Настройки

Укажите год
-

Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

Подробнее
-

Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

Подробнее

Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
Ведите корректный номера.
Ведите корректный номера.
Ведите корректный номера.
Ведите корректный номера.
Укажите год
Укажите год
Применить Всего найдено 15. Отображено 15.
23-09-2015 дата публикации

O,O-dialkyl-alpha-[3-bromo-1-(3-chloro-2-pyridyl)-1H-pyrazole-5-formyl]alkyl methylphosphonate derivative as well as preparation method and application thereof

Номер: CN104926871A
Автор: WANG WEI, WU ZONGKAI, HE QIWEN, LI BINGBO, ZHANG YUANYUAN, XU ZEGANG, WEI TIANQI, WEI LE, ZHANG JIANGONG, CHEN TAO, YANG CUIFENG, LIU KANGYUN, WANG LIEPING, LIN SHUANGZHENG, XUE CHAO, NING BINKE
Принадлежит:

The invention discloses an O,O-dialkyl-alpha-[3-bromo-1-(3-chloro-2-pyridyl)-1H-pyrazole-5-formyl]alkyl methylphosphonate derivative of which the general formula I is as shown in the description, wherein R represents a methyl group, an ethyl group, a propyl group or a butyl group; R<1> represents halogen, hydrogen, a methyl group or a methoxy group. The invention further discloses preparation methods of like compounds of the O,O-dialkyl-alpha-[3-bromo-1-(3-chloro-2-pyridyl)-1H-pyrazole-5-formyl]alkyl methylphosphonate derivative. The like compounds have remarkable inhibiting effects on three insecticide targets such as armyworms, aphids and red spiders, and can serve as efficient ingredients of an insecticide.

Подробнее
Номер записи: 1
18-11-2015 дата публикации

Device is left and taken to aseptic sample

Номер: CN0204765738U
Автор: REN MINGJIN, YANG CUIFENG, LIU JIA, HU LING, GUO JINYOU
Принадлежит:

The utility model discloses a device is left and taken to aseptic sample, including device body and the removable attraction head that sets up on device body top, center department is equipped with one and attracts the pipe in the device body, and the one end that attracts the pipe is equipped with the interface of connecting negative pressure generator, and the device body is including the filter chamber of leaving and taking the chamber with locating the hypomere of locating the upper segment, the filter chamber with leave and take the chamber zigzag connection and can separate each other, the filter chamber inner wall is equipped with a plurality of draw -in grooves, is equipped with an one -off filter screen in the draw -in groove at least. The zigzag connection that this device is left and taken to aseptic sample was equipped with can be separated the filter chamber each other and left and taken the chamber for it is separable to leave and take chamber and filter chamber, does benefit ...

Подробнее
Номер записи: 2
23-07-2014 дата публикации

Synthesis method of 4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide

Номер: CN103936678A
Автор: CHEN TAO, YANG CUIFENG, SU TIANDUO, NING BINKE, ZHANG JIANGONG, WANG LIEPING, LIN SHUANGZHENG, WANG YUEMEI
Принадлежит:

The invention discloses a synthesis method of 4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide (cyazofamid). According to the synthesis method, methylacetophenone is taken as a raw material, selenium dioxide is used for oxidation to prepare an intermediate, namely 2-carbonyl-2-p-benzyl aldehyde, then N,N-dimethylformamide and the like are taken as solvents, thionyl chloride is taken as a chlorinating agent and reducing agent for preparing the intermediate, and then intermediate further reacts with N,N-dimethyl sulfonamide chloride to synthesize the cyazofamid. Compared with the prior art, the synthesis method has the advantages that the reaction period is shortened, the post-treatment process is simplified and the synthesis method is suitable for mass industrial production.

Подробнее
Номер записи: 3
08-04-2015 дата публикации

Method for synthesizing alpha-amine formyl fluoroacetate compound

Номер: CN104496737A
Автор: WANG LUN, LIN SHUANGZHENG, LI BINGBO, WANG YUEMEI, YANG CUIFENG, WU ZONGKAI, WEI TIANQI
Принадлежит:

The invention discloses a method for synthesizing an alpha-amine formyl fluoroacetate compound. The method comprises the steps: performing reaction on a primary amino compound and fluoro-malonate which serve as raw materials under a solvent-free condition to prepare the alpha-amine formyl fluoroacetate compound; or performing reaction on a primary amine acid salt compound and the fluoro-malonic ester in the presence of a solvent and an acid-binding agent to prepare the alpha-amine formyl fluoroacetate compound. The method is easy to operate, quick in response and high in yield, can solve the problem that alpha-amine formyl fluoroacetate compound cannot be conveniently and quickly synthesized, and is suitable for easy preparation in a laboratory. The compound disclosed by the invention can be used for synthesizing fluorine-containing organic molecules.

