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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 4162. Отображено 100.
02-02-2012 дата публикации

Medical Fluid Delivery System with RFID-Equipped Wand

Номер: US20120029349A1
Автор: Chad M. Gibson, Geoffrey S. Strobl, John K. Bruce
Принадлежит: Individual

An injection device ( 120 ) used in delivering medical fluids to a patient is provided. The injection device ( 120 ) may include a syringe plunger driver ( 126 a ) and a syringe ( 140 ). The syringe ( 140 ) may include a syringe data storage device ( 134 ). The injection device ( 120 ) may include a communication device ( 132 a ) disposable in each of attached and detached conditions. The communication device ( 132 a ) may be operable to read a data storage device ( 134 ) within its field of view. When the communication device ( 132 a ) is attached to the injection device ( 120 ) and the syringe ( 140 ) is installed on the injection device ( 120 ), the communication device ( 132 a ) may be operable to read the data storage device ( 134 ) associated with the syringe ( 140 ). When in a detached condition, the communication device ( 132 a ) may be operable to be hand manipulated such that various other data storage devices ( 134 ) may be read.

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Номер записи: 1
29-03-2012 дата публикации

Medical fluid injection system

Номер: US20120078091A1
Автор: Deborah Jean Brown, Todd Suchecki
Принадлежит: ACIST Medical Systems Inc

One implementation provides a method to provide injection procedure information in an injection system. In this implementation, the method includes displaying a plurality of different injection procedure options in a user interface of said system, wherein said plurality of different injection procedure options including a cardiac procedure option and a non-cardiac procedure option. The method further includes receiving a user selection of an injection procedure from said displayed plurality of difference injection procedure options, processing a default set of injection parameters based upon said selected injection procedure, and displaying said default set of injection parameters within the user interface of the system prior to an injection.

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Номер записи: 2
03-05-2012 дата публикации

Solid dose delivery device

Номер: US20120109046A1
Автор: Henrik Ljunggreen, Torben Strøm HANSEN
Принадлежит: Novo Nordisk AS

The invention relates to a medicament delivery device ( 1, 100 ) for delivering one or more solid dose pegs ( 10, 110 ) through the skin. The device ( 1, 100 ) has a number of exit openings ( 9, 109 ) corresponding to the number of solid dose pegs ( 10, 110 ) to be delivered. A detachable portion ( 3, 103 ) of the device ( 1, 100 ) is removed before use to uncover the exit openings ( 9, 109 ) and a release rod ( 17, 117 ). When the exit openings ( 9, 109 ) are pressed against the skin the release rod ( 17, 117 ) automatically disables a safety mechanism adapted to prevent unintended activation of the device ( 1, 100 ).

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Номер записи: 3
10-05-2012 дата публикации

Multi-lumen instrument for providing radiation to a body cavity

Номер: US20120116146A1
Автор: Carribeth B. Ramey, Rance A. Winkler, Timothy J. Patrick
Принадлежит: Cytyc Corp

A brachytherapy system for treating metastases on and around a patient's spinous process is provided. The device generally includes a catheter member having a proximal portion, a distal portion, and at least one lumen extending therethrough. The distal portion of the catheter member includes first and second branch members that are adapted to be positioned on opposed sides of a patient's spinous process. The device further includes first and second elongate anchoring elements disposed on the first and second branch members, and optionally can include at least one centering mechanism disposed within each of the first and second anchoring elements.

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Номер записи: 4
21-06-2012 дата публикации

Movable curved needle for delivering implants and methods of delivering implants

Номер: US20120158009A1
Автор: Isaac Ostrovsky, Jozef Slanda, Michael S.H. Chu
Принадлежит: Boston Scientific Scimed Inc

In one general aspect, a medical device can include a base having a guide and a handle. The medical device can also include a needle member that has a curved portion and a handle portion. The curved portion of the needle member can be configured to slidably move within the guide of the base from a first position to a second position different than the first position when the handle portion of the needle member is moved towards the handle of the base.

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Номер записи: 5
16-08-2012 дата публикации

Monitoring injector operation

Номер: US20120204997A1
Автор: Charles L. Winn, Mohd Touhid Khan, Todd M. Suchecki
Принадлежит: ACIST Medical Systems Inc

Embodiments of the present invention monitor resistance to the movement of the ram and detect one or more injector operation conditions based on that resistance. Some embodiments automatically detect whether a syringe is present in each syringe chamber of an injector based on ram movement resistance so that subsequent steps in the inject process can be automatically initiated or delayed based on the presence or absence of the syringe(s). Other injector operation conditions that can be detected include the injector's syringe sleeve being misaligned for operation, the syringe's wiper being misaligned within the syringe barrel, an occlusion within the syringe, overpressure during injection, and so on. A common way to measure resistance of the ram's movement is how much current is required by the motor driving the ram.

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Номер записи: 6
23-08-2012 дата публикации

Apparatus and method for effecting radiation treatment on a pre-selected anatomical portion of an animal body

Номер: US20120215052A1
Автор: Arie Luite Visscher, Johan Henning, Johann Kindlein, Wouter Peter Engels
Принадлежит: Nucletron Operations BV

A medical apparatus for effecting radiation treatment on a pre-selected anatomical portion of an animal body is disclosed. The medical apparatus may include a plurality of treatment channels configured to be positioned adjacent a body tissue and a plurality of delivery channels coupled to a corresponding number of treatment channels. The medical apparatus may also include a plurality of source channels configured to receive one or more energy sources, a tracking channel configured to receive a tracking element, and a connecting element configured to connect each delivery channel with either one of the plurality of sources channels or the tracking channel.

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Номер записи: 7
11-10-2012 дата публикации

Securing a Marker Wire

Номер: US20120259207A1
Автор: Maria Benson
Принадлежит: Hologic Inc

An apparatus for securing a marker wire relative to a lumen includes a hub to which the marker wire is secured. The hub includes a feature that secures the hub to an outer surface of the lumen. For example, the hub may include a base member secured to the marker wire and a separate fastener member which secures the hub to an outer surface of a lumen, where the base member includes a split tube segment that receives the lumen within an inner cylindrical opening. Alternatively, the hub may include a cylindrical slide lock collar member with a split tubular extension that receives the lumen within an inner cylindrical opening. Locking features may be included to help fix the two pieces of the hub in position relative to each other.

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Номер записи: 8
31-01-2013 дата публикации

Medical fluid injector device

Номер: US20130030290A1
Автор: Shigeru Nemoto
Принадлежит: Nemoto Kyorindo Co Ltd

A medical fluid injector device injecting a patient with a mixed medical fluid provided by a plurality of medical fluids and capable of simply setting injection conditions for the mixed medical fluid. A medical fluid injector ( 100 ) includes an injector head ( 110 ) injecting a diluted contrast medium into a patient and a controller unit ( 50 ). The controller unit ( 50 ) performs a process of receiving an input relating to an injection rate of the diluted medical fluid, a process of receiving an input relating to a mixture ratio by an operator, a process of calculating an injection rate of a contrast medium based on the mixture ratio, and a process of calculating an injection rate of physiological saline based on the mixture ratio. The injector head ( 110 ) injects the contrast medium and the physiological saline at the calculated injection rate of the contrast medium and the calculated injection rate of the physiological saline, respectively.

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Номер записи: 9
28-03-2013 дата публикации

Radiation catheter with multilayered balloon

Номер: US20130079580A1
Автор: Richard L. Quick
Принадлежит: SenoRx Inc

A catheter device for irradiating tissue surrounding a body site within a body of a patient, includes an elongated shaft which has a distal portion configured to be deployed within the body site. A treatment location at the distal portion has one or more radiation guides configured to receive a radiation source to irradiate tissue at least in part surrounding the body site. An inflatable multilayered balloon is located to surround the treatment location with a wall thereof having at least two layers including a first layer separate from, inside, and in contact with a second layer around an entire periphery of the first layer, and each of the first layer and the second layer being secured to the distal portion of the elongated shaft.

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Номер записи: 10
28-03-2013 дата публикации

ACTIVITY DELIVERY PROGRESS MONITOR

Номер: US20130079581A1
Автор: Agamaite James A., Descalzi Douglas, Griffith Scott R., Marsh Charles
Принадлежит:

A system and method for monitoring progress of a radiopharmaceutical injection procedure includes: measuring and monitoring radiopharmaceutical activity of a radiopharmaceutical remaining in at least a portion of a disposable administration set used with a radiopharmaceutical fluid delivery system; and displaying the radiopharmaceutical activity remaining in at least the portion of the disposable administration set to an operator. 1. A method for monitoring progress of a radiopharmaceutical injection procedure comprising:measuring and monitoring radiopharmaceutical activity of a radiopharmaceutical remaining in a portion of a disposable administration set used with a radiopharmaceutical fluid delivery device, wherein the measuring and monitoring are performed during the radiopharmaceutical injection procedure; anddisplaying the radiopharmaceutical activity remaining in the portion of the disposable administration set, wherein the displaying is performed during the radiopharmaceutical injection procedure.2. (canceled)3. (canceled)4. (canceled)5. (canceled)6. The method of claim 1 , wherein the measuring and monitoring is performed by one of an ionization chamber claim 1 , a CZT crystal detector claim 1 , a Geiger-Müller counter claim 1 , and a scintillating counter.7. The method of claim 1 , wherein displaying the radiopharmaceutical activity comprises:displaying a representation of the radiopharmaceutical activity remaining in the portion of the disposable administration set on a display device of the radiopharmaceutical fluid delivery device.8. (canceled)9. The method of claim 1 , wherein the measured radiopharmaceutical activity of the radiopharmaceutical remaining in the portion of the disposable administration set is the measured activity as a function of at least one of time claim 1 , flow rate claim 1 , and volume.10. (canceled)11. (canceled)12. The method of claim 1 , wherein the disposable administration set comprises:a medical fluid component;a ...

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Номер записи: 11
25-04-2013 дата публикации

REAL-TIME RADIATION TREATMENT PLANNING SYSTEM

Номер: US20130102831A1
Автор: BALTAS Dimos, KINDLEIN Johann, KUIPERS Frans, SAKAS Georgios, Schot Hans Martin
Принадлежит: Nucletron Operations B.V.

The invention relates to a real time radiation treatment planning system for use in effecting radiation therapy of a pre-selected anatomical portion of an animal body using hollow needles. According to embodiments of the invention, the system may include a processing means processing means-configured to perform a three-dimensional imaging algorithm and a three-dimensional image segmentation algorithm, with respect to one or more specific organs within the pre-selected anatomical portion and with respect to the needles, for converting the image data obtained with an imaging means into a three-dimensional image of the anatomical portion, using at least one single or multi-objective anatomy-based genetic optimization algorithm. For pre-planning or virtual simulation purposes, the processing means is arranged to determine in real time the optimal number and position of at least one of the needles, positions of energy emitting sources within the needles, and the dwell times of the energy emitting sources at the positions. For post-planning purposes, the processing means is arranged to determine, based on three-dimensional image information, in real time the real needle positions and the dwell times of the energy emitting sources for the positions. 132.-. (canceled)33. A radiation treatment planning system for use in effecting radiation therapy of a pre-selected anatomical portion of an animal body , comprising:an imaging device configured to generate image data corresponding to the anatomical portion;a positioning device configured to position the imaging device within the pre-selected anatomical portion, wherein the positioning device includes a template;a radiation delivery device configured to deliver at least one energy emitting source through at least one of a plurality of hollow needles inserted into the anatomical portion with the guidance of the template; convert the image data into a three-dimensional image of the anatomical portion;', 'designate multiple ...

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Номер записи: 12
02-05-2013 дата публикации

DISPENSER CARTRIDGE FOR RADIOPHARMACEUTICALS

Номер: US20130109907A1
Автор: BAPLUE Frederic, BEKAERT Philippe, Morelle Jean-Luc, Philippart Gauthier
Принадлежит: TRASIS S.A.

A cartridge for radiopharmaceutical packaging includes a low UV-absorbing plastic barrel, closed at one end by a cap and at the other by a piston. A shoulder cooperates with the barrel in a double-level snap-on system with a cavity cooperating with an injection fitting sleeve to make a seal. At a first end the cap has a peel-off porous liner covering the cavity. Radial fins protrude inside the cavity, for screwing the injection fitting and second radial fins protrude outside of the cap to fix to a cartridge protection shield. A second end minimizes a shadow area of UV flash lamp sterilization and ensures clearance for inserting an injection spike. The second end has a reduced wall thickness pierced by the spike during set up for dispensing of the pharmaceutical. An external cylindrical zone at the second end ensures leak tightness between the cap and the barrel. 19-. (canceled)10. An injection instrument configured to be reversibly snapped on the piston of a cartridge for the packaging of a pharmaceutical to form a temporary syringe plunger , the cartridge comprising a plastic barrel , closed at one end by a cap and at the other end by a piston; a shoulder cooperating with the barrel in a double-level snap-on system;', 'a cavity to cooperate with an elastomeric protection sleeve of injection means fitting, to make a seal, said cap being terminated at a first end by a peel-off porous liner covering said cavity;', 'a first plurality of radial fins protruding inside said cavity, for screwing the injection means fitting and with a second plurality of radial fins protruding on the outside of the cap to ensure fixation of the cap into a cartridge protection shield;', 'a second end opposite to the first end, shaped so to minimize a shadow area in the case of UV flash lamp sterilization and to ensure sufficient clearance for inserting a spike of the injection means, said second end having a reduced wall thickness for acting as a septum to be pierced by said spike at the ...

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Номер записи: 13
02-05-2013 дата публикации

Implant Cannula Having an Implant and a Method for Securing Implants in an Injection Cannula

Номер: US20130110077A1
Автор: Spilgies Heiko
Принадлежит: Acino AG

The application provides an injection cannula having an implant which is detachably secured in the cannula. The application also provides a method for detachably securing an implant in an injection cannula. 123-. (canceled)24. An injection cannula with an implant , wherein the implant is detachably secured in the injection cannula over at least part of at least one longitudinal side of the injection cannula with at least one physiologically tolerable material.25. The injection cannula of claim 24 , wherein the at least one physiologically tolerable material comprises one or more semi-solid materials or one or more cured materials.26. The injection cannula of claim 24 , wherein the at least one physiologically tolerable material comprises one or more semi-solid materials and one or more cured materials.27. The injection cannula of claim 25 , wherein the at least one physiologically tolerable material comprises a polymer material.28. The injection cannula of claim 26 , wherein the at least one physiologically tolerable material comprises a polymer material.29. The injection cannula of claim 24 , wherein the implant is detachably secured in the injection cannula over up to 50% of the surface area of the at least one longitudinal side.30. The injection cannula of claim 24 , wherein the implant is detachably secured in the injection cannula over at least one point on the surface of the at least one longitudinal side.31. The injection cannula of claim 24 , wherein the at least one physiologically tolerable material has a layer thickness of from 0.1 to 1.2 mm.32. The injection cannula of claim 24 , wherein the injection cannula has a lateral opening.33. The injection cannula of claim 32 , wherein the implant is arranged in a region of the lateral opening of the injection cannula.34. The injection cannula of claim 24 , wherein the implant comprises goserelin claim 24 , leuprorelin claim 24 , anastrolol claim 24 , risperidone or octreotide.35. The injection cannula of claim ...

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Номер записи: 14
02-05-2013 дата публикации

SYSTEMS AND METHODS FOR DELIVERING THERAPEUTIC AGENTS

Номер: US20130110080A1
Автор: Ducharme Richard W.
Принадлежит: Cook Medical Technologies LLC

The present embodiments provide systems and methods suitable for delivering a therapeutic agent to a target site. The systems generally comprise a container having first and second regions and a reservoir containing the therapeutic agent. A pressure source having pressurized fluid is in selective fluid communication with at least a portion of the reservoir. An outlet tube is in fluid communication with the reservoir of the container. At least one slot is formed in a lateral surface of the outlet tube at a position between first and second ends of the outlet tube. 1. A system suitable for delivering a therapeutic agent to a target site , the system comprising:a container for holding the therapeutic agent, wherein the container comprises first and second regions and has a reservoir containing the therapeutic agent;a pressure source having pressurized fluid, the pressure source in selective fluid communication with at least a portion of the reservoir of the container;an outlet tube in fluid communication with the reservoir of the container; andat least one slot formed in a lateral surface of the outlet tube at a position between first and second ends of the outlet tube.2. The system of claim 1 , where the first end of the outlet tube is disposed closer to a target site and the second end of the outlet tube is disposed proximal to the first end claim 1 , where the at least one slot is positioned closer to the first end than the second end of the outlet tube.3. The system of where the at least one slot extends between about 45 and about 270 degrees around a perimeter of the outer tube.4. The system of wherein fluid from the pressure source is directed through the first region of the container in a direction towards the second region of the container claim 1 , and wherein the fluid is at least partially redirected to urge the therapeutic agent in a direction from the second region of the container towards the first region of the container and subsequently towards the ...

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Номер записи: 15
16-05-2013 дата публикации

System and Method for Planning and Monitoring Multi-Dose Radiopharmaceutical Usage on Radiopharmaceutical Injectors

Номер: US20130123567A1
Автор: Agamaite James A., Descalzi Douglas, Griffith Scott R., Marsh Charles
Принадлежит:

A method for planning and monitoring radio pharmaceutical usage during a plurality of radio pharmaceutical injection procedures includes: providing a schedule of the plurality of radio pharmaceutical injection procedures to produce a planned patient schedule; based on the planned patient schedule, calculating a multi-dose container configuration for use during the plurality of radio pharmaceutical injection procedures; transferring the planned patient schedule to a radio pharmaceutical fluid delivery system; loading the multi-dose patient configuration into the radio pharmaceutical fluid delivery system; and conducting the plurality of radio pharmaceutical injection procedures based on the planned patient schedule. 1. A method of planning and monitoring radiopharmaceutical usage , the method comprising:receiving a patient schedule for a plurality of radiopharmaceutical injection procedures;based on the patient schedule, determining a multi-dose container configuration for use during the plurality of radiopharmaceutical injection procedures;transferring the patient schedule to a radiopharmaceutical fluid delivery system;providing the multi-dose container configuration to the radiopharmaceutical fluid delivery system; andconducting the plurality of radiopharmaceutical injection procedures based on the patient schedule.2. The method of claim 1 , wherein the patient schedule comprises claim 1 , for each of a plurality of patients claim 1 , a time of a radiopharmaceutical injection procedure for the patient and an activity removed from the multi-dose container of radiopharmaceutical for the patient.3. (canceled)4. The method of claim 1 , further comprising:editing the patient schedule after providing the multi-dose container configuration to accommodate one or more of the following: an additional patient, a cancelled patient, a time modification for a patient on the patient schedule, and a modification to an activity removed from the multi-dose container of configuration ...

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Номер записи: 16
16-05-2013 дата публикации

Hemodynamic pressure sensor test system and method

Номер: US20130123619A1
Автор: Leon T. Griggs
Принадлежит: ACIST Medical Systems Inc

A pressure sensor suitable for use in a powered contrast injector system may be tested to help validate the operability and/or integrity of the sensor. In some examples, the pressure sensor may be tested by generating a pressure pulse in a fluid line fluidly connected to the pressure sensor so as to generate a first pressure reading. A high pressure fluid at a pressure above a maximum operating pressure of the pressure sensor may be conveyed through a valve fluidly connected to the pressure sensor. Subsequent to conveying the high pressure fluid through the valve, the pressure sensor may again be tested by generating a pressure pulse in the fluid line fluidly connected to the pressure sensor so as to generate a second pressure reading. In some examples, the first pressure reading is compared to the second pressure reading to determine whether the pressure sensor has passed or failed.

