04-05-2017 дата публикации
Номер: WO2017074043A1
Принадлежит:
The present invention relates to a composition containing cells, cultured by adding 15-PGDH inhibitor to PGE2-expressing cells, or a culture thereof and a use thereof. More specifically, the present invention relates to: a pharmaceutical composition, containing cells, cultured by adding 15-PGDH inhibitor to PGE2-expressing cells, or a culture thereof, for the prevention or treatment of immunological diseases, inflammatory diseases, or wounds; a method for inhibiting an immune response, an inflammatory response, or wounds in a subject, the method comprising a step for administering the pharmaceutical composition, or the cells or the culture thereof, to the subject; a method for preparing an immunosuppressive agent, an antiinflammatory agent, or a wound healing agent, using the cells or the culture thereof; a method for preparing PGE2, the method comprising a step for adding a 15-PGDH inhibitor to PGE2-expressing cells, followed by culturing; an implant comprising PGE2-expressing cells and ...
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