Multiple-firing crimp device and methods for using and manufacturing same

A multiple-firing crimp device comprises crimps, a shaft, a crimp movement assembly, and a snare. Each crimp has an internal hollow. The shaft has a distal crimping location, an exterior surface, and an interior with the clips stacked therein, the crimps moving therein along a longitudinal axis. The shaft defines a lateral opening proximal to the crimping location and communicates the interior to the environment outside the exterior surface. The crimp movement assembly within the shaft delivers the first crimp to the distal crimping location by moving the first crimp longitudinally from a first proximal position into the distal crimping location and returning to a second proximal position without the first crimp. The snare pulls at least one cord from distal of the first crimp through the first crimp and through a portion of the shaft and out the side of the shaft through the lateral opening.

Aspiration thrombectomy system and methods for thrombus removal with aspiration catheter

A clot removal system comprises a catheter, a vacuum source, and a controller. The catheter comprises a proximal end, a distal end, and controller operating parameters and defines a lumen configured to be filled with a liquid column having a proximal portion. The vacuum source is configured to supply vacuum. The controller is configured to carry out a control pattern of turning on and off the vacuum based upon the controller operating parameters and is configured to receive the controller operating parameters in an automatic response to the catheter being operatively connected to at least one of the vacuum source and the controller and, responsive to the connection, to carry out the control pattern to change a level of vacuum at the distal end of the catheter.

Earphone

Transcutaneous electrostimulator and methods for electric stimulation

An electrostimulation device includes a computer generating an electrostimulation generator control signal and outputting a music signal, a transcutaneous electrostimulation generator, an electronic signal conduit, and an electrode coupler. The generator receives the generator control signal and the music signal, generates a nerve electrostimulation signal dependent upon the generator control signal, and outputs the nerve electrostimulation signal at the stimulation output and the music signal at an audio output. The coupler fits in an ear canal, has a speaker connected to the audio output to output the music signal into the ear canal when worn, and has electrostimulation electrodes conductively connected to the stimulation output through the electronic signal conduit to receive the nerve electrostimulation signal and positioned to contact tissue within the canal to transcutaneously apply the nerve electrostimulation signal thereto. The coupler supplies the nerve electrostimulation signal ...

Aspiration thrombectomy system and methods for thrombus removal with aspiration catheter

A clot removal system comprises a catheter, a vacuum source, and a controller. The catheter comprises a proximal end, a distal end, and controller operating parameters and defines a lumen configured to be filled with a liquid column having a proximal portion. The vacuum source is configured to supply vacuum. The controller is configured to carry out a control pattern of turning on and off the vacuum based upon the controller operating parameters and is configured to receive the controller operating parameters in an automatic response to the catheter being operatively connected to at least one of the vacuum source and the controller and, responsive to the connection, to carry out the control pattern to change a level of vacuum at the distal end of the catheter.

Methods and apparatus for controlling the internal circumference of an anatomic orifice or lumen

An implantable device is provided for controlling shape and/or size of an anatomical structure or lumen. The implantable device has an adjustable member configured to adjust the dimensions of the implantable device. The implantable device is housed in a catheter and insertable from a minimally invasive surgical entry. An adjustment tool actuates the adjustable member and provide for adjustment before, during or after the anatomical structure or lumen resumes near normal to normal physiologic function.

Multiple-firing securing device and methods for using and manufacturing same

A multiple-fire securing device includes a hollow outer shaft, a reloader, a reloader movement assembly, a rail, and securing structures each defining an inner securing orifice. The reloader longitudinally moves within the outer shaft and has a distal end shaped to temporarily contact one of the securing structures. The rail is disposed within the reloader and has an installing location. The securing structures are disposed on the rail. The reloader movement assembly moves the reloader longitudinally in a distal direction to deliver a first securing structure to the installing location from a first proximal position and moves the reloader proximally away from the installing location without the first securing structure to a position in which the distal end of the reloader temporarily contacts a second one of the securing structures. The second and successive securing structures are moved one at a time to the installing location.

Transcutaneous Electrostimulator and Methods for Electric Stimulation

A transcutaneous electrostimulation device includes an electrostimulation generator providing at an output a nerve electro stimulation signal, an electronic signal conduit conductively connected to the output of the generator, and an electrode coupler shaped to form fit an ear canal of a human ear and having at least one electrostimulation electrode. The electrode is conductively connected to the electronic signal conduit to receive the nerve electrostimulation signal and is positioned at the electrode coupler to contact tissue within an ear canal and apply the nerve electrostimulation signal to the tissue transcutaneously. An audio source outputs audio signals. The electrode coupler has a speaker receiving the audio signals for output into the ear canal when the electrode coupler is worn. The generator sends the nerve electrostimulation signal to the electrode coupler while the audio signals are output. The generator modulates the nerve electrostimulation signal based upon the audio signals. 1. A transcutaneous electrostimulation device , comprising:an electrostimulation generator providing at an output a nerve electrostimulation signal;an electronic signal conduit conductively connected to the output of the electrostimulation generator; and conductively connected to the electronic signal conduit to receive the nerve electrostimulation signal; and', 'positioned at the at least one electrostimulation electrode coupler to contact tissue within an ear canal and apply the nerve electrostimulation signal to the tissue transcutaneously., 'an electrode coupler shaped to form fit an ear canal of a human ear and having at least one electrostimulation electrode2. The device according to claim 1 , wherein the nerve electrostimulation signal is a vagus nerve electrostimulation signal.3. The device according to claim 1 , wherein the nerve electrostimulation signal is a trigeminal nerve electrostimulation signal.4. The device according to claim 1 , wherein:the electrode coupler ...

Left Atrial Appendage Clipping Device and Methods for Clipping the LAA

An LAA exclusion clip includes first and second clip struts and a bias device. The clip struts together define a heart-proximate side, a heart-distal side, bias and open clip ends, each strut having a tissue-contacting surface disposed opposite one another. The bias device includes a first biasing portion connecting the first and second clip struts, disposed on the heart-proximate side of the clip struts, and crossing over from the first clip strut to the second clip strut at the heart-proximate side of the first and second clip struts adjacent the bias clip end. The bias device includes a second biasing portion connecting the first and second clip struts, disposed on the heart-distal side of the first and second clip struts, and crossing over from the first clip strut to the second clip strut at the heart-distal side of the first and second clip struts adjacent the bias clip end. 1. An external left atrial appendage (LAA) exclusion clip , comprising: a heart-proximate side;', 'a heart-distal side;', 'a bias clip end; and', 'an open clip end opposite the bias clip end;, 'first and second clip struts together definingeach strut having a tissue-contacting surface and being disposed opposite one another to face the tissue-contacting surfaces of the clip struts towards one another; [ connecting the first clip strut to the second clip strut;', 'disposed on the heart-proximate side of the first and second clip struts; and', 'crossing over from the first clip strut to the second clip strut at the heart-proximate side of the first and second clip struts adjacent the bias clip end; and, 'a first biasing portion, connecting the first clip strut to the second clip strut;', 'disposed on the heart-distal side of the first and second clip struts; and', 'crossing over from the first clip strut to the second clip strut at the heart-distal side of the first and second clip struts adjacent the bias clip end., 'a second biasing portion], 'a bias device comprising2. The clip according ...

MULTIPLE-FIRING SECURING DEVICE AND METHODS FOR USING AND MANUFACTURING SAME

A multiple-fire securing device includes a hollow outer shaft, a reloader, a reloader movement assembly, a rail, and securing structures each defining an inner securing orifice. The reloader longitudinally moves within the outer shaft and has a distal end shaped to temporarily contact one of the securing structures. The rail is disposed within the reloader and has an installing location. The securing structures are disposed on the rail. The reloader movement assembly moves the reloader longitudinally in a distal direction to deliver a first securing structure to the installing location from a first proximal position and moves the reloader proximally away from the installing location without the first securing structure to a position in which the distal end of the reloader temporarily contacts a second one of the securing structures. The second and successive securing structures are moved one at a time to the installing location. 1. A multiple-fire securing device , comprising:a plurality of securing structures each defining an inner securing orifice;a hollow outer shaft; longitudinally movable within the outer shaft; and', 'having a distal end shaped to temporarily contact one of the securing structures;, 'a reloadera rail disposed within the reloader and on which the plurality of securing structures are disposed, the rail having an installing location; and moving the reloader longitudinally in a distal direction to deliver a first securing structure to the installing location from a first proximal position; and', 'moving the reloader proximally away from the installing location without the first securing structure to a position in which the distal end of the reloader temporarily contacts a second one of the securing structures., 'a reloader movement assembly2. The device according to claim 1 , wherein the inner clipping orifice is an H-shaped orifice.3. The device according to claim 1 , wherein the rail has an H-shape cross-section.4. The device according to claim ...

Actively controllable stent, stent graft, heart valve and method of controlling same

Sealable and repositionable implant devices are provided to increase the ability of endovascular grafts and valves to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes a self-expanding stent of a shape-memory material set to a given shape. The stent has a wall with a portion having a first thickness and a second portion having a thickness greater than the first. The second portion defines a key-hole shaped longitudinal drive orifice. The implant includes a selectively adjustable assembly having adjustable elements and being operable to force a configuration change in at least a portion of the self-expanding stent. The adjustable elements have a part rotatably disposed within the longitudinal drive orifice.

Actively Controllable Heart Valve Implant and Method of Controlling Same

A mitral valve implant includes a force-expanding mitral valve lattice having an interior orifice and a self-expanding valve trampoline attached at the interior orifice of the force-expanding mitral valve lattice. The mitral valve lattice is self-expandable to a first configuration and force expandable from the first configuration to a second configuration. The configurations can be circular or D-shaped. The mitral valve lattice comprises jack screws adjusting configurations of the mitral valve lattice. The valve trampoline has a cylindrical central region comprising valve leaflets. An outwardly flaring implant skirt is attached to the mitral valve lattice exterior. Wall-retaining wires are attached to the mitral valve lattice, are petal-shaped, and have a pre-set, radially outward, memory shape. The wires and skirt impart a force on a respective side of the native mitral valve when the mitral valve lattice is expanded within an annulus of the native mitral valve.

ACTIVELY CONTROLLABLE STENT, STENT GRAFT, HEART VALVE AND METHOD OF CONTROLLING SAME

A delivery apparatus comprises a handle portion and at least one rotatable drive shaft. The handle portion has an actuation mechanism and a display. The actuation mechanism includes a motor and one or more actuators. The rotatable drive shaft has a proximal end portion and a distal end portion. The proximal end portion is coupled to the motor, and the distal end portion is configured to be releasably coupled to a prosthetic heart valve. The actuation mechanism is configured to control and monitor expansion of the prosthetic heart valve, and the display is configured to display a diameter of the prosthetic heart valve. 1. A delivery apparatus , comprising:a handle portion having an actuation mechanism and a display, wherein the actuation mechanism includes a motor and one or more actuators; andat least one rotatable drive shaft having a proximal end portion and a distal end portion, wherein the proximal end portion is coupled to the motor, and the distal end portion is configured to be releasably coupled to a prosthetic heart valve,wherein the actuation mechanism is configured to control and monitor expansion of the prosthetic heart valve, andwherein the display is configured to display a diameter of the prosthetic heart valve.2. The delivery apparatus of claim 1 , wherein the display is configured to display a radial force imparted to native heart valve tissue by the prosthetic heart valve.3. The delivery apparatus of claim 1 , wherein the display is a digital display.4. The delivery apparatus of claim 1 , wherein the displayed diameter of the prosthetic heart valve is a real-time diameter of the prosthetic heart valve.5. The delivery apparatus of claim 1 , wherein the display is configured to display the diameter of the prosthetic heart valve as a circle that has a diameter that is the same as the diameter of the prosthetic heart valve.6. The delivery apparatus of claim 1 , wherein the actuation mechanism is configured to expand the prosthetic heart valve from a ...

Actively Controllable Stent, Stent Graft, Heart Valve and Method of Controlling Same

Sealable and repositionable implant devices are provided with features that increase the ability of implants such as endovascular grafts and valves to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and/or with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes an implant body and a selectively adjustable assembly attached to the implant body, the assembly having adjustable elements and being operable to cause a configuration change in a portion of the implant body and, thereby, permit implantation of the implant body within an anatomic orifice to effect a seal therein under normal physiological conditions.

METHODS FOR CONTROLLING THE INTERNAL CIRCUMFERENCE OF AN ANATOMIC ORIFICE OR LUMEN

A method for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural orifice or lumen which is either too large or too small. Implants are disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like.

Left atrial appendage clipping device and methods for clipping the LAA

An LAA exclusion clip includes first and second clip struts and a bias device. The clip struts together define a heart-proximate side, a heart-distal side, bias and open clip ends, each strut having a tissue-contacting surface disposed opposite one another. The bias device includes a first biasing portion connecting the first and second clip struts, disposed on the heart-proximate side of the clip struts, and crossing over from the first clip strut to the second clip strut at the heart-proximate side of the first and second clip struts adjacent the bias clip end. The bias device includes a second biasing portion connecting the first and second clip struts, disposed on the heart-distal side of the first and second clip struts, and crossing over from the first clip strut to the second clip strut at the heart-distal side of the first and second clip struts adjacent the bias clip end.

ASPIRATION THROMBECTOMY SYSTEM AND METHODS FOR THROMBUS REMOVAL WITH ASPIRATION CATHETER

A method of operating an aspiration catheter having a proximal end and a distal end includes the acts of at least partially blocking the distal end of the aspiration catheter with an embolus, creating a vacuum at the distal end of the aspiration catheter with a vacuum source adjacent the proximal end of the aspiration catheter, at least partially relieving the vacuum at the distal end of the catheter by at least one of interrupting the vacuum from the vacuum source and venting the aspiration catheter with a vent fluid adjacent the proximal end, and repeating the acts of interrupting the vacuum and venting the aspiration catheter in a timing cycle that maximizes the time that the aspiration catheter is at vacuum and changes pressure at the distal end of the catheter from vacuum to at least atmospheric pressure during each cycle.

ASPIRATION THROMBECTOMY SYSTEM AND METHODS FOR THROMBUS REMOVAL WITH ASPIRATION CATHETER

A clot removal system comprises a catheter, a vacuum source, and a controller. The catheter comprises a proximal end, a distal end, and controller operating parameters and defines a lumen configured to be filled with a liquid column having a proximal portion. The vacuum source is configured to supply vacuum. The controller is configured to carry out a control pattern of turning on and off the vacuum based upon the controller operating parameters and is configured to receive the controller operating parameters in an automatic response to the catheter being operatively connected to at least one of the vacuum source and the controller and, responsive to the connection, to carry out the control pattern to change a level of vacuum at the distal end of the catheter.

Transcutaneous electrostimulator and methods for electric stimulation

An electrostimulation device comprises a hand-held electrostimulation generator receiving an input music signal and providing at an output a nerve electrostimulation signal modulated by the music signal, an electronic signal conduit having conductive leads conductively connected to the output of the electrostimulation generator, and an electrode coupler comprising an earbud. The earbud is shaped to form fit inside an ear canal of a human ear and composed of a pliable material conforming to the ear canal when inserted therein, the pliable material forming at least two electrostimulation electrodes conductively connected to a respective one of the conductive leads of the electronic signal conduit to receive the nerve electrostimulation signal and transmitting the nerve electrostimulation signal to at least two different, electrically conductive exterior surface portions of the pliable material and transcutaneously applying the nerve electrostimulation signal from the conductive leads to tissue ...

Implantable devices for controlling the size and shape of an anatomical structure or lumen

An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ.

Left Atrial Appendage Clipping Device and Methods for Clipping the LAA

An LAA exclusion system includes a clip comprising first and second separate clip struts, and a bias device comprising spring portions, and a delivery device having clip-contacting ends. The first clip strut has a first proximal end. The second clip strut has a second proximal end adjacent the first proximal end. The clip struts together define a first exterior surface and an opposing second exterior surface. The first spring portion connects the first clip strut to the second clip strut along the first exterior surface and the second spring portion connects the first clip strut to the second clip strut along the second exterior surface. The spring portions define therebetween a strut-securing area at the first and second proximal ends. The clip-contacting ends are configured to removably connect to the proximal ends of the clip struts through the strut-securing area.

