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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 25. Отображено 25.
01-04-2010 дата публикации

COMPOSITION CONTAINING 4-O-METHYLHONOKIOL FOR TREATING OR PREVENTING AMYLOID- RELATED DISEASES

Номер: KR2010036052A2
Принадлежит:

The present invention relates to a composition for treating or preventing amyloid-related diseases, said composition containing 4-O-methylhonokiol as an active ingredient. More particularly, the present invention relates to a pharmaceutical composition which contains as an active ingredient and which is useful in treating or preventing amyloid-related diseases such as Alzheimer’s disease, cognitive disorders, memory impairment, amyloidosis, etc. The inventors of the present invention first found that 4-O-methylhonokiol of the present invention inhibits the formation of beta-amyloid, and it is evidenced that 4-O-methylhonokiol can be used in the treatment and prevention of amyloid-related diseases. The inventors of the present invention have performed animal tests such as a water maze test, a passive avoidance test, and the like using experimental rats to find that 4-O-methylhonokiol is effective in the treatment or prevention of amyloid-related diseases such as Alzheimer’s disease, cognitive ...

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07-04-2017 дата публикации

모시근 추출물을 유효성분으로 함유하는 피부 미백용 화장료 조성물

Номер: KR0101724018B1

... 본 발명은 모시근 추출물을 유효성분으로 함유하는 피부 미백용 화장료 조성물에 관한 것이다. 본 발명에 따르면, 본 발명의 모시의 특정 부위인 뿌리(모시근) 추출물은 멜라닌 생합성 과정에 핵심적으로 작용하는 효소인 티로시나아제 활성을 효과적으로 저해하고, 멜라노마 세포의 멜라닌의 생합성을 억제함으로써 피부 미백 효과를 나타낼 수 있다.

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20-04-2016 дата публикации

METHOD FOR MANUFACTURING POROUS SPHERICAL FREEZE-DRIED MATERIAL AND COSMETIC COMPOSITION USING THEREOF

Номер: KR1020160042632A
Принадлежит:

The present invention relates to a porous spherical freeze-dried material, and to a cosmetic composition using the same and, more specifically, to a porous spherical freeze-dried material having a spherical shape unlike a parallel freeze-dried material used as cosmetics before, which increases a purchasing mentality of a user using cosmetics by having high mechanical strength against an external impact, having increased solubility to water by having large surficial area, and controlling transformation caused by moisture which is a disadvantage of a general freeze-dried material, while maintaining a small round bead shape. The present invention also relates to a cosmetic composition using the same. COPYRIGHT KIPO 2016 ...

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08-07-2016 дата публикации

COSMETIC COMPOSITION CONTAINING ISOSECOTANAPARTHOLIDE AS ACTIVE INGREDIENT FOR ALLEVIATING ATOPIC DERMATITIS

Номер: KR1020160082002A
Принадлежит:

The present invention relates to a cosmetic composition for alleviating atopic dermatitis, wherein the cosmetic composition contains isosecotanapartholide represented by chemical formula 1 as an active ingredient. According to the present invention, a cosmetic composition containing isosecotanapartholide, which is a compound derived from a natural material, does not have cytotoxicity; has excellent stability; exhibits an excellent function in inhibiting thymic stromal lymphopoietin (TSLP) cytokine which the most significant protein of abnormal signal transferring due to immunity imbalance basically causing atopic dermatitis; and shows an excellent function in expressing chemokine of MDC and TARC in HaCaT cells. Accordingly, the cosmetic composition can alleviate atopic dermatitis. COPYRIGHT KIPO 2016 ...

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20-07-2015 дата публикации

COSMETIC COMPOSITION FOR BRIGHTENING SKIN INCLUDING EXTRACT OF BOEHMERIA NIVEA (L.) GAUDICH AS ACTIVE INGREDIENT

Номер: KR1020150083576A
Принадлежит:

The present invention relates to a cosmetic composition for brightening skin including the extract of Boehmeria nivea (L.) GAUDICH as an active ingredient wherein the extract of Boehmeria nivea (L.) GAUDICH is allowed to inhibit activity of tyrosinase which is a core enzyme for synthesizing melanin while inhibiting biosynthesis of melanin from melanoma cells, thereby brightening skin. COPYRIGHT KIPO 2015 ...

