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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 6. Отображено 6.
29-11-2016 дата публикации

Stabilizing composition for biological materials

Номер: US0009504750B2

Dry stabilizing compositions for bioactive materials include sugars and hydrolyzed proteins, and may be formed into tablets or other forms providing enhanced stability for the bioactive material. Compositions containing the bioactive materials may be produced by a method that includes (a) combining the bioactive material with other ingredients in an aqueous solvent to form a viscous slurry; (b) snap-freezing the slurry in liquid nitrogen to form solid frozen particles, beads, droplets or strings; (c) primary drying by water removal under vacuum of the product of step (b) while maintaining it at a temperature above its freezing temperature; and (d) secondary drying of the product of step (c) at maximum vacuum and a temperature of 20° C. or higher for a time sufficient to reduce the water activity to below 0.3 Aw.

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05-01-2017 дата публикации

STABILIZING COMPOSITION FOR BIOLOGICAL MATERIALS

Номер: US20170000892A1
Принадлежит: Advanced BioNutrition Corporation

Dry stabilizing compositions for bioactive materials include sugars and hydrolyzed proteins, and may be formed into tablets or other forms providing enhanced stability for the bioactive material. Compositions containing the bioactive materials may be produced by a method that includes (a) combining the bioactive material with other ingredients in an aqueous solvent to form a viscous slurry; (b) snap-freezing the slurry in liquid nitrogen to form solid frozen particles, beads, droplets or strings; (c) primary drying by water removal under vacuum of the product of step (b) while maintaining it at a temperature above its freezing temperature; and (d) secondary drying of the product of step (c) at maximum vacuum and a temperature of 20° C. or higher for a time sufficient to reduce the water activity to below 0.3 Aw. 1. A dry stabilizing composition , comprising a bioactive material , one or more disaccharides at 10-50% , one or more oligosaccharides at 10-80% , one or more polysaccharides at 0.1-10% , one or more hydrolyzed proteins at 0.5-40% , and one or more carboxylic acid salts , each percentage based on the total weight of the composition.2. The dry stabilizing composition of claim 1 , wherein the bioactive material comprises a cell claim 1 , a virus claim 1 , a bacterium claim 1 , a yeast claim 1 , a protein claim 1 , a hormone claim 1 , a vaccine claim 1 , a drug or a mixture thereof.3. The dry stabilizing composition of claim 2 , wherein the bacterium is a probiotic bacterium.4. The dry stabilizing composition of claim 2 , wherein the virus is an attenuated virus.5. The dry stabilizing composition of claim 1 , further comprising vitamin E.6. The dry stabilizing composition of claim 1 , wherein the one or more oligosaccharides comprise cyclodextrin.7. The dry stabilizing composition of claim 1 , wherein the one or more oligosaccharides comprise cyclodextrin and inulin.8. The dry stabilizing composition of claim 1 , wherein the one or more carboxylic acid salts ...

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07-11-2013 дата публикации

Stabilizing Composition for Biological Materials

Номер: US20130296165A1
Принадлежит:

Dry stabilizing compositions for bioactive materials include sugars and hydrolyzed proteins, and may be formed into tablets or other forms providing enhanced stability for the bioactive material. Compositions containing the bioactive materials may be produced by a method that includes (a) combining the bioactive material with other ingredients in an aqueous solvent to form a viscous slurry; (b) snap-freezing the slurry in liquid nitrogen to form solid frozen particles, beads, droplets or strings; (c) primary drying by water removal under vacuum of the product of step (b) while maintaining it at a temperature above its freezing temperature; and (d) secondary drying of the product of step (c) at maximum vacuum and a temperature of 20° C. or higher for a time sufficient to reduce the water activity to below 0.3 Aw. 1. A dry stabilizing composition for a bioactive material , comprising a carbohydrate component comprising between about 10% and 80% oligosaccharide , between about 5% and 30% disaccharide and between about 1% and 10% polysaccharide; and a protein component comprising between about 0.5% and 40% hydrolyzed animal or plant proteins; based on the total weight of the composition.2. The composition of claim 1 , wherein the hydrolyzed protein component comprises hydrolyzed casein claim 1 , hydrolyzed whey protein claim 1 , hydrolyzed pea protein claim 1 , hydrolyzed soy protein or a mixture thereof.3. The composition of claim 2 , wherein the hydrolyzed casein claim 2 , hydrolyzed whey protein claim 2 , hydrolyzed pea protein and hydrolyzed soy protein are extensively hydrolyzed proteins.4. The composition of claim 1 , wherein the polysaccharide comprises cellulose acetate phthalate (CAP) claim 1 , carboxy-methyl-cellulose claim 1 , pectin claim 1 , sodium alginate claim 1 , salts of alginic acid claim 1 , hydroxylpropyl methyl cellulose (HPMC) claim 1 , methyl cellulose claim 1 , carrageenan claim 1 , gellan gum claim 1 , guar gum claim 1 , gum acacia claim 1 , ...

