22-07-2021 дата публикации
Номер: US20210220353A1
The present application relates to a Favipiravir compound represented by Formula I, a geometric isomer, a pharmaceutically acceptable salt, a solvate and/or a hydrate thereof, and a pharmaceutical composition comprising the compound for treating a coronavirus infection. 2. The method according to claim 1 , wherein the coronavirus is SARS coronavirus (SARS-CoV) or SARS-CoV-2.3. The method according to claim 2 , wherein the coronavirus is SARS-CoV-2.4. The method according to claim 1 , wherein the disease caused by the coronavirus is a disease caused by a SARS-CoV-2 claim 1 , namely COVID-19.5. The method according to claim 1 , wherein the disease caused by the coronavirus is atypical pneumonia caused by a SARS coronavirus (SARS-CoV).6. The method according to claim 1 , wherein the disease caused by the coronavirus is a respiratory disease.7. The method according to claim 1 , wherein the disease caused by the coronavirus is simple infection claim 1 , pneumonia claim 1 , acute respiratory infections claim 1 , severe acute respiratory infection (SARI) claim 1 , hypoxic respiratory failure claim 1 , acute respiratory distress syndrome claim 1 , sepsis claim 1 , septic shock claim 1 , or severe acute respiratory syndrome (SARS).8. The method according to claim 7 , wherein the simple infection is fever claim 7 , cough and/or sore throat.9. The method according to claim 1 , wherein the mammal is bovine claim 1 , equine claim 1 , caprid claim 1 , suidae claim 1 , canine claim 1 , feline claim 1 , rodent or primate.10. The method according to claim 9 , wherein the mammal is human claim 9 , cat claim 9 , dog or pig.12. The method according to claim 11 , wherein the coronavirus is SARS coronavirus (SARS-CoV) or SARS-CoV-2.13. The method according to claim 12 , wherein the coronavirus is SARS-CoV-2.14. The method according to claim 11 , wherein the disease caused by the coronavirus is a disease caused by a SARS-CoV-2 claim 11 , namely COVID-19.15. The method according to claim ...
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