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27-02-2018 дата публикации

이소세코타나파솔라이드를 유효성분으로 함유하는 아토피 피부염 개선용 화장료 조성물

Номер: KR0101831876B1

... 본 발명은 화학식 [1]로 표시되는 이소세코타나파솔라이드(Isosecotanapartholide)를 유효성분으로 함유하는 아토피 피부염 개선용 화장료 조성물에 관한 것이다. 화학식 [1] 본 발명에 따르면, 본 발명의 천연물 유래 화합물 이소세코타나파솔라이드(Isosecotanapartholide)를 함유한 화장료 조성물의 경우 세포독성이 발견되지 않아 안전성이 우수하고, 아토피 피부염의 근본적 원인이 되는 면역 불균형에 의한 비정상적 신호전달의 최상위 단백질인 TSLP(thymic stromal lymphopoietin) 사이토카인 저해능이 우수하며 HaCaT 세포에서 MDC 및 TARC의 캐모카인 발현 저해능이 우수하므로, 아토피 피부를 개선 시킬 수 있다.

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15-07-2015 дата публикации

A composition comprising the fruit extract of Platycarya strobilacea having skin whiting activity

Номер: KR0101536224B1

... 본 발명은 굴피나무 열매 추출물을 유효성분으로 함유하는 피부 미백용 조성물에 관한 것으로 보다 구체적으로는 조추출물, 극성용매 가용추출물 또는 비극성용매 가용 추출물을 유효성분으로 함유하는 피부 미백용 약학 조성물 및 화장료 조성물에 관한 것이다. 본 발명의 추출물은 멜라닌 생합성 과정에 핵심적으로 작용하는 효소인 티로시나제 활성을 효과적으로 저해하고, B16 멜라노마 세포의 멜라닌의 생합성을 억제하므로 미백용 약학조성물 및 화장료 조성물로 유용하게 이용될 수 있다.

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13-05-2016 дата публикации

COSMETIC COMPOSITION FOR AMELIORATING WRINKLES AND INHIBITING WRINKLE FORMATION, CONTAINING RAMIE ROOT EXTRACT AS ACTIVE INGREDIENT

Номер: KR1020160053173A
Принадлежит:

The present invention relates to a cosmetic composition for ameliorating wrinkles and inhibiting wrinkle formation, containing a ramie root extract as an active ingredient. According to the present invention, the extract of ramie root which is a specific portion of ramie stimulates the biosynthesis of collagen, a main component of the dermis, and inhibits the synthesis of matrix metalloproteinases (MMPs) which accelerates the breakdown of the dermis, thereby inhibiting and ameliorating wrinkles. COPYRIGHT KIPO 2016 ...

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22-11-2016 дата публикации

다공성 구형 동결건조물의 제조방법 및 이를 이용한 화장료 조성물

Номер: KR0101678474B1

... 본 발명은 다공성 구형 동결건조물 및 이를 이용한 화장료 조성물에 관한 것으로, 구체적으로는 종래 화장료로 사용되는 평형 동결건조물과는 달리 구형으로 이루어진 동결건조물로서, 외부의 충격에 강한 기계적 강도를 가지며, 표면적이 넓어 물에 대한 용해도가 증진되고, 일반적인 동결건조물의 단점인 습기에 의한 변형이 억제되는 동시에 원형의 작은 구슬 형태를 유지함으로써 화장료 사용자의 구매심리를 증진시킬 수 있는 다공성 구형 동결건조물 및 이를 이용한 화장료 조성물에 관한 것이다.

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13-05-2016 дата публикации

SKIN-WHITENING COSMETIC COMPOSITION CONTAINING RAMIE ROOT EXTRACT AS ACTIVE INGREDIENT

Номер: KR1020160053172A
Принадлежит:

The present invention relates to a skin-whitening cosmetic composition containing a ramie root extract as an active ingredient. According to the present invention, the extract of ramie root which is a specific portion of ramie can effectively inhibit activity of tyrosinase which is an enzyme playing a crucial role in the melanin biosynthetic step. In addition, the extract can inhibit the melanin biosynthesis in melanocytes, thereby exhibiting skin-whitening effects. COPYRIGHT KIPO 2016 ...

