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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 57. Отображено 57.
24-02-2023 дата публикации

프로바이오틱스의 장기 배양공법

Номер: KR102503641B1
Принадлежит: 주식회사 에치와이

... 본 발명은 프로바이오틱스의 장기 배양공법에 관한 것으로, 상기 프로바이오틱스 장기 배양 방법 (Long-Term Fermentation)은 종래 프로바이오틱스 배양 기간에 비하여, 프로바이오틱스를 장기간 배양함으로써 프로바이오틱스의 장 세포 부착 능력을 증가 시키고, 장벽강화 기능을 나타내는 밀착연접단백질의 증가, 구체적으로는 ZO-1, 오클루딘 (Occludin, OCLN), CLDN1 및 CLDN3 중 어느 하나 이상의 발현을 증가시킬 수 있으며, 산성 환경에 노출시켜 산과 담즙에 대한 적응성이 증가, 구체적으로 구강, 위산, 소/대장에서의 생존율을 증가시킬 수 있다.

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21-11-2016 дата публикации

GENETIC MARKER FOR IDENTIFICATION AND DETECTION OF LACTOCOCCUS GARVIEAE, WHICH IS BACTERIAL PATHOGEN CAUSING STREPTOCOCCAL INFECTION, AND METHOD FOR IDENTIFICATION AND DETECTION OF BACTERIAL PATHOGEN USING SAME

Номер: KR101677952B1

The present invention relates to a genetic marker for the identification and detection of a bacterial pathogen causing streptococcal infection of fishes, and a method for the identification and detection of the bacterial pathogen using the same, and more specifically, to a method for identifying a bacterial species or detecting whether a fish is infected with the same bacterial species or not based on the melting temperature by: selecting a genetic marker containing the bacterium-specific single nucleotide polymorphism (SNP) of DNA sequences encoding 16S rDNA of Lactococcus garvieae, which is a bacterial pathogen causing streptococcal infection of fishes, and amplifying the same; hybridizing peptide nucleic acid (PNA) specifically recognizing the amplified product; obtaining a melting profile by temperature through the temperature control of the hybridized product; and analyzing the obtained melting profile. The present invention is effective in identifying a bacterial pathogen causing ...

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08-09-2022 дата публикации

혼합 프로바이오틱스 발효물을 포함하는 피부 마이크로바이옴 개선용 조성물 및 이를 포함하는 화장료 조성물

Номер: KR102441226B1
Принадлежит: 주식회사 에치와이

... 본 발명은 혼합 프로바이오틱스 발효물을 포함하는 피부 마이크로바이옴 개선용 조성물 및 이를 포함하는 화장료 조성물에 관한 것으로, 프로피오니박테리움 아크네스 (Propionibacterium acnes, P. acnes) 및 스타필로코커스 아우레우스 (Staphylococcus aureus, S. aureus) 항균능을 통한 피부 마이크로바이옴 개선능, 독성지표인 LDH (Lactate dehydrogenase), 염증지표인 IL-8의 발현을 저감능 및 보습지표인 히알루로난 (hyaluronan) 함유량 개선능이 있고, 이를 통해 피부염증 질환 개선 및 보습 효과를 제공할 수 있다.

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27-08-2020 дата публикации

LIPOSOME FOR ORALLY ADMINISTERED VACCINE FOR FISH AND METHOD FOR PRODUCING SAME

Номер: WO2020171279A1
Принадлежит:

The present invention relates to a liposome for an orally administered vaccine for fish and a method for producing same and, more specifically, to an orally administered vaccine composition for fish, comprising a liposome and streptococcal cells of fish, wherein the liposome is composed of lecithin and cholesterol and coated with chitosan. The vaccine composition for oral administration for fish comprising a liposome and streptococcal cells of fish according to the present invention is easy to inoculate and has excellent stability when administered orally, wherein the liposome is composed of lecithin and cholesterol and coated with chitosan. Therefore, the vaccine composition can effectively prevent streptococcal infections in aquaculture fish.

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16-05-2018 дата публикации

FREE-FOLDABLE BLOWER APPARATUS FOR VEHICLE VENTILATION SEAT AND VEHICLE VENTILATION SEAT INCLUDING SAME

Номер: KR101854398B1
Принадлежит: AKH WIN CO., LTD., JUNG, SEUNG HEE

A free-foldable blower apparatus for a vehicle ventilation seat according to the present invention includes a blowing motor connected to a vehicle ventilation seat; and a connecting device coupled to the blowing motor for directly collecting the air discharged from an air conditioning duct of a vehicle and supplying the collected air to a suction port of the blowing motor, wherein the connecting device includes a rib fixing hub coupled to a suction port frame of the blowing motor; a plurality of ribs, one ends of which are fixed to the rib fixing hub and which are arranged to protrude in front of the rib fixing hub in a longitudinal direction of the rib fixing while being spaced apart along the circumference of the rib fixing hub; and a windshield which is joined to the ribs and is made of a material capable of being elastically deformed to close a space between the ribs, the ribs are arranged in a tapered form with a greater distance from the center line of the fixing hub as the ribs are ...

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22-11-2022 дата публикации

허혈성 뇌졸중 또는 일과성 허혈 발작을 갖는 대상체에서의 혈압 조절을 위한 약학적 조성물

Номер: KR20220154987A
Принадлежит:

... 본 발명의 약학적 조성물은 급성기 이후 허혈성 뇌졸중 또는 일과성 허혈 발작을 갖는 대상체에 투여되어, 효과적으로 혈압을 조절할 수 있다.

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28-05-2018 дата публикации

FLEXIBLE DISPLAY DEVICE HAVING INTEGRATED SENSOR AND MANUFACTURING METHOD THEREOF

Номер: KR1020180055941A
Принадлежит:

Provided is a thinner and robust flexible display device which comprises: a substrate having first and second surfaces; display elements formed on the first surface of the substrate to display an image; a first sensor formed on the second surface of the substrate to sense a first input; and a second sensor formed on the first sensor to sense a second input. The second sensor has a layer integrated with the first sensor. COPYRIGHT KIPO 2018 ...

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17-10-2016 дата публикации

DISPLAY DEVICE

Номер: KR1020160119914A
Автор: JEONG, SEUNG HEUI
Принадлежит:

The present invention relates to a curved display device. The curved display device comprises: a display panel which has a first bending part, a second bending part, a window arranged on a surface of the display panel, and a circuit board connected to the display panel. The display panel includes a divided front display part and a lateral display part based on the first bending part. The display panel includes a pad part connected to the circuit board in the second bending part; thereby a width of a bezel being able to be reduced. COPYRIGHT KIPO 2016 ...

