output tubing section.8. The fluid path set of claim 1 , wherein the at least one waste receptacle comprises an IV bag.9. The fluid path set of claim 1 , further comprising joints claim 1 , linear joints claim 1 , T-joints claim 1 , 4-way joints claim 1 , valves claim 1 , check valves claim 1 , by-pass valves claim 1 , stop cocks claim 1 , ...

RADIOPHARMACEUTICAL DELIVERY AND TUBE MANAGEMENT SYSTEM

A device for delivery of a radiopharmaceutical and, in some embodiments, delivery of a pharmaceutical agent are described herein. Various other components for delivery systems including tubing management systems, primer caps, diffusion chambers, radiation shields and syringe shields, and other devices and methods are also described. 1. A tubing management system comprising:a tubing channel;a shield plate covering the tubing channel;at least one pulley positioned to move forward and aft within the tubing channel;a spindle extending through the pulley;a handle disposed on an end of the spindle extending through the shield plate; anda slide contacting the spindle opposite the handle; anda track having an upper channel and a lower channel configured to accept the slide.2. The tubing management system of claim 1 , wherein the pulley further comprises a circumferential groove.3. The tubing management system of claim 2 , wherein the circumferential groove comprises a large side wall and a short side wall opposite the large side wall and wherein the short side wall faces the shield plate.4. The tubing management system of claim 1 , wherein the shield plate further comprises a pulley channel extending to an edge of the shield plate.5. The tubing management system of claim 4 , further comprising a secondary tubing channel extending from an edge of the shield plate to the pulley channel.6. The tubing management system of claim 5 , further comprising a retractor slot extending from the secondary tubing channel.7. The tubing management system of claim 5 , further comprising a pulley groove in cooperation with the pulley channel.8. The tubing management system of claim 1 , further comprising an upper shielded spacer and a lower shielded spacer operably connected to the shield plate.9. The tubing management system of claim 1 , wherein the system is configured and arranged to attach to an injector body.10. A primer cap comprising: a nut designed and configured to be grasped by a ...

RADIATION SHIELD ADAPTERS

A syringe shield used for containing radioactive drugs in order to reduce healthcare provider's exposure to radiation or to reduce or eliminate ambient light contamination to optically sensitive components in a syringe. 1. A syringe shield comprising:a first shield panel having a syringe bore designed and configured to correspond to the shape of a syringe; anda second shield panel having a syringe bore designed and configured to correspond to the shape of a syringe;wherein reversible coupling of the first shield panel and the second shield panel provides a syringe bore configured to encase a syringe and provide a plunger access bore configured to allow access to a plunger associated with the syringe.2. The syringe shield of claim 1 , wherein the first shield panel and the second shield panel are hingedly attached.3. The syringe shield of claim 1 , further first shield panel and the second shield panel comprise a radioactive emissions blocking material.4. The syringe shield of claim 3 , wherein a syringe is completely or nearly completely encased by the radioactive emissions blocking material when the first shield panel and the second shield panel are coupled.5. The syringe shield of claim 3 , wherein the radioactive emissions blocking material is selected from the group consisting of tungsten claim 3 , tungsten alloys claim 3 , molybdenum claim 3 , molybdenum alloys claim 3 , lead claim 3 , lead alloys claim 3 , lead-lined wood claim 3 , leaded glass claim 3 , polymer composite materials claim 3 , ceramic materials claim 3 , borated polymers claim 3 , and combinations thereof.6. The syringe shield of claim 1 , wherein the syringe bore is sized to accommodate a syringe having a diameter sufficient to hold 0.5 ml claim 1 , 1 ml claim 1 , 3 ml claim 1 , 5 ml 10 ml claim 1 , 15 ml claim 1 , 20 ml claim 1 , 30 ml claim 1 , 40 ml claim 1 , 50 ml claim 1 , 60 ml claim 1 , and combinations thereof.7. The syringe shield of claim 1 , further comprising an integrated cap.8. ...

Tubing connectors

Sealing connectors for use in connecting tubing to tubing, tubing to needles or other implements, syringe to tubing, or syringe to needles or other implements that provide reduced turbulence and sharp transitions are described herein.

MOLECULAR IMAGING VIAL TRANSPORT CONTAINER AND FLUID INJECTION SYSTEM INTERFACE

A pharmaceutical transport container includes a first body portion adapted to receive at least a portion of a pharmaceutical vial, a second body portion removably engaged with the first body portion to fully enclose the vial, and, optionally, a ratcheting mechanism to permit rotation of the cap member relative to the second body portion upon application of rotational force of a predetermined amount. A pharmaceutical transport container may also include, for example, a guide tab extending from an exterior surface of the second body portion to engage a guide slot defined in a fluid injection system docking station, whereby the transport container translates axially and rotationally into the docking station to establish a fluid connection between the vial and a fluid connector mechanism or element disposed within the docking station. 1. A pharmaceutical transport container , comprising:a first body portion adapted to receive at least a portion of a pharmaceutical vial and defining an opening for establishing fluid communication with the vial, and comprising a proximal end;a second body portion engaged with the first body portion to fully enclose the vial, the second body portion having a distal end engaged with the proximal end of the first body portion and a closed proximal end and defining an interior cavity therebetween; andwherein the second body portion is adapted to cooperate with a receiving docking station of a fluid injection system to establish a fluid connection between the vial and a fluid connector element disposed within the docking station as the second body portion is inserted axially into the docking station.2. The pharmaceutical transport container of claim 1 , further comprising at least one guide tab extending radially from an exterior surface of the second body portion or within the docking station claim 1 , the at least one guide tab configured to engage at lease one guide slot defined in the exterior surface of the second body portion or defined ...

INTERVENTIONAL CATHETER ASSEMBLIES, CONTROL SYSTEMS AND OPERATING METHODS

An interventional catheter assembly has an operating head and catheter system that are inserted and navigated within a patient's body while an operator controls the system externally of the operating head. An operating head is positioned at or near a distal end of the catheter system and coupled to a drive shaft and drive system for rotation. A guidewire brake control system interrupt prevents the drive system from being actuated when the guidewire brake is in a released position, and a selectable guidewire brake interrupt override control permits an operator to translate and/or rotate the drive shaft and operating head while the guidewire is simultaneously moved. This allows withdrawal of the guide wire and the operating head from the target site while rotating the operating head. 1. An interventional catheter assembly comprising: a catheter system forming at least one passageway and being sized and configured for introduction to and navigation through a body lumen or cavity to a target site; an operating head positioned at or near a distal end of the catheter system and coupled to a drive shaft and a drive system for rotation; a guidewire brake operable to clamp a guidewire in a stationary position when engaged and to allow translation and/or rotation of the guidewire through the brake when released; a guidewire brake control system interrupt that prevents the drive system from being actuated when the guidewire brake is in a release position , and a selectable guidewire brake interrupt override control that , when actuated , permits an operator to translate and/or rotate the drive shaft and operating head while the guidewire is simultaneously moved.2. The interventional catheter assembly of claim 1 , additionally comprising an aspiration lumen that communicates with a vacuum source during operation and provides aspiration of materials from the target site.3. The interventional catheter assembly of claim 1 , additionally comprising one or more material removal ...

CONSOLIDATED ATHERECTOMY AND THROMBECTOMY CATHETER

An atherectomy and thrombectomy system includes a catheter body extending between proximal and distal catheter portions. The catheter body includes an aspiration lumen extending therein. An atherectomy assembly is coupled with the distal catheter portion and includes a rotatable cutter. A thrombectomy assembly is coupled with the distal catheter portion. The thrombectomy assembly includes a jet body within the aspiration lumen, and inflow and outflow orifices extending through the catheter body and in communication with the aspiration lumen. In a thrombectomy configuration a cyclical flow is generated by the jet body through the outflow and inflow orifices to hydrodynamically abrade thrombus, the cyclical flow entrains thrombus and delivers thrombus into the aspiration lumen. In the atherectomy configuration the rotatable cutter cuts plaque into plaque particulate, and the cyclical flow of the thrombectomy assembly entrains the particulate and delivers the particulate into the aspiration lumen. 1. An atherectomy and thrombectomy system comprising:a catheter body extending from a proximal catheter portion to a distal catheter portion, the catheter body including an aspiration lumen extending from the distal catheter portion to the proximal catheter portion;an atherectomy assembly coupled with the distal catheter portion, the atherectomy assembly includes a rotatable cutter; a jet body within the aspiration lumen,', 'an inflow orifice extending through the catheter body and in communication with the aspiration lumen, and', 'an outflow orifice extending through the catheter body and in communication with the aspiration lumen, the inflow orifice is closer to the jet body than the outflow orifice;, 'a thrombectomy assembly coupled with the distal catheter portion, the thrombectomy assembly, the thrombectomy assembly is operable in atherectomy and thrombectomy configurations, the thrombectomy assembly includesin the thrombectomy configuration a cyclical flow is generated ...

MULTI-FLUID MEDICAL INJECTOR SYSTEM AND METHODS OF OPERATION

A multi-fluid injector system and methods of operation thereof are presented. One embodiment of such a fluid injector system includes an automatic refill procedure for a fluid injector system comprising a fluid injector and an operably engaged syringe. The procedure includes the step of determining, using an electronic control device operably controlling the fluid injector system, whether a fluid injection procedure involving the syringe is impending. If the electronic control device determines that the fluid injection procedure is not impending, such that the automatic refill will not interfere with the fluid injection procedure, an automatic refill of the syringe is initiated. 1. An automatic refill procedure for a fluid injector system comprising a fluid injector and an operably engaged syringe , comprising:determining, using an electronic control device operably controlling the fluid injector system, whether a fluid injection procedure involving the syringe is impending; andinitiating an automatic refill of the syringe if the electronic control device determines that the fluid injection procedure is not impending, such that the automatic refill of the syringe will not interfere with the impending fluid injection procedure.2. An automatic refill procedure as claimed in claim 1 , wherein the electronic control device determines whether the fluid injection procedure involving the syringe is impending based at least partially on inactivity of at least one component of the fluid injector system for a certain period of time.3. An automatic refill procedure as claimed in claim 2 , wherein the at least one component of the fluid injector system comprises a hand controller claim 2 , and wherein inactivity of the hand controller for a certain period of time indicates that the fluid injection procedure involving the syringe is not impending claim 2 , such that the automatic refill of the syringe will not interfere with the impending fluid injection procedure.4. An ...

Apparatus and Methods for Delivery of Fluid Injection Boluses to Patients and Handling Harmful Fluids

A hazardous fluid transport container and a hazardous fluid delivery system are disclosed. The hazardous fluid transport container includes a housing enclosing an at least partially shielded enclosure. First and second fluid path elements are disposed within the housing, with the first fluid path element and second fluid path element fluidly coupled together. A pump unit may be provided for dispensing fluid from the first and second fluid path elements optionally into a third fluid path element. Also, methods for priming the hazardous fluid transport container and for mitigating laminar flow injection bolus spreading are disclosed. Additionally, disclosed is a radioactive fluid transport container for a syringe or other container. The radioactive fluid transport container allows the syringe or container to be used in an injection procedure without removal from the container.

