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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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19-01-2018 дата публикации

벼메뚜기에서 유래한 항균 펩타이드 옥시야신-4 및 그의 조성물

Номер: KR0101820086B1

Автор: 황재삼, 윤은영, 안미영, 김미애, 김성현, 남성희, 이준하, 김인우

Принадлежит: 대한민국

... 본 발명은 벼메뚜기로부터 분리한 신규한 옥시야신-4 펩타이드 및 그의 조성물에 관한 것이다. 본 발명에서 화학적으로 합성된 펩타이드(Oxyasin-4)는 그람 양성균, 그람 음성균 또는 진균류에 대한 강한 항균 작용을 나타내면서도 세포 독성이 거의 없기 때문에 항균제, 항진균제, 항생제, 식품 방부제, 화장품 보존제, 의약품 보존제 등으로 유용하게 사용할 수 있다.

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Номер записи: 1

03-02-2017 дата публикации

장수풍뎅이 유충 또는 이의 분획물을 유효성분으로 함유하는 간보호 및 항암용 조성물

Номер: KR0101702046B1

Автор: 윤은영, 황재삼, 강병헌, 이지은, 조다은, 이안중, 박혜경

Принадлежит: 대한민국(농촌진흥청장), 울산과학기술원

... 본 발명은 장수풍뎅이 유충 또는 이의 분획물을 유효성분으로 포함하는 간보호 효과와 항암 활성 활성을 나타내는 조성물에 관한 것이다. DEN으로 처리된 쥐에서는 혈중 알칼라인 포스파타제(alkaline phosphatase ,ALP) 농도, TUNEL positive 간세포의 숫자, 간 손상으로 인해 형성되는 duct의 개수, 간세포에서의 지방축적, Masson's trichrome 염색에서 콜라겐 염색 정도 등, 급성 혹은 만성 간 손상과 관련된 지표들이 모두 증가되지만, 장수풍뎅이 유충 동결건조 분말을 함께 경구투여하게 되면, 이와 같은 간 손상의 지표들이 통계적으로 유의미한 수준으로 감소하게 되는 것을 확인할 수 있었다. 장수풍뎅이 유충 분획물들을 여러 종류의 암세포주에 처리하였을 때, 에틸아세테이트 분획물이 암세포들에 대해서 아포토시스와 세포괴사와 같은 세포죽음을 유도하는 활성이 있음을 확인할 수 있었다. 더불어 에틸아세테이트 분획물은 암세포의 대사를 교란할 수 있었고, 오토파지를 유도할 수 있는 활성을 가지고 있었다.

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Номер записи: 2

03-02-2017 дата публикации

장수풍뎅이 유충 또는 이의 분획물을 유효성분으로 함유하는 간보호 및 항암용 조성물

Номер: KR0101702053B1

Автор: 윤은영, 황재삼, 강병헌, 이지은, 조다은, 이안중, 박혜경

Принадлежит: 대한민국(농촌진흥청장), 울산과학기술원

... 본 발명은 장수풍뎅이 유충 또는 이의 분획물을 유효성분으로 포함하는 간보호 효과와 항암 활성 활성을 나타내는 조성물에 관한 것이다. DEN으로 처리된 쥐에서는 혈중 알칼라인 포스파타제(alkaline phosphatase ,ALP) 농도, TUNEL positive 간세포의 숫자, 간 손상으로 인해 형성되는 duct의 개수, 간세포에서의 지방축적, Masson's trichrome 염색에서 콜라겐 염색 정도 등, 급성 혹은 만성 간 손상과 관련된 지표들이 모두 증가되지만, 장수풍뎅이 유충 동결건조 분말을 함께 경구투여하게 되면, 이와 같은 간 손상의 지표들이 통계적으로 유의미한 수준으로 감소하게 되는 것을 확인할 수 있었다. 장수풍뎅이 유충 분획물들을 여러 종류의 암세포주에 처리하였을 때, 에틸아세테이트 분획물이 암세포들에 대해서 아포토시스와 세포괴사와 같은 세포죽음을 유도하는 활성이 있음을 확인할 수 있었다. 더불어 에틸아세테이트 분획물은 암세포의 대사를 교란할 수 있었고, 오토파지를 유도할 수 있는 활성을 가지고 있었다.

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Номер записи: 3

19-04-2016 дата публикации

ANTICANCER COMPOSITION CONTAINING PROTAETIA BREVITARSIS SEULENSIS LARVA OR FRACTION THEREOF AS ACTIVE INGREDIENT

Номер: KR1020160042283A

Автор: YUN, EUN YOUNG, HWANG, JAE SAM, GOO, TAE WON, KANG, BYOUNG HEON, LEE, JI EUN, JO, DA EUN, LEE, AN JUNG

Принадлежит:

The present invention relates to an anticancer composition containing Protaetia brevitarsis seulensis larva or a fraction thereof as an active ingredient. In addition, the present invention further relates to a method for producing a fraction derived from Protaetia brevitarsis seulensis larva having anticancer effects, which comprises the followings: a first step of sterilizing the Protaetia brevitarsis seulensis larva under a high pressure, freeze-drying the same, and pulverizing the same; a second step of mixing the pulverized Protaetia brevitarsis seulensis larva powder obtained from the first step along with ethanol so as to produce a Protaetia brevitarsis seulensis ethanol extract; and a third step of obtaining the fraction by sequentially fractionizing the Protaetia brevitarsis seulensis ethanol extract produced from the second step by means of hexane, ethyl acetate, butanol, and water. According to the present invention, by containing the Protaetia brevitarsis seulensis larva or ...

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Номер записи: 4

04-07-2017 дата публикации

CYLINDER FOR SWASH PLATE TYPE COMPRESSOR

Номер: KR1020170076434A

Автор: YOON, EUN YOUNG, KWAK, JUNG MIN, KIM, KYUNG TAE, YIM, DONG WON, KIM, SANG HYUK

Принадлежит:

The present invention is to provide a cylinder for a swash plate type compressor, capable of lowering the temperature of a cylinder bore adjacent to a discharge muffler cavity through which a high-temperature and high-pressure refrigerant flows. According to the present invention, the cylinder for a swash plate type compressor coupled to a housing having suction and discharge chambers, and having an end defining a portion of a swash plate chamber, comprises: a cylinder body; a plurality of cylinder bores including first and second cylinder bores each formed to penetrate the cylinder body in lengthwise direction thereof, and in which a piston moves reciprocally; a discharge muffler cavity formed in the cylinder body to surround a portion of the first cylinder bore, and configured to guide a high-temperature and high-pressure refrigerant of the discharge chamber to a discharge port; and a cooling hole formed between the first and second cylinder bores to penetrate the cylinder body in lengthwise ...

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Номер записи: 5

21-06-2018 дата публикации

호박벌 여왕벌 글라이코자미노글라이칸의 지방축적억제 용도

Номер: KR0101869792B1

Автор: 안미영, 황재삼, 윤형주, 윤은영, 김하정, 김반지

Принадлежит: 대한민국

... 호박벌여왕벌 유래 글라이코자미노글라이칸은 고지방 식이 시 체내 복부지방 축적을 억제하며 콜레스테롤 함량을 감소시키며 혈청내 유리지방산을 감소시킨다. 혈장 내 APTT(activated partial thromboplastine time, 활성된 부분 트롬보프라스틴 시간)을 연장하여 혈액응고를 방지하며 혈관내피에 존재하는 접착단백질관련 라미닌을 억제한다. 또한 혈중 글로블린의 단백손상을 억제하고 간세포의 과산화지질 축적(MDA 양)을 억제한다. 또한 세포수준에서 볼 때, 혈관내피세포에서 NO(산화질소)를 발생시켜 혈관이완시킨다. 더불어 랫트 한 달 투여 후 고지방식이에 의한 혈압상승을 방지함을 확인할 수 있었다. 호박벌여왕벌 유래 글라이코자미노글라이칸은 지질축적 억제, 세포막접착성단백질 부착억제, 혈압강하, 혈전예방의 용도 조성물을 제공한다.

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Номер записи: 6

11-12-2018 дата публикации

신규한 헤테로고리 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 암의 예방 또는 치료용 약학적 조성물

Номер: KR0101927375B1

Автор: 박성준, 허정녕, 김광록, 김성수, 임환정, 이혁, 장성연, 김범태, 윤은영, 임병호

Принадлежит: 한국화학연구원

... 본 발명은 신규한 헤테로고리 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 NAE(NEDD8-Activating Enzyme) 또는 SAE(Sumo Activating Enzyme) 관련 질환의 예방 또는 치료용 약학적 조성물에 관한 것으로, 본 발명에 따른 헤테로고리 화합물은 NAE(NEDD8-Activating Enzyme) 또는 SAE(Sumo Activating Enzyme)를 나노몰 단위의 농도로 우수하게 저해할 수 있어, 이를 유효성분으로 함유하는 NAE(NEDD8-Activating Enzyme) 또는 SAE(Sumo Activating Enzyme) 관련 질환 예를 들어, 암의 예방 또는 치료용 약학적 조성물로 유용하게 사용될 수 있다.

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Номер записи: 7

18-01-2017 дата публикации

스콜로펜드라신-1 펩타이드를 유효성분으로 포함하는 아토피성 피부염 예방 및 치료용 조성물

Номер: KR0101697179B1

Автор: 황재삼, 윤은영, 남성희, 안미영, 김미애, 이준하, 김인우, 김상희, 강태진, 이금선, 이기만

Принадлежит: 대한민국(농촌진흥청장), 삼육대학교산학협력단

... 본 발명은 스콜로펜드라신-1 펩타이드를 유효성분으로 포함하는 아토피성 피부염 예방 및 치료용 조성물에 관한 것이다. 본 발명은 서열번호 1로 표현되며, 왕지네(Scolopendrasubspinipes)로부터 분리된 스콜로펜드라신-1 펩타이드를 유효성분으로 포함하는 아토피성 피부염 예방 및 치료용 약학적 조성물이 제공된다. 본 발명에 의해, 아토피 피부염을 완화시킬 뿐만 아니라, 면역글로불린E의 수치를 저하시키고 비만세포의 활성화를 통해 분비되는 염증매개물질인 히스타민과 프로스타글란딘D2의 분비를 억제하는 아토피성 피부염 예방 및 치료용 조성물이 제공된다.

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Номер записи: 8

23-06-2017 дата публикации

SWASH PLATE TYPE COMPRESSOR WITH OIL SEPARATOR

Номер: KR1020170071065A

Автор: KWAK, JUNG MIN, SEOK, JAE BIN, KIM, KYUNG TAE, YUN, EUN YOUNG, YIM, DONG WON

Принадлежит:

A swash plate type compressor comprises: a housing having a cylinder block therein; a driving shaft mounted onto the housing to be rotated; a swash plate coupled to the driving shaft to be rotated with the driving shaft and arranged in the housing; a plurality of pistons enabling suction, extrusion, and discharge of a refrigerant while reciprocating to correspond to rotation of the swash plate; a front head coupled to a front side of the housing; a rear head coupled to a rear side of the housing and formed with a discharge port; an oil separator arranged in the discharge port of the rear head so as to separate oil mixed in the refrigerant; an oil chamber for storing the oil separated by the oil separator; and an oil introduction path for introducing the oil stored in the oil chamber into the housing, wherein the oil introduction path connects the oil chamber with an inner space of the housing by passing through the outside of the housing. COPYRIGHT KIPO 2017 ...

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Номер записи: 9

04-11-2022 дата публикации

지방 함량 증대를 위한 갈색거저리용 사료의 제조방법

Номер: KR102462551B1

Автор: 윤은영, 황두선, 이상훈, 김인덕, 이진안, 이혜진, 안재권

Принадлежит: 그린테코 주식회사, 세종대학교 산학협력단

... 본 발명은 발효된 밀기울과 가공된 음식물쓰레기를 소정 크기로 성형시켜 증체량, 지방함량 및 사육 효율을 높인 갈색거저리용 사료 및 이의 제조방법에 관한 것이다.

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Номер записи: 10

13-12-2012 дата публикации

SWING LINK FOR A SCROLL COMPRESSOR AND METHOD FOR TREATING THE SURFACE OF SAME

Номер: WO2012169763A3

Автор: YOON, Eun Young, CHOI, Yong Wan, JOO, Sang Hyun, BAE, Jae Hyun, SHIN, Jin Young, LEE, Jae Wook

Принадлежит:

The present invention relates to a swing link for a scroll compressor, and more particularly, to a swing link for a scroll compressor having improved abrasion resistance, corrosion resistance, and durability, and to a method for treating the surface of the swing link. The method for treating the surface of the swing link for the scroll compressor, which involves treating the outer surface of the swing link for the scroll compressor having a cylindrical unit and a balance weight, comprises: a stress-removing step of removing internal stresses of the swing link; a normalizing step of smoothing the internal organization of the swing link; and a low-temperature nitrocarburizing step of leaving the swing link in a gaseous nitrocarburizing atmosphere in a nitrocarburizing furnace for a predetermined period of time and then cooling the swing link in an inactive nitrification furnace.

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Номер записи: 11

12-11-2018 дата публикации

유충을 이용한 기능성 메주 및 이의 제조방법

Номер: KR0101917755B1

Автор: 윤은영, 이우석

Принадлежит: 세종대학교산학협력단, (주) 유니버샬 팜스밀

... 본 발명은 유충을 이용한 기능성 메주 및 이의 제조방법에 관한 것으로, 더욱 상세하게는 식물성 단백질인 대두를 사용하지 않고 동물성 단백질인 흰점박이꽃무지, 갈색거저리 및 장수풍뎅이의 유충만을 이용하여 황국균에 의해 발효된 기능성 메주 및 이의 제조방법으로, 미래 식량부족 문제를 해결하기 위한 대체식량자원으로의 가치가 있으며, 식용곤충을 가공한 식품을 개발함으로써 다양한 먹거리 및 부가가치를 제공하고 농가소득에 기여하는 효과가 있는 유충을 이용한 기능성 메주 및 이의 제조방법에 관한 것이다.