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02-08-2016 дата публикации

PAYMENT METHOD FOR MOBILE SERVICE SUBSCRIBER USING USIM INTERWORKING CREDIT CARD AND THE USIM INTERWORKING CREDIT CARD USED FOR SAME

Номер: KR1020160090930A
Автор: JUNG, SEUNG HEE
Принадлежит:

The present invention relates to a payment method for a mobile service subscriber using an USIM interworking credit card and the USIM interworking credit card wherein an USIM card for a smartphone used for the same. The present invention provides the payment method for the mobile service subscriber using the USIM interworking credit card including: a step of providing the USIM interworking credit card for the mobile service subscriber; a step of paying with the USIM interworking credit card; a step of transmitting payment information to a mobile-service company; a step of determining an approval of the mobile-service company on the payment; a step of transmitting approval information; and a step of billing the mobile service subscriber for the payment using the USIM interworking credit card. Thus, an effect of providing user convenience by enabling the payment with the USIM interworking credit card within a preset limit simultaneously with signing up with the mobile-service company to use ...

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19-10-2016 дата публикации

COMPOSITION FOR ENHANCING RADIATION SENSITIVITY COMPRISING miR-770-5P AS ACTIVE INGREDIENT

Номер: KR101668105B1

The present invention relates to a composition for enhancing radiation sensitivity, comprising miR-770-5p as an active ingredient. The miR-770-5p according to the present invention has an excellent effect of enhancing radiation sensitivity and an excellent chemotherapeutic assistant effect such as viability reduction of cancer cells and apoptosis induction of cancer cell in the process of radiation, thereby being able to be helpfully used as a radiation sensitivity enhancer and an adjuvant for chemotherapy. COPYRIGHT KIPO 2016 (A1,A2) Relative cell number (BB) Colony formation degree (%) ...

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08-03-2023 дата публикации

건강검진 및 보험정보 분석 기반의 건강 위험 지수 산출 방법 및 시스템

Номер: KR20230033238A
Принадлежит:

... 본 발명은, 몸무게 키등의 사용자 기본정보와, 건강검진 데이터 서버(공공기관 서버)로부터 수신된 사용자의 건강검진 정보와, 보험사로부터 수신된 사용자의 보험정보를 이용하여, 사용자의 건강 위험 지수를 검출하는, 건강검진 및 보험정보 분석 기반의 건강 위험 지수 산출 방법 및 시스템에 관한 것이다. 본 발명의 건강검진 및 보험정보 분석 기반의 건강 위험 지수 산출 시스템의 구동방법은, 메인서버가, 건강검진 데이터 서버로부터의 건강검진 데이터를 이용하여, 고혈압, 당뇨, 고지혈증의 각질환이, '정상', '위험군', '질환발병' 중 어느 하나에 속하는지를 판단하되, 고혈압일 경우에, 상기 건강검진 데이터로서 수축기 혈압과 이완기 혈압이, 기설정된 수축기 혈압과 이완기 혈압의 정상 기준치, 위험군 기준치, 질환발병 기준치와 비교하여 판단하는, 만성질환의 정도에 따른 분류단계; 만성질환의 정도에 따른 분류단계후, 메인서버는, 고혈압, 당뇨, 고지혈증의 각 질환에 따른 건강검진 데이터의 임상수치를, 건강검진 데이터별로 기 설정된 각 등급의 기준범위들에 따라 4개의 등급중 하나로 설정하고, 각 등급에 따라 기 설정된 점수를 부여하는, 만성질환별 상대 위험도 산출단계; 메인서버는, 처방된 약물의 양에서 사용자 단말기로부터 수신된 복용한 약물의 양을 분율로 나타낸 복약순응도를, 기 설정된 각 등급의 기준범위들에 따라 3개의 등급으로 나누고, 각 등급에 따라 기 설정된 점수를 부여하는, 제1 복약순응도의 점수 산출단계; 메인서버는, 만성질환의 정도에 따른 분류단계 후, 만성질환별 상대 위험도 산출단계에서 구한 건강검진 데이터의 점수들과, 제1 복약순응도의 점수 산출단계에서 구한 복약순응도의 점수를 이용하여, 각 질환별 위험지수를 검출하고, 각 질환별 위험지수를 합산하여 종합 상대 위험도를 산출하는, 종합 상대 위험도 산출단계; 메인서버는, 종합 상대 위험도 산출단계에서 검출된 종합 상대 위험도를, 7개의 등급의 기준범위들과 비교하여, 등급을 결정하고, 결정된 등급을, 보험정보 고려하지 ...

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22-08-2016 дата публикации

COMPOSITION FOR EXTERMINATING SCUTICA IN FISH CONTAINING MEBENDAZOLE

Номер: KR101650043B1

The present invention relates to a composition for exterminating Scutica in fish, comprising mebendazole as an active ingredient, and to a method for exterminating Scutica by performing the oral administration or the medicinal bath of mebendazole in fish. According to the present invention, the composition and the extermination method have excellent effects in exterminating Scutica in fish, and can be efficiently used in the aquaculture industry by performing the oral administration or the medicinal bath administration. COPYRIGHT KIPO 2016 ...

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31-08-2016 дата публикации

MOBILE TERMINAL FOR CONTROLLING HANDWRITING-RELEVANT FUNCTION THROUGH GESTURE OF HAND HAVING WRIST-WEARABLE DEVICE PUT THEREON AND METHOD FOR CONTROLLING SAME

Номер: KR1020160102811A
Принадлежит:

The present specification discloses a mobile terminal for controlling a handwriting-relevant function through the gesture of a hand having a wrist-wearable device put thereon and a method for controlling the same. According to the present specification, the mobile terminal includes: a wireless communication unit for receiving a signal transmitted from a wrist-wearable device having a wrist sensing part, which is worn on a wrist of a first hand of both hands of a user to sense a gesture of the first hand (first hand gesture), and a wireless transmission part which transmits the first hand gesture sensed by the wrist sensing part as the signal; a display unit for displaying a screen; a sensing unit for receiving a touch input performed on the display unit; and a control unit for executing an application displaying a letter or a picture inputted through the touch input onto the display unit, and executing a function corresponding to the first hand gesture among functions of the application ...

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24-12-2014 дата публикации

COMPOSITION FOR INDUCING CELLULAR SENESCENCE CONTAINING AGENT FOR SUPPRESSING HS2ST1 GENE OR PROTEIN CODIFIED BY THE GENE, AND METHOD FOR INDUCING CELLULAR SENESCENCE USING SAME

Номер: WO2014204024A1
Принадлежит:

The present invention relates to a composition for inducing cellular senescence and a method for inducing cellular senescence using same, wherein the composition can induce cellular senescence by suppressing an HS2ST1 gene in tumor cells and thus can exhibit an anticancer effect in the tumor cells.