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25-01-2016 дата публикации

COMPOSITION COMPRISING FERMENTED PRODUCT OF CAMELLIA JAPONICA OIL OR EXTRACT THEREOF FOR PROMOTING HAIR GROWTH OR PREVENTING HAIR LOSS AND MANUFACTURING METHOD THEREOF

Номер: KR1020160008774A
Принадлежит:

The present invention relates to a fermented product of Camellia japonica oil or an extract thereof for promoting hair growth or preventing hair loss, which is obtained by removing a lipid-soluble fraction after adding the lipid-soluble solvent in a fermented solution obtained by fermenting Camellia japonica oil as yeast, and to a manufacturing method thereof. The composition and the method exhibit excellent effects in promoting hair growth and preventing hair loss, by increasing expression of hair growth-related genes and promoting proliferation of dermal papilla cells and fibroblasts without side effects. COPYRIGHT KIPO 2016 ...

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23-01-2018 дата публикации

매실, 매엽 및 매근의 발효 추출물을 함유하는 피부미백용 화장료 조성물

Номер: KR0101820854B1

... 본 발명은 매실, 매엽 및 매근의 발효 추출물을 함유하는 피부미백용 화장료 조성물에 관한 것으로, 더욱 구체적으로 발효 용기에 매실, 매엽 및 매근의 혼합물과 볏짚을 넣고 1차 자연 발효시켜 추출액을 제조한 후, 제조된 추출액에 유산균을 접종하여 2차 숙성 발효시켜 수득되는 매실, 매엽 및 매근의 발효 추출물을 유효성분으로 함유하는 피부미백용 화장료 조성물에 관한 것이다. 본 발명에 따르면, 본 발명에 따르면 매실 열매만을 이용한 추출물과 비교하여 매실, 매엽 및 매근 혼합물을 이용한 추출물에서 더 높은 피부미백 효과가 있음을 확인하였을 뿐만 아니라, 매실, 매엽 및 매근 혼합물의 발효 추출물이 더욱 향상된 피부미백 효과를 나타냄을 확인하였다.

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26-04-2017 дата публикации

저분자량 베타글루칸의 제조방법 및 그로부터 제조된 저분자량 베타글루칸을 함유하는 조성물

Номер: KR0101730619B1

... 본 발명은 저분자량 베타글루칸의 제조방법 및 그로부터 제조된 저분자량 베타글루칸을 함유하는 조성물에 관한 것으로, 본 발명은 베타글루칸을 함유하는 알칼리 용액에 50~200 KGy의 방사선을 조사함으로써 분자량이 2~20 KDa인 저분자량 베타글루칸을 제조할 수 있다. 본 발명에 의해 제조된 저분자량 베타글루칸은 피부 투과도가 우수하여 더욱 우수한 상처 치유 효과, 피부 노화 방지 효과, 면역 증진 효과를 발휘한다.

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15-05-2018 дата публикации

다공성 히알루론산 마스크 시트의 제조방법

Номер: KR0101858228B1

... 본 발명은 히알루론산에 친수성 고분자 또는 친수성 저분자 중 하나 이상의 친수성 소재가 혼합된 히알루론산 혼합액을 동결건조시켜 히알루론산 스펀지를 제조하는 단계: 및 상기 히알루론산 스펀지에 압력을 가하여 시트로 제조하는 단계;를 포함하는 것을 특징으로 하는 다공성 히알루론산 마스크 시트의 제조방법을 개시한다.

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26-04-2017 дата публикации

모시잎 추출물을 유효성분으로 함유하는 피부 미백용 화장료 조성물

Номер: KR0101730624B1

... 본 발명은 모시잎 추출물을 유효성분으로 함유하는 피부 미백용 화장료 조성물에 관한 것이다. 본 발명에 따르면, 본 발명의 모시잎 추출물은 멜라닌 생합성 과정에 핵심적으로 작용하는 효소인 티로시나아제 활성을 효과적으로 저해하고, 멜라노마 세포의 멜라닌의 생합성을 억제함으로써 피부 미백 효과를 나타낼 수 있다.

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20-07-2015 дата публикации

COSMETIC COMPOSITION INCLUDING EXTRACT OF BOEHMERIA NIVEA FOR INHIBITING AND REDUCING GENERATION OF WRINKLES

Номер: KR1020150083575A
Принадлежит:

The present invention relates to a cosmetic composition including an extract of Boehmeria nivea as an active ingredient for inhibiting and reducing generation of wrinkles. According to the present invention, the extract of Boehmeria nivea promotes biosynthesis of collagen, which is a main ingredient of skin dermis, reduces the synthesis amount of MMPs and CYR61 which accelerate decomposition of skin dermis, and thus can prevent and reduce skin wrinkles. COPYRIGHT KIPO 2015 ...

