Настройки

Укажите год
-

Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

Подробнее
-

Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

Подробнее

Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
Ведите корректный номера.
Ведите корректный номера.
Ведите корректный номера.
Ведите корректный номера.
Укажите год
Укажите год
Применить Всего найдено 37. Отображено 37.
21-07-2023 дата публикации

Hydrophobic cellulose as well as preparation method and application thereof

Номер: CN116463851A
Автор: ZHENG MINGMING, LIU TIELIANG, SHEN YUNFEI, SHEN JIAYUAN, ZHANG YIXUAN, ZHANG YUFEI
Принадлежит:

The invention belongs to the technical field of preparation and application of new materials, and discloses hydrophobic cellulose as well as a preparation method and application thereof. The preparation method comprises the following steps: firstly, adding long-chain fatty acid, fatty acid anhydride or fatty acid acyl chloride serving as an esterifying agent and a catalyst into a solvent to prepare a hydrophobic modified solution; secondly, carrying out wet modification or semi-dry modification on the cellulose by adopting a hydrophobic modification solution; and finally, cleaning the modified cellulose with hot water spray, and drying to obtain the hydrophobic cellulose. The cellulose is subjected to hydrophobic functional modification by using long-chain fatty acid, fatty acid anhydride or fatty acid acyl chloride, a semi-dry modification method is created, the process route is simple, the conditions are mild, the method is green and environment-friendly, and the obtained hydrophobic ...

Подробнее
Номер записи: 1
16-12-2015 дата публикации

Can dismantle operating room terrestrial system

Номер: CN0204876462U
Автор: LU JIANNAN, FENG YIXIN, LIU LINXIAN, JIANG ZHIXING, YU JINGLIANG, SHEN YUNFEI
Принадлежит:

The utility model relates to a can dismantle operating room terrestrial system, can dismantle operating room terrestrial system comprises the concatenation of a plurality of ground unit, the ground unit includes outside sheet layer, inner face sheet layer and base, the inner face sheet layer is located the top of base, and the upper surface of inner face sheet layer is provided with a plurality of micropores that do not pierce through the inner face sheet layer, the micropore that the outside sheet layer passes through inner face sheet layer upper surface adsorbs in the upper surface of inner face sheet layer. All ground units of this can dismantle operating room terrestrial system are in to complete the processing of of processing factory and equipment, and the quality of ground unit is controllable. Only need splice the ground unit in order at the construction field (site), the efficiency of construction is high. In addition, the pressure differential that produces through the micropore ...

Подробнее
Номер записи: 2
08-09-2010 дата публикации

Balsm-pear-seed ribosome inactivated protein and its coding gene and use

Номер: CN0101070342B
Автор: SHEN YUNFEI, ZHOU MANXIANG, SUN HONGYAN, YUNFEI SHEN, MANXIANG ZHOU, HONGYAN SUN
Принадлежит:

This invention relates to a balsam pear seed ribosome inactivating protein(RIP) and its encode gene and application. This protein has one of the undermentioned amino acid residue sequence: (1) SEQ ID NO:1 in the sequence table; (2) carry out substitution, deficiency or addition of protein that possess activity of inhibiting ribosomal protein synthesis to one to ten amino acid residue of SEQ ID NO: 1 amino acid residue sequence in sequence table. This protein possess hereinafter point: (1) notable effect of resisting tumour and virus infection; (2) high security; (3) simple protein expression condition, easy purification. low cost.

Подробнее
Номер записи: 3
18-05-2011 дата публикации

Methylovorus sp. MP688 and application thereof

Номер: CN0102061278A
Автор: JIANHUA WANG, WEICAI ZHANG, XIANGHUA XIONG, JINGJUAN ZHI, LU YANG, YANXIN YANG, XIN WANG, MIAOXIN LI, YANJU CUI, FANG DONG, BAOHUA DU, MANXIANG ZHOU, LIN WEI, YUNFEI SHEN, YUE LI, HONGYU WEI, WANG JIANHUA, ZHANG WEICAI, XIONG XIANGHUA, ZHI JINGJUAN, YANG LU, YANG YANXIN, WANG XIN, LI MIAOXIN, CUI YANJU, DONG FANG, DU BAOHUA, ZHOU MANXIANG, WEI LIN, SHEN YUNFEI, LI YUE, WEI HONGYU
Принадлежит:

The invention discloses a new strain MP688 of Methylovorus sp., of which the preservation number is CGMCC No.4096, the preservation date is August 20th, 2010, and the preservation unit is China General Microbiological Culture Collection Center. The strain MP688 is separated from soil by using a GDH (glutamate dehydrogenase) recombinase method of PQQ (pyrroloquinoline quinone). By using the Methylovorus sp. strain disclosed by the invention, the yield of PQQ can reach 125 mg/L in a conventional culture medium under conventional culture conditions; and the Methylovorus sp. strain can be used for industrial production of PQQ, and has important meaning for promoting the industrialization of PQQ.