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15-06-2017 дата публикации

GENETIC MARKER FOR DISCRIMINATING AND DETECTING CAUSATIVE BACTERIA OF FISH EDWARDSIELLOSIS AND STREPTOCOCCOSIS, AND METHOD FOR DISCRIMINATING AND DETECTING CAUSATIVE BACTERIA USING SAME

Номер: WO2017099445A1
Принадлежит:

The present invention relates to a genetic marker for discriminating and detecting the causative bacteria of fish edwardsiellosis and streptococcosis in fish, and a method for discriminating and detecting the causative bacteria using the same. More specifically, the present invention relates to a method for selecting and amplifying a genetic marker comprising a bacteria-specific single nucleotide polymorphism (SNP) of a DNA base sequence which encodes 16S rDNA genes of Edwardsiella tarda, streptococcal Streptococcus iniae, Streptococcus parauberis and Lactococcus garvieae, which are the causative bacteria of fish edwardsiellosis and streptococcosis in fish, then hybridizing peptide nucleic acids (PNA) which specifically recognize an amplified product, obtaining a melting curve for each temperature through temperature control of the hybridized product, and discriminating bacteria species or detecting whether a fish was infected with the bacteria species from the melting temperature through ...

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03-09-2015 дата публикации

Composition for ameliorating or preventing side effects from radiation therapy and use thereof

Номер: KR0101549667B1
Принадлежит: 한국원자력의학원

... 본 발명은 MAP/미세소관 친화도 조절 키나아제 유전자 및 Raf 키나아제 억제 단백질 유전자로 이루어진 군에서 선택된 하나 이상의 유전자 또는 상기 유전자가 암호화하는 단백질에 대한 억제제를 포함하는 방사선 요법으로 인한 부작용 개선 또는 예방용 조성물에 관한 것으로, 상기 조성물은 종양세포에 대한 방사선 요법으로 인해 종양세포에서 분비된 단백질에 의한 종양세포 및 혈관내피세포의 세포활성도 증가, 종양세포의 세포침윤 증가, 종양세포의 세포이동 증가, 종양세포 및 혈관내피세포의 창상치유 증가 또는 혈관내피세포의 관 형성 증가를 억제함으로써 방사선 요법에 의한 부작용을 억제할 수 있어 항암 보조제로 이용될 수 있다.

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21-11-2016 дата публикации

GENETIC MARKER FOR IDENTIFYING AND DETECTING STREPTOCOCCUS PARAUBERIS, WHICH IS BACTERIAL PATHOGEN ASSOCIATED WITH STREPTOCOCCAL INFECTION, AND METHOD FOR IDENTIFYING AND DETECTING BACTERIAL PATHOGEN USING SAME

Номер: KR101677951B1

The present invention relates to a genetic marker for identifying and detecting a bacterial pathogen associated with streptococcal infection of fishes, and a method for identifying and detecting a bacterial pathogen using the same and, more specifically, to a method for identifying a bacterial species or detecting whether a fish is infected with the same bacterial species or not based on the melting temperature by the following steps: selecting and amplifying a genetic marker including bacterium-specific single nucleotide polymorphism (SNP) among DNA sequences coding 16S rDNA of Streptococcus parauberis, which a bacterial pathogen associated with streptococcal infection of fishes; hybridizing peptide nucleic acid (PNA), which specifically recognizes the amplified product; obtaining a melting profile through temperature control of the hybridized product; and analyzing the obtained melting profile. The present invention selects the genetic marker for identifying and/or detecting Streptococcus ...

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18-05-2017 дата публикации

GENETIC MARKER FOR DETECTING SPRING VIRAEMIA OF CARP VIRUS AND METHOD FOR DETECTING SPRING VIRAEMIA OF CARP VIRUS USING SAME

Номер: KR101737322B1

The present invention relates to a genetic marker for detecting spring viraemia of carp virus (SVCV) and a method for detecting SVCV using the same and, more specifically, to a method for amplifying a specific nucleic acid of the SVCV, hybridizing a peptide nucleic acid (PNA) which specifically recognizes the amplified product, obtaining a temperature-dependent melting curve by controlling the temperature of the hybridized product, and detecting the SVCV or confirming whether a carp is infected with the virus from the melding temperature through the analysis of the obtained melting curve. According to the present invention, as the SVCV is detected simply, quickly and accurately, the infection of the virus recognized as the biggest threat to the carp culture and the spread of the spring viraemia of carp caused by the virus can be prevented early. COPYRIGHT KIPO 2017 ...

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18-08-2015 дата публикации

APPARATUS FOR ADJUSTING COIL AND SUBSTRATE BONDING CHAMBER USING THE SAME

Номер: KR0101544895B1
Принадлежит: 주식회사 엘트린

... 본 발명은 코일조절장치에 관한 것으로, 본 발명에 따른 코일조절장치는, 두 개의 기판을 접합하기 위하여 상기 두 개의 기판을 가열하는 가열판 내의 코일설치공간에 설치되는 것으로, 정중앙을 기준으로 방사상 외측방향의 원주가 일정 비율로 커지는 나선형으로 형성되고, 나선형의 정중앙부분에 위치한 일단과 나선형의 방사상 최외측에 형성된 타단을 포함하는 코일; 상기 코일의 일단과 타단 사이에 결합되는 절연 성질의 지주봉; 및 상기 지주봉 간의 수평 간격 및 수직 간격을 조절하는 위치조절부;를 포함하며, 본 발명에 다른 코일조절장치를 사용함으로써, 코일의 유도가열로 인해 온도가 조절되는 가열판이 균일한 온도로 가열되도록 할 수 있다.

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09-03-2023 дата публикации

건강지수를 통한 체계적인 만성질환을 관리하는 시스템 및 그 제어방법

Номер: KR20230033755A
Принадлежит:

... 본 발명은, 사용자 기본정보와, 사용자의 건강검진 정보와, 사용자의 보험정보를 이용하여, 사용자의 건강지수(건강 위험 지수)를 검출하고, 검출된 건강지수를 토대로, 사용자의 복약관리, 운동관리, 식이관리 등을 행하는, 건강지수를 통한 체계적인 만성질환을 관리하는 시스템 및 그 제어방법에 관한 것이다. 건강지수를 통한 체계적인 만성질환을 관리하는 시스템 및 그 제어방법은, 메인서버는, 고혈압, 당뇨, 고지혈증의 각 질환에 따른, 건강검진 데이터 서버로부터의 건강검진 데이터의 임상수치를, 건강검진 데이터별로 기 설정된 각 등급의 기준범위들에 따라 4개의 등급중 하나로 설정하고, 각 등급에 따라 기 설정된 점수를 부여하는, 건강검진 데이터의 점수 산출단계; 메인서버는, 처방된 약물의 양에서, 사용자 단말기로부터 수신된 복용한 약물의 양을, 분율로 나타낸 복약순응도를, 기 설정된 각 등급의 기준범위들에 따라 3개의 등급으로 나누고, 각 등급에 따라 기 설정된 점수를 부여하는, 제1 복약순응도의 점수 산출단계; 메인서버는, 만성질환의 정도에 따른 분류단계 후, 만성질환별 상대 위험도 산출단계에서 구한 건강검진 데이터의 점수들과, 제1 복약순응도의 점수 산출단계에서 구한 복약순응도의 점수를 이용하여, 각 질환별 위험지수를 검출하고, 각 질환별 위험지수를 합산하여 종합 상대 위험도를 산출하는, 종합 상대 위험도 산출단계; 메인서버는, 보험사 서버로부터의, 보험 보장기간과 보장된 질병명을 포함하는 사용자의 보험정보를 수신하고, 보험정보의 보장된 질병명에서 고혈압, 당뇨, 고지혈증과 동반되는 질병명의 갯수와, 향후 보험 보장기간을, 기 설정된 등급별 기준범위와 비교하여 등급을 부여하고, 부여된 상기 등급에 따라 기설정된 가중치가 부여되는, 보험 보장정도에 따른 가중치 산출단계; 메인서버는, 종합 상대 위험도 산출단계에서 검출된 종합 상대 위험도에 가중치를 곱하여, 가중치를 적용한 종합 상대 위험도로서 출력하는, 가중치를 적용한 종합 상대 위험도 산출단계; 메인서버는, 가중치를 ...

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18-05-2017 дата публикации

GENETIC MARKER FOR DETECTING INFECTIOUS MYONECROSIS VIRUS, AND METHOD FOR DETECTING VIRUS BY USING SAME

Номер: KR101737313B1

The present invention relates to a genetic marker for detecting an infectious myonecrosis virus (IMNV), and to a method for detecting a virus by using the same. More specifically, according to the method of the present invention, a specific nucleic acid of an IMNV is amplified, and a peptide nucleic acid (PNA) for specifically recognizing an amplified product is hybridized. Then, melting curves for each temperature are obtained by adjusting the temperature of a hybridized product, and an IMNV is detected from a melting temperature by analyzing the obtained melting curves or it is confirmed whether a shrimp is infected by the virus. According to the present invention, an IMNV is simply, rapidly, and accurately detected, so infection and diffusion of the virus recognized as the biggest threat in shrimp culture can be blocked in the early stage. COPYRIGHT KIPO 2017 ...

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20-05-2015 дата публикации

ELECTRONIC DEVICE AND METHOD FOR CONTROLLING SAME

Номер: KR1020150054559A
Автор: JUNG, SEUNG HEE
Принадлежит:

The present invention relates to an electronic device and a method for controlling the same. The present invention provides an electronic device and a method for controlling the same to enable the efficient use of a screen with the use of a virtual space when multiple items are executed. According to the present invention, the electronic device comprises: a touch screen to display a first screen relating to a first item; a memory to store information on the location of a virtual space around the touch screen; and a control part to display a second screen relating to a second item on the touch screen when receiving a predetermined touch input on the first screen. COPYRIGHT KIPO 2015 (S110) Displaying a first screen relating to a first item (S120) Receiving a predetermined touch input (S130) Moving the first screen to one area of the virtual space (S140) Displaying a second screen relating to a second item (S100) Store information on the location of a virtual space (BB) End (AA) Start ...

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19-03-2018 дата публикации

COMPOSITION FOR INDUCING CELL SENESCENCE CONTAINING LINC-ASEN EXPRESSION INHIBITOR AS ACTIVE INGREDIENT

Номер: KR1020180028690A
Принадлежит:

The present invention relates to a composition for inducing cell senescence, containing a long intergenic noncoding RNA-associated with senescence (Linc-ASEN) expression inhibitor as an active ingredient. The present invention further relates to a composition for preventing or treating cancer, and an anticancer supplement. According to the present invention, the composition suppresses expression of Linc-ASEN genes in cells, induces senescence of cells, especially in cancer cells, and prevents proliferation of cancer cells, thereby being used as anticancer drugs and anticancer supplements. COPYRIGHT KIPO 2018 (AA) Two days (BB) Four days ...

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18-05-2017 дата публикации

GENETIC MARKER FOR DETECTING EXTRA SMALL VIRUS, AND METHOD FOR DETECTING VIRUS BY USING SAME

Номер: KR101737316B1

The present invention relates to a genetic marker for detecting an extra small virus (XSV), and to a method for detecting a virus by using the same. More specifically, according to the method of the present invention, a specific nucleic acid of an XSV is amplified, and a peptide nucleic acid (PNA) for specifically recognizing an amplified product is hybridized. Then, melting curves for each temperature are obtained by adjusting the temperature of a hybridized product, and an XSV is detected from a melting temperature by analyzing the obtained melting curves or it is confirmed whether a shrimp is infected by the virus. According to the present invention, an XSV is simply, rapidly, and accurately detected, so infection of the virus and diffusion of white tail disease caused by the virus, which are recognized as the biggest threat in shrimp culture, can be blocked in the early stage. COPYRIGHT KIPO 2017 ...

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20-10-2022 дата публикации

마음을 표현하는 다면체 놀이장치

Номер: KR20220141578A
Автор: 정승희
Принадлежит:

... 본 발명은 다수의 측면을 가지는 회전체를 수개 적층하고, 상기 회전체의 측면부에는 서로 다른 형태의 눈, 코, 입 모양이 디자인 되어 있어, 상기 회전체를 각각 회전시키는 것에 의해 일면에 자신이 원하는 표정을 가진 이모티콘 형상을 조합 표현할 수 있도록 함으로써, 이를 통해 재미있는 무언의 의사표시가 가능하고 동시에 이를 이용한 다양한 놀이나 오락 등을 할 수 있는 마음을 표현하는 다면체 놀이장치에 관한 것으로, 다수의 측면을 가지는 회전체와, 상기 회전체를 다수개 적층하되 각각 회전가능하도록 결합하여 주는 회전축부를 포함하고, 상기 회전체는 제1회전체, 제2회전체 및 제3회전체가 상부로부터 순차적으로 적층되도록 하되, 상기 제1회전체의 다수개의 측면부에는 서로 다른 형태의 눈 모양이 각각 디자인 된 상태로 구성되고, 상기 제2회전체의 다수개의 측면부에는 서로 다른 형태의 코 모양이 각각 디자인 된 상태로 구성되고, 상기 제3회전체의 다수개의 측면부에는 서로 다른 형태의 입 모양이 각각 디자인 된 상태로 구성된 것을 특징으로 한다.

