ВВИНЧИВАЕМОЕ УСТРОЙСТВО ДЛЯ АНАСТОМОЗА

Изобретение относится к устройствам для анастомоза и может быть использовано для анастомоза боковой стороны одного сосуда к другому сосуду или конца одного сосуда к боковой стороне другого сосуда, такими как, например, кровеносные сосуды, кишки, мочеточники или трахея со стенками определенной толщины. Ввинчиваемое устройство включает винтообразную спиральную пружину с витками и нережущим перфорирующим приспособлением. Витки винтообразной спиральной пружины соединены между собой с заранее определенным минимальным расстоянием между ними. Минимальное расстояние между витками соответствует толщине стенок сосудов. Нережущее перфорирующее приспособление неподвижно прикреплено к винтообразной спиральной пружине или съемно прикреплено к винтообразной спиральной пружине. В результате устройство обеспечивает возможность присоединения боковых частей двух сосудов (бок-в-бок) или конца одного сосуда с боковой частью другого сосуда (конец-в-бок) без наложения швов. 3 н. и 12 з.п. ф-лы, 8 ил.

СПОСОБ ФОРМИРОВАНИЯ СИСТЕМНО-ЛЕГОЧНОГО АНАСТОМОЗА БЕЗ ВСКРЫТИЯ ПЕРИКАРДА (ЭКСТРАПЕРИКАРДИАЛЬНО)

Изобретение относится к медицине, а именно к кардиохирургии. Накладывают два шва-держалки на правую или левую боковую стенку восходящей аорты за адвентициальный слой и боковую стенку верхней полой вены в проекции восходящей аорты и верхней полой вены. Далее формируют «ложе» для протеза путем резекции парааортальных и паратрахеальных лимфатических узлов. Выполняют отслаивание перикарда от передней стенки правой или левой легочной артерии, выполняют ее мобилизацию от бифуркации до деления на долевые ветви. Накладывают сосудистый зажим проксимальнее к бифуркации ствола легочной артерии на правую или левую легочную артерию, при этом выделяют 2 см правой или левой легочной артерии с последующим формированием анастомоза между протезом ПТФЕ и правой или левой легочной артерией. Способ позволяет сохранить нативный аутоперикард в качестве пластического материала для последующих этапов оперативного лечения, а также предупреждает развитие спаечного процесса в переднем средостении, снижает риск осложнений ...

Способ реваскуляризации головного мозга при локальном гемодинамически значимом стенозе внутренней сонной артерии

Изобретение относится к области медицины, а именно сердечно-сосудистой хирургии. Для снижения риска формирования рестеноза ВСА после выполнения реваскуляризации головного мозга при локальном гемодинамически значимом стенозе ВСА в ее устье до ее отсечения пережимают ОСА, НСА и ВСА. НСА и ВСА пережимают на 4 см выше их устья. ВСА отсекают выше устья на 2,5 см. Участок ВСА с локальным стенозом в устье прошивают. В боковой стенке НСА на 2,5 см выше ее устья формируют округлое отверстие диаметром 0,5 см. Отсеченный участок ВСА имплантируют в сформированное отверстие в НСА при помощи формирования анастомоза «конец-в-бок». Способ исключает воспаление внутренней поверхности ВСА и снижает риск возникновения гиперплазии неоинтимы за счет исключения удаления атеросклеротической бляшки. 1 ил., 1 табл., 5 пр.

АНКЕРНОЕ ВВИНЧИВАЕМОЕ УСТРОЙСТВО

... 1. Хирургическое ввинчиваемое устройство, приспособленное к закреплению в стенке структуры трубочного типа внутри человеческого тела, такой как например кровеносный сосуд или мочеточник, включающее полый винт с витками, между которыми при применении закрепляется стенка структуры трубочного типа, отличающееся тем, что включает нережущее перфорирующее приспособление, которое может быть прикреплено постоянно или съемно к полому винту, которое предназначено для перфорирования стенки структуры трубочного типа таким образом, чтобы было возможным прохождение витков полого винта путем ввинчивания. 2. Хирургическое ввинчиваемое устройство по п.1, отличающееся тем, что устройство для перфорирования образовано передним витком полого винта, передний виток имеет острый и закругленный конец. 3. Хирургическое ввинчиваемое устройство по п.2, отличающееся тем, что острый и закругленный конец отогнут внутрь и вниз под углом от 10 до 20° по отношению к другим виткам. 4. Хирургическое ввинчиваемое устройство ...

