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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 12. Отображено 12.
21-11-2019 дата публикации

FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF

Номер: WO2019218876A1
Автор: ZHU, Linyong, YANG, Yi, BAO, Bingkun, SU, Ni, ZHANG, Dasheng, CHEN, Xianjun, LIN, Qiuning, BAO, Chunyan
Принадлежит:

A fluorescent probe and a preparation method and use thereof. The fluorescent probe responds sensitively to viscosity, is specific, and can be used for specific fluorescent labeling of a protein. The fluorescent probe can also be used for protein quantification and detection, for study of protein dynamics, and for imaging of cells, tissues, and living organisms.

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Номер записи: 1
23-05-2019 дата публикации

PREPARATION, RAW MATERIALS, PRODUCT, AND APPLICATION OF PHOTOCROSSLINKED HYDROGEL MATERIAL

Номер: WO2019095599A1
Автор: ZHU, Linyong, HUA, Yujie, LIN, Qiuning, ZHANG, Yiqing, BAO, Chunyan, ZHONG, Xuepeng
Принадлежит:

A photocrosslinked hydrogel material. The material is prepared by: dissolving a component A, a photosensitive polymer derivative, in a biocompatible medium to obtain a photosensitive polymer solution A; dissolving a component B, a photoinitiator, in the biocompatible medium to obtain a photoinitiator solution B; dissolving an auxiliary component C, another biocompatible polymer derivative, in the biocompatible medium to obtain a polymer solution C; and uniformly mixing the solution A and the solution B (or adding the solution C) to obtain a hydrogel precursor solution, and irradiating the hydrogel precursor solution with a light source, such that the hydrogel precursor solution is photocrosslinked to form a hydrogel. The hydrogel system features fast photocuring speed, strong tissue adhesion, excellent mechanical properties, good biocompatibility, and excellent clinical operation. The present invention further relates to a kit for the preparation of the hydrogel, as well as applications ...

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Номер записи: 2
25-01-2018 дата публикации

FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF

Номер: WO2018014821A1
Автор: ZHU, Linyong, YANG, Yi, ZHANG, Dasheng, DU, Zengmin, BAO, Bingkun, LIN, Qiuning, CHEN, Xianjun, YANG, Lipeng, BAO, Chunyan, GE, Yihui, LIU, Renmei, CHEN, Zhengda, ZHANG, Sitong, LI, Ningfeng, HUA, Xin
Принадлежит:

Provided are a fluorescent probe and a preparation method and use thereof. The fluorescent probe is sensitive and specific to a viscosity response, can be used for specific fluorescence labelling of a protein, and can also be used for the quantification, detection or kinetic study of a protein, and the imaging of a cell, a tissue and a living body.

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Номер записи: 3
13-12-2018 дата публикации

FLUORESCENT PROBE, PREPARATION METHOD THEREFOR, AND USE THEREOF

Номер: WO2018223876A1
Автор: ZHU, Linyong, YANG, Yi, ZHANG, Dasheng, LIU, Renmei, BAO, Bingkun, LIN, Qiuning, CHEN, Xianjun, YANG, Lipeng, BAO, Chunyan, GE, Yihui, ZHANG, Chenxia, CHEN, Zhengda, ZHANG, Sitong, LI, Ningfeng, HUA, Xin
Принадлежит:

Provided are a fluorescent probe, a preparation method and application thereof. The fluorescent probe is an addition-activation probe and can be used for specific fluorescent protein labeling, and can also be used for protein quantification, detection, dynamics, activity research, cell, tissue and in vivo images.