Rapid infusion system

A rapid infusion system for the intravenous delivery of fluids at standard and rapid flow rates. The system includes a pump assembly, a drive assembly to power the pump, and a fluid containment system that keeps the infused fluid out of direct contact with the pump assembly and that is preferably disposable and removable. In one embodiment the drive assembly includes a differential drive that interacts with more than one motor. In one embodiment, the pump assembly includes a roller pump and the pump chamber is a collapsible, preformed tube that is preferably attached to a pump cartridge frame. Optionally, the system includes a self-leveling drip chamber and the fluid containment system is disposable and includes a pump cartridge containing the drip chamber and the pump chamber, I.V. tubing, outlet infusion tubing, and a heater cartridge.

Fluid heat exchanger and airtrap

The present invention relates to a system for increasing the temperature of a fluid being infused into a patient's body while the infusion is taking place. The present invention also provides for improved monitoring of air in the infusion system such to prevent the introduction of air into the patient's body receiving the fluid infusion. The present invention also provides for a system pump which provides a variable flow rate that serves a vast amount of infusion needs and purposes. A disposable cartridge in accordance with the present invention will allow for the efficient transfer of heat energy to the fluid being infused into the patient's body. The cartridge will further ensure that deleterious amounts of air will not be introduced into the patient's body.

ASPIRATION THROMBECTOMY SYSTEM AND METHODS FOR THROMBUS REMOVAL WITH ASPIRATION CATHETER

A clot removal system includes a catheter having proximal and distal ends and defining a lumen configured to be filled with a liquid column having a proximal portion, a vacuum pump supplying vacuum, a vent container holding vent liquid, a vent valve configured to fluidically communicate with the vent liquid and with the proximal portion of the liquid column at the proximal end of the catheter, a vacuum valve configured to fluidically communicate with the vacuum and with the proximal portion of the liquid column at the proximal end of the catheter, and a controller configured to carry out a pre-determined pattern of opening and closing the vent and vacuum valves to change a level of vacuum at the distal end and, while changing the level of vacuum at the distal end, to substantially prevent forward flow of the liquid at a distal end of the liquid column. 1. A clot removal system , comprising:a catheter having a proximal end and a distal end and defining a lumen configured to be filled with a liquid column having a proximal portion;a vacuum pump configured to supply vacuum;a vent container holding a vent liquid; with the vent liquid in the vent container; and', 'with the proximal portion of the liquid column at the proximal end of the catheter;, 'a vent valve configured to fluidically communicate with the vacuum from the vacuum pump; and', 'with the proximal portion of the liquid column at the proximal end of the catheter; and, 'a vacuum valve configured to fluidically communicatea controller configured to carry out a pre-determined pattern of opening and closing the vent and vacuum valves to change a level of vacuum at the distal end and, while changing the level of vacuum at the distal end, to substantially prevent forward flow of liquid at a distal end of the liquid column.2. The system according to claim 1 , wherein the liquid at the distal end of the liquid column is one or more of albumin claim 1 , d5W water claim 1 , normal saline claim 1 , half-normal saline ...

Implantable devices for controlling the internal circumference of an anatomic orifice or lumen

An implantable device for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implants are disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like ...

TRANSCUTANEOUS ELECTROSTIMULATOR AND METHODS FOR ELECTRIC STIMULATION

An electrostimulation device includes a computer generating an electrostimulation generator control signal and outputting a music signal, a transcutaneous electrostimulation generator, an electronic signal conduit, and an electrode coupler. The generator wirelessly receives the generator control signal and the music signal, generates a nerve electrostimulation signal dependent upon the generator control signal, and wirelessly outputs the nerve electrostimulation signal at the stimulation output and the music signal at an audio output. The coupler fits in an ear canal, has a speaker connected to the audio output to output the music signal into the ear canal when worn, and has electrostimulation electrodes wirelessly connected to the stimulation output through the electronic signal conduit to receive the nerve electrostimulation signal and positioned to contact tissue within the canal to transcutaneously apply the nerve electrostimulation signal thereto. The coupler supplies the nerve electrostimulation signal while music outputs from the speaker. 1. An electrostimulation device , comprising:a computer generating an electrostimulation generator control signal; receiving the electrostimulation generator control signal wirelessly;', 'generating a nerve electrostimulation signal dependent upon the electrostimulation generator control signal; and', 'outputting the nerve electrostimulation signal at the stimulation output;, 'a transcutaneous electrostimulation generator having a stimulation output anda wireless electronic signal conduit connected to the stimulation output; and a tragus boom comprising as a first electrostimulation electrode having a first tragus contact that is connected to the wireless electronic signal conduit to receive the nerve electrostimulation signal;', a second electrostimulation electrode having a canal contact connected to the wireless electronic signal conduit to receive the nerve electrostimulation signal;', 'a second tragus contact;', 'a ...

Modified laryngoscope blade to reduce dental injuries during intubation

The present invention relates to the field of medical devices used in the procedures of orotracheal or nasotracheal intubation. Oral or nasal endotracheal intubation procedures are commonly employed to secure a controlled airway and to deliver inhalant oxygen, anesthetic gases, and other therapeutic agents into the trachea and lungs of human and veterinary patients. Such intubation procedures carry a significant risk of dental injury resulting from contact between the laryngoscope blade used for visualization during intubation. The present invention provides an apparatus to reduce dental injury including a modified laryngoscope blade and a disposable insert which is designed to be received and retained in a single step by the modified laryngoscope blade. The disposable insert may be quickly secured by the user, and reduces both direct pressure and shear forces on the maxillary incisor teeth when the laryngoscope blade is placed in a patient's mouth during intubation.

ASPIRATION THROMBECTOMY SYSTEM AND METHODS FOR THROMBUS REMOVAL WITH ASPIRATION CATHETER

A clot removal system comprises a catheter, a vacuum source, and a controller. The catheter comprises a proximal end, a distal end, and controller operating parameters and defines a lumen configured to be filled with a liquid column having a proximal portion. The vacuum source is configured to supply vacuum. The controller is configured to carry out a control pattern of turning on and off the vacuum based upon the controller operating parameters and is configured to receive the controller operating parameters in an automatic response to the catheter being operatively connected to at least one of the vacuum source and the controller and, responsive to the connection, to carry out the control pattern to change a level of vacuum at the distal end of the catheter.

Portable electronic device

ASPIRATION THROMBECTOMY SYSTEM AND METHODS FOR THROMBUS REMOVAL WITH ASPIRATION CATHETER

A clot removal system comprises a catheter, a vacuum source, and a controller. The catheter comprises a proximal end, a distal end, and controller operating parameters and defines a lumen configured to be filled with a liquid column having a proximal portion. The vacuum source is configured to supply vacuum. The controller is configured to carry out a control pattern of turning on and off the vacuum based upon the controller operating parameters and is configured to receive the controller operating parameters in an automatic response to the catheter being operatively connected to at least one of the vacuum source and the controller and, responsive to the connection, to carry out the control pattern to change a level of vacuum at the distal end of the catheter.

RENEWABLE ENERGY SYSTEM AND METHODS FOR CREATING RENEWABLE ENERGY

A renewable energy device includes a wheel rotatably mounted on a base to spin about an axis of rotation and having a plurality of hollow, barbell-shaped fluid subassemblies fixed symmetrically about the axis. The fluid subassemblies each have a longitudinal axis radiating away from the axis of rotation, a hollow outer end defining a circular, ring-shaped, outer travel path when rotated about the axis of rotation, a hollow inner end defining a circular, ring-shaped, travel path disposed within the outer travel path when rotated about the axis of rotation, a hollow conduit fluidically connecting the outer and inner ends to define an interior cavity, and a room-temperature-boiling-point fluid disposed in the interior cavity. Inner and outer thermal variance subassemblies cover approximately half of respective ones of the inner and outer travel paths on at least one side of the wheel. 1. A renewable energy device , comprising:a base; a longitudinal axis radiating away from the axis of rotation;', 'a hollow outer end defining a circular, ring-shaped, outer travel path when rotated about the axis of rotation:', 'a hollow inner end defining a circular, ring-shaped, travel path disposed within the outer travel path when rotated about the axis of rotation;', 'a hollow conduit fluidically connecting the outer and inner ends to define an interior cavity; and', 'a fluid disposed in the interior cavity, the fluid having a boiling point of near the same temperature as the environment surrounding the fluid subassembly;, 'a wheel rotatably mounted on the base to spin about an axis of rotation and comprising a plurality of hollow fluid subassemblies fixed to the wheel symmetrically about the axis of rotation, the fluid subassemblies each havingan outer shield covering approximately half of the outer travel path on at least one side of the wheel; andan inner shield covering approximately half of the inner travel path on at least the one side of the wheel.2. The device according to ...

RECAPTURABLE LEFT ATRIAL APPENDAGE CLIPPING DEVICE AND METHODS FOR RECAPTURING A LEFT ATRIAL APPENDAGE CLIP

A recapturable external LAA exclusion clip system includes a clip comprising first and second clip struts, at least one of the struts having a connector interface comprising a first portion of a lock, and a delivery device comprising a handle and an end effector. The handle comprises jaw and lock controls. The end effector is connected to the handle and comprises a clevis and first and second jaws. The jaws are connected to the clevis and operatively connected to the jaw control to actively articulate at least one of the jaws with respect to the other. At least one of the jaws has a connector comprising a second portion of the lock operatively connected to the lock control to removably lock with the first portion of the lock. The first and second portions of the lock have a locked state and are configured to unlock the locked state upon actuation of the lock control.

ACTIVELY CONTROLLABLE STENT, STENT GRAFT, HEART VALVE AND METHOD OF CONTROLLING SAME

An assembly includes a prosthetic heart valve and a delivery apparatus. The prosthetic heart valve has a plurality of pivotably connected struts and one or more adjustable elements rotatably coupled to the struts. Rotating the adjustable elements in a first direction relative to the struts radially expands the prosthetic heart valve. Rotating the adjustable elements in a second direction relative to the struts radially contracts the prosthetic heart valve. The delivery apparatus includes one or more motors, one or more drive wires coupled to the motors, and a memory. The drive wires are coupled to the adjustable elements of the prosthetic heart valve. The motors are configured to rotate the drive wires and the adjustable elements to expand and contract the prosthetic heart valve. The memory is configured for storing one or more characteristics of the motors, the drive wires, or the prosthetic heart valve. 1. An assembly , comprising:a prosthetic heart valve having a plurality of pivotably connected struts and one or more adjustable elements rotatably coupled to the struts, wherein rotating the adjustable elements in a first direction relative to the struts radially expands the prosthetic heart valve, and wherein rotating the adjustable elements in a second direction relative to the struts radially contracts the prosthetic heart valve; anda delivery apparatus including one or more motors, one or more drive wires coupled to the motors, and a memory, wherein the drive wires are coupled to the adjustable elements of the prosthetic heart valve, wherein the motors are configured to rotate the drive wires and the adjustable elements to expand and contract the prosthetic heart valve, and wherein the memory is configured for storing one or more characteristics of the motors, the drive wires, or the prosthetic heart valve.2. The assembly of claim 1 , wherein the characteristics stored in the memory of the delivery apparatus include first characteristics corresponding to ...

Aspiration Thrombectomy System and Methods for Thrombus Removal with Aspiration Catheter

A clot removal system comprises a catheter, a vacuum source, and a controller. The catheter comprises a proximal end, a distal end, and controller operating parameters and defines a lumen configured to be filled with a liquid column having a proximal portion. The vacuum source is configured to supply vacuum. The controller is configured to carry out a control pattern of turning on and off the vacuum based upon the controller operating parameters and is configured to receive the controller operating parameters in an automatic response to the catheter being operatively connected to at least one of the vacuum source and the controller and, responsive to the connection, to carry out the control pattern to change a level of vacuum at the distal end of the catheter. 1. A clot removal system , comprising: comprising a proximal end, a distal end, and controller operating parameters; and', 'defining a lumen configured to be filled with a liquid column having a proximal portion;, 'a cathetera vacuum source configured to supply vacuum; and configured to carry out a control pattern of turning on and off the vacuum based upon the controller operating parameters; and', 'configured to receive the controller operating parameters in an automatic response to the catheter being operatively connected to at least one of the vacuum source and the controller and, responsive to the connection, to carry out the control pattern to change a level of vacuum at the distal end of the catheter., 'a controller2. The system according to claim 1 , wherein the controller operating parameters are stored in the catheter and are provided to the controller responsive to the connection.3. The system according to claim 1 , wherein the catheter comprises an extension line:having a first end connected to the catheter and a second end connected to at least one of the vacuum source and the controller; and configured to provide the controller operating parameters to the controller; and', 'fluidically connecting ...

Rapid Infusion System

A rapid infusion system for the intravenous delivery of fluids at standard and rapid flow rates. The system includes a pump assembly, a drive assembly to power the pump, and a fluid containment system that keeps the infused fluid out of direct contact with the pump assembly and that is preferably disposable and removable. In one embodiment the drive assembly includes a differential drive that interacts with more than one motor. In one embodiment, the pump assembly includes a roller pump and the pump chamber is a collapsible, preformed tube that is preferably attached to a pump cartridge frame. Optionally, the system includes a self-leveling drip chamber and the fluid containment system is disposable and includes a pump cartridge containing the drip chamber and the pump chamber, I.V. tubing, outlet infusion tubing, and a heater cartridge.

Prosthetic heart valve

A novel durable prosthetic heart valve compatible with implantation in a human natural heart valve annulus. The prosthetic heart valve comprises a tubular heart valve which in function resembles a human heart valve, but which is formed of either synthetic or biologic material. The present valve is capable of structurally complying with annular deformation during each heartbeat. Valve embodiments comprise aortic, mitral, tricuspid, and pulmonic implantable valves. Valves can be selectively impregnated with a group of biologically active substances consisting of antibiotics, bactericidal agents, anticoagulant medications, endothelial cells, genetic material, growth factors or other hormonal or biologically active substances. Use of non-thrombogenic biocompatible materials in the valve which mimics operation of a natural heart valve essentially eliminates the need for long term administration of anticoagulants. The current configuration of the valve allows for either percutaneous placement or placement through open techniques.

ASPIRATION THROMBECTOMY SYSTEM AND METHODS FOR THROMBUS REMOVAL WITH ASPIRATION CATHETER

A thrombectomy removal system includes a catheter having a distal end and defining a lumen filled with a liquid column having a proximal portion and a distal portion, a vacuum source, a vent liquid source, and a vacuum and vent control system configured to cyclically connect or disconnect the vacuum source and the vent liquid source to change a level of vacuum at the distal end and substantially prevent forward flow. The vacuum source and the vent source are respectively fluidically connected to the vacuum and vent valves. A manifold connects the proximal portion to the vacuum and vent sources through the valves. Control of the valves prevents forward flow of the distal portion out from the distal end during each cycle. Each cycle can have states including vacuum-only, first double-closed, vent-only, and second double-closed. A time of the double-closed states can be no greater than 30 ms. 1. A clot removal system , comprising:a catheter having a distal end and defining a lumen filled with a liquid column having a proximal portion and a distal portion;a controllable vacuum valve;a vacuum source fluidically connected to the vacuum valve;a controllable vent valve having a vent liquid input;a vent fluid source containing a vent liquid and fluidically connected to the vent valve to retain the vent liquid at the vent fluid input; to the vacuum source through the vacuum valve; and', 'to the vent fluid source through the vent valve;, 'a manifold connected to the catheter, to the vacuum valve, and to the vent valve, the manifold fluidically connecting the proximal portion of the liquid column in the lumen responsive to opening the vacuum valve, the vacuum source is fluidically connected to the liquid column in the lumen; and', 'responsive to opening the vent valve, the vent fluid source is fluidically connected to the liquid column in the lumen,, 'a controller connected to the vacuum valve and the vent valve and configured to selectively open and close the vacuum valve and ...

Modified laryngoscope blade to reduce dental injuries during intubation

The present invention relates to the field of medical devices used in the procedures of orotracheal or nasotracheal intubation. Oral or nasal endotracheal intubation procedures are commonly employed to secure a controlled airway and to deliver inhalant oxygen, anesthetic gases, and other therapeutic agents into the trachea and lungs of human and veterinary patients. Such intubation procedures carry a significant risk of dental injury resulting from contact between the laryngoscope blade used for visualization during intubation. The present invention provides an apparatus to reduce dental injury including a modified laryngoscope blade and a disposable insert which is designed to be received and retained in a single step by the modified laryngoscope blade. The disposable insert may be quickly secured by the user, and reduces both direct pressure and shear forces on the maxillary incisor teeth when the laryngoscope blade is placed in a patient's mouth during intubation.