Способ протезирования магистральных ветвей аорты

Изобретение относится к медицине, а именно к сердечно-сосудистой хирургии. После имплантации основного стента-графта в аорту выполняют аортографию и определяют место отхождения перекрытых магистральных ветвей аорты. Системой проводник-катетер выполняют перфорацию материала стента-графта. Заводят проводник в магистральную ветвь, баллонным катетером выполняют предилятацию стенки основного стента-графта. По проводнику заводят периферический стент-графт. При этом металлический каркас периферического стент-графта с сегментом для бесшовного соединения с основным стент-графтом выполнен длиной 2 см в виде единой плетёной конструкции из цельной проволоки конической формы с возможностью расширения и расположен внутри биосовместимого тканного материала. Биосовместимый тканный материал покрывает металлический каркас с сегментом для бесшовного соединения с основным стент-графтом и прикреплен на всем его протяжении, а сегмент для бесшовного соединения с основным стент-графтом в проксимальной части выполнен ...

ФИКСИРУЮЩЕ УСТРОЙСТВО

... 1. Фиксирующее устройство, связываемое с первым объектом для прикрепления указанного объекта ко второму объекту и содержащее, по меньшей мере, один фиксирующий элемент, имеющий базовую часть и, по меньшей мере, одну закрепляющую часть, при этом ! фиксирующий элемент первоначально формируется с закрепляющей частью, имеющей первую ориентацию относительно базовой части, и с возможностью придания закрепляющей части второй ориентации относительно базовой части для обеспечения возможности вхождения, по меньшей мере, одной закрепляющей части, при сохранении второй ориентации, во второй объект, открытый для такого вхождения, и способной изменять вторую ориентацию на первую ориентацию для осуществления указанного прикрепления. !2. Устройство по п.1, отличающееся тем, что, по меньшей мере, один фиксирующий элемент содержит удерживаемую часть, находящуюся между его базовой и закрепляющей частями, причем указанный фиксирующий элемент первоначально формируется с закрепляющей частью, имеющей первую ориентацию ...

ПРОТЕЗ ДЛЯ СОЕДИНЕНИЯ АНАТОМИЧЕСКОГО КАНАЛА

... 1. Трубчатый протез для соединения анатомического канала (С), который содержит, по меньшей мере, два отдельных трубчатых элемента (2) и механические средства (4) для соединения указанных отдельных элементов друг с другом,в котором механические соединительные средства являются герметичными (4) и содержат:- две имеющие кольцевую форму соединительные части (6), при этом каждая из них прикреплена к свободному концу (5L) отдельного трубчатого элемента (2);- по меньшей мере, одно уплотнение (8), имеющееся на одной из двух соединительных частей (6) и выполненное таким образом, чтобы вставляться между двумя соединительными частями (6) вокруг отверстия (3), образованного трубчатым протезом; и- первое и второе фиксирующее кольцо (9А, 9В), причем через каждое проходит отдельный трубчатый элемент (2) и каждое выполнено таким образом, чтобы взаимодействовать друг с другом для удерживания вместе, относительно одна другой, двух соединительных частей (6), между которыми сжимается уплотнение (8).2. Протез ...

СИСТЕМА И СПОСОБ ПОВЫШЕНИЯ НАРУЖНОГО ДИАМЕТРА ВЕН И АРТЕРИЙ

Multi-Ballon-Approximator zur Anastomisierung von Hohllumen

Wobei diese Approximationsvorrichtung gekennzeichnet ist durch einen Rohrkörper (9) mit einem ersten (10) und einem zweiten Ende (11) und sich zwischen diesen erstreckender Längsachse, innerhalb welchem sich mindestens ein coaxial zu dieser Längsachse verlaufendes Arbeitslumen (12) mit einem ersten (13) und einem zweiten Ende (14) erstreckt, welches ausreichend bemessen ist, mindestens ein Innenglied (27) mit einem ersten (28) und einem zweiten Ende (29) und einer sich zwischen diesen erstreckenden Längsachse in gleitender und frei rotierender Beziehung aufzunehmen, so dass dieses mindestens eine Innenglied (27) nach regelrechter Einbringung in das mindestens eine Rohrkörperarbeitslumen (12) mit seinem ersten Ende (28) dessen Eintrittsöffnung (13) und mit seinem zweiten Ende (29) dessen Austrittsöffnung (14) überragt.

