11-01-2018 дата публикации
Номер: US20180008948A1
The present invention relates to a method for preparing solid capsules comprising a compound A, dispersed in a composition C4. 1. A method for preparing solid capsules , comprising the following steps: C1 and C2 not being miscible with each other,', 'C2 being at temperature T2,', 'whereby an emulsion is obtained comprising drops of composition C1 dispersed in the composition C2,, 'a) adding with stirring a composition C1 comprising at least one compound A, in a liquid composition C2 comprising a thermo-expansible material,'} C3 and C2 not being miscible with each other,', 'C3 being at temperature T3, preferably equal to T2,', 'whereby an emulsion is obtained comprising drops dispersed in the composition C3,, 'b) addition with stirring of the emulsion obtained in step a) into a liquid composition C3 able to be polymerized,'} C4 and C3 not being miscible with each other,', 'C4 being at temperature T4 less than or equal to T2 and less than or equal to T3,', 'whereby an emulsion is obtained comprising drops dispersed in the composition C4, and, 'c) addition with stirring of the emulsion obtained in step b) in a liquid composition C4,'}d) polymerization of the drops obtained in step c),whereby solid capsules are obtained, dispersed in the composition C4.2. The method according to claim 1 , wherein the composition C1 is a solution comprising the compound A in a solubilized form.3. The method according to claim 1 , wherein the composition C1 is an emulsion formed with drops of a solution comprising the compound A in a solubilized form claim 1 , said drops being dispersed in a composition C′3 able to be polymerized.4. The method according to claim 1 , wherein after step b) and before step c) claim 1 , steps a) and b) are repeated at least once.5. The method according to claim 1 , wherein the thermo-expansible material is selected from the group consisting of waxes claim 1 , fluorocarbons claim 1 , and mixtures thereof.6. The method according to claim 1 , wherein the thermo- ...
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