Подробнее
Номер записи: 4
03-12-2014 дата публикации

Method for synthesizing chiral 3-amino-3-phenyl-2-hydroxy carboxylate compound

Номер: CN104177273A
Автор: YANG CUIFENG, LIN SHUANGZHENG, WANG YUEMEI, NING BINKE, WANG LUN, XU ZEGANG, WEI TIANQI, ZHANG YUANYUAN, LI BINGBO, WANG ANYONG, ZHANG XIAOGUANG
Принадлежит:

The invention discloses a method for synthesizing a chiral 3-amino-3-phenyl-2-hydroxy carboxylate compound. The method comprises the following steps: by taking nitrobenzyl and glyoxylate compounds as raw materials, reacting in an organic solvent under the catalysis of chiral organic alkali to prepare a 3-nitro-3-phenyl-2-hydroxy carboxylate compound, and performing reductive acylation to prepare the chiral 3-amino-3-phenyl-2-hydroxy carboxylate compound. According to the method disclosed by the invention, the raw materials are cheap and easily available, few steps are required for preparing the chiral 3-amino-3-phenyl-2-hydroxy carboxylate compound, and the final yield is high; the method is mainly applied to synthesis of a medical intermediate-chiral 3-amino-3-phenyl-2-hydroxy carboxylate compound.

Подробнее
Номер записи: 5
30-05-2023 дата публикации

Synthesis method of bixafen

Номер: CN116178264A
Автор: HUANG XIAOYING, WANG WEI, WANG LIEPING, MAO MINGZHEN, YANG CUIFENG, ZHENG XIAORUI
Принадлежит:

The invention discloses a synthesis method of bixafen, which comprises the following steps: 1, mixing magnesium powder and a solvent A, adding a solvent A solution of 3, 4-dichlorobromobenzene, and reacting to prepare a 3, 4-dichlorobenzene magnesium bromide metal compound; 2, the 3, 4-dichlorobenzene magnesium bromide metal compound is subjected to a metal transfer reaction through zinc chloride to prepare (3, 4-dichlorophenyl) zinc chloride, and the (3, 4-dichlorophenyl) zinc chloride, 2-bromine-4-fluoronitrobenzene, a catalyst and a solvent A are mixed for a reaction to obtain 2-(3, 4-dichlorophenyl)-4-fluoronitrobenzene; 3, 2-(3, 4-dichlorophenyl)-4-fluoronitrobenzene, iron powder, ammonium chloride, a solvent B and water are mixed, glacial acetic acid is added for a reaction, and 2-(3, 4-dichlorophenyl)-4-fluoroaniline is obtained; and step 4, mixing the 2-(3, 4-dichlorophenyl)-4-fluoroaniline with a solvent C, and adding a solution of the solvent C containing 1-methyl-3-difluoromethyl ...

Подробнее
Номер записи: 6
18-06-2014 дата публикации

Method for synthesizing compound 3-(3-amino furazan-4-yl)-4-hydroxy-1-oxygen-2, 4-diaza-spiran-2-alkene

Номер: CN103864712A
Автор: LIU NING, WANG BOZHOU, SHU YUANJIE, WANG WEI, YANG CUIFENG, GUO WANGJUN, ZHAI LIANJIE, HUANG XIAOWU
Принадлежит:

The invention discloses a method for synthesizing a compound 3-(3-amino furazan-4-yl)-4-hydroxy-1-oxygen-2, 4-diaza-spiran-2-alkene. The method comprises the following steps of adding 3-amino-4-dioxime furazan and an organic solvent into a reaction bottle while stirring at 20-25DEG C, then adding cyclohexanone, tetrahydro-4H-pyran-4-ketone, thiophane-3-ketone or 4-acetamino cyclohexanone, reacting for 30 minutes-12 hours while stirring at 0-40DEG C, after reaction, removing the organic solvent through evaporating, carrying out column chromatography isolation on the product so as to obtain the 3-(3-amino furazan-4-yl)-4-hydroxy-1-oxygen-2, 4-diaza-spiran-2-alkene, wherein the molar ratio of 3-amino-4-dioxime furazan to cyclic ketone is 1:(1-5), and the organic solvent is selected from methyl alcohol, ethyl alcohol or acetonitrile. The method is mainly used for synthesizing the compound 3-(3-amino furazan-4-yl)-4-hydroxy-1-oxygen-2, 4-diaza-spiran-2-alkene, the compound can be further synthesized ...