Actively controllable stent, stent graft, heart valve and method of controlling same

A delivery apparatus can include a handle portion and at least one rotatable drive shaft. The handle portion can have an actuation mechanism with a motor. The rotatable drive shaft can have a proximal end portion and a distal end portion. The proximal end portion of the rotatable drive shaft can be coupled to the motor, and the distal end portion of the rotatable drive shaft can be configured to be releasably coupled to a prosthetic heart valve. The actuation mechanism can be configured to control and monitor expansion of the prosthetic heart valve and to control and monitor torque of the motor.

Balloon cannulae

A catheter has a balloon that overlies a trough in the catheter body such that when the balloon is deflated, the balloon does not protrude beyond the outer circumference of the catheter shaft. The wall of the catheter shaft is thicker along one side than along the remainder of the circumference of the catheter shaft to permit an inflation lumen to be disposed within the thick wall section without increasing the outer diameter of the remaining portion of the circumference.

Methods for controlling the internal circumference of an anatomic orifice or lumen

A method for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural orifice or lumen which is either too large or too small. Implants are disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like.

Balloon Cannulae

A vascular catheter with a circular external diameter, a circular lumen contained within, and an inflatable balloon that overlies a trough in the catheter body such that when the balloon is deflated, the balloon does not protrude beyond the outer circumference of the catheter shaft. The wall of the catheter shaft is thicker along one side than along the remainder of the circumference of the catheter shaft to permit an inflation lumen to be disposed within the thick wall section without increasing the outer diameter of the remaining portion of the circumference. The inflatable balloon is further disposed to maintain the circular lumen of the catheter in the center of flow of the blood vessel in which it is used, maintaining optimal flow. The combination of the circular lumen, circular outer diameter, and recessed balloon trough produces improved hemodynamic flow characteristics within the cannula over existing balloon cannula designs, minimizing flow-related injuries that might cause embolization ...

Figure for attachment to an apparatus for performing medical examinations on children

A figure for attachment to an apparatus for performing examinations on children which includes a toy-like figure attached to and/or at least partially encompassing the examination apparatus for distracting the child prior to or during the examination. The toy-like figure may be any child-attracting figure and may resemble a fictional or real animal, human, or the like. The apparatus with the figure attached will appear less foreign and threatening to children than those which are presently being used. As a result, an examination can be performed more safely and efficiently than was heretofore possible.

Apparatus for implanting surgical devices for controlling the internal circumference of an anatomic orifice or lumen

A system for implanting a surgical device to control the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implants are disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like.

Modified laryngoscope blade to reduce dental injuries during intubation

The present invention relates to the field of medical devices used in the procedures of orotracheal or nasotracheal intubation. Oral or nasal endotracheal intubation procedures are commonly employed to secure a controlled airway and to deliver inhalant oxygen, anesthetic gases, and other therapeutic agents into the trachea and lungs of human and veterinary patients. Such intubation procedures carry a significant risk of dental injury resulting from contact between the laryngoscope blade used for visualization during intubation. The present invention provides an apparatus to reduce dental injury including a modified laryngoscope blade and a disposable insert which is designed to be received and retained in a single step by the modified laryngoscope blade. The disposable insert may be quickly secured by the user, and reduces both direct pressure and shear forces on the maxillary incisor teeth when the laryngoscope blade is placed in a patient's mouth during intubation.

Aspiration thrombectomy system and methods for thrombus removal with aspiration catheter

A clot removal system comprises a catheter, a vacuum source, and a controller. The catheter comprises a proximal end, a distal end, and controller operating parameters and defines a lumen configured to be filled with a liquid column having a proximal portion. The vacuum source is configured to supply vacuum. The controller is configured to carry out a control pattern of turning on and off the vacuum based upon the controller operating parameters and is configured to receive the controller operating parameters in an automatic response to the catheter being operatively connected to at least one of the vacuum source and the controller and, responsive to the connection, to carry out the control pattern to change a level of vacuum at the distal end of the catheter.

ASPIRATION THROMBECTOMY SYSTEM AND METHODS FOR THROMBUS REMOVAL WITH ASPIRATION CATHETER

A clot removal system comprises a catheter, a vacuum source, and a controller. The catheter comprises a proximal end, a distal end, and controller operating parameters and defines a lumen configured to be filled with a liquid column having a proximal portion. The vacuum source is configured to supply vacuum. The controller is configured to carry out a control pattern of turning on and off the vacuum based upon the controller operating parameters and is configured to receive the controller operating parameters in an automatic response to the catheter being operatively connected to at least one of the vacuum source and the controller and, responsive to the connection, to carry out the control pattern to change a level of vacuum at the distal end of the catheter.

Infusion fluid heat exchanger and cartridge

The present invention relates to a system for increasing the temperature of a fluid being infused into a patient's body while the infusion is taking place. The present invention also provides for improved monitoring of air in the infusion system such to prevent the introduction of air into the patient's body receiving the fluid infusion. The present invention also provides for a system pump which provides a variable flow rate that serves a vast amount of infusion needs and purposes. A disposable cartridge in accordance with the present invention will allow for the efficient transfer of heat energy to the fluid being infused into the patient's body. The cartridge will further ensure that deleterious amounts of air will not be introduced into the patient's body.

Modified laryngoscope blade to reduce dental injuries during intubation

The present invention relates to the field of medical devices used in the procedures of orotracheal or nasotracheal intubation. Oral or nasal endotracheal intubation procedures are commonly employed to secure a controlled airway and to deliver inhalant oxygen, anesthetic gases, and other therapeutic agents into the trachea and lungs of human and veterinary patients. Such intubation procedures carry a significant risk of dental injury resulting from contact between the laryngoscope blade used for visualization during intubation. The present invention provides an apparatus to reduce dental injury including a modified laryngoscope blade and a disposable insert which is designed to be received and retained in a single step by the modified laryngoscope blade. The disposable insert may be quickly secured by the user, and reduces both direct pressure and shear forces on the maxillary incisor teeth when the laryngoscope blade is placed in a patient's mouth during intubation.

Actively Controllable Stent, Stent Graft, Heart Valve and Method of Controlling Same

Sealable and repositionable implant devices are provided to increase the ability of endovascular grafts and valves to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes a self-expanding stent of a shape-memory material set to a given shape. The stent has a wall with a portion having a first thickness and a second portion having a thickness greater than the first. The second portion defines a key-hole shaped longitudinal drive orifice. The implant includes a selectively adjustable assembly having adjustable elements and being operable to force a configuration change in at least a portion of the self-expanding stent. The adjustable elements have a part rotatably disposed within the longitudinal drive orifice. 1. A surgical implant , comprising:a self-expanding stent of a shape-memory material set to a given shape, the self-expanding stent having a wall with at least one first portion having a first wall thickness and at least one second portion having a second wall thickness greater than the first wall thickness, the at least one second portion defining a key-hole shaped longitudinal drive orifice; anda selectively adjustable assembly at the self-expanding stent, having adjustable elements, and being operable to force a configuration change in at least a portion of the self-expanding stent, the adjustable elements having a part rotatably disposed within the longitudinal drive orifice.2. The surgical implant according to claim 1 , wherein the key-hole shaped longitudinal drive orifice has an opening facing radially outwards.3. The surgical implant according to claim 1 , wherein the key-hole shaped longitudinal drive orifice has an opening facing radially inwards.4. The surgical implant according to claim 1 , wherein the wall is ...

ASPIRATION THROMBECTOMY SYSTEM AND METHODS FOR THROMBUS REMOVAL WITH ASPIRATION CATHETER

A clot removal system comprises a catheter, a vacuum source, and a controller. The catheter comprises a proximal end, a distal end, and controller operating parameters and defines a lumen configured to be filled with a liquid column having a proximal portion. The vacuum source is configured to supply vacuum. The controller is configured to carry out a control pattern of turning on and off the vacuum based upon the controller operating parameters and is configured to receive the controller operating parameters in an automatic response to the catheter being operatively connected to at least one of the vacuum source and the controller and, responsive to the connection, to carry out the control pattern to change a level of vacuum at the distal end of the catheter.

Left Atrial Appendage Clipping Device and Methods for Clipping the LAA

A surgical clip delivery device end effector that is configured to implant a clip having a pair of opposing clip struts each having a proximal end and a distal end includes a clevis, a pair of jaws connected to the clevis, and a pair of clip-connecting ends configured to removably connect respectively to the pair of clip struts, at least one of the pair of clip-connecting ends connected to at least one of the pair of jaws with two angular degrees of freedom such that, responsive to connection of the clip struts of the clip to the clip-connecting ends, a movement of the jaws in an initial opening action separates the proximal ends of the clip struts before separating the distal ends of the clip struts.

ASPIRATION THROMBECTOMY SYSTEM AND METHODS FOR THROMBUS REMOVAL WITH ASPIRATION CATHETER

A clot removal system comprises a catheter, a vacuum source, and a controller. The catheter comprises a proximal end, a distal end, and controller operating parameters and defines a lumen configured to be filled with a liquid column having a proximal portion. The vacuum source is configured to supply vacuum. The controller is configured to carry out a control pattern of turning on and off the vacuum based upon the controller operating parameters and is configured to receive the controller operating parameters in an automatic response to the catheter being operatively connected to at least one of the vacuum source and the controller and, responsive to the connection, to carry out the control pattern to change a level of vacuum at the distal end of the catheter.

Methods and apparatus for controlling the internal circumference of an anatomic orifice or lumen

An implantable device is provided for controlling at least one of shape and size of an anatomical structure or lumen. An implantable device has an adjustable member configured to adjust the dimensions of the implantable device. An adjustment tool is configured to actuate the adjustable member and provide for adjustment before, during and after the anatomical structure or lumen resumes near normal to normal physiologic function.

Aspiration thrombectomy system and methods for thrombus removal with aspiration catheter

A thrombectomy removal system includes a catheter having a distal end and defining a lumen filled with a liquid column having a proximal portion and a distal portion, a vacuum source, a vent liquid source, and a vacuum and vent control system configured to cyclically connect or disconnect the vacuum source and the vent liquid source to change a level of vacuum at the distal end and substantially prevent forward flow. The vacuum source and the vent source are respectively fluidically connected to the vacuum and vent valves. A manifold connects the proximal portion to the vacuum and vent sources through the valves. Control of the valves prevents forward flow of the distal portion out from the distal end during each cycle. Each cycle can have states including vacuum-only, first double-closed, vent-only, and second double-closed. A time of the double-closed states can be no greater than 30 ms.

Transcutaneous electrostimulator and methods for electric stimulation

A transcutaneous electrostimulation device includes an electrostimulation generator providing at an output a nerve electro stimulation signal, an electronic signal conduit conductively connected to the output of the generator, and an electrode coupler shaped to form fit an ear canal of a human ear and having at least one electrostimulation electrode. The electrode is conductively connected to the electronic signal conduit to receive the nerve electrostimulation signal and is positioned at the electrode coupler to contact tissue within an ear canal and apply the nerve electrostimulation signal to the tissue transcutaneously. An audio source outputs audio signals. The electrode coupler has a speaker receiving the audio signals for output into the ear canal when the electrode coupler is worn. The generator sends the nerve electrostimulation signal to the electrode coupler while the audio signals are output. The generator modulates the nerve electrostimulation signal based upon the audio signals ...

Implantable devices for controlling the internal circumference of an anatomic orifice or lumen

An implantable device for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implants are disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like.

Transcutaneous electrostimulator and methods for electric stimulation

An electrostimulation device includes a computer generating an electrostimulation generator control signal and outputting a music signal, a transcutaneous electrostimulation generator, an electronic signal conduit, and an electrode coupler. The generator wirelessly receives the generator control signal and the music signal, generates a nerve electrostimulation signal dependent upon the generator control signal, and wirelessly outputs the nerve electrostimulation signal at the stimulation output and the music signal at an audio output. The coupler fits in an ear canal, has a speaker connected to the audio output to output the music signal into the ear canal when worn, and has electrostimulation electrodes wirelessly connected to the stimulation output through the electronic signal conduit to receive the nerve electrostimulation signal and positioned to contact tissue within the canal to transcutaneously apply the nerve electrostimulation signal thereto. The coupler supplies the nerve electrostimulation ...

Multiple-firing suture fixation device and methods for using and manufacturing same

A multiple-firing crimp device comprises crimps, a shaft, a crimp movement assembly, and a snare. Each crimp has an internal hollow. The shaft has a distal crimping location, an exterior surface, and an interior with the clips stacked therein, the crimps moving therein along a longitudinal axis. The shaft defines a lateral opening proximal to the crimping location and communicates the interior to the environment outside the exterior surface. The crimp movement assembly within the shaft delivers the first crimp to the distal crimping location by moving the first crimp longitudinally from a first proximal position into the distal crimping location and returning to a second proximal position without the first crimp. The snare pulls at least one cord from distal of the first crimp through the first crimp and through a portion of the shaft and out the side of the shaft through the lateral opening.

Recapturable left atrial appendage clipping device and methods for recapturing a left atrial appendage clip

A recapturable external LAA exclusion clip system includes a clip comprising first and second clip struts, at least one of the struts having a connector interface comprising a first portion of a lock, and a delivery device comprising a handle and an end effector. The handle comprises jaw and lock controls. The end effector is connected to the handle and comprises a clevis and first and second jaws. The jaws are connected to the clevis and operatively connected to the jaw control to actively articulate at least one of the jaws with respect to the other. At least one of the jaws has a connector comprising a second portion of the lock operatively connected to the lock control to removably lock with the first portion of the lock. The first and second portions of the lock have a locked state and are configured to unlock the locked state upon actuation of the lock control.

Recapturable Left Atrial Appendage Clipping Device and Methods for Recapturing a Left Atrial Appendage Clip

A recapturable external LAA exclusion clip system includes a clip comprising first and second clip struts, at least one of the struts having a connector interface comprising a first portion of a lock, and a delivery device comprising a handle and an end effector. The handle comprises jaw and lock controls. The end effector is connected to the handle and comprises a clevis and first and second jaws. The jaws are connected to the clevis and operatively connected to the jaw control to actively articulate at least one of the jaws with respect to the other. At least one of the jaws has a connector comprising a second portion of the lock operatively connected to the lock control to removably lock with the first portion of the lock. The first and second portions of the lock have a locked state and are configured to unlock the locked state upon actuation of the lock control. 1. (canceled)2. An external left atrial appendage (LAA) exclusion clip recapture system , comprising: a first clip strut comprising a first connector interface; and', 'a second clip strut comprising a second connector interface, at least one of the first and second connector interfaces comprising a first portion of a lock; and, 'an LAA exclusion clip comprising a handle comprising a jaw control and a lock control; and', a clevis; and', connected to the clevis;', 'operatively connected to the jaw control to actively articulate at least one of the first and second jaws with respect to the other;', 'having respective first and second connectors, the first connector of the first jaw having a given length and the second connector of the second jaw having a length different from the given length; and', 'at least one of the first and second connectors comprising a second portion of the lock and being operatively connected to the lock control to removably lock with the first portion of the lock., 'first and second jaws], 'an end effector connected to the handle and comprising], 'a delivery and recapture device ...