OVERMOLDED MEDICAL CONNECTOR TUBING AND METHOD

A high pressure medical connector tubing assembly includes a high pressure medical connector tubing assembly, including a tube element having opposed tube ends and a passageway, an end element overmolded to at least one of the opposed tube ends, the end element having an annular end portion having a preselected length, and a connector element having a connector hub defining a receiving cavity. The preselected length of the annular end portion may be used to pre-control the axial location of stress concentration in the connector hub. A method of forming the high pressure medical connector tubing assembly includes providing a tube element comprising opposed tube ends and a passageway therethrough, overmolding an end element onto at least one of the opposed tube ends, providing a connector element comprising a connector hub defining a receiving cavity, and securing the tube end with the overmolded end element in the receiving cavity. 2. A high pressure medical connector tubing assembly as claimed in claim 1 , wherein the tube end with the overmolded end element is fixedly secured in the receiving cavity by solvent bonding.3. A high pressure medical connector tubing assembly as claimed in claim 1 , wherein the end element is formed with at least one external indicator to visibly identify depth of insertion of the tube end with the overmolded end element in the receiving cavity.4. A high pressure medical connector tubing assembly as claimed in claim 1 , wherein the tube element comprises braided tubing formed of an inner braid encapsulated by a flexible polymer layer.5. A high pressure medical connector tubing assembly as claimed in claim 1 , wherein the connector element comprises a connector port defining a fluid passageway.6. A high pressure medical connector tubing assembly as claimed in claim 5 , wherein the annular end portion defines a tapered entranceway tapering from the fluid passageway to the passageway in the tube element.7. A high pressure medical connector ...

QUICK RELEASE PLUNGER

A syringe system and components thereof are disclosed. The system may include a syringe body having a hollow lumen, a proximal open end, and a distal end. The syringe body may be configured to house a fluid therein. The syringe system may further include a plunger positioned in the hollow lumen of the syringe body, forming a seal with an inner wall of the syringe body. The plunger may include a removable piston having a shaft extending from the distal end towards the proximal open end, a stopper removably connected to a distal portion of the shaft, and at least one coupler attached to the distal portion of the shaft. The stopper may be configured to slidably move within the hollow lumen to facilitate movement of the fluid within the syringe body. The coupler may be configured to facilitate removal and attachment of the stopper from the piston. 1. A syringe system comprising:a syringe body comprising a hollow lumen, a proximal open end, and a distal end, the syringe body being configured to house a fluid therein; and a removable piston having a shaft extending from the distal end towards the proximal open end,', 'a stopper removably connected to a distal portion of the shaft, the stopper configured to slidably move within the hollow lumen to facilitate movement of the fluid within the syringe body, and', 'at least one coupler at the distal portion of the shaft, wherein the coupler is configured to facilitate removal and attachment of the stopper from the piston., 'a plunger positioned in the hollow lumen of the syringe body, forming a seal with an inner wall of the syringe body, the plunger comprising2. The syringe system of claim 1 , wherein the stopper comprises a cylindrical body and a conical protrusion tip claim 1 , the protrusion tip sized and configured to substantially fill at least a portion of the distal end of the syringe body.3. (canceled)4. The syringe system of claim 1 , wherein the coupler includes one or more fastening mechanisms configured to attach ...

Infusion flow guidewire system

An infusion flow guidewire and a system including an infusion flow guidewire. The minimal cross section flexible infusion flow guidewire includes a nitinol hypotube, a flexible tip having a closed distal end, a coil, a core wire and at least one distally located rearwardly directed jet orifice for infusion of fibrinolytics and for introduction of high pressure fluids for maceration and rearwardly directed flow of thrombus debris located in tortuous small sized vessels. Apparatus, some of which is removably attachable, is provided in the system for grasping members of the invention for rotational torqueing and for longitudinal actuation along and within the vasculature.

Graphene photonic device

Provided is a graphene optical device. The optical device includes a lower clad, an optical waveguide extended on the lower clad in a first direction, a first dielectric layer disposed on the optical waveguide, and a graphene layer extended on the first dielectric layer in a second direction.

Fluid Delivery System with High and Low Pressure Hand Manifold

A fluid delivery system is provided and includes a power injector supporting a high pressure syringe. The fluid delivery system further includes a manifold and a low pressure hand-operated syringe. The manifold generally includes a plurality of fluid control valves in series fluid communication. A first fluid control valve of the plurality of fluid control valves has a first port, a second inlet port, and a third port. The third port of the first fluid control valve is in fluid connection with a first port of a second fluid control valve. The low pressure hand-operated syringe is in fluid connection with the first port of the first fluid control valve, and the high pressure syringe is in fluid connection with the second port of the first fluid control valve. The fluid control valves may be multi-position stopcock valves. 1. A fluid path set for a fluid delivery system , comprising:a manifold comprising a plurality of fluid control valves in series fluid communication, a first fluid control valve comprising a first port, a second port, and a third port, the third port of the first fluid control valve in fluid connection with a first port of a second fluid control valve;a low pressure hand-operated syringe in fluid connection with the first port of the first fluid control valve; anda high pressure syringe in fluid connection with the second port of the first fluid control valve.2. A fluid path set as claimed in claim 1 , wherein the fluid control valves comprise multi-position stopcock valves.3. A fluid path set as claimed in claim 1 , wherein the manifold further comprises a manifold housing claim 1 , and the fluid control valves are in friction-fit connection within the manifold housing.4. A fluid path set as claimed in claim 1 , wherein the manifold comprises an L-shaped manifold housing comprising a longitudinal portion and a lateral portion claim 1 , and wherein the second port of the first fluid control valve is generally coaxial with the lateral portion.5. A ...

Delivery and administration of compositions using interventional catheters

Systems and methods for delivery of therapeutic and/or diagnostic compositions to an interventional site having diseased or newly treated tissue are provided. Integrated interventional catheter systems incorporating surfaces coated with a diagnostic or therapeutic composition, or ports for infusing a diagnostic or therapeutic composition prior to, during or following an interventional procedure are provided.

SYSTEM AND METHOD FOR RAPID QUANTITATIVE DYNAMIC MOLECULAR IMAGING SCANS

Methods and systems for controlled administration of a tracer and quantification of uptake of the tracer by a target organ are described herein. 1. A method for imaging tissue comprising:administering a tracer;determining an input function for the tracer in a high blood volume organ;determining an injection profile for administering the tracer based on at least one pharmacokinetic (PK)/pharmacodynamic (PD) parameter determined from the input functionimaging a target tissue; andrepeating the steps for determining an input function for the tracer in the high blood volume organ and imaging the target tissue.2. The method of claim 1 , wherein administering the tracer comprises bolus injection of the tracer.3. The method of claim 1 , wherein administering the tracer comprises slow injection of the tracer over a period of time.4. The method of claim 3 , wherein the period of time comprises a time period selected from the group consisting of about 30 seconds claim 3 , about 60 seconds claim 3 , about 120 seconds claim 3 , about 240 seconds claim 3 , and about 360 seconds.5. The method of claim 1 , wherein administering comprises delivering the tracer at a rate that is slower than an average circulation time of the tracer in the blood.6. The method of claim 1 , wherein administering comprises a bolus injection of a first amount of the tracer followed by an infusion of a second amount of the tracer.7. (canceled)8. The method of claim 1 , wherein determining the input function comprises determining a plasma concentration of the tracer.9. The method of claim 8 , wherein determining the plasma concentration comprises determining a concentration of tracer for whole blood claim 8 , determining a concentration of tracer for red blood cells claim 8 , and subtracting the concentration of tracer for red blood cells from the concentration of tracer from whole blood.10. The method of claim 1 , further comprising identifying a maximum blood volume after administering the tracer and ...

CONFIGURABLE PROCESS CONTROL DEVICE WITH ELECTRONIC DISPLAY ASSEMBLY

A configurable process control device, which includes a field device, such as a valve position controller, that can be configured by a user to emulate any one of a plurality of different types of process control devices, is provided with an electronic display assembly. The electronic display assembly is operatively connected with a control circuit that is arranged to respond to the specific configuration of the field device to cause the electronic display assembly to display information relevant to the specific type of control device the field device has been configured to emulate. The information may include safety certification information specific to each of the different types of process control devices that the field device can be configured to emulate. 1. A configurable process control device for use in a plurality of use environments , wherein at least one of a pre-defined plurality of certifications must be displayed in conjunction with the configurable process control device depending on which of the use environments the configurable process control device is to be used in , the configurable process control device comprising:a field device;a first control circuit operatively coupled to the field device, the first control circuit arranged to control the field device and arranged to be reconfigured by a user to allow the field device to selectively emulate any of a plurality of different process control device types;an electronic display assembly, the electronic display assembly arranged to selectively display different information; anda second control circuit, the second control circuit operatively coupled to the electronic display assembly and the first control circuit, the second control circuit having access to a plurality of different certification information sets, each certification information set corresponding to a different one of the plurality of different process control device types;wherein the second control circuit causes the electronic display ...

Hand Controller Support Assembly for a Fluid Delivery System

A fluid delivery system is provided, including a fluid injector head, a hand controller electronically interfaced with the fluid injector head, and a hand controller support assembly for supporting the hand controller. The hand controller support assembly includes a first component having a base portion and two outward extending support arms to support the hand controller and a second component adapted for fixation to a surface. The first component may be rotationally connected to the second component such that the first component may automatically reposition relative to the second component under the force of gravity to maintain the hand controller in an upright position and supported by the support assembly. 1. A hand controller support assembly , comprising:a first component comprising a base portion and two outward extending support arms to support the hand controller;a second component adapted for fixation to a surface; andwherein the first component is rotationally connected to the second component such that the first component may automatically reposition relative to the second component under the force of gravity to maintain the hand controller in an upright position and supported by the support assembly.2. A hand controller support assembly as claimed in claim 1 , wherein the second component comprises an L-shaped body comprising a first leg and a second leg defining approximately a 90° angle between one another.3. A hand controller support assembly as claimed in claim 2 , wherein the first leg is longer than the second leg.4. A hand controller support assembly as claimed in claim 2 , wherein the first leg defines a longitudinal slot between two arm portions claim 2 , the longitudinal slot formed with a circular recess to receive a support post extending from the base portion of the first component to enable rotational movement of the first component relative to the second component.5. A hand controller support assembly as claimed in claim 2 , wherein the ...

