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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 4. Отображено 4.
02-09-2009 дата публикации

Novel juvenile hormone synthesis inhibitor-phenylpropyl alcohol-glycerol-bright tripeptide amide analogue

Номер: CN0101519430A
Автор: YANG XINLING, KAI ZHENPENG, LING YUN, XIE YONG, HUANG JUAN, ZHANG JINRUI, CHEN FUHENG, XINLING YANG, ZHENPENG KAI, YUN LING, YONG XIE, JUAN HUANG, JINRUI ZHANG, FUHENG CHEN
Принадлежит:

The invention discloses a juvenile hormone synthesis inhibitor with novel structure, which is a phenylpropyl alcohol-glycerol-bright tripeptide amide analogue. The structure general formula of the compound provided by the invention is B: R-Leu-NH2, wherein the R stands for Phe-Gly-, Tyr-Gly-, PhCH2CH2CO-Gly-, PhCH=CHCO-Gly-, Ph(CH2)5CO-, Ph(CH2)4CO-, PhCH2NHCO(CH2)2CO-, PhCH2NHCO(CH2)3CO- or PhCH2NHCOCH2CO-. The compound with formula B simulates the chemical structure of a PHe-Gly-Leu-NH2 fragment of an A type AST and has simple structure and low synthesis cost. The compound has better inhibition activity for the juvenile hormone synthesis of black beetles. In the further application study, the compound obviously influences reproductive systems of female black beetles, inhibits the generation of black beetle eggs, conforms to the characteristic of an insect growth regulator and has better development and application prospects.

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Номер записи: 1
02-09-2009 дата публикации

Novel pentapeptide analogue and application thereof

Номер: CN0101519432A
Автор: YANG XINLING, KAI ZHENPENG, LING YUN, XIE YONG, HUANG JUAN, ZHANG LI, ZHANG JINRUI, CHEN FUHENG, XINLING YANG, ZHENPENG KAI, YUN LING, YONG XIE, JUAN HUANG, LI ZHANG, JINRUI ZHANG, FUHENG CHEN
Принадлежит:

The invention discloses a novel pentapeptide analogue and application thereof. The structure general formula of the compound provided by the invention is C: CR-Xaa-Phe-Gly-Leu-NH2, wherein the Xaa stands for the Gly, Asp, Asn, Ser or Ala; and the R stands for (substituted) benzoyl, (substituted) benzene acetyl, (substituted) hydrocinnamoyl, (substituted) butylbenzene, (substituted) benzene valeryl, (substituted) benzene hexanoyl, (substituted) benzenesulfonyl, 9-dimethoxycarbonyl, or benzyloxycarbonyl. Various organic acids with aromatic rings are introduced to replace Y/F in AST core pentapeptide (Y/FXFGLa) to prepare the pentapeptide analogue with simple structure and good inhibited juvenile hormone synthesis in-vitro activity, and the activity of partial compound with the formula C is superior to that of natural core pentapeptide. The further research indicates that partial compound with the formula C has better in-vivo activity, and the compound with the formula C conforms to the characteristic ...

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Номер записи: 2
02-09-2009 дата публикации

Insect allatostatin analogue modified by (substituted) phenylacrylic acid and application thereof in black beetle prevention

Номер: CN0101519433A
Автор: YANG XINLING, KAI ZHENPENG, LING YUN, XIE YONG, HUANG JUAN, ZHAO YICHEN, ZHANG JINRUI, CHEN FUHENG, XINLING YANG, ZHENPENG KAI, YUN LING, YONG XIE, JUAN HUANG, YICHEN ZHAO, JINRUI ZHANG, FUHENG CHEN
Принадлежит:

The invention discloses an insect allatostatin analogue modified by (substituted) phenylacrylic acid and application thereof in black beetle prevention. The structure general formula of the compound provided by the invention is A, wherein X stands for hydrogen, single or polysubstituted halogen, nitryl, methyl, ethide, methoxy or hydroxide radical. The compound with the formula A simulates the chemical structure of allatostatin core pentapeptide (Y/FXFGLa), has characteristics of simple structure and low synthesizing cost, and retains the in-vitro activity of natural allatostatin. The in-vitro activity of partial compounds is much higher than that of natural core pentapeptide, and some compounds have in-vivo activity which does not exist in the natural peptide. In the further application study, the compounds obviously influence reproductive systems of female black beetles, inhibit the generation of black beetle eggs, conform to the characteristic of an insect growth regulator and have better ...

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Номер записи: 3
02-09-2009 дата публикации

Peptide analogue juvenile hormone synthesis inhibitor containing phenylpropyl alcohol-glycerol-bright tripeptide fragment

Номер: CN0101519431A
Автор: YANG XINLING, KAI ZHENPENG, LING YUN, XIE YONG, HUANG JUAN, ZHANG JINRUI, CHEN FUHENG, XINLING YANG, ZHENPENG KAI, YUN LING, YONG XIE, JUAN HUANG, JINRUI ZHANG, FUHENG CHEN
Принадлежит:

The invention discloses a novel peptide analogue juvenile hormone synthesis inhibitor which has a structure general formula D: R-Phe-Gly-Leu-NH2, wherein the R stands for (substituted) benzoyl, (substituted) benzene acetyl, (substituted) hydrocinnamoyl, (substituted) butylbenzene, (substituted) benzene valeryl, (substituted) benzene hexanoyl, (substituted) benzene acryloyl, diacid, fatty acid, hydrophobic amino acid, or the like. For the compound with the formula D, a tripeptide fragment Phe-Gly-Leu-NH2 of AST is used as a primer, and an N-end modification method is adopted to obtain a novel peptide analogue compound containing Phe-Gly-Leu-NH2 tripeptide which has simple structure. The activity of most compounds with the formula D is superior to that of the tripeptide fragment Phe-Gly-Leu-NH2, and the activity of an individual compound is equal to or superior than the activity of core pentapeptide of the natural AST. In the further application study, the partial compounds with the formula ...

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Номер записи: 4