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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 23. Отображено 23.
02-10-2018 дата публикации

KCa2.3 채널 단백질을 이용한 혈관내피세포 기능 부전 진단용 조성물 및 이의 용도

Номер: KR0101903230B1
Автор: 서석효, 최신규, 김지애
Принадлежит: 이화여자대학교 산학협력단

... 본 발명은 KCa2.3 채널 단백질을 이용한 혈관내피세포의 기능 부전 진단용 조성물, 상기 조성물을 포함하는 혈관내피세포의 기능 부전 진단용 키트, 상기 조성물 또는 키트를 이용한 혈관내피세포의 기능 부전 진단을 위한 정보의 제공방법 및 혈관내피세포의 기능 부전 또는 개선 유도 물질의 스크리닝 방법에 관한 것이다. 본 발명의 카베올린-1, 클라트린, Rab5C, EEA1 또는 KCa2.3 채널의 발현 수준을 측정 및 비교하면, 혈관내피세포에서 기능부전을 진단할 수 있으므로, 혈관 질환을 조기진단 할 수 있다.

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Номер записи: 1
28-12-2017 дата публикации

COMPOSITION FOR DIAGNOSING CANCER USING POTASSIUM CHANNEL PROTEINS

Номер: WO2017222221A1
Автор: SUH, Suk Hyo, CHOI, Shin Kyu, KIM, Ji Aee
Принадлежит:

The present invention relates to a composition for diagnosing cancer using potassium channel proteins, a kit for diagnosing cancer containing the composition, and a method for providing information for cancer diagnosis. Using the composition or kit for diagnosing cancer provided by the present invention, the expression level of the potassium channels, KCa3.1 channel and KCa2.3 channel or regulatory factors thereof can be measured in sample-treated vascular endothelial cells of an individual or red blood cells isolated from an individual, and it is possible to diagnose the onset of cancer regardless of the type of cancer. Thus, the composition or kit may be widely used to determine progression levels (growth, metastasis, prognosis, and recurrence) of various cancers.

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Номер записи: 2
18-08-2011 дата публикации

SINGLE DOMAIN ANTIBODY AGAINST MUC1

Номер: WO2011099684A1
Автор: SEONG, Seung-Yong, CHO, Nam-Hyuk, CHOI, Shin Kyu, CHANG, Soog Hee, YUAN, Hai Ying, NA, Hye Young, MOON, Hye Jung, CHO, Sung Eun
Принадлежит:

The present invention relates to a single domain antibody (nanoscale antibody or NanoMAb) containing a mucin antigen 1 (MUC1) complementarity determining region (CDR) and a base sequence thereof, a mouse monoclonal antibody containing some or all of the base sequence or amino acid sequence, a humanized monoclonal antibody, a chimeric monoclonal antibody, a recombinant vector and a transformed host cell, and a pharmaceutical composition for the treatment of cancer or a composition for the diagnosis of cancer, containing some or all of an amino acid sequence constituting the single domain antibody or a polymer thereof. The antibody of the present invention has a specific and high affinity to the MUC1 tumor antigen, with only a variable region of a heavy chain antibody, and may be used for the diagnosis of cancerous tissues and as a therapeutic antitumor target, which binds various functional molecules to antibodies of the present invention to express MUC1.

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Номер записи: 3
29-12-2017 дата публикации

COMPOSITION FOR DIAGNOSING CANCER USING POTASSIUM CHANNEL PROTEINS

Номер: KR1020170143134A
Автор: SUH, SUK HYO, CHOI, SHIN KYU, KIM, JI AEE
Принадлежит:

The present invention relates to a composition for diagnosing cancer by using potassium channel proteins; to a kit for diagnosing cancer comprising the composition; and to an information providing method for diagnosing cancer. Specifically, the composition or kit for diagnosing cancer provided in the present invention may be used to diagnose the onset of cancer regardless of its type, by measuring the expression levels of potassium channels, KCa3.1 channel and KCa2.3 channel, or a regulator thereof from vascular endothelial cells treated with a sample of a subject, or from red blood cells isolated from the subject, and thus can be widely utilized in determining the stages of progression (growth, metastasis, prognosis, and recurrence) of various cancers. COPYRIGHT KIPO 2018 ...