Подробнее
Номер записи: 4
28-04-2023 дата публикации

Intelligent production line for wheel nuts and production process

Номер: CN116020760A
Автор: SHEN YUNFEI, GU HONGMING, DU QINGHE
Принадлежит:

The invention relates to the technical field of production and conveying, in particular to an intelligent production line for wheel nuts and a production process. The invention provides an intelligent production line for wheel nuts. A conveying line is suitable for conveying workpieces. The detecting and screening part is fixed to one side of the operation table, the feeding end of the detecting and screening part communicates with the conveying line, and the discharging end of the detecting and screening part faces the operation table. After the workpieces on the conveying line move and enter the detecting and screening part, the movable end of the detecting and screening part rotates in the circumferential direction to turn over the workpieces, so that the workpieces are discharged out of the detecting and screening part with the front faces facing upwards. The movable end of the detecting and screening part is suitable for detecting whether the workpieces are qualified or not, and unqualified ...

Подробнее
Номер записи: 5
23-06-2023 дата публикации

Downlink synchronization state machine for optical line terminal (OLT) configurable bit interleaving in high speed passive optical networks (PONs)

Номер: CN116325574A
Автор: LIU XIANG, SHEN YUNFEI, EFFENBERGER FRANK, LUO YUANQIU
Принадлежит:

A method implemented by an optical network unit (ONU) in a passive optical network (PON). The method includes: receiving an encoded downlink (DS) signal from an optical line terminal (OLT); searching a physical synchronization sequence (PSync) pattern in all possible alignments in the downlink signal for all possible OLT bit interleaving modes; and upon finding the PSync pattern, transitioning to a pre-synchronization state.

Подробнее
Номер записи: 6
13-10-2010 дата публикации

Fusion protein with function of selective killing endothelial cells in tumor neogenetic blood vessels and use thereof

Номер: CN0101070349B
Автор: ZHOU MANXIANG, SUN HONGYAN, SHEN YUNFEI, MANXIANG ZHOU, HONGYAN SUN, YUNFEI SHEN
Принадлежит:

This invention relates to a fusion protein that possess action of selectively kill tumour rebirth blood vessel endotheliocyte, and its application. This fusion protein through connecting peptide connect VEGF121 with amido end of sponge gourd seed ribosome inactivating protein(RIP) Luffin Alpha. The vascular endothelial cell growth factor VEGF121 act as means of delivery, make this fusion toxin idiosyncratic incorporate with vascular endothelial cell growth factor receptor F1k1/ KDR, thereby optionally ingress tumour rebirth vascular endothelial cell; the polypeptide possess amphipathic molecule character, by destroy lysosome membrane to promote the release of lysosome inside dissociate toxin molecule; the toxin carboxyl terminal endoplasmic reticulum loacting signal led toxin molecule( sponge gourd seed RIP Luffin Alpha) to target site to exert toxic effect, so to destroy rebirth blood vessel of tumour organization, cut off tumour blood supply, achieve the end of restraining tumor.

Подробнее
Номер записи: 7
23-12-2009 дата публикации

Technique for producing stearate by dry method and device

Номер: CN0101607882A
Автор: SHEN YUNFEI, LUO MINGZHUANG, YUNFEI SHEN, MINGZHUANG LUO
Принадлежит:

The invention discloses a technique for producing stearate by a dry method. The technique comprises the following steps of: adding stearate, metal compound and water with the proportion of 82 to 88%:10 to 15%:2 to 5% into a reactor, stirring and reacting for 1 to 5 hours with the temperature of 50 to 150 DEG C and pressure of 0 to 0.10 MPa, and then obtaining the stearate. The reaction device is characterized in that a motor (1) is connected with a speed reducer (2) which is connected with a gear transmission (3); the gear transmission (3) is connected with a stirrer (9) arranged in a reaction container (4); and a feeding port (6) is arranged above the reaction container (4) which is externally provided with a clamping sleeve (8), and a discharging port (10) is arranged below the reaction container (4). The invention simplifies operation steps, lowers the cost and energy consumption, reduces the discharging volume of wastewater, decreases pollution-controlling cost, further reduces the ...

Подробнее
Номер записи: 8
20-02-2008 дата публикации

Composite sweetener containing trichlorosucrose and preparation method thereof

Номер: CN0101124960A
Автор: GUOHUA HU, ZHENGZHI MA, HUI LI, YUNFEI SHEN, HU GUOHUA, MA ZHENGZHI, LI HUI, SHEN YUNFEI
Принадлежит:

The present invention relates to a compound sweetening agent that contains trichloro cane sugar. The main ingredient of the present invention is trichloro cane sugar which is a novel high power sweetening agent and which contributes to the main part of sugariness. The trichloro cane sugar is then supermicrocrushed together with high power sweetening agent, such as saccharin sodium and Aspartame before being blended with a carrier to produce a novel compound sweetening agent. The carrier of the invention is dextrine which compensates the sweetness, wherein, the quantity percentages of the trichloro cane sugar, the saccharin sodium, the Aspartame and the dexitrine are 10 percent to 15 percent, 5 percent to 10 percent, 5 percent to 15 percent and 60 to 75 percent respectively. The compound sweetening agent is formulated through science and has the advantages of special favor, sugar-free, low cost and wide market prospects.

