Applications of MiR-125b for diagnosing and treating acute myeloid leukemia

The invention discloses an application of miR-125b in the diagnosis or treatment of acute myeloid leukemia. The invention applies the miR-125b to the early diagnosis of acute myeloid leukemia (AML) according to the nature that the expression level of the miR-125b in the marrow of an acute myeloid leukemia early patient is far higher than that of the miR-125b in the marrow of a normal person. The invention discloses the high expression of the miR-125b in an AML early patient or recurrent patient, particularly in M3 type and the normal expression of the miR-125b in a complete-remission patient, thereby developing the new application direction of the miR-125b. That is to say, the miR-125b can not only correctly predict the prognosis of AML, but also serve as the drug target for curing AML.

Method and device for calibrating reference voltage inside integrated circuit chip

The embodiment of the invention discloses a method and device for calibrating the reference voltage inside an integrated circuit chip. The calibrating method comprises the steps that a constant supply voltage connected with the integrated circuit chip serves as a benchmark voltage of analog-digital conversion initialization of the integrated circuit chip, and the reference voltage in the integrated circuit chip is calibrated according to the benchmark voltage, wherein the process of calibrating the reference voltage in the integrated circuit chip comprises the step of collecting the reference voltage values in the integrated circuit chip and the step of setting the reference voltage calibration values into the reference voltage values. Correspondingly, the embodiment of the invention further discloses a method and device for calibrating data collected by the integrated circuit chip with the internal reference voltage being calibrated with the calibrating method. According to the method ...

Applications of MiRNA for diagnosing central nervous system leukaemia and kit thereof

The invention discloses an application of MiRNAs in the diagnosis of central nervous system leukemia and the kit for the same. According to the close relationship between eight miRNAs, namely miR-7, miR-198, miR-663, miR-126, miR-345, miR-222, miR-30b and miR-551a, and the recurrence of CNSL, the invention uses eight MiRNAs as biological indexes to carry out early diagnosis of ALL recurrent CNSL. The invention can not only correctly predict the CNSL prognosis of a patient, but also provide a useful tool for proposing a clinic therapeutic scheme. The invention also provides the kit containing the specific primers of the eight miRNAs to carry out early diagnosis of ALL recurrent CNSL with convenient use, simple operation and correct prediction.

Underground coal mine mining floor water inrush monitoring method and system

The invention belongs to the technical field of mine water disaster prevention and control, and provides an underground coal mine mining floor water inrush monitoring method and system.The mining floor damage depth is calculated according to related index data of mining floor damage characteristics; calculating a water inrush coefficient according to the mining floor damage depth; determining a to-be-monitored area according to the water inrush coefficient; obtaining various monitoring data in the to-be-monitored area by comprehensively considering the morphological characteristics of the floor damage; according to the obtained various monitoring data and the projection pursuit theory, monitoring and early warning are conducted on mine mining floor water inrush; before monitoring, according to relevant index data of mining floor damage characteristics, the mining floor damage depth is calculated, according to the calculated mining floor damage depth, the water inrush coefficient is calculated ...

Method for judging turn-to-turn short circuit fault end of steam turbine generator rotor without pulling out retaining ring

The invention relates to a method for judging a turn-to-turn short circuit fault end of a steam turbine generator rotor without pulling out a retaining ring, which comprises the following steps of: testing and calculating on the basis of determining that turn-to-turn short circuit occurs in a specific set of coil in a positive winding or a negative winding by utilizing basic characteristics such as electrical parameters and spatial arrangement of a generator rotor winding; according to the method, whether the fault position of the rotor turn-to-turn short circuit is located at the excitation end or the steam end is accurately analyzed and judged, a data theoretical basis is provided for determining the fault end and scientifically organizing and developing retaining ring pulling maintenance processing, the fault maintenance cost is greatly reduced, and good social benefits and economic benefits are achieved.

Method for preparing europium-labeled hydroxyapatite nano particle

The invention discloses a method of preparing an Eu-labelled nano-HAP, which is characterized in that calcium nitrate and monoammonium sulfate are taken according to the stoichiometric ratio of the hydroxyapatite produced in stoichiometry; the calcium nitrate is dissolved in the water solution of ethyl alcohol, and solution A is obtained by adding europium nitrate by quantity; solution B is obtained by dissolving monoammonium sulfate into the water solution of ethyl alcohol; solution A is dripped into solution B, the pH value of the mixed solution is regulated, and dispersant is added; a filter cake is obtained through sucking filtration, and the impurities are washed with a cleaner; the filter cake is dried through a freeze-drying method, for obtaining hydroxyapatite powder; the diameter of the powder is between 20mm to 150mm. The method of preparing an Eu-labelled nano-HAP provided by the invention has simple process which is easy to be controlled and raw materials which are easy to be ...