Multiple-Firing Crimp Device and Methods for Using and Manufacturing Same

A multiple-firing crimp device comprises crimps, a shaft, a crimp movement assembly, and a snare. Each crimp has an internal hollow. The shaft has a distal crimping location, an exterior surface, and an interior with the clips stacked therein, the crimps moving therein along a longitudinal axis. The shaft defines a lateral opening proximal to the crimping location and communicates the interior to the environment outside the exterior surface. The crimp movement assembly within the shaft delivers the first crimp to the distal crimping location by moving the first crimp longitudinally from a first proximal position into the distal crimping location and returning to a second proximal position without the first crimp. The snare pulls at least one cord from distal of the first crimp through the first crimp and through a portion of the shaft and out the side of the shaft through the lateral opening. 1. A multiple-firing crimp device , comprising:a plurality of crimps each having an internal hollow; [ a distal crimping location;', 'an exterior surface; and', 'an interior in which is stacked the plurality of crimps to define a first crimp, the crimps moving therein along a longitudinal axis; and, 'having, 'defining a lateral opening proximal to the crimping location and communicating between the interior and the environment outside the exterior surface;, 'a hollow shafta crimp movement assembly within the interior of the shaft and delivering the first crimp to the distal crimping location by moving the first crimp longitudinally from a first proximal position into the distal crimping location and returning to a second proximal position without the first crimp; anda snare that pulls at least one cord from distal of the first crimp through the first crimp and through a portion of the shaft and out the side of the shaft through the lateral opening.2. The crimp device according to claim 1 , which further comprises a snare movement assembly: to pass through the internal hollow of ...

Renewable energy system and methods for creating renewable energy

A renewable energy device includes a wheel rotatably mounted on a base to spin about an axis of rotation and having a plurality of hollow, barbell-shaped fluid subassemblies fixed symmetrically about the axis. The fluid subassemblies each have a longitudinal axis radiating away from the axis of rotation, a hollow outer end defining a circular, ring-shaped, outer travel path when rotated about the axis of rotation, a hollow inner end defining a circular, ring-shaped, travel path disposed within the outer travel path when rotated about the axis of rotation, a hollow conduit fluidically connecting the outer and inner ends to define an interior cavity, and a room-temperature-boiling-point fluid disposed in the interior cavity. Inner and outer thermal variance subassemblies cover approximately half of respective ones of the inner and outer travel paths on at least one side of the wheel.

ASPIRATION THROMBECTOMY SYSTEM AND METHODS FOR THROMBUS REMOVAL WITH ASPIRATION CATHETER

A clot removal system comprises a catheter, a vacuum source, and a controller. The catheter comprises a proximal end, a distal end, and controller operating parameters and defines a lumen configured to be filled with a liquid column having a proximal portion. The vacuum source is configured to supply vacuum. The controller is configured to carry out a control pattern of turning on and off the vacuum based upon the controller operating parameters and is configured to receive the controller operating parameters in an automatic response to the catheter being operatively connected to at least one of the vacuum source and the controller and, responsive to the connection, to carry out the control pattern to change a level of vacuum at the distal end of the catheter.

Rapid infusion system

A rapid infusion system for rapidly delivering blood and/or volume expanding fluid to a patient, said rapid infusion device comprising in combination: a portion which includes an adjustable drive means and related control means therefor, and a portion which includes components that come into contact with the fluid infused to the patient, and optionally wherein said system can be portable.

Transcutaneous electrostimulator and methods for electric stimulation

An electrostimulation device comprising an electrode coupler configured as an earbud, the earbud shaped to form fit inside an ear canal of a human ear and composed of a pliable material that conforms to the ear canal when inserted therein, the pliable material forming at least two electrostimulation electrodes, each electrostimulation electrode conductively connected to a conductive lead adapted to receive a nerve electrostimulation signal, and the earbud adapted to transmit the nerve electrostimulation signal through the electrostimulation electrodes from the conductive leads to tissue within the ear canal when disposed therein.

Left atrial appendage clipping device and methods for clipping the LAA

An external LAA exclusion clip comprises a clipping assembly comprising first and second opposing clip struts each of the clip struts having a tissue-contacting surface and first and second bias surfaces, a bias assembly connecting the first clip strut to the second clip strut to align the first and second clip struts in a strut plane passing through the tissue-contacting surface. The bias assembly comprises at least one first bias spring connected to the first bias surface of the first clip strut and to the first bias surface of the second clip strut and at least one second bias spring connected to the second bias surface of the first clip strut and the second bias surface of the second clip strut. The first bias spring and the second bias spring are configured to permit movement of the first and second clip struts in the strut plane.

ACTIVELY CONTROLLABLE STENT, STENT GRAFT, HEART VALVE AND METHOD OF CONTROLLING SAME

A delivery apparatus can include a handle portion and at least one rotatable drive shaft. The handle portion can have an actuation mechanism with a motor. The rotatable drive shaft can have a proximal end portion and a distal end portion. The proximal end portion of the rotatable drive shaft can be coupled to the motor, and the distal end portion of the rotatable drive shaft can be configured to be releasably coupled to a prosthetic heart valve. The actuation mechanism can be configured to control and monitor expansion of the prosthetic heart valve and to control and monitor torque of the motor. 1. A delivery apparatus , comprising:a handle portion having an actuation mechanism, wherein the actuation mechanism includes a motor; andat least one rotatable drive shaft having a proximal end portion and a distal end portion, wherein the proximal end portion is coupled to the motor, and the distal end portion is configured to be releasably coupled to a prosthetic heart valve,wherein the actuation mechanism is configured to control and monitor expansion of the prosthetic heart valve and to control and monitor torque of the motor.2. The delivery apparatus of claim 1 , wherein the actuation mechanism further comprises a torque limiting member configured to limit an electrical current of the motor.3. The delivery apparatus of claim 1 , wherein the actuation mechanism further comprises a clutch mechanism configured to limit the torque transmitted to the drive shaft from the motor.4. The delivery apparatus of claim 1 , wherein the actuation mechanism further comprises a gear assembly coupled to the motor and the drive shaft and configured to transfer rotational movement of the motor to the drive shaft.5. The delivery apparatus of claim 4 , wherein the at least one drive shaft is a plurality of drive shafts claim 4 , the motor includes an output shaft having a first gear claim 4 , and the gear assembly includes a second gear claim 4 , a connecting shaft claim 4 , a third gear ...

Multiple-Firing Suture Fixation Device and Methods for Using and Manufacturing Same

A multiple-firing crimp device comprises crimps, a shaft, a crimp movement assembly, and a snare. Each crimp has an internal hollow. The shaft has a distal crimping location, an exterior surface, and an interior with the clips stacked therein, the crimps moving therein along a longitudinal axis. The shaft defines a lateral opening proximal to the crimping location and communicates the interior to the environment outside the exterior surface. The crimp movement assembly within the shaft delivers the first crimp to the distal crimping location by moving the first crimp longitudinally from a first proximal position into the distal crimping location and returning to a second proximal position without the first crimp. The snare pulls at least one cord from distal of the first crimp through the first crimp and through a portion of the shaft and out the side of the shaft through the lateral opening. 1. A multiple-firing crimp device , comprising:a plurality of crimps each having an internal hollow; [ a distal crimping location;', 'an exterior surface; and', 'an interior in which is stacked the plurality of crimps to define a first crimp, the crimps moving therein along a longitudinal axis; and, 'having, 'defining a lateral opening proximal to the crimping location and communicating between the interior and the environment outside the exterior surface;, 'a hollow shafta crimp movement assembly within the interior of the shaft and delivering the first crimp to the distal crimping location by moving the first crimp longitudinally from a first proximal position into the distal crimping location and returning to a second proximal position without the first crimp; anda snare that pulls at least one cord from distal of the first crimp through the first crimp and through a portion of the shaft and out the side of the shaft through the lateral opening.2. The crimp device according to claim 1 , which further comprises a snare movement assembly: to pass through the internal hollow of ...

Actively controllable stent, stent graft, heart valve and method of controlling same

An assembly includes a prosthetic heart valve and a delivery apparatus. The prosthetic heart valve has a plurality of pivotably connected struts and one or more adjustable elements rotatably coupled to the struts. Rotating the adjustable elements in a first direction relative to the struts radially expands the prosthetic heart valve. Rotating the adjustable elements in a second direction relative to the struts radially contracts the prosthetic heart valve. The delivery apparatus includes one or more motors, one or more drive wires coupled to the motors, and a memory. The drive wires are coupled to the adjustable elements of the prosthetic heart valve. The motors are configured to rotate the drive wires and the adjustable elements to expand and contract the prosthetic heart valve. The memory is configured for storing one or more characteristics of the motors, the drive wires, or the prosthetic heart valve.

ASPIRATION THROMBECTOMY SYSTEM AND METHODS FOR THROMBUS REMOVAL WITH ASPIRATION CATHETER

A clot removal system comprises a catheter, a vacuum source, and a controller. The catheter comprises a proximal end, a distal end, and controller operating parameters and defines a lumen configured to be filled with a liquid column having a proximal portion. The vacuum source is configured to supply vacuum. The controller is configured to carry out a control pattern of turning on and off the vacuum based upon the controller operating parameters and is configured to receive the controller operating parameters in an automatic response to the catheter being operatively connected to at least one of the vacuum source and the controller and, responsive to the connection, to carry out the control pattern to change a level of vacuum at the distal end of the catheter.

Left atrial appendage clipping device and methods for clipping the LAA

An LAA exclusion system includes a clip comprising first and second separate clip struts, and a bias device comprising spring portions, and a delivery device having clip-contacting ends. The first clip strut has a first proximal end. The second clip strut has a second proximal end adjacent the first proximal end. The clip struts together define a first exterior surface and an opposing second exterior surface. The first spring portion connects the first clip strut to the second clip strut along the first exterior surface and the second spring portion connects the first clip strut to the second clip strut along the second exterior surface. The spring portions define therebetween a strut-securing area at the first and second proximal ends. The clip-contacting ends are configured to removably connect to the proximal ends of the clip struts through the strut-securing area.

TRANSCUTANEOUS ELECTROSTIMULATOR AND METHODS FOR ELECTRIC STIMULATION

An electrostimulation device includes a computer generating an electrostimulation generator control signal and outputting a music signal, a transcutaneous electrostimulation generator, an electronic signal conduit, and an electrode coupler. The generator receives the generator control signal and the music signal, generates a nerve electrostimulation signal dependent upon the generator control signal, and outputs the nerve electrostimulation signal at the stimulation output and the music signal at an audio output. The coupler fits in an ear canal, has a speaker connected to the audio output to output the music signal into the ear canal when worn, and has electrostimulation electrodes conductively connected to the stimulation output through the electronic signal conduit to receive the nerve electrostimulation signal and positioned to contact tissue within the canal to transcutaneously apply the nerve electrostimulation signal thereto. The coupler supplies the nerve electrostimulation signal while music outputs from the speaker. 1. An electrostimulation device , comprising:a computer generating an electrostimulation generator control signal and outputting a music signal; receiving the electrostimulation generator control signal and the music signal;', 'generating a nerve electrostimulation signal dependent upon the electrostimulation generator control signal and outputting the nerve electrostimulation signal at the stimulation output; and', 'outputting the music signal at an audio output;, 'a transcutaneous electrostimulation generator having a stimulation output and an audio output andan electronic signal conduit conductively connected to the stimulation output and to the audio output; and having at least one audio speaker connected to the audio output and outputting the music signal into the ear canal when worn;', conductively connected to the stimulation output through the electronic signal conduit to receive the nerve electrostimulation signal; and', 'positioned to ...

Portable electronic device

BALLOON CANNULAE

A vascular catheter with a circular external diameter, a circular lumen contained within, and an inflatable balloon that overlies a trough in the catheter body such that when the balloon is deflated, the balloon does not protrude beyond the outer circumference of the catheter shaft. The wall of the catheter shaft is thicker along one side than along the remainder of the circumference of the catheter shaft to permit an inflation lumen to be disposed within the thick wall section without increasing the outer diameter of the remaining portion of the circumference. The inflatable balloon is further disposed to maintain the circular lumen of the catheter in the center of flow of the blood vessel in which it is used, maintaining optimal flow. The combination of the circular lumen, circular outer diameter, and recessed balloon trough produces improved hemodynamic flow characteristics within the cannula over existing balloon cannula designs, minimizing flow-related injuries that might cause embolization ...

ASPIRATION THROMBECTOMY SYSTEM AND METHODS FOR THROMBUS REMOVAL WITH ASPIRATION CATHETER

A clot removal system comprises a catheter, a vacuum source, and a controller. The catheter comprises a proximal end, a distal end, and controller operating parameters and defines a lumen configured to be filled with a liquid column having a proximal portion. The vacuum source is configured to supply vacuum. The controller is configured to carry out a control pattern of turning on and off the vacuum based upon the controller operating parameters and is configured to receive the controller operating parameters in an automatic response to the catheter being operatively connected to at least one of the vacuum source and the controller and, responsive to the connection, to carry out the control pattern to change a level of vacuum at the distal end of the catheter.

Recapturable Left Atrial Appendage Clipping Device and Methods for Recapturing a Left Atrial Appendage Clip

A recapturable external LAA exclusion clip system includes a clip comprising first and second clip struts, at least one of the struts having a connector interface comprising a first portion of a lock, and a delivery device comprising a handle and an end effector. The handle comprises jaw and lock controls. The end effector is connected to the handle and comprises a clevis and first and second jaws. The jaws are connected to the clevis and operatively connected to the jaw control to actively articulate at least one of the jaws with respect to the other. At least one of the jaws has a connector comprising a second portion of the lock operatively connected to the lock control to removably lock with the first portion of the lock. The first and second portions of the lock have a locked state and are configured to unlock the locked state upon actuation of the lock control. 1. A recapturable external left atrial appendage (LAA) exclusion clip system , comprising: a first clip strut; and', 'a second clip strut, at least one of the first and second clip struts having a connector interface comprising a first portion of a lock; and, 'an LAA exclusion clip comprising a handle comprising a jaw control and a lock control;', a clevis; and', connected to the clevis; and', 'operatively connected to the jaw control to actively articulate at least one of the first and second jaws with respect to the other, at least one of the first and second jaws having a connector comprising a second portion of the lock operatively, connected to the lock control to removably lock with the first portion of the lock; and, 'first and second jaws], 'an end effector connected to the handle and comprising, to unlock the locked state upon actuation of the lock control; and', 'after having been released, to automatically re-enter the locked state as the first and second portions, of the lock are moved back together., 'the first and second portions of the lock having a locked state and being configured], 'a ...

Aspiration thrombectomy system and methods for thrombus removal with aspiration catheter

A clot removal system includes a catheter having proximal and distal ends and defining a lumen configured to be filled with a liquid column having a proximal portion, a vacuum pump supplying vacuum, a vent container holding vent liquid, a vent valve configured to fluidically communicate with the vent liquid and with the proximal portion of the liquid column at the proximal end of the catheter, a vacuum valve configured to fluidically communicate with the vacuum and with the proximal portion of the liquid column at the proximal end of the catheter, and a controller configured to carry out a pre-determined pattern of opening and closing the vent and vacuum valves to change a level of vacuum at the distal end and, while changing the level of vacuum at the distal end, to substantially prevent forward flow of the liquid at a distal end of the liquid column.

Renewable energy system and methods for creating renewable energy

A renewable energy device includes a wheel rotatably mounted on a base to spin about an axis of rotation and having a plurality of hollow, barbell-shaped fluid subassemblies fixed symmetrically about the axis. The fluid subassemblies each have a longitudinal axis radiating away from the axis of rotation, a hollow outer end defining a circular, ring-shaped, outer travel path when rotated about the axis of rotation, a hollow inner end defining a circular, ring-shaped, travel path disposed within the outer travel path when rotated about the axis of rotation, a hollow conduit fluidically connecting the outer and inner ends to define an interior cavity, and a room-temperature-boiling-point fluid disposed in the interior cavity. Inner and outer thermal variance subassemblies cover approximately half of respective ones of the inner and outer travel paths on at least one side of the wheel.

Aspiration thrombectomy system and methods for thrombus removal with aspiration catheter

A clot removal system comprises a catheter, a vacuum source, and a controller. The catheter comprises a proximal end, a distal end, and controller operating parameters and defines a lumen configured to be filled with a liquid column having a proximal portion. The vacuum source is configured to supply vacuum. The controller is configured to carry out a control pattern of turning on and off the vacuum based upon the controller operating parameters and is configured to receive the controller operating parameters in an automatic response to the catheter being operatively connected to at least one of the vacuum source and the controller and, responsive to the connection, to carry out the control pattern to change a level of vacuum at the distal end of the catheter.