Подробнее
Номер записи: 9
07-09-2011 дата публикации

Preparation and use of recombinant mtVEGF121/MAP30KDEL fusion noxioussubstance

Номер: CN0101434657B
Автор: ZHOU MANXIANG, SUN HONGYAN, SHEN YUNFEI, MANXIANG ZHOU, HONGYAN SUN, YUNFEI SHEN
Принадлежит:

The present invention discloses a fusion toxin with the effect of selectively killing neovasculature endothelial cells and an application thereof. The fusion toxin is obtained from connecting mtVEGF121 by connecting peptide at the amino terminal of ribosome-inactivating protein of a bitter melon seed. The mtVEGF121, which is taken as a carrier, causes that the fusion toxin is specifically bonded with a growth factor receptor F1k1/KDR of a vasculature endothelial cell and internalized to enter the vasculature endothelial cell and then the toxic effect of MAP30 is exerted to kill the neovasculature endothelial cell and further damage neovasculature. The fusion toxin is simple in expression condition, easy to be purified and liable to be produced in large scale; therefore, the fusion toxin can be taken as an active component for preparing medicaments for resisting a plurality of diseases related to neovasculature enhancement, such as cancer, fundus oculi angiogenesis during late-stage diabetes ...

Подробнее
Номер записи: 10
14-07-2023 дата публикации

Geological disaster induced landslide monitoring device and monitoring method

Номер: CN116428989A
Автор: MIYAOKA, SHEN YUNFEI, MA KAIQIANG, LI JINXIANG
Принадлежит:

The invention discloses a geological disaster induced landslide monitoring device and monitoring method, and belongs to the technical field of disaster prevention and monitoring. A geological disaster induced landslide monitoring device comprises a base and a monitor, and further comprises a mounting column fixedly connected to the top of the base, and a water receiving tank fixedly connected to the top of the mounting column; the mounting box is fixedly connected to the side wall of the mounting column, and a glass cover is rotationally connected to the bottom of the mounting box; rainwater is received, the glass cover is cleaned through the rainwater, the surface of the glass cover is kept clean, the situation that the detection precision is reduced due to blurred vision is avoided, sunlight is gathered through the reflector, water is boiled to generate water vapor, the water vapor is discharged into cold water in the water receiving tank, the temperature of the water is neutralized, ...

Подробнее
Номер записи: 11
07-04-2023 дата публикации

Radar detection system, method and equipment based on vehicle parking and storage medium

Номер: CN115932740A
Автор: SHEN YUNFEI, TIAN YUAN, HE YUE, CHEN SIXIANG
Принадлежит:

The invention provides a radar detection system, method and equipment based on vehicle parking and a storage medium, and the system comprises a radar antenna device which is used for setting the beam width in the horizontal direction and the beam width in the vertical direction of the radar antenna device, and transmitting a local oscillator signal, receiving an echo signal reflected by the local oscillator signal after the target is detected; the signal processing module is used for setting the angle resolution and the distance resolution of the radar antenna device; and the data processing module is used for detecting a target state in combination with the local oscillator signal and the echo signal. According to the radar detection system provided by the invention, the detection precision and resolution can still be ensured when a distance far enough is detected.

Подробнее
Номер записи: 12
30-10-2020 дата публикации

Suspended ceiling safety fixing structure assembly

Номер: CN0211817335U
Автор: SHEN YUNFEI
Принадлежит: JIAXING LENBOND ELECTRICAL TECH CO LTD, JIAXING LENBOND ELECTRICAL TECHNOLOGY CO., LTD.

The utility model provides a suspended ceiling safety fixing structure assembly, and belongs to the technical field of suspended ceiling accessories. The suspended ceiling structure comprises a triangular keel and a suspended ceiling arranged in the triangular keel in a sleeved mode. A lock catch assembly is further arranged between the triangular keel and the suspended ceiling. The lock catch assembly comprises a safety buckle body connected with a suspended ceiling, the bottom of the safety buckle body is movably connected with a rotating buckle piece capable of rotating in the circumferential direction, the end, away from the safety buckle body, of the rotating buckle piece is connected with the triangular keel, and the safety buckle body is further connected with a bolt which sequentially penetrates through the safety buckle body and the rotating buckle piece from top to bottom and is provided with threads. The end, away from the rotary fastener, of the safety buckle body is fixedto ...

Подробнее
Номер записи: 13
23-12-2009 дата публикации

Dry production technique and device of calcium stearate

Номер: CN0101607881A
Автор: SHEN YUNFEI, LUO MINGZHUANG, YUNFEI SHEN, MINGZHUANG LUO
Принадлежит:

The invention discloses a dry production technique of calcium stearate, which comprises the following steps of: adding stearic acid, calcium compound and water in a reacting device according to the weight ratio of 82-88 percent to 10-15 percent to 2-5 percent, and stirring at the temperature of 80 to 150 DEG C under the pressure of 0 to 0.10 MPa for reaction for 1 to 5 hours, thus obtaining the calcium stearate. The reacting device is characterized in that a motor (1) is connected with a speed reducer (2), and the speed reducer (2) is connected with a gear transmission (3); the gear transmission (3) is connected with a stirrer (9) arranged in a reactor (4); a temperature detecting port (5) and a feeding port (6) are arranged above the reactor (4); a clamping sleeve (8) is arranged outside the reactor (4); and a discharge hole (10) is arranged below the reactor (4). The technique simplifies the operation procedures, reduces cost and energy consumption, reduces discharge of waste water, lowers ...

