04-10-2012 дата публикации
Номер: WO2012134188A3
Автор:
CHO, Young Lag,
BAEK, Sung Yoon,
CHAE, Sang Eun,
KIM, Sun Young,
LEE, Hong Bum,
LEE, Hyang Sook,
OH, Kyuman,
HEO, Hye Jin,
PARK, Tae Kyo,
WOO, Sung Ho,
KIM, Yong Zu
Принадлежит:
The present invention relates to a novel oxazolidinone derivative indicated as chemical formula 1 on the description, and in particular, to a novel oxazolidinone compound having a cyclic amidoxime or a cyclic amidrazone group. In the chemical formula 1, R and Q are identical to as defined in the detailed explanation. In addition, the present invention relates to an antibiotic medical compound having the novel oxazolidinone derivative of the chemical formula 1, a prodrug thereof, a hydrate thereof, a solvate thereof, an isomer thereof, and a pharmaceutically permitted salt thereof, as active ingredients. The novel oxazolidinone derivative of the present invention, the prodrug thereof, the hydrate thereof, the solvate thereof, the isomer thereof, and the pharmaceutically permitted salt thereof, have a wide antibacterial spectrum for resistant bacteria, have low toxicity, and show strong antibacterial effect on gram positive and gram negative bacteria, and is thereby useful as an antibiotic ...
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