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Номер записи: 12

16-12-2016 дата публикации

장수풍뎅이 추출물을 유효성분으로 포함하는 류마티스 관절염 예방 또는 치료용 조성물

Номер: KR0101686420B1

Автор: 윤은영, 황재삼, 구태원, 김미애, 윤영일

Принадлежит: 대한민국

... 본 발명은 장수풍뎅이 추출물을 유효성분으로 포함하는 류마티스 관절염 예방 또는 치료용 조성물에 관한 것이다. 본 발명인 항류마티스효과를 갖는 장수풍뎅이 추출물의 제조방법은, 장수풍뎅이(Allomyrina dichotoma)를 2~3일 동안 굶겨 배변을 시킨다음. 멸균한 후, 동결건조한 다음 분쇄시키는 제1단계, 상기 제1단계에서 분쇄된 장수풍뎅이와 에탄올을 혼합하여 장수풍뎅이 혼합액을 제조하는 제2단계, 상기 제2단계에서 제조된 장수풍뎅이 혼합액을 초음파 분쇄기로 미세화시키는 제3단계 및, 상기 제3단계에서 미세화된 장수풍뎅이 혼합액을 원심분리 시킨 후, 상층액을 회수하고 여과시키는 제4단계를 포함하여, 파골세포 분화억제를 통해 항류마티스효과를 갖는 것이 특징이다. 본 발명에 의해, 파골세포 분화억제를 통해 항류마티스 효과를 갖는 장수풍뎅이 추출물을 유효성분으로 포함하는 류마티스 관절염 예방 또는 치료용 조성물이 제공된다.

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Номер записи: 13

04-01-2017 дата публикации

COMPOSITION FOR LIVER PROTECTION OR ANTICANCER COMPRISING ALLOMYRINA DICHOTOMA LARVAE OR FRACTION THEREOF AS ACTIVE INGREDIENT

Номер: KR1020170000834A

Автор: YUN, EUN YOUNG, HWANG, JAE SAM, KANG, BYOUNG HEON, LEE, JI EUN, JO, DA EUN, LEE, AN JUNG, PARK, HYE KYUNG

Принадлежит:

The present invention relates to a composition having an effect of liver protection and anticancer activity, which comprises an Allomyrina dichotoma larvae or a fraction thereof as an active ingredient. In mice treated with DEN, all of the indices related with acute or chronic liver damage, including the concentration of alkaline phosphatase (ALP) in blood, the number of TUNEL positive hepatocytes, the number of ducts formed by liver damage, fat accumulation in hepatocytes and the degree of collagen staining in Masson′s trichrome staining, are increased. However, it is shown that when freeze dried powder of Allomyrina dichotoma larvae is administered orally, such liver damage indices are reduced to a statically significant level. When various types of cancer cell lines are treated with the fractions of Allomyrina dichotoma larvae, it is shown that an ethyl acetate fraction has an activity of inducing cell destruction, such as apoptosis and cell necrosis, to cancer cells. In addition, the ...

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Номер записи: 14

04-10-2018 дата публикации

COMPOSITION COMPRISING COMPOUND ISOLATED FROM TENEBRIO MOLITOR LARVA FOR ANTITHROMBOSIS

Номер: KR1020180108094A

Автор: KIM, MI AE, HWANG, JAE SAM, YUN, EUN YOUNG, KIM, SEONG HYUN, BAE, JONG SUP, NA, MIN KYUN, PARK, IN WHA

Принадлежит:

The present invention relates to a composition comprising at least one kind of compounds selected from a group consisting of cyclo (L-proline-L-tyrosine) (compound 1), N-acetyl tyramine (compound 2) and hydroxcitrosol (compound 3) for antithrombosis, antiplatelet or anticoagulation. The compound inhibits a blood coagulation pathway through the inhibition of FXa in HUVEC, inhibits platelet aggregation in vitro and in vivo, and thus can be usefully used as a pharmaceutical composition or health functional food for treatment or prevention of vascular diseases associated with the blood coagulation. COPYRIGHT KIPO 2018 ...

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Номер записи: 15

18-04-2016 дата публикации

COMPOSITION FOR PREVENTING OR TREATING OBESITY COMPRISING TENEBRIO MOLITOR LARVA EXTRACT OR TENEBRIO MOLITOR LARVA SUSPENSION AS ACTIVE INGREDIENT

Номер: KR1020160041138A

Автор: YUN, EUN YOUNG, HWANG, JAE SAM, GOO, TAE WON, KIM, MI AE, CHUNG, MI YEON

Принадлежит:

The present invention relates to a composition for preventing or treating obesity comprising Tenebrio molitor larva extract or Tenebrio molitor larva suspension. The method for preparing Tenebrio molitor larva extract having an anti-obesity effect includes a first step of pulverizing freeze-dried Tenebrio molitor larva; a second step of mixing the powder of Tenebrio molitor larva with ethanol to provide a mixed liquid of Tenebrio molitor; a third step of refining the mixed liquid of Tenebrio molitor with an ultrasonic pulverizer; and a fourth step of subjecting the refined mixed liquid of Tenebrio molitor to centrifugal separation and recovering the supernatant, followed by filtering, to obtain Tenebrio molitor larva extract having an anti-obesity effect. The anti-obesity composition comprising Tenebrio molitor larva extract or Tenebrio molitor larva suspension as an active ingredient shows no side effect, has excellent safety and an anti-obesity effect, and thus can be used as an agent ...

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Номер записи: 16

11-10-2012 дата публикации

OIL SEPARATION STRUCTURE FOR A SCROLL TYPE COMPRESSOR

Номер: WO2012138101A2

Автор: YUN, Eun Young, CHOI, Yong Wan, JOO, Sang Hyun, BAE, Jae Hyun, SHIN, Jin Young, LEE, Jae Wook

Принадлежит:

The present invention relates to an oil separation structure for a scroll type compressor. In the oil separation structure, a receiving part is formed in a back surface of a fixed scroll including a circular end plate and a spiral element protruding from a front surface of the circular end plate, and an oil separator for separating oil from compressed refrigerant within the receiving part. Also, a rear housing is installed on a back surface of the fixed scroll, an opening is formed in one end of the receiving part, and a closed part is formed on the other end of the receiving part. Also, a refrigerant introduction hole is formed in one side of a sidewall of the receiving part.

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Номер записи: 17

25-10-2017 дата публикации

COMPOSITION COMPRISING TELEOGRYLLUS EMMA EXTRACT FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASE

Номер: KR101790018B1

Автор: YUN, EUN YOUNG, HWANG, JAE SAM, KIM, MI AE, PARK, KWAN HO, YOON, YOUNG IL

Принадлежит: REPUBLIC OF KOREA(MANAGEMENT : RURAL DEVELOPMENT ADMINISTRATION)

The present invention relates to a composition comprising a Teleogryllus emma extract for preventing or treating inflammatory bowel disease, wherein the Teleogryllus emma extract increases the survival rate of a wild-type Drosophilidae fed with an inflammatory bowel disease-inducing material, or Drosophilidae having suppressed immunoreactivity, and has an excellent effect of suppressing the expression of an inflammatory bowel disease-related gene. Therefore, a pharmaceutical composition or health functional food comprising the Teleogryllus emma extract may be useful as a composition for treating inflammatory bowel disease, such as Crohn′s disease or ulcerative colitis, which is difficult to treat with general anti-inflammatory or anti-inflammatory drugs, or health functional food for preventing and improving the diseases. COPYRIGHT KIPO 2017 ...

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Номер записи: 18

16-11-2016 дата публикации

GASKET FOR COMPRESSOR

Номер: KR1020160131255A

Автор: KWAK, JUNG MIN, BAE, JAE HYUN, NAM, JEOUNG HAG, KIM, KYUNG TAE, YOON, EUN YOUNG, YIM, DONG WON

Принадлежит:

The present invention provides a gasket for a compressor, capable of enhancing durability of the gasket. To this end, the gasket for a compressor of the present invention, in which a discharge valve, a valve plate, and a suction valve are interposed between a housing having a discharge chamber and a suction chamber and a cylinder block having a plurality of cylinder bores, comprises: a gasket body having a disc shape including a central surface and an edge surface on the same plane; a driving shaft insertion hole formed at the central surface of the gasket body and allowing a driving shaft to be inserted therein; a discharge refrigerant flow channel hole formed between the central surface and the edge surface of the gasket body, having a shape of covering the driving shaft insertion hole, and communicating with the discharge chamber of the housing; and a plurality of suction refrigerant flow channel holes having a circular shape, formed at intervals along a circumference of the edge surface ...

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Номер записи: 19

10-07-2017 дата публикации

MAGNETOTACTIC SELF-ASSEMBLED MOLECULAR ARCHITECTURES AND PREPARATION METHOD THEREOF

Номер: KR1020170078936A

Автор: LEE, HEE SEUNG, KWON, SUN BUM, YOO, SUNG HYUN, GONG, JIN TAEK, YOON, EUN YOUNG

Принадлежит:

The present invention relates to magnetotactic self-assembled molecular architectures and a preparation method thereof. Foldectures, which are magnetotactic self-assembled molecular architectures, are assembled by themselves by external magnetic fields. The arrangement direction is changed according to directions of the magnetic fields. The foldectures response and are arranged, thereby showing magnetotactic properties enabling a real-time rotary motion in an aqueous solution. Accordingly, the foldectures can be used in various application research fields such as a peptide magnetic compass, a stimuli-responsive molecular machine, control of movements of organic nanomaterials, etc. COPYRIGHT KIPO 2017 (AA) Foldectures suspension (BB) Horizontal plane magnetic field (CC) Vertical plane magnetic field (D1,D2) Evaporation ...

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Номер записи: 20

27-04-2017 дата публикации

항염증 활성을 갖는 풀색꽃무지 추출물 및 이를 함유하는 조성물

Номер: KR0101730065B1

Автор: 윤은영, 황재삼, 김미애, 이영보, 윤영일

Принадлежит: 대한민국

... 본 발명은 항염증 활성을 갖는 풀색꽃무지(Gametis jucunda) 추출물 및 이를 함유하는 조성물에 관한 것이다. 본 발명의 항염증 활성을 갖는 풀색꽃무지 추출물은 풀색꽃무지(Gametis jucunda)를 용매로 추출하여 수득되는 것을 특징으로, 또 다른 관점에서는 상기 풀색꽃무지 추출물을 유효성분으로 포함하는 염증성질환 예방 및 치료용 약학조성물 또는 염증성 질환 예방 및 개선용 식품조성물을 제공한다. 본 발명에 따른 항염증활성을 갖는 풀색꽃무지 추출물 및 이를 포함하는 조성물은 곤충유래 천연자원으로서 세포독성이 없어 안전성이 우수할 뿐만 아니라 염증 관련 인자의 발현을 억제하여 항염증 효과을 가짐으로써 다양한 질병의 원인이 되는 염증의 예방 및 치료제로서 사용이 가능하다.

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Номер записи: 21

21-09-2017 дата публикации

METHOD FOR PRODUCING TIN THIN FILM FOR SEPARATION PLATES IN POLYMER ELECTROLYTE MEMBRANE FUEL CELLS (PEMFCs) USING PLASMA ENHANCED ATOMIC LAYER DEPOSITION (PEALD)

Номер: KR1020170106570A

Автор: KWON, SE HUN, YUN, EUN YOUNG, KIM, KWANG HO

Принадлежит:

Provided is a method for producing a fuel cell separation plate for forming TiN thin films on a metal base material such as stainless using a plasma enhanced atomic layer deposition (PEALD) method. More specifically, provided is a method for producing a polymeric electrolyte fuel cell separation plate. To this end, the polymeric electrolyte fuel cell separation plate includes a TiN coating layer formed on stainless steel. The TiN coating layer is formed at a low processing temperature of 100-300°C using reaction gas and an organometallic compound precursor via an atomic layer deposition method or a PEALD method, or can be formed at a high processing temperature of 300-500°C using reaction gas and a metal halogen compound precursor. COPYRIGHT KIPO 2017 ...

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Номер записи: 22

01-10-2018 дата публикации

FUNCTIONAL SALTED SEAFOOD USING LARVA OF EDIBLE INSECTS, PRODUCTION METHOD THEREOF, AND FUNCTIONAL HEALTH FOOD CONTAINING SAME

Номер: KR1020180106905A

Автор: YUN EUN YOUNG

Принадлежит:

The present invention relates to a functional salted seafood using larva of edible insects, a production method thereof, and a functional health food containing the same. More specifically, the present invention relates to functional salted seafood using larva of edible insects, which is valuable as an alternative food resource to solve future food shortage problems, provides various foods and added value by developing edible insect-processed foods, contributes to farm income, and prevents or improves various diseases, conditions, and the like which can be prevented or improved by antioxidant activities. The present invention further relates to a production method thereof, and a functional health food containing the same. COPYRIGHT KIPO 2018 ...

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Номер записи: 23

21-09-2022 дата публикации

사진 데이터를 이용한 기억력 증강 장치, 사진 데이터를 이용한 기억력 증강 방법, 및 컴퓨터 판독 가능한 기록 매체

Номер: KR20220128576A

Автор: 윤은영, 윤일한

Принадлежит:

... 본 발명의 최소한 하나의 실시예에 따른 사진 데이터를 이용한 기억력 증강 장치는, 모바일 기기의 메모리, 상기 모바일 기기의 메모리의 데이터를 백업한 외부 메모리, 또는 온라인 저장소로부터 사진 데이터를 취득하기 위한 데이터 취득부, 상기 데이터 취득부가 취득한 상기 사진 데이터의 사진과 상기 사진에 관련된 기본 정보를 연동하여 저장하기 위한 데이터 저장부, 상기 데이터 저장부에 저장된 데이터의 적어도 일부를 시각 및 청각의 적어도 하나를 통해 사용자에게 제시하는 데이터 제시부, 상기 사용자가 상기 데이터 제시부가 제시한 상기 데이터를 확인하면, 확인한 직후 또는 소정의 시간 후에 상기 사용자가 확인한 상기 데이터를 기억하고 있는지 테스트하는 테스트부, 상기 테스트부를 통한 테스트 결과에 따라 상기 사용자의 기억 점수를 산출하는 기억점수 산출부, 및 상기 기억점수 산출부가 산출한 상기 기억 점수를 토대로 상기 사용자에게 적합한 테스트 방법을 제안하는 테스트방법 제안부를 구비한다.