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23-06-2016 дата публикации

GENETIC MARKER FOR DETERMINING PATHOGENICITY OF STREPTOCOCCUS INIAE AND KIT FOR EXAMINING DETERMINANT MARKERS OF PATHOGENICITY BY USING PEPTIDE NUCLEIC ACID

Номер: WO2016098953A1
Принадлежит:

The present invention relates to a probe for determining a genotype of Steptococcus iniae, the probe being capable of hybridizing, under strict conditions, with a sequence fragment containing a single nucleotide polymorphism variation of T368C or T385G in the cpsD sequence, which is represented by SEQ ID NO: 1, of Streptococcus iniae and, more particularly, to a kit which allows each genotype influencing pathogenicity to have different melting temperature by using a peptide nucleic acid (PNA) having an excellent binding ability to DNA, thereby enabling a simple, rapid, and accurate determination of the pathogenicity of S. iniae.

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11-10-2018 дата публикации

VACCINE COMPOSITION COMPRISING VHSV VACCINE AND ADJUVANT

Номер: WO2018186522A1
Принадлежит:

The present invention relates to an immersion vaccine composition for preventing viral hemorrhagic septicemia of fish containing a VHSV vaccine and Montanide IMS 1312 VG adjuvant, and a method for preventing viral hemorrhagic septicemia of fish using the same. The use of the immersion vaccine for viral hemorrhagic septicemia according to the present invention can effectively prevent viral hemorrhagic septicemia in fish that are difficult to inoculate.

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16-11-2016 дата публикации

COMPOSITION FOR INHIBITING TUMOR CELL SENESCENCE, COMPRISING Src INHIBITOR

Номер: KR1020160131253A
Принадлежит:

The present invention relates to a composition for inhibiting tumor cell senescence, comprising an Src inhibitor, and relates to a method for controlling the senescence of a tumor cell using the inhibitor. According to the present invention, the composition inhibits the expression or the activation of Src in the tumor cell, thereby inhibiting the senescence of the tumor cell induced by the radiation. Accordingly, the effects of a specific substance on the expression or the activation of the Src is analyzed, thereby performing the research of an anticancer mechanism related to the increase in the sensitivity of the tumor cells with respect to the radiation. COPYRIGHT KIPO 2016 (A1.A2) Control group (B1,B2) Radiation (CC) SRC activity inhibitor (PP2) (DD) Cell morphology change (EE) Beta-galactosidase activity (FF) Cell aging-related beta-galactosidase activation (GG) Control group + Radiation (HH) SRC activity inhibitor + Radiation ...

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06-02-2024 дата публикации

FLT3 매개된 질환의 예방 또는 치료용 약학적 조성물

Номер: KR20240016479A
Принадлежит:

... 신규한 화합물, 티로신 키나아제인 FLT3 저해 용도, 및 이의 FLT3 매개된 질환, 예를 들어, 조혈 질환 또는 암의 예방 또는 치료 용도를 제공한다. 이에 따르면, 상기 화합물이 FLT3 키나아제 활성을 저해할 수 있어, FLT3 키나아제가 관여하는 다양한 조혈 질환 또는 암의 예방 또는 치료에 효능을 나타낼 수 있다.

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23-03-2017 дата публикации

Src 억제제를 포함하는 종양세포 노화 억제용 조성물

Номер: KR0101719229B1
Принадлежит: 인하대학교 산학협력단

... 본 발명은 Src 억제제를 포함하는 종양세포 노화 억제용 조성물 및 상기 억제제를 이용한 종양세포의 노화 조절 방법에 관한 것이다. 본 발명에 따른 조성물은 종양세포에서 Src의 발현 또는 활성을 억제하여 방사선에 의해 유도된 종양 세포의 노화를 억제할 수 있다. 따라서 특정 물질이 Src의 발현 또는 활성에 미치는 영향을 분석함으로써 방사선에 대한 종양세포의 민감성 증진과 관련된 항암 기작의 연구가 가능하다.

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17-03-2016 дата публикации

COMBINED INACTIVATED VACCINE AGAINST BACTERIAL DISEASES IN FISH COMPRISING ANTIGEN ORIGINATED FROM STREPTOCOCCUS PARAUBERIS AND PREVENTION METHOD OF BACTERIAL DISEASES IN FISH USING IT

Номер: KR0101603714B1
Принадлежит: 대한민국

... 본 발명은 넙치로부터 분리된 알파-용혈성 스트렙토코커스 파라우베리스(Streptococcusparauberis) FPA4164 균주(KCTC 11980BP) 균주 및 이를 이용한 어류의 세포성 질병 예방용 혼합 불활성화 백신에 관한 것으로서, 본 발명의 백신은 1회 투여로 3 종류의 세균에 의한 질병을 효과적으로 그리고 경제적으로 예방할 수 있으므로, 어류의 양식 산업 등에 유용하게 사용될 수 있다.

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23-09-2022 дата публикации

단백질 키나제 억제제로서의 헤테로고리 화합물의 신규 염 및 이들의 용도

Номер: KR20220129494A
Принадлежит:

... 본 발명은 단백질 키나제 억제제로서의 헤테로고리 화합물의 신규 염 및 이들의 용도에 관한 것으로, 신규 염은 수용해도가 우수하고, 물리적, 화학적 안정성이 우수하여 의약품의 제제화에 유용하게 활용될 수 있다. 또한, 헤테로고리 화합물 또는 이들의 염은 아토피성 피부염 및 염증성 장질환을 각각 효과적으로 치료 및 예방할 수 있다.

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29-07-2022 дата публикации

개인 단말기 측정 정보 기반의 개인 생체리듬 맞춤형 약물 섭취 정보의 제공 및 관리 시스템

Номер: KR20220106714A
Принадлежит:

... 본 발명은 개인 단말기(IT 디바이스)로부터 개인의 활동데이터, 생체정보 등을 메인서버가 수신하고, 수신된 개인의 활동데이터, 생체정보의 패턴을 분석하여 일주기 생체 리듬을 산출하고, 산출된 일주기 생체 리듬과, 개인의 성별, 나이, 키, 몸무게를 이용하여, 개인별로, 질병의 예방, 치유 또는 건강관리 및 증진의 목적 등으로 복용해야하는 약물 섭취 정보(복용 약물 종류, 복용시점, 복용기간, 복용량 등)를 생성하고, 생성된 약물 섭취 정보를 개인 단말기로 전송하고, 개인 단말기는 복용 시기에 알람을 행하고, 복용 여부 확인 메시지 등을 통해 복용여부를 확인 관리하는, 개인 단말기 측정 정보 기반의 개인 생체리듬 맞춤형 약물 섭취 정보의 제공 및 관리 시스템에 관한 것이다. 본 발명의 개인 생체리듬 맞춤형 약물 섭취 정보의 제공 및 관리 시스템은, 움직임 감지 센서 및 조도센서를 포함하여 움직임 신호와 조도 신호를 검출하고, 움직임 신호와 조도 신호를 활동 정보로써 메인서버로 전송하는, 개인 단말기; 개인 단말기로부터 수신된 활동정보를 이용하여 생체리듬을 검출하고, 검출된 생체리듬과, 사용자의 성별, 나이, 키, 몸무게로 이루어진 개인정보을 기 학습된 인공지능망에 입력하고, 인공지능망으로부터 출력되는, 약물복용 시점을 포함하는 약물 섭취정보를 개인 단말기로 전송하는, 메인서버;를 포함하는 것을 특징으로 한다. 본 발명은, 사용자별로 24시간 생체리듬을 고려하여 약물이 가장 효과적으로 반응하는 시점을 파악하고, 그 시점에, 사용자로 하여금, 집중적으로 투약하게 하여 약물의 효과를 극대화되게 한다.