Method of mixed automatic request of retransmission based on orthogonal frequency division multiplex

Multi-task learning network training method and device, electronic equipment and storage medium

The invention provides a multi-task learning network training method and device, electronic equipment and a storage medium, and the method comprises the steps: inputting a panoramic segmentation training data set and a posture recognition training data set into a main shared sub-network of a multi-task learning network, and obtaining a feature map; inputting the feature map into a semantic branch sub-network and an instance segmentation sub-network of a multi-task learning network to obtain a semantic segmentation map, an instance center prediction map, an instance center regression map and a skeleton point recognition map; obtaining a panoramic segmentation image; and calculating the total loss of the multi-task learning network, and training the multi-task learning network according to the total loss. The panoramic segmentation training data set and the posture recognition training data set are adopted to train the multi-task learning network, so that the multi-task learning network can ...

Carbocisteine oral liquid and preparation method thereof

The invention relates to a carbocisteine oral liquid and a preparation method thereof. The oral liquid comprises carbocisteine accounting for 2% to 10% of the oral liquid, sodium hydroxide, an antioxidant, a solution stabilizer composition, and a flavoring agent, and has a pH value of 6.0 to 7.5. The oral liquid is prepared by the following steps: carrying out salt-forming reactions between carbocisteine and a sodium hydroxide solution, then dissolving the salts into water, adding an antioxidant, a solution stabilizer composition, and a flavoring agent, stirring, adding water to a metered volume, filtering, filling the solution into cans, and finally sterilizing the cans so as to obtain the oral liquid; wherein each can contains 10 to 120 mL of oral liquid. The oral liquid is widely used to treat thick phlegm or dys-expectoration caused by chronic bronchitis, bronchus asthma, and the like, and has the characteristics of stable property, long shelf life, and safer clinical application.

Device and method for judging working state of steam turbine generator hydrogen cooler

The invention relates to a device and a method for judging the working state of a steam turbine generator hydrogen cooler, which are characterized in that temperature and pressure sensors are additionally arranged at a hydrogen inlet, a hydrogen outlet, a water inlet and a water outlet of the hydrogen cooler to acquire temperature and pressure data of the hydrogen cooler and process the data; and then monitoring the heat transfer coefficient, the heat transfer material mass loss ratio and the heat transfer efficiency in the current state, comparing the heat transfer coefficient, the heat transfer material mass loss ratio and the heat transfer efficiency with the data in the healthy period, and identifying the scaling and leakage fault states of the hydrogen cooler. And the problem that the generating capacity is affected due to cooling efficiency reduction caused by the fact that hydrogen cooler faults are not found in time is solved.

Backlight module and display device

The invention provides a backlight module and a display device. The backlight module comprises a frame, a light guide plate, a light source module, resetting pieces and a first sliding portion. The light guide plate is accommodated in the frame and is provided with a light incident side, a second side, a light emergent side and a bottom side. The light incident side and the second side are opposite. The light emergent side and the bottom side are opposite. The light emergent side and the bottom side respectively adjoin the light incident side and the second side. The light source module is accommodated in the frame and arranged on the light incident side of the light guide plate. The resetting pieces are arranged and abut against the second side of the light guide plate. The first sliding portion is fixed to the frame and abuts against a third side of the light guide plate. The third side adjoins the light incident side and the second side. When the light guide plate displaces, the resetting ...

Electric power wiring anchor clamps

The utility model relates to an electric power wiring anchor clamps can effectively solve the problem that high -voltage testing wiring is inconvenient, have safe risk, and the technical scheme of its solution is, including the support, support upper portion is provided with the horizontally roof, and the roof below is provided with on the support can follow upper and lower slip of vertical direction and fixed adjusting screw, and the adjusting screw upper end is provided with the horizontally cardboard, constitutes the binding post's that awaits measuring centre gripping space between roof and the cardboard, support, roof, screw rod, cardboard all adopt electrically conductive metal material to make, the utility model discloses novel structure is unique, and is simple reasonable, easy production, and easy operation, with low costs, accessible adjusting screw remote operation has pull open the spatial distance between operator and the high voltage live body, and need not ascend a height ...

Method for identifying and judging loosening fault of end part of stator core of steam turbine generator

The invention relates to a method for identifying and judging a loosening fault of an end part of a stator core of a steam turbine generator, which comprises the following steps of: acquiring an interlayer temperature in a stator coil slot and an end part temperature measuring point of the iron core through a temperature measuring point on the iron core, and judging an abnormal temperature measuring point through generator temperature data. The inner interlayer temperature measuring points are grouped, every four temperature measuring points form one group, and the second round of time-space relation judgment is carried out, so that the turbine generator stator iron core end loosening fault is determined, a scientific evaluation result can be provided at the initial stage of the latent stator end loosening fault of the generator, meanwhile, a reasonable maintenance strategy is provided, and the reliability of the turbine generator stator iron core end loosening fault is improved. And safe ...