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Номер записи: 24

30-06-2016 дата публикации

TRANSGENIC SILKWORMS PRODUCING BLUE FLUORESCENT COCOONS

Номер: KR0101634272B1

Автор: 구태원, 윤은영, 최광호, 김성렬, 박승원, 김성완

Принадлежит: 대한민국

... 본 발명은 청색 형광 실크를 생산하는 형질전환 누에에 관한 것이다. 본 발명의 청색 형광 실크를 생산하는 형질전환 누에는, 표지 유전자 조절 프로모터, 표지 유전자, 누에 유래의 피브로인(Fibroin) 프로모터 및 해파리(Aequorea macrodactyla) 유래 청색 형광 유전자인 EBFPco가 작동가능하게 연결된 유전자 컨스트럭트를 포함하는 재조합 발현벡터를 제작하여 상기 재조합 발현벡터로 누에를 형질전환시킴으로써 청색 형광 실크를 생산하는 것이 특징이다. 본 발명에 의해, 자연광에서도 진한 천연의 청색을 나타내어 별도의 염색이 필요 없어 친환경적이고 경제적이며 특정 파장의 빛을 쏘이면 어둠 속에서 영롱한 청색을 나타내어 일반 실크에 비해 훨씬 고부가가치의 고급 패션의류나 벽지 등의 소재로 유용하게 사용될 수 있는 청색 형광 실크가 제공된다.

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Номер записи: 25

12-05-2017 дата публикации

INSECT MEAT COMPOSITION USING TENEBRIO MOLITOR AND MANUFACTURING METHOD THEREOF

Номер: KR101734067B1

Автор: YUN, EUN YOUNG, HWANG, JAE SAM, KIM, MI AE, KIM, HYUNG MI, KIM, JUNG NAM, YOO, HYUN JI, LEE, NA RAE, OH, GEUM RYE, JEONG, MI YOUNG

Принадлежит: REPUBLIC OF KOREA(MANAGEMENT : RURAL DEVELOPMENT ADMINISTRATION), INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY

The present invention relates to an insect meat composition using Tenebrio molitor and a manufacturing method thereof. The insect meat composition of the present invention contains 18-30 wt% of Tenebrio molitor powder based on the total weight of the composition. The present invention provides an insect meat composition using Tenebrio molitor and a manufacturing method thereof, wherein, by using Tenebrio molitor as alternative protein food for beef according to the present invention, a balanced protein source not containing cholesterol, which is a problem in regular animal meat, is provided, and an effective supply of nutrients for patients who eat a small amount of food is possible at the same time. The Tenebrio molitor can offer similar mouthfeel to animal meat. COPYRIGHT KIPO 2017 (AA) Example 1 (BB) Comparative example 1 (CC) Comparative example 2 ...

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Номер записи: 26

28-12-2017 дата публикации

DASIK USING TENEBRIO MOLITOR, AND METHOD OF MAKING SAME

Номер: KR1020170142350A

Автор: YUN, EUN YOUNG, HWANG, JAE SAM, KIM, MI AE, KIM, HYUNG MI, KIM, SEONG HYEON, SHON, JIN YOUNG

Принадлежит:

The present invention relates to a Dasik(bite-size hangwa) using Tenebrio molitor, and a method of making the same, wherein the Dasik comprises 1-30 wt% of Tenebrio molitor powder with respect to the total wt% of the composition. Further, the present invention has a high nutritional value due to having high protein and mineral contents, has a desirable chewing sensation, and can be ingested conveniently through various routes outside meal times. Additionally, the present invention has desirable taste and aroma while containing beneficial effects of Tenebrio molitor, and thus may be provided as a nutritional food supplement suitable for patients or growing children who need an intake of protein of good quality. COPYRIGHT KIPO 2018 ...

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Номер записи: 27

04-02-2016 дата публикации

NEW SCOLOPENDRASIN-5 PEPTIDE ISOLATED FROM SCOLOPENDRA SUBSPINIPES AND COMPOSITION OF SAME

Номер: KR1020160013323A

Автор: HWANG, JAE SAM, YUN, EUN YOUNG, NAM, SUNG HEE, AHN, MI YOUNG, KIM, MI AE, LEE, JOON HA, KIM, IN WOO, KIM, SAGN HEE

Принадлежит:

The present invention relates to a new scolopendrasin-5 peptide isolated from Scolopendra subspinipes and a composition of the same. In the present invention, provided is a peptide which is synthesized from amino acid deducted from a gene of a peptide isolated from Scolopendra subspinipes, and is expressed by SEQ ID NO: 1. According to the present invention, provided are a new scolopendrasin-5 peptide isolated from Scolopendra subspinipes and a composition of the same which can provide antibiotics, food preservatives, cosmetic preservatives, medicines, etc., which are safe to the human body while expressing antifungal activity without cytotoxicity. COPYRIGHT KIPO 2016 (AA) Unit(μg, ml) ...

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Номер записи: 28

12-02-2016 дата публикации

NOVEL CECROPIN-LIKE ANTIFUNGAL PEPTIDE AND SYNTHETIC COMPOSITION THEREOF

Номер: KR1020160014805A

Автор: HWANG, JAE SAM, YUN, EUN YOUNG, NAM, SUNG HEE, AHN, MI YOUNG, KIM, MI AE, LEE, JOON HA, KIM, IN WOO, KIM, SAGN HEE, LEE, DONG GUN, LEE, WON YOUNG, CHOI, HYE MIN

Принадлежит:

The present invention relates to a novel cecropin-like antifungal peptide and a composition thereof. The antifungal peptide of the present invention is represented by SEQ ID NO: 2, and is synthesized from an amino acid deducted from a gene of a peptide represented by SEQ ID NO: 1. According to the present invention, provided are a novel cecropin-like antifungal peptide separated from scolopendra subspinipes, which has remarkable antifungal activity without cytotoxicity, and a composition thereof. Therefore, according to the present invention, an antibiotic as an antifungal medicine safe to human body, a food preservative, a cosmetic preserving agent, a medicine, etc., can be provided. COPYRIGHT KIPO 2016 ...

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Номер записи: 29

03-01-2017 дата публикации

HEPATOPROTECTIVE ANTICANCER COMPOSITION COMPRISING ALLOMYRINA DICHOTOMA LARVA OR FRACTION THEREOF AS EFFECTIVE COMPONENT

Номер: KR1020170000818A

Автор: YUN, EUN YOUNG, HWANG, JAE SAM, KANG, BYOUNG HEON, LEE, JI EUN, JO, DA EUN, LEE, AN JUNG, PARK, HYE KYUNG

Принадлежит:

The present invention relates to a composition which comprises Allomyrina dichotoma larva or a fraction thereof as an effective component and shows liver protection effects and anti-cancer activities. In DEN-treated mice, signs of acute or chronic liver damage such as alkaline phosphatase (ALP) level in the blood serums, the number of TUNEL-positive hepatocytes, the number of ducts formed by liver damage, adiposity of hepatocytes, and the degree of collagen deposition of the Masson′s trichrome stain all increased. However, the signs of liver damage significantly decreased when freeze-dried powder of Allomyrina dichotoma larva was orally administered. When various cancel cell lines were treated with fractions of Allomyrina dichotoma larva, an ethylacetate fraction thereof showed cytotoxicity to cancer cells through the induction of apoptosis and necrosis. Further, the ethylacetate fraction was able to perturb the metabolism of the cancer cell, and had the cytotoxicity to trigger autophagy ...

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Номер записи: 30

27-09-2018 дата публикации

FUNCTIONAL FERMENTED SOYBEAN LUMP USING LARVAE AND METHOD FOR PREPARING SAME

Номер: WO2018174557A1

Автор: YUN, Eun Young, LEE, Woo Seok

Принадлежит:

The present invention relates to a functional fermented soybean lump using larvae and a method for preparing same and, more specifically, to a functional fermented soybean lump which shows excellent anti-inflammatory and antioxidant efficacies and is fermented by means of a yellow koji mold using white-spotted flower chafer, yellow mealworm beetle and dynastid beetle larvae which are animal proteins instead of soybeans which are vegetable proteins. The functional fermented soybean lump using larvae can be an alternative food resource for remedying food shortage crisis in the future, can provide various foods and added values by means of enabling development of edible-insect-processed foods, and can contribute to farm incomes.

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Номер записи: 31

15-12-2016 дата публикации

ANTI-MICROBIAL PEPTIDE, PERIPLANETASIN-2 ISOLATED FROM PERIPLANETA AMERICANA AND COMPOSITION THEREOF

Номер: KR101686428B1

Автор: HWANG, JAE SAM, YUN, EUN YOUNG, NAM, SUNG HEE, AHN, MI YOUNG, KIM, MI AE, KIM, SEONG HYUN, LEE, JOON HA, KIM, IN WOO

Принадлежит: REPUBLIC OF KOREA(MANAGEMENT : RURAL DEVELOPMENT ADMINISTRATION)

The present invention relates to a novel periplanetasin-2 peptide isolated from Periplaneta americana and a composition thereof. The peptide (periplanetasin-1) chemically synthesized by the present invention has a strong antimicrobial activity against gram-positive bacteria, gram-negative bacteria and fungi. The anti-microbial peptide according to the present invention has very low cytotoxicity and has strong anti-microbial activity, thereby being able to be used in developing antibiotics including anti-fungal agent, food preservatives, cosmetic preservatives, and drugs. COPYRIGHT KIPO 2016 (AA) Unit (μg/ml) ...

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Номер записи: 32

05-01-2016 дата публикации

TRANSGENIC SILKWORM PRODUCING BLUE FLUORESCENT SILK

Номер: KR1020160000527A

Автор: GOO, TAE WON, YUN, EUN YOUNG, CHOI, KWANG HO, KIM, SEONG RYUL, PARK, SEUNG WON, KIM, SUNG WAN

Принадлежит:

The present invention relates to a transgenic silkworm producing a blue fluorescent silk. The transgenic silkworm producing a blue fluorescent silk of the present invention is transformed with a recombinant expression vector comprising a gene construct in which a marker gene control promoter, a marker gene, a silkworm-derived fibroin promoter, and an Aequorea macrodactyla-derived blue fluorescent gene EBFPco are connected to be operable, thereby producing a blue fluorescent silk. According to the present invention, blue fluorescent silk which is eco-friendly and economical as the silk shows a natural deep blue color even under natural light and does not need extra dyeing, and can be effectively used as a raw material of luxury clothes, wall paper, etc. with a much higher added value compared to common silk as the silk shows a bright blue color in the darkness when exposed to a certain wavelength of light. COPYRIGHT KIPO 2016 ...

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Номер записи: 33

28-12-2017 дата публикации

FRUIT ICE BAR USING TENEBRIO MOLITOR AND MANUFACTURING METHOD THEREOF

Номер: KR1020170142330A

Автор: YUN, EUN YOUNG, HWANG, JAE SAM, KIM, MI AE, KIM, HYUNG MI, KIM, SEONG HYEON, SHON, JIN YOUNG

Принадлежит:

The present invention relates to a fruit ice bar using a Tenebrio molitor and a manufacturing method thereof. The fruit ice bar includes 1-10 wt% of Tenebrio molitor powder in contrast to the entire wt% of the composition. Moreover, the present invention is excellently nutritious with a high content of protein and minerals, has a good mouthfeel, and is able to be taken through various routes besides meals, and moreover, the present invention has an excellent flavor while including an excellent effect of Tenebrio molitors, and thus, the present invention is able to be provided as supplementary food for patients or children who require the intake of high quality protein. COPYRIGHT KIPO 2018 ...

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Номер записи: 34

02-01-2023 дата публикации

비대칭형 멤브레인 및 상기 비대칭형 멤브레인을 이용한 멤브레인 배열구조, 그리고 상기 멤브레인 배열구조를 포함하는 액화가스 저장탱크

Номер: KR20230000309A

Автор: 윤용근, 임기호, 오병택, 조용범, 이영범, 한해철, 윤은영

Принадлежит:

... 액화가스를 저장할 수 있는 저장탱크(10)에 밀봉층을 형성하기 위한 멤브레인으로서, 일방향으로 연장되는 제1 연장부(31)와, 상기 제1 연장부(31)와는 상이한 방향으로 연장되는 제2 연장부(32)를 포함하며, 상기 제1 연장부(31)의 연장 길이는 상기 제2 연장부(32)의 연장 길이와 상이하여, 상기 제1 연장부(31)와 상기 제2 연장부(32)는 비대칭 형상을 이루는 비대칭형 멤브레인(30)이 제공될 수 있다.

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Номер записи: 35

30-08-2016 дата публикации

갈색거저리 유충 또는 이의 추출물을 유효성분으로 포함하는 당뇨 예방 또는 치료용 조성물

Номер: KR0101651908B1

Автор: 윤은영, 황재삼, 구태원, 김미애, 유미라, 윤영일

Принадлежит: 대한민국

... 본 발명은 갈색거저리(Tenebrio molitor) 유충 또는 이의 추출물을 유효성분으로 포함하는 당뇨 예방 또는 치료용 조성물에 관한 것이다. 본 발명의 당뇨 예방 및 치료용 약학적 조성물 또는 당뇨 예방 및 개선용 식품 조성물은 갈색거저리(Tenebrio molitor) 유충 또는 이의 추출물을 유효성분으로 함유하는 것이 특징이다. 본 발명에 의해 산화적 스트레스를 억제하여 췌장베타세포의 생존율을 증가시키며 더불어 인슐린의 분비를 증가시켜 혈당수치 감소효과를 나타내는 갈색거저리(Tenebrio molitor) 유충 또는 이의 추출물을 유효성분으로 포함하는 당뇨 예방 또는 치료용 조성물이 제공된다.

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Номер записи: 36

04-07-2017 дата публикации

갈색거저리를 이용한 곤충어묵 조성물 및 이의 제조방법

Номер: KR0101752253B1

Автор: 윤은영, 황재삼, 김미애, 김형미, 김진수, 이은주, 함혜진, 신경훈, 정미영

Принадлежит: 대한민국(농촌진흥청장), 연세대학교 산학협력단

... 본 발명은 갈색거저리를 이용한 곤충어묵 조성물 및 이의 제조방법에 관한 것이다. 본 발명의 곤충어묵 조성물은 갈색거저리(Tenebrio molitor) 분말이 조성물 전체 중량대비 10~20 중량%로 포함되는 것이 특징이다. 본 발명에 의해, 갈색거저리를 이용하여 균형잡힌 단백질 공급원이 공급됨과 동시에 식사가 저조한 환자들에게 적은 양으로도 효율적인 영양공급이 가능한 갈색거저리를 이용한 곤충어묵 조성물 및 이의 제조방법이 제공된다.