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27-11-2014 дата публикации

COMPOSITION FOR INDUCING TUMOR CELL SENESCENCE COMPRISING PAPSS2 GENE OR INHIBITOR AGAINST PROTEIN ENCODED BY GENE AND METHOD FOR INDUCING TUMOR CELL SENESCENCE USING SAME

Номер: WO2014189156A1
Принадлежит:

The present invention relates to a composition for inducing tumor cell senescence and a method for inducing tumor cell senescence using the same. The composition can inhibit a PAPSS2 gene in a tumor cell to thereby induce senescence of the tumor cell, and if the composition is used concurrently with irradiation of the tumor cell, the composition can improve the sensitivity of the tumor cell to radiation ...

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28-09-2016 дата публикации

COMPOSITION FOR INHIBITING TUMOR CELL SENESCENCE, COMPRISING ITGB4 INHIBITOR

Номер: KR1020160112274A
Принадлежит:

The present invention relates to a composition for inhibiting tumor cell senescence, comprising an integrin beta 4 (ITGB4) inhibitor, and relates to a method for controlling the senescence of tumor cells using the inhibitor. According to the present invention, the composition can inhibit the senescence of tumor cells induced by radiation by inhibiting the expression or the activation of ITGB4 in the tumor cells. Accordingly, the research of anticancer mechanism related to the enhanced sensitivity of the tumor cells with respect to the radiation can be performed by analyzing the specific substance having effects in expressing or activating ITGB4. COPYRIGHT KIPO 2016 (AA) ITGB4 activity inhibitor (Asc-8) (B1,B2) Control group (CC) Cell form change (DD) Beta-galactosidase activity (E1,E2) Radiation (FF) Senescence of cell-related beta-galactosidase activity (GG) Control group + radiation (HH) ITGB4 activity inhibitor + radiation ...

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18-07-2016 дата публикации

TOUCH SENSOR DEVICE AND DISPLAY DEVICE INCLUDING TOUCH SENSOR DEVICE

Номер: KR1020160085400A
Принадлежит:

The present invention is to provide a touch sensor device capable of precisely recognizing a touch position and a display device including the same. The touch sensor device comprises: a plurality of first sensing electrodes which includes a plurality of first linear electrodes extending in a first direction and a first connection electrode connecting the first linear electrodes to each other; and a plurality of second sensing electrodes which include a plurality of second linear electrodes extending in a second direction vertical to the first direction and a second connection electrode connecting the second linear electrodes to each other, wherein disposition density of the first linear electrodes belonging to one first sensing electrode is gradually decreased as going from the center to the outside of the first sensing electrode. COPYRIGHT KIPO 2016 ...

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08-12-2022 дата публикации

고혈압을 동반한 당뇨병성 신장질환의 예방 또는 치료용 약학적 조성물

Номер: KR20220162456A
Принадлежит:

... 본 발명의 약학적 조성물은 고혈압을 동반한 당뇨병성 신장질환의 발병을 미연에 차단, 억제 또는 지연시키거나 고혈압을 동반한 당뇨병성 신장질환을 개선 또는 진행을 억제하여 고혈압을 동반한 당뇨병성 신장질환을 효과적으로 예방 또는 치료할 수 있다.

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11-08-2011 дата публикации

SUBSTRATE BONDING SYSTEM AND MOBILE CHAMBER USED THERETO

Номер: KR2011096638A1
Принадлежит:

The present invention relates to a substrate bonding system comprising: a mobile chamber that accommodates one pair of arranged substrates; a conveyor moving device that continuously moves the mobile chamber, and is provided with a vacuum generator which is connected to a vacuum port of the mobile chamber and vacuumizes the inside of the mobile chamber; and a heating device that performs a heating process in which one pair of the arranged substrates are bonded within the mobile chamber, wherein the conveyor moving device is arranged to pass through the heating device. According to the present invention, the substrate bonding system increases accuracy in bonding and miniaturizes the size of the chamber, thereby easily utilizing a space. Further, since the bonding process is continuously progressed by using the conveyor moving device, the process time is reduced.

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02-05-2018 дата публикации

Linc-ASEN 발현 억제제를 유효성분으로 포함하는 세포 노화 유도용 조성물

Номер: KR0101853731B1
Принадлежит: 인하대학교 산학협력단

... 본 발명은 Linc-ASEN 발현 억제제를 유효성분으로 포함하는 세포 노화 유도용 조성물, 암 예방 또는 치료용 조성물 및 항암보조제에 관한 것이다. 본 발명에 따른 조성물은 세포에서 Linc-ASEN(Long intergenic noncoding RNA-Associated with Senescence) 유전자의 발현을 억제하여 세포의 노화, 특히 암세포에서 노화를 유도할 수 있으며, 이를 통하여 암세포의 증식을 억제할 수 있는바, 항암제 및 항암보조제 등으로 사용할 수 있다.

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20-03-2017 дата публикации

이동단말기 및 그의 잠금 해제 방법

Номер: KR0101718025B1
Автор: 정승희
Принадлежит: 엘지전자 주식회사

... 본 발명은 이동단말기 및 그의 잠금 해제 방법에 관한 것으로, 본 발명에 따른 실시 예들은 사전에 3차원 패턴 또는 터치시간을 이용한 2차원 패턴을 잠금 해제 패턴으로 등록하고, 잠금 상태에서 터치스크린 상에 입력되는 패턴을 인식하고, 그 인식된 패턴이 기설정된 잠금 해제 패턴과 일치하는지를 확인하여 그 확인결과에 따라 잠금 상태를 해제하거나 유지한다.

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23-08-2017 дата публикации

EYEGLASSES SENSING STATE OF TRAFFIC LIGHTS

Номер: KR1020170095426A
Принадлежит:

The present invention relates to eyeglasses sensing a state of traffic lights. The eyeglasses sensing the state of the traffic lights includes: a frame wherein lenses are mounted; a pair of temples connected to the frame; and a traffic light sensing device mounted on one of the temples. The traffic light sensing device includes: a traffic light frequency sensing unit sensing a size of a frequency outputted from the traffic lights, determining whether a traffic light currently lit up is red or green based on the sensed size of the frequency, and outputting corresponding determination signals; a voice output control unit connected to the traffic light frequency sensing unit, determining whether the traffic light currently lit is red or green in accordance with the determination signals applied from the traffic light frequency sensing unit, and outputting corresponding voice signals in accordance with the determined traffic light; and a voice outputting unit connected to the voice output control ...