Подробнее
Номер записи: 7
22-04-2015 дата публикации

Method for synthesizing N,N'-bis-substituted fluoro malonamide compound

Номер: CN104529802A
Автор: WANG LUN, LIN SHUANGZHENG, WU ZONGKAI, WANG YUEMEI, YANG CUIFENG, LI BINGBO, WEI TIANQI
Принадлежит:

The invention discloses a method for synthesizing an N, N'-bis-substituted fluoro malonamide compound. The method comprises the following steps: carrying out reaction between primary amino-compounds and fluoro malonate which are used as raw materials under a solvent-free condition to prepare the N, N'-bis-substituted fluoro malonamide compound, or carrying out reaction between primary amine acidic salt compound and fluoro malonamide which are adopted as raw materials in the existence of solvent and acid-binding agent to prepare the N, N'-bis-substituted fluoro malonamide compound. The method is simple to operate, rapid in reaction and high in yield, the difficulty for simply and rapidly synthesizing the N,N'-bis-substituted fluoro malonamide compound can be solved, and the method is suitable for the simple preparation in a laboratory and also suitable for large-scale preparation. The prepared compound can be used for synthesizing fluorine-containing organic molecules.

Подробнее
Номер записи: 8
21-01-2015 дата публикации

Method for synthesizing 4-chloro-2-cyano-N,N-dimethyl-5-p-methylphenylimidazole-1-sulfamide

Номер: CN104292166A
Автор: WANG YUEMEI, LIN SHUANGZHENG, YANG CUIFENG, NING BINKE, XU ZEGANG, WANG LUN, LIU KANGYUN, LI BINGBO, WU ZONGKAI, WEI TIANQI, WANG ANYONG, ZHANG YUANYUAN
Принадлежит:

The invention discloses a method for synthesizing 4-chloro-2-cyano-N,N-dimethyl-5-p-methylphenylimidazole-1-sulfamide. The method is characterized in that 2-carbonyl-2-P-benzyl acetaldehyde is used as a raw material and reacted with glyoxylic acid to synthesize an imidazole ring, and then ammoniation, dehydration, chlorination and sulfonylation are performed, so that 4-chloro-2-cyano-N,N-dimethyl-5-p-methylphenylimidazole-1-sulfamide is finally synthesized. The purity of 4-chloro-2-cyano-N,N-dimethyl-5-p-methylphenylimidazole-1-sulfamide prepared by adopting the synthesizing method reaches over 98.0%, and the total yield reaches over 44.5%. The method is cheap and readily available in raw materials, simple, mild in reaction conditions and low in environmental pollution, and produces little wastewater. The method is mainly applied to synthesis of 4-chloro-2-cyano-N,N-dimethyl-5-p-methylphenylimidazole-1-sulfamide serving as a pesticide bactericide.

Подробнее
Номер записи: 9
10-09-2014 дата публикации

Method for synthesizing dichloroacetamidine

Номер: CN104030945A
Автор: YANG CUIFENG, WANG YUEMEI, LIN SHUANGZHENG, CHEN TAO, NING BINKE, ZHANG JIANGONG, XU ZEGANG
Принадлежит:

The invention discloses a method for synthesizing dichloroacetamidine. The method comprises the following step: reacting dichloroacetonitrile with liquid alcohol under the catalytic action of a small quantity of alkali carbonate to prepare dichloroacetamidine, wherein the molar ratio of alkali carbonate to dichloroacetonitrile is (0.05-0.1) to 1. According to the method, application of toxic gas-hydrogen chloride is avoided, and the consumption of hydrogen chloride is remarkably reduced in comparison with that of a sodium alcoholate base catalyst; the method is mainly applied to synthesis of a medial intermediate-dichloroacetamidine.

Подробнее
Номер записи: 10
12-11-2014 дата публикации

Method for recycling [(COD)IrCl]2

Номер: CN104140450A
Автор: WANG YUEMEI, LIN SHUANGZHENG, XU ZEGANG, NING BINKE, YANG CUIFENG, WEI TIANQI, ZHANG YUANYUAN
Принадлежит:

The invention discloses a method for recycling [(COD)IrCl]2. By the adoption of the method for recycling [(COD)IrCl]2, inactive [(COD)IrCl]2 or partially inactive [(COD)IrCl]2 is converted in hydrochloric acid, so that an iridium chloride mixture is obtained, the iridium chloride mixture and 1,5-cyclooctadiene react in an alcohol-water system, so that an active [(COD)IrCl]2 compound is obtained again. By the adoption of the method for recycling [(COD)IrCl]2, the utilization rate of the noble metal iridium can be increased, and the production cost can be effectively reduced; in addition, the operation process is simple, the recycling rate is high, and conditions are gentle. The method for recycling [(COD)IrCl]2 is suitable for recycling of iridium catalysis, wherein iridium is noble metal.

