METHODS, COMPOUNDS, COMPOSITIONS AND VEHICLES FOR DELIVERING 3-AMINO-1-PROPANESULFONIC ACID

19-06-2008 дата публикации

Номер:

US2008146642A1

Автор: KONG XIANQI, ATFANI MOHAMED, BACHAND BENOIT, BOUZIDE ABDERRAHIM, CIBLAT STEPHANE, LEVESQUE SOPHIE, MIGNEAULT DAVID, VALADE ISABELLE, WU XINFU, DELORME DANIEL

Принадлежит:

Контакты:

Номер заявки: 07-39-8716

Дата заявки: 12-10-2007

The invention relates to methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid (3APS) in a subject, preferably a human subject. The invention encompasses compounds that will yield or generate 3APS, either in vitro or in vivo. Preferred compounds include amino acid prodrugs of 3APS for use, including but not limited to, the prevention and treatment of Alzheimer's disease.

CPC - классификация

A A6 A61 A61K A61K3 A61K31 A61K31/A61K31/1 A61K31/14 A61K31/145 A61K31/18 A61K4 A61K47 A61K47/A61K47/5 A61K47/54 A61K47/542 A61K47/545 A61K47/549 A61K47/55 A61K47/554 A61K47/6 A61K47/64 A61P A61P2 A61P25 A61P25/A61P25/0 A61P25/00 A61P25/1 A61P25/16 A61P25/2 A61P25/28 A61P3 A61P3/A61P3/0 A61P3/00 A61P4 A61P43 A61P43/A61P43/0 A61P43/00 A61P9 A61P9/A61P9/0 A61P9/00 A61P9/1 A61P9/14 C C0 C07 C07C C07C3 C07C30 C07C309 C07C309/C07C309/1 C07C309/14 C07C309/15 C07C309/18 C07C309/19 C07C309/2 C07C309/24 C07D C07D2 C07D20 C07D207 C07D207/C07D207/1 C07D207/16 C07D209 C07D209/C07D209/2 C07D209/20 C07D21 C07D217 C07D217/C07D217/2 C07D217/24 C07D23 C07D233 C07D233/C07D233/6 C07D233/64 C07D28 C07D285 C07D285/C07D285/3 C07D285/36 C07D285/38 C07D29 C07D291 C07D291/C07D291/0 C07D291/02 C07D3 C07D31 C07D317 C07D317/C07D317/4 C07D317/40 C07D32 C07D323 C07D323/C07D323/0 C07D323/02 C07D33 C07D333 C07D333/C07D333/2 C07D333/24 C07H C07H1 C07H15 C07H15/C07H15/1 C07H15/12 C07H7 C07H7/C07H7/0 C07H7/02 C07J C07J9 C07J9/C07J9/0 C07J9/00 C07J9/005 C07K C07K5 C07K5/C07K5/0 C07K5/06 C07K5/060 C07K5/0602 C07K5/06026 C07K5/0605 C07K5/06052 C07K5/0606 C07K5/06069 C07K5/0608 C07K5/06086 C07K5/08 C07K5/080 C07K5/0806 C07K5/081 C1 C12 C12P C12P1 C12P11 C12P11/C12P11/0 C12P11/00 C12P13 C12P13/C12P13/0 C12P13/00 C12P13/001 Y Y0 Y02 Y02P Y02P2 Y02P20 Y02P20/Y02P20/5 Y02P20/55

IPC - классификация

A A6 A61 A61K A61K3 A61K31 A61K31/A61K31/1 A61K31/13 A61K31/18 A61K31/4 A61K31/41 A61K31/415 A61P A61P2 A61P25 A61P25/A61P25/0 A61P25/00 A61P3 A61P3/A61P3/0 A61P3/00 C C0 C07 C07C C07C2 C07C21 C07C211 C07C211/C07C211/0 C07C211/02 C07D C07D2 C07D20 C07D207 C07D207/C07D207/0 C07D207/04 C07D21 C07D217 C07D217/C07D217/0 C07D217/00 C07D23 C07D233 C07D233/C07D233/5 C07D233/54 C07D29 C07D291 C07D291/C07D291/0 C07D291/02 C07D295 C07D295/C07D295/0 C07D295/02 C07D3 C07D31 C07D315 C07D315/C07D315/0 C07D315/00 C07K C07K5 C07K5/C07K5/0 C07K5/08 C1 C12 C12P C12P1 C12P11 C12P11/C12P11/0 C12P11/00

Цитирование НПИ

Marnela et al., J. Neurochem., 1984, 43(6), p1650-1653.
Sawada et al., J. Pharm. Exp. Ther., 1999, 291, p705-709.