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14-12-2017 дата публикации

STABILIZING COMPOSITION FOR BIOLOGICAL MATERIALS

Номер: US20170354737A1
Принадлежит: Advanced Bionutrition Corporation

Dry stabilizing compositions for bioactive materials include sugars and hydrolyzed proteins, and may be formed into tablets or other forms providing enhanced stability for the bioactive material. Compositions containing the bioactive materials may be produced by a method that includes (a) combining the bioactive material with other ingredients in an aqueous solvent to form a viscous slurry; (b) snap-freezing the slurry in liquid nitrogen to form solid frozen particles, beads, droplets or strings; (c) primary drying by water removal under vacuum of the product of step (b) while maintaining it at a temperature above its freezing temperature; and (d) secondary drying of the product of step (c) at maximum vacuum and a temperature of 20° C. or higher for a time sufficient to reduce the water activity to below 0.3 Aw. 1. A method for making a tablet , pill or pellet , comprising compressing a tableting mixture , wherein the tableting mixture comprises a dry stabilizing composition , wherein the dry stabilizing composition comprises a bioactive material , one or more disaccharides at 10-50% , one or more oligosaccharides at 10-80% , one or more polysaccharides at 0.1-10% , one or more hydrolyzed proteins at 0.5-40% , and one or more carboxylic acid salts , each percentage based on the total weight of the composition.2. The method of claim 1 , wherein the tablet mixture is compressed at a pressure up to 50 kN/cm.3. The method of claim 1 , wherein the tablet mixture is compressed at a temperature below 60° C.4. The method of claim 1 , wherein the tableting mixture further comprises a filler.5. The method of claim 4 , wherein the filler is selected from the group consisting of maltodextrin claim 4 , sodium carboxymethylcellulose claim 4 , calcium carboxy-methylcellulose claim 4 , colloidal silica dioxide claim 4 , and combinations thereof.6. The method of claim 1 , wherein the tableting mixture further comprises a flow agent.7. The method of claim 6 , wherein the flow agent ...

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28-01-2015 дата публикации

Stabilizing composition for biological materials

Номер: EP2827905A1
Принадлежит: Advanced Bionutrtion Corp

Dry stabilizing compositions for bioactive materials include sugars and hydrolyzed proteins, and may be formed into tablets or other forms providing enhanced stability for the bioactive material. Compositions containing the bioactive materials may be produced by a method that includes (a) combining the bioactive material with other ingredients in an aqueous solvent to form a viscous slurry; (b) snap-freezing the slurry in liquid nitrogen to form solid frozen particles, beads, droplets or strings; (c) primary drying by water removal under vacuum of the product of step (b) while maintaining it at a temperature above its freezing temperature; and (d) secondary drying of the product of step (c) at maximum vacuum and a temperature of 20°C or higher for a time sufficient to reduce the water activity to below 0.3 Aw.

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26-09-2013 дата публикации

Stabilizing composition for biological materials

Номер: CA2866889A1
Принадлежит: Advanced Bionutrtion Corp

Dry stabilizing compositions for bioactive materials include sugars and hydrolyzed proteins, and may be formed into tablets or other forms providing enhanced stability for the bioactive material. Compositions containing the bioactive materials may be produced by a method that includes (a) combining the bioactive material with other ingredients in an aqueous solvent to form a viscous slurry; (b) snap-freezing the slurry in liquid nitrogen to form solid frozen particles, beads, droplets or strings; (c) primary drying by water removal under vacuum of the product of step (b) while maintaining it at a temperature above its freezing temperature; and (d) secondary drying of the product of step (c) at maximum vacuum and a temperature of 20°C or higher for a time sufficient to reduce the water activity to below 0.3 Aw.

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