Подробнее
Номер записи: 14
23-12-2009 дата публикации

Technique for producing zinc stearate by dry method and device

Номер: CN0101607883A
Автор: SHEN YUNFEI, LUO MINGZHUANG, YUNFEI SHEN, MINGZHUANG LUO
Принадлежит:

The invention discloses a technique for producing zinc stearate by a dry method. The technique comprises the following steps of: adding stearate, zinc compound and water in a mass ratio of 82 to 88%:10 to 15%:2 to 5% into a reactor, stirring and reacting for 1 to 5 hours at temperature of 50 to 150 DEG C and pressure of 0 to 0.10 MPa, and then obtaining the zinc stearate. The reaction device is characterized in that a motor (1) is connected with a speed reducer (2) which is connected with a gear transmission (3); the gear transmission (3) is connected with a stirrer (9) arranged in a reaction container (4); and a temperature measuring port (5) and a feeding port (6) are arranged above the reaction container (4) which is externally provided with a clamping sleeve (8), and a discharging port (10) is arranged below the reaction container (4). The invention has simple technique, little equipment investment, short production period, no wastewater discharging, high efficiency and low cost; and ...

Подробнее
Номер записи: 15
26-01-2011 дата публикации

Felodipine sustained-release tablets and preparation method thereof

Номер: CN0101953837A
Автор: MANXIANG ZHOU, YUNFEI SHEN, XUEWEN QIAO, HUILAN ZHANG, ZHOU MANXIANG, SHEN YUNFEI, QIAO XUEWEN, ZHANG HUILAN
Принадлежит:

The invention belongs to the technical field of medicament preparation, and particularly relates to felodipine sustained-release tablets for treating hypertension and a preparation method thereof. The invention aims to solve the technical problems of high oxide content, unstable quality and unsteady dosage release of the conventional felodipine sustained-release tablets. The felodipine sustained-release tablets are prepared from the following components: felodipine cyclodextrin clathrate compound, framework sustained-release material, retardant, filling agent, microcrystalline cellulose, lubricant and flow aid, wherein the components are mixed together to prepare tablet cores, and then the tablet cores are coated by Opadry coating powder. The preparation method specifically comprises the following steps of: firstly, preparing the felodipine cyclodextrin clathrate compound from a cyclodextrin material and felodipine; secondly, preparing the tablet cores from the felodipine cyclodextrin clathrate ...

Подробнее
Номер записи: 16
05-01-2011 дата публикации

Glucosamine potassium sulfate microcapsule and preparation method and application thereof

Номер: CN0101606922B
Автор: ZHOU MANXIANG, SHEN YUNFEI, ZHANG HUILAN, MANXIANG ZHOU, YUNFEI SHEN, HUILAN ZHANG
Принадлежит:

A glucosamine potassium sulfate microcapsule comprises 15-75% of glucosamine potassium sulfate used as active constituent and other necessary accessories. The preparation method of the glucosamine potassium sulfate microcapsule comprises the following steps: dissolving hydroxypropylmethyl cellulose in 90% of ethanol solution to prepare a 1-10% of solution, then adding plasticizer, antisticking agent and glucosamine potassium sulfate which has the dose corresponding the required dose of the active constituent with a particle size of 150 microns or less than 150 microns, to prepare even suspension and finally obtaining glucosamine potassium sulfate microcapsule through spray drying. The invention coats a macromoleclar polymer film outside the glucosamine potassium sulfate, guarantees the stability of product quality, avoids the absorption of moisture and oxidation of the products and benefits the product storage.

Подробнее
Номер записи: 17
04-07-2012 дата публикации

Device for deeply dewatering, drying and pyrolyzing sludge at low temperature

Номер: CN0102211844B
Автор: PANSHENG QIAN, YUNFEI SHEN, QIAN PANSHENG, SHEN YUNFEI
Принадлежит:

The invention discloses a device for deeply dewatering, drying and pyrolyzing sludge at low temperature, which is characterized by comprising a storage bin (1), a dewatering machine (2), a sludge mixer (3) and a sludge dryer (4) which are connected in sequence. An outlet of the sludge dryer (4) is connected with an inlet of a sludge low-temperature pyrolyzing furnace (5). A cinder outlet of the sludge low-temperature pyrolyzing furnace (5) is connected with a melting device (7). A liquid phase outlet and a gas phase outlet of the sludge low-temperature pyrolyzing furnace (5) are respectively connected with a fluidized combustion furnace (10) and a gas separation film (6). After being connected with the gas separation film (6), the gas phase outlet of the sludge low-temperature pyrolyzing furnace (5) is connected to the fluidized combustion furnace (10). The device disclosed by the invention has the advantages of simple process, compact and practical equipment and high heat energy utilization ...