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Номер записи: 37

21-06-2018 дата публикации

호박벌유충번데기를 포함하는 봉군껍질 유래 N-글라이칸과 서양뒤영벌 일벌유래 N-글라이칸 및 이들의 용도

Номер: KR0101869793B1

Автор: 안미영, 황재삼, 윤형주, 윤은영, 김하정

Принадлежит: 대한민국

... 본 발명은 (Hex)3(HexNAc)2(dHex) (m/z1079.4)의 당쇄 구조를 가지는 호박벌(Bombus ignitus) 봉군 껍질 유래 N-글라이칸(N-glycan) 및 이를 포함하는 분획물; (Hex)6, (Hex)7, (Hex)10, (Hex)11, (Hex)12의 호박벌(Bombus ignitus) 봉군 껍질 유래 N-글라이칸(N-glycan) 및 (Hex)3(HexNAc)2(dHex)1(m/z1080.4)의 서양뒤영벌(Bombus terrestris) 일벌 유래 N-글라이칸(N-glycan); 및 상기 N-글라이칸(N-glycan) 또는 이를 포함하는 분획물을 유효성분으로 함유하는 혈관내피협착 방지 및 치료용 약학 조성물에 관한 것이다. 본 발명에 따른 호박벌유충번데기를 포함하는 봉군껍질 또는 서양뒤영벌 일벌 유래 N-글라이칸(N-glycan) 및 이를 포함하는 분획물은 그의 생물학적 활성이 알려짐에 따라 의약품, 화장품 및 기능성식품 소재로 사용할 수 있어 제약 및 기능성 분자로서의 가치를 가지며, 특히 혈관내피협착 방지 효과가 있어, 호박벌유충번데기를 포함하는 봉군껍질 또는 서양뒤영벌 일벌 유래 N-글라이칸(N-glycan) 의약품 개발을 가능케 함으로써, 양봉사육농가 소득 보전 및 국민보건향상에 기여할 수 있다.

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Номер записи: 38

23-04-2018 дата публикации

바퀴벌레에서 유래한 항균 펩타이드 페리플라네타신-6 및 그의 조성물

Номер: KR0101851134B1

Автор: 황재삼, 윤은영, 남성희, 안미영, 김미애, 김성현, 이준하, 김인우

Принадлежит: 대한민국

... 본 발명은 바퀴벌레로부터 분리한 신규한 페리플라네타신-6 펩타이드 및 그의 조성물에 관한 것이다. 본 발명에서 화학적으로 합성된 펩타이드는 그람 양성균, 그람 음성균 또는 진균류에 대한 강한 항균 작용을 나타내면서도 세포 독성이 거의 없기 때문에 항균제, 항진균제, 항생제, 식품 방부제, 화장품 보존제, 의약품 보존제, 장염 치료제 등으로 유용하게 사용할 수 있다.

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Номер записи: 39

14-12-2017 дата публикации

왕지네 유래 신규 화합물 및 이의 항혈전 용도

Номер: KR0101808196B1

Автор: 김미애, 황재삼, 윤은영, 김성현, 배종섭, 나민균, 이정인

Принадлежит: 대한민국(농촌진흥청장), 경북대학교 산학협력단, 충남대학교산학협력단

... 본 발명은 왕지네(Scolopendrasubspinipes)로부터 분리한 화학식 1, 화학식 2 및 화학식 3으로 표시되는 화합물, 또는 이들의 약학적으로 허용가능한 염을 유효성분으로 함유하는 항혈전, 항혈소판 및 항응고용 약학적 조성물에 관한 것으로서, 보다 상세하게는 화학식 1, 화학식 2 및 화학식 3으로 표시되는 화합물은 인간 제대정맥혈관내피세포(human umbilical vein endothelial cells, HUVECs)에서 활성화 부분 트롬보플라스틴 시간(activated partial thromboplastin time, aPTT) 및 프로트롬빈 시간(prothrombin time, PT)을 연장하고 트롬빈 및 활성화된 인자 X(activated factor X, FXa)를 억제하며, 트롬빈에 의해 촉매된 피브린 중합 및 혈소판 응집을 억제하고, 폐색전증 모델 및 동맥 혈전증 모델에서 항혈전 효과를 증진시키며, 단백질 키나아제 C(protein kinase C, PKC) 활성 및 칼슘 동원을 방지하고, 마우스에서 항응고 효과를 야기하며, 조직 플라스미노겐 활성화제(tissue plasminogen activator, t-PA)에 대한 플라스미노겐 활성화제 억제제-1(plasminogen activator inhibitor-1, PAI-1)의 비율을 감소시킴으로써, 항혈전제, 항혈소판제 및 항응고제의 유효성분으로 유용하게 사용될 수 있다.

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Номер записи: 40

27-05-2016 дата публикации

A New Lactoferricin-like peptide and its synthetic composition

Номер: KR0101624688B1

Автор: 황재삼, 윤은영, 남성희, 안미영, 김미애, 이준하, 김인우, 김상희, 이동건, 이원영, 최혜민

Принадлежит: 대한민국(농촌진흥청장), 경북대학교 산학협력단

... 본 발명은 신규한 락토페리신 유사 항진균 펩타이드 및 그의 조성물에 관한 것이다. 본 발명의 항진균 펩타이드는 서열번호 2로 표현되며, 서열번호 1로 표현되는 펩타이드의 유전자에서 연역된 아미노산에서 합성된 것이 특징이다. 본 발명에 의해, 왕지네로부터 분리한 신규 락토페리신 유사 항진균 펩타이드 및 그의 조성물이 제공됨에 따라, 세포 독성이 없고 탁월한 항진균 활성을 나타냄과 동시에 인체에 안전한 항진균 제제용 항생제, 식품 방부제, 화장품 보존제 및 의약품 등을 제공할 수 있게 된다.

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Номер записи: 41

04-07-2017 дата публикации

PISTON FOR SWASH PLATE TYPE COMPRESSOR, MANUFACTURING APPARATUS AND MANUFACTURING METHOD THEREOF

Номер: KR1020170076425A

Автор: KWAK, JUNG MIN, KIM, KYUNG TAE, SEOK, JAE BIN, YUN, EUN YOUNG, YIM, DONG WON

Принадлежит:

The present invention relates to a piston for a swash plate type compressor which is able to maintain oil between an outer circumferential surface of a piston ring and an inner circumferential surface of a bore as much as possible even when oil is not smoothly provided to an interior of a compressor. To this end, the piston for the swash plate type compressor which reciprocates in a cylinder bore by rotation of a swash plate, comprises: a piston head; and a piston ring provided in the piston head and contacting to the inner circumferential surface of the cylinder bore, wherein the outer circumferential surface of the piston ring opposing to the inner circumferential surface of the cylinder bore is formed with an oil groove. COPYRIGHT KIPO 2017 ...

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Номер записи: 42

15-06-2016 дата публикации

An anti-microbial peptide Scolopendrasin-7 isolated from the Scolopendra subspinipes mutilans and its synthetic peptide

Номер: KR0101629386B1

Автор: 황재삼, 윤은영, 남성희, 안미영, 김미애, 이준하, 김인우, 김상희

Принадлежит: 대한민국

... 본 발명은 왕지네로부터 유래한 신규 항균 펩타이드 스콜로펜드라신-7 및 그의 조성물에 관한 것이다.본 발명은 왕지네(Scolopendra subspinipes)로부터 유래되어 서열번호 1로 표현되는 아미노산 서열로 이루어진 항균 펩타이드가 제공된다.

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Номер записи: 43

21-07-2017 дата публикации

COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASES CONTAINING GRYLLOTALPA ORIENTALIS EXTRACT

Номер: KR101760035B1

Автор: YUN, EUN YOUNG, HWANG, JAE SAM, AHN, MI YOUNG, LEE, YOUNG BO, YOON, YOUNG IL

Принадлежит: REPUBLIC OF KOREA(MANAGEMENT : RURAL DEVELOPMENT ADMINISTRATION)

The present invention relates to a composition for preventing or treating inflammatory bowel diseases containing a Gryllotalpa orientalis extract. The Gryllotalpa orientalis extract increases survival rates of immunoreactivity-suppressed drosophila or wild type drosophila which has eaten inflammatory bowel disease-inducible substances, and also inhibits expression of genes associated with inflammatory bowel diseases. Thus, the pharmaceutical compositions or functional health foods containing the Gryllotalpa orientalis extract ameliorate inflammatory bowel diseases such as Crohn disease and colitis ulcerativa which are hard to cure with common antiphlogistic drugs or anti-inflammatory drugs, thereby being useful as treatment compositions or functional health foods for ameliorating and preventing the diseases. COPYRIGHT KIPO 2017 ...

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Номер записи: 44

22-07-2015 дата публикации

TRANSGENIC SILKWORMS PRODUCING RECOMBINANT ANTIBACTERIAL PEPTIDE

Номер: KR1020150084152A

Автор: GOO, TAE WON, YUN, EUN YOUNG, CHOI, KWANG HO, KIM, SEONG RYUL, PARK, SEUNG WON, KANG, SEOK WOO, KIM, SUNG WAN

Принадлежит:

The present invention relates to transgenic silkworms producing recombination anti bacteria peptide cecropin B1 and a method for mass producing transgenic silkworm producing recombinant anti bacteria peptide cecropin B1 by using the transgenic silkworms and more specifically relates to manufacturing of recombinant expression vectors that can contain DNA constructs connected to operate DNS control promoters, marker DNA, silkworm promotoer and BmCecB1 synthetic DNA and transforming silkworms into the recombinant expression vectors, in order to produce transgenic silkworms that can produce silkworms containing anti bacteria peptide, thus enabling development of natural antibiotics and use as raw material for daily living products such as cosmetics or toothpastes as well as animal feeds. COPYRIGHT KIPO 2015 ...

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Номер записи: 45

07-01-2016 дата публикации

OXYA CHINENSIS SINUOSA EXTRACT HAVING ANTI-INFLAMMATORY ACTIVITIES AND COMPOSITION COMPRISING SAME

Номер: KR1020160001880A

Автор: YUN, EUN YOUNG, HWANG, JAE SAM, GOO, TAE WON, KIM, MI AE, LEE, YOUNG BO, YOON, YOUNG IL

Принадлежит:

The present invention relates to an Oxya chinensis sinuosa extract having anti-inflammatory activities, and to a composition comprising the same. The Oxya chinensis sinuosa extract having anti-inflammatory activities of the present invention is obtained by extracting Oxya chinensis sinuosa with ethanol. In different perspectives, provided are: a pharmaceutical composition comprising the Oxya chinensis sinuosa extract as an active ingredient for preventing and treating inflammatory diseases; and a food composition for alleviating inflammatory diseases. According to the present invention, the Oxya chinensis sinuosa extract having anti-inflammatory activities and a composition comprising the same have excellent safety without cytotoxicity, as natural resources derived from insects, and have anti-inflammatory effects by inhibiting the expression of an inflammation-related factor. Therefore, the extract and the composition can be used as an agent for preventing and treating inflammation which ...

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Номер записи: 46

12-10-2017 дата публикации

NOVEL COMPOUND ISOLATED FROM TENEBRIO MOLITOR AND METHOD FOR ISOLATING SAME

Номер: WO2017175915A1

Автор: YUN, Eun-Young, HWANG, Jae-Sam, KIM, Mi-Ae, BAEK, Min-Hee, JUN, Mi-Ra, YOUN, Kum-Ju, LEE, Seon-Ah

Принадлежит:

The present invention relates to a novel compound isolated from Tenebrio molitor and a method for isolating the same. The novel compound is expected to have a better effect in treating Alzheimer's since the novel compound is isolated from an ethyl acetate fraction showing an anti-Alzheimer's effect. Therefore, the novel compound can be easily used as a pharmaceutical composition for treating or preventing brain diseases of the elderly or as a health functional food.

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Номер записи: 47

17-03-2016 дата публикации

A Composition For Controlling the Growth of Nerve Cells containing lumbricusin peptide

Номер: KR0101603951B1

Автор: 황재삼, 윤은영, 남성희, 안미영, 이준하, 김인우, 권용남, 김호, 이민범, 남승택, 김대홍, 박미정

Принадлежит: 대한민국(농촌진흥청장), 대진대학교 산학협력단

... 본 발명은 룸브리쿠신 펩타이드를 유효성분으로 함유하는 신경세포 성장 조절용 조성물에 관한 것이다. 본 발명에서는 서열번호 1의 아미노산 배열로 이루어지며, 신경세포의 성장을 촉진하는 조절자인 룸브리쿠신 펩타이드(lumbricusin peptide)를 유효성분으로 함유하는 퇴행성 신경 질환의 치료용 조성물을 제공하는 것이 특징이다. 본 발명에 의해, 별다른 부작용없이 신경세포 성장과 증식을 촉진하거나 세포사멸 과정을 억제할 수 있는 새로운 신경세포 성장 조절용 조성물이 제공될 수 있어, 퇴행성 신경질환의 치료를 위한 비용이 저렴하면서 부작용이 없는 새로운 치료제의 개발 가능성을 제공한다는 등의 현저한 효과를 제공할 수 있게 된다.

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Номер записи: 48

02-05-2017 дата публикации

ANTIMICROBIAL PEPTIDE, PERIPLANETASIN-3, ISOLATED FROM COCKROACHES AND COMPOSITION THEREOF

Номер: KR1020170046302A

Автор: HWANG, JAE SAM, YUN, EUN YOUNG, NAM, SUNG HEE, AHN, MI YOUNG, KIM, MI AE, KIM, SEONG HYUN, LEE, JOON HA, KIM, IN WOO

Принадлежит:

The present invention relates to an antimicrobial peptide, periplanetasin-3, isolated from cockroaches and to a composition thereof. Periplanetasin-3, which is chemically synthesized by the present invention, has a strong antimicrobial activity against gram-positive bacteria, gram-negative bacteria, and fungi. The antimicrobial peptide according to the present invention has a minor cytotoxicity and strong antimicrobial activity, and therefore, the antimicrobial peptide can be used for developing antibiotics including antimycotics, preservatives for foods, preservatives for cosmetics, and medicines. COPYRIGHT KIPO 2017 (AA) Unit (μg/ml) ...