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Номер записи: 4
29-01-2019 дата публикации

카드 조립체

Номер: KR0101918391B1
Автор: 최신규
Принадлежит: 최신규

... 본 발명은 카드 조립체에 관한 것으로서 특히, 카드의 내마모성이 우수하고, 여러 장의 카드를 결합하여 블럭놀이도 가능하도록 구성된 변신 완구용 변신 카드에 관한 것이다.

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Номер записи: 5
03-09-2018 дата публикации

CARD ASSEMBLY

Номер: KR1020180098081A
Автор: CHOI, SHIN KYU
Принадлежит:

The present invention relates to a card assembly, and more specifically, relates to a transformation card for a transformation toy which is excellent in abrasion resistance of a card and is capable of combining multiple cards to allow block play. The present invention has been made to solve a problem which the card is not used for a long time because the card is worn or wrinkled in a process of using the card formed of a paper material as described above. To achieve the above object, the card assembly according to the present invention comprises: a card unit (110); a shield (120); and a fastening means. COPYRIGHT KIPO 2018 ...

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Номер записи: 6
29-08-2013 дата публикации

TOY TOP

Номер: WO2013125834A1
Автор: CHOI, Shin-Kyu
Принадлежит:

A top which can facilitate the coupling of a winder is provided. The toy top (200) comprises: a blade (210); a shaft (223) of which one end is fixed to a lower portion of the blade; a pinion (222) to be inserted and coupled to the middle of the shaft; and a shaft holder (220) capable of accommodating the pinion-coupled shaft in a rotatable manner, wherein the shaft holder comprises winder connectors (224a, 224b) for rotating the pinion. Particularly, the winder connectors (224a, 224b) comprise: a cut portion (33) for contacting a part of a first portion (115) of a winder (116) on a lateral side; and a guide groove (34) for allowing a second portion (215) extended from the first portion (115) of the winder to be stopped at protrusions (33a, 33b) inside the cut portion so as to prevent the second portion from being separated from the lateral side when a part of the first portion of the winder is contacted to a lateral side and then the winder is moved to the lateral side.

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Номер записи: 7
29-12-2010 дата публикации

TOY SPINNING TOP

Номер: WO2010151017A3
Автор: CHOE, Sin Kyu
Принадлежит:

The present invention relates to a toy spinning top which comprises: a rotatable blade; a driving force generating part, which is engaged with the blade, for generating a driving force to rotate the blade; and an attack ring which is detachably engaged with the blade and idly rotates against the blade. Accordingly, no fragments are generated when a collision occurs between the toy spinning top and a neighboring toy spinning top or another object, and it is not dangerous even if the toy spinning top collides with the human body. Therefore, the toy spinning top can be used for safe play.

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Номер записи: 8
11-02-2016 дата публикации

MULTISTAGE SAND BARRIER FACILITY INCLUDING ECOLOGICAL PATH AND MONITORING SYSTEM

Номер: KR1020160014421A
Автор: KWON, TAE HYUK, HONG, EUN SOO, CHOI, SHIN GYU
Принадлежит:

The present invention provides an ecological path type multistage sand barrier facility, capable of minimizing damage to the surrounding landscapes and forest caused when an erosion control facility is constructed by reducing an amount of bed excavation and the amount of used concrete; and a system capable of monitoring and controlling a state of a sand barrier wall. According to an embodiment of the present invention, the ecological path type multistage sand barrier facility to prevent damage due to avalanches is arranged on different positions to change a speed and a moving direction based on a flow direction in an avalanche generated expected area. The ecological path type multistage sand barrier facility comprises: a plurality of sand barrier walls, and the sand barrier walls arranged in a zigzag in a transverse direction of the avalanche generated expected area. COPYRIGHT KIPO 2016 (A1,A2) First collision (B1,B2) Second collision ...