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16-09-2015 дата публикации

MORUS ALBA LEAF, RAMULUS MORI, MORI RADICIS CORTEX, MULBERRY AND PHELLINUS LINTEUS MIXED EXTRACT AND MANUFACTURING METHOD THEREOF

Номер: KR1020150105029A
Принадлежит:

The present invention relates to a mixed extract of Morus alba leaf, Ramulus mori, Moriradicis cortex, mulberry, and Phellinus linteus manufactured by the following steps: preparing dried Morus alba leaf, Ramulus mori, Moriradicis cortex, mulberry, and Phellinus linteus; pretreating the prepared herb medicinal ingredients with one or a mixture selected from a group consisting of an alcohol, vinegar, salt, ginger juice or honey; and filtering the dried herb medicinal ingredients after extracting with an extracting solvent, and to a manufacturing method thereof. According to the present invention the mixed herb medicinal extract manufactured by the manufacturing method has anti-aging, high skin moisturzing effect, and skin elasticity improving effect. COPYRIGHT KIPO 2015 ...

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16-04-2018 дата публикации

이소세코타나파솔라이드를 유효성분으로 함유하는 가려움증 억제 및 완화용 화장료 조성물

Номер: KR0101831883B1

... 본 발명은 하기 화학식 [1]로 표시되는 이소세코타나파솔라이드(Isosecotanapartholide)를 유효성분으로 함유하는 가려움증 억제 및 완화용 화장료 조성물에 관한 것이다. 화학식 [1] 본 발명에 따르면, 이소세코타나파솔라이드(Isosecotanapartholide)를 함유하는 가려움증 억제 및 완화용 화장료 조성물의 경우, 세포독성이 발견되지 않아 안전성이 우수하고 다양한 가려움증의 원인이 되는 사이토카인들 중 IL-31(Interleukin-31) 또는 IL-33(Interleukin-33) 억제시킴으로써 가려움증을 억제 및 완화시킬 수 있다.

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11-09-2018 дата публикации

COSMETIC COMPOSITION FOR EXFOLIATING SKIN CONTAINING SPICULE INCLUSION POWDER AS ACTIVE INGREDIENT USING ULTRA HIGH PRESSURE TREATMENT

Номер: KR101897401B1
Принадлежит: LEE, JAE SEOB

The present invention relates to a cosmetic composition in which alpha-hydroxy acid (AHA) and beta-hydroxy acid (BHA) which are kinds of fruit acid are included in a lumen of spicule (bone pieces) which is a bone structure of sponges (Spongilla) treated with ultra-high pressure. The spicule inclusion powder of the present invention improves skin exfoliating functions as AHA and BHA included in the lumen of spicule are continuously released with the lapse of time. Since the spicule inclusion powder promotes skin cell exfoliation and has massaging effects due to scrubbing, the spicule inclusion powder can be useful as a cosmetic composition for exfoliating skin with excellent exfoliating functions. COPYRIGHT KIPO 2018 ...

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01-06-2016 дата публикации

Composition with the fermentation product of camellia oil or the extract thereof for growing hair or preventing alopecia and the method for prodcution of it

Номер: KR0101626319B1
Принадлежит: 주식회사 바이오랜드

... 본 발명은 동백오일을 효모로 발효시켜 수득한 발효액에 지용성 용매를 첨가한 후, 지용성 분획을 제거함으로써 수득되는 동백오일 발효물 또는 이의 추출물을 함유하는 모발 성장 촉진 또는 탈모 방지용 조성물 및 그 제조방법에 관한 것으로, 부작용 없이 섬유아세포 및 진피유두세포의 증식을 촉진시키고, 모발 성장 관련 유전자들의 발현을 증가시킴으로써, 모발 성장 촉진 및 탈모 방지에 우수한 효과를 발휘한다.