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Номер записи: 49

18-05-2016 дата публикации

ANTIMICROBIAL PEPTIDE SCOLOPENDRASIN-7 ISOLATED FROM SCOLOPENDRA SUBSPINIPES AND COMPOSITION THEREOF

Номер: KR1020160055343A

Автор: HWANG, JAE SAM, YUN, EUN YOUNG, NAM, SUNG HEE, AHN, MI YOUNG, KIM, MI AE, LEE, JOON HA, KIM, IN WOO, KIM, SAGN HEE

Принадлежит:

The present invention relates to a novel antimicrobial peptide scolopendrasin-7 isolated from Scolopendra subspinipes and a composition thereof. More specifically, provided is an antimicrobial peptide which is isolated from Scolopendra subspinipes and is composed of an amino acid sequence represented by sequence number 1. COPYRIGHT KIPO 2016 (AA) Scolopendrasin-7 (BB) Unit(μg /ml) ...

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Номер записи: 50

06-03-2018 дата публикации

ANTIBACTERIAL PEPTIDE PERIPLANETASIN-5 DERIVED FROM COCKROACH, AND COMPOSITION THEREOF

Номер: KR1020180022011A

Автор: HWANG, JAE SAM, YUN, EUN YOUNG, NAM, SUNG HEE, AHN, MI YOUNG, KIM, MI AE, KIM, SEONG HYUN, LEE, JOON HA, KIM, IN WOO

Принадлежит:

The present invention relates to a novel periplanetasin-5 peptide isolated from cockroach, and a composition thereof. More specifically, the present invention relates to a novel periplanetasin-5 peptide isolated from cockroach, and a composition thereof. The peptide which is chemically synthesized shows strong antibacterial functions against gram positive bacteria, gram negative bacteria, and fungi with little cytotoxicity, thereby being useful as antibacterial agents, antifungal agents, antibiotics, food preservatives, cosmetic preservatives, drug preservatives, and treatment agents for enteritis. COPYRIGHT KIPO 2018 (AA) Unit (μg/ml) ...

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Номер записи: 51

29-09-2016 дата публикации

곤충 엔-글라이칸 및 이의 용도

Номер: KR0101660381B1

Автор: 안미영, 황재삼, 김미애, 윤은영

Принадлежит: 대한민국

... 본 발명은 하나 이상의 Hex 및/또는 HexGlcNAc로 구성된 특정 당쇄 구조를 가지는 귀뚜라미(Gryllus bimaculatus), 매미눈꽃동충하초(Isaria sinclairii), 강랑(Catharsius molossus), 맹충(Tabanus bivittatus) 또는 광대노린재(Poecilocoris lewisi) 유래 곤충 N-글라이칸(N-glycan), 이를 포함하는 약학 조성물, 기능성 식품 및 화장료용 조성물에 관한 것이다. 본 발명에 따른 하나 이상의 Hex 및/또는 HexGlcNAc로 구성된 특정 당쇄 구조를 가진 곤충 N-글라이칸(N-glycan) 및 이를 포함하는 글라이코자미노글라이칸의 분획물은 생물학적 활성이 알려짐에 따라 의약품, 화장품 및 기능성식품 소재로 사용할 수 있어, 제약 및 기능성 분자로서의 가치를 가지며, 특히 혈관신생 억제능 또는 혈관확장반응의 기능장애에 의한 질환 치료효과가 있어, 다양한 곤충유래 N-글라이칸(N-glycan) 의약품 개발을 가능케함으로써, 곤충사육농가 소득 보전 및 국민보건향상에 기여할 수 있다.

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Номер записи: 52

18-04-2016 дата публикации

COMPOSITION FOR PREVENTING OR TREATING RHEUMATOID ARTHRITIS COMPRISING EXTRACT OF ALLOMYRINA DICHOTOMA AS ACTIVE INGREDIENT

Номер: KR1020160041105A

Автор: YUN, EUN YOUNG, HWANG, JAE SAM, GOO, TAE WON, KIM, MI AE, YOON, YOUNG IL

Принадлежит:

The present invention relates to a composition for preventing or treating rheumatoid arthritis comprising extract of Allomyrina dichotoma as an active ingredient. The method for preparing the extract of Allomyrina dichotoma having an anti-rheumatoid arthritis effect according to the present invention includes: a first step of starving Allomyrina dichotoma for 2-3 days and allowing Allomyrina dichotoma to defecate, followed by sterilization, freeze-drying and pulverization; a second step of mixing the pulverized material with ethanol to provide a mixed liquid of Allomyrina dichotoma; a third step of refining the mixed liquid of Allomyrina dichotoma with an ultrasonic pulverizer; and a fourth step of subjecting the refined mixed liquid of Allomyrina dichotoma to centrifugal separation and collecting the supernatant, followed by filtering. The resultant extract of Allomyrina dichotoma has an anti-rheumatoid arthritis effect through the inhibition of osteoclast differentiation. The present ...

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Номер записи: 53

11-05-2015 дата публикации

PHARMACEUTICAL COMPOSITION INCLUDING ALLOMYRINA DICHOTOMA AS ACTIVE INGREDIENT FOR PREVENTING AND TREATING ALZHEIMER′S AND FOOD COMPOSITION FOR ALLEVIATING ALZHEIMER′S

Номер: KR1020150050716A

Автор: YUN, EUN YOUNG, HWANG, JAE SAM, GOO, TAE WON, YOON, YOUNG IL, JUN, MI RA, YOUN, KUM JU, KIM, JI YOUNG

Принадлежит:

The present invention relates to a pharmaceutical composition including Allomyrina dichotoma as an active ingredient for preventing and treating Alzheimer′s and to a food composition for alleviating Alzheimer′s. A method for producing an Allomyrina dichotoma fragment having an anti-Alzheimer′s effect of the present invention comprises: a first step of pulverizing frozen and dried Allomyrina dichotoma; a second step of producing an Allomyrina dichotoma extraction liquid by mixing the Allomyrina dichotoma pulverized in the first step with a solvent; a third step of adding a solvent consisting of water and hexane to be mixed with the Allomyrina dichotoma extraction liquid produced from the second step, and separating only a hexane layer; and a fourth step of adding a solvent consisting of water and ethyl acetate (EtOAc) to be mixed with the Allomyrina dichotoma extraction liquid produced from the second step, and separating only ethyl acetate (EtOAc). According to a present invention, provided ...

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Номер записи: 54

26-01-2012 дата публикации

CATIONIC LIPID, A PRODUCTION METHOD FOR THE SAME AND A VEHICLE HAVING CELL PENETRATING PROPERTIES COMPRISING THE SAME

Номер: WO2012011693A3

Автор: PARK, Myung-Ok, YOON, Eun Young

Принадлежит:

Provided are a cationic lipid, a production method for the same and a vehicle comprising the same. The present invention can provide: a cationic lipid which improves the efficiency with which various anionic target compounds such as drugs, anticancer agents and nucleic acids are delivered into cells or into a body while also increasing safety as the cationic lipid is not toxic inside cells; a production method for the same; and a vehicle comprising the same.

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Номер записи: 55

12-09-2016 дата публикации

갈색거저리 유충의 추출물 또는 갈색거저리 유충의 현탁액을 유효성분으로 포함하는 비만 예방 또는 치료용 조성물

Номер: KR0101651907B1

Автор: 윤은영, 황재삼, 구태원, 김미애, 정미연

Принадлежит: 대한민국

... 본 발명은 갈색거저리 유충의 추출물 또는 갈색거저리 유충의 현탁액을 유효성분으로 포함하는 비만 예방 또는 치료용 조성물에 관한 것이다. 본 발명의 항비만효과를 갖는 갈색거저리 유충 추출물의 제조방법은, 동결건조된 갈색거저리 유충을 분쇄시키는 제1단계, 상기 제1단계에서 제조된 갈색거저리 유충 분말과 에탄올을 혼합하여 갈색거저리 혼합액을 제조하는 제2단계, 상기 제2단계에서 제조된 갈색거저리 혼합액을 초음파 분쇄기로 미세화시키는 제3단계 및, 상기 제3단계에서 미세화된 갈색거저리 혼합액을 원심분리 시킨 후, 상층액을 회수하고 이를 여과한 후 건조시켜, 항비만효과를 갖는 갈색거저리 유충 추출물을 제조하는 제4단계를 포함하는 것이 특징이다. 본 발명에 따른 갈색거저리 유충의 추출물 또는 갈색거저리 유충의 현탁액을 유효성분으로 포함하는 항비만 조성물은 부작용이 없고, 안전성이 우수할 뿐만 아니라 항비만 효능을 가짐으로써 비만 또는 비만과 연관된 질병의 예방 및 치료제로서 사용이 가능하다 ...

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Номер записи: 56

02-06-2017 дата публикации

벼메뚜기에서 유래한 항균 펩타이드 옥시야신-1 및 그의 조성물

Номер: KR0101743113B1

Автор: 황재삼, 윤은영, 안미영, 김미애, 김성현, 이준하, 김인우

Принадлежит: 대한민국

... 본 발명은 벼메뚜기로부터 분리한 신규한 옥시야신-1 펩타이드 및 그의 조성물에 관한 것이다. 본 발명에 의해 화학적으로 합성된 펩타이드(Oxyasin-1)는 그람 양성균, 그람 음성균 및 진균류에 대하여 강한 항균 작용을 나타내었다. 본 발명에 의한 상기 항균 펩타이드는 세포 독성이 미미하고, 항균활성이 강하므로 항진균제를 포함하는 항생제, 식품 방부제, 화장품 보존제, 의약품 개발 등으로 사용할 수 있다.

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Номер записи: 57

17-05-2017 дата публикации

ANTI-MICROBIAL PEPTIDE, OXYASIN-1 ISOLATED FROM OXYA CHINENSIS SINUOSA AND COMPOSITION THEREOF

Номер: KR1020170053879A

Автор: HWANG, JAE SAM, YUN, EUN YOUNG, AHN, MI YOUNG, KIM, MI AE, KIM, SEONG HYUN, LEE, JOON HA, KIM, IN WOO

Принадлежит:

The present invention relates to novel peptide, oxyasin-1, isolated from Oxya chinensis sinuosa and a composition thereof. The chemically synthesized oxyasin-1 of the present invention shows strong anti-microbial activity to gram-positive bacterium, gram-negative bacterium and fungi. The anti-microbial peptide has little cytotoxicity but strong anti-microbial activity, thereby being used for developing an antibiotic, a food preservative, a cosmetic preservative, a medicine, etc. comprising an antifungal agent. COPYRIGHT KIPO 2017 (AA) Unit (μg/ml) ...

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Номер записи: 58

01-12-2017 дата публикации

OXYA JAPONICA JAPONICA-DERIVED ANTIBACTERIAL PEPTIDE OXYASIN-4, AND COMPOSITION THEREOF

Номер: KR1020170131898A

Автор: HWANG, JAE SAM, YUN, EUN YOUNG, AHN, MI YOUNG, KIM, MI AE, KIM, SEONG HYUN, NAM, SUNG HEE, LEE, JOON HA, KIM, IN WOO

Принадлежит:

The present invention relates to a novel oxyasin-4 peptide isolated from Oxya japonica japonica, and a composition thereof. The chemically synthesized oxyasin-4 peptide shows strong antibacterial functions against gram positive bacteria, gram negative bacteria, or fungus with little cytotoxicity, thereby being useful as antibacterial agents, antifungal agents, antibiotics, and preservatives for foods, cosmetic products, and drugs. COPYRIGHT KIPO 2017 (AA) Unit (μg/ml) ...

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Номер записи: 59

25-05-2016 дата публикации

COMPOSITION COMPRISING SCOLOPENDRASIN-1 PEPTIDE AS ACTIVE INGREDIENT FOR PREVENTING AND TREATING ATOPIC DERMATITIS

Номер: KR1020160058315A

Автор: HWANG, JAE SAM, YUN, EUN YOUNG, NAM, SUNG HEE, AHN, MI YOUNG, KIM, MI AE, LEE, JOON HA, KIM, IN WOO, KIM, SAGN HEE, KANG, TAE JIN, LEE, GEUM SEON, LEE, KI MAN

Принадлежит:

The present invention relates to a composition comprising sclolopendrasin-1 peptide as an active ingredient for preventing and treating atopic dermatitis. The present invention provides a pharmaceutical composition for preventing and treating atopic dermatitis, which comprises scolopendrasin-1 peptide represented by sequence no. 1 and separated from Scolopendrasubspinipes. According to the present invention, it is possible to provide a composition for preventing and treating atopic dermatitis, which alleviates atopic dermatitis, reduces a level of immunoglobulin E and inhibits secretion of histamin and prostaglandin D2 that are inflammation mediators secreted through the activation of mast cells. COPYRIGHT KIPO 2016 ...

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Номер записи: 60

05-01-2017 дата публикации

METHOD FOR MANUFACTURING FUEL CELL SEPARATION PLATE AND FUEL CELL SEPARATION PLATE THEREOF

Номер: KR1020170001863A

Автор: HA, TAE GWEAN, BAE, GEUN DEUK, JANG, KYUNG SU, CHOI, WOO CHANG, CHOI, HYEON JIN, YUN, EUN YOUNG, KIM, KWANG HO, KWON, SE HUN

Принадлежит:

An objective of the present invention is to provide a fuel cell separation plate suitable for commercialization by applying a new coating material to the fuel cell separation plate, wherein the coating material is able to be manufactured at low costs and represents high corrosion resistance and high conductivity by overcoming all of step coverage, spring-back phenomenon due to thermal stress, and corrosion problems due to columnar grains. The present invention proposes meta/ceramic nanocomposite coating, and provides metal-ceramic nanocomposite coating materials, which are a novel nanocomposite coating material that prevents crystallization between metal particles and ceramic particles in a coating thin film by adjusting a high-conductivity metal and a high-conductivity ceramic material with a thickness of 1 nm or less, without using Si, Al, or B unlike conventional nanocomposite coatings, and has characteristics of representing low electrical resistance due to a high-conductivity matrix ...