VERBINDUNGSVORRICHTUNG ZWISCHEN EINEM KÖRPERKANAL UND EINER PROTHESE

LEITUNGSKUPPLUNGSVORRICHTUNG SOWIE GERÄTEZUSAMMENSTELLUNG ZUM BETRIEB EINER SOLCHEN VORRICHTUNG

Beschichtete endovaskuläre Vorrichtung

VORRICHTUNG ZUM ZEITWEILINGEN ABDICHTEN VON BLUTGEFÄSSEN BEI ANASTOMOSE

INSTRUMENT ZUR ANASTOMOSE

VORRICHTUNG ZUR ERLEICHTERUNG EINER TERMINOLATERALEN ANASTOMOSE-OPERATION

Chirurgisches Klammernahtgerät

VORRICHTUNG ZUM BEFESTIGEN EINES IMPLANTATS AN EINEM BLUTGEFÄSS

Chirurgisches Instrument

Um ein chirurgisches Instrument zum Verbinden von Körpergewebe mit einem Schaft und einem ersten und einem zweiten Werkzeugelement, welche Werkzeugelemente relativ zueinander bewegbar angeordnet oder ausgebildet sind und jeweils eine Elektrode umfassen, welche Elektroden in einer Annäherungsstellung der Werkzeugelemente einen minimalen Abstand voneinander definieren, einander gegenüberliegen und aufeinander zu weisen, wobei das erste Werkzeugelement am distalen Ende des Schafts angeordnet oder ausgebildet ist, so zu verbessern, dass eine mechanische Belastung von insbesondere mittels eines Stromflusses erzeugten Körpergewebeteilverbindungen beim Entfernen des chirurgischen Instruments minimiert wird, wird vorgeschlagen, dass das zweite Werkzeugelement von einer Betriebsstellung, in welcher es in die Annäherungsstellung bringbar ist, in eine Entfernungsstellung bringbar ist, in welcher Entfernungsstellung eine von der Elektrode des zweiten Werkzeugelements definierte Rückzugsumfangslinie ...

Apparatus for use in coronary artery bypass surgery

The apparatus comprises a blood flow conduit 10 of T- or L-shape having a first end for insertion into and retention within a wall of a heart chamber 44 containing oxygenated blood and a second end for retention within a coronary artery 30, the conduit defining an open flow blood path during both systole and diastole. The conduit may be such as to bias forward flow of blood from the first towards the second end while not blocking reverse flow and may comprise a deflection surface for blocking flow through the conduit from impinging directly upon the coronary artery. Means may be provided in the conduit for reducing but not blocking blood flow during diastole.

MEANS OF MOUNTING FOR CONNECTING A TUBULAR BLOOD VESSEL PROSTHESIS

TUBING CLAMP FOR THE ATTITUDE OF AN ANASTOMOSIS

DEVICE FOR THE ATTACHMENT OF A CONTAINER ANASTOMOSIS

VORRICHTUNG ZUR HERSTELLUNG VON ANASTOMOSEN ZWISCHEN HOHLORGANEN

RAPAMYCIN CONTAINING MEDICAL DEVICES

CONTAINER CATCH DEVICES

ADJUSTMENT DEVICE FOR FABRICS

SMOOTH ANASTOMOSIS DEVICE

A SETTER FOR A SURGICAL DEVICE

DEVICE FOR THE ATTACHMENT OF CONTAINER ANASTOMOSES

VORRICHTUNG ZUR HERSTELLUNG VON ANASTOMOSEN ZWISCHEN HOHLORGANEN

PROBE COUPLING ARRANGEMENT

DEVICE SYSTEM TO THE SEAM ANCHORAGE AS WELL AS ATTACHMENT DEVICE FOR IT

BISTABILE STRUCTURE OF FEATHER/SPRING FOR A STENT

DEVICE FOR THE EXECUTION OF AN ANASTOMOSIS

DEVICE FOR BRINGING IN A MEDICAL TRANSPLANT

DEVICE FOR FASTENING AN IMPLANT TO A BLOOD VESSEL

SYSTEM F�R INTERSTITIAL ONE TRANSVASKUL�RE SURGICAL INTERFERENCES

TRANSPLANT CATHETER F�R OF VASKULARES ENTRANCE SYSTEM

MEDICAL TRANSPLANT LINKS

Devices for performing vascular anastomoses

DEVICES AND METHODS FOR FISTULA FORMATION

Abstract: A device for forming a fistula between two vessels comprising a handle; a first arm fixedly connected to the handle; and a second arm adjustably connected to the handle, wherein at least one of the first arm and the second arm comprises a fistula forming element.