System for Processing Cells and Container for Use Therewith

A system for processing cells (and/or other injectate components) includes a container and a plunger adapted to be slidably positioned within the container. The system includes at least one inlet port through which a fluid can enter the system and at least one effluent port through which an effluent can exit the system. The plunger section forms a sealing engagement with the inner wall of the container such that rearward motion of the plunger is adapted to draw fluid into the system via the inlet and forward motion of the plunger is adapted to force effluent out of the system via the effluent port. 1. A container adapted to store and transport an injectate , the container comprising:a first port at a first axial position within the container;a first piercing member having a distal end and extending through a septum of the container;at least a second port at a second axial position within the container, the first axial position and the second axial position being different; anda second piercing member having a distal end extending through an end closure of the container, the first port being disposed on the distal end of the first piercing member and the second port being disposed on the distal end of the second piercing member;wherein the container encompasses viable cells within a first fluid and at least one of the first axial position and the second axial position is above an axial position of cells settled on or adjacent to a bottom of the container.2. The container of wherein the cells are retinal pigment epithelial cells supported on microspheres claim 1 , mesenchymal stem cells claim 1 , multipotent adult progenitor cells claim 1 , embryonic stem cells claim 1 , cardiac precursor cells claim 1 , cardiac cells claim 1 , beta-islet precursor cells claim 1 , beta-islet cells claim 1 , neural precursor cells claim 1 , or neural cells.3. The container of comprising a divider disposed within the container and adapted to create a first fluid path on a first side of ...

Multi-Channel Endorectal Coils and Interface Devices Therefor

An intracavity probe for use with a magnetic resonance system includes: a pair of coil loops arranged in a phased array configuration; a pair of decoupling circuits; a pair of output cables; and a spacer material positioned adjacent to an anterior surface of the coil loops. Each coil loop has a drive capacitor and a tuning capacitor. Each decoupling circuit is connected across the tuning capacitor of one of the coil loops. Each output cable is connected at a first end thereof across the drive capacitor of one of the coil loops such that each of the drive capacitors is provided with a separate ground. The spacer material assures a predetermined distance between the pair of coil loops and the region of interest, which thereby reduces intensity of the magnetic resonance signals in proximity to the coil loops, maintains SNR at depth within the region of interest and reduces artifacts. 1. A coil for use with a magnetic resonance system for obtaining images of a region of interest , the coil comprising:(a) a pair of coil loops arranged in a phased array configuration each of which receives magnetic resonance signals from the region of interest corresponding thereto, each of the coil loops having a drive capacitor and a tuning capacitor with the tuning capacitor having a value selected to resonate the coil loop corresponding thereto at an operating frequency of the magnetic resonance system; and(b) a spacer material positioned adjacent to an anterior surface of the pair of the coil loops, the spacer material enabling a predetermined distance of between about 0.03 and about 0.06 inches to exist between the pair of coil loops and the region of interest and thereby:(i) reduces intensity of the magnetic resonance signals in proximity of the coil loops;(ii) maintains a signal-to-noise ratio at a depth within the region of interest appropriate to reconstruct the images of the region of interest; and(iii) reduces artifacts in the images inclusive of the Gibbs artifact.2. The coil ...

PIEZOELECTRIC LOUDSPEAKER

The present invention discloses a piezoelectric loudspeaker. The piezoelectric loudspeaker comprises a sound producing plate, a resonant sound-box, a surround and a reflective sound-box. The sound producing plate comprises a piezoelectric ceramic element. The resonant sound-box includes a first opening comprising a first carrying part. The sound producing plate is disposed on the first carrying part. A cavity resonator is formed between the sound producing plate and the resonant sound-box. The surround is disposed between the first carrying part and the sound producing plate. The reflective sound-box includes a second opening and a reflective output opening. The second opening comprises a second carrying part. The resonant sound-box is disposed on the second carrying part. A reflective cavity body is formed between the resonant sound-box and the reflective sound-box, and the reflective cavity body is connected the reflective output opening. 1. A piezoelectric loudspeaker , comprising:a sound producing plate including at least one piezoelectric ceramic element being able to vibrate the sound producing plate;a resonant sound-box including a first opening comprising a first carrying part, the sound producing plate being disposed on the first carrying part, and a cavity resonator being formed between the sound producing plate and the resonant sound-box;a surround disposed between the first carrying part and the sound producing plate; anda reflective sound-box including a second opening and a reflective output opening, a second carrying part formed on a partial of an inner edge of the seconding opening, the resonant sound-box being disposed on the second carrying part, a reflective cavity body being formed between the resonant sound-box and the reflective sound-box, the reflective output opening being disposed on a side of the reflective sound-box, and the reflective cavity body being communicating with the reflective output opening.2. The piezoelectric loudspeaker of ...

INTELLIGENT CONTRAST WARMER AND CONTRAST HOLDER

Intelligent contrast warmers and methods for operating and using same are described. An intelligent contrast warmer may include elements configured to monitor information associated with the intelligent contrast warmer and contrast media stored in contrast bottles housed within the intelligent contrast warmer, such as contrast warmer temperatures, contrast warmer temperatures outside of specifications, contrast media inventory, expiration dates of contrast media, personnel authorized to access contrast media, and dates and times associated with contrast media added to and removed from the intelligent contrast warmer. A method for monitoring the expiration date of contrast bottles may include labeling the contrast bottles and reading the information from the label into a computing device. The computing device may be configured to monitor the expiration dates and to generate an alarm responsive to a current time being within a threshold duration of the expiration time for a contrast bottle. 1. A contrast warmer configured to warm contrast bottles stored therein , the contrast warmer comprising:a temperature sensor operative to measure a temperature of the contrast warmer; anda communications port in operative communication with at least one computing device configured to monitor the temperature,wherein an alarm event is generated by the at least one computing device responsive to the temperature being outside of an acceptable temperature range.2. The contrast warmer of claim 1 , wherein a record of the alarm event is stored in a database on the at least one computing device.3. The contrast warmer of claim 2 , wherein contrast information is stored in the database stored on the at least one computing device claim 2 , the contrast information comprising information associated with the alarm event occurring during storage of the contrast bottles in the contrast warmer.4. A method of monitoring an expiration time of a contrast bottle stored in a contrast warmer claim 2 , ...

METHODS AND SYSTEMS FOR MONITORING AN AUTOMATED INFUSION SYSTEM

Methods and systems for monitoring an automated radiopharmaceutical infusion apparatus are disclosed. A user interface graphically representing infusion apparatus components may be presented on a display device. Multiple sensors may be arranged within an infusion apparatus to measure property information associated with infusion apparatus components, including fluid pathways. The property information may include radioactivity and flow information. The property information may be compared with expected results. If the property information does not match the expected results, a fault condition may be indicated on the display device. The user interface may provide information and/or functions to manage the fault conditions. 1. A system for monitoring an automated radiopharmaceutical infusion apparatus , the system comprising:a plurality of fluid pathways comprising a radiopharmaceutical source pathway;a plurality of sensors positioned to measure at least one property associated with the plurality of fluid pathways, the at least one property comprising radioactivity;a display device;a processor in communication with the plurality of sensors and the display device; and 'receive property information from the plurality of sensors,', 'a non-transitory, computer-readable storage medium in operable communication with the processor, wherein the computer-readable storage medium contains one or more programming instructions that, when executed, cause the processor to compare the property information with expected results,', 'generate a fault condition responsive to property information not matching the expected results, and', 'graphically represent the fault condition on the apparatus display., 'present an apparatus display graphically representing apparatus components based on the property information on the display device,'}2. The system of claim 1 , wherein the plurality of fluid pathways further comprise at least one of a saline pathway claim 1 , a dose meter inlet pathway ...

BENT SYRINGES AND DEVICES INCLUDING SAME

Bent syringes, mounting systems for bent syringes, and devices incorporating bent syringes are described herein. The syringes include a bent cylindrical body bent about a radius and a plunger bent about the radius of the bent cylindrical body and configured and arranged to be received by the proximal open end of the bent cylindrical body and movably disposed within at least a portion of the bent cylindrical body. 1. A syringe , comprising:a bent cylindrical body bent about a radius, the bent cylindrical body having a proximal open end and a distal conical end, the conical end comprising at least one discharge outlet; anda plunger having a curvature substantially similar to the curvature of the bent cylindrical body configured and arranged to be received by the proximal open end of the bent cylindrical body and movably disposed within at least a portion of the bent cylindrical body.2. The syringe of claim 1 , wherein the radius is from about 30° to about 180°.3. The syringe of claim 1 , wherein the radius is from about 45° to about 100°.4. The syringe of claim 1 , wherein the radius is about 90°.5. The syringe of claim 1 , further comprising a hinge disposed at an intersection of a radius of the bent cylindrical body and a radius of the plunger and operably connecting to the bent cylindrical body and the plunger.6. The syringe of claim 5 , wherein the plunger further comprises a plunger arm connecting the hinge and a proximal end of the plunger.7. The syringe of claim 5 , further comprising at least one drive motor operably connected to one of the bent cylindrical body or the plunger.8. The syringe of claim 5 , further comprising at least one drive motor operably connected to each of the bent cylindrical body and plunger.9. The syringe of claim 5 , further comprising a spindle received by the hinge and operably connected to one of the bent cylindrical body or the plunger.10. The syringe of claim 9 , further comprising a drive motor operably connected to the spindle. ...

THROMBECTOMY CATHETER

A thrombectomy catheter includes a catheter body extending from a catheter proximal portion to a catheter distal portion and including a catheter intermediate portion, the catheter body includes an aspiration lumen and an infusion lumen extending along the catheter body, wherein the aspiration lumen includes an aspiration orifice open at a distal end of the catheter body. 1. A thrombectomy catheter comprising:a catheter body extending from a catheter proximal portion to a catheter distal portion and including a catheter intermediate portion, the catheter body including an aspiration lumen and an infusion lumen extending along the catheter body, the catheter body having an integral homogenous cross-section profile and having a multi-durometer hardness varying along the catheter body's length such that the catheter proximal portion has a relatively high durometer value and the catheter distal portion has a relatively low durometer value, with respect to each other;wherein the aspiration lumen includes an aspiration orifice open at a distal end of the catheter body; andwherein the infusion lumen extends along the catheter body towards the distal portion and includes a single infusion orifice that is configured to direct a fluid jet radially away from a longitudinal axis of the catheter body.2. The thrombectomy catheter of claim 1 , wherein the distal end of the catheter body includes an aspiration orifice distal member including a proximal portion extending from the distal end of the catheter body having an opening sized similar to the aspiration lumen and a distal portion having an opening wider than the aspiration lumen.3. The thrombectomy catheter of claim 1 , wherein the aspiration lumen is free from structural obstructions along a length of the catheter body.4. The thrombectomy catheter of claim 1 , wherein the aspirating orifice includes a circular cross-section shape.5. The thrombectomy catheter of claim 1 , wherein the single infusion orifice is recessed ...