Подробнее
Номер записи: 18
15-08-2023 дата публикации

Optimization method and device for data classification query in overload scene

Номер: CN116595040A
Автор: YE FEI, YANG ZHIHUI, SHEN YUNFEI, HE ZHENYING, JING YINAN, ZHANG KAI, WANG XIAOYANG
Принадлежит:

The invention discloses an optimization method and device for data classification query in an overload scene. A query result of a stream data overload scene is optimized by improving a query process. The invention provides an online training mode which comprises a series of probability filters, the probability filters are mainly used for screening data (such as text data) based on semantic information contained in queries, the optimal configuration of the filters is obtained in a parameter search mode, and meanwhile, the delay of the queries is controlled by a function fitting method. The method focuses on processing queries including data classification tasks in a streaming data scene, and aims at solving the query optimization problem in a streaming data overload scene. Compared with query optimization work based on an off-line scene, the method has the advantages that the query time is not limited, and a good optimization effect is achieved when the query time limit is given and the ...

Подробнее
Номер записи: 19
11-07-2023 дата публикации

Sandwich composite material, preparation method and application thereof, and preparation method of aqueous zinc ion battery negative electrode

Номер: CN116417601A
Автор: CHEN LONG, SHEN YUNFEI, MIN JUN, LI SHANSHAN, YAO LIANSHENG, MA XIAOJUN, MU FULAN
Принадлежит:

The invention relates to the technical field of water-based zinc ion batteries, in particular to a sandwich composite material, a preparation method and application thereof and a preparation method of a water-based zinc ion battery negative electrode. The invention provides a preparation method of a sandwich composite material, which comprises the following steps: mixing MAX, sodium chloride and copper chloride, and carrying out heat treatment to obtain an intermediate product; and sequentially carrying out cleaning, solid-liquid separation and drying on the intermediate product to obtain the sandwich composite material. According to the sandwich composite material disclosed by the invention, the water-based zinc ion battery negative electrode can have excellent cycling stability.

Подробнее
Номер записи: 20
12-05-2023 дата публикации

Materialized view query method, system and equipment and storage medium

Номер: CN116108076A
Автор: YE FEI, YANG ZHIHUI, SHEN YUNFEI, HE ZHENYING, JING YINAN, ZHANG KAI, WANG XIAOYANG
Принадлежит:

The invention relates to a materialized view query method, system and device and a storage medium, and the method comprises the steps: screening a materialized result set obtained by combining historical optimal materialized results of a plurality of historical queries, and selecting a longest materialized result combination meeting a query condition in the materialized result set; the selected materialization result combinations are scored under the dimensions of query response time and query accuracy, the materialization result combinations are output in a layered mode according to the sequence of the scores from high to low, the optimal materialization result is selected through the scores under different dimensions so as to respond to query, and the query efficiency is improved. According to the method, all the materialization results do not need to be sorted in the query process, only one or more times of calculation of the first k scores need to be executed on the materialization ...

Подробнее
Номер записи: 21
20-05-2009 дата публикации

Preparation and use of recombinant mtVEGF121/MAP30KDEL fusion noxioussubstance

Номер: CN0101434657A
Автор: SUN HONGYAN, ZHOU MANXIANG, SHEN YUNFEI, HONGYAN SUN, MANXIANG ZHOU, YUNFEI SHEN
Принадлежит:

The invention discloses a fusion toxin with the effect of selectively killing neovasculature endothelial cells and an application thereof. The fusion toxin is obtained from connecting mtVEGF121 by connecting peptide at the amino terminal of ribosome-inactivating protein of a bitter melon seed. The mtVEGF121, which is taken as a carrier, causes that the fusion toxin is specifically bonded with a growth factor receptor F1k1/KDR of a vasculature endothelial cell and internalized to enter the vasculature endothelial cell and then the toxic effect of MAP30 is exerted to kill the neovasculature endothelial cell and further damage neovasculature. The fusion toxin is simple in expression condition, easy to be purified and liable to be produced in large scale; therefore, the fusion toxin can be taken as an active component for preparing medicaments for resisting a plurality of diseases related to neovasculature enhancement, such as cancer, fundus oculi angiogenesis during late-stage diabetes and ...

Подробнее
Номер записи: 22
18-04-2012 дата публикации

Felodipine sustained-release tablets and preparation method thereof

Номер: CN0101953837B
Автор: MANXIANG ZHOU, YUNFEI SHEN, XUEWEN QIAO, HUILAN ZHANG, ZHOU MANXIANG, SHEN YUNFEI, QIAO XUEWEN, ZHANG HUILAN
Принадлежит:

The invention belongs to the technical field of medicament preparation, and particularly relates to felodipine sustained-release tablets for treating hypertension and a preparation method thereof. The invention aims to solve the technical problems of high oxide content, unstable quality and unsteady dosage release of the conventional felodipine sustained-release tablets. The felodipine sustained-release tablets are prepared from the following components: felodipine cyclodextrin clathrate compound, framework sustained-release material, retardant, filling agent, microcrystalline cellulose, lubricant and flow aid, wherein the components are mixed together to prepare tablet cores, and then the tablet cores are coated by Opadry coating powder. The preparation method specifically comprises the following steps of: firstly, preparing the felodipine cyclodextrin clathrate compound from a cyclodextrin material and felodipine; secondly, preparing the tablet cores from the felodipine cyclodextrinclathrate ...