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Номер записи: 9
04-06-2018 дата публикации

FLEXIBLE BARRIER FOR PREVENTING DEBRIS FLOW AND METHOD FOR PREVENTING DEBRIS FLOW

Номер: KR1020180059077A
Автор: KWON, TAE HYUK, CHOI, SHIN KYU
Принадлежит:

A flexible barrier for preventing a debris flow comprises: a plurality of first wire ropes extended in a first direction, respectively, and arranged along a second direction crossing with the first direction; a plurality of second wire ropes extended in the second direction, respectively, arranged along the first direction, and connected to the first wire ropes, respectively; and a mesh supported by the first and second wire ropes and absorbing kinetic energy of the debris flow. Each of the second wire ropes and the mesh are overlapped along a third direction crossing with the first and the second directions. COPYRIGHT KIPO 2018 ...

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Номер записи: 10
24-01-2019 дата публикации

토석류 방재를 위한 유연성 방호책 및 토석류 방재 방법

Номер: KR0101942012B1
Автор: 권태혁, 최신규
Принадлежит: 한국과학기술원

... 토석류 방재를 위한 유연성 방호책은 제1 방향으로 각각 연장되고 제1 방향과 교차하는 제2 방향을 따라 배열되는 복수의 제1 와이어 로프들, 제2 방향으로 각각 연장되고 제1 방향을 따라 배열되며 제1 와이어 로프들과 각각 연결되는 복수의 제2 와이어 로프들, 및 제1 및 제2 와이어 로프들에 의해 지지되며 토석류의 운동에너지를 흡수하기 위한 그물망을 포함한다. 각각의 제2 와이어 로프들 및 그물망은 제1 및 제2 방향들과 교차하는 제3 방향을 따라 중첩된다.

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Номер записи: 11
18-05-2016 дата публикации

LAYERED DEBRIS BARRIER WITH ECO-CORRIDORS AND MONITORING SYSTEM

Номер: KR0101622337B1
Автор: 권태혁, 홍은수, 최신규
Принадлежит: 한국과학기술원

... 본 발명의 실시예에 따른 토석류에 의한 재해 방지를 위한 생태통로형 다단계 토사 차단벽 시설물은 토석류를 가두거나 속도 및 이동 방향을 변화시키도록 토석류 발생 예상 유역의 흐름 방향을 기준으로 서로 다른 위치에 배치되고, 다각형 또는 곡선의 벽체 형상을 가지는 복수개의 토사 차단벽을 포함하고, 상기 복수개의 토사 차단벽은, 상기 토석류 발생 예상 유역의 횡방향으로 지그재그 형태로 배치된다.

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Номер записи: 12
29-08-2013 дата публикации

TRANSFORMABLE TOY CAR AND PLAYING DEVICE USING SAME

Номер: WO2013125836A3
Автор: CHOE, Sin-Kyu
Принадлежит:

The present invention relates to a transformable toy car and a playing device using the same, wherein power is provided to enable the toy car to be driven and the shape of the vehicle toy is automatically transformed to show a random card by turning the card over if the card is attached while the vehicle toy is being driven.

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Номер записи: 13
29-08-2013 дата публикации

TRANSFORMABLE TOY CAR AND PLAYING DEVICE USING SAME

Номер: WO2013125836A2
Автор: CHOE, Sin-Kyu
Принадлежит:

The present invention relates to a transformable toy car and a playing device using the same, wherein power is provided to enable the toy car to be driven and the shape of the vehicle toy is automatically transformed to show a random card by turning the card over if the card is attached while the vehicle toy is being driven.

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Номер записи: 14
14-11-2013 дата публикации

TOP

Номер: WO2013168961A1
Автор: CHOI, Sin-Kyu
Принадлежит:

The present invention relates to a top generating a clear collision sound when the top collides with another top so as to make playing with a top more exciting, and having an improved fastening structure for a metal wheel on the top so as to allow the metal wheel to fully vibrate when the top collides.