BOTTLE SPIKE WITH WIDE-BORE INTRODUCER

Systems and methods for enabling high fluid rate injections are disclosed. The system includes a hollow dip tube, an introducer and a sharp tip-end. The introducer has a hollow sleeve that includes an opening at a proximal end. The sharp-tip end is located at a distal end of the introducer and is configured to pierce a septum of a container. The introducer is configured to receive the dip tube through the opening. Fluid may be withdrawn from the container through the dip tube upon insertion. In some cases, the dip tube separates the tip-end from the introducer when it is inserted through the opening. In other cases, the tip-end remains seated in the introducer and allows fluid to pass through it as it is withdrawn from the container. 1. A system for enabling high fluid rate injection , the system comprising:a hollow dip tube;an introducer having a hollow sleeve, wherein the hollow sleeve comprises an opening at a proximal end, wherein the introducer is configured to receive the hollow dip tube through the opening; anda sharp tip-end located at a distal end of the introducer, wherein the sharp tip-end is configured to pierce a septum of a container.2. The system of claim 1 , wherein the introducer comprises a surface configured to seal against a lip of a container surrounding a septum pierced by the sharp tip-end.3. The system of claim 1 , wherein the introducer comprises an air filter surrounding the opening of the hollow sleeve.4. The system of claim 1 , wherein a distal end of the hollow dip tube is configured to receive the sharp tip-end when the introducer receives the hollow dip tube through the opening.5. The system of claim 1 , wherein the sharp tip-end is separable from the introducer.6. The system of claim 5 , wherein the sharp tip-end is further configured to separate from the introducer upon receiving a distal end of the hollow dip tube through the opening.7. The system of claim 5 , wherein the sharp tip-end comprises a buoyant material.8. The system of ...

INTERVENTIONAL CATHETER HOUSING ASSEMBLIES INCORPORATING GUIDE WIRE BRAKES AND MANAGEMENT SYSTEMS

Interventional catheter assemblies that operate over a guide wire are disclosed. Specifically, an elongated flexible catheter is associated at its proximal end with a housing having a guide wire port where the guide wire exits the housing. The housing additionally incorporates a guide wire brake mounted within a slot positioned a distance from the guide wire port for engaging and releasing a guide wire. The slot is generally arranged at an angle to the path of the guide wire as it exits the guide wire port. When the guide wire is clamped in the angled slot, variable lengths of exposed guide wire accumulate in a substantially unrestrained condition when the flexible catheter is advanced and retracted relative to the guide wire, allowing movement of the distal end of the catheter over considerable distances without repositioning and re-clamping the proximal end of the guide wire. 1. An interventional catheter housing assembly comprising: a housing having a top wall , a bottom wall , and a plurality of side walls enclosing at least one interventional catheter operating component; a catheter feedthrough penetrating the housing; a guide wire exit port for slidably receiving a guide wire; an angled slot provided in the top wall , the bottom wall , or a side wall of the housing and positioned a distance from the guide wire exit port; and a guide wire clamp provided within the housing and positioned for operating within the angled slot that , in a closed , actuated condition prevents both rotation and axial translation of the guide wire positioned in the angled slot.2. The interventional catheter housing assembly of claim 1 , wherein the catheter feedthrough is positioned at a first housing location and the guide wire exit port is positioned at a housing location spaced from and generally opposite the first housing location.34-. (canceled)5. The interventional catheter housing assembly of claim 1 , wherein the angled slot is arranged at an angle of greater than 15° and less ...

METHODS AND SYSTEMS FOR DOSING CONTROL IN AN AUTOMATED FLUID DELIVERY SYSTEM

Methods and systems for dispensing a fluid using an automated fluid delivery system are disclosed. A pump may be configured to force an aliquot of fluid into a fluid delivery channel. A processor may receive values of a property for the aliquot and the source of the aliquot. The processor may use the values to determine the volume of the aliquot. The determined volume is compared by the processor against an expected volume to establish the amount of fluid being pumped by the pump per unit, such as time or revolutions. The processor controls operation of the pump to dispense a predetermined dose based on the amount of fluid being pumped by the pump per unit. 1. A system for dispensing a fluid , comprising:a pump configured to force an aliquot of fluid from a fluid source into a fluid delivery channel;at least one sensor configured to measure a sample value of a property of the aliquot;a processor in communication with the pump and the sensor; and receive the sample value,', 'receive a source value of the property for the fluid source,', 'determine a volume of the aliquot based on a comparison of the sample value and the source value, and', 'control operation of the pump to dispense a predetermined dose of the fluid based on a comparison of the sample volume with an expected volume., 'a non-transitory, computer-readable storage medium in operable communication with the processor, wherein the computer-readable storage medium contains one or more programming instructions that, when executed, cause the processor to2. The system of claim 1 , wherein the computer-readable storage medium further contains one or more programming instructions that claim 1 , when executed claim 1 , cause the processor to determine a pump coefficient based on the comparison of the sample volume with the expected volume claim 1 , the pump coefficient being configured to indicate a volume of fluid forced into the fluid delivery channel per unit.3. The system of claim 2 , wherein the pump ...

VALVELESS PET INFUSION SYSTEM

A device for delivery of a radiopharmaceutical and, in some embodiments, delivery of a pharmaceutical agent are provided herein. 1. A device for delivering a pharmaceutical comprising:two or more roller pumps; a first tubing section fluidly connecting to a pharmaceutical source to a confluence, wherein flow of fluid through the first tubing section is controlled by a first roller pump;', 'a second tubing section fluidly connecting a source of medical fluid to the confluence, wherein flow of fluid through the second tubing section is controlled by a second roller pump; and', 'a third tubing section fluidly connecting the confluence to an exit port., 'a fluid path set reversibly attached to the device, the fluid path set comprising2. The device of claim 1 , further comprising a tubing section for delivering fluid to a patient reversibly connected to the exit port.3. The device of claim 1 , further comprising a fourth tubing section fluidly connecting the third tubing section or a portion thereof to a waste receptacle.4. The device of claim 3 , wherein the device further comprises a third roller pump configured to control fluid flow through the fourth tubing section.5. The device of claim 3 , wherein a T-joint connects the third tubing section to the fourth tubing section.6. The device of claim 1 , further comprising a waste by-pass tubing section connecting an upstream portion of the fourth tubing section with a downstream portion of the fourth tubing section.7. The device of claim 6 , wherein flow of fluid through the waste by-pass tubing section is controlled by the second roller pump.8. The device of claim 6 , wherein the waste by-pass tubing section is fluidly connected to the upstream portion of the fourth tubing section by a T-joint claim 6 , and the waste by-pass tubing section is connected to the downstream portion of the fourth tubing section by a T-joint.9. The device of claim 6 , wherein fluid from the fluid source can flow through the second tubing section ...

INFORMATION SENSING SYRINGE

Syringe systems and flow control systems configured to detect information associated with a liquid material are described. The syringe systems may include a syringe body for housing the liquid material and an injector piston for expelling the liquid material out of the syringe through a discharge outlet at a distal end of the syringe body. Components of the syringe, such as an injector piston, may include sensors configured to measure and/or detect a property of the liquid material, such as concentration, pH, or radioactivity. The flow control system may include a pinch valve and a platen arranged about a fluid delivery channel. Flow within the fluid delivery channel may be controlled by increasing (squeezing the fluid delivery channel) or decreasing the distance between the pinch valve and the platen. Components of the flow control system may include detectors configured to detect properties of fluid in the fluid control channel. 1. A syringe system comprising:a syringe body comprising a proximal open end and at least one distal discharge outlet, the syringe body being configured to house a liquid substance;a plunger positioned in the syringe body forming a seal with an inner wall of the syringe body;an injector piston configured to be received by the proximal open end and to slide within the syringe body, the injector piston being configured to engage the plunger as it slides within the syringe body to expel the liquid substance through the at least one discharge outlet; andat least one sensor configured to measure at least one property of the liquid substance.2. The system of claim 1 , wherein the at least one sensor is positioned within the injector piston.3. The system of claim 1 , wherein the at least one sensor is not in contact with the liquid.4. The system of claim 1 , wherein the at least one sensor is selected from the group consisting of radiation sensors claim 1 , pH sensors claim 1 , optical sensors claim 1 , analyte sensors claim 1 , concentration ...

System and Method for Injection Protocol Management

A fluid injection system for controlling at least one fluid delivery system is provided. The fluid injection system includes at least one computing device in communication with the at least one fluid delivery system. The at least one computing device is configured to: display, on or with at least one display device, at least one graphical user interface configured to facilitate a user selection of at least one injection protocol of a plurality of injection protocols; receive, from at least one user, at least one selected injection protocol from the plurality of injection protocols; retrieve, from at least one remote server computer, the at least one selected injection protocol; and control the at least one fluid delivery system based at least partially on the at least one selected injection protocol. 1. A fluid injection system for controlling at least one fluid delivery system , the fluid injection system comprising at least one computing device in communication with the at least one fluid delivery system , the at least one computing device configured to:display, on or with at least one display device, at least one graphical user interface configured to facilitate a user selection of at least one injection protocol of a plurality of injection protocols;receive, from at least one user, at least one selected injection protocol from the plurality of injection protocols;retrieve, from at least one remote server computer, the at least one selected injection protocol; andcontrol the at least one fluid delivery system based at least partially on the at least one selected injection protocol.2. The fluid injection system of claim 1 , wherein the at least one computing device is further configured to transmit claim 1 , to the at least one remote server computer claim 1 , a request to search at least one injection protocol database based at least partially on at least one search parameter claim 1 , the at least one search parameter comprising at least one of the following: a ...

Item Eligibility and/or Promotion Determination Application

In general, the present invention is directed to systems and methods of utilizing an application operating on a mobile device to determine any applicable offers or eligibility and rank such offers and eligibility for user selection. More specifically, a process may be conducted by a processor in communication with a mobile device and data stores including user data, retailer data, and/or product and service data, the process including comparing identification information associated with a product or service received from the mobile device with data in the data stores; determining the product or service and identifying any associated promotional offers or plan eligibility associated with the product or service, the user, and/or the retailer; ranking any promotional offers or plan eligibility based at least in part on size of promotion; transmitting to the mobile device an identifier of applicable promotional offers or plan eligibility. 1. A system , comprising:a processor; user data, including memberships, groups, plans, and/or entitlements associated with a user;', products and services offered by a retailer;', 'any promotional offers offered by the retailer;, 'retailer data, including, 'product and service data, including identification information of each product and service, and any promotional offers or plan eligibility associated with the product or service;, 'one or more data stores, the one or more data stores storing data comprisingwherein the processor is in selective communication with one or more retailers, manufacturers, membership plans, insurance providers, and/or entitlement providers to populate and update the one or more data stores;wherein the processor is in selective communication with a mobile device of the user; comparing first media data comprising identification information associated with a product or service received from the mobile device with product and service data stored in the one or more data stores;', 'based at least in part on the ...

TREADMILL AUTOMATED DOSING USER INTERFACE

Methods and systems for dispensing a radionuclide are disclosed. A processor may receive one or more physiological signals for a patient from one or more physiological parameter sensors. The processor may compare the physiological signals with one or more threshold values. The processor may cause an injector device to dispense the radionuclide in response to the one or more physiological signals meeting or exceeding the one or more threshold values. The threshold values may be determined at least in part based on one or more characteristics of the patient.