Подробнее
Номер записи: 23
09-12-2015 дата публикации

Medical treatment energy post

Номер: CN0204840069U
Автор: LU JIANNAN, FENG YIXIN, LIU LINXIAN, JIANG ZHIXING, YU JINGLIANG, SHEN YUNFEI
Принадлежит:

The utility model relates to a medical treatment energy post, including base and panel, be equipped with a plurality of function terminals on the panel, be equipped with the sucking disc on the panel, the panel passes through the sucking disc and adsorbs on the base. The utility model discloses the mounting means is various, easy dismounting, and the function is various.

Подробнее
Номер записи: 24
04-02-2009 дата публикации

Preparation and application of tumour vascular targeting agent VEGF*/RIP30fusion toxin

Номер: CN0101357947A
Автор: SUN HONGYAN, ZHOU MANXIANG, SHEN YUNFEI, HONGYAN SUN, MANXIANG ZHOU, YUNFEI SHEN
Принадлежит:

The invention discloses a fusion toxicant having the function of selectively killing new blood vessel endothelial cells of tumors and an application thereof. The fusion toxicant is a fusion protein which is prepared in the way that the amido ends of ribosome inactivating proteins RIP30 of balsam pear seeds are connected with VEGF121 through connecting peptides. As a carrier, VEGF121 can internalize and bond the fusion toxicant to blood vessel endothelial cell nutrilite receptors F1k1/KDR in a specific way before the fusion toxicant enters blood vessel endothelial cells and plays a role as a toxicant to kill new blood vessel endothelial cells of tumors, to destroy the new blood vessels of tumor tissues and cut off the blood supply of tumors, thus inhibiting tumors. In addition, the expression conditions of the fusion toxicant are simple; the fusion toxicant is purified easily and can be produced in large scale. Accordingly, the fusion toxicant can be used as an active ingredient for preparing ...

Подробнее
Номер записи: 25
19-05-2010 дата публикации

Composite sweetener containing trichlorosucrose and preparation method thereof

Номер: CN0101124960B
Автор: GUOHUA HU, HUI LI, YUNFEI SHEN, ZHENGZHI MA, HU GUOHUA, LI HUI, SHEN YUNFEI, MA ZHENGZHI
Принадлежит:

The present invention relates to a compound sweetening agent that contains trichloro cane sugar. The main ingredient of the present invention is trichloro cane sugar which is a novel high power sweetening agent and which contributes to the main part of sugariness. The trichloro cane sugar is then supermicrocrushed together with high power sweetening agent, such as saccharin sodium and Aspartame before being blended with a carrier to produce a novel compound sweetening agent. The carrier of the invention is dextrine which compensates the sweetness, wherein, the quantity percentages of the trichloro cane sugar, the saccharin sodium, the Aspartame and the dexitrine are 10 percent to 15 percent, 5 percent to 10 percent, 5 percent to 15 percent and 60 to 75 percent respectively. The compound sweetening agent is formulated through science and has the advantages of special favor, sugar-free, low cost and wide market prospects.

Подробнее
Номер записи: 26
23-12-2009 дата публикации

Technique for producing magnesium stearate by dry method and device

Номер: CN0101607884A
Автор: SHEN YUNFEI, LUO MINGZHUANG, YUNFEI SHEN, MINGZHUANG LUO
Принадлежит:

The invention discloses a technique for producing magnesium stearate by a dry method. The technique comprises the following steps of: adding stearate, magnesium compound and water with proportion of 82 to 88%:10 to 15%:2 to 5% into a reactor, stirring and reacting for 1 to 5 hours with temperature of 80 to 120 DEG C and pressure of 0 to 0.10 MPa, and then obtaining the magnesium stearate. The reaction device is characterized in that a motor (1) is connected with a speed reducer (2) which is connected with a gear transmission (3); the gear transmission (3) is connected with a stirrer (9) arranged in a reaction container (4); and a temperature measuring port (5) and a feeding port (6) are arranged above the reaction container (4) which is externally provided with a clamping sleeve (8), and a discharging port (10) is arranged below the reaction container (4). The invention has the advantages of simple technique, little equipment investment, short production period, no wastewater discharging ...

Подробнее
Номер записи: 27
14-09-2011 дата публикации

Application of pyrroloquinoline quinone to the bone marrow hemopoietic function after recovery of radiation

Номер: CN0102178679A
Автор: WEICAI ZHANG, JIANHUA WANG, XIANGHUA XIONG, MANXIANG ZHOU, LIN WEI, YUNFEI SHEN, ZHANG WEICAI, WANG JIANHUA, XIONG XIANGHUA, ZHOU MANXIANG, WEI LIN, SHEN YUNFEI
Принадлежит:

The invention discloses application of pyrroloquinoline quinone to the bone marrow hemopoietic function after recovery of radiation, in particular application of the pyrroloquinoline quinone (PQQ) or a pharmaceutically acceptable salt or ester of the pyrroloquinoline quinine or a medicinal composition containing either salt or ester to preparing drugs for treating bone marrow hemopoietic damage. The tested drug PQQ can be administrated with a certain promoting effect on the recovery of white blood cells, thus being beneficial to the elimination of damaged erythropoiesis factors and the recovery of reticulocytes ratio. A tested drug group and a positive drug group are higher than a contrast group in the number of bone marrow cells, and tend to increase in bone marrow DNA (deoxyribonucleic acid) content. As indicated, the PQQ can promote the recovery of bone marrow hemopoietic function.