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25-10-2017 дата публикации

COMPOSITION CONTAINING IVERMECTIN FOR PREVENTING CLAVINEMA MARIAE INFECTION OF SEBASTES SCHLEGELI

Номер: KR101789736B1

The present invention relates to a composition containing ivermectin for preventing Clavinema mariae infection of Sebastes schlegeli and, more specifically, to a composition containing ivermectin as an active ingredient for preventing Clavinema mariae infection of Sebastes schlegeli and to a method for preventing Clavinema mariae infection of Sebastes schlegeli through oral administration of ivermectin to Sebastes schlegeli. The composition and the prevention method according to the present invention have excellent prevention effects of Clavinema mariae infection of Sebastes schlegeli and are safe without side effects to Sebastes schlegeli. In addition, oral administration is possible so the composition can be usefully used in the aquaculture industry. COPYRIGHT KIPO 2017 ...

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06-10-2011 дата публикации

COMBINED INACTIVATED VACCINE FOR PREVENTION OF STREPTOCOCCICOSIS OF FISH AND METHOD FOR PREPARING SAME

Номер: WO2011122843A3
Принадлежит:

The present invention relates to a combined inactivated vaccine for prevention of streptococcicosis, comprising gamma-hemolytic Streptococcus parauberis FP2284 (microorganism deposition number KCTC 11633BP) strain isolated from the flounder infected with streptococcicosis, and beta-hemolytic Streptococcus iniae FP5024 (microorganism deposition number 11634BP) strain isolated from the flounder infected with streptococcicosis. The present invention also relates to a method for immunizing the fish using said vaccine.

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08-10-2018 дата публикации

COMPOSITION FOR TREATING OR PREVENTING ACUTE HEPATOPANCREATIC NECROSIS OF SHRIMP

Номер: KR101904371B1

The present invention relates to a composition for treating or preventing acute hepatopancreatic necrosis of shrimp comprising an ethanol extract of a herbal medicinal product comprising Artemisia iwayomogi and/or Angelica gigas as an active ingredient. The composition and the treatment or prevention method according to the present invention are excellent in an effect of killing or inhibiting the proliferation of Vibrio parahaemolyticus of shrimp, are excellent in the treatment and prevention of acute hepatopancreatic necrosis of shrimp, are safe as herbal components with no side effects on shrimp, and can be orally administered together with feed, thereby being usefully used in the aquaculture industry. COPYRIGHT KIPO 2018 (AA) Artemisia iwayomogi (BB) Angelica gigas Nakai (CC) Artemisia iwayomogi and Angelica gigas Nakai ...

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18-05-2017 дата публикации

GENETIC MARKER FOR DETECTING MACROBRACHIUM ROSENBERGII NODAVIRUS, AND METHOD FOR DETECTING VIRUS BY USING SAME

Номер: KR101737314B1

The present invention relates to a genetic marker for detecting a Macrobrachium rosenbergii nodavirus (MrNV), and to a method for detecting a virus by using the same. More specifically, according to the method of the present invention, a specific nucleic acid of an MrNV is amplified, and a peptide nucleic acid (PNA) for specifically recognizing an amplified product is hybridized. Then, melting curves for each temperature are obtained by adjusting the temperature of a hybridized product, and an MrNV is detected from a melting temperature by analyzing the obtained melting curves or it is confirmed whether a shrimp is infected by the virus. According to the present invention, an MrNV is simply, rapidly, and accurately detected, so infection and diffusion of the virus recognized as the biggest threat in shrimp culture can be blocked in the early stage. COPYRIGHT KIPO 2017 ...

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04-08-2016 дата публикации

GENETIC MARKER FOR DISCRIMINATING AND DETECTING CAUSATIVE BACTERIA OF EDWARDSIELLOSIS AND STREPTOCOCCOSIS, AND METHOD FOR DISCRIMINATING AND DETECTING CAUSATIVE BACTERIA USING SAME

Номер: KR101644773B1

The present invention relates to a genetic marker for discriminating and detecting causative bacteria of edwardsiellosis and streptococcosis, and relates to a method for discriminating and detecting causative bacteria using the same. More specifically, the present invention relates to a genetic marker for discriminating or detecting Edwardsiella tarda represented by a base sequence of SEQ ID NO: 8. The genetic marker for discriminating and detecting edwardsiellosis and streptococcosis and the method for discriminating and detecting causative bacteria using the same can discriminate the causative bacteria of fish diseases in a simple, rapid, and accurate manner, and have effects in detecting whether the fish is infected with the bacteria. COPYRIGHT KIPO 2016 ...

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07-10-2016 дата публикации

ITGB4 억제제를 포함하는 종양세포 노화 억제용 조성물

Номер: KR0101663567B1
Принадлежит: 인하대학교 산학협력단

... 본 발명은 ITGB4(integrin beta 4) 억제제를 포함하는 종양세포 노화 억제용 조성물 및 상기 억제제를 이용한 종양세포의 노화 조절 방법에 관한 것이다. 본 발명에 따른 조성물은 종양세포에서 ITGB4의 발현 또는 활성을 억제하여 방사선에 의해 유도된 종양 세포의 노화를 억제할 수 있다. 따라서 특정 물질이 ITGB4의 발현 또는 활성에 미치는 영향을 분석함으로써 방사선에 대한 종양세포의 민감성 증진과 관련된 항암 기작의 연구가 가능하다.

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18-05-2017 дата публикации

GENETIC MARKER FOR DETECTING YELLOW HEAD VIRUS 1, AND METHOD FOR DETECTING VIRUS BY USING SAME

Номер: KR101737318B1

The present invention relates to a genetic marker for detecting a yellow head virus 1 (YHV1), and to a method for detecting a virus by using the same. More specifically, according to the method of the present invention, a specific nucleic acid of an YHV1 is amplified, and a peptide nucleic acid (PNA) for specifically recognizing an amplified product is hybridized. Then, melting curves for each temperature are obtained by adjusting the temperature of a hybridized product, and an YHV1 is detected from a melting temperature by analyzing the obtained melting curves or it is confirmed whether a shrimp is infected by the virus. According to the present invention, an YHV1 is simply, rapidly, and accurately detected, so infection of the virus and diffusion of yellow head disease caused by the virus, which are recognized as the biggest threats in shrimp culture, can be blocked in the early stage. COPYRIGHT KIPO 2017 ...