Graft anchor devices, systems and methods

The present disclosure provides medical devices, systems and methods and in particular to devices and methods useful for anchoring graft materials to bodily structures.

Graft-catheter vascular access system

Device and method for establishing an artificial arterio-venous fistula

DEVICES AND METHODS FOR FORMING MAGNETIC ANASTOMOSES BETWEEN VESSELS

Surgical stabilizer devices and methods

A device, system and method for interstitial transvascular intervention

Singleshot anastomosis instrument with detachable loading unit and method

Method and apparatus for performing an anastamosis

Anastomosis devices

Implantable medical devices (800) for connecting tissue layers or to circumvent occluded body conduits and tissue structures. The implantable medical devices include apposition portions (802, 804), a central region (806), and a covering material (812). The methods of using the devices include endoscopic deployment, and the devices may include self-expanding frameworks that facilitate a secure connection between the tissue structures. In some embodiments, one or more tethers (810 a, b, c) are used to longitudinally contract the device in ...

Anastomosis sheath and method of use

Intravascular arterial to venous anastomosis and tissue welding catheter

A catheter-based device tracks over a guidewire which has been placed from a first blood vessel into a second blood vessel. The distal tip of the catheter is advanced into the second vessel while a proximal member remains in the first vessel. Matching blunt tapered surfaces on each of the distal tip and the proximal member are clamped together, with adjacent walls of each vessel between them, after which a known, controlled pressure is applied between the two surfaces. Heat energy is then applied to the blunt surfaces for approximately 1-30 seconds to weld the wal ls of the two vessels together. After coaptation of the vessel walls, the heat is increased to then cut through the vessel walls to create a fistula of the desired size.

Catheters and related devices for forming passageways between blood vessels or other anatomical structures

Methods and apparatus for bypassing arterial obstructions and/or performing other transvascular procedures

Systems and methods for delivering drugs to selected locations within the body

A by-pass graft

Method and anastomotic instrument for use when performing an end-to-side anastomosis

Devices, systems and methods for creating sutureless on-demand vascular anastomoses and hollow organ communication channels

Sutureless anastomotic technique using a bioadhesive and device therefor

Medical grafting methods and apparatus

Tubular body structure marking methods and apparatus

Artificial tubular body organ grafts

GRAFT-CATHETER VASCULAR ACCESS SYSTEM

A vascular access device, for implantation at least partially below the skin of a patient to provide an arteriovenous fistula, includes a graft portion coupled to a catheter portion. The graft portion is sutured to an opening in an artery while the catheter portion is inserted into a vein so that its end lies within the vein downstream from the point of entry into the vein. The device may be comprised of ePTFE with an outer polyurethane coating or the graft portion may comprise ePTFE with an outer polyurethane coating and the catheter portion may comprise polyurethane. There may also be an inner polyurethane coating. Alternatively, the device may be comprised entirely of polyurethane.

SUTURING MEANS FOR CONNECTING A TUBULAR VASCULAR PROSTHESIS TO A BLOOD VESSEL IN THE BODY IN ADDITION TO BRANCH MEANS, A VASCULAR PROSTHESIS, A DEVICE FOR INSERTING AND SUTURING AVASCULAR PROSTHESIS IN THE BODY, AND A VASCULAR PROSTHESIS SYSTEM

Suturing means and branch means, a vascular prosthesis, a device and a vascular prosthesis system. Suturing means for connecting a vascular prosthesis (40) to a blood vessel (50) comprise an internal, substantially annular body (10) intended to be received in the blood vessel (50) in addition to an external annular body (20) intended to lie clampingly on an outer wall of the blood vessel (50) at least practically at the location of the internal annular body (10). At least one of the two annular bodies (10, 20) is provided with suturing members (12) which grip in the vessel wall so as to effect an adequate fixation of at least the internal annular body (10). The invention also provides a device for use with such suturing means and further relates to a vascular prosthesis which is provided on at least one of its outer ends with at least a part of such suturing means. Different embodiments of such prostheses together form a modular vascular prosthesis system. A side vessel of thus supported ...