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Номер записи: 61

30-11-2016 дата публикации

여왕벌 유래 엔-글라이칸 및 이의 용도

Номер: KR0101680644B1

Автор: 안미영, 황재삼, 윤형주, 윤은영

Принадлежит: 대한민국

... 본 발명은 Hex3HexNAc3dHex1 (1282.5 m/z) 또는 Hex4HexNAc3dHex1 (1485.6, m/z)의 당쇄 구조를 가지는 호박벌(Bombus ignitus) 여왕벌 유래 N-글라이칸(N-glycan) 및 이를 포함하는 분획물; Hex8 (1377.5 m/z)의 당쇄 구조를 가지는 서양뒤영벌(Bombus terrestris) 여왕벌 유래 N-글라이칸(N-glycan); 및 상기 N-글라이칸(N-glycan) 또는 이를 포함하는 분획물을 유효성분으로 함유하는 소염 또는 관절염 치료용 약학 조성물에 관한 것이다. 본 발명에 따른 여왕벌 유래 N-글라이칸(N-glycan) 및 이를 포함하는 분획물은 그의 생물학적 활성이 알려짐에 따라 의약품, 화장품 및 기능성식품 소재로 사용할 수 있어 제약 및 기능성 분자로서의 가치를 가지며, 특히 소염 또는 관절염 치료효과가 있어, 여왕벌 유래 N-글라이칸(N-glycan) 의약품 개발을 가능케함으로써, 양봉사육농가 소득 보전 및 국민보건향상에 기여할 수 있다.

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Номер записи: 62

18-04-2016 дата публикации

COMPOSITION FOR PREVENTING OR TREATING DIABETES, CONTAINING TENEBRIO MOLITOR LARVA OR EXTRACT THEREOF AS ACTIVE INGREDIENT

Номер: KR1020160041115A

Автор: YUN, EUN YOUNG, HWANG, JAE SAM, GOO, TAE WON, KIM, MI AE, YU, MI RA, YOON, YOUNG IL

Принадлежит:

The present invention relates to a composition for preventing or treating diabetes, containing Tenebrio molitor larva or an extract thereof as an active ingredient. More specifically, provided is a composition for preventing or treating diabetes, containing Tenebrio molitor larva or an extract thereof as an active ingredient. The pharmaceutical composition for preventing and treating diabetes or a food for preventing and treating diabetes contains the Tenebrio molitor larva or the extract thereof as the active ingredient. According to the present invention, oxidative stress is inhibited, and thus the survival rate of pancreatic beta cells increases. In addition, the composition or the food composition can also increase the secretion of insulin, thereby exhibiting effects of reducing blood glucose levels. COPYRIGHT KIPO 2016 ...

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Номер записи: 63

01-12-2017 дата публикации

ANTI-MICROBIAL PEPTIDE OXYASIN-3 ISOLATED FROM OXYA CHINENSIS SINUOSA AND COMPOSITION THEREOF

Номер: KR1020170131909A

Автор: HWANG, JAE SAM, YUN, EUN YOUNG, AHN, MI YOUNG, KIM, MI AE, KIM, SEONG HYUN, NAM, SUNG HEE, LEE, JOON HA, KIM, IN WOO

Принадлежит:

The present invention relates to a novel anti-microbial Oxyasin-3 peptide isolated from Oxya chinensis sinuosa and to a composition thereof. In the present invention, the chemically synthesized peptide, Oxyasin-3, has no cytotoxicity while exhibiting strong antibacterial activity against gram-positive bacteria, gram-negative bacteria or fungi, thereby being usefully used as antimicrobial agents, antifungal agents, antibiotics, food preservatives, cosmetic preservatives, pharmaceutical preservatives, and the like. COPYRIGHT KIPO 2017 (AA) Unit (μg/ml) ...

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Номер записи: 64

26-01-2012 дата публикации

CATIONIC LIPID, A PRODUCTION METHOD FOR THE SAME AND A VEHICLE HAVING CELL PENETRATING PROPERTIES COMPRISING THE SAME

Номер: KR2012011693A2

Автор: PARK, Myung-Ok, YOON, Eun Young

Принадлежит:

Provided are a cationic lipid, a production method for the same and a vehicle comprising the same. The present invention can provide: a cationic lipid which improves the efficiency with which various anionic target compounds such as drugs, anticancer agents and nucleic acids are delivered into cells or into a body while also increasing safety as the cationic lipid is not toxic inside cells; a production method for the same; and a vehicle comprising the same.

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Номер записи: 65

29-06-2016 дата публикации

TRANSGENIC SILKWORMS PRODUCING BLUE FLUORESCENT COCOONS

Номер: KR0101634275B1

Автор: 구태원, 윤은영, 최광호, 김성렬, 박승원, 김성완

Принадлежит: 대한민국

... 본 발명은 청색 형광 실크를 생산하는 형질전환 누에에 관한 것으로, 보다 상세하게는 표지 유전자 조절 프로모터, 표지 유전자, 누에 유래의 피브로인(Fibroin) 프로모터 및 해파리(Aequorea macrodactyla) 유래 청색 형광 유전자가 작동가능하게 연결된 유전자 컨스트럭트를 포함하는 재조합 발현벡터를 제작하여 상기 재조합 발현벡터로 누에를 형질전환시킴으로써 청색 형광 실크를 생산하는 형질전환 누에를 제조할 수 있으며, 상기 형질전환 누에가 생산하는 청색 형광 실크는 자연광에서도 엷은 천연의 청색을 나타내어 별도의 염색이 필요 없어 친환경적이고 경제적이며 특정 파장의 빛을 쏘이면 어둠 속에서 영롱한 청색을 나타내어 일반 실크에 비해 훨씬 고부가가치의 고급 패션의류나 벽지 등의 소재로 유용하게 사용될 수 있다.

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Номер записи: 66

07-11-2018 дата публикации

SEASONING COMPOSITION CONTAINING FERMENTED MEAL BEETLE LARVA

Номер: KR1020180121084A

Автор: KIM, MI AE, HWANG, JAE SAM, YUN, EUN YOUNG, SEO, MIN CHUL, KIM, SOO HEE, HWANG, IN KYEONG, SON, YANG JU, LEE, JI WON, YANG, SIN CHUL

Принадлежит:

The present invention relates to a seasoning composition containing fermented meal beetle larva. More specifically, the present invention relates to a fermented seasoning composition containing a solid or liquid fermented product obtained by fermenting meal beetle larva powder with Aspergillus oryzae. To this end, the seasoning composition of the present invention is a high protein source by using Aspergillus oryzae and is produced by fermenting powder of meal beetle larva known to have therapeutic or ameliorating effects on various diseases. In addition, the seasoning composition has taste and shapes similar to soy sauce or soybean paste which are fermented products of soybean, enables adjustment of sodium intake by having low salinity, and ensures excellent taste and aroma, thereby being able to be used as a seasoning effective in increasing health functionality and taste of foods. COPYRIGHT KIPO 2018 ...

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Номер записи: 67

26-10-2017 дата публикации

NOVEL HETEROCYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER

Номер: WO2017183927A1

Автор: PARK, Seong Jun, HEO, Jung Nyoung, KIM, Kwang-Rok, KIM, Sung Soo, LIM, Hwan Jung, LEE, Hyuk, CHANG, Sung Youn, KIM, Bum Tae, YOON, Eun Young, LIM, Byung Ho

Принадлежит:

The present invention relates to a novel heterocyclic compound, a method for preparing the same, and a pharmaceutical composition comprising the same as an active ingredient for preventing or treating cancer. The heterocyclic compound according to the present invention can significantly inhibit NEDD8-activating enzyme (NAE) or Sumo activating enzyme (SAE) at a concentration in a nanomolar unit, and thus the heterocyclic compound can be favorably used for a pharmaceutical composition containing the same as an active ingredient for preventing or treating cancer, for example, a disease associated with NEDD8-activating enzyme (NAE) or Sumo activating enzyme (SAE).

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Номер записи: 68

24-05-2016 дата публикации

NOVEL SCOLOPENDRASIN-4 PEPTIDE PROMOTING GROWTH OF LARGE INTESTINE EPITHELIAL CELLS AND COMPOSITION THEREOF

Номер: KR1020160057529A

Автор: HWANG, JAE SAM, YUN, EUN YOUNG, NAM, SUNG HEE, AHN, MI YOUNG, KIM, MI AE, LEE, JOON HA, KIM, IN WOO, KIM, SAGN HEE, KIM, HO, KIM, DAE HONG, LEE, IK HWAN, NAM, SEONG TAEK

Принадлежит:

The present invention relates to a novel scolopendrasin-4 peptide which promotes the growth of large intestine epithelial cells and a composition thereof. More specifically, the purpose of the present invention is to provide a peptide which promotes the growth of large intestine epithelial cells, wherein the peptide is synthesized from an amino acid which is represented by sequence number 1 and derived from a gene of a peptide isolated from Scolopendra subspinipes. According to the present invention, by providing the novel scolopendrasin-4 peptide which promotes the growth of large intestine epithelial cells, it is possible to provide a composition for preventing and treating inflammatory large bowel disease as a novel substance which improves the inflammatory large bowel without causing cytotoxicity. COPYRIGHT KIPO 2016 ...

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Номер записи: 69

08-05-2017 дата публикации

FAT ACCUMULATION INHIBITING USE OF QUEEN BOMBUS IGNITUS GLYCOSAMINOGLYCAN

Номер: KR1020170047544A

Автор: AHN, MI YOUNG, HWANG, JAE SAM, YOON, HYUNG JOO, YUN, EUN YOUNG, KIM, SUN JA, KIM, BAN JI

Принадлежит:

Glycosaminoglycan derived from queen Bombus ignitus inhibits in vivo abdominal fat accumulation during a high fat diet, reduces a cholesterol content, and reduces free fatty acid in plasma. Activated partial thromboplastin time (APTT) in plasma is extended, so blood coagulation is prevented and adhesion protein-related laminin existing in a hemangioendothelial part is inhibited. In addition, damage to the protein of blood globulin is inhibited, and lipoperoxide accumulation (MDA amount) of liver cells is inhibited. Moreover, when being seen at a cell level, nitric oxide (NO) is generated in hemangioendothelial cells to ensure vasorelaxation. Furthermore, it has been able to be confirmed that rise of blood pressure caused by a high fat diet can be prevented after the glycosaminoglycan has been administrated to a rat for a month. The glycosaminoglycan derived from queen Bombus ignitus provides a composition for inhibiting lipid accumulation, inhibiting cell membrane adhesive protein attachment ...

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Номер записи: 70

06-03-2018 дата публикации

ANTIMICROBIAL PEPTIDE PERIPLANETASIN-4 ISOLATED FROM BLATTODEA AND COMPOSITION THEREOF

Номер: KR1020180022007A

Автор: HWANG, JAE SAM, YUN, EUN YOUNG, NAM, SUNG HEE, AHN, MI YOUNG, KIM, MI AE, KIM, SEONG HYUN, LEE, JOON HA, KIM, IN WOO

Принадлежит:

The present invention relates to a novel peptide periplanetasin-4 isolated from Blattodea and to a composition thereof. In the present invention, the chemically synthesized peptide exhibits strong antimicrobial action against Gram-positive bacteria, Gram-negative bacteria or fungi, and has little cytotoxicity to be usefully used as antimicrobial agents, antifungal agents, antibiotics, food preservatives, cosmetic preservatives, pharmaceutical preservatives, enteritis therapeutic agents and the like. COPYRIGHT KIPO 2018 (AA) Unit (μg/ml) ...

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Номер записи: 71

07-02-2018 дата публикации

벼메뚜기에서 유래한 항균 펩타이드 옥시야신-3 및 그의 조성물

Номер: KR0101825952B1

Автор: 황재삼, 윤은영, 안미영, 김미애, 김성현, 남성희, 이준하, 김인우

Принадлежит: 대한민국

... 본 발명은 벼메뚜기로부터 분리한 신규한 옥시야신-3 펩타이드 및 그의 조성물에 관한 것이다. 본 발명에서 화학적으로 합성된 펩타이드(Oxyasin-3)는 그람 양성균, 그람 음성균 또는 진균류에 대한 강한 항균 작용을 나타내면서도 세포 독성이 없기 때문에 항균제, 항진균제, 항생제, 식품 방부제, 화장품 보존제, 의약품 보존제 등으로 유용하게 사용할 수 있다.

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Номер записи: 72

08-06-2017 дата публикации

벼메뚜기에서 유래한 항균 펩타이드 옥시야신-2 및 그의 조성물

Номер: KR0101740551B1

Автор: 황재삼, 윤은영, 안미영, 김미애, 김성현, 이준하, 김인우

Принадлежит: 대한민국

... 본 발명은 벼메뚜기로 부터 분리한 신규한 옥시야신-2 펩타이드 및 그의 조성물에 관한 것이다. 본 발명에 의해 화학적으로 합성된 펩타이드(Oxyasin-2)는 그람 양성균, 그람 음성균 및 진균류에 대하여 강한 항균 작용을 나타내었다. 본 발명에 의한 상기 항균 펩타이드는 세포 독성이 미미하고, 항균활성이 강하므로 항진균제를 포함하는 항생제, 식품 방부제, 화장품 보존제, 의약품 개발 등으로 사용할 수 있다.

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Номер записи: 73

13-12-2012 дата публикации

SWING LINK FOR A SCROLL COMPRESSOR AND METHOD FOR TREATING THE SURFACE OF SAME

Номер: WO2012169763A2

Автор: YOON, Eun Young, CHOI, Yong Wan, JOO, Sang Hyun, BAE, Jae Hyun, SHIN, Jin Young, LEE, Jae Wook

Принадлежит:

The present invention relates to a swing link for a scroll compressor, and more particularly, to a swing link for a scroll compressor having improved abrasion resistance, corrosion resistance, and durability, and to a method for treating the surface of the swing link. The method for treating the surface of the swing link for the scroll compressor, which involves treating the outer surface of the swing link for the scroll compressor having a cylindrical unit and a balance weight, comprises: a stress-removing step of removing internal stresses of the swing link; a normalizing step of smoothing the internal organization of the swing link; and a low-temperature nitrocarburizing step of leaving the swing link in a gaseous nitrocarburizing atmosphere in a nitrocarburizing furnace for a predetermined period of time and then cooling the swing link in an inactive nitrification furnace.