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01-12-2016 дата публикации

COSMETIC COMPOSITION FOR INHIBITING PRURITUS AND ALLEVIATING ATOPIC DERMATITIS, CONTAINING ISOSECOTANAPARTHOLIDE AS ACTIVE INGREDIENT

Номер: WO2016190661A1
Принадлежит:

The present invention relates to a cosmetic composition for inhibiting and relieving pruritus or alleviating atopic dermatitis, containing, as an active ingredient, isosecotanapartholide represented by chemical formula [1] below. According to the present invention, the cosmetic composition containing isosecotanapartholide is very safe since cytotoxicity has not been observed, is capable of inhibiting and relieving pruritus by inhibiting interleukin-31 (IL-31) or interleukin-33 (IL-33) among cytokines causing various types of pruritus, has an excellent ability of inhibiting a thymic stromal lymphopoietin (TSLP) cytokine, which is the top-level protein in abnormal signaling caused by an immune imbalance, which is the fundamental cause of atopic dermatitis, and has an excellent ability of inhibiting the expression of MDC and TARC chemokines in HaCaT cells, and thus the cosmetic composition can alleviate atopic skin.

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01-04-2010 дата публикации

COMPOSITION CONTAINING 4-O-METHYLHONOKIOL FOR TREATING OR PREVENTING AMYLOID- RELATED DISEASES

Номер: WO2010036052A3
Принадлежит:

The present invention relates to a composition for treating or preventing amyloid-related diseases, said composition containing 4-O-methylhonokiol as an active ingredient. More particularly, the present invention relates to a pharmaceutical composition which contains as an active ingredient and which is useful in treating or preventing amyloid-related diseases such as Alzheimer's disease, cognitive disorders, memory impairment, amyloidosis, etc. The inventors of the present invention first found that 4-O-methylhonokiol of the present invention inhibits the formation of beta-amyloid, and it is evidenced that 4-O-methylhonokiol can be used in the treatment and prevention of amyloid-related diseases. The inventors of the present invention have performed animal tests such as a water maze test, a passive avoidance test, and the like using experimental rats to find that 4-O-methylhonokiol is effective in the treatment or prevention of amyloid-related diseases such as Alzheimer's disease, cognitive ...

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10-04-2018 дата публикации

COMPOSITION FOR ENHANCING SKIN BARRIER COMPRISING ULTRAHIGH PRESSURE EXTRACT OF SCOLOPENDRA SUBSPINIPES AS EFFECTIVE COMPONENT

Номер: KR101847483B1

The present invention relates to a composition for enhancing the skin barrier comprising an ultrahigh pressure extract of Scolopendra subspinipes as an effective component, wherein the ultrahigh pressure extract of Scolopendra subspinipes exhibits higher production amount of aquaporin-3 compared to a Scolopendra subspinipes extract obtained without an ultrahigh pressure treatment, and exhibits an improved moisturizing effect and excellent recovery rate of transdermal water loss (TWEL). Therefore, the composition comprising the ultrahigh pressure extract of Scolopendra subspinipes as an effective component of the present invention can be usefully used for cosmetics or health functional food for enhancing the skin barrier. COPYRIGHT KIPO 2018 ...

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07-12-2016 дата публикации

COSMETIC COMPOSITION CONTAINING ISOSECOTANAPARTHOLIDE AS ACTIVE INGREDIENT FOR INHIBITING AND ALLEVIATING PRURITUS

Номер: KR1020160139128A
Принадлежит:

The present invention relates to a cosmetic composition for inhibiting and alleviating pruritus, wherein the cosmetic composition contains isosecotanapartholide represented by chemical formula [1] as an active ingredient. According to the present invention, a cosmetic composition for inhibiting and alleviating pruritus, which contains isosecotanapartholide, does not have cytotoxicity found therein, has excellent safety, and can inhibit and alleviate pruritus by inhibiting interleukin-31 (IL-31) or interleukin-33 (IL-33) from cytokines causing various kinds of pruritus. COPYRIGHT KIPO 2016 ...

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12-04-2017 дата публикации

METHOD FOR PRODUCING LOW MOLECULAR WEIGHT BETA GLUCAN AND COMPOSITION WITH LOW MOLECULAR WEIGHT BETA GLUCAN MANUFACTURED THEREFROM

Номер: KR1020170039935A
Принадлежит:

The present invention relates to a method for producing low molecular weight beta glucan and a composition containing low molecular weight beta glucan manufactured therefrom. The low molecular weight beta glucan with the molecular weight of 2-20 KDa can be manufactured by irradiating an alkali solution containing beta glucan with radiation of 50-200 KGy. The low molecular weight beta glucan manufactured by the present invention has excellent skin penetrance, thereby showing excellent wound healing effects, skin anti-aging effects and immunity-boosting effects. COPYRIGHT KIPO 2017 (AA) Molecular weight change of beta glucan (BB) Molecular weight (CC) Comparative example (DD) Example ...

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