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Номер записи: 15
01-04-2016 дата публикации

Composition for preventing or treating fabry disease comprising clathrin inhibitor

Номер: KR0101608141B1
Автор: 최신규, 서석효
Принадлежит: 이화여자대학교 산학협력단

... 본 발명은 파브리 질환의 예방 또는 치료용 약학적 조성물에 관한 것이다. 보다 구체적으로 본 발명은 클라스린 발현을 저해하는 물질을 포함하는 파브리 질환의 예방 또는 치료용 약학적 조성물, 상기 클라스린 발현 저해 물질을 포함하는 파브리 질환의 예방 또는 개선용 의약외품 조성물, 건강 기능 식품 조성물, 사료 또는 사료 첨가제, 음용수 또는 음용수 첨가제, 및 상기 조성물을 이용하여 파브리 질환을 예방 또는 치료하는 방법에 관한 것이다. 또한 본 발명은 클라스린 발현 수준을 측정하는 제제를 포함하는 파브리 질환 진단용 조성물 및 파브리 질환 진단을 위하여 클라스린 발현 수준을 측정하고 검출하는 방법에 관한 것이다. 본 발명에 따른 클라스린은 파브리 질환 발병시 그 발현이 비정상적으로 증가되는 것으로, 상기 클라스린을 이용하여 파브리 질환 발병 여부를 진단할 수 있을 뿐만 아니라 파브리 질환을 예방하고 치료할 수 있다. 따라서, 본 발명의 클라스린 발현 저해 물질을 유효 성분으로 포함하는 조성물은 이를 개체에 투여시 클라스린의 발현을 억제하여 파브리 질환을 효과적으로 예방, 개선 또는 치료할 수 있으며, 본 발명의 또 다른 일 양태에 따른 클라스린의 발현 수준을 측정하는 제제를 포함하는 조성물은 파브리 질환의 발병 여부 또는 발병 가능성을 효과적으로 진단할 수 있다.

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Номер записи: 16
29-12-2017 дата публикации

COMPOSITION FOR DIAGNOSING DYSFUNCTIONS OF VASCULAR ENDOTHELIAL CELLS BY USING KCa2.3 CHANNEL PROTEIN, AND USE OF SAME

Номер: KR1020170143135A
Автор: SUH, SUK HYO, CHOI, SHIN KYU, KIM, JI AEE
Принадлежит:

The present invention relates to a composition for diagnosing dysfunctions of vascular endothelial cells, which uses a KCa2.3 channel protein; a kit for diagnosing dysfunctions of vascular endothelial cells, which comprises the composition; an information providing method for diagnosing dysfunctions of vascular endothelial cells, which uses the composition or kit; and a screening method for a material which induces dysfunctions of vascular endothelial cells or improves functions of vascular endothelial cells. By measuring and comparing expression levels of caveolin-1, clathrin, Rab5C, EEA1, and KCa2.3 channel according to the present invention, dysfunctions of vascular endothelial cells can be diagnosed, thus enabling early diagnosis of vascular diseases. COPYRIGHT KIPO 2018 ...

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Номер записи: 17
29-12-2010 дата публикации

TOY SPINNING TOP

Номер: KR2010151017A2
Автор: CHOE, Sin Kyu
Принадлежит:

The present invention relates to a toy spinning top which comprises: a rotatable blade; a driving force generating part, which is engaged with the blade, for generating a driving force to rotate the blade; and an attack ring which is detachably engaged with the blade and idly rotates against the blade. Accordingly, no fragments are generated when a collision occurs between the toy spinning top and a neighboring toy spinning top or another object, and it is not dangerous even if the toy spinning top collides with the human body. Therefore, the toy spinning top can be used for safe play.

