A METHOD FOR GENERATING RANDOM OLIGONUCLEOTIDES AND DETERMINING THEIR SEQUENCE

Random oligonucleotides are generated with incomplete information about the sequence of the nucleic acid bases present in the newly generated molecules. The sequences of the oligonucleotides are subsequently determined and then these oligonucleotides can be processed for various potential uses. 1. A method of generating an oligonucleotide , the method comprising:a. generating at least one molecule comprising nucleotides by adding at least one nucleotide at random to the molecule, wherein the molecule generated is a random oligonucleotide;b. determining the sequence of the random oligonucleotide; andc. selecting random oligonucleotides using certain characteristics of the random oligonucleotides.2. The method of wherein the random oligonucleotides are generated using phosphoramidite chemistry.3. The method of claim 1 , wherein the random oligonucleotides are generated using an enzymatic process.4. The method of claim 1 , wherein the random oligonucleotides are generated within a microwell.5. The method of claim 1 , wherein the random oligonucleotides are generated on a microarray.6. The method of wherein the characteristic used to select the random oligonucleotide is a specific sequence of nucleotides.7. The method of wherein the characteristic to select the random oligonucleotide is a size of the random oligonucleotide.8. The method of wherein the random oligonucleotides are generated on oligonucleotides having a sequence that is at least partially known.9. The method of claim 3 , wherein an indicator molecule becomes reactive after a nucleotide is added to the molecule.10. The method of wherein adding a nucleic acid base to the molecules is partially directed.11. The method of claim 1 , wherein microfluids are used to control reaction conditions.12. The method of wherein directed energy is used to control the reaction conditions.13. The method of where the properties of the random oligonucleotide are measured using a nanopore.14. The method of wherein the selected ...

Concealing information present within nucleic acids

Methods related to concealment of genetic information present within nucleic acid sequences, wherein individual nucleic acid molecules are barcoded. In some embodiments barcoding occurs before, after, or during enrichment. Barcoded nucleic acids are then combined with control barcoded nucleic acids. Different methods are provided for barcoding and pooling to conceal different types of genetic information present within nucleic acids.

A method for generating random oligonucleotides and determining their sequence

Random oligonucleotides are generated with incomplete information about the sequence of the nucleic acid bases present in the newly generated molecules. The sequences of the oligonucleotides are subsequently determined and then these oligonucleotides can be processed for various potential uses.

A method for generating random oligonucleotides and determining their sequence

A method for generating random oligonucleotides and determining their sequence

Security device for obfuscating and securing lab equipment

Data protection systems and methods. One system includes comprising a network security device including a security module and a firewall. The network security device is configured as an intermediary device between laboratory equipment and a communication network. The network security device includes a memory storing one or more applications, an input/output interface configured to receive data generated by the laboratory equipment, and an electronic processor. The electronic processor configured to, through execution of the one or more applications, modify the data received from the laboratory equipment to protect sensitive data included in the data, encrypt the data, as modified, to generate a data file, transfer the data file to one or more devices over the network, and prevent network traffic from reaching the laboratory equipment.