02-07-2020 дата публикации
Номер: WO2020139044A1
Автор:
PARK, Ki Cheong,
CHEONG, Jae Ho,
KIM, Seok Mo,
RYU, Tae Hi,
YUN, Yeo Jin,
KIM, Byeong Mo
Принадлежит:
The present invention relates to a novel compound and a pharmaceutical composition comprising same for enhancing anticancer activity, and more specifically, by comprising a compound represented by chemical formula 1 or a pharmaceutically acceptable salt thereof, the anticancer activity of an anticancer agent or radiation can be enhanced, and by suppressing the proliferation of cancer cells and inducing apoptosis thereof, cancer can be treated effectively. [Chemical formula 1] In the chemical formula 1: n is an integer of 0 to 4; R1 is hydrogen, C1-C10 alkyl, or aryl(C1-C4)alkyl; R3 is C1-C6 alkyl, wherein the R3, if a plurality thereof is present, are identical or different from each other; L1 is a direct bond or C1-C6 alkylene; R2 is hydrogen, C1-C10 alkyl, or aryl(C1-C4)alkyl; and R4 is hydrogen, C1-C4 alkyl, C3-C8 cycloalkyl, or aryl(C1-C4)alkyl, or R2 and R4 are connected to each other, forming a 4- to 7-membered ring.
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