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Номер записи: 17
16-05-2013 дата публикации

DRUG DELIVERY PUMP DRIVE USING LINEAR PIEZOELECTRIC MOTOR

Номер: US20130123749A1
Автор: DePolo Marco, Roe Steven, Wiegel Christopher
Принадлежит: ROCHE DIAGNOSTICS OPERATIONS, INC.

A drug delivery pump drive which uses a linear piezoelectric motor to advance a syringe piston to deliver a liquid drug and a method thereof are disclosed. The pump drive, provided in a drug delivery pump, provides silent operation and very low energy consumption compared to electric motor-based drives. The small size of the motor helps also to reduce overall size of the pump drive and the resulting drug delivery pump. 1. A drive system used to dispense a liquid drug from a drug container having a piston , said drive system comprising:a lead screw having a rotational axis and operably connected to the piston;a ratchet wheel provided along the rotational axis and operably connected to the lead screw to move the lead screw;a piezoelectric motor having a shaft, a nut engaging the shaft, and piezoelectric elements configured to produce reciprocating linear motion of the shaft relative to the nut adjacent the rotational axis, wherein the shaft of the piezoelectric motor is situated perpendicular to the rotational axis and is connected to a rocker; anda pawl operably connected to the shaft and engaging the ratchet wheel such that the reciprocating linear motion of the shaft is converted into unidirectional rotary motion of the ratcheted wheel about the rotational axis which moves the lead screw and advances the piston to dispense the liquid drug from the drug container.2. The drive system according to claim 1 , wherein the lead screw is fixed to the ratchet wheel and operably connected to the piston via a nut.3. The drive system according to claim 1 , wherein the lead screw is fixed to the ratchet wheel and operably connected to the piston via a nut claim 1 , the nut having a key portion mounted slidably in a keyway of the drive system such that the nut is able to translate relative to the lead screw but not rotate.4. The drive system according to claim 1 , wherein the ratchet wheel is mounted rotatably about the lead screw claim 1 , and the drive system further comprises ...

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Номер записи: 18
23-05-2013 дата публикации

DOSIMETRICALLY CUSTOMIZABLE BRACHYTHERAPY CARRIERS AND METHODS THEREOF IN THE TREATMENT OF TUMORS

Номер: US20130131434A1
Автор: Brachman David, McBride Heyoung, Nakaji Peter, Thomas Theresa, Youssef Emad
Принадлежит:

Brachytherapy radioisotope carrier systems and methodology for providing real-time customized brachytherapy treatment to subjects with tumors difficult to control using conventional radiation therapy techniques. The invention generally relates to devices, methods and kits for providing customized radionuclide treatments, to help cure, slow progression or regrowth, or ameliorate the symptoms associated with tumors. 1. A radionuclide carrier system comprising:a) one or more individual implantable carriers configured to hold radioactive seeds in a precise location relative to a treatment area to produce a dosimetrically customizable implant in real-time for an area to be treated and wherein the individual carriers are small enough to fit in or on the area to be treated;b) wherein the carriers are selected from one or more tile carriers and/or gore carriers.2. The radionuclide carrier system of comprising a preplanned dosimetry based on precise dimensions and properties of the carriers to optimize the therapeutic index for an affected area.3. The radionuclide carrier system of claim 1 , wherein precise dimensions and properties of the carriers utilize biocompatible materials of differing thicknesses below and/or above a radiation source to act as a spacer to achieve a desired radiation dose delivery and sparing of normal tissue.4. The radionuclide carrier system of claim 1 , wherein the carrier further comprises a layer of tantalum claim 1 , tungsten claim 1 , titanium claim 1 , gold claim 1 , silver claim 1 , or alloys of these or other high Z materials as a foil claim 1 , grid or strip claim 1 , internal to or on a surface of the carrier to facilitate sparing of normal tissue by diminishing the penetration of the radiation into adjacent normal tissues.5. The radionuclide carrier system of claim 1 , wherein the individual implantable radionuclide carriers are inserted into or onto a tumor claim 1 , a void remaining following a tumor resection claim 1 , or a tumor bed; ...

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Номер записи: 19
18-07-2013 дата публикации

System, Method, and Apparatus for Estimating Liquid Delivery

Номер: US20130184676A1
Автор: Baier Michael J., Bodwell Jesse T., Gray Larry B., Kamen Dean, Kerwin John M., van der Merwe Dirk A.
Принадлежит: DEKA Products Limited Partnership

A pump for administering an agent to a patient includes a housing, a motor, a gearbox, a sensor, and a controller. The motor may be coupled to housing. The gearbox is operatively connected to said motor. The sensor senses a rotation of said motor. The controller acts to control operation of said motor and monitor the quantity of said agent delivered to said patient. The pump also includes a pump assembly such that the pump is configured such that the pump assembly may be interchangeable from a syringe pump assembly and a peristaltic pump assembly. 12-. (canceled)3. A syringe pump for administering an agent to a patient , the syringe pump comprising:a housing;a lead screw; anda sliding block assembly, said sliding block assembly comprising a cam, a cam projection fixedly coupled to the cam, and a threaded portion capable of engaging and disengaging from said lead screw, said threaded portion configured to be actuated between engagement and disengagement on the lead screw via rotation of the cam and cam projection, wherein said sliding block assembly is positioned within said housing.4. The syringe pump of claim 3 , wherein the sliding block assembly comprises a slot with a straight expanse and an arcuate expanse.5. The syringe pump of claim 4 , wherein the cam is configured such that rotation of the cam causes the cam projection to move within the slot and wherein as the cam projection moves within the straight expanse of the slot claim 4 , the threaded portion is configured to be actuated between engagement and disengagement with the lead screw.6. The syringe pump of claim 5 , wherein the syringe pump further comprises a clamping means configured for clamping any of a range of plunger flange sizes.7. The syringe pump of claim 6 , wherein the cam projection is configured such that it does not enter the straight expanse of the slot until the largest of the range of plunger flange sizes has been released by the means configured for clamping any of a range of plunger ...

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Номер записи: 20
08-08-2013 дата публикации

METHOD AND APPARATUS FOR BRACHYTHERAPY FEATURING TRACKING VIA SHAPE-SENSING

Номер: US20130204072A1
Автор: Binnekamp Dirk, Gutierrez Luis Felipe, Verard Laurent
Принадлежит: KONINKLIJKE PHILIPS ELECTRONICS N.V.

A brachytherapy method and apparatus include implanting an applicator having at least one radiation source or seed receiving channel () into soft tissue adjacent a target region () to be irradiated. A high resolution planning image () of the target region including the applicator is generated, wherein the high resolution planning image is used for determining a three-dimensional treatment plan (). A position of the applicator is tracked relative to the target region () and the treatment plan (). Tracking the position includes measuring, via shape-sensing, a location and shape of the at least one radiation source or seed receiving channel (). 1. A brachytherapy method comprising:{'b': 62', '40, 'implanting an applicator having at least one radiation source or seed receiving channel () in soft tissue adjacent a target region () to be irradiated;'}{'b': 64', '66, 'generating a high resolution planning image () of the target region including the applicator, the high resolution planning image for use in determining a three-dimensional treatment plan (); and'}{'b': 40', '66', '62, 'tracking a position of the applicator relative to the target region () and the treatment plan (), wherein tracking the position includes measuring, via shape-sensing, a location and shape of the at least one radiation source or seed receiving channel ().'}2. The method of claim 1 , further comprising:{'b': 72', '40', '62', '66, 'at least one selected from the group consisting of (i) deploying at least one radiation source or seed () into the target region () via the at least one radiation source or seed channel () and (ii) retrieving the at least one radiation source or seed out of the target region via the at least one radiation source or seed channel, wherein the at least one radiation source or seed traverses the channel within the target region according to the treatment plan ().'}3804062. The method of claim 2 , wherein tracking the position includes at least one selected from the group ...

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Номер записи: 21
15-08-2013 дата публикации

Integrated device for orienting an object according to a given spatial orientation and method for manufacturing the same

Номер: US20130205761A1
Автор: Alexandre Girard, Geneviève Miron, Jean-Philippe Lucking-Bigue, Jean-Sébastien Plante, Patrick Chouinard, Sylvain Proulx
Принадлежит: SOCPRA Sciences et Genie SEC

There is disclosed an integrated device for orienting an object according to a given spatial orientation comprising a frame and a supporting member connected thereto and adapted for supporting a portion of the object. The integrated device comprises a plurality of fluid actuated devices integrally molded and joined together through a joining portion to form an integral unit for displacing the supporting member with respect to the frame. Each fluid actuated device is actuatable between a first position wherein the device has a first length and a second position wherein the device has a second length. The integrated device comprises an actuation mechanism for actuating each fluid actuated device between the first position and the second position to enable displacing the supporting member with respect to the frame, thereby orienting the object according to the given spatial orientation. The integrated device may be of particular interest in the medical sector as a medical object manipulator for reaching a given target in an anatomical structure. A manufacturing method is also provided.

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Номер записи: 22
15-08-2013 дата публикации

SYSTEM AND METHOD FOR MINIMALLY INVASIVE DISEASE THERAPY

Номер: US20130211179A1
Автор: Mark Joseph L., Nicoson Zachary R.
Принадлежит: SUROS SURGICAL SYSTEMS, INC.

A system for treating a lesion site of a patient is disclosed. The system includes a cannula having a lumen, a conduit in communication with said lumen, an introducer stylet removably disposed within said cannula, a resecting device selectively insertable within said cannula, and an adjuvant treatment device selectively insertable within said cannula.

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Номер записи: 23
29-08-2013 дата публикации

EXPANDABLE BRACHYTHERAPY DEVICE

Номер: US20130225902A1
Автор: BERGMAN Joshua J., Govil Amit Prakash, GRIFFITH NATHAN CHRISTOPHER, MILLAGE KYLE KEVIN, STEPHENS DAVID WESLEY, WHITE JACK C.
Принадлежит: THERAGENICS CORPORATION

A method for brachytherapy in a lumpectomy cavity of a breast including, positioning a distal end of a brachytherapy device within the cavity, expanding an expandable surface portion located between proximal and distal ends of the device within the cavity, the source lumen tubes defining a curved configuration within the cavity; and positioning a source of radiation sequentially within one or more source lumens of the source lumen tubes according to a brachytherapy treatment plan. The device includes an inner tube, and a plurality of source lumen tubes located around the inner tube and including distal ends secured together with the inner tube at the distal end disposed within the body cavity, the source lumen tubes comprising proximal portions sufficiently long to extend outside the breast. 112-. (canceled)13. A brachytherapy device for treating tissue surrounding a body cavity within a patient , comprising:a) an elongated shaft having a longitudinal axis and a distal shaft portion and having a plurality of tubular members that extend along the distal shaft portion, the distal shaft portion being configured to be deployed within the body cavity, the plurality of tubular members being configured to be radially off-set from the longitudinal axis at the distal shaft portion to facilitate asymmetric irradiation of the body cavity when the distal shaft portion is deployed within the body cavity; andb) an expandable member coupled to the elongated shaft to define an expandable volume around the distal shaft portion.1427-. (canceled)28. A brachytherapy device for facilitating asymmetrical irradiation of a body cavity , comprising:an elongated shaft having a proximal end, a distal end, and a distal shaft portion proximal to the distal end, the elongated shaft having a centrally located longitudinal axis; andan expandable member coupled to the elongated shaft to define an expandable volume at the distal shaft portion, a plurality of off-set radiation delivery lumens, each ...

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Номер записи: 24
29-08-2013 дата публикации

PIERCE AND FILL DEVICE

Номер: US20130225903A1
Автор: Dumont Philippe, Franci Xavier, Lindgaard Svein-Erik
Принадлежит: GE HEALTHCARE LIMITED

A pierce and fill connector cap for a vial sealed by an elastomeric septum includes a vial collar and a needle holder. The vial collar body defines a collar aperture to be positioned in overlying registry with the septum of the vial, and the needle holder includes a needle holder body providing a means for holding an elongate needle in registry with the collar aperture. The needle holder body being moveable with respect to said vial collar between a first position spaced from the vial collar and a second position proximate the vial collar, such that a needle held by the needle holder will puncture through the vial septum. 1. A connector cap for a vial sealed by an elastomeric septum , said connector cap comprising:a vial collar comprising a vial collar body defining a collar aperture to be positioned in overlying registry with the septum of the vial,a needle holder comprising a needle holder body providing a means for holding a an elongate needle in registry with the collar aperture, said needle holder body being moveable with respect to said vial collar between a first position spaced from said vial collar and a second position proximate said vial collar, such that a needle held by said needle holder will puncture through the vial septum.2. A connector cap of claim 1 , further comprising a piercing guide comprising an annular guide body fixed between said vial collar and said needle holder claim 1 , said guide body defining a guide cavity in fluid communication with said collar aperture.3. A connector cap of claim 2 , wherein said guide body is affixed to said vial collar.4. A connector cap of claim 3 , wherein said guide body is removably attached to said vial collar.5. A connector cap of claim 1 , wherein said vial collar is removably attachable to the vial.6. A connector cap of claim 1 , wherein said needle holder holds a first and second needle spaced from the septum when in the first position and wherein both said first and second needles extend through the ...

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Номер записи: 25
26-09-2013 дата публикации

Brachytherapy Seed, Methodology and Calculating Dose of Brachytherapy and Method of Treatment

Номер: US20130253255A1
Автор: Van Niekerk Wayne
Принадлежит: NORTHERN ONCOLOGY (PTY) LTD

The invention provides for a brachy-therapy seed, wherein the seed includes at least two disparate radionuclides of a chemical element, the radionuclides encapsulated to form a brachytherapy seed and wherein the combination of the disparate radionuclides of the chemical element is used to augment dosimetric parameters and radiobiological characteristics of the brachytherapy seed. The invention also provides a method of manufacturing a brachytherapy seed that includes the steps of bombarding elemental silver with high energy protons produced by a cyclotron to obtain a target of 100 Pd and 103 Pd; dissolving and passing the target through a column of resin beads; placing at least one resin bead having adsorbed 100 Pd and 103 Pd into a titanium tube that is closed at one end; inserting a radiopaque member into the titanium tube; and closing the opposite end of the titanium tube. 1. A brachytherapy seed , wherein the seed includes at least two disparate radionuclides of a chemical element , the radionuclides encapsulated to form a brachytherapy seed and wherein the combination of the disparate radionuclides of the chemical element is used to augment dosimetric parameters and radiobiological characteristics of the brachytherapy seed.2. A brachytherapy seed as claimed in claim 1 , wherein the disparate radionuclides have different half-lives claim 1 , which result in different energy and decay properties.3. A brachytherapy seed as claimed in any one of the preceding claims claim 1 , wherein the dosimetric parameters of the disparate radionuclides are different claim 1 , and the final dose distribution and radiobiological effectiveness of the resultant radiation being dependent on the combination of the dosimetric characteristics of the disparate radionuclides used in the brachytherapy seed.4. A brachytherapy seed as claimed in any one of the preceding claims claim 1 , wherein a ratio of the disparate radionuclides claim 1 , and therefore the dosimetry of the disparate ...

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Номер записи: 26
10-10-2013 дата публикации

APPARATUS, SYSTEMS AND METHODS FOR DELIVERY OF MEDICATION TO THE BRAIN TO TREAT NEUROLOGICAL CONDITIONS

Номер: US20130267928A1
Автор: Horlen Kyle, Imran Mir, Morgan Phillip, Spher Paul, Tranchina Ben
Принадлежит: Incube, LLC

Various embodiments provide an apparatus, system method for treating neurological conditions by delivering solid form medication to the ventricles or other areas of the brain. Particular embodiments provide an apparatus and method for treating epilepsy and other neurological conditions by delivering solid form medication to ventricles in the brain wherein the medication is contained in a diffusion chamber so as to allow the medication to dissolve in the cerebrospinal fluid of the brain and then diffuse out of the diffusion chamber to be delivered to the ventricles and brain tissue. In one or more embodiments, portions of apparatus have sufficient flexibility to conform to the shape of the ventricles of the brain when advanced into them and/or to not cause deformation of the ventricle sufficient to cause a significant physiologic effect. 1. An apparatus for delivery of medication to the ventricles within the brain of a patient , the apparatus comprising:a flexible delivery member having a proximal end, a distal end, and a lumen for advancement of a solid form medication element through the delivery member, the medication element comprising at least one drug, wherein the delivery member is configured to be advanced into a selected ventricle of the brain from a site outside the brain; anda diffusion chamber coupled to the distal end of the delivery member; the diffusion chamber having a wall and an interior volume for receiving the medication element and at least one diffusion section positioned in the wall allowing cerebrospinal fluid (CSF) to enter and exit the chamber; wherein the chamber is configured to i) retain a medication element received from the delivery member; ii) dissolve the medication element in fluid within the interior volume to form a drug solution; and iii) diffuse drug from the drug solution through the at least one diffusion section to CSF within the selected ventricle of the brain; andwherein the diffusion chamber and the delivery member have ...

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Номер записи: 27
17-10-2013 дата публикации

SOLID DRUG DELIVERY APPARATUS, FORMULATIONS AND METHODS OF USE

Номер: US20130273173A1
Автор: Imran Mir
Принадлежит: InCube Labs, LLC

Embodiments provide apparatus and methods for delivering solid form medications such as pellets to various locations in the body. One embodiment provides an apparatus for in vivo delivery of medication pellets comprising a housing including a port, a pellet-containing belt disposed in the housing, and a mechanism for transferring the pellets from the belt to a delivery site (DS) outside the housing. Each pellet contains a dose of drug to treat a medical condition. An elongate member is coupled to the housing and includes a lumen for pellet delivery, a proximal end coupled to the port and a distal end positioned at the DS. The pellet can be delivered to the DS at regular intervals or responsive to a detected biological event. Embodiments of the invention are particularly useful for delivering medication to treat a medical condition over an extended period without requiring a patient to take external medication. 1. An apparatus for in vivo delivery of solid form medication within the body of a patient , the apparatus comprising:a housing including a wall and a port in the wall; the housing configured to be implanted within the body of the patient;at least one belt disposed in the housing, the belt configured to carry a plurality of doses of solid form medication, each dose of medication disposed in a sealed packaging container and comprising at least one drug;an elongate member having a proximal and distal end and lumen, the proximal end coupled to the port in the housing wall and the lumen sized to receive the medication dose so that it may be advanced through the lumen to be delivered at the selected tissue site; anda mechanism for puncturing the packaging container and advancing the dose of the medication from the packaging container through the housing wall port and elongate member lumen to a tissue delivery site.2. The apparatus of claim 1 , wherein the mechanism includes an advancement member for puncturing the packaging container and advancing the medication ...

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Номер записи: 28
05-12-2013 дата публикации

SYRINGE TYPE PUMP

Номер: US20130324884A1
Автор: Hadváry Paul, Tschirky Hansjörg
Принадлежит:

In a syringe type pump with a barrel () and a piston () movable in the interior of the barrel the barrel has the shape of a segment of a toroidal tube () and the piston is moved by means of a driving rod () which is guided and supported by the inner surface of the barrel wall. By the toroidal shape the overall size of the pump is significantly reduced and by guiding and supporting the driving rod of the piston by the inner surface of the barrel wall intrinsic problems of tightness, stick-slip phenomena and blockage are solved. A device for injecting fluid into a patient's body or removing body fluid therefrom is using a syringe type pump with a toroidal barrel and a driving rod of the piston guided and supported by the inner surface of the barrel wall. 1. A syringe type pump comprising a barrel curved in a shape of a segment of a toroidal tube with a lengthwise extending axis , a connecting opening in a vicinity of one end of the barrel for the passage of fluid , a piston movable along the axis and tightly fitting in an interior of the barrel , and a driving rod for reciprocally moving the piston , the driving rod is guided and supported by an inner surface of a barrel wall.2. The pump according to wherein the driving rod is flexible.3. The pump according to wherein the barrel has a circular claim 1 , elliptical claim 1 , oval or angular cross-section.43. The pump according to to wherein the flexible driving rod is guided and supported by the inner surface of the barrel wall by means providing a low friction gliding contact.5. The pump according to wherein the driving rod is guided and supported by the inner surface of the barrel wall by means providing a rolling contact.6. The pump according to wherein control elements for the movement of the piston according to integrated or remote control signals.7. A device for injecting a fluid into a patient's body or retrieving body fluid therefrom a pump comprising a barrel curved in a shape of a segment of a toroidal tube ...