STENT

An elongate device (19), arcuate in cross-section, for placement around a vessel (4), comprises an essentially non-porous outer layer and a biodegradable inner layer. An alternative device comprises a tubular portion (3) for placement around a graft and a portion (2), arcuate in cross-section that can straddle a native vessel, at the site of an end- to-side anastomosis.

DEVICES, SYSTEMS, AND METHODS FOR CREATION OF A PERIPHERALLY LOCATED FISTULA

... ²²²Devices, systems and methods are disclosed for the formation of an ²arteriovenous fistula in the limb of the patient. Embodiments include a device ²(10) for the creation, modification and maintenance of a fistula that includes ²an integral fistula creation assembly (25) near its distal end that passes ²through the skin of the patient, through a first vessel such as an artery, and ²into a second vessel such as a vein. The fistula creation assembly (25) ²preferably includes an anastomotic implant (60) that is placed within the ²fistula t maintain long term blood flow there through. The devices, systems ²and methods can be used to treat patients with one or more numerous ailments ²including chronic obstructive pulmonary disease, congestive heart failure, ²hypertension, hypotension, respirator failure, pulmonary arterial ²hypertension, lung fibrosis and adult respiratory distress syndrome.² ...

TISSUE APPROXIMATION DEVICE AND A METHOD OF USING IT

A tissue approximation device and processes for using the device are provided. The device is an implantable, biodegradable construct (except for hernia repairs) that has attachment points emanating from a supportive backing. The device improves the mechanical phase of wound healing and evenly distributes tension over the contact area between the device and tissue. Processes for using the device include wound closure, vascular anastomoses, soft tissue attachment and soft tissue to bone attachment. Several variations are particularly applicable to facilitating tissue approximation in surgical cosmetic applications including, for example, orbital rim reconstruction and tissue suspension.

AN ENDOLUMINAL SURGICAL DELIVERY SYSTEM

... ²²²A system (1) for delivering a staple (9) to the locus of an artery (2) ²comprises a delivery conduit (5) for inserting into the lumen of an artery ²through which conduit a staple can be delivered to the focus, and an elongate ²element (6) such as a catheter for a balloon (7) for translating axial ²advancement of the delivery conduit through the artery into movement of the ²distal end of the delivery conduit away from the longitudinal axis of the ²artery and towards the artery wall.² ...

PROBE COUPLER ASSEMBLY

An assembly for joining two vessel segments of a patient comprises a coupler formed of adjoining coupler halves, and a cuff. Each coupler half includes an aperture for receiving an end of one of the vessel segments. One coupler half comprises a connector element sized and shaped for connection to the other coupler half. The vessel segments are alignable in the respective coupler halves such that a path for fluid flow is formed therebetween upon connection of the coupler halves. A large diameter portion of the cuff is positioned over at least a portion of the coupler, and a small diameter portion of the cuff is positioned over one of the vessel segments. The cuff further includes a probe positioned at the small diameter portion. The probe is positioned within the cuff in a manner such that a signal is receivable therein corresponding to fluid flow through the vessel segment.

DEVICE AND METHOD FOR ESTABLISHING AN ARTIFICIAL ARTERIO-VENOUS FISTULA

A shunt rivet for implantation between a first body space and a second body space in a patient, such as to treat chronic obstructive pulmonary disease.

DEVICE FOR RAPID REPAIR OF BODY CONDUITS

A self-expanding stent-graft provided in a diametrically compacted state for implantation and retained preferably by a constraining sheath, useful for the temporary or permanent repair of injured, partially or entirely transected body conduits including blood vessels. It may be used under direct visualization to quickly stop or substantially reduce loss of blood from such damaged vessels and to quickly re-establish perfusion distal to the injury site. The device would typically be implanted under emergency room conditions but also be used in field situations by trained medical technicians. After an end of the device is inserted into a blood vessel through the injury access, deployment preferably initiates from the device end in a direction moving toward the middle of the length of the device by directionally releasing the constraining sheath. In a preferred embodiment, the two opposing ends of the device are individually deployable from the compacted, small diameter intended for insertion ...