Application of gene promoter region sequence of glycerophospholipid peptidy transeferace in crop genetic improvement

The invention discloses a gene promoter region sequence of glycerophospholipid peptidy transeferace (LPAAT) and application in crop genetic improvement. The gene promoter region sequence of glycerophospholipid peptidy transeferace is shown as SEQ ID NO:1. The application method of the gene promoter of glycerophospholipid peptidy transeferace in crop genetic improvement comprises the following steps of: (1) inserting the gene promoter of glycerophospholipid peptidy transeferace into a promoter verifying expression vector pBI101.3 and starting the expression of a gus reporter gene; and (2) using the expression carrier for plant callus transgenosis research induced by agrobacterium tumefacien and obtaining the transgenosis plant by inducing, dip dyeing, coincubating and taking root of the plant callus. The gene promoter comes from coconut, can specially start expression of target gene in endosperm histiocyte, provides new promoter type in the future crop genetic improvement and has very high ...

Application of gene promoter region sequence of glycerophospholipid peptidy transeferace in crop genetic improvement

The invention discloses a gene promoter region sequence of glycerophospholipid peptidy transeferace (LPAAT) and application in crop genetic improvement. The gene promoter region sequence of glycerophospholipid peptidy transeferace is shown as SEQ ID NO:1. The application method of the gene promoter of glycerophospholipid peptidy transeferace in crop genetic improvement comprises the following steps of: (1) inserting the gene promoter of glycerophospholipid peptidy transeferace into a promoter verifying expression vector pBI101.3 and starting the expression of a gus reporter gene; and (2) using the expression carrier for plant callus transgenosis research induced by agrobacterium tumefacien and obtaining the transgenosis plant by inducing, dip dyeing, coincubating and taking root of the plant callus. The gene promoter comes from coconut, can specially start expression of target gene in endosperm histiocyte, provides new promoter type in the future crop genetic improvement and has very high ...

Supplementary sampling device of all -weather insulating oil

The utility model provides a supplementary sampling device of all -weather insulating oil, including the sample case, the inner chamber of sample case forms the sample space, and the sample case has and is used for sample space and the box that external environment separates, is equipped with the guide hole that the sample space was introduced to the sampling tube that is arranged in connecting thief hole inclusive AND thief hole on the corresponding electrical equipment on the box, be equipped with on the box to be arranged in supplying sample personnel staff to get into the sample space operating the line sewn down the back of a jacket that the sampling container was normally taken a sample, still be equipped with on the box and be used for supplying the sample personnel to observe the transparency region of the inside situation of sample space. The sample personnel hold the sampling container and carry out normal sampling operation at the sample space, like this owing to the box of sample ...

Feeding calibration method and system based on deep learning

The invention relates to a feeding calibration method based on deep learning. The method comprises the following steps: S1, installing an image shooting module at a feeding port; s2, downloading a feeding list, and obtaining batch information of feeding; s3, during feeding operation, the image shooting module is used for shooting the character information on the packaging bag of the material bag, and a shot image is obtained; s4, processing the shot image by using a deep learning technology to obtain batch information on the material package; and S5, matching the acquired batch information with the batch information in the feeding list, if the batch information is successfully matched with the batch information in the feeding list, prompting that the calibration is successful, otherwise, prompting that the calibration is wrong.

Portablely prevent electric reference test bar of maloperation type

The utility model relates to a portablely prevent electric reference test bar of maloperation type, hang the inconvenient problem of ground wire in the time of can effectively solving high -voltage testing wiring and high altitude construction, existing in a fixed tray, insulating putting in is equipped with along its long making progress down, the lower gliding insulating cover of, it has the fixed orifices to open on the lateral wall on the insulating cover down, go up on the lateral wall of insulating cover along long to equipartition some a plurality of and the corresponding regulation holes of fixed orifices, constitute the length adjustment structure of reassembling type, insulating cover lower extreme is provided with the cable interface down, the upper end of going up insulating cover is provided with the terminal, the both ends of test wire link to each other with cable interface and terminal respectively, the upper end of going up insulating cover is provided with the wiring gold ...

Ecological water level variation degree prediction method and system under coal seam mining in ecologically fragile area

The invention belongs to the technical field of green mines, and provides an ecological water level variation degree prediction method and system under coal seam mining in an ecologically fragile district, and the method comprises the steps: firstly determining the thickness of an effective overlying strata water-resisting layer after coal seam mining through the related data of mine engineering geological conditions, hydrogeological conditions and coal seam mining conditions of the ecologically fragile district; then, according to the thickness of an effective water-resisting layer of overlying strata after coal seam mining, three coal seam mining ecological diving leakage types are provided, and the leakage state of the coal seam mining ecological diving leakage types is determined; and finally, on the basis of establishing the well flow models in different ecological diving leakage states, calculating the ecological water level drop depth in the virtual water injection process, and realizing ...