Recapturable left atrial appendage clipping device and methods for recapturing a left atrial appendage clip

A recapturable external LAA exclusion clip system includes a clip comprising first and second clip struts, at least one of the struts having a connector interface comprising a first portion of a lock, and a delivery device comprising a handle and an end effector. The handle comprises jaw and lock controls. The end effector is connected to the handle and comprises a clevis and first and second jaws. The jaws are connected to the clevis and operatively connected to the jaw control to actively articulate at least one of the jaws with respect to the other. At least one of the jaws has a connector comprising a second portion of the lock operatively connected to the lock control to removably lock with the first portion of the lock. The first and second portions of the lock have a locked state and are configured to unlock the locked state upon actuation of the lock control.

Rapid infusion system

A rapid infusion system for the intravenous delivery of fluids at standard and rapid flow rates. The system includes a pump assembly, a drive assembly to power the pump, and a fluid containment system that keeps the infused fluid out of direct contact with the pump assembly and that is preferably disposable and removable. In one embodiment the drive assembly includes a differential drive that interacts with more than one motor. In one embodiment, the pump assembly includes a roller pump and the pump chamber is a collapsible, preformed tube that is preferably attached to a pump cartridge frame. Optionally, the system includes a self-leveling drip chamber and the fluid containment system is disposable and includes a pump cartridge containing the drip chamber and the pump chamber, I.V. tubing, outlet infusion tubing, and a heater cartridge.

TRANSCUTANEOUS ELECTROSTIMULATOR AND METHODS FOR ELECTRIC STIMULATION

An electrostimulation device comprising an electrode coupler configured as an earbud, the earbud shaped to form fit inside an ear canal of a human ear and composed of a pliable material that conforms to the ear canal when inserted therein, the pliable material forming at least two electrostimulation electrodes, each electrostimulation electrode conductively connected to a conductive lead adapted to receive a nerve electrostimulation signal, and the earbud adapted to transmit the nerve electrostimulation signal through the electrostimulation electrodes from the conductive leads to tissue within the ear canal when disposed therein.

Renewable Energy System and Methods for Creating Renewable Energy

A renewable energy device includes a wheel rotatably mounted on a base to spin about an axis of rotation and having a plurality of hollow, barbell-shaped fluid subassemblies fixed symmetrically about the axis. The fluid subassemblies each have a longitudinal axis radiating away from the axis of rotation, a hollow outer end defining a circular, ring-shaped, outer travel path when rotated about the axis of rotation, a hollow inner end defining a circular, ring-shaped, travel path disposed within the outer travel path when rotated about the axis of rotation, a hollow conduit fluidically connecting the outer and inner ends to define an interior cavity, and a room-temperature-boiling-point fluid disposed in the interior cavity. Inner and outer thermal variance subassemblies cover approximately half of respective ones of the inner and outer travel paths on at least one side of the wheel. 1. A renewable energy device , comprising:a base; a longitudinal axis radiating away from the axis of rotation;', 'a hollow outer end defining a circular, ring-shaped, outer travel path when rotated about the axis of rotation;', 'a hollow inner end defining a circular, ring-shaped, travel path disposed within the outer travel path when rotated about the axis of rotation;', 'a hollow conduit fluidically connecting the outer and inner ends to define an interior cavity; and', 'a room-temperature-boiling-point fluid disposed in the interior cavity;, 'a wheel rotatably mounted on the base to spin about an axis of rotation and comprising a plurality of hollow, barbell-shaped fluid subassemblies fixed to the wheel symmetrically about the axis of rotation, the fluid subassemblies each havingan outer thermal variance subassembly covering approximately half of the outer travel path on at least one side of the wheel; andan inner thermal variance subassembly covering approximately half of the inner travel path on at least the one side of the wheel.2. The device according to claim 1 , wherein the ...

Portable electronic device

Left Atrial Appendage Clipping Device and Methods for Clipping the LAA

An external LAA exclusion clip comprises a clipping assembly comprising first and second opposing clip struts each of the clip struts having a tissue-contacting surface and first and second bias surfaces, a bias assembly connecting the first clip strut to the second clip strut to align the first and second clip struts in a strut plane passing through the tissue-contacting surface. The bias assembly comprises at least one first bias spring connected to the first bias surface of the first clip strut and to the first bias surface of the second clip strut and at least one second bias spring connected to the second bias surface of the first clip strut and the second bias surface of the second clip strut. The first bias spring and the second bias spring are configured to permit movement of the first and second clip struts in the strut plane. 1. An external left atrial appendage (LAA) exclusion clip , comprising: a tissue-contacting surface; and', 'first and second bias surfaces;, 'a clipping assembly comprising first and second opposing clip struts each of the clip struts having at least one first bias spring connected to the first bias surface of the first clip strut and to the first bias surface of the second clip strut; and', 'at least one second bias spring connected to the second bias surface of the first clip strut and the second bias surface of the second clip strut; and, 'a bias assembly connecting the first clip strut to the second clip strut to align the first and second clip struts in a strut plane passing through the tissue-contacting surface, the bias assembly comprisingthe at least one first bias spring and the at least one second bias spring being configured to permit movement of the first and second clip struts in the strut plane.2. The clip according to claim 1 , wherein:the first clip strut has a first proximal end and a first distal end;the second clip strut has a second proximal end and a second distal end; an intermediate position at the first bias ...

TRANSCUTANEOUS ELECTROSTIMULATOR AND METHODS FOR ELECTRIC STIMULATION

An electrostimulation device comprises a hand-held electrostimulation generator receiving an input music signal and providing at an output a nerve electrostimulation signal modulated by the music signal, an electronic signal conduit having conductive leads conductively connected to the output of the electrostimulation generator, and an electrode coupler comprising an earbud. The earbud is shaped to form fit inside an ear canal of a human ear and composed of a pliable material conforming to the ear canal when inserted therein, the pliable material forming at least two electrostimulation electrodes conductively connected to a respective one of the conductive leads of the electronic signal conduit to receive the nerve electrostimulation signal and transmitting the nerve electrostimulation signal to at least two different, electrically conductive exterior surface portions of the pliable material and transcutaneously applying the nerve electrostimulation signal from the conductive leads to tissue within the ear canal when disposed therein. 1. An electrostimulation device , comprising: receiving an input music signal; and', 'providing at an output a nerve electrostimulation signal modulated by the input music signal;, 'a hand-held electrostimulation generatoran electronic signal conduit having at least two conductive leads conductively connected to the output of the electrostimulation generator; and shaped to form fit inside an ear canal of a human ear; and', conductively connected to a respective one of the at least two conductive leads of the electronic signal conduit to receive the nerve electrostimulation signal; and', 'transmitting the nerve electrostimulation signal to at least two different, electrically conductive exterior surface portions of the pliable material and transcutaneously applying the nerve electrostimulation signal from the at least two conductive leads to tissue within the ear canal when disposed therein., 'composed of a pliable material that ...

METHOD OF POST-OPERATIVE ADJUSTMENT FOR MITRAL VALVE IMPLANT

The present invention is directed to a mechanism and procedure for adjusting a cardiac implant during the early post-operative period, such as, for example, the first 2-5 days after surgery. During the implant procedure, an adjustment tool is releasably attached to the adjustable implant. The adjustment tool remains connected to the implant following the procedure and extends from the patient's body to allow for post-operative adjustment under normal beating heart conditions. Once the implant is adjusted, the adjustment tool is configured to release from the implant and be removed from the patient's body without requiring access to the patient's heart. 1. A method of performing a post-operative adjustment of the internal dimensions of an annulus of a patient's heart , said method comprising the steps of:arresting the heart and creating a left atriotomy;securing an adjustable implant ring to the tissue adjacent the annulus;creating a right atriotomy and advancing the adjustment tool through the heart's atrial septum into the left atrium;releasably attaching the adjustment tool to the adjustable implant ring so as to allow for adjustment of the ring dimensions using the tool;closing the left atriotomy;resuming blood flow through the heart; andadjusting the adjustable implant ring using the adjustment tool from outside the patient's body.2. A method of performing a post-operative adjustment of the internal dimensions of an annulus of a patient's heart , said method comprising the steps of:arresting the heart and creating an atriotomy;securing an adjustable implant ring to the tissue adjacent the annulus;creating an incision in the pulmonary vein and advancing an adjustment tool into The left atrium;releasably attaching the adjustment tool to the adjustable implant ring so as to allow for adjustment of the ring dimensions using the tool;closing the atriotomy;resuming blood flow through the heart; andadjusting the adjustable implant ring using the adjustment tool from ...

Surgical Implant Devices and Methods for Their Manufacture and Use

A sealable vascular system includes an endovascular implant to be delivered in a compressed or folded state to an implantation site. The endovascular implant includes a tubular implant body and a sealable circumferential collar at said tubular implant body and including a variable sealing device and a control lead traversing from said variable sealing device to a user for controlling said variable sealing device by the user, said variable sealing device and said control lead being cooperatively operable to reversibly expand and contract said sealable circumferential collar such that said sealable circumferential collar is circumferentially adjustable during deployment thereof to achieve a repositionable fluid-tight seal between said sealable circumferential collar and the internal walls of the implantation site.

INFLATABLE MINIMALLY INVASIVE SYSTEM FOR DELIVERING AND SECURING AN ANNULAR IMPLANT

A delivery device for an annular implant that includes a balloon expansion mechanism and an annular implant having an adjustable dimension. The balloon expansion mechanism includes an inflation tube attached to a non-occluding balloon collar which is supported by trusses radially extending from a trocar. The annular implant further includes a flexible ring core, contiguous coiled spacers, and anchoring blocks. The flexible ring core is adjusted via a cinching mechanism. The anchoring blocks are spaced along the ring core by the contiguous coiled spacers, which keeps the distance between each pair of anchoring blocks equidistant as the ring core diameter is manipulated by the device user. The annular implant can also include gunbarrel elements housed in the trocar. Each gunbarrel element contains a gunbarrel pusher which drives an attachment element into the annular implant and annular tissue. 1. A delivery device for an annular implant comprising:a balloon expansion mechanism, wherein the balloon expansion mechanism comprises a hollow catheter attached to an inflation tube whereby a gas or liquid is fed through said inflation tube and a non-occluding balloon collar attached to the inflation tube to provide for expansion of the balloon collar, wherein the balloon collar is supported by a plurality of trusses radially extending from a trocar;an annular implant having an adjustable dimension removably mounted around the non-occluding balloon collar, wherein the annular implant is adjustable through at least one cinching cord; anda cinching mechanism attached to the annular implant, wherein the cinching mechanism reshapes the annular implant to conform to the size and shape of the annulus via the at least one cinching cord.2. The delivery device of claim 1 , wherein the annular implant includes a flexible ring core and wherein the flexible ring core is adjustable through two cinching cords.3. The delivery device of claim 1 , wherein the cinching mechanism comprises:a ...

User Interface and Controls for a Pump Device

A pump system selectably and dynamically controls the flow rate of a fluid being delivered to a patient's body over a wide range of flow rates. The pump system includes an infusion tubing, a pumping mechanism, a motor drive assembly in mechanical communication with the pumping mechanism, a user input control, and an electronic controller in electrical communication with and at least partially controlling the motor drive assembly. The electronic controller include a digital signal processing controller in electrical communication with the motor drive assembly that is configured to receive a signal from the user input control and to cause power to be supplied to the motor drive assembly in response at least partially to the signal from the user input control. The pump system may selectably deliver fluid at rates from about 1 milliliter per hour to at least about 3000 milliliters per minute. 1. A pump system , comprising:an infusion tubing for delivering a fluid;a motor driven pump in mechanical communication with the infusion tubing and configured to pump the fluid through the infusion tubing;a heat exchanger cartridge in fluid communication with the infusion tubing and removably coupled to at least one thermal element for heating or cooling the fluid;a central controller in electrical communication with the motor driven pump and the at least one thermal element; anda user interface in electrical communication with the central controller;wherein the central controller is configured to adjust at least one of a flow rate, a temperature, and a pressure of the fluid in response to selection of an input of the user interface.2. The pump system of claim 1 , wherein the user interface comprises a prime input claim 1 , and wherein the central controller is configured to prime the infusion tubing by causing the motor driven pump to pump the fluid through the infusion tubing at a predetermined flow rate in response to selection of the prime input.3. The pump system of claim 2 , ...

Post-operative adjustment tool, minimally invasive attachment apparatus, and adjustable tricuspid ring

An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ.

IMPLANTABLE DEVICES FOR CONTROLLING THE SIZE AND SHAPE OF AN ANATOMICAL STRUCTURE OR LUMEN

An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit he implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ. 1. An implantable device system for controlling at least one of the shape and size of an anatomical structure or lumen , comprising:an implantable device adapted for attachment to an anatomical structure or lumen, said implantable device having a first band and a second band and an adjustable member configured to both increase and decrease the dimensions of the implantable device, said adjustable member configured to receive an adjustment tool;a torqueable adjustment tool configured to provide adjustment of the dimensions of the implantable device, wherein adjustment of said adjustable member adjusts the size of the implant device generally in a preferred dimension.2. The system of claim 1 , wherein the first band and the second band are overlappable.3. The system of claim 1 , wherein the first band and the second band are slidable relative to each other.4. The system of claim 1 , wherein the adjustable member is configured to pull the first band and the second band towards and away from each other.5. The system of claim 1 , wherein the at least one of said first and second bands has portions of varying durometer.6. The system of claim 1 , wherein the implantable device comprise a prosthetic heart valve.7. The system of claim 6 , wherein the prosthetic heart valve comprises an annuloplasty ring.8. An implantable device having an adjustable size or shape comprising:a first band including a terminal end having a plurality of ...

METHODS FOR CONTROLLING THE INTERNAL CIRCUMFERENCE OF AN ANATOMIC ORIFICE OR LUMEN

A method for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural orifice or lumen which is either too large or too small. Implants are disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like. 1. A method of implanting a foldable prosthetic annular ring to a patient's heart comprising:providing a prosthetic annular ring folded inside a catheter for delivery to the patient's heart;inserting the catheter through an anatomic passageway into a native recipient anatomic site of the patient's heart;expelling the prosthetic annular ring from the catheter whereby the prosthetic annular ring has an unfolded configuration;securing the prosthetic annular ring when in the unfolded configuration to adjacent tissue, said securing including application of external force to allow the prosthetic annular ring to attach to the adjacent tissue using a mechanical tissue interface system thereby holding the prosthetic annular ring in place; and removing the catheter from the anatomic passageway.2. The method of claim 1 , wherein the mechanical tissue interface system comprises a plurality of retention barbs claim 1 , said application of external force engages the retention barbs into the adjacent tissue.3. The method of claim 1 , wherein said expelling comprises use of support arms attached to the prosthetic annular ring that expand to deploy said prosthetic annular ring from a folded configuration to an unfolded configuration having a radial dimension.4. The method of claim 1 , wherein said prosthetic annular ...

METHODS AND DEVICES FOR MODULATION OF HEART VALVE FUNCTION

Methods and devices for modulating heart valve function are provided. In the subject methods, a heart valve is first in structurally modified. Blood flow through the structurally modified heart valve is then monitored, and the heart is paced in response to the monitored blood flow. Also provided are devices, systems and kits that find use in practicing the subject methods. The subject methods find use in a variety of applications. 1. A method of modulating the function of a cardiac valve in a heart , said method comprising:structurally altering said cardiac valve;monitoring blood flow through said structurally altered cardiac valve;andpacing said heart in response to said monitoring to modulate function of said cardiac valve.2. The method according to claim 1 , wherein said modulating results in an improvement in said cardiac valve function.3. The method according to claim 2 , wherein said cardiac valve is a mitral valve.4. The method according to claim 3 , wherein said structurally altering comprises performing an annuloplasty procedure on said mitral valve.5. The method according to claim 4 , wherein said annuloplasty procedure employs an implantable annuloplasty device.6. The method according to claim 5 , wherein said annuloplasty device is an interstitial device.7. The method according to claim 1 , wherein said monitoring employs an implanted blood flow velocity measuring device.8. The method according to claim 7 , wherein said blood flow velocity measuring device is a sonic device.9. The method according to claim 7 , wherein said blood flow velocity measuring device is an optical device.10. The method according to claim 7 , wherein said blood flow velocity measuring device is a thermal device.11. The method according to claim 7 , wherein said blood flow velocity measuring device is an electromagnetic device.12. The method according to claim 7 , wherein said blood flow velocity measuring device is in operational communication with an implanted cardiac pacing ...