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Номер записи: 29
12-12-2013 дата публикации

RADIOPHARMACEUTICAL DELIVERY AND TUBE MANAGEMENT SYSTEM

Номер: US20130331635A1
Автор: Berry David H., Descalzi Douglas, Hoffman Raymond C., III Arthur E., Tucker Barry L., Uber, URAM MARTIN J.
Принадлежит: MEDRAD, INC.

A device for delivery of a radiopharmaceutical and, in some embodiments, delivery of a pharmaceutical agent are described herein. Various other components for delivery systems including tubing management systems, primer caps, diffusion chambers, radiation shields and syringe shields, and other devices and methods are also described. 1. A tubing management system comprising:a tubing channel;a shield plate covering the tubing channel;at least one pulley positioned to move forward and aft within the tubing channel;a spindle extending through the pulley;a handle disposed on an end of the spindle extending through the shield plate; anda slide contacting the spindle opposite the handle; anda track having an upper channel and a lower channel configured to accept the slide.2. The tubing management system of claim 1 , wherein the pulley further comprises a circumferential groove.3. The tubing management system of claim 2 , wherein the circumferential groove comprises a large side wall and a short side wall opposite the large side wall and wherein the short side wall faces the shield plate.4. The tubing management system of claim 1 , wherein the shield plate further comprises a pulley channel extending to an edge of the shield plate.5. The tubing management system of claim 4 , further comprising a secondary tubing channel extending from an edge of the shield plate to the pulley channel.6. The tubing management system of claim 5 , further comprising a retractor slot extending from the secondary tubing channel.7. The tubing management system of claim 5 , further comprising a pulley groove in cooperation with the pulley channel.8. The tubing management system of claim 1 , further comprising an upper shielded spacer and a lower shielded spacer operably connected to the shield plate.9. The tubing management system of claim 1 , wherein the system is configured and arranged to attach to an injector body.10. A primer cap comprising: a nut designed and configured to be grasped by a ...

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Номер записи: 30
12-12-2013 дата публикации

DELIVERY DEVICES AND METHODS FOR DELIVERING THERAPEUTIC AGENTS

Номер: US20130331777A1
Автор: Griffis Jack, Taylor W. Robert, Vito Raymond P., Wach Michael L.
Принадлежит:

Devices and methods for delivering therapeutic agents use an inverted member to deliver a therapeutic agent with little or no shear stress. The inverted member may have a movable continuous surface, the movable continuous surface having a first section and a second section opposing the first section, the second section surrounding an inner cavity that is configured to hold the therapeutic agent, the inverting member being configured to deliver the therapeutic agent by inverting at least a portion of the second section. 1. A delivery device for delivering a therapeutic agent , comprising:a housing; andan inverting member having a movable continuous surface, the movable continuous surface having a first section and a second section opposing the first section, the second section surrounding an inner cavity that is configured to hold the therapeutic agent, the inverting member being configured to deliver the therapeutic agent by moving at least a portion of the second section.2. The delivery device according to claim 1 , wherein the housing is concentrically arranged around the inverting member.3. The delivery device according to claim 1 , wherein the housing further includes a hollow cavity configured to house the inverting member.4. The delivery device according to claim 1 , wherein:the delivery device is configured to deliver the therapeutic agent at a distal end, the delivery device further comprising:the housing is a retractable sheath configured to move away from the distal end; andthe inverting member is configured to invert the portion of the second section when the retractable sheath is moved away from the distal end.5. The delivery device according to claim 4 , further comprising:a retaining rod, the retaining rod being configured to maintain a position of the inverting member when the retractable sheath is moved.6. The delivery device according to claim 1 , further comprising:a retractable sleeve disposed within the housing,wherein the retractable sleeve is ...

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Номер записи: 31
19-12-2013 дата публикации

APPARATUS FOR LOADING DOSIMETRICALLY CUSTOMIZABLE BRACHYTHERAPY CARRIERS

Номер: US20130338423A1
Автор: Brachman David, McBride Heyoung, Nakaji Peter, Thomas Theresa, Youssef Emad
Принадлежит:

A device for loading and customizing brachytherapy carriers based on the principles of optimizing a more precise and predictable dosimetry, and adaptable to the geometric challenges of a tumor bed in a real-time setting. The present invention relates to a specialized loading device designed to enable a medical team to create a radionuclide carrier for each patient and tumor reliably, reproducibly and efficiently. 1. A device for loading preformed brachytherapy carriers comprising:a base with a loading bed, a lid with a loading bed insert, one or more entry loading channels paired with an equal number of exit loading channels; and a loading channel support structure.2. The loading device of claim 1 , wherein the base comprises the one or more entry loading channels claim 1 , and a loading channel support structure; and the lid comprises the one or more exit loading channels.3. The loading device of claim 2 , wherein the number of entry and exit loading channel pairs is selected from 1 claim 2 , 2 claim 2 , 3 claim 2 , 4 or 5.4. The loading device of claim 3 , wherein the number of entry and exit loading channel pairs is 1 claim 3 , 2 or 3.5. The loading device of claim 1 , wherein the loader may include one or more bed liners of a specific size to fit within the loading bed claim 1 , and a specific width to raise a carrier to be loaded in relation to the exit and entry loading channels.6. The loading device of claim 5 , wherein the bed liners are 0.5 mm to 2.0 mm thick.7. The loading device of claim 5 , wherein the bed liners are 1 mm thick.8. The loading device of claim 2 , wherein a distal end of the lid is shorter than a distal end of the base; andwherein the distal end of the lid mates into the loading bed of the base with a loading bed tooth;wherein the tooth contains the one or more exit loading channels; and thus shortens the distance between the entry loading channel and the exit loading channel as compared to a full-length lid which ends adjacent to the ...

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Номер записи: 32
09-01-2014 дата публикации

Implant Delivery Catheter System And Methods For Its Use

Номер: US20140012189A1
Автор: Altman Peter A., Lovich Mark A., Miller Aaron J., Rosenman Daniel C., Schwartz Michael A.
Принадлежит: BioCardia, Inc.

Catheter systems and methods for implanting helical or dart-like implants into the myocardium or other body tissue. The catheter system includes a helix for fixing the distal end of the catheter to the myocardium, an implant held by the helix, mechanisms for driving the fixation helix into the myocardium, and mechanisms for driving the implant into the myocardium, removing the fixation helix and leaving the implant behind. The implant may be coated, filled, or made of a drug or drug eluting compound, or drug delivery matrix of any composition. 1. A catheter system for delivering a helical implant into tissue including:a helical implant;a steerable catheter; anda central holder disposed within the steerable catheter, said central holder releasably attached to the helical implant.2. The catheter system of wherein the central holder is releasably attached to the helical implant through a detent system.3. The catheter system of wherein the helical implant further comprises a plurality of detent receiving ports claim 1 , and the central holder further comprises a plurality of detents configured to engage the detent ports.4. The catheter system of claim 3 , wherein the detents of the central holder comprise outwardly biased fingers with inwardly facing detents which mate with the detent receiving ports.5. The catheter system of claim 4 , wherein the steerable catheter is longitudinally translatable relative to the central holder claim 4 , and operable to hold the detents of the outwardly biased fingers in engagement with the detent receiving ports when disposed about the detent fingers claim 4 , and operable to translate relative to the holder to allow the fingers to open to an unrestrained position to release the helical implant.6. The catheter system of wherein the helical implant is characterized by a proximal end and a distal end claim 4 , and the central holder is characterized by a proximal end and a distal end claim 4 , and the detent receiving ports are disposed ...

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Номер записи: 33
16-01-2014 дата публикации

SYSTEM AND METHOD FOR IMAGE-GUIDED THERAPY PLANNING AND PROCEDURE

Номер: US20140018607A1
Автор: Maier Cynthia
Принадлежит: Hologic, Inc.

A method for generating a treatment plan for therapy comprising obtaining image data representing a tissue, determining a therapy dose map comprising dose values for a plurality of dose points based on the image data, forming a desired dose value vector comprising the dose values for the plurality of dose points, determining a one or more potential therapy locations based on the image data, determining a therapy dose map equation for each of the plurality of dose points based on the one or more potential therapy locations, forming a matrix based on the therapy dose map equations for the each dose points, determining an inverse of the matrix and determining the treatment plan by multiplying the desired dose value vector by the inverse of the matrix. 121-. (canceled)22. A computer implemented method for generating a treatment approach for therapy , comprising:accessing, by a processor, a therapy dose map including a plurality of dose values for a plurality of target dose locations for target tissue;determining, by the processor, an output treatment plan for a patient from the therapy dose map, wherein the output treatment plan includes placement and any dwell time associated with one or more seeds;monitoring, by the processor, a treatment procedure implementing the output treatment plan, andmodifying, by the processor, the output treatment plan during execution of the treatment procedure.23. The method according to claim 22 , wherein monitoring includes at least one of:analyzing additional imaging of patient tissue, detecting changes or movement of tissue to be treated, detecting a deviation of catheter positioning, and detecting a deviation in positioning of critical structures.24. The method according to claim 22 , further comprising generating claim 22 , by the processor claim 22 , a treatment matrix with rows corresponding to a dose contribution of a plurality of potential dose locations.25. The method according to claim 23 , wherein determining the output ...

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Номер записи: 34
16-01-2014 дата публикации

DRUG DELIVERY TECHNOLOGY

Номер: US20140018725A1
Автор: Potter Charles, Watson John
Принадлежит: GLIDE PHARMACEUTICAL TECHNOLOGIES LIMITED

The present invention relates to novel drug delivery technology in the form of solid dose injection devices and methods which utilise a blade that is pushed into the skin to a predetermined depth before the before a solid drug formulation is pushed into the cut made by the blade. Thus the present invention also relates to delivering a therapeutic compound to a human or animal in the form of a solid dose injection comprising: providing an injection device comprising a casing; an actuation mechanism capable of ei generating a force, a blade, a solid drug formulation; and a means for pushing said solid drug formulation; wherein the blade is inser ted to a predetermined depth in the skin and, following insertion of the blade, the device is actuated such that the actuation mechanism capable of generating a force acts on the means for pushing to push the solid drug formulation out of the casing and into the human or animal body. 2. A solid dose injection device according to wherein the blade penetrates the skin to a predetermined depth of between 2 and 4 mm.3. A solid dose injection device according wherein the solid drug formulation is pushed into the body to a depth that extends beyond the depth of the blade.4. A solid dose injection device according to wherein the blade is substantially flat claim 1 , curved or hollow.5. A solid dose injection device according to wherein the blade makes a straight or arced cut in the skin.6. A solid dose injection device according to wherein the blade is a hollow needle.7. As solid dose injection device according to wherein the cut made by the needle is not a full circumference cut.8. A solid dose injection device according to wherein the solid drug is pushed through the lumen of the needle into the body.9. A solid dose injection device according to wherein the solid drug formulation comprises a cutting element to facilitate its passage through the skin.10. A solid dose injection device according to according to wherein the cutting ...

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Номер записи: 35
06-02-2014 дата публикации

Infusion Pump and Method For Improved Filling of a Fluidic System

Номер: US20140039392A1
Автор: Dogwiler Joerg, Geipel Andreas, Haueter Ulrich, Kuehni Florian, Schaltegger Reto, Scheurer Simon, Teutsch David, Zihlmann Rudolf
Принадлежит: ROCHE DIAGNOSTICS INTERNATIONAL AG

An infusion pump device and method for filling a fluidic system of the infusion pump with liquid medicament prior to infusion operation is presented. A control unit causes the infusion pump to: (a) bring a pump to an initial state; (b) switch a valve to a first state connecting a secondary reservoir to a first conduit and a primary reservoir; (c) retrieve medicament from the primary reservoir; (d) switch the valve to a second state connecting the secondary reservoir to a second downstream conduit; (e) expel the secondary reservoir contents into the second downstream conduit; (f) switch the valve to the first state; (g) retrieve the primary reservoir medicament; (h) switch the valve to the second state; and (i) expel the secondary reservoir contents into the second downstream conduit by shifting a piston to the initial position. 1. An infusion pump device comprising a primary reservoir for liquid medicament , a pump with a secondary reservoir to retrieve liquid medicament from the primary reservoir and to subsequently dose the liquid medicament from the secondary reservoir in incremental steps , a first upstream conduit fluidly connecting the primary reservoir with the pump , a second downstream conduit fluidly connected to the pump for transporting the liquid medicament to an infusion site interface , a valve for alternatingly connecting the pump to one of the conduits , and a control unit to control the operation of the infusion pump device , wherein for filling a fluidic system of the infusion pump device with liquid medicament prior to infusion operation , the control unit causes the infusion pump device to carry out the following steps:bringing the pump to an initial state where an inner volume of the secondary reservoir is minimal;{'sub': up', 'B', 'up', 'B, 'switching the valve to a first state, in which the secondary reservoir is connected to the first conduit and the primary reservoir and retrieving a volume of liquid medicament from the primary reservoir, ...

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Номер записи: 36
06-02-2014 дата публикации

Dosing Unit For An Infusion Pump Device

Номер: US20140039396A1
Автор: Andreas Geipel, David Teutsch, Florian Kuehni, Joerg Dogwiler, Reto Schaltegger, Rudolf Zihlmann, Simon Scheurer, Ulrich Haueter
Принадлежит: ROCHE DIAGNOSTICS INTERNATIONAL AG

A dosing unit for an ambulatory infusion pump device is presented. The dosing unit comprises a cylinder pump with a cylinder and a piston arranged in the cylinder. The piston has a shaft with a first threaded segment interacting with a threaded portion of the cylinder and can be displaced along a longitudinal axis of the cylinder by rotating the piston in regard to the cylinder around the axis. Furthermore, the piston allows for the relative or absolute determination of the longitudinal and/or rotational displacement of the piston in regard to the cylinder. In one embodiment, the piston shaft comprises a second segment provided with optically detectable markings that allow the monitoring of the longitudinal and/or rotational displacement of the piston in regard to the cylinder.

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Номер записи: 37
06-03-2014 дата публикации

BRACHYTHERAPY AND BUTTRESS ELEMENT CO-DELIVERY

Номер: US20140066688A1
Автор: Cassivi Stephen D.
Принадлежит: Mayo Foundation for Medical Education and Research

Brachytherapy delivery devices and buttress elements are described herein, along with methods of assembling the brachytherapy devices and the buttress elements for co-delivery of the brachytherapy delivery devices and buttress elements are described herein. 1. A brachytherapy delivery device , the brachytherapy delivery device comprising:a carrier line comprising a length extending between a first end and a second end, wherein radioactive material is distributed along the carrier line; anda stylet extending from a base to a tip, wherein the first end of the carrier line is attached to the stylet proximate the base of the stylet, and wherein the stylet is configured to be advanced tip-first through an opening and wherein further advancement of the stylet draws the carrier line through the opening.2. A device according to claim 1 , wherein the stylet comprises a bending stiffness greater than a bending stiffness of the carrier line.3. A device according to claim 1 , wherein the carrier line is configured to wrap around a right circular cylinder having a diameter of less than half of a length of the stylet between the base and the tip of the stylet.4. A device according to claim 1 , wherein the radioactive material comprises a plurality of radioactive seeds attached to the carrier line at discrete locations.5. A device according to claim 4 , wherein the plurality of radioactive seeds are adhesively attached to the carrier line.6. A device according to claim 4 , wherein the plurality of radioactive seeds are encased within the carrier line.7. A device according to claim 1 , wherein the carrier line is selected from the group consisting of: suture material claim 1 , ribbon claim 1 , wire claim 1 , and cable.8. A method of assembling a buttress element with radioactive material claim 1 , the method comprising: wherein the brachytherapy delivery device comprises a carrier line and a stylet, the carrier line comprising a length extending between a first end and a second end ...

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Номер записи: 38
27-03-2014 дата публикации

Fluid injection system having various systems for controlling an injection procedure

Номер: US20140088494A1
Автор: Arlie D. Long, III, Christopher M. Scutt, Jarrell T. Mcwilliams, John D. Shearer, Jr., Michael A. Spohn, Richard C. Morton, Walter J. Grumski
Принадлежит: Bayer Medical Care Inc

A fluid injection system that includes an injector head having a syringe for delivering a fluid to a patient; a mounting structure pivotally connected to the injector head and configured to support the injector head above a surface; and a control system operationally coupled to the injector head for controlling an injection procedure is disclosed. The fluid injection system is provided with various sensors to control various aspects of the fluid injection system, such as the establishment of a reference plane, the determination of a tilt angle of the injector head, and the determination of a temperature of an actuation system of the injector head.

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Номер записи: 39
27-03-2014 дата публикации

Multi-Dose Medical Fluid Injection System Having Patient-Specific Tubing Set with Use Indicator

Номер: US20140088559A1
Автор: Fago Frank M.
Принадлежит: Mallinckrodt LLC

A single-use, single-patient, or patient-specific tubing set () is disclosed. The tubing set () includes at least one check valve (), along with a use indicator (). This use indicator () provides a visual indication when the tubing set () has been used for an injection. In this regard, a piston () moves from one position to another when exposed to a certain fluid pressure. 1. A method of using a medical fluid injection system , the method comprising:executing a first interconnecting step comprising interconnecting a first patient-specific tubing set with a multi-patient tubing set, wherein said first patient-specific tubing set comprises a first use indicator;executing a first directing step comprising directing a medical fluid from said injection device through said multi-patient tubing set, and then through said first patient-specific tubing set;executing a first blocking step comprising blocking a backflow through said first patient-specific tubing set and into said multi-patient tubing step; andexecuting a first inducing step comprising inducing a single response by said first use indicator to said first directing step, wherein said single response is a physical change of said first use indicator.2. The method of claim 1 , wherein said first inducing step comprises moving a first indicator element from a first position to a second position.3. The method of claim 2 , further comprising retaining said first indicator element in said second position after said moving said first indicator element step.4. The method of claim 2 , wherein said moving said first indicator element step is initiated without deforming said first indicator element.5. The method of claim 2 , wherein said moving said first indicator element step comprises moving said first indicator element into a visibly observable position.6. The method of claim 2 , wherein said moving said first indicator element step comprises moving said first indicator element into an open space.7. The method of claim 1 ...

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Номер записи: 40
03-04-2014 дата публикации

INFUSION PUMP SYSTEM, AN INFUSION PUMP UNIT AND AN INFUSION PUMP

Номер: US20140094753A1
Автор: MERNOE MORTEN
Принадлежит: Asante Solutions, Inc.

