Thermally stable biuret and isocyanurate based surface modifying macromolecules and uses thereof

The invention relates to surface modifying macromolecules (SMMs) having high degradation temperatures and their use in the manufacture of articles made from base polymers which require high temperature processing. The surface modifier is admixed with the base polymer to impart alcohol and water repellency properties.

Thermoplastic polyurethane admixtures

The invention relates to admixtures of thermoplastic polyurethane base polymers that resist surface dulling and fluorinated additives and their use in the manufacture of articles, such as medical devices. For example, the admixtures of the invention are useful in the manufacture of blood dwelling medical devices, such as catheters.

Thermally stable biuret and isocyanurate based surface modifying macromolecules and uses thereof

The invention relates to surface modifying macromolecules (SMMs) having high degradation temperatures and their use in the manufacture of articles made from base polymers which require high temperature processing. The surface modifier is admixed with the base polymer to impart alcohol and water repellency properties.

THERMALLY STABLE BIURET AND ISOCYANURATE BASED SURFACE MODIFYING MACROMOLECULES AND USES THEREOF

The invention relates to surface modifying macromolecules (SMMs) having high degradation temperatures and their use in the manufacture of articles made from base polymers which require high temperature processing. The surface modifier is admixed with the base polymer to impart alcohol and water repellency properties. 29.-. (canceled)10. The surface modifier of claim 1 , wherein said surface active group is selected from the group consisting of radicals of the general formula CHF(CF)CHCH— and CHF(CF)(CHCHO)— claim 1 , whereinm is 0, 1, 2, or 3;χ is an integer between 1-10;r is an integer between 2-20; ands is an integer between 1-20.11. The surface modifier of claim 10 , wherein m is 0 or 1.12. (canceled)13. The surface modifier of claim 10 , wherein each surface active group is selected claim 10 , independently claim 10 , from (CF)(CF)CHCHO— claim 10 , (CF)(CF)CHCHO— claim 10 , (CF)(CF)CHCHO— claim 10 , CHF(CF)CHO— claim 10 , and (CF)(CF)CHO—.1460.-. (canceled)61. The surface modifier of claim 1 , wherein n is 0 claim 1 , A is diethylene glycol-orthophthalic anhydride polyester claim 1 , and B is formed from isophorone diisocyanate (IPDI) trimer.62. The surface modifier of claim 1 , wherein n is 0 claim 1 , A is polytetramethylene oxide claim 1 , and B is formed from hexamethylene diisocyanate (HDI) trimer.63. The surface modifier of claim 1 , wherein n is 0 claim 1 , A is polytetramethylene oxide claim 1 , and B is formed from isophorone diisocyanate (IPDI) trimer.64. The surface modifier of claim 1 , wherein n is 0 claim 1 , A is poly(diethylene glycol)adipate claim 1 , and B is formed from isophorone diisocyanate (IPDI) trimer.65. The surface modifier of claim 1 , wherein n is 0 claim 1 , A is poly(hexamethylene carbonate) claim 1 , and B is formed from isophorone diisocyanate (IPDI) trimer.66. The surface modifier of claim 1 , wherein n is 0 claim 1 , A is poly(ethyleneglycol)-block-poly(propyleneglycol))-block-poly(ethylene glycol) claim 1 , and B is formed ...