Modality work list system

Methods and systems for automatically and dynamically determining a dose of a radiopharmaceutical are disclosed. The dose may be determined based on, among other things, radiopharmaceutical information associated with at least one source of a radiopharmaceutical, patient information and schedule information. An estimated radioactivity level may be determined based on an initial radioactivity level, a delivery time, a radioactivity decay rate, and an anticipated arrival time. A volume of the radiopharmaceutical to inject into a patient to deliver a dose of radioactivity may be determined based on the estimated radioactivity level and patient dosing information. An infusion apparatus may operate to inject the patient with the volume of the radiopharmaceutical.

DOUBLE ACTION INFUSION PUMP

An infusion system includes a double action infusion pump. The pump includes a cylinder and a reciprocating piston received within the cylinder, the reciprocating piston separating a first pump chamber from a second pump chamber of the cylinder. A reciprocating motor is coupled with the reciprocating piston, and the first and second pump chambers alternate between filling and evacuating conditions with reciprocation of the reciprocating piston through operation of the reciprocating motor, and the speed of reciprocation is varied to provide a continuous output of fluid between the first and second pump chambers. A fluid source and a catheter are optionally coupled with the double action infusion pump. The catheter includes one or more infusion ports near a catheter distal portion, and the one or more infusion ports receive and expel the continuous output of fluid from the double action infusion pump.

ADJUSTABLE VOLUME SYRINGE

Adjustable volume syringes, and systems and methods for using the same, are disclosed. An adjustable volume syringe may include a delivery syringe, a reservoir syringe located at least in part within the delivery syringe, and a reservoir plunger located at least in part within the reservoir syringe. The delivery syringe is configured to contain a first amount of a fluid. The reservoir syringe is configured to contain a second amount of the fluid. An administration amount of fluid may be determined at or prior to an administration time. An amount of fluid in the delivery syringe may be adjusted to an administration amount at or prior to the administration time based on whether the administration amount is greater than, less than or equal to the first amount. The administration amount of fluid may be dispensed to a patient at the administration time.

Fluid Path Set with Turbulent Mixing Chamber, Backflow Compensator

A fluid path set includes a first fluid line having a proximal end fluidly connectable to a source of a first fluid and a second fluid line having a proximal end fluidly connectable to a source of a second fluid. A flow mixing device is in fluid communication with distal ends of the first and second fluid lines. The flow mixing device includes a housing, a first fluid port provided for receiving the first fluid, and a second fluid port for receiving the second fluid. A mixing chamber is disposed within the housing and is in fluid communication with the first and second fluid ports. A third fluid port in fluid communication with the mixing chamber for discharging a mixed solution of the first and second fluids. A turbulent flow inducing member is disposed within the mixing chamber for promoting turbulent mixing of the first and second fluids.

Connector Assembly for Syringe System

A connector assembly for a fluid delivery system includes a conical body defining an interior cavity and a discharge outlet, the discharge outlet defining an internal passage in fluid communication with the interior cavity; and a connector removably attached to the discharge outlet. The connector includes a central body configured to be at least partially positioned within the internal passage of the discharge outlet, and an annular connector portion connected to the central body and configured to releasably engage an exterior of the discharge outlet, the central body defining an internal channel within the central body that is in fluid communication with the interior cavity of the conical body when the connector is attached to the discharge outlet. 1. A connector assembly for a fluid delivery system , comprising:a conical body defining an interior cavity and a discharge outlet, the discharge outlet defining an internal passage in fluid communication with the interior cavity; anda connector removably attached to the discharge outlet, the connector comprising a central body configured to be at least partially positioned within the internal passage of the discharge outlet, and comprising an annular connector portion connected to the central body and configured to releasably engage an exterior of the discharge outlet, the central body defining an internal channel within the central body that is in fluid communication with the interior cavity of the conical body when the connector is attached to the discharge outlet.2. The connector assembly according to claim 1 , wherein the central body of the connector defines a distal portion that extends beyond a distal end of the discharge outlet and a proximal portion that is positioned within the internal passage of the discharge outlet when the connector is attached to the discharge outlet.3. The connector assembly according to claim 1 , wherein a proximal portion of the central body of the connector is contoured to correspond ...

QUICK DISCONNECT CONNECTOR ASSEMBLY

A quick-disconnect connector assembly includes a housing having a bore that extends up to but not through a first end of the housing. The connector assembly also includes a proximity switch disposed within the bore, and the proximity switch includes a switch body, a first contact member, and a second contact member. A portion of each of the first and second contact members extends from the switch body towards a second end of the housing. In a first switch position, a contact of a displaceable switching assembly is in contact with the first contact member, and in a second switch position, the contact is in contact with the second contact member. The connector assembly also includes an external connection assembly including a first pin that is electrically coupled to the first contact member and a second pin that is electrically coupled to the second contact member. 1. A quick-disconnect connector assembly comprising:a housing that extends along a longitudinal axis from a first end to a longitudinally-opposite second end, the housing including one or more interior surfaces that cooperate to define a bore that extends from the second end to a point adjacent to the first end such that the bore does not extend through the first end of the housing, wherein the bore includes a first bore portion; a switch body extending along a body longitudinal axis, the switch body having a first end disposed adjacent to the first end of the housing and a longitudinally-opposite second end; and', 'a first contact member and a second contact member, each of the first and second contact members having a first end and a longitudinally-opposite second end, the second end being disposed within the switch body and the first end being disposed external to the switch body, wherein a portion of each of the first and second contact members extends from the second end of the switch body towards the second end of the housing,', 'wherein in a first switch position, a contact of a displaceable ...

VIAL CONTAINER WITH COLLAR CAP

Vial containers including a collar which is attached to a vial or incorporated into a vial cap, a cap designed to receive a portion of the collar while covering the vial, and a container designed to receive a portion of the collar and encase the body of the vial are described herein. The collar, generally, includes a means for reversibly attaching to the cap and container. 1. A vial container comprising:a collar;a container configured to receive a portion of the collar and to fixedly attach to a portion of the collar;a cap configured to receive a portion of the collar and to removeably attach to the collar.2. The vial container of claim 1 , wherein the collar comprises a first attachment means for facilitating an attachment with the container.3. The vial container of claim 2 , wherein the first attachment means is selected from the group consisting of a flex-ring claim 2 , threads claim 2 , a crimped portion claim 2 , attachment pins claim 2 , and combinations thereof.4. The vial container of claim 1 , wherein the collar comprises a second attachment means for facilitating an attachment with the cap.5. The vial container of claim 4 , wherein the second attachment means is selected from the group consisting of a flex-ring claim 4 , threads claim 4 , a crimped portion claim 4 , attachment pins claim 4 , and combinations thereof.6. The vial container of claim 1 , wherein the collar comprises one or more of a lower groove and upper groove or combinations thereof.7. The vial container of claim 1 , wherein the collar comprises a magnetic material disposed in a lower groove claim 1 , an upper groove claim 1 , or a combination thereof.8. The vial container of claim 1 , wherein the collar comprises a vial groove on an inner surface of the collar.9. The vial container of claim 8 , further comprising a spring disposed in the vial groove.10. The vial container of claim 1 , wherein the collar comprises a upper flange providing an upper opening on the collar.11. The vial ...

MULTIPLE COMPARTMENT SYRINGE

Various syringe systems are disclosed. One illustrative syringe system may include a syringe body having a hollow lumen and a distal end. The syringe body may be configured to house a plurality of fluids therein. A first plunger may be positioned in the hollow lumen of the syringe body, forming a first seal with an inner wall of the syringe body, and forming a first compartment between the first plunger and the distal end of the syringe. A second plunger may be positioned proximal to the first plunger in the hollow lumen of the syringe body, forming a second seal with the inner wall of the syringe body, and forming a second compartment between the first plunger and the second plunger. A plurality of recesses may be disposed about the inner wall of the syringe body near the distal end of the syringe body. 1. A syringe system comprising:a syringe body comprising a hollow lumen and a distal end, the syringe body being configured to house a plurality of fluids therein;a first plunger positioned in the hollow lumen of the syringe body, forming a first seal with an inner wall of the syringe body, and forming a first compartment between the first plunger and the distal end of the syringe;a second plunger positioned proximal to the first plunger in the hollow lumen of the syringe body, forming a second seal with the inner wall of the syringe body, and forming a second compartment between the first plunger and the second plunger; anda plurality of recesses disposed about the inner wall of the syringe body near the distal end of the syringe body.2. The syringe system of claim 1 , further comprising a connection piece positioned between the first plunger and the second plunger.3. The syringe system of claim 2 , wherein the connection piece is a filament.4. The syringe system of claim 1 , wherein the syringe body further comprises an open proximal end having a finger guard affixed thereto.5. The syringe system of claim 1 , further comprising a piston connected to the second ...

Fluid Mixing Control Device for a Multi-Fluid Delivery System

A fluid delivery system for use in medical procedures includes multiple fluid pump devices to deliver multiple injection fluids to a patient. The system includes a control unit controlling the fluid pump devices. An interactive visual display may be provided and electronically linked to the control unit so a user may select discrete mixture ratios of the first and the second of the multiple injection fluids to be delivered to the patient. A manual control device is operatively associated with the fluid pump devices and includes a housing and an actuator associated with the housing. Actuation of the actuator controls discrete flow rates of the selected discrete mixture ratio of the first and the second of the multiple injection fluids to the patient. 1. A fluid delivery system for use in medical procedures to deliver multiple injection fluids to a patient , comprising:a first pump device for delivering a first of the multiple injection fluids to the patient;a second pump device for delivering a second of the multiple injection fluids to the patient;a control unit controlling the first pump device and the second device;an interactive visual display electronically linked to the control unit for a user to select discrete mixture ratios of the first and the second of the multiple injection fluids to be delivered to the patient; and a housing; and', 'an actuator associated with the housing and controlling discrete flow rates of the selected discrete mixture ratios of the first and the second of the multiple injection fluids to the patient; and, 'a manual control device operatively associated with the first pump device and the second pump device, comprisingwherein selection of a discrete mixture ratio by a user initiates an output signal to the control unit to deliver the first and the second of the multiple injection fluids in the selected discrete mixture ratio of the first and the second of the multiple injection fluids to the patient, andwherein actuation of the ...