An infusion pump unit includes a housing sized to allow the pump unit to be carried as a portable unit. The housing contains a controllable pumping system for pumping fluid. The pump actuator is lighter, smaller, quieter and less power consuming. 1. (canceled)2. A portable infusion pump device for dispensing insulin to a user , comprising:a portable pump housing defining a space to receive insulin;a user interface positioned on the portable pump housing, the user interface comprising a display device for showing data related to insulin treatment;a piston rod defining an exterior thread pattern and linearly movable in an axial direction in the housing to advance from a first position to a second position so as to dispense insulin from the pump housing when insulin is received in the pump housing;a ratchet mechanism to urge the piston rod from the first position to the second position;a gear that is rotatable in an activation direction to drive the piston rod from the first position to the second position, wherein the ratchet mechanism comprises a ratchet body that engages the gear, the ratchet body being adjustable from a non-activating position to an activating position so as to incrementally rotate the gear in the activation direction, and wherein the ratchet body maintains physical contact with the gear when moving between the non-activating position and the activating position; anda spring device that provides a drive force to the ratchet mechanism to advance the piston rod to the second position and thereby dispense insulin from the pump housing by mechanical power of the spring device when insulin is received in the pump housing.3. The portable infusion pump device of claim 2 , wherein the ratchet mechanism further comprises a pawl device that engages the gear to prevent rotation of the gear in a direction opposite the activation direction.4. The portable infusion pump device of claim 2 , wherein the spring device urges the ratchet body from the non-activating ...

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Номер записи: 41
03-04-2014 дата публикации

TELESCOPING PISTON DRIVE FOR MEDICAL INFUSION DEVICE

Номер: US20140094754A1
Автор: Servansky Daniel
Принадлежит: Animas Corporation

Described is a drive mechanism for a drug infusion pump. In one embodiment, an in-line drive mechanism is provided that includes a motor operatively coupled to a lead screw, which is configured to engage a piston. The piston includes a cavity to receive the motor and the lead screw such that the lead screw and at least a portion of the motor are substantially contained within the piston cavity when the piston is in a retracted position. In one embodiment, the motor rotates a drive shaft is configured to turn a mechanism comprising a piston, a lead screw, and a housing that cooperate to extend telescopically to drive a plunger into a medicament cartridge, thereby expelling fluid. 1. A medicament infusion device , comprising:a housing having an interior surface, the interior surface of the housing being at least partially threaded;a cavity within the housing configured to receive a cartridge, the cartridge having a reservoir for holding a medicament, a plunger for expelling the medicament from the reservoir, and an outlet port at a distal end of the housing;a drive mechanism disposed at a proximal end of the housing;a drive shaft in cooperation with the drive mechanism;a compound lead screw, the compound lead screw being essentially cylindrical and having at least a portion having a first diameter and at least a portion having a second diameter, wherein each of the portion having the first diameter and the portion having the second diameter are threaded, and the second diameter is greater than the first diameter;a piston having at least one threaded surface; andat least one keyway, whereinthe at least one keyway is configured to permit lateral motion of one of the compound lead screw or piston without permitting rotational motion.2. The medicament infusion device of wherein the at least partially threaded internal surface of the housing engages the threaded second diameter of the compound lead screw and the threaded surface of the piston engages the threaded portion ...

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Номер записи: 42
10-04-2014 дата публикации

INFUSION DEVICE WITH A GROOVED PISTON CHANNEL WALL

Номер: US20140100527A1
Автор: Gray John
Принадлежит: Medtronic Minimed, Inc.

An apparatus for delivering a fluid includes a housing, an inlet in the housing for receiving the fluid, and an outlet in the housing for discharging the fluid. A piston channel is provided within the housing through which the fluid flows from the inlet to the outlet. An actuator is positioned within the housing and is moveable between a retracted position and a forward position, the actuator defining a piston chamber for storing fluid received through the inlet when the actuator is in the retracted position and for driving the fluid stored in the piston chamber toward the outlet when the actuator transitions from the retracted position to the forward position. The actuator includes an armature and a piston coupled to the armature and moveable within the piston channel. The piston channel wall is provided with a groove for conducting fluid from the inlet to the outlet. 1. An apparatus for delivering a fluid , the apparatus comprising:a housing;an inlet in the housing for receiving the fluid;an outlet in the housing for discharging the fluid;a piston channel within the housing through which the fluid flows from the inlet to the outlet, the piston channel having a piston channel wall with at least one groove provided therein; and an armature; and', 'a piston coupled to the armature and moveable within the piston channel, the piston having an outer surface, wherein the at least one groove of the piston channel wall facilitates fluid flow from the inlet to the outlet., 'an actuator positioned within the housing and moveable between a retracted position and a forward position, the actuator defining a piston chamber for storing fluid received through the inlet when the actuator is in the retracted position, the actuator driving the fluid stored in the piston chamber toward the outlet when the actuator transitions from the retracted position to the forward position, the actuator comprising2. The apparatus of claim 1 , wherein the at least one groove comprises a helical ...

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Номер записи: 43
07-01-2016 дата публикации

INSTRUMENT LOCALIZATION IN GUIDED HIGH DOSE RATE BRACHYTHERAPY

Номер: US20160000519A1
Автор: DEHGHAN MARVAST EHSAN
Принадлежит:

A system for localizing one or more medical instruments includes a guidance grid () disposed in an operative relationship with a Workstation subject for receiving the one or more medical instruments () when deployed. An ultrasound imaging system () is configured to image a volume where the one or more medical instruments are deployed. A program module () is configured to register positions of the one or more medical instruments, using tracked position information and grid information, to the volume such that the positions of the one or more medical instruments can be visually monitored during a procedure. 1. A system for localizing one or more medical instruments. comprising:a guidance grid disposed in an operative relationship with a subject for receiving the one or more medical instruments when deployed;an ultrasound imaging system configured to image a volume where the one or more medical instruments are deployed; anda program module configured to register positions of the one or more medical instruments, using tracked position information and grid information to the volume, using image data, such that the positions of the one or more medical instruments are visually monitored during a procedure.2. The system as recited in claim 1 , wherein the one or more medical instruments are tracked using one of an electromagnetic tracking system and an optical shape sensing system.3. The system as recited in claim 1 , wherein the guidance grid is calibrated claim 1 , a priori claim 1 , to the imaging system.4. The system as recited in claim 1 , wherein the ultrasound imaging system includes a probe that is not tracked.5. The system as recited in claim 4 , wherein the probe includes a transrectal probe ultrasonic (TRUS) probe.6. The system as recited in claim 1 , wherein the one or more medical instruments include catheters claim 1 , which appear in the volume as bright regions such that the bright regions are employed to register the positions determined by a tracking ...

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Номер записи: 44
04-01-2018 дата публикации

DRUG DELIVERY DEVICE AND METHODS HAVING A RETAINING MEMBER

Номер: US20180001072A1
Автор: Belton Antonio, Clay Danielle L., Corrigan Sean, Grider Keith, Lau Michael Honsing, Leatzow Derek, Merves Michael, Snyder Lloyd, Soucia Jeffrey A.
Принадлежит: Warsaw Orthopedic, Inc.

Various embodiments of a device, a kit and method for delivering a drug depot are disclosed. The device comprises a housing including a lower body, an upper body, a ring member; and a drug cartridge. The lower body defines a lower body channel. The upper body defines an upper body channel. The drug cartridge defines a depot channel. The ring member is disposed extending upward from an annular step surface of the lower body toward a housing upper end. The ring member includes indicia indicating a characteristic of one or more drug depots in the drug cartridge. A plunger has a push rod for expelling the drug depot through the cannula to a site in the patient. A kit comprises the above components. A method includes assembling the components including selecting a ring member having indicia corresponding to one or more drug depots in the drug cartridge. 120-. (canceled)21. A drug delivery device comprising:a housing comprising a cavity; anda drug cartridge removably positioned in the cavity, the drug cartridge comprising a first plate having a channel with a drug pellet positioned therein, the drug cartridge comprising a second plate that is coupled to the first plate, the second plate comprising a first end including a first cantilever arm and an opposite second end including a cantilever arm, the cantilever arms being configured to effect an elastic occlusion of the channel.22. A drug delivery device as recited in claim 21 , wherein a force is required to deflect the cantilever arms so as to permit passage of the drug pellet through the channel.23. A drug delivery device as recited in claim 21 , wherein the cantilever arms are each configured to occlude the channel at an occluding position such that the drug pellet cannot pass through the channel at the occluding positions without force claim 21 , greater than that of gravity claim 21 , applied to the drug pellet sufficient to deflect one of the cantilever arms an amount permitting passage of the drug pellet past one ...

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Номер записи: 45
03-01-2019 дата публикации

Pulse infusion device system and method

Номер: US20190001056A1
Автор: Ofer Shay
Принадлежит: Medical Flow Systems Ltd

Aspects of the invention are related to a method and a system for administrating an infusion liquid pulse. The system includes a tubing system having an inlet connected to an external reservoir adapted to contain infusion fluids and an outlet connected to a catheter. The tubing system includes a check valve proximate to the inlet and an anti-siphon valve proximate to the outlet. The system further includes an automatic pulse flow generation device. The automatic pulse flow generation device includes an internal reservoir and a bidirectional pump configured to pump infusion fluid from the external reservoir to the internal reservoir and further pump an infusion fluid pulse from the internal reservoir to be injected by the catheter, the infusion liquid pulse has a volume of at least 2 ml and a velocity of at least 5 ml/min.

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Номер записи: 46
03-01-2019 дата публикации

KIT FOR AND METHOD OF ASSEMBLING AN APPLICATOR FOR INSERTING AN IMPLANT

Номер: US20190001110A1
Автор: BEELEN Dennis Cornelis Franciscus, MOORMANN Robertus Theodoor Maria, TAK Maurice Petrus Wilhelmus, VAN HARMELEN Martin
Принадлежит:

The invention pertains to a kit for assembling a disposable applicator for inserting an implant, in particular a rod-like implant containing an active substance, under the skin of a human or animal, the kit comprising a first component, in turn comprising a main housing part providing a handle for grasping and maneuvering the applicator, a cannula, and a cannula holder mounted in the main housing part, the main housing part having an opening which allows introduction of an implant into the proximal end of the cannula or the cannula holder, and, a second component for closing said opening, in turn comprising a second housing part and a rod attached to or forming an integral whole with the second housing part and mountable inside the cannula or the cannula holder. 120-. (canceled)21. A method of assembling a disposable applicator comprising:providing a first component comprising a main housing part, a cannula, and a cannula holder, wherein the main housing part provides a handle for grasping and maneuvering the applicator, wherein the cannula holder being slideably mounted in the main housing part, the main housing part having an opening which allows introduction of an implant into a proximal end of the cannula or the cannula holder;providing a second component for closing said opening, the second component comprises a second housing part and a rod, wherein the second housing part is at least partially complementary in shape to the main housing part and the rod being attached to or forming an integral whole with the second housing part;introducing an implant through the opening and into the proximal end of the cannula or the cannula holder; andmounting the rod inside the cannula or the cannula holder and closing the opening by attaching the main housing part to the second housing part.22. The method according to claim 21 , wherein the implant is taken from a reel and cut to size prior to introducing the implant into the proximal end of the cannula or the cannula ...

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Номер записи: 47
03-01-2019 дата публикации

KIT FOR AND METHOD OF ASSEMBLING AN APPLICATOR FOR INSERTING AN IMPLANT

Номер: US20190001111A1
Автор: BEELEN Dennis Cornelis Franciscus, MOORMANN Robertus Theodoor Maria, TAK Maurice Petrus Wilhelmus, VAN HARMELEN Martin
Принадлежит:

The invention pertains to a kit for assembling a disposable applicator for inserting an implant, in particular a rod-like implant containing an active substance, under the skin of a human or animal, the kit comprising a first component, in turn comprising a main housing part providing a handle for grasping and maneuvering the applicator, a cannula, and a cannula holder mounted in the main housing part, the main housing part having an opening which allows introduction of an implant into the proximal end of the cannula or the cannula holder, and, a second component for closing said opening, in turn comprising a second housing part and a rod attached to or forming an integral whole with the second housing part and mountable inside the cannula or the cannula holder. 1. Kit for assembling a disposable applicator for inserting an implant under the skin of a human or animal , the kit comprising:a first component, in turn comprising a main housing part providing a handle for grasping and maneuvering the applicator, a cannula, and a cannula holder slideably mounted in the main housing part, the main housing part having an opening which allows introduction of an implant into a proximal end of the cannula or the cannula holder, anda second component for closing said opening, in turn comprising a second housing part at least partially complementary in shape to the main housing part and attachable thereto to form a housing, and a rod attached to or forming an integral whole with the second housing part and mountable inside the cannula or the cannula holder.2. Kit according to claim 1 , wherein the first and second components are provided with complementary-features for irreversibly attaching one housing part to the other.3. Kit according to claim 1 , wherein the distance between the opening and the proximal end of the lumen of the cannula or the cannula holder is less than 20 mm.4. Kit according to claim 1 , wherein the proximal end of the lumen of the cannula or the cannula ...

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Номер записи: 48
13-01-2022 дата публикации

SINGLE-USE CASSETTE ASSEMBLY

Номер: US20220008704A1
Автор: Coyne Joshua, Grant David, LAUNOIS Pascal, RYAN Owen
Принадлежит: Enesi Pharma Limited

The invention relates to a single-use cassette assembly for use in a reusable solid dose formulation delivery actuator device. Such improvements permit delivery of at least one therapeutic or prophylactic compound, or a solid dose formulation including, for example, a vaccine comprising the same with improved safety and reliability. The invention further concerns an improved needle-free method for delivering at least one therapeutic compound or a formulation comprising the same. 1. A single use cassette assembly for use with a parenteral delivery actuator and configured to allow operative connection therewith , the cassette assembly comprising:a re-use prevention mechanism including at least:a cassette with one or more lockout clips having a first configuration, which permits use of the cassette with the actuator and a second configuration, which prevents re-use with the actuator and prevents reinsertion of the cassette into the actuator to an extent possible to enable actuation.2. The single use cassette assembly of wherein the first configuration is a non-extended state and the second configuration is a naturally biased extended state.3. The single use cassette assembly of ; wherein the re-use prevention mechanism comprises at least one lock-out clip.4. The single use cassette assembly of claim 1 , wherein the cassette assembly further comprises a cassette body for engaging the actuator device and a carriage housed within the cassette body claim 1 , the carriage having a channel configured to releasably retain a solid dose formulation.5. The single use cassette assembly of claim 4 , wherein each lockout clip has a first end clamped to the cassette body and a second end comprising a hook claim 4 , and wherein the cassette body comprises a hook retaining edge for engaging the hook in the second configuration.6. (canceled)7. The single use cassette assembly of wherein the carriage and cassette body comprise aligned apertures in which the lockout clips sit.8. The ...

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Номер записи: 49
11-01-2018 дата публикации

METHOD AND APPARATUS FOR DETERMINING THE POSITION OF A SURGICAL TOOL RELATIVE TO A TARGET VOLUME INSIDE AN ANIMAL BODY

Номер: US20180008163A1
Автор: Henning Johan, KINDLEIN Johann, KWA Stefan, SCHUURMAN Jeroen, VAN DER LUGT Wilco
Принадлежит:

The invention relates to a method for determining the position of a surgical tool relative to a target volume inside an animal body according to a pre-plan comprising the steps of i) obtaining a plurality of two-dimensional images of said target volume using imaging means, each 2D-image being represented by an image data slice I(x,y,z); ii) reconstructing from said plurality of image data slices I(x,y,z) a three-dimensional image of said target volume using transformation means, said 3D-image being represented by a volumetric image data array V(x,y,z); iii) displaying said three-dimensional image of said target volume to an user using displaying means. 115.-. (canceled)16. A surgical imaging method for determining and displaying , within a computer-generated display of a display device , a current position of a surgical tool relative to a planned position of the surgical tool within a patient , the surgical imaging method comprising:obtaining, via an imaging device, a three-dimensional image of a target volume within the patient;generating a first display signal causing the display device to display the three-dimensional image of the target volume on the display device, wherein the displayed three-dimensional image includes a three-dimensional representation of the surgical tool inserted in the target volume at a position corresponding to at least one planned position of the surgical tool;receiving a user selection, based on user interaction with the three-dimensional image on the display device, that identifies a selected location in the displayed three-dimensional image;generating, responsive to receiving the user selection that identifies the selected location in the displayed three-dimensional image, a control signal causing the imaging device to capture a corresponding location on the patient that corresponds to the selected location in the displayed three-dimensional image;obtaining, via the imaging device, a two-dimensional image of the corresponding location ...

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Номер записи: 50
09-01-2020 дата публикации

MONOCHROMATIC X-RAY IMAGING SYSTEMS AND METHODS

Номер: US20200009402A1
Автор: Silver Eric H.
Принадлежит: Imagine Scientific, Inc.

According to some aspects, a carrier configured for use with a broadband x-ray source comprising an electron source and a primary target arranged to receive electrons from the electron source to produce broadband x-ray radiation in response to electrons impinging on the primary target is provided. The carrier comprising a housing configured to be removeably coupled to the broadband x-ray source and configured to accommodate a secondary target capable of producing monochromatic x-ray radiation in response to incident broadband x-ray radiation, the housing comprising a transmissive portion configured to allow broadband x-ray radiation to be transmitted to the secondary target when present, and a blocking portion configured to absorb broadband x-ray radiation. 1. A monochromatic x-ray device comprising:an electron source configured to emit electrons;a primary target configured to produce broadband x-ray radiation in response to incident electrons from the electron source;a secondary target configured to generate monochromatic x-ray radiation via fluorescence in response to incident broadband x-ray radiation; anda housing for the secondary target comprising an aperture through which monochromatic x-ray radiation from the secondary target is emitted, the housing configured to position the secondary target so that at least some of the broadband x-ray radiation emitted by the primary target is incident on the secondary target so that, when the monochromatic x-ray device is operated, monochromatic x-ray radiation is emitted via the aperture having a monochromaticity of greater than or equal to 0.7 across a field of view of at least approximately 15 degrees.2. The monochromatic x-ray device of claim 1 , wherein claim 1 , when the device is operated claim 1 , monochromatic x-ray radiation is emitted via the aperture having a monochromaticity of greater than or equal to 0.8 across a field of view of at least approximately 15 degrees.3. The monochromatic x-ray device of claim 1 ...

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Номер записи: 51
09-01-2020 дата публикации

POSITIONING ASSISTANCE DEVICE FOR FOCAL RADIATION THERAPY

Номер: US20200009403A1
Автор: HAUTVAST GUILLAUME LEOPOLD THEODORUS FREDERIK, ISOLA Alfonso Agatino
Принадлежит:

An efficient direct parameter optimization (DPO) approach is provided, in which a dosimetry gradient-based iterative greedy technique is applied to determine positioning assistance information for catheter insertion in focal radiation therapy, by toggling between optimization of candidate catheter positions and candidate radiation source dwelling times. In the specific case of free hand delivered catheters, the insertion point may be directly selected by the human expert. Using monitoring of the catheter position by additional imaging modalities such as magnetic resonance imaging or ultrasound imaging, the method enables real-time orientation guidance and adaptive dose correction in the course of treatment delivery. 1. A positioning assistance device for assisting in positioning of catheters in a focal radiation therapy with respect to a pre-determined target volume and a given catheter insertion point , the positioning assistance device comprising:a candidate catheter providing unit, which is configured to provide candidate catheter data associated with the given catheter insertion point and defining candidate catheters by a respective candidate inserted-catheter position, respective candidate dwelling positions of radiation sources inside a given candidate catheter, and respective associated candidate dwelling times; ascertain and provide a gradient with respect to dwelling time of a composite constraint function for each current candidate catheter, using the current candidate dwelling times at associated current candidate dwelling positions of the candidate catheter, the composite constraint function combining at least two linear constraints representing clinical objectives with respect to radiation dose governing the focal radiation therapy; and to', 'pre-select a predetermined number of one or more candidate catheters from the candidate catheters, which are associated with a steepest descent value of the gradient among the candidate catheters;, 'a catheter pre- ...

