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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 4. Отображено 4.
27-06-2023 дата публикации

Improved reprogramming, maintenance and preservation of induced pluripotent stem cells

Номер: CN116348592A
Автор: LAI YIXIN, WALAMAR BERND, ABJARUL RAJALESH, XU HUITING
Принадлежит:

Methods and compositions are provided for inducing reprogramming of non-pluripotent cells using small molecule supported vector systems to efficiently provide iPSCs with desired characteristics. Also provided are reprogramming of cells and populations of iPSC or cloned cell lines using the provided reprogramming methods and compositions. Further provided are compositions and methods for maintaining and preserving the iPSC while achieving genomic stability of the cell.

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Номер записи: 1
09-05-2023 дата публикации

Combining iPSC-derived effector cell types for use in immunotherapy

Номер: CN116096386A
Автор: WALAMAR BERND, GOODRICH JASON, BJORDAHL RUNE
Принадлежит:

The present invention provides methods and compositions for obtaining functionally enhanced derived effector cells obtained by directed differentiation of genome engineered iPSCs. The derived cells provided herein have stable and functional genome editing that delivers improved or enhanced therapeutic effects. Also provided are therapeutic compositions and uses thereof comprising the functionally enhanced derived effector cells alone or in combination therapy with antibodies or checkpoint inhibitors or appendage cells.

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Номер записи: 2
18-07-2023 дата публикации

Engineered iPSC and armed immune effector cells

Номер: CN116457367A
Автор: PERATA ELENA, WALAMAR BERND, LYU DAN, LI TONG, WITTY AARON
Принадлежит:

The present invention provides methods and compositions for obtaining functionally enhanced derived effector cells obtained by directed differentiation of genome engineered iPSCs. The iPSC-derived cells provided herein have stable and functional genome editing that delivers improved or enhanced therapeutic effects. Also provided are therapeutic compositions and uses thereof comprising the functionally enhanced derived effector cells alone or in combination therapy with an antibody or checkpoint inhibitor.

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Номер записи: 3
07-07-2023 дата публикации

Engineered iPSC and persistent immune effector cells

Номер: CN116406373A
Автор: WALAMAR BERND, PERATA ELENA, ZHANG JIAWEI
Принадлежит:

The present invention provides methods and compositions for obtaining functionally enhanced derived effector cells obtained by directed differentiation of genome engineered iPSCs. The iPSC-derived cells provided herein have stable and functional genome editing that delivers improved or enhanced therapeutic effects. Also provided are therapeutic compositions and uses thereof comprising the functionally enhanced derived effector cells alone or in combination therapy with an antibody or checkpoint inhibitor.

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Номер записи: 4