IMPLANTABLE DEVICES FOR CONTROLLING THE INTERNAL CIRCUMFERENCE OF AN ANATOMIC ORIFICE OR LUMEN

An implantable device for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implants area disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive producers and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like. 1. An implantable device system for controlling at least one of the shape and size of an anatomical orifice or lumen , comprising:an adjustable implantable device adapted for attachment to an anatomical orifice or lumen, said implantable device including an adjustable member configured to adjust at least one of the shape and size of the implantable device; andan adjustment tool configured to be releasably connected to the adjustable member such that the adjustment tool can be used to activate and control adjustment of the implantable device;wherein the adjustment member and the adjustment tool are configured to be attached and subsequently reattached to each other when the implantable device is positioned in situ to the anatomical orifice or lumen.2. The system of claim 1 , wherein the adjustable member includes an adjustment element configured for releasably connecting and reconnecting the adjustment tool to the adjustable member.3. The system of claim 1 , wherein the adjustable implant device comprises a prosthetic heart valve.4. The system of claim 3 , wherein the adjustable implantable device comprises an annuloplasty ring.5. The system of claim 3 , wherein the adjustment tool is mechanically connected to the adjustable member.6. An adjustable implantable device system for an anatomic orifice ...

MULTIPLE-FIRING SUTURE FIXATION DEVICE AND METHODS FOR USING AND MANUFACTURING SAME

A multiple-firing clip device includes a hollow shaft defining a lateral opening communicating with an environment and a distal shaft portion between the lateral opening and a distal end opening. A shuttle longitudinally moves on the shaft and comprises a shuttle body defining a lumen surrounding the shaft, a snare, and a snare-extender slide defining a snare track to form a snare travel path in which the snare is disposed from the body and through the track and a portion of the body. The slide moves along a given extent defining a slide distance and a distal end and movement of the slide to the distal end shortens the snare travel path to extend the snare portion through the lateral opening, through the distal shaft portion, and distally out from a distal side of the body longer than the given extent to secure a suture with the snare. 1. A multiple-firing clip device , comprising:a plurality of suture fixation clips each having an internal hollow shaped to receive therein at least one suture;a hollow shaft having a distal fixation location, an exterior surface, a distal shaft end, and an interior; the plurality of the suture fixation clips stacked in the interior, defining a first clip, and configured to move along a longitudinal axis; the shaft defining a lateral opening proximal to the distal fixation location; the lateral opening communicating between the interior and an environment outside the exterior surface;a clip movement assembly within the interior of the shaft and configured to deliver the first clip to the distal fixation location by moving the first clip longitudinally from a first proximal position into the distal fixation location; and a shuttle body comprising a hollow, snare-guiding tube having a distal tube end;', 'a snare operatively connected to the shuttle body and having a distal snare portion; and', 'a snare-extender slide defining a snare track aligned with the snare-guiding tube to form a snare travel path; the snare being disposed within a ...

METHODS AND APPARATUS FOR CONTROLLING THE INTERNAL CIRCUMFERENCE OF AN ANATOMIC ORIFICE OR LUMEN

An implantable device is provided for controlling shape and/or size of an anatomical structure or lumen. The implantable device has an adjustable member configured to adjust the dimensions of the implantable device. The implantable device is housed in a catheter and insertable from a minimally invasive surgical entry. An adjustment tool actuates the adjustable member and provide for adjustment before, during or after the anatomical structure or lumen resumes near normal to normal physiologic function. 1. An implantable prosthetic device delivery system , comprising:a housing sheath;a catheter assembly including an actuating catheter disposed within the housing sheath and a core catheter disposed within the actuating catheter, the actuating catheter including at least one longitudinally extending slot, and a retention tab having an attachment tab slideably received within the slot;a deployment umbrella including a plurality of support struts, at least one of the support struts attached to the attachment tab; andan implantable device including an adjustable member configured to adjust a dimension of the implantable device, the implantable device configured to be releasably attached to the deployment umbrella and for being received in the housing sheath.2. The system of claim 1 , wherein the core catheter is coaxially arranged within the actuating catheter forming an annular lumen therebetween.3. The system of claim 2 , wherein the retention tab is slideably received within the lumen.4. The system of claim 1 , wherein the actuating catheter includes a plurality of longitudinally extending slots claim 1 , and a corresponding number of retention tabs each having an attachment tab slideably received within a corresponding slot.5. The system of claim 1 , wherein the deployment umbrella further includes a plurality of support arms attached to the plurality of support struts and to the core catheter.6. The system of claim 5 , wherein the implantable device is configured to ...

SEALABLE ENDOVASCULAR IMPLANTS AND METHODS FOR THEIR USE

A prosthetic implant includes a circumferentially adjustable sealing collar and a rotatable sealer gear. The sealing collar has a central longitudinal axis. The rotatable sealer gear is coupled to and disposed within the sealing collar and configured to adjust the circumference of the sealing collar. The sealer gear is radially offset relative to the central longitudinal axis of the sealing collar. Rotating the sealer gear in a first direction relative to the sealing collar circumferentially expands the sealing collar. Rotating the sealer gear in a second direction relative to the sealing collar circumferentially contracts the sealing collar. 1. A prosthetic implant , comprising:a circumferentially adjustable sealing collar having a central longitudinal axis; anda rotatable sealer gear coupled to and disposed within the sealing collar and configured to adjust the circumference of the sealing collar, wherein the sealer gear is radially offset relative to the central longitudinal axis of the sealing collar,wherein rotating the sealer gear in a first direction relative to the sealing collar circumferentially expands the sealing collar, andwherein rotating the sealer gear in a second direction relative to the sealing collar circumferentially contracts the sealing collar.2. The prosthetic implant of claim 1 , wherein the sealing collar has a fixed end portion and a movable end portion claim 1 , and wherein circumferentially expanding and circumferentially contracting the sealing collar includes moving the movable end portion of the sealing collar relative to the fixed end portion of the sealing collar.3. The prosthetic implant of claim 1 , wherein the sealing collar has a plurality of slots claim 1 , and wherein the sealer gear has a plurality of teeth configured to engage the slots of the sealing collar.4. The prosthetic implant of claim 1 , further comprising a tubular implant body to which the sealing collar is coupled.5. The prosthetic implant of claim 1 , further ...

MULTIPLE-FIRING SUTURE FIXATION DEVICE AND METHODS FOR USING AND MANUFACTURING SAME

A multiple-firing clip device includes a hollow shaft defining a lateral opening communicating with an environment and a distal shaft portion between the lateral opening and a distal end opening. A shuttle longitudinally moves on the shaft and comprises a shuttle body defining a lumen surrounding the shaft, a snare, and a snare-extender slide defining a snare track to form a snare travel path in which the snare is disposed from the body and through the track and a portion of the body. The slide moves along a given extent defining a slide distance and a distal end and movement of the slide to the distal end shortens the snare travel path to extend the snare portion through the lateral opening, through the distal shaft portion, and distally out from a distal side of the body longer than the given extent to secure a suture with the snare. 1. A multiple-firing clip device , comprising:a hollow shaft having a distal clip fixation location, an exterior surface, a distal shaft end, and an interior, the shaft defining a lateral opening proximal to the distal clip fixation location, the lateral opening communicating between the interior and an environment outside the exterior surface;a plurality of suture fixation clips each having an internal hollow shaped to receive therein at least one suture, the plurality of the suture fixation clips stacked in the interior, defining a first clip, and configured to move along a longitudinal axis;a clip movement assembly within the interior of the shaft and configured to deliver the first clip to the distal clip fixation location by moving the first clip longitudinally from a first proximal position into the distal clip fixation location; and a snare-movement body comprising a hollow, snare-guiding tube having a distal tube end;', 'a snare operatively connected to the snare-movement body and having a distal snare portion; and', 'an interior body defining a portion of a snare guide path aligned with the snare-guiding tube to form a snare ...

Surgical implant devices and methods for their manufacture and use

A method of implanting a device in a heart includes inserting an implant into a blood vessel with a delivery apparatus. The implant includes a stent member and an adjustment member. The stent member is circumferentially expandable and contractible. The adjustment member is coupled to the stent member. The delivery apparatus includes a rotatable shaft and a locking mechanism coupled to an end portion of the shaft. The shaft of the delivery apparatus is releasably coupled to the adjustment member of the implant by the locking mechanism of the delivery apparatus. The method further includes positioning the implant at an implantation location within a heart by manipulating the delivery apparatus, and rotating the shaft of the delivery apparatus relative to the stent member of the implant to actuate the adjustment member of the implant. Actuating the adjustment member results in circumferential expansion or contraction of the stent member.

SEALABLE ENDOVASCULAR IMPLANTS AND METHODS FOR THEIR USE

A method of implanting a prosthetic implant includes advancing a prosthetic implant into a patient's vasculature with a delivery apparatus, the delivery apparatus comprising a catheter and a control lead, the catheter including a lumen extending therethrough, the control lead extending through the lumen of the catheter, the prosthetic implant comprising an implant body, a seal extending radially outwardly from the implant body, and a locking bar coupled to the implant body and releasably coupled to the control lead, the locking bar radially offset relative to the central longitudinal axis of the implant body. The method further includes rotating the control lead of the delivery apparatus in a first direction relative to the catheter such that the locking bar rotates in the first direction relative to the implant body and the implant body expands radially from a first radially compressed state to a first radially expanded state. 1. A method of implanting a prosthetic implant , comprising:advancing a prosthetic implant into a patient's vasculature with a delivery apparatus, the delivery apparatus comprising a catheter and a control lead, the catheter including a lumen extending therethrough, the control lead extending through the lumen of the catheter, the prosthetic implant comprising an implant body, a seal extending radially outwardly from the implant body, and a locking bar coupled to the implant body and releasably coupled to the control lead, the implant body including an inflow end portion, an outflow end portion, and a central longitudinal axis extending from the inflow end portion to the outflow end portion, the seal configured for contacting native vascular tissue and reducing leakage between the native vascular tissue and the implant body, the locking bar radially offset relative to the central longitudinal axis of the implant body; androtating the control lead of the delivery apparatus in a first direction relative to the catheter such that the locking bar ...

SEALABLE ENDOVASCULAR IMPLANTS AND METHODS FOR THEIR USE

A prosthetic implant includes a circumferentially adjustable sealing collar and a rotatable sealer gear. The sealing collar has a central longitudinal axis. The rotatable sealer gear is coupled to and disposed within the sealing collar and configured to adjust the circumference of the sealing collar. The sealer gear is radially offset relative to the central longitudinal axis of the sealing collar. Rotating the sealer gear in a first direction relative to the sealing collar circumferentially expands the sealing collar. Rotating the sealer gear in a second direction relative to the sealing collar circumferentially contracts the sealing collar. 1. A vascular system , comprising:a delivery apparatus having a catheter and a control lead, wherein the catheter includes a lumen extending therethrough, and wherein the control lead extends through the lumen of the catheter and is configured to be manipulated by a user of the vascular system; andan endovascular device releasably coupled to the delivery apparatus and having an implant body, a seal extending radially outwardly from the implant body, a housing coupled to the implant body, and a rotatable member disposed in the housing, wherein the implant body has an inflow end portion, an outflow end portion, and a central longitudinal axis extending from the inflow end portion to the outflow end portion, wherein the seal is configured to contact native vascular tissue to reduce leakage between the native vascular tissue and the implant body, wherein the rotatable member can be releasably coupled to the control lead, and wherein the rotatable member is configured to rotate relative to the housing and the implant body about an axis that is radially offset relative to the central longitudinal axis of the implant body,wherein rotating the control lead such that the rotatable member rotates in a first direction results in radial expansion of the implant body, and wherein rotating the control lead such that the rotatable member ...

SURGICAL IMPLANT DEVICES AND METHODS FOR THEIR MANUFACTURE AND USE

Sealable and repositionable implant devices are provided with one or more improvements that increase the ability of implants such as endovascular grafts to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and/or with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes an implant body and a selectively adjustable assembly attached to the implant body, having adjustable elements, and operable to cause a configuration change in a portion of the implant body and, thereby, permit implantation of the implant body within an anatomic orifice to effect a seal therein under normal physiological conditions. 1. An assembly , comprising:an implant body having a stent member and an adjustment member, wherein the stent member is circumferentially expandable and contractible, the adjustment member is coupled to the stent member, and actuating the adjustment member results in circumferential expansion or contraction of the stent member; anda delivery apparatus having a rotatable shaft and a locking mechanism coupled to an end portion of the shaft, wherein the shaft is configured to actuate the adjustment member of the implant body upon rotation of the shaft, and the locking mechanism is configured to selectively couple the shaft to the adjustment member of the implant body.2. The assembly of claim 1 , wherein the locking mechanism is movable between a first configuration and a second configuration claim 1 , wherein the locking mechanism engages the adjustment member such that axial movement of the shaft results in corresponding axial movement of the adjustment member when the locking mechanism is in the first configuration claim 1 , and wherein the locking member disengages the adjustment member such the shaft can move axially relative to the adjustment member when the locking mechanism is in the ...

ACTIVELY CONTROLLABLE STENT, STENT GRAFT, HEART VALVE AND METHOD OF CONTROLLING SAME

A prosthetic heart valve includes a frame, a valve, and an expansion element. The frame is movable between contracted and expanded configurations and includes first struts and second struts non-hingedly coupled together. The second struts are configured to pivot relative to the first struts as the frame moves between the contracted and expanded configurations. The valve is coupled to the frame and includes leaflets. The expansion element extends through a lumen of the first struts. The expansion element is slidable relative to the lumen of the first struts and is configured to move the frame incrementally from the contracted configuration and the expanded configuration and from the expanded configuration to the contracted configuration. 1. A prosthetic heart valve comprising:a stent assembly radially movable between a contracted configuration and an expanded configuration and comprising a plurality of longitudinally extending struts and a plurality of laterally extending arms, wherein the longitudinally extending struts and the laterally extending arms are formed from one integral piece of shape memory metal and are fixedly coupled together, wherein one or more of the longitudinally extending struts comprises a bore extending longitudinally therethrough, and wherein the laterally extending arms are configured to flex relative to the longitudinally extending struts as the stent assembly moves between the contracted configuration and the expanded configuration;a valve assembly coupled to the stent assembly and comprising a plurality of leaflets, wherein the leaflets are coupled together and are configured to move between an open configuration and a closed configuration, wherein in the open configuration blood can flow through the prosthetic heart valve in a first direction, and wherein in the closed configuration blood is restricted from flowing through the prosthetic heart valve in a second direction, which is opposite the first direction; andan expansion shaft ...

Actively controllable heart valve implant and method of controlling same

A method of implanting a replacement mitral valve can include expanding a replacement mitral valve to a first expanded configuration. The replacement mitral valve can include a force-expanding mitral valve lattice and a self-expanding valve trampoline lattice. The mitral valve lattice has an inflow end portion and an outflow end portion, and the valve trampoline lattice is attached to the outflow end portion of the mitral valve lattice. The method can also include rotating a plurality of jack screws connected to the mitral valve lattice. The jack screws can be configured to expand the mitral valve lattice from the first expanded configuration to a second expanded configuration.

SURGICAL IMPLANT DEVICES AND METHODS FOR THEIR MANUFACTURE AND USE

A vascular system includes a delivery apparatus and an endovascular device. The delivery apparatus including a catheter and a control lead. The control lead extends through a lumen of the catheter and is configured to be manipulated by a user. The endovascular device is releasably coupled to the delivery apparatus and includes an implant body, a seal extending radially outwardly from the implant body, and one or more tissue engaging elements. The seal is configured to contact native vascular tissue to reduce leakage between the native vascular tissue and the implant body. The tissue engaging elements are pivotable relative to the seal from a compressed state to an expanded state. In the compressed state, the tissue engaging elements are positioned so as to disengage the native vascular tissue. In the expanded state, the tissue engaging elements extend outwardly from the seal and are configured to engage the native vascular tissue. 1. A vascular system comprising:a delivery apparatus including a catheter and a control lead, wherein the catheter includes a lumen extending therethrough, and wherein the control lead extends through the lumen of the catheter and is configured to be manipulated by a user of the vascular system; andan endovascular device releasably coupled to the delivery apparatus and including an implant body, a seal extending radially outwardly from the implant body, and one or more tissue engaging elements, each having a free end and fixed end, wherein the implant body has an inflow end portion, an outflow end portion, and a central longitudinal axis extending from the inflow end portion to the outflow end portion, wherein the seal is configured to contact native vascular tissue to reduce leakage between the native vascular tissue and the implant body, wherein the tissue engaging elements are pivotable relative to the seal from a compressed state to an expanded state, wherein in the compressed state, the free ends of the tissue engaging elements are ...