Подробнее
Номер записи: 28
23-12-2009 дата публикации

Glucosamine potassium sulfate microcapsule and preparation method and application thereof

Номер: CN0101606922A
Автор: ZHOU MANXIANG, SHEN YUNFEI, ZHANG HUILAN, MANXIANG ZHOU, YUNFEI SHEN, HUILAN ZHANG
Принадлежит:

A glucosamine potassium sulfate microcapsule comprises 15-75% of glucosamine potassium sulfate used as active constituent and other necessary accessories. The preparation method of the glucosamine potassium sulfate microcapsule comprises the following steps: dissolving hydroxypropylmethyl cellulose in 90% of ethanol solution to prepare a 1-10% of solution, then adding plasticizer, antisticking agent and glucosamine potassium sulfate which has the dose corresponding the required dose of the active constituent with a particle size of 150 microns or less than 150 microns, to prepare even suspension and finally obtaining glucosamine potassium sulfate microcapsule through spray drying. The invention coats a macromoleclar polymer film outside the glucosamine potassium sulfate, guarantees the stability of product quality, avoids the absorption of moisture and oxidation of the products and benefits the product storage.

Подробнее
Номер записи: 29
18-06-2014 дата публикации

Fusion toxin with specificity of VEGFR2/KDR acceptor, and coding gene and application thereof

Номер: CN103865899A
Автор: SUN HONGYAN, ZHOU MANXIANG, SHEN YUNFEI
Принадлежит:

The invention discloses a fusion toxin (rhVEGF121KDR/Rgel30) with specificity of VEGFR2/KDR acceptor, and coding gene thereof and application thereof to prepare antitumor medicines. The fusion toxin is obtained by connecting the amino terminal (N terminal) of gelonium multiflorum ribosome inactivating protein rGEL30 to recombinant human vascular endothelial growth factor VEGF121 mutant through a connecting peptide, and the carboxyl terminal (C terminal) of the fusion toxin possesses endoplasmic reticulum positioning sequence. VEGF121KDR taken as a carrying tool helps the fusion toxin to specifically combine with VEGFR2/KDR through high affinity, to be internalized and to enter tumor newborn blood vessel endothelial cells, then ribosome inactivating protein rGEL30 gives a play to toxin effect and kills tumor newborn blood vessel endothelial cells and further destroys newborn blood vessels of tumor tissue for reaching the purpose of inhibiting tumor, and also an endoplasmic reticulum positioning ...

Подробнее
Номер записи: 30
07-10-1998 дата публикации

Soft magnetic ultrasound cleaning dryer

Номер: CN0002293395Y
Автор: SHEN YUNFEI, GE FUQI, WU YONGFENG, YUNFEI SHEN, FUQI GE, YONGFENG WU
Принадлежит: ULTRASOUND ELECTRONIC EQUIPMEN, ULTRASOUND ELECTRONIC EQUIPMENT FACTORY, WUXI CITY

The utility model relates to a soft magnetic ultrasonic cleaning baking machine, which belongs to the technical field of cleaning devices. A cleaning slot is arranged on the upper part of a machine frame, the left and the right sides of the cleaning slot are both provided with a spraying device, a baking system is arranged on the left end of the upper part of the machine frame, a wind knife device is arranged between the baking system and the spraying device, and an ultrasonic cleaning system is arranged in the cleaning slot. The utility model has reasonable structure, reliable performance and good rough cleaning and fine cleaning effects, and the utility model can accomplish batch automatic production. The utility model has ideal effect with adopting the wind knife and the direct baking and solves the problem of water solution which is one of the quality indexes affect the cleaning quality, the utility model satisfy technological requirements and has convenient operation and no environmental ...

Подробнее
Номер записи: 31
04-07-2012 дата публикации

Iron-carbon micro-electrolysis Fenton oxidation reactor

Номер: CN0102190389B
Автор: QIAN PANSHENG, SHEN YUNFEI, PANSHENG QIAN, YUNFEI SHEN
Принадлежит:

The invention discloses an iron-carbon micro-electrolysis Fenton oxidation reactor, which is characterized by comprising a hydrogen peroxide storage tank (1), wherein the outlet of the hydrogen peroxide storage tank (1) is connected with the inlet of a hydrogen peroxide ejector (3); the outlet of an air inlet pipe (5) is connected with the inlet of an air ejector (4); the outlet of the hydrogen peroxide ejector (3), the outlet of the air ejector (4) and a water inlet pipe (6) are connected to one end of a drum (7); the other end of the drum (7) is provided with a water outlet pipe (10); and an iron-carbon filler is arranged in the drum (7). The equipment integrates a micro-electrolysis method with a chemical oxidation method, has the advantages of small occupied area, low cost and modulardesign, is compact, is convenient to operate, and is particularly suitable for treating toxic, harmful and non-biodegradable wastewater such as integrated circuit wastewater, printing and dyeing wastewater ...

