Composing prescription of novel safe JY immunoadjuvant system and uses thereof

The invention relates to a formula for a novel and safe JY immunity adjuvant system and the application, belonging to the field of pertinent, preventive and therapeutic vaccines. The formula which consists of polysaccharide with positive charges and cytokine (protein) with minus charges and stimulating immunity reaction, namely the JY adjuvant system, is used for mucosal immunity and system immunity of preventive vaccines and therapeutic vaccines to enhance the immunity effect of the vaccines. The JY adjuvant system with a reasonable formula has no obvious stimulation to mucosa tissues and the safety conforms to the requirements of medicines. The JY adjuvant system with the reasonable formula has generality and universality, can improve the effect of current vaccines and enhance immune response of new vaccines or availability of peptide or protein medicines in the JY adjuvant system.

Establishment of drug production system by non-virus bio-technology

A process for creating a non-viral disease preparing system by biotechnology is disclosed, which is aimed at creating the non-viral production specification and quality control standard of microbe products, including to use the equipment and technique for removing and/or deactivating virus and monitoring the viral pollution.

Convenient voucher payment fixing device

The invention relates to the technical field of voucher payment, in particular to a convenient voucher payment fixing device which comprises a placement plate, a limiting plate is mounted on the surface of the corresponding side of the placement plate, a bearing ring is mounted at the position, close to one end, of the surface of the corresponding side of the limiting plate, and a rotating rod is arranged in the bearing ring. Mounting plates are mounted at the positions, close to the two sides of the bottom end, of the outer surface of the rotating rod, movable screw rods are arranged in the two mounting plates, clamping tooth blocks are mounted at the bottom ends of the two screw rods through corresponding bearings correspondingly, and a through groove is formed in the position, close to the top end, of the interior of the rotating rod. Through the arrangement of parts such as a limiting plate, a rotating rod, a bearing ring, a screw rod, a clamping tooth block, a mounting rod, a gear, ...

Nasal cavity spraying inactivated influenza virus vaccine and its prepn process

Composing prescription of novel safe JY immunoadjuvant system and uses thereof

The invention relates to a formula for a novel and safe JY immunity adjuvant system and the application, belonging to the field of pertinent, preventive and therapeutic vaccines. The formula which consists of polysaccharide with positive charges and cytokine (protein) with minus charges and stimulating immunity reaction, namely the JY adjuvant system, is used for mucosal immunity and system immunity of preventive vaccines and therapeutic vaccines to enhance the immunity effect of the vaccines. The JY adjuvant system with a reasonable formula has no obvious stimulation to mucosa tissues and the safety conforms to the requirements of medicines. The JY adjuvant system with the reasonable formula has generality and universality, can improve the effect of current vaccines and enhance immune response of new vaccines or availability of peptide or protein medicines in the JY adjuvant system.

Nucleic acid, kit and detection method for multiple real-time fluorescent quantitative RT-PCR (Reverse Transcription-Polymerase Chain Reaction) detection of group A rotavirus genotyping

The invention belongs to the technical field of microorganisms, and discloses nucleic acid, a kit and a detection method for multiple real-time fluorescent quantitative RT-PCR (Reverse Transcription-Polymerase Chain Reaction) detection of group A rotavirus genotypes. The detected genotypes comprise G1, G2, G3, G4, G8, G9, P [4], P [6] and P [8], grouping detection is carried out, at least two genotypes are detected in each group, preferably three groups are detected, G1, G9 and P [6] are a group A, G2, G4 and P [4] are a group B, and G3, G8 and P [8] are a group C. According to the method, the nine genotypes of the group A rotavirus can be rapidly and efficiently detected, rare samples can be effectively saved, meanwhile, reagents are saved, high sensitivity and specificity are achieved, result interpretation is simple, application is convenient, and reference is provided for specific detection of the group A rotavirus genotypes and prevention and control of the group A rotavirus.

Application of chimeric antigen receptor macrophages in solid tumor immunotherapy

The invention relates to application of chimeric antigen receptor macrophages in solid tumor immunotherapy. In particular to a VEGFR2 (vascular endothelial growth factor receptor 2) targeting chimeric antigen receptor, a coding nucleic acid and an expression vector thereof, an immune response cell (such as macrophage) for expressing the chimeric antigen receptor, and application of the chimeric antigen receptor in treatment of breast cancer.

AUTOMATIC SAFE BOLT FOR DOORS AND WINDOWS

The present invention relates to a safe and automatic door and window bolt. It is made up by using a punched casing made of thin iron sheet and by assembling bolt and spring together. It is easy to install without damage to the paint film of door and window, and can save labor and easily and automatically open and close the door and window. Besides, it can protect door and window glass from damaging, and its cost is low, appearance is good-looking, and durable.