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Номер записи: 18
09-09-2015 дата публикации

COMPOSITION FOR PREVENTING OR TREATING FABRY DISEASE COMPRISING RAB5 INHIBITOR

Номер: KR0101552021B1
Автор: 최신규, 서석효, 김지애
Принадлежит: 이화여자대학교 산학협력단

... 본 발명은 파브리 질환의 예방 또는 치료용 약학적 조성물에 관한 것이다. 보다 구체적으로 본 발명은 Rab5 발현을 저해하는 물질을 포함하는 파브리 질환의 예방 또는 치료용 약학적 조성물, 상기 Rab5 발현 저해 물질을 포함하는 파브리 질환의 예방 또는 개선용 의약외품 조성물, 건강 기능 식품 조성물, 사료 또는 사료 첨가제, 음용수 또는 음용수 첨가제, 및 상기 조성물을 이용하여 파브리 질환을 예방 또는 치료하는 방법에 관한 것이다. 또한 본 발명은 Rab5 발현 수준을 측정하는 제제를 포함하는 파브리 질환 진단용 조성물 및 파브리 질환 진단을 위하여 Rab5 발현 수준을 측정하고 검출하는 방법에 관한 것이다.

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Номер записи: 19
13-04-2017 дата публикации

COMPOSITION FOR VASCULAR ENDOTHELIAL CELL DYSFUNCTION DIAGNOSIS, AND USE THEREOF

Номер: WO2017061809A1
Автор: SUH, Suk Hyo, CHOI, Shin Kyu, KIM, Ji Aee
Принадлежит:

The present invention relates to a composition, kit, and method for vascular endothelial cell dysfunction diagnosis and a method for screening a substance which induces the dysfunction or improved function of vascular endothelial cells. The method provided according to the present invention allows, when used, for the diagnosis of vascular endothelial cell dysfunction by using the expression levels of marker proteins, such as Rab5C, clathrin, caveolin-1, and early endosome antigen 1 (EEA1), and thus can be widely used for early diagnosis of various vascular diseases triggered by vascular endothelial cell dysfunction.

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Номер записи: 20
01-06-2015 дата публикации

COMPOSITION FOR PREVENTING OR TREATING FABRY DISEASE INCLUDING SUBSTANCES FOR INHIBITING EXPRESSION OF RAB5 AS ACTIVE INGREDIENT

Номер: KR1020150059550A
Автор: CHOI, SHIN KYU, SUH, SUK HYO, KIM, JI AEE
Принадлежит:

The present invention relates to a composition for preventing or treating Fabry disease. More specifically, the present invention relates to a pharmaceutical composition for preventing or treating Fabry disease including substances for inhibiting the expression of Rab5, to a quasi-drug composition, a functional health food composition, a feed or feed additive, and drinking water or a drinking water additive for preventing or treating Fabry disease including the substances for inhibiting the expression of Rab5, and to a method for preventing or treating Fabry disease by using the composition. Also, the present invention relates to a composition for diagnosing Fabry diseases including a formulation to measure the expression level of Rab5, and a method for measuring and detecting the expression level of the Rab5 to diagnose Fabry diseases. COPYRIGHT KIPO 2015 ...

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Номер записи: 21
18-04-2017 дата публикации

COMPOSITION FOR DIAGNOSING VASCULAR ENDOTHELIAL CELL DYSFUNCTION, AND USE THEREOF

Номер: KR1020170041960A
Автор: SUH, SUK HYO, CHOI, SHIN KYU, KIM, JI AEE
Принадлежит:

The present invention relates to a composition and a kit for diagnosing vascular endothelial cell dysfunction, a method for providing information to diagnose vascular endothelial cell dysfunction, and a method for screening an induction substance for improving functions of vascular endothelial cells. When estimating and comparing the expression levels of Rab5C, clathrin, caveolin-1, early endosome antigen 1 (EEA1), and KCa3.1 channel, of the present invention, it is possible to diagnose dysfunction in the vascular endothelial cells, thereby being capable of early diagnosis of vascular diseases. COPYRIGHT KIPO 2017 ...

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Номер записи: 22
09-10-2014 дата публикации

TRANSFORMABLE TOY CAR

Номер: WO2014163387A1
Автор: CHOI, Shin-Kyu
Принадлежит:

The purpose of the present invention is to provide a transformable toy car, the driving of which can be controlled from a remote location and which transforms from a car shape into an arbitrary second shape, thereby exposing the lower surface of an attached card when an arbitrary card is attached to the car while the car is traveling.

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Номер записи: 23