INTELLIGENT AND CONFIGURABLE FLUID DELIVERY SYSTEM AND METHODS FOR ITS USE

A configurable fluid delivery system and methods for its use are disclosed. The system may include one or more control units, fluid delivery units, fluid actuator units, and disposable units. Data sources and sensors on each of the delivery units, actuator units, and disposable units may provide data to the control unit, thereby identifying the components along with the manner in which they may be configured. The control unit may notify a user regarding the status of any one or more of the delivery, actuator, and disposable units to indicate their appropriateness for delivering a fluid according to one or more selected procedures and protocols. Also disclosed are methods by which the configurable fluid delivery unit may provide data to a user to assist the user in assembling and testing a particular fluid delivery configuration for a specific use. 1. A configurable fluid delivery system , the system comprising:a fluid delivery unit comprising at least one delivery unit data source;a fluid actuator unit in reversible mechanical communication with the fluid delivery unit, wherein the fluid actuator unit comprises an actuator unit data source; and a computing device in reversible data communication with at least one of the fluid delivery unit and the fluid actuator unit, and', 'a non-transitory, computer-readable storage medium in operable communication with the computing device; and', 'an output device in operable communication with the computing device;, 'a control unit comprising receive delivery unit data from the delivery unit data source and actuator unit data from the actuator unit data source,', 'determine a mechanical compatibility status between the fluid delivery unit and the fluid actuator unit based, at least in part, on the delivery unit data and the actuator unit data,', 'transmit, to the output device, an output related to the mechanical compatibility status,', 'determine a communication integrity status between two or more of: the fluid delivery unit, ...

Interventional catheter assemblies and control components for interventional catheter assemblies

Interventional catheter assemblies and components providing improved operational control of interventional catheters and/or operating heads of interventional catheters are provided. In general, controllers incorporate at least two operator selectable control features for controlling operation of the interventional catheter and/or an operating head, and are housed independently of the interventional catheter operating systems and other control systems, which may be provided in a housing located or locatable at a proximal region of the interventional catheter. The controller may be both dockable in and removable from the housing, and is operable in both a docked condition and a removed condition, providing flexibility and mobility in operational control during an interventional procedure.

BULK FLUID SOURCE INJECTOR SYSTEMS

An injector system including a docking station and a cassette and various transfer devices for transferring fluid from a bulk fluid container to a reservoir in the cassette are described herein along with methods for using such devices and systems to inject fluid from the bulk fluid container into a patient. 1. A transfer device comprising:a spike;a port connector;a transfer tube operably connected to the spike and the port connector; anda guard enclosing the spike, port connector and transfer tube.2. The transfer device of claim 1 , further comprising an air vent and a vent tube or secondary passage aligned with the spike.3. The transfer device of claim 2 , further comprising a check valve claim 2 , air filter claim 2 , or combination thereof operably connected to the air vent.4. The transfer device of claim 1 , wherein the port connector is retractable an operably connected to a spring.5. The transfer device of claim 4 , wherein the retractable port connector block flow of fluid through the transfer tube when in extended position.6. The transfer device of claim 4 , further comprising a first transfer tube operably connected to the spike and a second transfer tube enclosed within the port connector.7. The transfer device of claim 1 , further comprising a septum disposed over a distal portion of the transfer tube.8. A cassette for transporting fluid from a source to a patient comprising:a cassette body;one or more reservoirs dispose within the cassette body;at least one inlet port operably connected to each of the one or more reservoirs;at least one fluid passage operably connected to each of the one or more reservoirs; andan outlet port at a convergence of at least one fluid passage.9. The cassette of claim 8 , further comprising at least one air vent operably connected to each of the one or more reservoirs.10. The cassette of claim 8 , further including a waste reservoir.11. The cassette of claim 8 , further comprising a fluid detector operably connected to at ...

CONSTANT FORCE SYRINGE

Various syringe systems are disclosed. One such syringe system may include a body having a hollow lumen and a distal end, a vacuum chamber disposed within the hollow lumen of the syringe body, a first plunger connected to a distal portion of the vacuum chamber, the first plunger forming a first seal against an inner surface of the syringe body and defining a fluid delivery volume between the first plunger and the distal end of the syringe body, a second plunger disposed within the vacuum chamber, the second plunger forming a second seal against an inner surface of the vacuum chamber and defining a proximal and distal volume compartments within the vacuum chamber, and a piston affixed to the second plunger, the piston configured to move the second plunger within the vacuum chamber, thereby altering a volume of the proximal volume compartment and a volume of the distal volume compartment. 1. A syringe system comprising:a syringe body comprising a hollow lumen and a distal end, the syringe body being configured to house a fluid therein;a vacuum chamber disposed within the hollow lumen of the syringe body;a first plunger connected to a distal portion of the vacuum chamber within the hollow lumen of the syringe body, the first plunger forming a first seal against an inner surface of the syringe body and defining a fluid delivery volume between the first plunger and the distal end of the syringe body;a second plunger disposed within the vacuum chamber, the second plunger forming a second seal against an inner surface of the vacuum chamber and defining a proximal volume compartment and a distal volume compartment within the vacuum chamber; anda piston affixed to the second plunger and extending proximally out of the vacuum chamber, the piston configured to move the second plunger within the vacuum chamber, thereby altering a volume of the proximal volume compartment and a volume of the distal volume compartment.2. The syringe system of claim 1 , further comprising a bore ...

FLUID EFFICIENT SPIKE

Spikes, spike and tubing sets and fluid administrations systems are disclosed. A fluid administration system may include a fluid container having a septum and containing a fluid, a spike, and a flexible tube. The spike may include a hollow access tube extending from a proximal end to a distal end of the spike, a platform surrounding the hollow access tube at a location between the distal and proximal ends, and a sharp tip-end at the distal end. The access tube has a central bore and a sidewall, each extending from the proximal to the distal end. The access tube may include at least one opening extending from the central bore to the sidewall and located between the platform and the sharp tip-end. The flexible tube is configured to connect to the access tube and to deliver fluid from the access tube to a fluid administration location. 1. A spike for fluid administration , the spike comprising:a hollow access tube extending from a proximal end of the spike to a distal end of the spike;a platform surrounding the hollow access tube at a location between the distal end and the proximal end; anda sharp tip-end located at the distal end of the spike,wherein the hollow access tube has a central bore and a sidewall, each extending from the proximal end to the sharp tip-end,wherein the hollow access tube comprises at least one opening extending from the central bore to the sidewall and located between the platform and the sharp tip-end.2. The spike of claim 1 , wherein the at least one opening comprises one or more holes.3. The spike of claim 2 , wherein the one or more holes comprise a plurality of holes claim 2 , wherein at least a portion of a first hole overlaps with at least a portion of a second hole in a cross-sectional plane.4. The spike of claim 2 , wherein the one or more holes comprise a plurality of holes in a plurality of columns claim 2 , wherein at least a portion of each hole in a first column of the plurality of columns overlaps with at least a portion of a ...

MEDICAL FLUID INJECTOR

Systems and methods for intelligently delivering fluid to a targeted tissue. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range. If the one or more sensed feedback parameters are not within the acceptable range, the systems and methods may include determining an adjusted velocity for the plunger necessary to adjust the pressure of the fluid in the pump so that the one or more sensed feedback parameters move within the acceptable range and directing the pump to distribute the fluid at the adjusted velocity. 1. A system for intelligently delivering fluid to a targeted tissue , the system comprising:a pump configured to contain a volume of fluid at a pressure;a processor;an intracorporeal sensing system in operable communication with the processor; and direct the pump to distribute the fluid to the targeted tissue at an initial velocity;', 'receive one or more signals from the intracorporeal sensing system, wherein the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue;', 'determine whether the one or more sensed feedback parameters are within an acceptable range;', 'if the one or more sensed feedback parameters are not within the acceptable range, determine an adjusted velocity; and', 'direct the pump to distribute the fluid at the adjusted velocity., 'a non-transitory, processor-readable storage medium in communication with the processor, wherein the non-transitory, processor-readable storage medium contains one or more programming instructions that, when executed, cause the processor to2. The system of claim 1 , further comprising one or more programming instructions ...

CATHETER SYSTEM

A multi-station hydrodynamic catheter includes an outer catheter having a first lumen, the outer catheter having a plurality of orifice stations positioned along a portion of the outer catheter, where each orifice station includes one or more orifices extending from an outer catheter external surface to the first lumen. The multi-station hydrodynamic catheter includes an inner catheter having a second lumen, the inner catheter movable within the first lumen and includes at least one emanator, where the at least one emanator includes one or more fluid delivery ports extending from an inner catheter external surface to the second lumen. 1. A catheter system comprising: an outer catheter having a first lumen, the outer catheter having a plurality of orifice stations positioned along a portion of the outer catheter, wherein each orifice station includes one or more orifices extending from an outer catheter external surface to the first lumen; and', the inner catheter movable within the first lumen between a first orifice station and a second orifice station of the plurality of orifice stations,', 'wherein at the first orifice station, the one or more fluid delivery ports of the emanator are in fluid communication with the one or more orifices of the first orifice station of the plurality of orifice stations, and at the second orifice station, the one or more fluid delivery ports of the emanator are in fluid communication with the one or more orifices of a second orifice station of the plurality of orifice stations, the second orifice station positioned distally relative to the first orifice station, and', 'wherein the one or more orifices at the first orifice station are configured to generate a first fluid jet and the one or more orifices at the second orifice station are configured to generate a second fluid jet distal to the first fluid jet., 'an inner catheter having a second lumen, the inner catheter movable within the first lumen and includes at least one emanator ...

HYDRODYNAMIC ECCENTRICALLY PIVOTING CATHETER

A hydrodynamic catheter includes a catheter body with a catheter lumen and an infusion tube extending within the catheter body, the infusion tube configured for coupling with a fluid source near the catheter proximal portion. An inflow orifice and an outflow orifice are positioned at locations along a catheter body perimeter. A fluid jet emanator is in fluid communication with the infusion tube, where the fluid jet emanator includes one or more jet orifices configured to direct one or more fluid jets through the catheter lumen from near the inflow orifice toward the outflow orifice. A pivot cylinder located along the catheter body perimeter is positioned distal relative to one or more of the fluid jet emanator, the inflow orifice, or the outflow orifice. 1. A hydrodynamic catheter comprising:a catheter body with a catheter lumen extending from a proximal catheter portion to a distal catheter portion;an infusion tube extending within the catheter body from the catheter proximal portion toward the catheter distal portion, the infusion tube is configured for coupling with a fluid source near the catheter proximal portion;an inflow orifice at a first location along a catheter body perimeter;an outflow orifice at a second location along the catheter body perimeter spaced from the first location;a fluid jet emanator in fluid communication with the infusion tube, the fluid jet emanator including one or more jet orifices, the one or more jet orifices configured to direct one or more fluid jets through the catheter lumen from near the inflow orifice toward the outflow orifice; anda pivot cylinder at a third location along the catheter body perimeter, the third location distal relative to one or more of the fluid jet emanator, the inflow orifice, or the outflow orifice; and in the first rotated position the inflow and outflow orifices are directed in a first direction, and the inflow and outflow orifices are positioned in close proximity to a first portion of a vessel, and', ...