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Номер записи: 52
03-02-2022 дата публикации

Injection system, syringe, and adapter

Номер: US20220031937A1
Автор: Shigeru Nemoto, Yumiko Fukikoshi
Принадлежит: Circulus Inc

An injection system includes: a syringe having a cylinder to be filled with a chemical liquid, a flange projecting laterally from the cylinder, an end portion through which the chemical liquid passes when the chemical liquid is pushed out, and a syringe screw portion formed on a side opposite to the end portion; an adapter for holding the syringe, the adapter having a receiving portion for receiving the cylinder, a regulating wall for abutting the flange, and an adapter screw portion engaged with the syringe screw portion; and an injection device provided with a holder to which the adapter is to be attached. In this injection system, a tightening direction by the syringe screw portion and the adapter screw portion is set in a direction toward the end portion.

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Номер записи: 53
19-01-2017 дата публикации

QUALITY ASSURANCE AND DATA COORDINATION FOR ELECTROMAGNETIC TRACKING SYSTEMS

Номер: US20170014192A1
Автор: BHARAT Shyam, BONILLAS VACA ANTONIO, DALAL SANDEEP M., DEHGHAN MARVAST EHSAN, Kruecker Jochen, KUNG CYNTHIA MING-FU, STANTON Douglas Allen, TAHMASEBI MARAGHOOSHMEL AMIR MOHAMMAD
Принадлежит:

An electromagnetic (“EM”) tracking configuration system employs an EM quality assurance (“EMQA”) () and EM data coordination (“DC”) system (). For the EMQA system (), an EM sensor block () includes EM sensor(s) () positioned and oriented to represent a simulated electromagnetic tracking of interventional tool(s) inserted through electromagnetic sensor block () into an anatomical region. As an EM field generator () generates an EM field () encircling EM sensor(s) (), an EMQA workstation () tests an EM tracking accuracy of an insertion of the interventional tool(s) through the EM sensor block () into the anatomical region. For the EMDC system (), as EM field generator () generates EM field () encircling a mechanical interaction of EM calibration tool(s) () with a grid () for guiding interventional tool(s) through gird () into an anatomical region, the electromagnetic data coordination workstation () establishes a coordination system for electromagnetically tracking an insertion of the interventional tool(s) through grid () into the anatomical region. 1. (canceled)2. (canceled)3. (canceled)4. (canceled)5. (canceled)6. An electromagnetic tracking configuration system comprising:an electromagnetic field generator operable to generate an electromagnetic field; andan electromagnetic data coordination system includingat least one electromagnetic calibration tool, each electromagnetic calibration tool including at least one electromagnetic sensor; and 'wherein, responsive to the electromagnetic field generator generating the electromagnetic field encircling a mechanical interaction of the at least one electromagnetic calibration tool with a grid including at least one channel for guiding at least one interventional tool into an anatomical region, the electromagnetic data coordination workstation is operable to establish a coordination system for electromagnetically tracking an insertion of the at least one interventional tool through the grid into the anatomical region.', ' ...

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Номер записи: 54
19-01-2017 дата публикации

Subject Target Tissue Specific Template Device

Номер: US20170014641A1
Автор: "OConnor John P.", Leong David
Принадлежит: ANALOGIC CORPORATION

A subject target tissue specific template device () that includes a block of material () and a plurality of apertures () in the material. An aperture of the plurality of apertures is located in the block of material at a location that corresponds to an area of interest identified in an image of an anatomical region of interest of a subject and transferred to an image of block of material with no aperture, which is geometrically aligned with the image of the anatomical region of interest of the subject. A method includes aligning, with a computing system, an image of anatomical tissue of interest with an image of a grid, marking at least one area of interest of tissue of interest within the image of tissue of interest, transferring the marking to the image of the grid, and saving the image of a grid with the marking as a file in an electronic format. 1. A subject target tissue specific template device , comprising:a block of material; anda plurality of apertures in the material,wherein an aperture of the plurality of apertures is located in the block of material at a location that corresponds to an area of interest identified in an image of an anatomical region of interest of a subject and transferred to an image of block of material with no aperture, which is geometrically aligned with the image of the anatomical region of interest of the subject.2. The subject target tissue specific template device of claim 1 , wherein multiple apertures of the plurality of apertures are located in the block of material at locations that correspond to areas of interest identified in the image of the anatomical region of interest of the subject and transferred to the image of block of material with no apertures claim 1 , which is geometrically aligned with the image of the anatomical region of interest of the subject.3. The subject target tissue specific template device of claim 1 , wherein the aperture has a diameter claim 1 , wherein the diameter has a dimension that passes a ...

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Номер записи: 55
17-01-2019 дата публикации

MEDICAL INJECTION AND SUCTION DEVICE

Номер: US20190015576A1
Автор: Tan Ta-Lun
Принадлежит: Benepet Co., Ltd.

A medical injection and suction device includes: a housing that encloses a driving motor; a syringe mount disposed on a wall of an upper side of the housing; a plurality of valves disposed on the wall of the upper side of the housing and on a side of the syringe mount; a slider that moves toward or away from the housing and is disposed on a lateral side of the housing; a driving rod connected to the slider; and at least one slide rod. The driving rod extends through a wall of the lateral side of the housing. An end of the driving rod is connected to the driving motor. The driving motor drives the driving rod to move the slider. An end of the at least one slide rod is connected to the wall of the lateral side of the housing. The slider is disposed in a slidable manner on the slide rod. 1. A medical injection and suction device comprising:a housing that encloses a driving motor,a syringe mount disposed on a wall of an upper side of the housing;a plurality of valves disposed on the wall of the upper side of the housing and on a side of the syringe mount;a slider that moves toward or away from the housing and is disposed on a lateral side of the housing; the driving rod extends through a wall of the lateral side of the housing,', 'an end of the driving rod is connected to the driving motor, and', 'the driving motor drives the driving rod to move the slider, and, 'a driving rod connected to the slider, wherein'} an end of the at least one slide rod is connected to the wall of the lateral side of the housing, and', 'the slider is disposed in a slidable manner on the slide rod., 'at least one slide rod, wherein'}2. The medical injection and suction device according to claim 1 , whereinthe syringe mount fixes a syringe to the housing,the plurality of valves closes and opens a plurality of catheters connected to the syringe, andthe slider is connected to a plunger of the syringe and pushes and pulls the plunger of the syringe to inject and suction liquids.3. The medical ...

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Номер записи: 56
17-01-2019 дата публикации

ENHANCED STYLET FOR DRUG DEPOT INJECTOR

Номер: US20190015653A1
Автор: Koch Brian D., Snyder Lloyd M.
Принадлежит:

A pellet delivery system is provided that comprises a needle having an inner surface defining a passageway. The needle has a first portion that extends along a longitudinal axis and a curved second portion comprising an opening that is in communication with the passageway. The second portion extends transverse to the longitudinal axis. A pellet is positioned in the passageway. A plunger is slidably positioned in the passageway. The plunger comprises a shaft having a rounded tip configured to push the pellet through the first and second portions and out of the opening without the pellet becoming stuck within the passageway or the opening. Implants, systems, constructs, instruments and methods are disclosed. 1. (canceled)2. A system for delivering a plurality of solid drug pellets , the system comprising: a proximal end,', 'a distal end comprising an opening, and', 'a passageway in communication with the opening; and, 'an epidural Tuohy needle configured to create a pathway to an epidural space, the needle comprisinga plurality of solid drug pellets in the passageway; a first end,', 'a second end,', 'a shaft portion extending from the first end to a position proximate the second end, and', 'a tip portion extending from the position proximate the second end to the second end, the tip portion having a bullet-nose shape comprising a progressively decreasing diameter from a maximum diameter at or adjacent the shaft portion to a minimum diameter at the second end so that a chamfer angle extends at an angle of 10° to 45° relative to a longitudinal axis of the plunger., 'a rigid plunger slidable in the passageway and the configured to push the plurality of solid drug pellets through the passageway and out of the opening, the plunger comprising3. The system of claim 2 , wherein the plunger is configured to push the plurality of solid drug pellets through the passageway and out of the opening without the plurality of solid drug pellets becoming stuck in the passageway or the ...

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Номер записи: 57
16-01-2020 дата публикации

High Precision Syringe with Removable Pump Unit

Номер: US20200016331A1
Автор: Lee Chao Young, Lee Frederick, Mao Zhenhua, Zhang Mei
Принадлежит:

A digital syringe is used with conventional polymer disposable syringe construction to be practical in the medical environment. Errors associated with the larger volumes of the syringes (which exacerbate minor errors in plunger position) and the flexibility and dimensional variations of the polymer plungers are accommodated by direct measurement of the syringe plunger position rather than indirect measurement of motor position and inference of syringe plunger position. This direct measurement eliminates mechanical tolerances (“stack up”) in the motor, gear train, and lead screw on plunger movement, an effect exacerbated by flexibility of the plunger and changes in syringe resistance and medicament viscosity, for example, with different medicaments or when the syringe is refrigerated. The digital syringe may be combined with the motor unit to provide additional versatility. 1. A sensor system for a measured delivery of a liquid medicament from a syringe of a type having a tubular barrel terminating at a needle adapter and including a closely fitting plunger activated elastomeric piston , the sensor system comprising:a housing receiving removably receiving the tubular barrel to extend along an axis from the housing;a plunger slidably received to move along the axis within the housing corresponding with motion of the elastomeric piston; andan electronic sensor attached to and stationary with respect to the housing and sensing a sensor element to provide direct measurement of motion of the plunger along the axis with respect to the housing to provide an electronic signal indicating movement of the plunger.2. The sensor system of wherein a portion of the plunger extends out of the housing for manual operation of the syringe by pressing on the plunger portion.3. The sensor system of wherein the housing provides outwardly extending flanges engaging with the user's fingers to assist with pressing on the plunger portion.4. The sensor system of further comprising a knob ...

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Номер записи: 58
21-01-2021 дата публикации

IMPLANTATION DEVICES, SYSTEM, AND METHODS

Номер: US20210016073A1
Автор: Billings Megan, Goddard Moses, Mills John, Sandrof Moses, Thanos Christopher
Принадлежит: VERTEX PHARMACEUTICALS INCORPORATED

Provided herein are devices, systems, and methods for subcutaneous membrane, encapsulation chamber, or reservoir implantation comprising or employing an implantation device configured to insert a membrane, encapsulation chamber, or reservoir into a subject. 1. A device for delivering cells or therapeutics to a subject , the device comprising:a first elongate body comprising a proximal portion, a distal portion, and an open volume configured to hold the cells or therapeutics, wherein the open volume leads to an opening at the distal portion, wherein the opening comprises a dimension equal to or greater than about 1 cm;a second elongate body comprising a proximal portion and a distal portion, wherein the distal portion of the second elongate body is sized to fit within the open volume of the first elongate body, and move relative to the first elongate body.2. The device of claim 1 , wherein the first elongate body is generally flat.3. The device of claim 1 , wherein the device comprises a volume equal to or less than about 40 cm{circumflex over ( )}3.4. The device of claim 1 , wherein a ratio of a width of the first elongate body to a height of the first elongate body is equal to or greater than about 5.5. The device of claim 1 , wherein the first elongate body comprises a generally uniform width and height.6. The device of claim 1 , wherein the open volume comprises a width about equal to a width of the opening.7. The device of claim 1 , wherein the open volume comprises a generally uniform width.8. The device of claim 1 , wherein the first elongate body comprises a gripping surface.9. The device of claim 1 , wherein the second elongate body comprises a gripping surface.10. The device of claim 1 , wherein the first elongate body further comprises a first elongate body grip.11. The device of claim 1 , wherein the second elongate body further comprises a second elongate body grip.12. The device of claim 1 , wherein the distal portion of the second elongate body ...

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Номер записи: 59
16-01-2020 дата публикации

ENDORECTAL PROBE DEVICE FOR EFFECTING RADIATION TREATMENT OF COLORECTAL CANCEROUS TISSUE IN THE RECTUM OF A HUMAN OR ANIMAL SUBJECT

Номер: US20200016428A1
Автор: BELLEZZO Murillo, BERBEE Maaike, PAIVA FONSECA Gabriel, RENIERS Brigitte, VAN LIMBERGEN Evert, VERHAEGEN Frank
Принадлежит:

The invention relates to the radiation treatment of colorectal cancerous tissue in the rectum of a human or animal subject. In particular the invention relates to an endorectal probe device for effecting radiation treatment of colorectal cancerous tissue in the rectum of a human or animal subject. Furthermore the invention relates to an afterloading apparatus for effecting radiation treatment of colorectal cancerous tissue in the rectum of a human or animal subject using an endorectal probe device according to the invention. Moreover the invention relates to a method for effecting radiation treatment of colorectal cancerous tissue in the rectum of a human or animal subject, wherein the method implements the endorectal probe device according to the invention. 1. Endorectal probe device for effecting radiation treatment of colorectal cancerous tissue in the rectum of a human or animal subject , the endorectal probe device comprising:an endorectal catheter probe having an elongated body with a distal probe end and a proximal probe end, which endorectal catheter probe being arranged to be inserted with its proximal probe end within the rectum towards the colorectal cancerous tissue site in the rectum;the elongated body of the endorectal catheter probe having at least one longitudinal catheter bore extending from the distal probe end towards the proximal probe end, the at least one longitudinal catheter bore being arranged in guiding an energy emitting source towards the colorectal cancerous tissue site for delivering a certain preplanned amount of radiation energy at one or more pre-determined dwell positions near or at the colorectal cancerous tissue site; as well asan endorectal tube having a hollow elongated body with a distal tube end and an open proximal tube probe end, which hollow endorectal tube being arranged to be inserted with its open proximal tube end within the rectum and against the colorectal cancerous tissue site in the rectum, and the hollow endorectal ...

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Номер записи: 60
21-01-2021 дата публикации

ADJUSTABLE BRACHYTHERAPY TEMPLATE AND TEMPLATE HOLDER

Номер: US20210016104A1
Автор: CAVANAUGH Sean
Принадлежит:

Brachytherapy templates and template holders can be adjustable relative to a patient's anatomy. One template includes a disposable portion with an aperture layer that includes first apertures and a patient contact layer that includes an adhesive on a surface thereof. The patient contact layer is formed from a flexible material. The template also includes a reusable portion that includes aperture plates. A locking mechanism can lock catheters firmly in place. One template holder includes a template compartment retainer constructed to hold a brachytherapy template, and a perineum attachment component is connected to the template compartment retainer by a connecting portion. The perineum attachment component includes a perineum attachment portion formed from a flexible material. 1. A brachytherapy template holder , comprising:a template compartment retainer constructed to hold a brachytherapy template; anda perineum attachment component connected to the template compartment retainer by a connecting portion, wherein the perineum attachment component includes a perineum attachment portion formed from a flexible material.2. The brachytherapy template holder of claim 1 , wherein the perineum attachment portion includes adhesive application areas formed of a material capable of bonding with an adhesive.3. The brachytherapy template holder of claim 1 , wherein:the template compartment retainer includes a first opening and the perineum attachment portion includes a second opening, and wherein a cross-sectional area of the second opening is equal to or greater than a cross-sectional area of the first opening; andthe brachytherapy template further comprises a brachytherapy template comprising apertures, wherein the brachytherapy template is disposed within the template compartment retainer such that longitudinal axes of the apertures are within the first opening and the second opening.4. The brachytherapy template holder of claim 1 , further comprising:displacing rods connected ...

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Номер записи: 61
28-01-2016 дата публикации

DRUG DELIVERY DEVICE AND METHODS HAVING A DRUG CARTRIDGE

Номер: US20160022973A1
Автор: Belton Antonio, Clay Danielle L., Corrigan Sean, Grider Keith, Lau Michael Honsing, Leatzow Derek, Merves Michael, Snyder Lloyd, Soucia Jeffrey A.
Принадлежит:

Various embodiments of a device, a kit and method for delivering a drug depot are disclosed. The device comprises a housing including a lower body, an upper body, a ring member; and a drug cartridge. The lower body defines a lower body channel. The upper body defines an upper body channel. The drug cartridge defines a depot channel. The ring member is disposed extending upward from an annular step surface of the lower body toward a housing upper end. The ring member includes indicia indicating a characteristic of one or more drug depots in the drug cartridge. A plunger has a push rod for expelling the drug depot through the cannula to a site in the patient. A kit comprises the above components. A method includes assembling the components including selecting a ring member having indicia corresponding to one or more drug depots in the drug cartridge. 1. A device for delivering a drug depot to a site beneath the skin of patient via a cannula having a proximal end and a distal end , the proximal end of the cannula having an opening to receive the drug depot , the distal end of the cannula being configured for insertion to the site beneath the skin of the patient and having an opening for passage of the drug depot , the device comprising:a housing including a lower body, an upper body, a ring member; and a drug cartridge, said housing having a housing upper end, a housing lower end and a longitudinal direction defined as extending from said housing upper end to said housing lower end;said lower body having a lower body bottom end, a lower body upper end, and an annular step surface extending inward from an outer periphery of said lower body, and said lower body defining a lower body channel extending in said longitudinal direction;said lower body channel having a lower body channel first end open to said lower body upper end and a lower body channel second end open to said lower body bottom end;said lower body bottom end having a coupling configuration for engaging the ...

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Номер записи: 62
28-01-2016 дата публикации

DRUG DELIVERY DEVICE AND METHODS HAVING AN OCCLUDING MEMBER

Номер: US20160022974A1
Автор: Belton Antonio, Clay Danielle L., Corrigan Sean, Grider Keith, Lau Michael Honsing, Leatzow Derek, Merves Michael, Snyder Lloyd, Soucia Jeffrey A.
Принадлежит:

Drug depot delivery devices and methods for delivering a drug depot to a site beneath the skin of a patient are provided. In various embodiments the device has a housing having a top housing end, and a bottom housing end. The housing defines a housing channel. The device has a drug cartridge defining a depot channel aligned with the housing channel and configured to slidably accept the drug depot. The drug cartridge has at least a first occluding device configured to occlude the depot channel at a first position such that the drug depot cannot pass through the depot channel without force applied to the drug depot sufficient to deflect the first occluding device. The bottom end of the housing has a coupling configuration for engaging a cannula. A plunger has a push rod to expel the drug depot through the occluding device and the cannula. 1. A device for delivering a drug depot to a site beneath the skin of patient via a cannula having a proximal end and a distal end , the proximal end of the cannula having an opening to receive the drug depot , the distal end of the cannula being configured for insertion to the site beneath the skin of the patient and having an opening for passage of the drug depot , the device comprising:a housing having a top housing end, and a bottom housing end, said housing further defining a housing channel having a housing channel first open end open to said top housing end and a second housing channel open end open to said bottom housing end;a drug cartridge defining a depot channel aligned with said housing channel and configured to slidably accept the drug depot, said drug cartridge having at least a first occluding device configured to occlude said depot channel at a first occluding position such that the drug depot cannot pass through said depot channel at said first occluding position without force, greater than that of gravity, applied to the drug depot sufficient to deflect said first occluding device an amount permitting passage of ...