THERMALLY STABLE BIURET AND ISOCYANURATE BASED SURFACE MODIFYING MACROMOLECULES AND USES THEREOF

The invention relates to surface modifying macromolecules (SMMs) having high degradation temperatures and their use in the manufacture of articles made from base polymers which require high temperature processing. The surface modifier is admixed with the base polymer to impart alcohol and water repellency properties. 29.-. (canceled)10. The surface modifier of claim 1 , wherein said surface active group is selected from the group consisting of radicals of the general formula CHF(CF)CHCH— and CHF(CF)(CHCHO)— claim 1 , whereinm is 0, 1, 2, or 3;χ is an integer between 1-10;r is an integer between 2-20; ands is an integer between 1-20.11. The surface modifier of claim 10 , wherein m is 0.12. The surface modifier of claim 10 , wherein m is 1.13. The surface modifier of claim 10 , wherein each surface active group is selected claim 10 , independently claim 10 , from (CF)(CF)CHCHO— claim 10 , (CF)(CF)CHCHO— claim 10 , (CF)(CF)CHCHO— claim 10 , CHF(CF)CHO— claim 10 , and (CF)(CF)CHO—.14. The surface modifier of claim 1 , wherein n is 0.15. The surface modifier of claim 1 , wherein n is 1.16. The surface modifier of claim 1 , wherein said surface modifier has a theoretical molecular weight of less than 10 claim 1 ,000 Daltons.17. The surface modifier of claim 1 , wherein said surface modifier comprises from 5 to 30% (w/w) of said hard segment claim 1 , from 40 to 90% (w/w) of said soft segment claim 1 , and from 25 to 55% (w/w) of said surface active group.18. The surface modifier of claim 1 , wherein said surface modifier is formed by a process that comprises the steps ofa) combining a solution comprising a hexamethylene diisocyanate (HDI) biuret trimer with a solution comprising the surface active group; andb) combining the product of (a) with a solution comprising diol hydroxyl-terminated polydimethylsiloxanes block copolymer (C22).19. The surface modifier of claim 18 , wherein step (a) or step (b) is performed in the presence of a bismuth catalyst.20. The surface ...

THERMALLY STABLE BIURET AND ISOCYANURATE BASED SURFACE MODIFYING MACROMOLECULES AND USES THEREOF

The invention relates to surface modifying macromolecules (SMMs) having high degradation temperatures and their use in the manufacture of articles made from base polymers which require high temperature processing. The surface modifier is admixed with the base polymer to impart alcohol and water repellency properties. 29.-. (canceled)10. The surface modifier of claim 1 , wherein said surface active group is selected from the group consisting of radicals of the general formula CHF(CF)CHCH— and CHF(CF)(CHCHO)— claim 1 , whereinm is 0, 1, 2, or 3;χ is an integer between 1-10;r is an integer between 2-20; ands is an integer between 1-20.11. The surface modifier of claim 10 , wherein m is 0.12. The surface modifier of claim 10 , wherein m is 1.13. The surface modifier of claim 10 , wherein each surface active group is selected claim 10 , independently claim 10 , from (CF)(CF)CHCHO— claim 10 , (CF)(CF)CHCHO— claim 10 , (CF)(CF)CHCHO— claim 10 , CHF(CF)CHO— claim 10 , and (CF)(CF)CHO—.14. The surface modifier of claim 1 , wherein n is 0.15. The surface modifier of claim 1 , wherein n is 1.16. The surface modifier of claim 1 , wherein said surface modifier has a theoretical molecular weight of less than 10 claim 1 ,000 Daltons.17. The surface modifier of claim 1 , wherein said surface modifier comprises from 5 to 30% (w/w) of said hard segment claim 1 , from 40 to 90% (w/w) of said soft segment claim 1 , and from 25 to 55% (w/w) of said surface active group.18. The surface modifier of claim 1 , wherein said surface modifier is formed by a process that comprises the steps ofa) combining a solution comprising a hexamethylene diisocyanate (HDI) biuret trimer with a solution comprising the surface active group; andb) combining the product of (a) with a solution comprising diol hydroxyl-terminated polydimethysiloxane block copolymer C22.19. The surface modifier of claim 18 , wherein step (a) or step (b) is performed in the presence of a bismuth catalyst.20. The surface modifier ...

Thermoplastic polyurethane admixtures

The invention relates to admixtures of thermoplastic polyurethane base polymers that resist surface dulling and fluorinated additives and their use in the manufacture of articles, such as medical devices. For example, the admixtures of the invention are useful in the manufacture of blood dwelling medical devices, such as catheters.