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Номер записи: 74

08-03-2017 дата публикации

CULTURE DEVICE OF CULTURING PROTOZOA BY SUPPLYING ORGANIC WASTE

Номер: KR1020170026311A

Автор: PARK, JAE YEON, MOON, SEUNG JOO, YOON, EUN YOUNG, KIM, HYO JUNG, JEONG, HAE JIN

Принадлежит:

The present invention relates to a culture tank of organic wastes, which stores marine microorganisms and a marine protist with organic wastes, analyzes the organic wastes by the marine microorganisms, and supplies the marine microorganisms reproduced by taking the organic wastes and cultures the marine protist. The culture tank of organic wastes comprises a discharge port arranged on one side of a lower portion in the culture tank of organic wastes and discharging undecomposed fiber of the accumulated organic wastes. COPYRIGHT KIPO 2017 ...

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Номер записи: 75

06-03-2018 дата публикации

ANTI-MICROBIAL PEPTIDE, PERIPLANETASIN-6 ISOLATED FROM BLATTODEA AND COMPOSITION THEREOF

Номер: KR1020180022013A

Автор: HWANG, JAE SAM, YUN, EUN YOUNG, NAM, SUNG HEE, AHN, MI YOUNG, KIM, MI AE, KIM, SEONG HYUN, LEE, JOON HA, KIM, IN WOO

Принадлежит:

The present invention relates to a novel periplanetasin-6 peptide isolated from Blattodea and to a composition thereof. In the present invention, the chemically synthesized peptide exhibits strong antimicrobial action against Gram-positive bacteria, Gram-negative bacteria or fungi, but has little cytotoxicity to be usefully used as antimicrobial agents, antifungal agents, antibiotics, food preservatives, cosmetic preservatives, pharmaceutical preservatives, enteritis therapeutic agents and the like. COPYRIGHT KIPO 2018 (AA) Unit (μg/ml) ...

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Номер записи: 76

19-05-2016 дата публикации

METHOD FOR PREPARING BLONANSERIN AND INTERMEDIATE THEREFOR

Номер: WO2016076573A2

Автор: LEE, Kyung-Jin, YOON, Eun-Young

Принадлежит:

The present invention relates to a method for producing high-purity blonanserin at a high yield under mild reaction conditions, and an intermediate used therefor.

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Номер записи: 77

19-05-2016 дата публикации

METHOD FOR PREPARING BLONANSERIN AND INTERMEDIATE THEREFOR

Номер: WO2016076573A3

Автор: LEE, Kyung-Jin, YOON, Eun-Young

Принадлежит:

The present invention relates to a method for producing high-purity blonanserin at a high yield under mild reaction conditions, and an intermediate used therefor.

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Номер записи: 78

18-07-2017 дата публикации

ANTITHROMBOTIC COMPOSITION CONTAINING COMPOUND ISOLATED FROM PROTAETIA BREVITARSIS SEULENSIS LARVA

Номер: KR101758718B1

Автор: KIM, MI AE, HWANG, JAE SAM, YUN, EUN YOUNG, KIM, SEONG HYUN, BAE, JONG SUP, NA, MIN KYUN, LEE, JUNG IN

Принадлежит: REPUBLIC OF KOREA(MANAGEMENT : RURAL DEVELOPMENT ADMINISTRATION), KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC)

The present invention relates to an antithrombotic, antiplatelet, or anticoagulant composition containing one or more compounds selected from 5-hydroxyindolin-2-one (compound 1) isolated from Protaetia brevitarsis seulensis and 1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (compound 2). The compound suppresses an exogenic and endogenetic blood coagulation pathway by suppressing FXa and thrombin production in HUVEC, suppresses secretion of PAI-1 induced by TNF-α, suppresses platelet coagulation in vivo and in vitro, and specifically prevents protein kinase C and calcium kinetics. Thus, the compound can be useful as a pharmaceutical composition or health functional food for treating or preventing blood vessel diseases related to blood coagulation. COPYRIGHT KIPO 2017 ...

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Номер записи: 79

12-07-2016 дата публикации

METHOD FOR PREPARING FERMENTED CITRUS MATERIAL HAVING IMPROVED BIOACTIVITY

Номер: KR1020160083781A

Автор: LEE, SEUNG CHEOL, CHOI, SO YEON, KIM, SI KYUNG, YOUN, UN YOUNG, CHOI, NACK SHICK, MUN, MI SUN, KIM, MAN SUK, MUN, JONG CHEON

Принадлежит:

The present invention relates to a method for preparing a fermented citrus material having improved bioactivity, and more specifically, to a method for preparing a fermented citrus material, which ferments citrus using a lactic acid bacteria selected from the group consisting of Lactobacillus sakei (KACC92032P), Pediococcus acidilactici (KACC92031P), and Leuconostoc mesenteroides (KCTC3505) to produce a fermented citrus material having acetylcholinesterase inhibition activity, angiotensin converting enzyme inhibition activity or antibacterial activity. The present invention further relates to a fermented material prepared by the present method and a food composition comprising this fermented material. According to the present invention, the fermented citrus material having excellent acetylcholinesterase inhibition activity, angiotensin converting enzyme inhibition activity or antibacterial activity can be prepared. Also, the excellent bioactivity of the present fermented citrus material ...

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Номер записи: 80

17-01-2018 дата публикации

ANTITHROMBOTIC COMPOSITION COMPRISING COMPOUND ISOLATED FROM PROTAETIA BREVITARSIS SEULENSIS LARVA

Номер: KR1020180006297A

Автор: KIM, MI AE, HWANG, JAE SAM, YUN, EUN YOUNG, KIM, SEONG HYUN, BAE, JONG SUP, NA, MIN KYUN, LEE, JUNG IN

Принадлежит:

The present invention relates to a composition for antithrombosis, antiplatelet or anticoagulation comprising a compound selected from the group consisting of 5-hydroxyindolin-2-one (compound 1) and 1-methyl-1, 2, 3, 4-tetrahydro-β-carboline-3-carboxylic acid (compound 2) isolated from Protaetia brevitarsis seulensis. The compound inhibits an exogenous and endogenous blood coagulation pathway through inhibition of FXa and thrombin production in HUVEC, suppresses the secretion of PAI-1 induced by TNF-α, inhibits platelet aggregation in vitro, and specifically prevents protein kinase C and calcium mobilization, thereby being useful as a pharmaceutical composition or a health functional food for the treatment or prevention of vascular diseases associated with such blood coagulation. COPYRIGHT KIPO 2018 ...

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Номер записи: 81

04-07-2017 дата публикации

SWASH PLATE OF SWASH TYPE COMPRESSOR

Номер: KR1020170076410A

Автор: KWAK, JUNG MIN, KIM, KYUNG TAE, SEOK, JAE BIN, YUN, EUN YOUNG, YIM, DONG WON

Принадлежит:

The present invention relates to a swash plate of a swash type compressor which is able to minimize a joint generated by being latched to an edge of a piston bridge. According to the present invention, the swash plate of a swash type compressor to which an insertion object recognized by an external sensor is fixed comprises: a swash plate body; and an insertion groove formed in an outer circumferential surface of the swash plate body and inserted with the insertion object, wherein the insertion groove includes a front end portion where the insertion object is located in advance in a direction which the insertion object is inserted, and a size of the front end portion is increased toward the outer circumferential surface of the swash plate body. COPYRIGHT KIPO 2017 ...

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Номер записи: 82

23-06-2017 дата публикации

SWASH PLATE TYPE COMPRESSOR WITH OIL SEPARATOR

Номер: KR1020170071048A

Автор: KWAK, JUNG MIN, SEOK, JAE BIN, KIM, KYUNG TAE, YUN, EUN YOUNG, YIM, DONG WON

Принадлежит:

A swash plate type compressor comprises: a housing having a cylinder block therein; a driving shaft mounted onto the housing to be rotated; a swash plate coupled to the driving shaft to be rotated with the driving shaft and arranged in the housing; a plurality of pistons enabling suction, extrusion, and discharge of a refrigerant while reciprocating to correspond to rotation of the swash plate; a front head coupled to a front side of the housing; a rear head coupled to a rear side of the housing and formed with a discharge port; an oil separator arranged in the discharge port of the rear head so as to separate oil mixed in the refrigerant; an oil chamber for storing the oil separated by the oil separator; and an oil introduction path for introducing the oil stored in the oil chamber into the housing, wherein the oil introduction path is formed on the cylinder block. COPYRIGHT KIPO 2017 ...

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Номер записи: 83

19-05-2017 дата публикации

SWALLOWING FOOD USING TENEBRIO MOLITOR AND MANUFACTURING METHOD THEREOF

Номер: KR1020170055062A

Автор: YUN, EUN YOUNG, HWANG, JAE SAM, KIM, MI AE, CHUNG, HYUNG KEUN, LEE, SEA YOUNG, LEE, JUNG EUN, WOO, SUNG MIN

Принадлежит:

The present invention relates to a swallowing food using Tenebrio molitor and a manufacturing method thereof. The swallowing food comprises Tenebrio molitor as an active ingredient. The Tenebrio molitor is used in a powder type. By using Tenebrio molitor as a protein source instead of beef, the swallowing food is a balanced nourishing food in a nutrition and functional manner which can be supplied to a person who has a swallowing problem. Also, due to anticancer activity of Tenebrio molitor, the swallowing food can be applied as a therapeutic diet. COPYRIGHT KIPO 2017 (AA) Example 1 (BB) Comparative example 1 (CC) Comparative example 2 (DD) Comparative example 3 ...

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Номер записи: 84

25-09-2017 дата публикации

COMPOSITION FOR PROMOTING HAIR GROWTH OR PREVENTING HAIR LOSS CONTAINING MEAL BEETLE EXTRACT

Номер: KR101780934B1

Автор: YUN, EUN YOUNG, HWANG, JAE SAM, KIM, MI AE, SEO, MIN CHUL, YOON, YOUNG IL

Принадлежит: REPUBLIC OF KOREA(MANAGEMENT : RURAL DEVELOPMENT ADMINISTRATION)

The present invention relates to a composition for promoting hair growth or preventing hair loss containing a meal beetle extract. The meal beetle extract excellently regulates cell viability in human keratinocytes, human dermal papilla cells, and fibroblasts, as well as cell proliferation effects and cytokines associated with hair loss. Further, the meal beetle extract is highly stable and safe to use compared to existing compositions for promoting hair growth or preventing hair loss, thereby ensuring easy usability as functional health foods, cosmetic ingredients, pharmaceutical compositions containing the same, and compositions for promoting hair growth or preventing hair loss. COPYRIGHT KIPO 2017 ...

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Номер записи: 85

27-05-2016 дата публикации

A New Scolopendrasin-5 peptide isolated from the Scolopendra subspinipes and its synthetic composition

Номер: KR0101624632B1

Автор: 황재삼, 윤은영, 남성희, 안미영, 김미애, 이준하, 김인우, 김상희

Принадлежит: 대한민국

... 본 발명은 왕지네로부터 분리한 신규 스콜로펜드라신-5 펩타이드 및 그의 조성물에 관한 것이다. 본 발명은 서열번호 1으로 표현되며, 왕지네(Scolopendra subspinipes)로부터 분리한 펩타이드의 유전자에서 연역된 아미노산에서 합성된 펩타이드를 제공하고자 한다. 본 발명에 의해, 왕지네로부터 분리한 신규 스콜로펜드라신-5 펩타이드 및 그의 조성물이 제공됨에 따라, 세포 독성이 없고 항균 및 항진균 활성을 나타냄과 동시에 인체에 안전한 항생제, 식품 방부제, 화장품 보존제, 의약품 등이 제공하게 된다.

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Номер записи: 86

29-06-2016 дата публикации

A COMPOSITION FOR TREATMENT AND PREVENTION OF ARTERIOSCLEROSIS FROM BOMBUS TERRESTRIS

Номер: KR0101634268B1

Автор: 안미영, 황재삼, 윤형주, 윤은영

Принадлежит: 대한민국

... 본 발명은 서열번호 1 내지 14의 아미노산 서열로 표시되는 펩티드로 구성된 군으로부터 선택되는 하나의 펩티드를 활성 부분으로 포함하는 뒤영벌(Bombus terrestris) 유충 유래 폴리펩티드를 유효성분으로 하는 동맥경화, 발기부전 치료 또는 예방용 조성물, 및 혈관질환 개선용 건강식품에 관한 것이다. 본 발명에 따른 뒤영벌 유충 유래 단백질의 N 말단 펩티드를 활성 부분으로 하는 단백질은 혈관내피세포 및 비장세포에서 산화질소 생성조절능이 있기 때문에, 이로 인한 혈관확장 효과를 기대할 수 있으며, 따라서 혈관확장 효과가 치료효능으로 필요한 동맥경화 및 발기부전과 같은 혈관질환 예방, 치료 및 개선용으로 유용하다.

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Номер записи: 87

31-01-2017 дата публикации

EXTRACT OF POPILLIA FLAVOSELLATA HAVING ANTI-INFLAMMATORY ACTIVITY AND COMPOSITION COMPRISING SAME

Номер: KR101700605B1

Автор: YUN, EUN YOUNG, HWANG, JAE SAM, KIM, MI AE, LEE, YOUNG BO, YOON, YOUNG IL

Принадлежит: REPUBLIC OF KOREA(MANAGEMENT : RURAL DEVELOPMENT ADMINISTRATION)

The present invention relates to an extract of Popillia flavosellata and compositions comprising the same. The extract of Popillia flavosellata of the present invention is obtained by extracting Popillia flavosellata with a solvent, and another aspect of the present invention provides a pharmaceutical composition for preventing and treating inflammatory diseases or a food composition for preventing and alleviating inflammatory diseases, all of which comprise the extract of Popillia flavosellata as an effective component. The extract of Popillia flavosellata having anti-inflammatory activity and compositions comprising the same have negligible cytotoxicity as insect-derived natural resources and thus are safe, and exhibit anti-inflammatory effects by inhibiting the expression of inflammation-related factors and thus can be used as an agent for preventing or treating inflammations conducive to various diseases. COPYRIGHT KIPO 2017 ...