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Номер записи: 63
28-01-2016 дата публикации

DRUG DELIVERY DEVICE AND METHODS HAVING A RETAINING MEMBER

Номер: US20160022975A1
Автор: Belton Antonio, Clay Danielle L., Corrigan Sean, Grider Keith, Lau Michael Honsing, Leatzow Derek, Merves Michael, Snyder Lloyd, Soucia Jeffrey A.
Принадлежит:

Various embodiments of a device, a kit and method for delivering a drug depot are disclosed. The device comprises a housing including a lower body, an upper body, a ring member; and a drug cartridge. The lower body defines a lower body channel. The upper body defines an upper body channel. The drug cartridge defines a depot channel. The ring member is disposed extending upward from an annular step surface of the lower body toward a housing upper end. The ring member includes indicia indicating a characteristic of one or more drug depots in the drug cartridge. A plunger has a push rod for expelling the drug depot through the cannula to a site in the patient. A kit comprises the above components. A method includes assembling the components including selecting a ring member having indicia corresponding to one or more drug depots in the drug cartridge. 1. A device for delivering a drug depot to a site beneath the skin of patient via a cannula having a proximal end and a distal end , the proximal end of the cannula having an opening to receive the drug depot , the distal end of the cannula being configured for insertion to the site beneath the skin of the patient and having an opening for passage of the drug depot , the device comprising:a housing having a top housing end, and a bottom housing end, said housing further defining a housing channel having a housing channel first open end open to said top housing end and a second housing channel open end open to said bottom housing end;a drug cartridge defining a depot channel aligned with said housing channel and configured to slidably accept the drug depot, said drug cartridge having at least a first occluding device configured to at least partially occlude said depot channel at a first occluding position such that the drug depot cannot pass through said depot channel at said first occluding position without force, greater than that of gravity, applied to the drug depot sufficient to deflect said first occluding device an ...

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Номер записи: 64
26-01-2017 дата публикации

APPARATUS AND METHOD FOR LOADING RADIOACTIVE SEEDS INTO CARRIERS

Номер: US20170021191A1
Автор: Brachman David, Fram Evan, McBride Heyoung, Nakaji Peter, Thomas Theresa, Youssef Emad
Принадлежит:

An apparatus and method for loading brachytherapy carriers with radioactive seeds in order to implement brachytherapy treatment protocols with more precise and predictable dosimetry. These apparatuses and methods enable a medical team to create a radionuclide carrier for each patient and tumor reliably, reproducibly and efficiently. 1. (canceled)2. An apparatus comprising:a carrier comprising collagen and configured to receive a radioactive seed; a first surface;', 'an opposing second surface parallel to the first surface;', 'a receiving surface between the first and second surfaces at first ends of each of the first surface and the second surfaces;', 'a loading port at an entrance of a loading channel extending through the receiving surface of the loader, the loading port defining a first alignment interface on an outer surface of the receiving surface; and', 'a loading bed between the first and second surfaces sized to support the carrier on the loading bed;, 'a loader having an injection channel configured to contain a radioactive seed, the injection channel and the loading channel having substantially equal diameters;', 'a distal end having a second alignment interface sized and shaped to engage with the first alignment interface of the loading port; and', 'a plunger having a first end comprising a longitudinal rod extending at least partially within the injection channel and a second end outside of the injection channel configured for engagement by a human operator in order to move the longitudinal rod within the injection channel;, 'an injection device havingwherein with at least a portion of the injection device inserted into the loading port such that the first alignment interface engages the second alignment interface, the radioactive seed is movable out of the injection device into the collagen carrier on the loading bed in response to movement of the second end of the plunger towards the distal end of the injection device.3. An apparatus comprising:a bio- ...

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Номер записи: 65
25-01-2018 дата публикации

Single-head power injector with contrast media leakage management

Номер: US20180021505A1
Автор: James R. Small, Robert J. McGraw
Принадлежит: Liebel Flarsheim Co LLC

A power injector ( 200 ) is disclosed that includes a number of features to address leakage of contrast media from a syringe that may occur while operating the power injector ( 200 ), for instance when loading fluid into a syringe after being installed on a powerhead ( 210 ) of the injector ( 200 ) and/or when purging air from such a syringe. One or more drainage channels ( 240 ) may be incorporated on a faceplate mounting ( 234 ) which in turn receives a faceplate ( 310 ), which in turn receives a syringe. A cover assembly ( 260 ) may utilize a form-in-place gasket ( 274 ) between its top cover ( 262 ) and its bottom cover ( 290 ). A bezel ( 330 ) includes an overlay ( 334 ) that is disposed over a touch screen display ( 380 ) that is aligned with a display aperture ( 264 ) through the top cover ( 262 ), and the bezel ( 330 ) may include a gasket ( 350 ) to seal against the top cover ( 262 ).

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Номер записи: 66
10-02-2022 дата публикации

BIODEGRADABLE ADHESIVE WITH RADIOISOTOPES

Номер: US20220040499A1
Автор: III Charles, Kepe Vladimir, Martin
Принадлежит:

A radioactive biodegradable adhesive system can include a first component and a second component. The second component can include a radioactive material. The first component and the second component are configured to polymerize to form a radioactive bolus. A method for treating a patient in need of brachytherapy can include providing the radioactive biodegradable adhesive system. The first component and the second component can be applied to a predetermined location to form the radioactive bolus at the predetermined location. 1. A radioactive biodegradable adhesive system , comprising:a first component; anda second component including a radioactive material;wherein the first component and the second component are configured to polymerize to form a radioactive bolus.2. The radioactive biodegradable adhesive system of claim 1 , wherein the first component and the second component are provided in an insertion device.3. The radioactive biodegradable adhesive system of claim 2 , wherein the insertion device includes a first chamber claim 2 , a second chamber claim 2 , an insertion tip claim 2 , and a force applicator claim 2 , the first chamber containing the first component and the second chamber containing the second component.4. The radioactive biodegradable adhesive system of claim 2 , wherein the insertion device is configured to separately and simultaneously dispense the first component and the second component out of a distal end of the insertion tip.5. The radioactive biodegradable adhesive system of claim 1 , wherein the radioactive material includes one of an alpha emitter and a beta emitter.6. The radioactive biodegradable adhesive system of claim 1 , wherein the radioactive material includes yttrium-90.7. The radioactive biodegradable adhesive system of claim 1 , wherein the first component is a monomer and the second component is a radioactive catalyst.8. The radioactive biodegradable adhesive system of claim 7 , wherein the radioactive catalyst includes a ...

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Номер записи: 67
24-01-2019 дата публикации

Adhesive and Peripheral Systems and Methods for Medical Devices

Номер: US20190022337A1
Автор: Gray, Jr. Larry B.
Принадлежит:

A system is disclosed. The system includes a reservoir for containing a fluidic medium, the reservoir including a front surface, a resilient cylindrical flexure portion connected to the front surface, the resilient cylindrical flexure portion comprising an accordion-like structure that is able to expand and contract to change an interior volume within the resilient cylindrical flexure portion, a central passageway within the resilient cylindrical flexure, and a collection chamber connected to the central passageway. Also, a system including a reservoir, a plunger head located within the reservoir, a plunger arm connected to the plunger head, a driving shaft connected to the plunger arm, and a motor connected to the driving shaft, the motor controllable to move the drive shaft in a first motion and a second motion so as to move the advance plunger head and retract the plunger head within the reservoir. 1. A system comprising: a resilient cylindrical flexure portion that is able to expand and contract to change an interior volume within the resilient cylindrical flexure portion, wherein the resilient cylindrical flexure portion comprising a first end and a second end;', 'a central tube within the resilient cylindrical flexure portion extending from the first end to the second end of the resilient cylindrical flexure portion;', 'a collection chamber directly connected to the central tube; and', 'a pumping chamber coupled in fluid communication with the collection chamber and the central tube, wherein fluid flows from the collection chamber through the central tube and directly into the pumping chamber,', "wherein during a pumping mechanism's compression stroke, a pumping actuation member applies force directly on to, and deforms, a collection chamber wall forcing fluid to flow through the central tube and into the pumping chamber."], 'a reservoir comprising2. The system of claim 1 , further comprising a disposable housing assembly adapted to be secured to a user's skin ...

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Номер записи: 68
22-01-2015 дата публикации

DETECTING UNINTENTIONAL MOTOR MOTION AND INFUSION DEVICE INCORPORATING SAME

Номер: US20150025499A1
Автор: Campbell Alexander S., CHOW Steve, KOW Hsiao-Yu S., Mattson Nichole R., Trock Adam S.
Принадлежит:

Apparatus are provided for infusion devices and related systems and operating methods. An exemplary system includes a motor, a sensing arrangement coupled to the motor to provide output indicative of a detected characteristic of the motor when the sensing arrangement is enabled, and a module coupled to the sensing arrangement to periodically enable the sensing arrangement while the motor is idle and detect potential unintended motion of the motor based on the output from the sensing arrangement while periodically enabling the sensing arrangement. In some embodiments, the motor includes a rotor configured such that its rotation provides translational displacement of a plunger in a fluid reservoir, and the sensing arrangement includes one or more sensors configured to provide output indicative of a detected magnetic field of the rotor magnet. 1. A system comprising:a motor;a sensing arrangement coupled to the motor to provide output indicative of a detected characteristic of the motor when the sensing arrangement is enabled; anda module coupled to the sensing arrangement to periodically enable the sensing arrangement while the motor is idle and detect potential unintended motion of the motor based on the output from the sensing arrangement while periodically enabling the sensing arrangement.2. The system of claim 1 , wherein:the motor includes a rotor;the sensing arrangement includes one or more sensors to detect a characteristic of the rotor; andthe module detects potential unintended rotation of the rotor based on outputs from the one or more sensors while periodically enabling the sensing arrangement.3. The system of claim 2 , wherein:the motor includes a magnet coupled to the rotor; andthe one or more sensors detect a magnetic field of the magnet.4. The system of claim 3 , wherein the module detects the potential unintended rotation of the rotor by:obtaining an initial sensor output state from the one or more sensors in response to initially enabling the sensing ...

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Номер записи: 69
23-01-2020 дата публикации

RADIOATIVE MICROSPHERE AND PREPARATION METHOD THEREOF

Номер: US20200023088A1
Автор: Chang Fu-Yu, Liu Chien-Liang, Tsai Yu-Yu
Принадлежит:

Provided is a radioactive microsphere including a glass sphere core. The glass sphere core includes a first seed, a second seed and a diffusion region extending inwardly from an outer surface of the glass sphere core, with the second seed distributed in the diffusion region. The first seed and the second seed become radioactive after being activated by neutrons to produce radiations including β-rays or γ-rays, or simultaneously β-rays and γ-rays. A preparation method of a radioactive microsphere is also provided. 1. A radioactive microsphere , comprising:a glass sphere core comprising a first seed, a second seed, and a diffusion region extending inwardly from an outer surface of the glass sphere core,wherein the second seed is distributed in the diffusion region, and the first seed and the second seed become radioactive after being activated by neutrons to produce radiations comprising β-rays or γ-rays, or simultaneously β-rays and γ-rays.2. The radioactive microsphere of claim 1 , further comprising a shell layer coating the glass sphere core.3. The radioactive microsphere of claim 2 , wherein the shell layer is formed by a material comprising one of an organic material and an inorganic material claim 2 , or a combination thereof.4. The radioactive microsphere of claim 1 , wherein the glass sphere core comprises a radioactive therapeutic agent.5. The radioactive microsphere of claim 1 , wherein the first seed comprises one of yttrium claim 1 , aluminum and silicon claim 1 , or a combination thereof.6. The radioactive microsphere of claim 1 , wherein the second seed before being activated by the neutrons is at least one selected from the group consisting of: phosphorus claim 1 , calcium claim 1 , sodium claim 1 , rhenium claim 1 , scandium claim 1 , lanthanum claim 1 , cerium claim 1 , praseodymium claim 1 , neodymium claim 1 , promethium claim 1 , samarium claim 1 , europium claim 1 , gadolinium claim 1 , terbium claim 1 , dysprosium claim 1 , holmium claim 1 , ...

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Номер записи: 70
29-01-2015 дата публикации

Drug reconstitution system

Номер: US20150029816A1
Автор: Derek Brandt, Franck Robin, Thomas Gerber, Uwe Beyer
Принадлежит: SENSILE PAT AG

A drug reconstitution device comprising a disposable liquid transfer unit ( 18 ) and a reusable control and drive unit ( 16 ) removably connectable to the liquid transfer unit, the liquid transfer unit including a housing ( 26 ), a docking interface ( 30 ) configured for coupling at least one of first and second constituent containers ( 2, 4 ) to the housing ( 10 ), and a pump engine ( 28 ) and fluid flow system ( 36 ) configured for transferring liquid from the first constituent container ( 2 ) to the second constituent container ( 4 ). The control and drive unit comprises a pump drive ( 22 ) configured to drive the pump engine during a liquid transfer action, the pump drive comprising a transmission output coupling ( 34 ) removably engaged with a transmission input coupling ( 50 ) of the pump engine ( 28 ) when the liquid transfer unit and control and drive unit are connected.

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Номер записи: 71
04-02-2016 дата публикации

Imaging apparatus for brachytherapy or biopsy

Номер: US20160030130A1
Автор: Amir Mohammad TAHMASEBI MARAGHOOSH, Ehsan DEHGHAN MARVAST, Shyam Bharat, Vijay Parthasarathy
Принадлежит: Koninklijke Philips NV

The invention relates to an imaging apparatus ( 24 ) for imaging an introduction element ( 17 ) like a needle or a catheter for performing a brachytherapy or a biopsy. A tracking unit ( 3, 4 ) tracks the location of the introduction element within a living being ( 2 ), an imaging unit ( 6 ) like an ultrasound imaging unit generates an image showing an inner part of the living being, which includes the tracked location of the introduction element, based on the tracked location, and a display ( 7 ) displays the image. During the brachytherapy or biopsy the display can always show the introduction element, without requiring a manual control. For instance, it is not necessary that a physician manually controls the position and image plane of the imaging unit. This allows for an accurate and fast insertion of the introduction element into the living being such that a target region is reliably reached.

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Номер записи: 72
04-02-2016 дата публикации

System and Method for Improved High Dose Radiation Therapy Treatment Planning

Номер: US20160030768A1
Автор: Demanes Jeff, Ennis Daniel B., Langman Deborah, Srinivasan Subashini
Принадлежит:

The present invention includes a catheter for providing contrast under magnetic resonance imaging (MRI). The catheter includes an elongated tubular member having a proximal end, a distal end and lumen. The catheter further includes a solution of saline and at least one contrast agent, where the solution is sealed within at least a portion of the catheter lumen. 2. The catheter of claim 1 , wherein the contrast agent is a gadolinium-containing contrast agent.3. The catheter of claim 1 , wherein the contrast agent is gadobenate dimeglumine.4. The catheter of claim 1 , wherein the contrast agent is gadopentetate dimeglumine.5. The catheter of claim 1 , wherein the concentration of contrast agent is between 0.6-2.22 mmol/L.6. The catheter of claim 1 , wherein the solution pattern signature comprises a variation in contrast agent concentration along a length of the tubular member.7. The catheter of claim 1 , wherein the solution pattern signature comprises at least one interruption of the solution along a length of the tubular member claim 1 , such that the solution is absent at the interruption.8. The catheter of claim 7 , wherein the interruption comprises a gel.9. The catheter of claim 7 , wherein the interruption comprises a bubble.10. The catheter of claim 7 , wherein the interruption comprises a pinched region of the tubular member.11. The catheter of claim 7 , wherein the interruption comprises a wall.12. The catheter of claim 11 , wherein the elongated tubular member includes multiple compartments claim 11 , wherein at least two of the compartments are isolated from each other by a wall within the lumen.13. A method of visualizing a channel positioned in the tissue of a subject claim 11 , the method comprising:positioning at least one channel in the tissue of a subject;inserting into each channel a catheter having a solution including saline and at least one contrast agent sealed within the lumen of the catheter, such that the solution forms a pattern signature; ...

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Номер записи: 73
01-02-2018 дата публикации

INJECTION DEVICE

Номер: US20180028798A1
Автор: CONLON Colin, Fenlon Derek, LAUNOIS Pascal, MOYNE Martina, RYAN Owen William
Принадлежит:

An injection device for injecting a solid dose formulation into a human or animal body, the injection device comprising an actuator () having a cassette mounting portion (); a cassette holder () having a cassette storage portion; and a cassette selectively movable between the cassette storage portion and the cassette mounting portion, wherein, the cassette () comprises a solid dose formulation and the actuator is receivable in the cassette holder to selectively move the cassette between the cassette storage portion and the cassette mounting portion. 1. An injection device for injecting a solid dose formulation into a human or animal body , the injection device comprising:an actuator having a cassette mounting portion;a cassette holder having a cassette storage portion; anda cassette selectively movable between the cassette storage portion of the cassette holder and the cassette mounting portion of the actuator,wherein, the cassette comprises a solid dose formulation and the actuator is receivable by the cassette holder to selectively move the cassette between the cassette storage portion and the cassette mounting portion.2. An injection device according to claim 1 , wherein the cassette storage portion comprises a plurality of releasable retaining elements for selectively retaining the cassette.3. An injection device according to claim 1 , wherein the cassette mounting portion comprises a bayonet fitting for receiving the cassette.4. An injection device according to claim 3 , wherein the bayonet fitting of the cassette mounting portion and the releasable retaining elements of the cassette storage portion are co-operable such that rotation of the actuator relative to the cassette holder releases the releasable retaining elements to facilitate selective movement of the cassette from the cassette storage portion to the cassette mounting portion and/or from the cassette mounting portion to the cassette storage portion.5. An injection device according to claim 3 , ...

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Номер записи: 74
29-01-2015 дата публикации

DELIVERY APPLICATOR FOR RADIOACTIVE STAPLES FOR BRACHYTHERAPY MEDICAL TREATMENT

Номер: US20150031935A1
Автор: DiPetrillo Thomas A., Hollows Matthew, Munro John J., Schehr Kevin, Wazer David E., Zambrano Krissie K.
Принадлежит:

An instrument used for brachytherapy delivery in the treatment of cancer by radiation therapy including a handle having first and second handle actuators; an end effector; and an instrument shaft that connects the handle with the end effector. The end effector has first and second adjacent disposed staple cartridges that each retain a set of staples. The first mechanism is for holding standard staples in a first array, and dispensing the standard staples under control of the corresponding first handle actuator. The second mechanism is for holding radioactive source staples in a second array, and dispensing said radioactive source staples under control of the corresponding second handle actuator. The actuating device is removably attachable to an actuator arm on a proximal end. A staple applicator cartridge holder is attached to the actuator arm on a distal end. The staple applicator cartridge is mountable in the holder and having a plurality of slots for mounting of radioactive source staples therein. An anvil therein crimps the staples. 1. An instrument used for brachytherapy delivery in the treatment of cancer by radiation therapy , said instrument comprising:a handle having first and second handle actuators;an end effector;an instrument shaft that connects the handle with the end effector;said end effector comprised of first and second adjacent disposed cartridges that each retain a set of staples;said first cartridge for holding standard staples in a first array, and dispensing said standard staples under control of the corresponding first handle actuator;said second cartridge for holding radioactive source staples in a second array, and dispensing said radioactive source staples under control of the corresponding second handle actuator;said first and second cartridges being retained in a substantially parallel array so that the standard staples close the incision at a surgical margin while the source staples are secured adjacent thereto.2. The instrument of ...

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Номер записи: 75
29-01-2015 дата публикации

PISTON PUMP AND DEVICE FOR FEEDING AND METERING A FLUID FOR MEDICAL PURPOSES BY MEANS OF A PISTON PUMP

Номер: US20150032054A1
Автор: EBERHARD Dietmar
Принадлежит: B. BRAUN MELSUNGEN AG

A piston pump is described for pumping a fluid, comprising at least two cylinders each having a piston which is movable inside the associated cylinder along the longitudinal axis of the cylinder by means of a drive, wherein cylinders are attached to a common pump flange. In each cylinder a chamber is formed having a volume that changes when the associated piston is moved in the cylinder. The pump flange extends along the direction of motion of the pistons, and at least one inlet port and one outlet port are attached to the pump flange, whose longitudinal axes run along the pump flange. A central valve plate is attached to the side of the pump flange facing away from the cylinders that bear on the pump flange and continuously rotates transversely to the pump flange during pumping operation of the piston pump. Respective passages are introduced to the pump flange in the region of each inlet and outlet port, and cylinder openings are introduced to the pump flange in the region of each cylinder. The valve plate has at least two cavities on the flange side, of which a first cavity coincides, upon rotation of the valve plate to a first angular position, with a cylinder opening of a first cylinder and a passage of the outlet port, while the second cavity coincides in this first angular position with the passage of the inlet port and a cylinder opening in the second cylinder. The first cavity then coincides, upon rotation of the valve plate to a second angular position, with the passage in the outlet port and a cylinder opening in the second cylinder, while the second cavity coincides in this second angular position with the passage in the inlet port and a cylinder opening in the first cylinder. 115-. (canceled)16. Piston pump for pumping a fluid , comprising:a pump flange;at least two cylinders, each cylinder having a piston which is movable inside the associated cylinder along the longitudinal axis of the cylinder by a drive, wherein the cylinders are attached to the pump ...