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Номер записи: 4
23-05-2019 дата публикации

PREPARATION, RAW MATERIALS, PRODUCT, AND APPLICATION OF PHOTOCOUPLED SYNERGISTIC CROSSLINKED HYDROGEL MATERIAL

Номер: WO2019095600A1
Автор: ZHU, Linyong, HUA, Yujie, LIN, Qiuning, ZHANG, Yiqing, BAO, Chunyan, ZHONG, Xuepeng
Принадлежит:

Provided are preparation, raw materials, a product, and an application of a photocoupled synergistic crosslinked hydrogel material. The material is prepared by: dissolving a component A, a polymer derivative modified by an o-nitrobenzyl light trigger in a biocompatible medium to obtain a solution A, and dissolving a component B, an amino-containing polymer derivative or a double bond-containing polymer derivative or a fluorenyl-containing polymer derivative in the biocompatible medium to obtain a solution B; uniformly mixing the solution A, or adding the solution B thereto, to obtain a hydrogel precursor solution; irradiating the hydrogel precursor solution with a light source, such that the o-nitrobenzyl group in the component A simultaneously generates an aldehyde group/ketone group or a nitroso group under photoexcitation for double crosslinking, achieving a synergistic crosslinking effect. Further provided are a kit for the preparation of the hydrogel, as well as applications of the ...

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Номер записи: 5
02-06-2016 дата публикации

METHOD FOR PREPARING NON-FREE RADICAL PHOTOCHEMICAL CROSSLINKING HYDROGEL MATERIAL, AND PRODUCT AND APPLICATION THEREOF

Номер: WO2016082725A1
Автор: WANG, Yang, ZHU, Linyong, LIU, Zhenzhen, BAO, Chunyan, LIN, Qiuning, FANG, Wei
Принадлежит:

The present invention provides a method for preparing non-free radical photo-crosslinking hydrogel. The method comprises the following steps: dissolve a component A in a biocompatibility medium to obtain a solution A, and dissolve a component B such as a hydrazide, hydroxylamine or primary amine macromolecule derivative in the biocompatibility medium to obtain a solution B; uniformly mix the solution A and the solution B to obtain a hydrogel precursor solution; and when the hydrogel precursor solution is under illumination, an aldehyde group generated by o-nitrobenzyl in the component A in optical excitation and hydrazide, hydroxylamine or a primary amino group in the component B form hydrogel through cross-linking in a manner of respectively forming hydrazone, oxime, or a Schiff base. The present invention further provides a kit used for preparing hydrogel and applications of hydrogel in tissue repairing, beautifying, and serving as a cell, protein, or a drug carrier. According to the ...

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Номер записи: 6
04-04-2019 дата публикации

FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF

Номер: WO2019062876A1
Автор: ZHU, Linyong, YANG, Yi, BAO, Bingkun, ZHANG, Chenxia, ZHANG, Dasheng, BAO, Chunyan, LIN, Qiuning, LI, Ningfeng, HUA, Xin, ZHAO, Yongliang, LIU, Renmei, CHEN, Zhengda, SUN, Yuying
Принадлежит:

Provided are a fluorescent probe, a preparation method therefor and a use thereof. The fluorescent probe responds to viscosity sensitively and specifically, can be used for the specific fluorescence label of proteins, and can also be used in the quantification, detection or kinetic study of proteins and the imaging of cells, tissues and living bodies.

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Номер записи: 7
28-01-2004 дата публикации

离子型聚醚树枝体-线性聚丙烯酸两亲嵌段共聚物及其合成方法和用途

Номер: CN0001136245C
Автор: ZHU LINYONG, WANG ERJIAN, LI MIAOZHEN, LINYONG ZHU, ERJIAN WANG, MIAOZHEN LI, 朱麟勇
Принадлежит:

... 本发明属于两亲嵌段高分子化合物领域。它具有(I)、(II)、(III)的结构，其制法为先合成聚醚树枝体-线性聚丙烯酸甲酯嵌段共聚物；后通过PMA链上的酯基水解为羧基得到。此共聚物用于发光超分子络合物材料、药物缓释材料、流变性质调节剂等方面。它的活性比常规的两亲物高，临界缔合浓度比常规两亲物低。作为发光材料和稀土金属离子Tb#+[3+]络合物，其发光强度比单一的Tb#+[3+]离子的发光增强150多倍。∴或∴或∴ ...