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24-06-2015 дата публикации

GENETIC MARKER FOR IDENTIFYING VIRULENCE OF STREPTOCOCCUS INIAE AND MARKER TEST KIT FOR DETERMINING VIRULENCE USING PEPTIDE NUCLEIC ACIDS

Номер: KR101531296B1

The present invention relates to a probe for identifying a genotype of Streptococcus iniae capable of hybridizing with fragment sequences, which includes a T368C or T385G single nucleotide polymorphism mutation in a cpsD sequence of SEQ ID NO: 1 Streptococcus iniae under stringent conditions, and more specifically, relates to a kit for identifying the virulence of Streptococcus inae simply, quickly, and precisely by allowing genotypes affecting the virulence to exhibit a different melting temperature for each genotype using peptide nucleic acids (PNA) with excellent coherence with DNA. COPYRIGHT KIPO 2015 ...

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22-02-2017 дата публикации

COMPOSITION CONTAINING MIXED HERB EXTRACT FOR PREVENTING OR TREATING INFECTION OF FISH PATHOGENIC MICROORGANISM

Номер: KR101709169B1

The present invention relates to a composition containing a mixed herb extract for preventing or treating infection of fish pathogenic microorganism. More specifically, the present invention relates to the composition containing the mixed herb extract for preventing or treating the infection of fish pathogenic microorganism in order to produce aquatic culture products for preventing diseases of cultured organisms and eco-friendly aquatic culture products as medicines for fisheries with herbal components which are superior in replacement of antibiotics. The composition containing the mixed herb extract as an active ingredient for preventing or treating the infection of fish pathogenic microorganism can be used practically for preventing or treating the diseases of the aquatic culture products for the medicines for fisheries with the herbal components which are superior in replacement of antibiotics. COPYRIGHT KIPO 2017 (AA) Grill (BB) Intestine (CC) Kidney (DD) Liver (EE) Spleen (FF) Heart ...

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22-11-2016 дата публикации

FISH VACCINE FOR PREVENTING SCUTICOCILIATES

Номер: KR101677947B1

The present invention relates to a method for producing fish vaccine against scuticociliates, comprising the steps of: culturing scuticociliates; adding formalin to the culture and reacting the same; and obtaining a scuticociliates inactivated liquid from the formalin-added culture. COPYRIGHT KIPO 2016 ...

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21-11-2016 дата публикации

GENETIC MARKER FOR IDENTIFICATION AND DETECTION OF STREPTOCOCCUS INIAE, WHICH IS BACTERIAL PATHOGEN ASSOCIATED WITH STREPTOCOCCAL INFECTION, AND METHOD FOR IDENTIFICATION AND DETECTION OF BACTERIAL PATHOGEN USING SAME

Номер: KR101677948B1

The present invention relates to a genetic marker for the identification and detection of a bacterial pathogen causing streptococcal infection of fishes, and to a method for the identification and detection of the bacterial pathogen using the same, and more specifically, to a method for identifying a bacterial species or detecting whether a fish is infected with the same bacterial species or not based on the melting temperature by: selecting a genetic marker containing the bacterium-specific single nucleotide polymorphism (SNP) of DNA sequences encoding 16S rDNA of Streptococcus iniae, which is a bacterial pathogen causing streptococcal infection of fishes, and amplifying the same; hybridizing peptide nucleic acid (PNA) specifically recognizing the amplified product; obtaining a melting profile by temperature through the temperature control of the hybridized product; and analyzing the obtained melting profile. The present invention is effective in identifying a bacterial pathogen causing ...

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24-12-2014 дата публикации

MARKER FOR DIAGNOSING CELLULAR SENESCENCE AND USES THEREOF

Номер: WO2014204025A1
Принадлежит:

The present invention relates to a marker for diagnosing cellular senescence and uses thereof. A PAPSS2 gene is capable of performing the role of the marker for diagnosing cellular senescence and thus can be used in a method for diagnosing aging cells, a method for screening a composition for inducing cellular senescence, and a method for screening a composition for suppressing cellular senescence, among others. Also, senescence of non-tumor cells can be induced when the PAPSS2 gene is suppressed in the non-tumor cells.

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06-10-2011 дата публикации

COMBINED INACTIVATED VACCINE FOR PREVENTION OF STREPTOCOCCICOSIS OF FISH AND METHOD FOR PREPARING SAME

Номер: WO2011122843A2
Принадлежит:

The present invention relates to a combined inactivated vaccine for prevention of streptococcicosis, comprising gamma-hemolytic Streptococcus parauberis FP2284 (microorganism deposition number KCTC 11633BP) strain isolated from the flounder infected with streptococcicosis, and beta-hemolytic Streptococcus iniae FP5024 (microorganism deposition number 11634BP) strain isolated from the flounder infected with streptococcicosis. The present invention also relates to a method for immunizing the fish using said vaccine.

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30-01-2023 дата публикации

프로바이오틱스의 장기 배양공법

Номер: KR20230014515A
Принадлежит:

... 본 발명은 프로바이오틱스의 장기 배양공법에 관한 것으로, 상기 프로바이오틱스 장기 배양 방법 (Long-Term Fermentation)은 종래 프로바이오틱스 배양 기간에 비하여, 프로바이오틱스를 장기간 배양함으로써 프로바이오틱스의 장 세포 부착 능력을 증가 시키고, 장벽강화 기능을 나타내는 밀착연접단백질의 증가, 구체적으로는 ZO-1, 오클루딘 (Occludin, OCLN), CLDN1 및 CLDN3 중 어느 하나 이상의 발현을 증가시킬 수 있으며, 산성 환경에 노출시켜 산과 담즙에 대한 적응성이 증가, 구체적으로 구강, 위산, 소/대장에서의 생존율을 증가시킬 수 있다.

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07-03-2023 дата публикации

아이스플랜트 추출물, 갈화 추출물, 및 쑥 추출물을 포함하는 숙취해소 및 간 기능 개선용 식품조성물

Номер: KR102506958B1
Принадлежит: 주식회사 에치와이

... 본 발명은 아이스플랜트 (Mesembryanthemum crystalinum) 추출물, 갈화 (Pueraria lobata flower) 추출물, 및 쑥 (Artemisia indica) 추출물을 포함하는 식품조성물에 관한 것으로, 본 발명의 식품조성물을 섭취하면 알코올 대사를 촉진시키고, 알코올로부터 간세포를 보호하므로 숙취를 억제하고 및 간 기능을 보호하는 효과가 있다.

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29-12-2020 дата публикации

Composition for Fish Vaccine Containing Alginate Capsule and Preparing Method Thereof

Номер: KR102196572B1

The present invention relates to an oral vaccine composition for fish comprising sodium alginate capsules in which inactivated pathogenic bacteria are collected, a method for manufacturing the same, and a method for preventing or treating pathogenic bacterial infections of fish including the administration of the oral vaccine composition for fish to the fish. By using the oral vaccine composition according to the present invention, it is possible to easily administer a vaccine to fish, thereby contributing to the efficient prevention of streptococcal disease in fish.

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