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Номер записи: 76
30-01-2020 дата публикации

INFUSION DEVICE FOR ADMINISTERING A MEDICAL FLUID TO A PATIENT AND METHOD FOR OPERATING AN INFUSION DEVICE

Номер: US20200030526A1
Автор: Wolff Rémy
Принадлежит:

An Infusion device () for administering a medical fluid to a patient, comprises: a housing (); a receptacle () arranged on the housing () for receiving a syringe (); a pusher device () movable in a pushing direction (P) for acting onto a piston () of a syringe () received on the receptacle (); a drive element () connected to the pusher device (), the drive element () being longitudinally movable relative to the housing () for moving the pusher device () along the pushing direction (P); a driving rod () having a screw thread () and being rotatable about a rotational axis (R); an electric drive device () for rotating the driving rod (); a clutching device () connected to the drive element () and being actuatable, by an actuation device (), to engage, in a clutched state, with the screw thread () of the driving rod () for translating a rotational movement of the driving rod () into a longitudinal movement of the drive element () along the driving rod (), and to disengage, in an unclutched state, from the driving rod (); a brake device () constituted to act, in an activated state, onto the drive element () for braking the drive element () relative to the housing () and to allow, in a deactivated state, a longitudinal movement of the drive element () relative to the housing (); a control device () to control the electric drive device () and the brake device (); and a sensing device () for detecting an actuation state of the clutching device (). Herein, the control device () is constituted, when the sensing device () detects that the clutching device () is actuated to change from the unclutched state to the clutched state, to perform a control sequence during which the control device () controls the electric drive device () to rotate the driving rod () for a predetermined duration or for a predetermined angle of rotation while the brake device () is in the activated state. 1. An infusion device for administering a medical fluid to a patient , comprising:a housing,a ...

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Номер записи: 77
30-01-2020 дата публикации

DRUG PELLET DELIVERY SYSTEM AND METHOD

Номер: US20200030545A1
Автор: Snyder Lloyd M.
Принадлежит:

A drug pellet delivery system includes a housing having a cavity. A cartridge is positioned within the cavity and includes a body having a channel. The body includes a first pair of rails and a second pair of rails. A plunger is slidably disposed in the housing and the cartridge. The plunger is configured to move a drug depot through the channel and out of the housing. Kits and methods of use are disclosed. 1. (canceled)2. A device for delivering a drug depot , the device comprising:the drug depot; a surface;', 'a depot pathway at least partially defined by a recess in the surface, the depot pathway having a longitudinal axis, the drug depot in the depot pathway;', a first planar surface parallel to the longitudinal axis of the depot pathway; and', 'a second planar surface tapered towards the depot pathway; and, 'a first pair of rails protruding from the surface in a second direction opposite the first direction, the first pair of rails spaced apart by and outward of the depot pathway, the first pair of rails configured to block and redirect a plunger to maintain alignment of the plunger through the depot pathway, each said rail of the first pair of rails comprising, 'a second pair of rails protruding from the surface in the second direction, the second pair of rails spaced apart by and outward of the depot pathway, the second pair of rails configured to block and redirect the drug depot to maintain alignment of the drug depot through the depot pathway, each said rail of the second pair of rails comprising a planar surface parallel to the longitudinal axis of the depot pathway;, 'a cartridge comprising a first projection between the first pair of rails;', 'a second projection between the second pair of rails; and', 'a wall over at least a portion of the depot pathway., 'a cover removably attached to the cartridge, the cover being translucent such that the drug depot is visible in the depot pathway through the cover, the cover comprising3. The device of claim 2 , ...

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Номер записи: 78
04-02-2021 дата публикации

SYRINGE ROLLING APPARATUS AND METHOD

Номер: US20210030950A1
Автор: COWAN KEVIN, SPOHN MICHAEL
Принадлежит:

A syringe rolling apparatus for initial rolling of a rolling diaphragm syringe from an unrolled state to a rolled state has a pressure jacket configured for receiving an empty, unrolled rolling diaphragm syringe, a piston reciprocally movable within the pressure jacket and configured for contacting an end wall of the syringe rolling diaphragm syringe to initiate a rolling of a flexible sidewall of the rolling diaphragm syringe, and a seal assembly configured for engaging an open discharge neck of the rolling diaphragm syringe. The seal assembly is in fluid communication with a source of pressurized fluid to pressurize an interior of the rolling diaphragm syringe during a distal movement of the piston. A method for initial rolling of a rolling diaphragm syringe from an unrolled state to a rolled state is also disclosed. 1. A method for rolling of a rolling diaphragm syringe from an unrolled state to a rolled state , the method comprising:advancing a piston of a rolling apparatus to engage an end wall of the rolling diaphragm syringe, wherein the rolling diaphragm syringe comprises a proximal end comprising the end wall configured to engage the piston of the rolling apparatus, an open distal end comprising a discharge neck, and a flexible sidewall extending between the proximal end and the distal end along a longitudinal axis;pressurizing an interior of the rolling diaphragm syringe to a first pressure by applying a pressurized fluid into an interior thereof; andfurther advancing the piston, thereby causing at least a portion of the sidewall of the rolling diaphragm syringe to roll upon itself in a radially inward direction, thereby forming a rolling diaphragm syringe in the rolled state.2. The method of claim 1 , further comprising releasing an amount of the pressurized fluid from the interior of the rolling diaphragm syringe during advancing of the piston of the rolling apparatus to maintain the first pressure in the interior of the rolling diaphragm syringe.3. The ...

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Номер записи: 79
11-02-2016 дата публикации

THROMBECTOMY CATHETER DEPLOYMENT SYSTEM

Номер: US20160038163A1
Автор: Aasen Nicole Jaye, Abbott Martyn Stuart, Ball Douglas James, Bonnette Michael John, Croll Walter Charles, Cummings David Charles, Grant Chad Nicolas, III Ernest Ralph, Karpinski James Fredrick, Kneip Daniel Joseph, Rogers Jeffrey William, Scherger, Teschendorf John Lloyd, Thor Eric Joel, Weisel Stephen Earl, West David Woodruff
Принадлежит: BOSTON SCIENTIFIC SCIMED, INC.

A thrombectomy catheter deployment for operation of a thrombectomy catheter may include a stand alone drive unit and a disposable pump/catheter assembly which is manually placed into a carriage assembly in the drive unit. The pump/catheter assembly may have a plurality of preconnected components including a tubular structure and a thrombectomy catheter connected thereto. A barcode reader may sense specific operational data pertaining to an individual pump and may provide an interface for operation of the reciprocating linear actuator. 1. A catheter infusion assembly , comprising:an infusion catheter attached to a pump;wherein the pump is configured to insert into a drive unit;wherein the drive unit is configured to actuate the pump; andwherein the pump and catheter are coupled together prior to insertion into the drive unit.2. The infusion assembly of claim 1 , wherein the pump is selected from the group comprising a pulsatile pump claim 1 , an actuation pump claim 1 , a reciprocating pump claim 1 , an infusion pump and a piston pump.3. The infusion assembly of claim 1 , wherein the infusion catheter is fixed to the pump.4. The infusion assembly of claim 1 , wherein the pump includes a piston claim 1 , and wherein the drive unit is configured to actuate the piston.5. The infusion assembly of claim 1 , wherein the catheter claim 1 , the pump or both the catheter and the pump includes one or more data elements configured to operate the drive unit.6. The infusion assembly of claim 5 , wherein the data elements are configured to operate at least the pump.7. The infusion assembly of claim 5 , wherein the data elements are configured to calibrate the drive unit.8. The infusion assembly of claim 5 , wherein the data elements include a bar code.9. The infusion assembly of claim 1 , wherein catheter infusion assembly further comprises a manifold assembly claim 1 , the manifold assembly including an infusion port claim 1 , an effluent port claim 1 , or both and infusion and ...

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Номер записи: 80
24-02-2022 дата публикации

Portable infusion pump with pinch/squeeze pumping action

Номер: US20220054742A1
Автор: David Neese, Marc D. GOLDMAN, Paul M. DiPerna
Принадлежит: Modular Medical Inc

A device for infusing a medicament into a patient includes a disposable component having a collapsible reservoir for holding the medicament, a cannula, and an elastomeric tube connected in fluid communication between the reservoir and the cannula. A manipulator is mounted on a chassis for engagement with the elastomeric tube. The manipulator includes a piston and respective pinchers upstream and downstream from the piston for a close/open open/close changeover operation. In concert therewith, the piston cyclically advances and withdraws relative to a platen to thereby alternatingly dilate/constrict the tube section. When the upstream pincher is open, the piston withdraws to create a low fluid pressure, pLo, in the tube section to draw medicament into the tube. Alternately, when the downstream pincher is open, the piston is advanced to create a high fluid pressure, pHi, on the tube to infuse medicament into the patient.

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Номер записи: 81
24-02-2022 дата публикации

INFUSION PUMP WITH VALVE COMPENSATION

Номер: US20220054745A1
Автор: Eitan Boaz, PESACH Gidi, RASOWSKY Amir, SHTOLTZ Ram
Принадлежит:

An infusion pump () includes a plunger () configured to squeeze a section of an infusion tube (). A proximal valve (), proximal to the plunger, ascends to allow infusion fluid intake from a reservoir to the infusion tube and descends to inhibit infusion fluid intake from the reservoir to the infusion tube. A distal valve (), distal to the plunger, ascends to allow infusion fluid flow past the distal valve, and descends to inhibit infusion fluid flow past the distal valve. A controller () controls the plunger, proximal valve, and distal valve by initiating descending of the plunger concurrently with or prior to the ascending of the distal valve, such that the descending of the plunger compensates for suction produced by the ascending of the distal valve, thereby reducing backflow of fluid from the subject. Other applications are also described. 1. An infusion pump comprising:a plunger configured to squeeze a section of an infusion tube; ascend and thereby allow infusion fluid intake from a reservoir to the infusion tube, and', 'descend and thereby inhibit infusion fluid intake from the reservoir to the infusion tube;, 'a proximal valve located proximally to said plunger, said proximal valve configured to ascend and thereby allow infusion fluid flow past the distal valve, and', 'descend and thereby inhibit infusion fluid flow past the distal valve; and, 'a distal valve located distally to said plunger, said distal valve configured toa controller configured to control said plunger, said proximal valve, and said distal valve and thereby, to control infusion fluid intake from the reservoir and infusion fluid delivery to a subject,wherein controlling delivery of infusion fluid to the subject comprises initiating descending of said plunger concurrently with or prior to the ascending of said distal valve, such that the descending of said plunger compensates for suction produced by the ascending of said distal valve, thereby reducing backflow of fluid from the subject.2. The ...

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Номер записи: 82
06-02-2020 дата публикации

SHARP TURNING STEERABLE NEEDLE

Номер: US20200038054A1
Автор: Yim Mark
Принадлежит:

Disclosed are steerable needles having a shaft that can be controllably buckled, a steering head positioned at a distal end of the shaft, a transmission for controlling the orientation of the steering head, and a base at the end of the shaft, the base optionally comprising a controller for controlling the transmission. Also disclosed are methods of using the disclosed steerable needles. 1. A steerable comprising:a shaft comprising a beam capable of being controllably buckled;a steering head positioned at a distal end of the shaft;a transmission for controlling the orientation of the steering head; anda base positioned at a proximal end of the shaft.2. The steerable needle according to claim 1 , wherein the steering head comprises a beveled tip.3. (canceled)4. The steerable needle according to claim 1 , wherein the steering head defines a lumen formed therethrough.5. The steerable needle according to claim 1 , wherein the transmission comprises at least one control linkage claim 1 , at least one shaft claim 1 , at least one tape spring claim 1 , or any combination thereof.6. (canceled)7. (canceled)8. The steerable needle according to claim 1 , wherein the beam comprises a flattened tube claim 1 , and the transmission comprises at least one control linkage contained within said flattened tube.9. The steerable needle according to claim 1 , wherein at least one of the beam and transmission comprises a pre-curved mechanical bias.10. (canceled)11. (canceled)12. The steerable needle according to claim 1 , wherein the beam comprises a first tape spring and wherein the transmission comprises a second tape spring.13. (canceled)14. The steerable needle according to claim 12 , wherein the first tape spring and the second tape spring have pre-curved mechanical biases opposite to one another.15. The steerable needle according to claim 12 , wherein the first and second tape springs are oriented such that they form a closed tube.16. The steerable needle according to claim 12 , ...

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Номер записи: 83
06-02-2020 дата публикации

Fluid path set bolus control device

Номер: US20200038647A1
Автор: James A. Dedig, Ralph Schriver
Принадлежит: Bayer HealthCare LLC

A bolus control device for use with an injection device, the bolus control device including a valve body having a proximal end opposite a distal end. The valve body defines a fluid channel therethrough to allow a passage of medical fluid from the proximal end to the distal end. A connector is provided at the proximal end and configured for connecting to a fluid inlet line. A connector subassembly is provided at the distal end and configured for connecting to a fluid outlet line. A compressible check valve is disposed within the fluid channel, such that the compressible check valve is adjustable to control a cracking pressure at which the compressible check valve closes.

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Номер записи: 84
12-02-2015 дата публикации

AUTO-INJECTOR

Номер: US20150045734A1
Автор: Cowperthwaite Jake, Enga Agnete, Flamm Alex, Formosa Daniel, Freitag Eric, Lipford Brian, Lozeau Kevin Richard, MCLOUGHLIN Martin John, Melzi Ilario, Schumann Michael
Принадлежит: UCB PHARMA SA

Provided is a cassette unit suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit has a housing defining a cassette unit housing cavity and a needle projection aperture. The housing cavity is arranged for receipt of a syringe suitable for delivery of a drug to a patient. The syringe has a barrel for containing a volume of a liquid drug formulation, the barrel defining a flange at the rear end thereof and a forward shoulder at the forward end thereof. The cassette unit includes one or more shoulder support features for supporting the forward shoulder of the syringe. In use, the one or more shoulder support features act to direct a major part of an applied load path to travel through the shoulder at the forward end of the syringe and lesser load to pass through the flange at the rear end thereof. 1. A cassette unit for use with an auto-injector having an electrically powered drive unit , said cassette unit comprising:a cassette unit housing defining a cassette unit housing cavity and a needle projection aperture; a barrel for containing a volume of a liquid drug formulation, said barrel defining a flange at the rear end thereof and a forward shoulder at the forward end thereof;', 'a hollow needle at a front end of said barrel, said hollow needle defining a needle tip for dispensing of said liquid drug formulation; and', 'a plunger that is axially movable within the barrel; and, 'said cassette unit housing cavity arranged for receipt of a syringe comprisingone or more shoulder support features for supporting said forward shoulder of the syringe.2. A cassette unit according to claim 1 , further comprising a needle cover defining a needle sheath for sheathing of said needle tip claim 1 , wherein said one or more shoulder support features locate between the needle cover and the forward shoulder of the syringe.3. A cassette unit according to claim 2 , wherein said needle cover is provided with a needle sheath cover for covering ...

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Номер записи: 85
16-02-2017 дата публикации

MEDICAL INJECTOR SYSTEM

Номер: US20170043082A1
Автор: Cowan Kevin P., HAURY JOHN H., NEFF JARED E.
Принадлежит:

A syringe includes a body and a plunger movably disposed within the body. The syringe may be used with an injector including a drive member. The drive member preferably includes at least one pin adapted to form a retractable abutting connection with an interior of a plunger to enable the drive member to retract the plunger with the body of the syringe. 12-. (canceled)3. A syringe comprising:a syringe body; and an annular base member comprising a cylindrical wall extending in a longitudinal direction and having a proximal end, a distal end, and a circumferentially continuous inner surface and an outer surface between the proximal end and the distal end,', 'a retaining shoulder recessed within the cylindrical wall between the extending around the circumference of the inner surface of the cylindrical wall; and', 'a plurality of flanges extending proximally from the retaining shoulder and projecting radially inwardly from the inner surface of the cylindrical wall., 'a plunger movably disposed within the syringe body, the plunger comprising41. The syringe of claim , wherein the plurality of flanges are radially spaced apart around the inner surface of the cylindrical wall.51. The syringe of claim , wherein the plurality of flanges are evenly spaced apart around the inner surface of the cylindrical wall.61. The syringe of claim , wherein the plurality of flanges are randomly spaced apart around the inner surface of the cylindrical wall.71. The syringe of claim , wherein the plurality of flanges extend radially inward to decrease a diameter formed by the inner surface.81. The syringe of claim , wherein the plurality of flanges are configured to engage an abutment section of a piston configured for moving the plunger within the body of the syringe.81. The syringe of claim , wherein the plurality of flanges are configured to engage an abutment section of a piston distally from a circumferential ledge at the proximal end of the cylindrical wall.91. The syringe of claim , ...

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Номер записи: 86
15-02-2018 дата публикации

COMPACT MEDICAL INFUSION PUMPS

Номер: US20180043088A1
Автор: Adams Grant A., Lacy Christopher A., WILKOWSKE Eric J.
Принадлежит: SMITHS MEDICAL ASD, INC.

A compact medical infusion pump includes a base unit and a compact pump mechanism coupled to the base unit. The compact pump mechanism also includes a carriage member shaped to support a medical syringe, is movable in a first linear direction relative to the base unit, and is fixed to a first guide rod arm. The mechanism further includes a plunger driver shaped to selectively engage a plunger portion of the medical syringe, is moveable in a second linear direction opposite the first linear direction, and is fixed to a second guide rod arm. The mechanism also includes a rotatable drive member that is centrally located with respect to the base unit and is driven by a drive train assembly. The rotatable drive member engages both the first guide rod arm and the second guide rod arm to translate the carriage member and the plunger driver in opposite directions. 1. A compact medical infusion pump , comprising:a base unit including a first stationary side panel and a second stationary side panel, and a drive train assembly generally centrally located in the base unit; and a carriage member shaped to support a medical syringe, movable in a first linear direction relative to the base unit, and fixed to a first guide rod arm that extends through the first stationary side panel;', 'a plunger driver shaped to selectively engage a plunger portion of the medical syringe, moveable in a second linear direction opposite the first linear direction, and fixed to a second guide rod arm that extends through the second stationary side panel; and', 'a rotatable drive member centrally located with respect to the base unit and driven by the drive train assembly, that engages both the first guide rod arm and the second guide rod arm to translate the carriage member and the plunger driver in opposite directions when rotated., 'a compact pump mechanism coupled to the base unit, including2. The compact medical infusion pump of claim 1 , wherein the second guide rod arm has a length extending ...