Actively controllable stent, stent graft, heart valve and method of controlling same

A delivery apparatus can include a handle portion and at least one rotatable drive shaft. The handle portion can have an actuation mechanism with a motor. The rotatable drive shaft can have a proximal end portion and a distal end portion. The proximal end portion of the rotatable drive shaft can be coupled to the motor, and the distal end portion of the rotatable drive shaft can be configured to be releasably coupled to a prosthetic heart valve. The actuation mechanism can be configured to control and monitor expansion of the prosthetic heart valve and to control and monitor torque of the motor.

Actively Controllable Stent, Stent Graft, Heart Valve and Method of Controlling Same

A method for implanting a stent includes contracting a self-expanding/forcibly-expanding stent of a shape-memory material set to a given shape to a reduced implantation size with a delivery system having drive wires. The stent has a selectively adjustable assembly with adjustable elements operatively connected to the drive wires such that, when the adjustable elements are adjusted by the drive wires, a configuration change in at least a portion of the self-expanding stent occurs. The contracted stent is inserted into a native annulus in which the stent is to be implanted. The drive wires are rotated with the delivery system to forcibly expand the stent into the native annulus. While rotating the drive wires, a torque applied to the drive wires is determined with the delivery system. Rotation of the drive wires is stopped based upon a value of the determined torque. 1. A method for implanting a stent , which comprises:contracting a self-expanding/forcibly-expanding stent of a shape-memory material set to a given shape to a reduced implantation size with a delivery system having drive wires, the stent having a selectively adjustable assembly with adjustable elements operatively connected to the drive wires such that, when the adjustable elements are adjusted by the drive wires, a configuration change in at least a portion of the self-expanding stent occurs;inserting the contracted stent into a native annulus in which the stent is to be implanted;rotating the drive wires with the delivery system to forcibly expand the stent into the native annulus;while rotating the drive wires, determining with the delivery system a torque applied to the drive wires; andstopping rotation of the drive wires based upon a value of the determined torque.2. The method according to claim 1 , which further comprises providing a user with a dynamic value of the torque and permitting the user to change the expansion and contraction of the stent.3. The method according to claim 2 , which ...

SURGICAL IMPLANT DEVICES AND METHODS FOR THEIR MANUFACTURE AND USE

An implantable vascular device comprises an expandable and compressible implant body, a housing, a rotatable member, and a locking member. The housing is coupled to a first end portion of the implant body. The rotatable member is coupled to the housing and to a second end portion of the implant body such that rotating the rotatable member relative to the housing and the implant body expands or contracts the implant body. The locking member is coupled to the rotatable member and configured to move between an unlocked state and a locked state. In the unlocked state, the locking member allows the rotatable member to be rotated relative to the housing and the implant body. In the locked state, the locking member prevents the rotatable member from being rotated relative to the housing and the implant body. 1. An implantable vascular device , comprising:a tubular implant body having a sealable circumferential collar and a housing, wherein the sealable circumferential collar has a first end portion and a second end portion, and wherein the housing is coupled to the first end portion of the sealable circumferential collar;a variable sealing device having a rotatable member coupled to the housing of the tubular implant body and to the second end portion of the sealable circumferential collar, wherein the variable sealing device is configured such that rotating the rotatable member in a first direction relative to the housing and the second end portion of the sealable circumferential collar circumferentially expands the sealable circumferential collar and such that rotating the rotatable member in a second direction relative to the housing and the second end portion of the sealable circumferential collar circumferentially contracts the sealable circumferential collar; anda locking member coupled to the rotatable member of the variable sealing device, wherein the locking member is configured to move between an unlocked state and a locked state,wherein when the locking member ...

Infusion Pump System and Related Methods

An infusion pump system including an infusion tubing for delivering a fluid, a heat exchanger cartridge in fluid communication with the infusion tubing and removably coupled to at least one thermal element for heating or cooling the fluid, a motor driven pump in mechanical communication with the infusion tubing and configured to pump the fluid through the infusion tubing and the heat exchanger cartridge, and a central controller in electrical communication with the motor driven pump and the at least one thermal element. The central controller is configured to selectively deliver the fluid to a patient without heating or cooling the fluid by causing the motor driven pump to pump the fluid through the infusion tubing and the heat exchanger cartridge while the thermal element is off. 1. An infusion pump system , comprising:an infusion tubing for delivering a fluid;a heat exchanger cartridge in fluid communication with the infusion tubing and removably coupled to at least one thermal element for heating or cooling the fluid;a motor driven pump in mechanical communication with the infusion tubing and configured to pump the fluid through the infusion tubing and the heat exchanger cartridge; anda central controller in electrical communication with the motor driven pump and the at least one thermal element;wherein the central controller is configured to selectively deliver the fluid to a patient without heating or cooling the fluid by causing the motor driven pump to pump the fluid through the infusion tubing and the heat exchanger cartridge while the thermal element is off.2. The infusion pump system of claim 1 , wherein the central controller is configured to deliver the fluid without heating or cooling according to a default mode of the central controller.3. The infusion pump system of claim 2 , further comprising a user interface in electrical communication with the central controller claim 2 , wherein the user interface comprises a heating input claim 2 , and wherein ...

ACTIVELY CONTROLLABLE STENT, STENT GRAFT, HEART VALVE AND METHOD OF CONTROLLING SAME

A delivery apparatus can include a handle portion and at least one rotatable drive shaft. The handle portion has an actuation mechanism. The actuation mechanism includes a motor and one or more actuators. The rotatable drive shaft has a proximal end portion and a distal end portion. The proximal end portion is coupled to the motor, and the distal end portion is configured to be releasably coupled to a prosthetic heart valve. The actuation mechanism is configured to control and monitor expansion of the prosthetic heart valve. The handle is configured for actuating the actuation mechanism, tracking a response of native tissue when the prosthetic heart valve is in contact with the native tissue, and stopping expansion of the prosthetic heart valve once a rate of change of expansion of the prosthetic heart valve declines below a threshold. 1. A delivery apparatus , comprising:a handle portion comprising an actuation mechanism, wherein the actuation mechanism includes a motor and one or more actuators; andat least one rotatable drive shaft having a proximal end portion and a distal end portion, wherein the proximal end portion is coupled to the motor, and the distal end portion is configured to be releasably coupled to a prosthetic heart valve,wherein the actuation mechanism is configured to control and monitor expansion of the prosthetic heart valve, andwherein the handle is configured for actuating the actuation mechanism, tracking a response of native tissue when the prosthetic heart valve is in contact with the native tissue, and stopping expansion of the prosthetic heart valve once a rate of change of expansion of the prosthetic heart valve declines below a threshold.2. The delivery apparatus of claim 1 , wherein the handle is configured for expanding the prosthetic heart valve synchronized with contractions of a native heart to coincide with any particular portion of a sinus rhythm.3. The delivery apparatus of claim 1 , wherein the handle is configured for ...

METHODS AND APPARATUS FOR CONTROLLING THE INTERNAL CIRCUMFERENCE OF AN ANATOMIC ORIFICE OR LUMEN

An implantable device is provided for controlling at least one of shape and size of an anatomical structure or lumen. An implantable device has an adjustable member configured to adjust the dimensions of the implantable device. An adjustment tool is configured to actuate the adjustable member and provide for adjustment before, during and after the anatomical structure or lumen resumes near normal to normal physiologic function. 1. An adjustable prosthetic implant for controlling at least one of a shape and size of an anatomical structure or lumen , comprising:a ring shaped member having an opening;a first draw string extending within the opening and having an end extending outwardly of the opening for engagement therewith; a first plurality of wedge shaped shaping members disposed within the ring shaped member;', 'whereby tensioning of the first and second draw string by engagement of their ends causes the ring shaped member to assume a predetermined configuration., 'a second draw string extending within the opening and having an end extending outwardly of the opening for engagement therewith; and'}2. The adjustable prosthetic implant of claim 1 , wherein the shaping members adjust the ring shaped member into a three-dimensional shape.3. The adjustable prosthetic implant of claim 1 , wherein the plurality of shaping members include a right most shaping member and a left most shaping member; wherein the first draw string comprises a right draw string and the second draw string comprises a left draw string claim 1 , and wherein the right draw string is attached to the left most shaping member and the left draw string is attached to the right most shaping member.4. The adjustable prosthetic implant of claim 1 , further including a second plurality of shaping members disposed within the opening of the ring shaped member claim 1 , wherein the first plurality of shaping members is spaced apart from the second plurality of shaping members.5. The adjustable prosthetic ...

Sealable Endovascular Implants and Methods for Their Use

A sealable vascular endograft system for placement in a vascular defect includes a delivery catheter shaped to be disposed within a blood vessel. The delivery catheter includes an implant delivery catheter sheath defining an implant delivery catheter lumen and an endovascular implant removably disposed within the implant delivery catheter lumen in a compressed or folded state for delivery thereof to the vascular defect. The endovascular implant includes a tubular implant body and a sealable circumferential collar including a variable sealing device and a control lead traversing from the variable sealing device to a user and controlling variability of the variable sealing device by the user. The sealing device and the control lead cooperate to reversibly expand and contract the sealable circumferential collar to circumferentially adjust during deployment thereof to achieve a repositionable fluid-tight seal between the sealable circumferential collar and the internal walls proximal to the vascular defect. 1. A sealable vascular endograft system for placement in a vascular defect , comprising: an implant delivery catheter sheath defining an implant delivery catheter lumen; and', a tubular implant body; and', a variable sealing device; and', 'a control lead traversing from the variable sealing device to a user and controlling variability of the variable sealing device by the user, the variable sealing device and the control lead cooperating to reversibly expand and contract the sealable circumferential collar such that the sealable circumferential collar circumferentially adjusts during deployment thereof to achieve a repositionable fluid-tight seal between the sealable circumferential collar and the internal walls of the blood vessel., 'a sealable circumferential collar at the tubular implant body and including], 'an endovascular implant removably disposed within the implant delivery catheter lumen in a compressed or folded state for delivery thereof to the vascular ...

SURGICAL IMPLANT DEVICES AND METHODS FOR THEIR MANUFACTURE AND USE

This disclosure is directed toward sealable and repositionable implant devices that are provided with one or more improvements that increase the ability of implants such as endovascular grafts to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and/or with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. 1. An endograft implant system , comprising: a sheath defining a lumen;', 'an external end; and', 'an internal end; and, 'an implant delivery catheter sized to be placed within an anatomic space comprising an internal wall, the implant delivery catheter comprising a tubular implant body comprising an elastic end and an implant lumen, the elastic end comprising a sealable circumferential collar having a diameter;', 'a variable sealing device contained within the sealable circumferential collar, the variable sealing device being operable to reversibly vary the diameter of the sealable circumferential collar;', 'a control lead releasably, directly, and mechanically connected to the variable sealing device to reversibly vary the diameter of the variable sealing device when the control lead is rotated; and', 'a plurality of retractable retention tines pivotally mounted within the variable sealing device such that, when the control lead is rotated to expand the diameter of the sealable circumferential collar, the retractable retention tines are exposed outwardly from the variable sealing device to engage the internal wall adjacent the elastic end and, when the control lead is rotated to reduce the diameter of the sealable circumferential collar, the retractable retention tines withdraw inwardly into the variable sealing device., 'an endograft implant at least one of compressed and folded within the lumen at the internal end of the implant delivery catheter lumen, the endograft implant comprising2. The endograft ...

Multiple-firing suture fixation device and methods for using and manufacturing same

A multiple-firing crimp device comprises crimps, a shaft, a crimp movement assembly, and a snare. Each crimp has an internal hollow. The shaft has a distal crimping location, an exterior surface, and an interior with the clips stacked therein, the crimps moving therein along a longitudinal axis. The shaft defines a lateral opening proximal to the crimping location and communicates the interior to the environment outside the exterior surface. The crimp movement assembly within the shaft delivers the first crimp to the distal crimping location by moving the first crimp longitudinally from a first proximal position into the distal crimping location and returning to a second proximal position without the first crimp. The snare pulls at least one cord from distal of the first crimp through the first crimp and through a portion of the shaft and out the side of the shaft through the lateral opening.

MULTIPLE-FIRING SUTURE FIXATION DEVICE AND METHODS FOR USING AND MANUFACTURING SAME

A multiple-firing clip device comprises a shaft comprising an exterior surface, an interior receiving therein suture fixation clips, and a distal end opening shaped to eject a suture fixation clip therefrom. The shaft defines a lateral opening and a distal shaft portion between the lateral opening and the distal end opening. A shuttle moves on the shaft and comprises a shuttle body, a snare having a distal snare portion, and a snare extension slide movable from the shuttle body along a given extent defining a slide distance and a distal end. The shuttle extends at least the distal snare portion distally through the lateral opening from the environment into the interior, through the distal shaft portion, and through the distal end opening along a length that is at least equal to the slide distance when the snare extension slide moves to the distal end of the given extent. 1. A multiple-firing clip device , comprising:a plurality of suture fixation clips each having an internal hollow shaped to receive therein at least one suture;a hollow shaft having a distal fixation location, an exterior surface, and an interior; the plurality of the suture fixation clips stacked in the interior, defining a first clip, and configured to move along a longitudinal axis; the shaft defining a lateral opening proximal to the distal fixation location; the lateral opening communicating between the interior and an environment outside the exterior surface;a device movement carriage within the interior of the shaft and configured to deliver the first clip to the distal fixation location by moving the first clip longitudinally from a first proximal position into the distal fixation location; and a shuttle body;', 'a snare at least partly within the shuttle body, the snare having a distal snare portion; and', a snare-extender slide movably disposed with respect to the shuttle body along a given extent, the given extent defining a slide distance and a distal end; and', 'a snare extender ...

Herramienta de ajuste post-operatorio, aparato de fijación mínimamente invasivo y anillo tricúspide ajustable

Un dispositivo implantable para controlar las dimensiones de pasajes anatómicos internos corrige disfunciones fisiológicas resultantes de un lumen estructural que es o muy grande o muy pequeño. Se divulgan implantes que emplean varios medios para ajustar y mantener el tamaño de un orificio al cual se encuentran sujetas.

Rapid infusion system

A rapid infusion system for rapidly delivering blood and/or volume expanding fluid to a patient, said rapid infusion device comprising in combination: a portion which includes an adjustable drive mechanism and related control mechanism therefor, and a portion which includes components that come into contact with the fluid infused to the patient, and optionally wherein said system can be portable.

Rapid infusion system

A rapid infusion system for the intravenous delivery of fluids at standard and rapid flow rates. The system includes a pump assembly, a drive assembly to power the pump, and a fluid containment system that keeps the infused fluid out of direct contact with the pump assembly and that is preferably disposable and removable. In one embodiment the drive assembly includes a differential drive that interacts with more than one motor. In one embodiment, the pump assembly includes a roller pump and the pump chamber is a collapsible, preformed tube that is preferably attached to a pump cartridge frame. Optionally, the system includes a self-leveling drip chamber and the fluid containment system is disposable and includes a pump cartridge containing the drip chamber and the pump chamber, I.V. tubing, outlet infusion tubing, and a heater cartridge.

Heat exchange system for a pump device

A heat exchange system selectably controls the temperature of a fluid being delivered to a patient's body by a pump device. The heat exchange system includes a thermal element and a heat exchanger that is removably coupled under pressure to the thermal element. The heat exchanger includes a first half made from thermally conductive material that correspondingly mates with the thermal element, a second half made from thermally conductive material opposite the first half, and an internal heat exchange zone existing between the first half and the second half, wherein fluid flows therethrough. The thermal element of the heat exchange system may controllably and safely warm and/or cool the fluid prior to delivery.

Infusion fluid heat exchanger and cartridge

The present invention relates to a system for increasing the temperature of a fluid being infused into a patient's body while the infusion is taking place. The present invention also provides for improved monitoring of air in the infusion system such to prevent the introduction of air into the patient's body receiving the fluid infusion. The present invention also provides for a system pump which provides a variable flow rate that serves a vast amount of infusion needs and purposes. A disposable cartridge in accordance with the present invention will allow for the efficient transfer of heat energy to the fluid being infused into the patient's body. The cartridge will further ensure that deleterious amounts of air will not be introduced into the patient's body.

