27-11-2014 дата публикации
Номер: US20140348719A1
Принадлежит:
In one aspect, the invention relates to filter apparatuses useful as sampling media and stabilizing pharmaceutical compounds, methods of making same, compositions useful for stabilizing pharmaceutical compounds, and methods of isolating pharmaceutical compounds from an air stream using the apparatuses and compositions. This abstract is intended to be used as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. 1. A filtration apparatus comprising:(a) a composition of an ionic liquid iodide and an antioxidant selected from ascorbic acid (Vitamin C), adipic acid, butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), citric acid, fumaric acid, glutamic acid, malic acid, propyl gallate, sulfurous acid, tartaric acid, tocopherol (Vitamin E), thiols, and derivatives and salts thereof; and(b) a hydrophilic filter membrane.2. The apparatus of claim 1 , wherein the ionic liquid iodine comprises at least one dialkylimidazolium iodide compound.3. The apparatus of claim 1 , wherein the ionic liquid iodine comprises methyl propylimidazolium iodide (MPII).4. The apparatus of claim 1 , wherein the antioxidant is ascorbic acid claim 1 , or a derivative or salt thereof.5. The apparatus of claim 1 , wherein the ascorbic acid claim 1 , derivative claim 1 , or salt thereof claim 1 , is selected from ascorbyl palmitate claim 1 , Mg ascorbyl phosphate claim 1 , ascorbyl acetate claim 1 , sodium ascorbate claim 1 , ascorbic acid palmitate and erythorbic acid.6. The apparatus of claim 1 , wherein the thiol claim 1 , derivative claim 1 , or salt thereof claim 1 , is select from thioglycerol claim 1 , cysteine claim 1 , acetylcysteine claim 1 , cystine claim 1 , dithioerythreitol claim 1 , dithiothreitol claim 1 , and gluthathione.7. The apparatus of claim 1 , wherein the sulfurous acid claim 1 , derivative claim 1 , or salt thereof claim 1 , is selected from sodium sulfate claim 1 , sodium bisulfite claim 1 , ...
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