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Номер записи: 87
16-02-2017 дата публикации

Treatment planning system

Номер: US20170043180A1
Автор: Ananth Ravi, Cynthia Ming-fu KUNG, Ehsan DEHGHAN MARVAST, Falk Uhlemann, Jochen Kruecker, Shyam Bharat, Thomas Erik AMTHOR
Принадлежит: Koninklijke Philips NV, Sunnybrook Health Sciences Centre

The generation of the pattern and for the adaptation to the specific geometry requires a lot of manual work. It is an object of the invention to simplify the workflow for the clinician during treatment planning. This object is achieved by a treatment planning system configured for determining a set of catheter or needle insertion positions to be used during treatment comprising. The treatment planning system comprises an image providing module for providing a medical image from which at least one treatment target structure can be derived. Further the treatment planning system comprises a pattern providing module for providing one or a set of standard patterns for catheter or needle insertion comprising a plurality of catheter or needle insertion positions, wherein the catheter or needle positions relate to treatment positions in the at least one treatment target structure.

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Номер записи: 88
01-05-2014 дата публикации

MODULAR APPLICATOR FOR BRACHYTHERAPY

Номер: US20140121443A1
Автор: Martens Tommy Robert Oscar, van de Wardt Cor, van Erp Wilhelmus Petrus Martinus Maria, van Wijck Gaetan Stephan Marie
Принадлежит: Nucletron Operations B.V.

Embodiments of the present disclosure relate to a modular applicator for enabling a brachytherapy treatment, comprising a central core and an outer sleeve, wherein the central core is adapted with a fixation mechanism for affixing the outer sleeve to the central core, wherein the outer sleeve is manufactured from a substantially rigid or shapeable material. 1. A modular applicator for enabling a brachytherapy treatment , comprising a central core and an outer sleeve , the central core being adapted with a fixation mechanism for affixing the outer sleeve to the central core , wherein the outer sleeve is manufactured from a substantially rigid or shapeable material.2. The applicator according to claim 1 , wherein the core is cylindrical claim 1 , non-cylindrical or shapeable in use.3. The applicator according to claim 1 , wherein a material of the sleeve is settable.4. The applicator according to claim 1 , wherein at least a portion of the outer surface of the sleeve is irregular.5. The applicator according to claim 4 , wherein the said at least the portion of the outer surface comprises a set of local depletions or bumps for providing local areas of under pressure.6. The applicator according to claim 1 , wherein the sleeve is transparent.7. The applicator according to claim 1 , further comprising a plurality of customized sleeves.8. The applicator according to claim 7 , wherein the customized sleeves are adapted to be manufactured in vivo.9. The applicator according to claim 8 , wherein the customized sleeves are at least partially manufactured from a shapeable material.10. The applicator according to claim 1 , wherein a distal portion of the sleeve is shapeable.11. The applicator according to claim 9 , wherein the distal portion of the sleeve is provided with sub-portions capable of lateral displacement with respect to each other.12. The applicator according to claim 1 , wherein the fixation mechanism comprises a snap fit or a rotational fit.13. The applicator ...

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Номер записи: 89
01-05-2014 дата публикации

MODULAR APPLICATOR FOR BRACHYTHERAPY

Номер: US20140121444A1
Автор: Martens Tommy Robert Oscar, van de Wardt Cor, van Erp Wilhelmus Petrus Martinus Maria, van Wijck Gaetan Stephan Marie
Принадлежит: Nucletron Operations B.V.

A modular applicator for enabling a brachytherapy treatment comprising a central element and one or more of peripheral elements, wherein the central element is adapted with a fixation mechanism having a core for affixing the said peripheral elements thereto, wherein the fixation mechanism prevents a rotational displacement of the peripheral elements attached to the core of the fixation element with respect to the central element. 1. A modular applicator for enabling a brachytherapy treatment comprising a central element and one or more of peripheral elements , wherein the central element is adapted with a fixation mechanism having a core for affixing the said peripheral elements thereto , wherein the fixation mechanism prevents a rotational displacement of the peripheral elements attached to the core with respect to the central element.2. The applicator according to claim 1 , wherein the fixation mechanism comprises a pre-oriented slot.3. The applicator according to claim 1 , wherein the fixation mechanism is rigidly connected to the central element.4. The applicator according to claim 1 , wherein the fixation mechanism is displaceably connected to the central element.5. The applicator according to claim 2 , wherein the slot is three-dimensional.6. The applicator according to claim 1 , wherein the fixation mechanism comprises a pre-oriented substantially cylindrical core adapted to be affixed on the central element.7. The applicator according to claim 6 , wherein the central element comprises a plurality of substantially cylindrical conduits.8. The applicator according to claim 6 , wherein the said core is adapted to cooperate with an outer sleeve.9. The applicator according to claim 8 , wherein the sleeve is shapeable.10. The applicator according to claim 9 , wherein the sleeve is inflatable.11. The applicator according to claim 6 , wherein at least a portion of the outer surface of the sleeve is irregular.12. The applicator according to claim 11 , wherein the said ...

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Номер записи: 90
01-05-2014 дата публикации

AUTOMATED INTRAOPERATIVE ULTRASOUND CALIBRATION

Номер: US20140121501A1
Автор: Abolmaesumi Purang, BURDETTE Clif E., CHEN Thomas Kuiran, Fichtinger Gabor, HEFFTER Tamas, Lasso Andras
Принадлежит: QUEEN'S UNIVERSITY AT KINGSTON

An ultrasound calibration phantom comprises a portion including at least one fiducial structure having a selected geometric arrangement; a portion adapted for mechanical coupling of the ultrasound calibration phantom to a transrectal ultrasound (TRUS) stepper; and a guide for at least one surgical instrument, the guide being mechanically coupled to the fiducial structure and/or to the TRUS stepper at a selected pose relative to the fiducial structure. A calibration method uses the calibration phantom and provides automatic, intraoperative calibration of ultrasound imaging systems. The invention is useful in ultrasound-guided clinical procedures. 1. An ultrasound calibration phantom , comprising:a portion including at least one fiducial structure having a selected geometric arrangement;a portion adapted for mechanical coupling of the ultrasound calibration phantom to a transrectal ultrasound (TRUS) stepper; anda guide for at least one surgical instrument, the guide being mechanically coupled to the fiducial structure and/or to the TRUS stepper at a selected pose relative to the fiducial structure.2. The ultrasound calibration phantom of claim 1 , wherein the portion including the at least one fiducial structure further includes an ultrasound coupling medium.3. The ultrasound calibration phantom of claim 1 , further comprising a portion that interfaces with an ultrasound probe.4. The ultrasound calibration phantom of claim 3 , wherein the ultrasound probe is a transrectal ultrasound (TRUS) probe.5. The ultrasound calibration phantom of claim 1 , wherein the at least one fiducial structure comprises a plurality of fiducial lines in a selected geometric arrangement.6. The ultrasound calibration phantom of claim 5 , wherein the at least one fiducial structure comprises at least one Z-wire structure.7. The ultrasound calibration phantom of claim 1 , comprising:a first fiducial structure having a selected geometric arrangement, the first fiducial structure corresponding to ...

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Номер записи: 91
01-05-2014 дата публикации

Clutched-Gear Handle and System for Fiducial Deployment

Номер: US20140121677A1
Автор: Campbell Tríona, Clancy Michael, Keady Fionan, McGrath Darach, Mulcahy Patrick, Toomey Ciarán
Принадлежит: Cook Medical Technologies LLC

Embodiments include a fiducial deployment system with a handle configured for actuation of same. A fiducial may include one or more protuberances configured to engage one or more slots in a needle of the system. The needle may be configured to deliver a plurality of fiducials to a target location in serial fashion, one at a time. In certain embodiments, echogenic placement of fiducials may present certain advantages. The handle includes a clutched-gear actuation mechanism configured for incrementally or otherwise controlled deploying one or more fiducials at a time by advancing a stylet through and/or retracting the body of a slotted needle in which fiducials are disposed with a fiducial protrusion extending into the needle slot, which also includes retaining structures that do not impede the needle lumen. 1. A clutched-gear handle for a fiducial deployment system including an advancement mechanism comprising:an actuation member and an elongate first handle member, including a central longitudinal axis defined by an elongate outer body of the first handle member, the outer body including a body lumen longitudinally disposed therethrough;where a stylet extends through at least a portion of the first handle member along or generally aligned with the central longitudinal axis;an axle mounted rotatably in the first handle member, disposed adjacent to and transverse of the central longitudinal axis of the first handle member;a clutched gear mounted rotatably to the axle by a one-way clutch bearing allowing unidirectional rotation of the clutched gear around the axle, and a drive gear fixed to the axle;where the actuation member is disposed in reciprocating mechanical communication with one of the drive gear or the clutched gear; anda rack member engaged with and generally longitudinally aligned with the stylet, where a surface of the rack member mechanically communicates with a surface of the other of the drive gear or the clutched gear such that actuation of the ...

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Номер записи: 92
03-03-2022 дата публикации

IMPLANT SYRINGE

Номер: US20220062608A1
Автор: Kneer Roland, Kneer Stephan, Koller Walter
Принадлежит:

An implant syringe includes a cannula, a storage element for receiving a solid material implant, and an outer sleeve with a radially projecting front gripping section which are axially movable together. An inner sleeve affords axial slits through which radial webs on the outer sleeve engage, and also includes a rod-shaped piston. The rod-shaped piston may be advanced through the storage element into the cannula such that a gap remains between the tip of the cannula and the head end of the piston. The cannula is rigidly connected to the storage element to form a cannula unit, that the webs on the outer sleeve are attached to an annular receiving member within the inner sleeve and that the cannula unit is insertable into the receiving member and is lockable therein, where a solid material implant can be inserted into the storage element.

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Номер записи: 93
19-02-2015 дата публикации

Detecting conditions associated with medical device operations using matched filters

Номер: US20150051573A1
Автор: Juan M. Alderete, Jr., Matthew I. Haller, R. Marie Tieck
Принадлежит: Medtronic Minimed Inc

Apparatus are provided for infusion devices and related operating methods. An exemplary device includes a sensing arrangement to provide an output indicative of a characteristic that is influenced by operation of the device, and a control module that is coupled to the sensing arrangement to apply a matched filter corresponding to a condition associated with the operation of the device to the output of the sensing arrangement and detect that condition based on the filtered output. In one example, the device includes a motor coupled to a plunger of a reservoir and operable to displace the plunger, wherein the characteristic is a force opposing displacement of the plunger and the control module detects an occlusion condition in a fluid path from the reservoir based on filtered force measurements.

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Номер записи: 94
19-02-2015 дата публикации

QUALITY ASSURANCE SYSTEM AND METHOD FOR NAVIGATION-ASSISTED PROCEDURES

Номер: US20150051861A1
Автор: BHARAT Shyam, Kruecker Jochen, KUNG CYNTHIA MING-FU
Принадлежит: KONINKLIJKE PHILIPS N.V.

A calibration system includes a channel block () having a plurality of channels () formed therein. The channels are configured to correspond to locations where treatment devices are inserted for treatment of a patient. The channels are dimensioned to restrict motion of the treatment devices. A tracking system () is configured to monitor a position of a treatment device () inserted in one or more of the channels. The tracking system is configured to generate tracking data for the at least one treatment device for comparison with an expected position for the treatment device. 1. A calibration system for a tracking system , comprising:a channel block having a plurality of channels formed therein, the plurality of channels being configured to correspond to locations where treatment devices are inserted for treatment of a patient, the channels being dimensioned to restrict motion of the treatment devices; andthe tracking system configured to monitor a position of at least one treatment device inserted in at least one of the channels of the plurality of channels, the tracking system being configured to generate tracking data for the at least one treatment device for comparison with an expected position based on the true positional data for the at least one treatment device.2. The system as recited in claim 1 , wherein the plurality of channels are arranged to correspond with a grid employed for locating the treatment devices.3. The system as recited in claim 2 , wherein the grid includes holes which are aligned with the plurality of channels such that the at least one treatment device is inserted in one of the channels by passing through one of the holes in the grid.4. The system as recited in claim 2 , further comprising a stepper for positioning and configuring one of the grid and the channel block.5. The system as recited in claim 1 , wherein the tracking system includes an electromagnetic tracking system and the at least one treatment device includes an ...

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Номер записи: 95
14-02-2019 дата публикации

MAGNETIC PRESSURE JACKET FOR FLUID INJECTOR

Номер: US20190046719A1
Автор: Campbell Patrick, DEDIG James, GRUBIC HERBERT, SCHRIVER RALPH
Принадлежит:

A fluid injector having at least one injector head with a front end configured to releasably receive the at least one syringe is described. The fluid injector further includes at least one pressure jacket releasably associated with the front end of the at least one injector head for securing the at least one syringe during an injection procedure. A connection mechanism releasably connects the at least one pressure jacket to the front end of the at least one injector head. The connection mechanism includes at least one electromagnet. 1. A fluid injector comprising:at least one injector head having a front end configured to releasably receive at least one syringe;at least one pressure jacket releasably associated with the front end of the at least one injector head for securing the at least one syringe during an injection procedure; anda connection mechanism for releasably connecting the at least one pressure jacket to the front end of the at least one injector head,wherein the connection mechanism comprises at least one electromagnet.2. The fluid injector of claim 1 , wherein the electromagnetic force of the at least one electromagnet is controlled by a controller of the fluid injector.3. The fluid injector of claim 1 , wherein the at least one injector head comprises the at least one electromagnet.4. The fluid injector of claim 3 , wherein the at least one electromagnet is configured to magnetically interact with at least one magnet associated with the at least one pressure jacket.5. The fluid injector of claim 4 , wherein the poles of the at least one electromagnet on the front end of the at least one injector head is opposite to the poles of the at least one magnet associated with the at least one pressure jacket.6. The fluid injector of claim 4 , wherein the at least one magnet associated with the at least one pressure jacket comprises a ferromagnetic material.7. The fluid injector of claim 1 , wherein the at least one injector head is configured to releasably ...

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Номер записи: 96
14-02-2019 дата публикации

Compact platform for accurate drug delivery

Номер: US20190046721A1
Автор: Blagoy P. Iliev, Jacob Brinkert, Jeffrey A. Shimizu, Klaas Kerkhof, Robert Fienieg, Ronald F. A. Tonnie te Vruchte - Haj Modiri, Ventzeslav Petrov lordanov
Принадлежит: Progenity Inc

In some implementations, a fluid delivery device includes a compressible dispensing chamber defining a dispensing volume and including a dispensing chamber inlet in fluid communication with a reservoir and a dispensing chamber outlet in fluid communication with an environment. A first one-way valve at the reservoir outlet or the dispensing chamber inlet selectively allows flow of the substance from the reservoir to the compressible dispensing chamber and a second one-way valve at the dispensing chamber outlet selectively allows flow of the substance from the dispensing chamber to the environment. An actuator selectively compresses the compressible dispensing chamber to decrease the dispensing volume and expel the substance in the dispensing chamber through the dispensing chamber outlet.

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Номер записи: 97
14-02-2019 дата публикации

TREATMENT ASSESSMENT DEVICE

Номер: US20190046814A1
Автор: GERAATS Jacobus Sigbertus Marie, HAUTVAST Guillaume Leopoid Theodorus Frederik, Senden Dave
Принадлежит:

The invention relates to a treatment assessment device () for assessing a treatment of a subject, wherein a current treatment is tracked by a tracking unit () and previous conformance values being indicative of previous degrees of conformance of previous treatments with previous treatment plans are provided. A visualization unit () generates a visualization being indicative of a current degree of conformance of the current treatment with the current treatment plan in relation to the previous degrees of conformance based on the tracking of the current treatment, the current treatment plan and the provided previous conformance values. The visualization can be shown on a display such that a physician can see how well the current treatment conforms to the treatment plan in comparison to the degree of conformance achieved in previous treatments, thereby providing an assessment of the quality of the current treatment in relation to previous treatments. 1. A treatment assessment device for assessing a treatment of a subject , wherein a current treatment is tracked by a tracking unit and the treatment assessment device comprises:a treatment plan providing unit for providing a current treatment plan,a conformance values providing unit for providing previous conformance values being indicative of previous degrees of conformance of previous treatments with previous treatment plans, anda visualization unit for generating a visualization being indicative of a current degree of conformance of the current treatment with the current treatment plan in relation to the previous degrees of conformance based on the tracking of the current treatment, the current treatment plan and the provided previous conformance values.2. The treatment assessment device as defined in claim 1 , wherein the treatment is performed by using an interventional device claim 1 , wherein the tracking of the current treatment includes determining the position of the interventional device during the current ...

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Номер записи: 98
25-02-2016 дата публикации

SYSTEM AND METHOD FOR DETECTING OCCLUSIONS IN AN INFUSION PUMP

Номер: US20160051758A1
Автор: Harris Paul, Kruse Geoffrey A., Rosinko Michael J.
Принадлежит:

Occlusions in a delivery line of an infusion pump can be detected by measuring pressure differentials in the pump over short periods of time in order to minimize the effects of long term systematic sensor changes. In a delivery mode such as basal insulin delivery where a small portion of a volume of fluid is delivered, pressure readings can be obtained before and after the motor move to deliver each portion and compared. The differentials after one or more motor moves can be compared to determine whether an occlusion is present. In a delivery mode such as bolus insulin delivery in which an entire volume of fluid is delivered, pressure differentials can be obtained for consecutive deliveries at a common point in the delivery cycle of each delivery. Comparison of these pressure values can be used to determine whether an occlusion is present. 120-. (canceled)21. A method of detecting occlusions in an infusion pump comprising a disposable infusion cartridge and a pump device , the infusion cartridge including a collapsible reservoir for containing a fluid and a substantially rigid shell disposed over the collapsible reservoir and forming an interior volume between an outside surface of the collapsible reservoir and an inside surface of the shell , the infusion cartridge further including a delivery mechanism having a spool slidingly disposed in a bore , the spool including a main section and a distal section axially displaceable relative to the main section with a collapsible volume formed between a seal on the main section and a seal on the distal section , the pump device configured to selectively receive the infusion cartridge and cooperate with the infusion cartridge to deliver fluid from the reservoir into the collapsible volume and to a patient , the pump device including a drive mechanism powered by a motor and selectively engageable with the spool to impart controlled axial movements to the spool to deliver fluid to the patient , wherein the method comprises: ...

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Номер записи: 99
25-02-2021 дата публикации

System For Syringe Engagement To An Injector

Номер: US20210052809A1
Автор: CASTILLO LUIS, Lang Charles, SCHULTE STEPHEN, Swenglish Christopher
Принадлежит:

An injector system for injecting fluid includes a syringe and an injector. The syringe includes a body and a plunger movably disposed within the body. The plunger has at least one flexible leg extending toward the rearward end of the body. The injector has a housing with a front plate, a drive member at least partially disposed within the housing and operable to engage the plunger, and a syringe release assembly operable to release the syringe. The syringe assembly includes a syringe release gear that forms an enclosure for receiving the syringe when the syringe is fully seated within the housing and a plunger release tube surrounding at least a portion of the drive member. The plunger release tube has a first end rotationally engaged with the syringe release gear. Rotation of the syringe release assembly releases the at least one flexible leg from the drive member. 1. A syringe for interfacing with a fluid injector and a syringe release mechanism for releasing the syringe from operable engagement with the fluid injector , the syringe comprising:an elongated tubular body comprising a rearward end and a forward end;a plunger movably disposed within the tubular body, the plunger having at least one flexible leg extending toward the rearward end of the tubular body and configured to be releasably connectable to a piston of the fluid injector;a syringe engagement flange positioned toward the rearward end of the tubular body and extending around a circumference of the tubular body, the syringe engagement flange comprising a syringe drive paw configured to engage the syringe release mechanism,wherein the syringe drive paw transfers movement imparted to the syringe by a user into the syringe release mechanism to release both the syringe and the plunger regardless of an axial position of the engaged plunger with the piston of the fluid injector.2. The syringe of claim 1 , wherein the movement imparted to the syringe by the user is rotational movement.3. The syringe of claim ...

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Номер записи: 100