04-12-2018 дата публикации
Номер: KR101924786B1
Автор:
PARK, SUCK YONG,
JI, HYUN KU,
CHOI, JU HWAN,
HEO, CHAN,
BANG, MIN HYUK,
CHOI, SUNG UP
The present invention relates a pharmaceutical composition for injection of ibuprofen, comprising ibuprofen or a pharmaceutically acceptable salt thereof, and meglumine, and more specifically, to an injectable pharmaceutical composition comprising ibuprofen or a pharmaceutically acceptable salt, and meglumine as a solvent, and an EDTA salt as a stabilizer. The pharmaceutical composition according to the present invention comprises an ibuprofen solvent and a liquid solution of ibuprofen, and by including a stabilizer in the solution, may improve the stability of an ibuprofen preparation. Accordingly, the ibuprofen preparation, even when diluted to an administrable concentration for convenient use prior to being stored, does not suffer decomposition and pH changes, thus preventing the efficacy of drug from decreasing due to a decrease in the content of ibuprofen. According to the present invention, an injectable liquid ibuprofen preparation may be stably stored. COPYRIGHT KIPO 2019 ...
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