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Номер записи: 8
25-01-2018 дата публикации

FLUORESCENT DYE AND PREPARATION METHOD AND USE THEREOF

Номер: WO2018014820A1
Автор: ZHU, Linyong, YANG, Yi, ZHANG, Dasheng, DU, Zengmin, BAO, Bingkun, LIN, Qiuning, LI, Yan, CHEN, Xianjun, YANG, Lipeng, BAO, Chunyan
Принадлежит:

Provided are a fluorescent dye and a preparation method and use thereof. The fluorescent dye has the ability to emit a long wavelength, is sensitive and specific to a viscosity response, can be used for a viscosity test, and can also be used as a fluorogenic probe for fluorescence labelling, quantification or detection of a protein, an enzyme or a nucleic acid.

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Номер записи: 9
23-06-2023 дата публикации

Polysaccharide-based macromolecular cross-linking agent, polysaccharide-based biological material, preparation method and application

Номер: CN116284492A
Автор: LIN QIUNING, CHEN TING, BAO BINGKUN, XIAO CHAONAN, ZHU LINYONG
Принадлежит:

The invention relates to a polysaccharide-based macromolecular cross-linking agent, a polysaccharide-based biological material, and a preparation method and application of the polysaccharide-based macromolecular cross-linking agent. The polysaccharide-based macromolecular cross-linking agent disclosed by the invention is an o-phthalaldehyde group modified polysaccharide-based macromolecular cross-linking agent, and the polysaccharide-based macromolecular cross-linking agent does not depend on an artificially synthesized hydrophilic macromolecular skeleton and complex chemical synthesis steps. The polysaccharide-based polymer cross-linking agent provided by the invention and water-soluble micromolecules or macromolecules containing one or more groups of primary amine, diamine, hydrazide, hydroxylamine or sulfydryl jointly form a polysaccharide-based two-component hydrogel material in an aqueous medium, and the polysaccharide-based two-component hydrogel material has the advantages of injectability ...

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Номер записи: 10
22-09-2004 дата публикации

石材保护剂及其制造方法

Номер: CN0001167756C
Автор: ZHU LINYONG, LIN XINXIN, LIN JIANWEI, LINYONG ZHU, XINXIN LIN, JIANWEI LIN, 朱麟勇
Принадлежит:

... 本发明为一种石材保护剂，包含有全氟高分子聚合物，其聚合物单体为单体I，含硅单体II，单体III及除I、II、III聚合物单体以外的烯基聚合物单体IV。其单体I、单体II、单体III重量百分比依次为聚合物单体总重量的40～90％，1～18％，2～50％。上述聚合物单体共同在引发剂存在下进行溶液聚合，引发剂用量为0.1～2％，采用的溶剂为酮、酯、醇溶剂的一种，该溶剂加入量为100～300％。全氟高分子石材保护剂有溶剂型或水溶型，经石材保护剂处理的不同石材，在不同的环境下匀具有良好的拒水、拒油效果。涂覆方法简单，制造条件温和，可适应大理石、花岗岩、砂岩、砖瓦、水泥、陶瓷或石膏等天然或人造石材。 ...

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Номер записи: 11
28-01-2004 дата публикации

离子型聚醚树枝体-线性聚丙烯酸两亲嵌段共聚物/稀土金属离子发光复合物及其制备方法

Номер: CN0001136268C
Автор: ZHU LINYONG, WANG ERJIAN, LI MIAOZHEN, LINYONG ZHU, ERJIAN WANG, MIAOZHEN LI, 朱麟勇
Принадлежит:

... 本发明属于稀土金属发光材料领域，它由离子型聚醚树枝体-线性聚丙烯酸两亲嵌段共聚物和稀土金属离子组成，两者的摩尔数比为5×10#+[-7]～5×10#+[-4]∶2×10#+[-5]～1.2×10#+[-3]。在常温下，按以上配比将镧系金属氯化物水溶液加入至离子型聚醚树枝体-线性聚丙烯酸两亲嵌段共聚物水溶液中，保持pH为7.5～9，静置12小时左右，便得离子型聚醚树枝体-线性聚丙烯酸两亲嵌段共聚物/稀土金属复合物。它具有很高的发光效率，能应用于光放大、显示、防伪、环境探针和传感元件。 ...

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Номер записи: 12