Подробнее
Номер записи: 11
07-01-2015 дата публикации

Method for synthesizing S-(+)-tetrahydrofuran-3-methanol

Номер: CN104262301A
Автор: WU ZONGKAI, LIN SHUANGZHENG, NING BINKE, HE QIWEN, YANG CUIFENG, WANG WEI, WANG LUN, WANG YUEMEI
Принадлежит:

The invention discloses a method for synthesizing S-(+)-tetrahydrofuran-3-methanol. The method comprises the following steps: reacting D (+)-10-camphorsulfonic acid with thionyl chloride, so as to obtain D-(+)-10-camphor sulfonyl chloride; reacting D-(+)-10-camphor sulfonyl chloride with (+/-)-tetrahydrofuran-3-methanol, so as to obtain tetrahydrofuran-3-methyl camphor sulphonate; standing tetrahydrofuran-3-methyl camphor sulphonate to crystallize, performing configuration inversion in the crystallization process, so as to obtain tetrahydrofuran-3-methyl camphor sulphonate of single configuration, dissociating the crystal by using a dissociation agent, so as to obtain S-(+)-tetrahydrofuran-3-methanol. By adopting the method, the phenomenon that only 50% of single configuration can be obtained in the chiral resolution process is avoided, the yield is greatly increased, the synthesis route is short, and the operation is simple. The method is mainly applied to synthesis of a midbody, namely ...

Подробнее
Номер записи: 12
25-03-2015 дата публикации

Sulfometuron methyl.fluazifop-p-butyl water dispersible granule

Номер: CN104430443A
Автор: WANG ANYONG, WANG LIEPING, WANG YUEMEI, WEI TIANQI, QIAN YISHI, LIU KANGYUN, YANG CUIFENG, NING BINKE, XUE CHAO, SUN QIAONAN, ZHANG XIAOGUANG, LI BINGBO
Принадлежит:

The invention discloses a sulfometuron methyl.fluazifop-p-butyl water dispersible granule. The preparation comprises sulfometuron methyl, fluazifop-p-butyl, a wetting agent, a dispersing agent, a disintegrating agent, a binder and a filler, wherein the mass percent of each component to the water dispersible granule is as follows: 1-90% of sulfometuron methyl, 1-50% of fluazifop-p-butyl, 1-10% of the wetting agent, 1-10% of the dispersing agent, 1-8% of the disintegrating agent, 0-5% of the binder and the balance of the filler. According to the sulfometuron methyl.fluazifop-p-butyl water dispersible granule, when the herbicidal activities of sulfometuron methyl and fluazifop-p-butyl are not changed, sulfometuron methyl and fluazifop-p-butyl are compounded according to a reasonable proportion, and auxiliaries and the filler are added to prepare the water dispersible granule, so that a synergy purpose is achieved; the compounded preparation is used for controlling un-cultivated-area weeds, ...

Подробнее
Номер записи: 13
30-05-2023 дата публикации

Method for synthesizing N-aryl ketimine through acid catalysis ketalation method and application of N-aryl ketimine

Номер: CN116178336A
Автор: SONG PEIDONG, XU ZEGANG, YANG CUIFENG, RONG HAOJIE
Принадлежит:

The invention discloses a method for synthesizing N-aryl ketimine by an acid catalysis ketal method and application, the method takes lewis acid or organic acid as a catalyst, and under a heating condition, arylamine and ketal are condensed to generate the N-aryl ketimine. The method has the advantage that the method still has an excellent reaction effect for condensation reaction of arylamine and alkyl ketone with poor nucleophilicity caused by electrical property or steric hindrance. The method is simple to operate, high in raw material conversion rate, good in reaction selectivity, high in product yield and good in product quality. The method can be applied to efficient synthesis of a herbicide dimethenamid.

Подробнее
Номер записи: 14
03-06-2015 дата публикации

Continuous preparation method of 1-acetyl-1-chlorocyclopropane

Номер: CN104672074A
Автор: ZHANG XIAOGUANG, NING BINKE, LI BINGBO, LIN SHUANGZHENG, MAO MINGZHEN, XU ZEGANG, YANG CUIFENG, ZHANG YUANYUAN, ZHANG JIANGONG, HUANG XIAOYING, HE QIWEN
Принадлежит:

The invention discloses a continuous preparation method of 1-acetyl-1-chlorocyclopropane. A tubular reactor is applied to the preparation process of the 1-acetyl-1-chlorocyclopropane, and the tubular reactor, a solid-liquid feeding pump, a film evaporator and matched equipment are adopted. The continuous preparation method is superior to methods in the prior art and comprises steps as follows: 3,5-dichloro-2-pentanone, a solvent and an alkali are fully mixed and react in the tubular reactor, a reaction liquid is transferred out of the tubular reactor timely and transferred into the film evaporator synchronously to be separated, and a qualified product is obtained. The method has the benefits as follows: the retention time of the product in the reaction liquid is short, so that deterioration is avoided; the continuous preparation method of the 1-acetyl-1-chlorocyclopropane is realized, the production efficiency and the yield are high, and the operation is convenient.

Подробнее
Номер записи: 15