CATHETER SYSTEM WITH BALLOON-OPERATED FILTER SHEATH AND FLUID FLOW MAINTENANCE

A catheter system includes an inflatable structural balloon and collapsible filter. The collapsible filter is deployable into an expanded configuration using the inflatable distal balloon. In the expanded configuration, one or more flow cells are formed between inflated portions of the balloon to provide continuous fluid flow between proximal and distal ends of the structural balloon. In the expanded configuration, the filter is configured to prevent particulates (e.g., dislodged thrombus, or other particulate material) from migrating beyond the filter. In the expanded configuration, the inflated structural balloon biases a perimeter of the filter toward or against a subject vessel wall. 1. A catheter system with inflatable balloon and collapsible filter , the catheter system comprising:a catheter tube having a proximal portion and a distal portion;an inflatable structural balloon, coupled to the catheter tube near the distal portion; and in the collapsed configuration, the filter sheath is collapsed around the catheter tube, and', 'in the expanded configuration, the filter sheath is expanded according to inflation of the structural balloon, and the structural balloon includes one or more inflated portions, wherein one or more flow cells extend along the one or more inflated portions and are configured to provide continuous fluid communication between proximal and distal ends of the structural balloon., 'a filter sheath coupled to the structural balloon, the filter sheath having a collapsed configuration and an expanded configuration, wherein2. The catheter system of claim 1 , wherein the one or more inflated portions includes a plurality of inflated portions having one or more engagement locations coupled with the filter sheath claim 1 , the one or more engagement locations at an outer edge of the structural balloon claim 1 , and in the expanded configuration the one or more engagement locations biases the filter sheath toward a shape corresponding to the outer ...

Adjustable orthotic foot brace and method for adjusting a foot brace

The orthotic foot brace for a person wearing a footwear generally has: a lower leg holder securable to a lower leg of the person for use, a lower leg strut connected to the lower leg holder and extending downwardly towards the footwear during use; a foot strut structurally connected to the lower leg strut and having at least one side portion, each side portion extending forwardly along a respective side of the footwear and extending outwardly along a respective side of the footwear; an instep strut provided in the form of an extension of the foot strut along a long axis of the footwear, the instep strut having a distal portion securable to the footwear, and at least a proximal portion being slidably connected to the foot strut in a manner to allow adjusting the extension distance of the distal portion to a selected position.

TRACEABLE METALLIC PRODUCTS AND METALLIC SUPPORT FOR NANOSTORAGE

The invention relates to traceable metallic products, methods of uses and methods of making same. The metallic products may be made traceable for integrity purposes, identification purposes, counterfeit avoidance and the like. The invention also relates to metallic supports for nanostorage of various compounds and samples. 1. A traceable metallic product , wherein said metallic product comprises a porous surface layer formed by anodization , and wherein said porous surface layer comprises at least one traceable biological compound.2. (canceled)3. The traceable metallic product of claim 1 , wherein said at least one traceable biological compound is selected from the group consisting of nucleic acids claim 1 , peptidic molecules claim 1 , lipids claim 1 , mono and polysaccharides claim 1 , hormones claim 1 , vitamins claim 1 , and derivatives thereof.4. (canceled)5. The traceable metallic product of claim 1 , wherein said at least one traceable biological compound is carried in nanopores of the porous surface layer claim 1 , and wherein said at least one traceable compound is recoverable from said porous surface layer for detection claim 1 , identification and/or utilization purposes.6. (canceled)7. The traceable metallic product of claim 1 , wherein said traceable metallic product consists of a metallic support for nanostorage of compound and samples.8. The traceable metallic product of claim 1 , wherein said porous surface layer is sealed.9. The traceable metallic product of claim 1 , wherein said porous surface layer further comprises an electrodeposit of at least one metal selected from the group consisting of silver claim 1 , gold claim 1 , copper claim 1 , nickel claim 1 , zinc claim 1 , tin claim 1 , cadmium claim 1 , palladium and platinum.10. The traceable metallic product of claim 1 , wherein said traceable metallic product consists of a traceable piece of aluminum comprising a porous surface layer formed by anodization claim 1 , and wherein said porous ...

VALVE SIGNATURE DIAGNOSIS AND LEAK TEST DEVICE

A valve signature diagnosis and leak testing device includes a spool valve operatively connected to a pilot valve, the pilot valve being configured to position the spool valve to one of an open position and a closed position. A blocker valve is fluidly connected to a control fluid outlet of the spool valve. An electrical module is operatively connected to the pilot valve, a supply of control fluid, and the blocker valve, the electrical module being capable of sending pulsed electrical signals to the pilot valve and the blocker valve to selectively position the spool valve and the blocker valve to an open or closed position.

Patient infusion system for use with MRI

This invention relates generally to the field of Magnetic Resonance Imaging (MRI) systems for generating diagnostic images of a patient's internal organs and more particularly, this invention relates to improved MRI systems with decreased interference between the magnetic field used for producing diagnostic images and the magnetic fields generated by the electric motors used for driving the pistons of the contrast media injectors. Additionally, the system employs an improved communication link between an externally located system controller and the injection head control unit located within the electromagnetic isolation barrier which defines the magnetic imaging room.

Powered injector systems and injector control

An injector system includes a powered injector, a pressurizing chamber in operative connection with the powered injector, a fluid path in fluid connection with the pressurizing chamber, and a manual control in fluid connection with the fluid path. The manual control includes at least one actuator for controlling the injector through application of force by an operator. The actuator provides tactile feedback of pressure in the fluid path to the operator via a fluid connection with the fluid path. An injection system for use in angiography includes a source of saline, a pump in fluid connection with the source of saline to pressurize the saline, a saline valve in fluid connection via a first port thereof with an outlet of the pump, a first connector in fluid connection with a second port of the saline valve, a source of contrast, a contrast valve in fluid connection with the source of contrast via a first port of the contrast valve, a powered injector in fluid connection with a second port of the contrast valve, a second connector in fluid connection with a third port of the contrast valve, and a pressure isolation mechanism. The pressure isolation mechanism has a first port in fluid connection with the second connector, a second port in fluid connection with a patient catheter, and a third port in fluid connection with the first connector. The pressure isolation mechanism further includes a valve having a first state and a mutually exclusive second state—the first state occurring when the second and third ports are connected and the first and third ports are connected, and the second state occurring when the first and second ports are connected and the first and third ports are disconnected. The valve is preferably normally biased to the first state and is switchable to the second state when fluid pressure from the powered injector reaches a predetermined pressure level. The system further includes a pressure transducer in fluid connection with the third port of the ...

Systems and methods for operating interventional catheters using a common operating console and adaptive interface components

Interventional catheter assemblies, operating systems and adaptive interface components allow operation of a variety of interventional catheter assemblies, including infusion catheters, aspiration catheters and interventional catheters that provide both infusion and aspiration, using a common control console housing infusion and aspiration systems. Control instructions for operating the interventional catheter assembly and authentication protocols for verifying system matches and operating conditions maybe encoded in hardware, firmware or software, such as a memory or storage device, provided in the interventional catheter assembly or in a discrete adaptive interface component. Adaptive components such as tubing cassettes routing aspiration and/or infusion tubing in a predetermined configuration to mate with aspiration and infusion systems on a control console are also provided.

Injection system, pump system for use therein and method of use of pumping system

The present invention provides an injection system and a pump system for use therein for pressurizing a liquid medium for injection into a patient. In general, the pump system comprises a pressurizing unit having at least one chamber. Each chamber has disposed therein a pressurizing mechanism to pressurize liquid medium within the chamber. Preferably, the pressurizing mechanism positively displaces the liquid medium through generally linear motion of the pressurizing mechanism within the chamber. Through reciprocating linear motion of the pressurizing mechanism (for example, a piston), the liquid medium is alternatively drawn into the chamber from a source of liquid medium (for example, a container) and forced out of the chamber under a desired pressure. Each chamber comprises an inlet port and an outlet port. The pump system also preferably comprises an inlet port check valve which allows the liquid medium to flow into the chamber through the inlet port, but substantially prevents the liquid medium from flowing out of the chamber through the inlet port. Likewise, the pump system preferably comprises an outlet port check valve which allows pressurized liquid medium to flow out of the chamber through the outlet port, but substantially prevents the liquid medium from flowing into the chamber through the outlet port. Each inlet port is connected to a source of liquid medium. Each outlet port is connected to a common outlet line or channel leading to the patient.

Fluid delivery system having a plurality of resilient pressurizing chambers

A fluid delivery system includes a fluid container, two or more pressurizing chambers in fluid connection with the fluid container, a drive mechanism in operative connection with the two or more pressurizing chambers to pump fluid from the fluid container and an outlet in fluid connection with the two or more pressurizing chambers. Each of the two or more pressurizing chambers is formed from a flexible, resilient material that is adapted to be compressed to pressurize fluid therewithin.

System and method for proportional mixing and continuous delivery of fluids

A system and method for mixing and delivering fluids such as contrast media and saline is disclosed including at least two fluid sources, a pump, a joining fluid path connecting the at least two fluid sources to an inlet to the pump, and a valve device in the fluid path upstream of the pump. The valve device includes an actuator adapted to restrict flow in at least one of respective fluid lines connecting the at least two fluid sources to the pump inlet. A patient interface device may be associated with an outlet of the pump. The valve device actuator is generally adapted to restrict the flow in at least one of the respective fluid lines such that a positional change in valve device actuator position provides a change in fluid mixture ratio of the fluids from the at least two fluid sources to the pump inlet.

Injection system, pump system for use therein and method of use of pumping system

The present invention provides an injection system and a pump system for use therein for pressurizing a liquid medium for injection into a patient. In general, the pump system comprises a pressurizing unit having at least one chamber. Each chamber has disposed therein a pressurizing mechanism to pressurize liquid medium within the chamber. Preferably, the pressurizing mechanism positively displaces the liquid medium through generally linear motion of the pressurizing mechanism within the chamber. Through reciprocating linear motion of the pressurizing mechanism (for example, a piston), the liquid medium is alternatively drawn into the chamber from a source of liquid medium (for example, a container) and forced out of the chamber under a desired pressure. Each chamber comprises an inlet port and an outlet port. The pump system also preferably comprises an inlet port check valve which allows the liquid medium to flow into the chamber through the inlet port, but substantially prevents the liquid medium from flowing out of the chamber through the inlet port. Likewise, the pump system preferably comprises an outlet port check valve which allows pressurized liquid medium to flow out of the chamber through the outlet port, but substantially prevents the liquid medium from flowing into the chamber through the outlet port. Each inlet port is connected to a source of liquid medium. Each outlet port is connected to a common outlet line or channel leading to the patient.