Подробнее
Номер записи: 32
09-09-2015 дата публикации

1-(3-hydroxymethylpyridine-2-yl)-4-methyl-2-phenylpiperazine synthesis method

Номер: CN104892608A
Автор: ZHOU MANXIANG, SHEN YUNFEI, ZHOU KAI, WANG FAN, LIU YUPENG
Принадлежит:

The invention discloses a 1-(3-hydroxymethylpyridine-2-yl)-4-methyl-2-phenylpiperazine synthesis method. The method includes: dissolving N-(2-chloroethyl)-N-methyl-alpha-chlorine-beta phenethylamine in mixed solution of water and a nonpolar solvent to obtain solution A, and dissolving 2-amino-3-hydroxymethylpyridine into a nonpolar solvent containing a small quantity of low carbon alcohols to obtain solution B; dripping the solution B into the solution A to obtain an intermediate by reaction, dissolving the intermediate into an anhydrous high-boiling-point polar solvent, and dripping into an anhydrous high-boiling-point polar solvent of inorganic iodides under inert gas shielding to realize reaction for obtaining 1-(3-hydroxymethylpyridine-2-yl)-4-methyl-2-phenylpiperazine. By two steps for synthesis of 1-(3-hydroxymethylpyridine-2-yl)-4-methyl-2-phenylpiperazine, oxidization of the intermediate due to direct high-temperature reaction can be avoided by specific solvent systems, and reaction ...

Подробнее
Номер записи: 33
21-09-2011 дата публикации

Iron-carbon micro-electrolysis Fenton oxidation reactor

Номер: CN0102190389A
Автор: PANSHENG QIAN, YUNFEI SHEN, QIAN PANSHENG, SHEN YUNFEI
Принадлежит:

The invention discloses an iron-carbon micro-electrolysis Fenton oxidation reactor, which is characterized by comprising a hydrogen peroxide storage tank (1), wherein the outlet of the hydrogen peroxide storage tank (1) is connected with the inlet of a hydrogen peroxide ejector (3); the outlet of an air inlet pipe (5) is connected with the inlet of an air ejector (4); the outlet of the hydrogen peroxide ejector (3), the outlet of the air ejector (4) and a water inlet pipe (6) are connected to one end of a drum (7); the other end of the drum (7) is provided with a water outlet pipe (10); and an iron-carbon filler is arranged in the drum (7). The equipment integrates a micro-electrolysis method with a chemical oxidation method, has the advantages of small occupied area, low cost and modular design, is compact, is convenient to operate, and is particularly suitable for treating toxic, harmful and non-biodegradable wastewater such as integrated circuit wastewater, printing and dyeing wastewater ...

Подробнее
Номер записи: 34
12-03-2008 дата публикации

Natural glycosides component having good effect of reducing blood sugar

Номер: CN0101138567A
Автор: LI JUNLIN, ZHOU MANXIANG, SHEN YUNFEI, JUNLIN LI, MANXIANG ZHOU, YUNFEI SHEN
Принадлежит:

The invention discloses a natural small-molecule glycoside compound of better hypoglycemic activity, which is selected from the natural similar compounds through screening test. The invention provides a better choice for the development of the compound and the new drug in clinically treating diabetes.

Подробнее
Номер записи: 35
22-04-2015 дата публикации

Error quaternion-based transmission aligning method under large heading misalignment angle

Номер: CN104535080A
Автор: GAO WEI, SHAN WEI, XU BO, LI CHAO, SHEN YUNFEI, ZHAO PENG, LIU YANG, QIU LIMIN, DENG LIYING, HE HAO
Принадлежит:

The invention discloses an error quaternion-based transmission aligning method under a large heading misalignment angle. The method comprises the following steps: arranging a main inertial navigation system and a slaver inertial navigation system on a carrier, completing the self alignment process of the master inertial navigation system, and establishing a master inertial navigation carrier system; directly giving obtained navigation information of the main inertial navigation system to the slaver inertial navigation system to be aligned as an initial value to complete binding coarse alignment of the current slaver inertial navigation system; calculating to obtain a misalignment angle between the slaver inertial navigation system and the master inertial navigation system, and equivalently transforming the misalignment angle to an error quaternion; regarding the dynamic deformation angle in the misalignment angle as a white noise process in order to obtain white noise process parameters ...

Подробнее
Номер записи: 36
08-04-2009 дата публикации

Food sweetening agent

Номер: CN0101401634A
Автор: YUNFEI SHEN, SHEN YUNFEI
Принадлежит:

The invention discloses a food sweetening agent, which comprises the following raw materials in portion by mass: 0.1 to 8.3 portions of sucralose, and 91.7 to 99.9 portions of mixture of oligoisomaltose and filler, wherein the raw materials comprise 0 to 98.9 portions of the filler. The food sweetening agent takes the sucralose as a main sweetness source to select reasonable auxiliary materials and filler, provides the sweetness for food due to the mixing according to the reasonable mixture ratio, has high similar degree of the taste with saccharose, and has no peculiar smell, harsh taste and bitter taste; the acid-alkali property in the food has no any influence on the food sweetening agent, so the food sweetening agent can be used for any food batching system and processing course; the food sweetening agent has small using amount and low heat, is equivalent to one fortieth of the amount of the saccharose with the same saccharinity, and can not cause the fatness; after the intake, the ...

Подробнее
Номер записи: 37