Surfaces resistant to bacterial adhesion.

La invención presenta superficies formadas a partir de un polímero base mezclado con un aditivo de la invención. Las superficies pueden ser resistentes a la adhesión bacteriana. Las superficies de la invención se pueden aplicar a: (a) cualquier dispositivo o material médico que se implante o yuxtaponga a un tejido o fluido corporal humano o animal, in vivo o ex vivo, de forma permanente o por un período corto, y (b) cualquier artículo, material o dispositivo útil, médico o no, que debe mantener un estado de limpieza sin incrustaciones que sea seguro para la salud humana o animal durante un período de tiempo. En estas aplicaciones médicas y no médicas se sabe que pueden producirse fenómenos de ensuciamiento indeseables que podrían dañar a un paciente, usuario o consumidor del dispositivo, equipo o material comprometido procesado, transportado o almacenado en artículos, equipos o entornos propensos a la contaminación. Dichos fenómenos de ensuciamiento incluyen el desarrollo de biopelículas y el desarrollo de colonias bacterianas. Dicha incrustación puede causar irritación e hinchazón, reacciones alérgicas, reacciones tóxicas, intoxicaciones o infecciones.

Surfaces having lubricious or low friction properties

An article, comprising: a low friction surface comprising an oligofluorinated additive admixed with a base polymer; wherein a coefficient of friction of said low friction surface is reduced by at least 30% compared to a surface of the base polymer without said oligofluorinated additive. Said oligofluorinated additive may be according to Formula (I), Formula (II), Formula (III), or Formula (IV). A low friction surface can be created by applying said mixture of oligofluorinated additive and a base polymer to a surface, and a medical device having reduced coefficient of friction can be created by extruding, molding or coating a composition comprising an oligofluorinated additive and a base polymer.

Surfaces having lubricious or low friction properties

An article, comprising: a low friction surface comprising an oligofluorinated additive admixed with a base polymer; wherein a coefficient of friction of said low friction surface is reduced by at least 30% compared to a surface of the base polymer without said oligofluorinated additive. Said oligofluorinated additive may be according to Formula (I), Formula (II), Formula (III), or Formula (IV). A low friction surface can be created by applying said mixture of oligofluorinated additive and a base polymer to a surface, and a medical device having reduced coefficient of friction can be created by extruding, molding or coating a composition comprising an oligofluorinated additive and a base polymer.

Thermally stable biuret and isocyanurate based surface modifying macromolecules and uses thereof

The invention relates to surface modifying macromolecules (SMMs) having high degradation temperatures and their use in the manufacture of articles made from base polymers which require high temperature processing. The surface modifier is admixed with the base polymer to impart alcohol and water repellency properties.

Surfaces having lubricious or low friction properties

An article having a low friction surface containing an oligofluorinated additive admixed with a base polymer is disclosed.

Thermally stable biuret and isocyanurate based surface modifying macromolecules and uses thereof

The invention relates to surface modifying macromolecules (SMMs) having high degradation temperatures and their use in the manufacture of articles made from base polymers which require high temperature processing. The surface modifier is admixed with the base polymer to impart alcohol and water repellency properties.

Thermally stable biuret and isocyanurate based surface modifying macromolecules and uses thereof

Surfaces resistant to bacterial adhesion

Surfaces having lubricious or low friction properties

An article, comprising: a low friction surface comprising an oligofluorinated additive admixed with a base polymer; wherein a coefficient of friction of said low friction surface is reduced by at least 30% compared to a surface of the base polymer without said oligofluorinated additive. Said oligofluorinated additive may be according to Formula (I), Formula (II), Formula (III), or Formula (IV). A low friction surface can be created by applying said mixture of oligofluorinated additive and a base polymer to a surface, and a medical device having reduced coefficient of friction can be created by extruding, molding or coating a composition comprising an oligofluorinated additive and a base polymer.

Surfaces having lubricious or low friction properties