Methods of conducting thrombectomy procedures and deploying a thrombectomy catheter

Methods of conducting thrombectomy procedures and deploying a thrombectomy catheter are disclosed. A thrombectomy procedure is conducted with a thrombectomy catheter deployment system. A drive unit configured to operate an infusion pump is provided. The drive unit is operable according to one or more operating modes. A preconnected and consolidated pump and catheter assembly configured for loading in the drive unit is also provided. The assembly is separate from the drive unit prior to loading. The infusion pump and a catheter of the assembly are in communication prior to loading. The assembly provides one or more digital instructions to the drive unit. The drive unit is operable according to the one or more operating modes referenced by the one or more digital instructions. The assembly is loaded into the drive unit, and the drive unit is engaged to the infusion pump for operation of the infusion pump.

Thrombectomy catheter deployment system

A thrombectomy catheter deployment system which greatly simplifies setup procedures and operation of a thrombectomy catheter includes a stand alone drive unit and a disposable pump/catheter assembly which is manually placed into a carriage assembly in the drive unit. The pump/catheter assembly has a plurality of preconnected components including tubular structure and a thrombectomy catheter connected thereto and is transported into or out of the interior of the drive unit for automatic high pressure pump piston head engagement or disengagement with a reciprocating linear actuator and for automatic engagement or disengagement of an effluent waste tube with a roller pump. A barcode reader senses specific operational data pertaining to an individual pump and provides an interface for operation of the reciprocating linear actuator. A bubble trap incorporated for effective debubbling of saline solution is closely coupled to an insert molded pump having an improved valve arrangement. A spiked bag with large tubing is incorporated for bubble-free transfer of saline.

Thrombectomy Catheter Deployment System

A thrombectomy catheter deployment system which greatly simplifies setup procedures and operation of a thrombectomy catheter includes a stand alone drive unit and a disposable pump/catheter assembly which is manually placed into a carriage assembly in the drive unit. The pump/catheter assembly has a plurality of preconnected components including tubular structure and a thrombectomy catheter connected thereto and is transported into or out of the interior of the drive unit for automatic high pressure pump piston head engagement or disengagement with a reciprocating linear actuator and for automatic engagement or disengagement of an effluent waste tube with a roller pump. A barcode reader senses specific operational data pertaining to an individual pump and provides an interface for operation of the reciprocating linear actuator. A bubble trap incorporated for effective debubbling of saline solution is closely coupled to an insert molded pump having an improved valve arrangement. A spiked bag with large tubing is incorporated for bubble-free transfer of saline.

Injection system, pump system for use therein and method of use of pumping system

The present invention provides an injection system and a pump system for use therein for pressurizing a liquid medium for injection into a patient. In general, the pump system (10) comprises a pressurizing unit (15) having at least one chamber. Each chamber (20) has disposed therein a pressurizing mechanism (70) to pressurize liquid medium within the chamber. Preferably, the pressurizing mechanism positively displaces the liquid medium through generally linear motion of the pressurizing mechanism within the chamber. Through reciprocating linear motion of the pressurizing mechanism (for example, a piston), the liquid medium is alternatively drawn into the chamber from a source of liquid medium (for example, a container) and forced out of the chamber under a desired pressure. Each chamber comprises an inlet port (25) and an outlet port (30). The pump system also preferably comprises an inlet port check valve (40) which allows the liquid medium to flow into the chamber through the inlet port, but substantially prevents the liquid medium from flowing out of the chamber through the inlet port. Likewise, the pump system preferably comprises an outlet port check valve (40) which allows pressurized liquid medium to flow out of the chamber through the outlet port, but substantially prevents the liquid medium from flowing into the chamber through the outlet port. Each inlet port is connected to a source of liquid medium (50). Each outlet port is connected to a common outlet line or channel (60) leading to the patient.

Programmable injector control

A fluid injection arrangement, in the context of patient imaging systems, in which phases of contrast medium injection and flushing medium injection can be freely and selectably ordered so as to make available to the operator and patient a vast array of possible protocols that has hitherto been essentially unattainable. Also contemplated is the use of a “hold” phase, involving an indefinite pause between phases of a protocol, in connection with such imaging systems. Further contemplated is the use of a “pause” phase in which a pause of fixed duration is pre-programmed into the protocols of MRI injector systems.

Method of substituting a first fluid delivery device with a second fluid delivery device

A method of substituting an MRI incompatible pump for delivering fluid to a patient with an MRI compatible pump, both pumps being microprocessor controlled. The first pump operates upon administration tubing for pumping fluid from a source thereof to the patient. The method includes the steps of: providing the second pump to be substituted for the first pump; providing second tubing having a portion thereof that is operable to function with the second pump; connecting the second tubing to the administration tubing to establish an altered fluid path from the source to the patient, the altered path including portions of both the administration and second tubing; placing the second pump for operation upon the second tubing to enable the second pump to pump the fluid through the altered path according to programming thereof; and disconnecting the first pump from the administration tubing before bringing the patient into the MRI environment.

Processor-controlled angiographic injector device

An angiographic injector device for use in x-ray photography for delivering contrast media to a patient at controlled rates and pressures. A processor elicits injection parameters from an operator or a pre-programmed injection module, and on the basis of the injection parameters, calculates appropriate control signals for use in a closed-loop servo system to actuate the plunger of a syringe containing the contrast media. Injection parameters includes flow rate, volume, duration, pressure limit and rise-fall time of flow rate. The device also includes control circuits for inhibiting the injection device in response to a contrast media pressure limit, failure in the processor or injection control system, or upon reaching a predetermined volume of injected media. A mechanical stop member cooperates with the control circuit for blocking movement of the syringe plunger upon reaching the predetermined injected volume. Further, the device includes a self-test feature for checking the status of operational components thereof and a self-calibration feature for calibrating the servo system and position monitors. To improve reliability and to provide immunity from data corruption due to line power interruption, injection parameters are stored in battery-powered primary and secondary memories, and are compared and verified prior to an injection. To assist in coordinating an injection in synchronism with cardiac activity, the device monitors the ECG waveform of the patient's heart and injects a small bolus of contrast media at a given interval, such as the distolic interval. An interface also is provided for providing remote transfer of status and control information with the angiographic injector device.

Medical syringe

Data communication and control for medical imaging systems

A system for producing a contrast-enhanced medical image of a patient includes a source of a contrast or enhancement medium, a pressurizing unit in fluid connection with the source of contrast or enhancement medium, an energy source operable to apply energy to a region of the patient, an imaging unit providing a visual display of an internal view of the patient based upon a signal resulting from the energy applied to the region of the patient, and a control unit. In an embodiment, the signal is affected by a condition of the contrast or enhancement medium in the patient. To control the procedures, the control unit adjusts the condition of the contrast or enhancement medium in the patient based upon the signal. A communication interface preferably enables information between an injector subsystem and an imaging subsystem.

Injector providing drive member advancement and engagement with syringe plunger, and method of connecting a syringe to an injector

An injector for injecting a fluid from a syringe (which syringe includes a body, a plunger moveably positioned within the body, and an encoding device providing syringe information)r includes a housing, a motor disposed within the housing, a controller operably associated with the motor, a sensor operably associated with the controller and operable to read the encoded syringe information provided by the encoding device when the syringe is attached to the injector, a drive member disposed in the housing and powered by the motor, the drive member operable to automatically advance and engage the plunger when the sensor reads the syringe information provided by the encoding device, and a plunger engagement detection device operably associated with the controller and operable to indicate when the drive member of the injector has engaged the plunger of the syringe.

Injectors, injector systems and injector control

An injector for use in injecting a fluid in a medical injection procedure includes a drive mechanism to pressurize the fluid; a sensor to measure a variable that is proportional to fluid pressure (that is, a direct or indirect measurement of fluid pressure); and a pressure monitor (for example, including hardwired circuitry and/or software) in communication with the sensor and the drive mechanism to stop the injection procedure when the sensor measures a value of the variable that corresponds to a pressure hazard limit. Peferably, the pressure monitor further limits power input to the drive mechanism to a power limit once the variable reaches a value that corresponds to a power limiting pressure that is below the pressure hazard limit.

Injection system and pumping system for use therein

The present invention provides a number of pumping systems and injection systems particularly useful for injecting a liquid medium into a patient. In general, the pumping systems comprise a removable pumping unit. The removable pumping unit includes means for pressurizing the liquid medium via the rotational displacement of the liquid medium. The present invention also provides a pumping system comprising a pumping unit for pressurizing the liquid medium and a feedback-controlled drive means in connection with the pumping unit for providing a controlled powered drive to the pumping unit. The pumping system further comprises a flow meter for measuring the flow rate of the pressurized liquid medium exiting the pumping system and control means in communicative connection with the drive means for providing a control signal to control the powered drive provided to the pumping unit. The control means is suitable to receive a feedback signal from the flow meter corresponding to the flow rate of the pressurized liquid medium exiting the pumping unit. The control signal provided to the drive means is a function of the feedback signal.

Injection system having a pressure isolation mechanism and/or a handheld controller

An injector system includes a powered injector, a pressurizing chamber in operative connection with the powered injector, a fluid path in fluid connection with the pressurizing chamber, and a manual control in fluid connection with the fluid path. The manual control includes at least one actuator for controlling the injector through application of force by an operator. The actuator provides tactile feedback of pressure in the fluid path to the operator via a fluid connection with the fluid path. An injection system for use in angiography includes a source of saline, a pump in fluid connection with the source of saline to pressurize the saline, a saline valve in fluid connection via a first port thereof with an outlet of the pump, a first connector in fluid connection with a second port of the saline valve, a source of contrast, a contrast valve in fluid connection with the source of contrast via a first port of the contrast valve, a powered injector in fluid connection with a second port of the contrast valve, a second connector in fluid connection with a third port of the contrast valve, and a pressure isolation mechanism.

Fluid delivery system including a fluid path set and a check valve connector

A fluid path for use in a fluid delivery system is described. The fluid path may have a connecter member having a lumen, a luer member connected to the lumen, and an annular member around the luer member. The fluid path may further have a check valve in the lumen to limit fluid flow in one direction. The check valve may have a deformable stopper element and a retaining sleeve disposed in the lumen of the connecter member. The retaining sleeve may have a central bore and a distal end against which the stopper element sits to prevent fluid flow through the lumen until a sufficient fluid pressure is present to deform the stopper element and unseat the stopper from the retaining sleeve. One or more grooves may be present in the receiving cavity. The fluid path may further have a drip chamber, a second tubing section, and a spike.

Fluid delivery system, fluid path set, sterile connector and improved drip chamber and pressure isolation mechanism

The fluid path set is intended for use in a fluid delivery system. The fluid path set includes a multi-patient use section adapted for connection to a syringe used in the fluid delivery system, and to a source of fluid, such as contrast media, to be loaded into the syringe. The fluid path set further includes a per-patient use section that is removably connected to the multi-patient use section. A connector removably connects the multi-patient use section and the per-patient use section. A drip chamber is provided between the source of fluid and the syringe, and includes a projection for determining a level of fluid in the drip chamber. The per-patient use section includes a pressure isolation mechanism. The pressure isolation mechanism includes a lumen, a pressure isolation port, and a valve member with a biasing portion that biases the valve member to a normally open position.