Surgical implant devices and methods for their manufacture and use

Sealable and repositionable implant devices are provided with one or more improvements that increase the ability of implants such as endovascular grafts to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and/or with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes an implant body and a selectively adjustable assembly attached to the implant body, having adjustable elements, and operable to cause a configuration change in a portion of the implant body and, thereby, permit implantation of the implant body within an anatomic orifice to effect a seal therein under normal physiological conditions.

Surgical implant devices and methods for their manufacture and use

This disclosure is directed toward sealable and repositionable implant devices that are provided with one or more improvements that increase the ability of implants such as endovascular grafts to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and/or with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant.

Sealable endovascular implants

Actively controllable stent, stent graft, heart valve and method of controlling same

Sealable and repositionable implant devices are provided with features that increase the ability of implants such as endovascular grafts and valves to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and/or with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes an implant body and a selectively adjustable assembly attached to the implant body, the assembly having adjustable elements and being operable to cause a configuration change in a portion of the implant body and, thereby, permit implantation of the implant body within an anatomic orifice to effect a seal therein under normal physiological conditions.

Actively controllable stent, stent graft, heart valve and method of controlling same

A method for implanting a stent includes contracting a self-expanding/forcibly-expanding stent of a shape-memory material set to a given shape to a reduced implantation size with a delivery system having drive wires. The stent has a selectively adjustable assembly with adjustable elements operatively connected to the drive wires such that, when the adjustable elements are adjusted by the drive wires, a configuration change in at least a portion of the self-expanding stent occurs. The contracted stent is inserted into a native annulus in which the stent is to be implanted. The drive wires are rotated with the delivery system to forcibly expand the stent into the native annulus. While rotating the drive wires, a torque applied to the drive wires is determined with the delivery system. Rotation of the drive wires is stopped based upon a value of the determined torque.

Actively controllable stent, stent graft and heart valve

Sealable and repositionable implant devices are provided to increase the ability of endovascular grafts and valves to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes a self-expanding stent of a shape-memory material set to a given shape. The stent has a wall with a portion having a first thickness and a second portion having a thickness greater than the first. The second portion defines a key-hole shaped longitudinal drive orifice. The implant includes a selectively adjustable assembly having adjustable elements and being operable to force a configuration change in at least a portion of the self-expanding stent. The adjustable elements have a part rotatably disposed within the longitudinal drive orifice.

Preformed mandibular splint

A preformed mandible splint and a method of aligning and stabilizing a fractured mandible with such a splint is disclosed. The splint is configured to approximate the curvature of the lower teeth or the gingiva of the lower jaw. The curvature of an eight inch diameter sphere approaches the geometric curvature of the human teeth and gum, therefore, the similarly configured splint of the present invention is usable for almost any child or adult. The splint is approximately U-shaped, follows the human dental arcade, and has rows of holes or slots along its outer and inner perimeter. The splint is placed on the teeth or gingiva and wired through the holes or slots to the mandible thus correctly aligning the mandible. Fractures can then be screwed into place according to the curvature of the splint. This eliminates the need of wiring the patient's jaw shut as is presently done in current interdigitation techniques where even minute errors in mandibular repair results in flagrant morbidities in the patient. The U-shape allows the patient's tongue to freely move. Because the splint uniformly fits the population it can be preformed. The gumline follows the same curvature as the teeth, therefore the splint may be used on those without teeth by being placed directly on the gingiva.

Implantable devices for controlling the size and shape of an anatomical structure or lumen

An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ.

Methods and apparatus for controlling the internal circumference of an anatomic orifice or lumen

An implantable device is provided for controlling at least one of shape and size of an anatomical structure or lumen. An implantable device has an adjustable member configured to adjust the dimensions of the implantable device. An adjustment tool is configured to actuate the adjustable member and provide for adjustment before, during and after the anatomical structure or lumen resumes near normal to normal physiologic function.

Air-trap

INFUSION FLUID HEAT EXCHANGER AND CARTRIDGE The present invention relates to a system for increasing the temperature of a fluid being infused into a patient's body while the infusion is taking place. The present invention also provides for improved monitoring of air in the infusion system such to prevent the introduction of air into the patient's body receiving the fluid infusion. The present invention also provides for a system pump which provides a variable flow rate that serves a vast amount of infusion needs and purposes. A disposable cartridge in accordance with the present invention will allow for the efficient transfer of heat energy to the fluid being infused into the patient's body. The cartridge will further ensure that deleterious amounts of air will not be introduced into the patient's body. Sheet 7 of 10 s0s

Rapid infusion system

A rapid infusion system for the intravenous delivery of fluids at standard and rapid flow rates. The system includes a pump assembly, a drive assembly to power the pump, and a fluid containment system that keeps the infused fluid out of direct contact with the pump assembly and that is preferably disposable and removable. In one embodiment the drive assembly includes a differential drive that interacts with more than one motor. In one embodiment, the pump assembly includes a roller pump and the pump chamber is a collapsible, preformed tube that is preferably attached to a pump cartridge frame. Optionally, the system includes a self-leveling drip chamber and the fluid containment system is disposable and includes a pump cartridge containing the drip chamber and the pump chamber, I.V. tubing, outlet infusion tubing, and a heater cartridge.

Actively controllable heart valve implant and methods of controlling same

A mitral valve implant includes a force-expanding mitral valve lattice having an interior orifice and a self-expanding valve trampoline attached at the interior orifice of the force-expanding mitral valve lattice. The mitral valve lattice is self-expandable to a first configuration and force expandable from the first configuration to a second configuration. The configurations can be circular or D-shaped. The mitral valve lattice comprises jack screws adjusting configurations of the mitral valve lattice. The valve trampoline has a cylindrical central region comprising valve leaflets. An outwardly flaring implant skirt is attached to the mitral valve lattice exterior. Wall-retaining wires are attached to the mitral valve lattice, are petal-shaped, and have a pre-set, radially outward, memory shape. The wires and skirt impart a force on a respective side of the native mitral valve when the mitral valve lattice is expanded within an annulus of the native mitral valve.

Implantable devices for controlling the size and shape of an anatomical structure or lumen

Apparatus for implanting surgical devices

Transcutaneous electrostimulator and methods for electric stimulation

TRANSCUTANEOUS ELECTROSTIMULATOR AND METHODS FOR ELECTROSTIMULATION Abstract of the Disclosure An electrostimulation device includes a computer generating an electrostimulation generator control signal and outputting a music signal, a transcutaneous electrostimulation generator, an electronic signal conduit, and an electrode coupler. The generator receives the generator control signal and the music signal, generates a nerve electrostimulation signal dependent upon the generator control signal, and outputs the nerve electrostimulation signal at the stimulation output and the music signal at an audio output. The coupler fits in an ear canal, has a speaker connected to the audio output to output the music signal into the ear canal when worn, and has electrostimulation electrodes conductively connected to the stimulation output through the electronic signal conduit to receive the nerve electrostimulation signal and positioned to contact tissue within the canal to transcutaneously apply the nerve electrostimulation signal thereto. The coupler supplies the nerve electrostimulation signal while music outputs from the speaker. - I 6

A can top and process

The present invention relates to a top for a beverage can and a stay-on-tab for opening the top of beverage can. The present invention also relates to a process of making a top for a beverage can and a process for making a stay-on-tab. 4896060 1 (GHMatters) P95174.AU

Transcutaneous electrostimulator and methods for electric stimulation

An electrostimulation device includes a computer generating an electrostimulation generator control signal and outputting a music signal, a transcutaneous electrostimulation generator, an electronic signal conduit, and an electrode coupler. The generator receives the generator control signal and the music signal, generates a nerve electrostimulation signal dependent upon the generator control signal, and outputs the nerve electrostimulation signal at the stimulation output and the music signal at an audio output. The coupler fits in an ear canal, has a speaker connected to the audio output to output the music signal into the ear canal when worn, and has electrostimulation electrodes conductively connected to the stimulation output through the electronic signal conduit to receive the nerve electrostimulation signal and positioned to contact tissue within the canal to transcutaneously apply the nerve electrostimulation signal thereto. The coupler supplies the nerve electrostimulation signal while music outputs from the speaker.

Magnetic docking system for the long term adjustment of an implantable device

Multiple-firing crimp device

A multiple-firing crimp device comprises crimps, a shaft, a crimp movement assembly, and a snare. Each crimp has an internal hollow. The shaft has a distal crimping location, an exterior surface, and an interior with the clips stacked therein, the crimps moving therein along a longitudinal axis. The shaft defines a lateral opening proximal to the crimping location and communicates the interior to the environment outside the exterior surface. The crimp movement assembly within the shaft delivers the first crimp to the distal crimping location by moving the first crimp longitudinally from a first proximal position into the distal crimping location and returning to a second proximal position without the first crimp. The snare pulls at least one cord from distal of the first crimp through the first crimp and through a portion of the shaft and out the side of the shaft through the lateral opening.

Recapturable left atrial appendage clipping device and methods for recapturing a left atrial appendage clip

A recapturable external LAA exclusion clip system includes a clip comprising first and second clip struts, at least one of the struts having a connector interface comprising a first portion of a lock, and a delivery device comprising a handle and an end effector. The handle comprises jaw and lock controls. The end effector is connected to the handle and comprises a clevis and first and second jaws. The jaws are connected to the clevis and operatively connected to the jaw control to actively articulate at least one of the jaws with respect to the other. At least one of the jaws has a connector comprising a second portion of the lock operatively connected to the lock control to removably lock with the first portion of the lock. The first and second portions of the lock have a locked state and are configured to unlock the locked state upon actuation of the lock control.

Implantable devices for controlling the size and shape of an anatomical structure or lumen

Abstract An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow anatomic fluids in situ. 1024a 1028b 1014a 1014b 1102 1102a10b Al1 A24 102b1 28 102 b 1021a 10124 04a104 102a6a0G 1026b %2ik 106ai06 FIG.348bi 1028a ~ ~ ~ ~ IG 35A 02b128 o

Post-operative adjustment tool, minimally invasive attachment apparatus, and adjustable tricuspid ring

An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ.

Implantable devices for controlling the size and shape of an anatomical structure or lumen

An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ.

Improved surgical implant devices and methods for their manufacture and use

Sealable and repositionable implant devices are provided with one or more improvements that increase the ability of implants such as endovascular grafts to be precisely deployed or re¬ deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and/or with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes an implant body and a selectively adjustable assembly attached to the implant body, having adjustable elements, and operable to cause a configuration change in a portion of the implant body and, thereby, permit implantation of the implant body within an anatomic orifice to effect a seal therein under normal physiological conditions.

Improved surgical implant devices and methods for their manufacture and use

Sealable and repositionable implant devices are provided with one or more improvements that increase the ability of implants such as endovascular grafts to be precisely deployed or re¬ deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and/or with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes an implant body and a selectively adjustable assembly attached to the implant body, having adjustable elements, and operable to cause a configuration change in a portion of the implant body and, thereby, permit implantation of the implant body within an anatomic orifice to effect a seal therein under normal physiological conditions.

Recapturable left atrial appendage clipping device and methods for recapturing a left atrial appendage clip

A recapturable external LAA exclusion clip system includes a clip comprising first and second clip struts, at least one of the struts having a connector interface comprising a first portion of a lock, and a delivery device comprising a handle and an end effector. The handle comprises jaw and lock controls. The end effector is connected to the handle and comprises a clevis and first and second jaws. The jaws are connected to the clevis and operatively connected to the jaw control to actively articulate at least one of the jaws with respect to the other. At least one of the jaws has a connector comprising a second portion of the lock operatively connected to the lock control to removably lock with the first portion of the lock. The first and second portions of the lock have a locked state and are configured to unlock the locked state upon actuation of the lock control.

Actively controllable stent, stent graft, heart valve and method of controlling same

Sealable and repositionable implant devices are provided to increase the ability of endovascular grafts and valves to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes a self-expanding stent of a shape-memory material set to a given shape. The stent has a wall with a portion having a first thickness and a second portion having a thickness greater than the first. The second portion defines a key-hole shaped longitudinal drive orifice. The implant includes a selectively adjustable assembly having adjustable elements and being operable to force a configuration change in at least a portion of the self-expanding stent. The adjustable elements have a part rotatably disposed within the longitudinal drive orifice.

Apparatus for controlling the internal circumference of an anatomic orifice or lumen

Transcutaneous electrostimulator and methods for electric stimulation

A transcutaneous electrostimulation device includes an electrostimulation generator providing at an output a nerve electrostimulation signal, an electronic signal conduit conductively connected to the output of the generator, and an electrode coupler shaped to form fit an ear canal of a human ear and having at least one electrostimulation electrode. The electrode is conductively connected to the electronic signal conduit to receive the nerve electrostimulation signal and is positioned at the electrode coupler to contact tissue within an ear canal and apply the nerve electrostimulation signal to the tissue transcutaneously. An audio source outputs audio signals. The electrode coupler has a speaker receiving the audio signals for output into the ear canal when the electrode coupler is worn. The generator sends the nerve electrostimulation signal to the electrode coupler while the audio signals are output. The generator modulates the nerve electrostimulation signal based upon the audio signals.

Multiple-firing securing device and methods for using and manufacturing same

Implantable devices for controlling the internal circumference of an anatomic orifice or lumen

An implantable device (10, 100, 800) for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implants are disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like.

Improved surgical implant devices and methods for their manufacture and use

IMPROVED SURGICAL IMPLANT DEVICES AND METHODS FOR THEIR MANUFACTURE AND USE Abstract Sealable and repositionable implant devices are provided with one or more improvements that increase the ability of implants such as endovascular grafts to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and/or with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes an implant body and a selectively adjustable assembly attached to the implant body, having adjustable elements, and operable to cause a configuration change in a portion of the implant body and, thereby, permit implantation of the implant body within an anatomic orifice to effect a seal therein under normal physiological conditions. WO 2012/092408 PCTIUS20111067695 1l140 - - - - - --- - - 1165 A A' 1175 -1010 1-l227 1227 '-20 1037FIi 1-l160

Infusion fluid heat exchanger and cartridge

The present invention relates to a system for increasing the temperature of a fluid being infused into a patient's body while the infusion is taking place. The present invention also provides for improved monitoring of air in the infusion system such to prevent the introduction of air into the patient's body receiving the fluid infusion. The present invention also provides for a system pump which provides a variable flow rate that serves a vast amount of infusion needs and purposes. A disposable cartridge in accordance with the present invention will allow for the efficient transfer of heat energy to the fluid being infused into the patient's body. The cartridge will further ensure that deleterious amounts of air will not be introduced into the patient's body.

Infusion fluid heat exchanger and cartridge

Actively controllable stent

Actively controllable sten, stent graft, heart valve and method of controlling same

A method for implanting a stent includes contracting a self-expanding/forcibly-expanding stent of a shape-memory material set to a given shape to a reduced implantation size with a delivery system having drive wires. The stent has a selectively adjustable assembly with adjustable elements operatively connected to the drive wires such that, when the adjustable elements are adjusted by the drive wires, a configuration change in at least a portion of the self-expanding stent occurs. The contracted stent is inserted into a native annulus in which the stent is to be implanted. The drive wires are rotated with the delivery system to forcibly expand the stent into the native annulus. While rotating the drive wires, a torque applied to the drive wires is determined with the delivery system. Rotation of the drive wires is stopped based upon a value of the determined torque.

Rapid infusion system

A rapid infusion system (10) for rapidly delivering blood and/or volume expanding fluid to patient, which includes a permanent portion and a removable portion, where the permanent portion includes adjustable drive means, and the removable portion includes sub-components that come into contact with blood.

Improved surgical implant devices and methods for their manufacture and use

Sealable and repositionable implant devices are provided with one or more improvements that increase the ability of implants such as endovascular grafts to be precisely deployed or re¬ deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and/or with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes an implant body and a selectively adjustable assembly attached to the implant body, having adjustable elements, and operable to cause a configuration change in a portion of the implant body and, thereby, permit implantation of the implant body within an anatomic orifice to effect a seal therein under normal physiological conditions.