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Номер записи: 88

12-12-2017 дата публикации

METHOD FOR MANUFACTURING POWDER OF TENEBRIO MOLITOR LARVA USING WET-GRINDING AND SPRAY DRYING METHOD

Номер: KR101808028B1

Автор: YUN, EUN YOUNG, HWANG, JAE SAM, KIM, MI AE, LEE, JONG CHUL, KIM, MIN SOO, KIM, SUNG TAE, HAN, SANG JIN, LEE, JIN SUN, AHN, EUN JI

Принадлежит: REPUBLIC OF KOREA(MANAGEMENT : RURAL DEVELOPMENT ADMINISTRATION), HANMI NATURAL COMPANY LIMITED

The present invention relates to a method for manufacturing a powder of Tenebrio molitor larva using wet-grinding and spray drying methods, wherein the powder of Tenebrio molitor larva manufactured by the method of the present invention, compared with a conventional brown larvae powder manufactured by a direct larval drying method and a mechanical pulverization method, has excellent powdery fluidity and particle size which are good to be manufactured for various foods or pharmaceutical compositions, and does not get rancid while containing a large amount of unsaturated fatty acid which is effective for enhancing the physiological activity. COPYRIGHT KIPO 2018 ...

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Номер записи: 89

31-10-2017 дата публикации

NOVEL HETEROCYCLIC COMPOUND, PREPARATION METHOD OF SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS EFFECTIVE COMPONENT

Номер: KR1020170120521A

Автор: PARK, SEONG JUN, HEO, JUNG NYOUNG, KIM, KWANG ROK, KIM, SUNG SOO, LIM, HWAN JUNG, LEE, HYUK, CHANG, SUNG YOUN, KIM, BUM TAE, YOON, EUN YOUNG, LIM, BYUNG HO

Принадлежит:

The present invention relates to a novel heterocyclic compound, a preparation method of the same, and a pharmaceutical composition for preventing or treating diseases related to NEDD8-activating enzyme (NAE) or SUMO-activating enzyme (SAE) comprising the same as an effective component. The heterocyclic compound according to the present invention can effectively suppress NAE or SAE at nano-mole concentrations, and thus the pharmaceutical composition comprising the same as an effective component may be beneficially used for preventing or treating diseases related to NAE or SAE, such as cancers. COPYRIGHT KIPO 2017 ...

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Номер записи: 90

20-12-2016 дата публикации

ANTIBACTERIAL PEPTIDE PERIPLANETASIN-1 DERIVED FROM COCKROACH AND COMPOSITION THEREOF

Номер: KR1020160145216A

Автор: HWANG, JAE SAM, YUN, EUN YOUNG, NAM, SUNG HEE, AHN, MI YOUNG, KIM, MI AE, KIM, SEONG HYUN, LEE, JOON HA, KIM, IN WOO

Принадлежит:

The present invention relates to a novel periplanetasin-1 peptide isolated from cockroach, and to a composition thereof. According to the present invention, the periplanetasin-1 peptide which is chemically synthesized shows strong antibacterial effects against gram positive bacteria, gram negative bacteria, and fungus, causes little cytotoxicity, and strong antibacterial activities. Thus, the periplanetasin-1 peptide can be used for developing drugs, preservatives, food preservatives, antibiotics including antifungal agent. COPYRIGHT KIPO 2016 (AA) Unit (μg/ml) ...

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Номер записи: 91

19-05-2017 дата публикации

INSECT FISH CAKE COMPOSITION USING TENEBRIO MOLITOR AND METHOD FOR MANUFACTURING THEREOF

Номер: KR1020170055047A

Автор: YUN, EUN YOUNG, HWANG, JAE SAM, KIM, MI AE, KIM, HYUNG MI, KIM, JIN SOU, LEE, EUN JOO, HAM, HYE JIN, SHIN, KYUNG HUN, JEONG, MI YOUNG

Принадлежит:

The present invention relates to an insect fish cake composition using Tenebrio molitor and a method for manufacturing thereof. The insect fish cake composition of the present invention contains 10-20 wt% of Tenebrio molitor powder compared to the total weight of the composition. According to the present invention, a balanced protein source is provided using Tenebrio molitor, and nutrients are effectively supplied to patients who eat a small amount of food with only a small quantity. COPYRIGHT KIPO 2017 (AA) Example 1 (BB) Comparative example 2 ...

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Номер записи: 92

18-05-2018 дата публикации

ANTI-MICROBIAL PEPTIDE PROTAETIAMYCINE 2 ISOLATED FROM PROTAETIA BREVITARSIS AND COMPOSITION THEREOF

Номер: KR1020180052181A

Автор: HWANG, JAE SAM, YUN, EUN YOUNG, NAM, SUNG HEE, AHN, MI YOUNG, KIM, MI AE, KIM, SEONG HYUN, LEE, JOON HA, KIM, IN WOO

Принадлежит:

The present invention relates to a novel peptide protaetiamycine 2 isolated from Protaetia brevitarsis and to a composition thereof. The chemically synthesized peptides in the present invention exhibit strong antibacterial action to gram-positive bacteria, gram-negative bacteria or fungi, but show little cytotoxicity, thereby being usefully used as antimicrobial agents, antifungal agents, antibiotics, food preservatives, cosmetic preservatives, pharmaceutical preservatives, enteritis therapeutic agents and the like. COPYRIGHT KIPO 2018 (AA) Unit ...

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Номер записи: 93

27-04-2018 дата публикации

N-GLYCAN DERIVED FROM HONEYCOMB SKIN INCLUDING BOMBUS IGNITUS LARVAE AND PUPAE, N-GLYCAN DERIVED FROM BOMBUS TERRESTRIS WORKER BEES, AND USES THEREOF

Номер: KR1020180043225A

Автор: AHN MI YOUNG, HWANG JAE SAM, YOON HYUNG JOO, YUN EUN YOUNG, KIM SUN JA

Принадлежит:

The present invention relates to: N-glycan derived from Bombus ignitus honeycomb skin having a sugar chain structure of (Hex)3(HexNAc)2(dHex)(m/z1079.4), and a fraction containing the same; N-glycan derived from Bombus ignitus honeycomb skin of (Hex)6, (Hex)7, (Hex)10, (Hex)11, (Hex)12, and N-glycan derived from Bombus terrestris worker bees of (Hex)3(HexNAc)2(dHex)1(m/z1080.4); and a pharmaceutical composition for preventing and treating hemadostenosis, wherein the pharmaceutical composition contains the N-glycan or the fraction thereof as an active ingredient. The N-glycan derived from honeycomb skin including Bombus ignitus larvae and pupae or from Bombus terrestris worker bees, and the fraction thereof are known to be biologically active, and thus are able to be used as ingredients for drugs, cosmetics, and functional foods and are valuable as pharmaceutical and functional molecules. In particular, the N-glycan and the fraction thereof are effective in preventing hemadostenosis, and ...

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Номер записи: 94

10-07-2017 дата публикации

GLYCOSAMINOGLYCAN DERIVED FROM BUMBUS IGNITUS QUEEN AND USES THEREOF FOR SUPPRESSING FAT ACCUMULATION

Номер: KR1020170080555A

Автор: AHN, MI YOUNG, HWANG, JAE SAM, YOON, HYUNG JOO, YUN, EUN YOUNG, KIM, SUN JA, KIM, BAN JI

Принадлежит:

Glycosaminoglycan derived from Bumbus ignitus queen suppresses abdominal fat accumulation and reduces cholesterol level and free fatty acids in serum on a high-fat diet. Additionally, glycosaminoglycan of the present invention prolongs activated partial thromboplastine time (APTT) in plasma, and thus prevents blood coagulation, and suppresses adhesive protein-related laminin present on microvascular endothelial cells. Also, glycosaminoglycan of the present invention suppresses protein damage in blood globulins and suppresses lipoperoxide accumulation (MDA level) in hepatocytes. Further, at the cellular level, glycosaminoglycan of the present invention produces nitric oxide (NO) in vascular endothelial cells and thus reduces vascular tension. Also, glycosaminoglycan of the present invention was found to prevent an increase of the blood pressure caused by a high-fat diet in the rats in one month treatment. Accordingly, glycosaminoglycan derived from Bumbus ignitus queen can provide compositions ...

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Номер записи: 95

20-11-2015 дата публикации

Transgenic silkworms producing antimicrobial peptide

Номер: KR0101570783B1

Автор: 구태원, 윤은영, 최광호, 김성렬, 박승원, 강석우, 김성완

Принадлежит: 대한민국

... 본 발명은 항균 펩타이드가 함유된 형질전환 누에 및 이를 이용하여 항균 펩타이드가 함유된 형질전환 누에를 대량 생산하는 방법에 관한 것으로, 보다 상세하게는 표지 유전자 조절 프로모터, 표지 유전자, 누에 유래 프로모터 및 누에 유래 BmRelish1t 유전자가 작동가능하게 연결된 유전자 컨스트럭트를 포함하는 재조합 발현벡터를 제작하여 상기 재조합 발현벡터로 누에를 형질전환시킴으로써 항균 펩타이드가 함유된 누에를 생산하는 형질전환 누에를 제조할 수 있으며, 이로 인해 천연항생제로서 개발이 가능하여, 가축사료 첨가제뿐만 아니라 화장품, 치약 등 생활용품의 소재 등으로 유용하게 사용될 수 있다.

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Номер записи: 96

08-05-2017 дата публикации

N-GLYCAN DERIVED FROM HONEYCOMB SKIN INCLUDING BOMBUS IGNITUS LARVAE AND PUPAE, N-GLYCAN DERIVED FROM BOMBUS TERRESTRIS WORKER BEES, AND USE THEREOF

Номер: KR1020170047538A

Автор: AHN, MI YOUNG, HWANG, JAE SAM, YOON, HYUNG JOO, YUN, EUN YOUNG, KIM, SUN JA

Принадлежит:

The present invention relates to: N-glycan derived from Bombus ignitus honeycomb skin having a sugar chain structure of (Hex)3(HexNAc)2(dHex) (m/z1079.4), and a fraction containing the same; N-glycan derived from Bombus ignitus honeycomb skin of (Hex)6, (Hex)7, (Hex)10, (Hex)11, (Hex)12, and N-glycan derived from Bombus terrestris worker bees of (Hex)3(HexNAc)2(dHex)1(m/z1080.4); and a pharmaceutical composition for preventing and treating hemadostenosis, wherein the pharmaceutical composition contains the N-glycan or the fraction thereof as an active ingredient. The N-glycan derived from honeycomb skin including Bombus ignitus larvae and pupae or from Bombus terrestris worker bees, and the fraction thereof are known to be biologically active, thereby being able to be used as ingredients for medicines, cosmetics, and functional foods and thus being worth as pharmaceutical and functional molecules. In particular, the N-glycan and the fraction thereof are effective in preventing hemadostenosis ...

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Номер записи: 97

12-05-2017 дата публикации

COMPOSITION FOR HDAC6 INHIBITORS FOR ENHANCEMENT OF BARRIER FUNCTION IN LARGE INTESTINE EPITHELIAL CELLS

Номер: KR101734072B1

Автор: HWANG, JAE SAM, YUN, EUN YOUNG, NAM, SUNG HEE, AHN, MI YOUNG, KIM, MI AE, KIM, SEONG HYUN, LEE, JOOM HA, KIM, IN WOO, KIM, HO, HONG JI, LU LI FANG, ZHANG PENG, KIM, DAE HONG, LEE, IK HWAN

Принадлежит: REPUBLIC OF KOREA(MANAGEMENT : RURAL DEVELOPMENT ADMINISTRATION), DAEJIN UNIVERSITY CENTER FOR EDUCATIONAL INDUSTRIAL COOPERATION

The present invention relates to a composition for HDAC6 inhibitors for the enhancement of a barrier function in large intestine epithelial cells. More specifically, the present invention relates to a composition for HDAC6 inhibitors which enhances a barrier function in large intestine epithelial cells by preventing a deacetylation of tubulin, and contains potassium acetate as an effective component. According to the present invention, the generation of microtubules can be promoted while securing low cytotoxicity; and the cytoskeleton of epithelial cells inside the large intestines is enhanced, thereby improving a barrier function. COPYRIGHT KIPO 2017 ...

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Номер записи: 98

12-02-2016 дата публикации

NOVEL LACTOFERRICIN-LIKE ANTIFUNGAL PEPTIDE AND COMPOSITION THEREOF

Номер: KR1020160014801A

Автор: HWANG, JAE SAM, YUN, EUN YOUNG, NAM, SUNG HEE, AHN, MI YOUNG, KIM, MI AE, LEE, JOON HA, KIM, IN WOO, KIM, SAGN HEE, LEE, DONG GUN, LEE, WON YOUNG, CHOI, HYE MIN

Принадлежит:

The present invention relates to a novel lactoferricin-like antifungal peptide and a composition thereof. The antifungal peptide of the present invention is represented by SEQ ID NO: 2, and is synthesized from an amino acid deducted from a gene of a peptide represented by SEQ ID NO: 1. According to the present invention, provided are a novel lactoferricin-like antifungal peptide separated from scolopendra subspinipes, which has remarkable antifungal activity without cytotoxicity, and a composition thereof. Therefore, according to the present invention, an antibiotic as an antifungal medicine safe to human body, a food preservative, a cosmetic preserving agent, a medicine, etc. can be provided. COPYRIGHT KIPO 2016 ...

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Номер записи: 99

11-10-2012 дата публикации

OIL SEPARATION STRUCTURE FOR A SCROLL TYPE COMPRESSOR

Номер: WO2012138101A3

Автор: YUN, Eun Young, CHOI, Yong Wan, JOO, Sang Hyun, BAE, Jae Hyun, SHIN, Jin Young, LEE, Jae Wook

Принадлежит:

The present invention relates to an oil separation structure for a scroll type compressor. In the oil separation structure, a receiving part is formed in a back surface of a fixed scroll including a circular end plate and a spiral element protruding from a front surface of the circular end plate, and an oil separator for separating oil from compressed refrigerant within the receiving part. Also, a rear housing is installed on a back surface of the fixed scroll, an opening is formed in one end of the receiving part, and a closed part is formed on the other end of the receiving part. Also, a refrigerant introduction hole is formed in one side of a sidewall of the receiving part.

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Номер записи: 100