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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 8. Отображено 8.
06-02-2017 дата публикации

COMPOSITION FOR PREVENTING OR TREATING CANCER

Номер: KR101702468B1
Автор: PARK, JONG SUN, PARK, JI SOO, KIM, SUN HWAN, TRAN QUANG DON
Принадлежит: THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC)

The present invention relates to a pharmaceutical composition comprising benzene propane nitrile, 4-methoxy-α-[2-(2-methylphenyl)hydrazinylidene]-β-oxo-, or pharmaceutically acceptable salt thereof as an active component for preventing or treating cancer. According to the present invention, benzene propane nitrile, 4-methoxy-α-[2-(2-methylphenyl)hydrazinylidene]-β-oxo-, or pharmaceutically acceptable salt thereof induces autophagocytosis of cancer cells specific to mitochondria and, as a result, causes apoptosis of cancer cells. COPYRIGHT KIPO 2017 ...

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Номер записи: 1
11-07-2016 дата публикации

COMPOSITION FOR PREVENTING AND TREATING CANCER

Номер: KR101638567B1
Автор: PARK, JONG SUN, PARK, JI SOO, KIM, SUN HWAN, TRAN QUANG DON
Принадлежит: THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC)

The present invention relates to a composition for preventing or treating cancers, comprising 2-furanopropanenitrile, alpha-[2-[3,5-bis(trifluoromethyl)phenyl]hydrazinylidene]-beta-oxo-, or pharmaceutically acceptable salts thereof as active ingredients. According to the present invention, the 2-furanopropanenitrile, the alpha-[2-[3,5-bis(trifluoromethyl)phenyl]hydrazinylidene]-beta-oxo-, or the pharmaceutically acceptable salts thereof can occur cancer cell death by inducing mitochondria specific autophagy of cancer cells. COPYRIGHT KIPO 2016 ...

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Номер записи: 2
19-09-2018 дата публикации

COMPOSITION FOR PREVENTION OR TREATMENT OF DISEASES OCCURRED BY AUTOPHAGY DISORDER IN MITOCHONDRIA, COMPRISING EXPRESSION INHIBITORS OF S6K1 GENES OR ACTIVITY INHIBITORS OF S6K1 PROTEIN

Номер: KR1020180103442A
Автор: PARK, JONG SUN, PARK, JI SOO, KIM, SEON HWAN, LEE, HYUN JI, TRAN QUANG DON
Принадлежит:

The present invention relates to a composition for the prevention or treatment of diseases occurred by the autophagy disorder in mitochondria, comprising expression inhibitors of S6K1 genes or activity inhibitors of S6K1 protein as an effective component. The composition has an excellent effect on controlling autophagy in mitochondria, thereby having an effect of treating or alleviating cervical cancer, lung cancer, gastric cancer, etc. which are diseases caused by the autophagy in mitochondria. Thus the composition can be variously utilized as medicines, health functional food, etc. COPYRIGHT KIPO 2018 ...

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Номер записи: 3
25-10-2017 дата публикации

ANIMAL MODEL HAVING OBESITY AND USES THEREOF

Номер: KR1020170118315A
Автор: PARK, JONG SUN, PARK, JI SOO, KIM, SEON HWAN, LEE, HYUN JI, KIM, DO HOON, TRAN QUANG DON, HONG, YOUNG EUN
Принадлежит:

The present invention relates to an animal model having obesity and to uses thereof, and specifically, to a method for manufacturing an animal model having obesity comprising a step for injecting a vector containing a PHF 20 gene to an animal, to an over-expressed animal model having obesity, and to a method for screening a material for preventing or treating diabetes using the same. The animal model having obesity according to the present invention has increased body weight, volume, lipid accumulation, energy absorption and mitochondrial biosynthesis in adipose tissue to be usefully used in studies on the pathogenesis of diseases caused by obesity, screening of obesity therapeutic agents, development of new drugs, and the like. COPYRIGHT KIPO 2017 (AA) Wild type (BB) Obese animal model ...

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Номер записи: 4
13-09-2016 дата публикации

COMPOSITION FOR PREVENTING AND TREATING CANCER

Номер: KR101656663B1
Автор: PARK, JONG SUN, PARK, JI SOO, KIM, SUN HWAN, TRAN QUANG DON
Принадлежит: THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC)

The present invention relates to a pharmaceutical composition for preventing or treating cancer, comprising (E)-1-(4-chlorophenyl)-2-cyanoguadinine or pharmaceutically acceptable salt thereof as an active ingredient. According to the present invention, the (E)-1-(4-chlorophenyl)-2-cyanoguadinine or pharmaceutically acceptable salt thereof can consequently generate the death of cancer cells by inducing mitochondria-specific autophagy of cancer cells. COPYRIGHT KIPO 2016 ...

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Номер записи: 5
06-02-2017 дата публикации

COMPOSITION FOR PREVENTING AND TREATING CANCER

Номер: KR101702464B1
Автор: PARK, JONG SUN, PARK, JI SOO, KIM, SUN HWAN, TRAN QUANG DON
Принадлежит: THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC)

The present invention relates to a pharmaceutical composition comprising 2-[(3-chlorophenyl)hydrazonol-3-oxo-3-phenylpropane nitrile or pharmaceutically acceptable salt thereof as an active component for preventing or treating cancer. According to the present invention, the 2-[(3-chlorophenyl)hydrazonol-3-oxo-3-phenylpropane nitrile or pharmaceutically acceptable salt thereof induces autophagocytosis of cancer cells specific to mitochondria and, as a result, causes apoptosis of cancer cells. COPYRIGHT KIPO 2017 ...

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Номер записи: 6
30-10-2017 дата публикации

CANCER DIAGNOSIS COMPOSITION CONTAINING TMEM39A GENE

Номер: KR1020170119888A
Автор: PARK, JONG SUN, PARK, JI SOO, KIM, SEON HWAN, LEE, HYUN JI, KIM, DO HOON, TRAN QUANG DON, HONG, YOUNG EUN
Принадлежит:

The present invention relates to a transmembrane protein 39A (TMEM39A) gene, and a use thereof. According to the present invention, by providing a detection preparation for TMEM39A as a marker for diagnosing cancer, especially brain tumor, it is possible to grasp and predict the degree of disease and also to diagnose development of the disease, by comparing and measuring the level of expression of the gene or a protein thereof in a patient, thereby being useful for managing prognosis and treating cancer, especially brain tumor. COPYRIGHT KIPO 2017 ...

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Номер записи: 7
29-09-2017 дата публикации

METHOD FOR PROVIDING INFORMATION ON CANCER CELLS USING PHF 20 (PHD FINGER PROTEIN 20)

Номер: KR1020170109340A
Автор: PARK, JONG SUN, PARK, JI SOO, KIM, SEON HWAN, LEE, HYUN JI, KIM, DO HOON, TRAN QUANG DON, HONG, YOUNG EUN
Принадлежит:

The present invention relates to a method for providing information on cancer cells associated with regulation of saccharometabolism in cancer cells, involving a use of a detection preparation for PHF 20 (PHD finger protein 20). The present invention further relates to a kit thereby. In an attempt to conduct investigation and diagnosis on cancer cells, it is possible to provide information on an increase in saccharification-dependant ATP productivity, reduction in the total antioxidant functions, an increase in angiogenesis, and an increase in biosynthesis of mitochondria in cancer cells by targeting PHF20. Thus, the method of the present invention can be useful for developing treatment agents and diagnosing cancer. COPYRIGHT KIPO 2017 ...

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Номер записи: 8