ANASTOMOSIS DEVICE AND METHOD OF USING THE SAME

The present invention provides an anastomosis device which includes an elongate center pin having proximal and distal ends. The proximal end is configured to be graspable using a grasping tool. A grip mechanism is located at the distal end for crimping a suture. The device includes an outer sleeve having a passageway therethrough to receive therein the elongate center pin. A suture having a suture needle is attached to a first end of the center pin and a second end of the suture is formed into a pre-formed knot mounted on the sleeve. The device includes a suture release mechanism having a passageway extending therethrough to receive the outer sleeve therein. The suture release mechanism slides along the sleeve between a first position in which the suture release mechanism is spaced from the distal end and a second position such that movement of the suture release mechanism from the first position to the second position dislodges the pre-formed knot off the sleeve. A free end of the suture ...

STAPLING APPARATUS FOR PERFORMING ANASTOMOSIS ON HOLLOW ORGANS

A stapling apparatus for performing anastomosis on hollow organs consists of two combinable L-shaped tools, a clip retaining tool and a staple retaining tool. Each tool is provided with an elongated handle and a C-shaped jaw. In combined configuration the C-shaped jaw of the clip retaining tool is positioned below the C-shaped jaw of the staple retaining tool with the respective staples in registration with respective underlying clips. The C-shaped jaws provide gaps which permit ingress and egress of hollow organ ends. A staple firing mechanism is operated from the proximal top end of one of the handles of the apparatus whereby downward pressure is applied uniformly and simultaneously against the top of all staples to force them from their retaining sockets, through the hollow organ ends, and into stapling engagement with the respective underlying staple retaining clips.

SURGICAL RETRACTOR HAVING IMPROVED BLADES AND METHODS RELATED THERETO

The present invention relates to surgical retractors having improved blades for use on the retractor and devices for stabilizing a predetermined area for the body during a surgical procedure, more particularly to surgical retractors and stabilizing devices used in connection with minimally invasive coronary artery bypass grafting surgical procedures, and more specifically to surgical retractors and stabilizing devices especially configured for use with each other for such surgical procedures wherein the retractor (102) includes a plurality of grooves (132) on the bottom surface thereof and a plurality of blades (130) having a member (134) that is releasably received in the grooves (132) and which also allows for the pivotal movement of the blades (130) relative to the arms (113, 116) of the retractor (102) and further including nesting blades having a third section (134) which is generally linear and second sections which are preferably curved about 180 degrees to allow for the simplified ...

AN ENDOLUMINAL SURGICAL DELIVERY SYSTEM

A system (1) for delivering a staple (9) to the locus of an artery (2) comprises a delivery conduit (5) for inserting into the lumen of an artery through which conduit a staple can be delivered to the focus, and an elongate element (6) such as a catheter for a balloon (7) for translating axial advancement of the delivery conduit through the artery into movement of the distal end of the delivery conduit away from the longitudinal axis of the artery and towards the artery wall.

DRUG RELEASING ANASTOMOSIS DEVICES AND METHODS FOR TREATING ANASTOMOTIC SITES

Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.

A METHOD FOR INTERCONNECTING HOLLOW BODIES

An apparatus constructed from a super elastic material and having magnetic properties is provided for joining together at least two hollow bodies. The apparatus comprises a frame having at least one magnet mounted to an end thereof. The frame is substantially tubular and is preferably constructed from super elastic materials allowing the frame to assume a first expanded diameter and a second smaller diameter corresponding to the outer wall of a hollow body. The frame can be a wire helix that allows for radial and longitudinal flexing. Frames are disposed over the outer walls of the severed ends of at least two hollow bodies to be joined together. The hollow bodies are placed into contact such that the magnetic forces between the two frames links the two bodies together in tight fluid communication. A system for joining together two hollow bodies is provided. The system includes a magnetic frame that is placed around a severed end of a hollow body. A positioning member is located and fixed ...

MAGNETIC FRAME FOR CONNECTING HOLLOW BODIES

An apparatus constructed from a super elastic material and having magnetic properties is provided for joining together at least two hollow bodies. The apparatus comprises a frame having at least one magnet mounted to an end thereof. The frame is substantially tubular and is preferably constructed from super elastic materials allowing the frame to assume a first expanded diameter and a second smaller diameter corresponding to the outer wall of a hollow body. The frame can be a wire helix that allows for radial and longitudinal flexing. Frames are disposed over the outer walls of the severed ends of at least two hollow bodes to be joined together. The hollow bodies are placed into contact such that the magnetic forces between the two frames links the two bodies together in tight fluid communication.

DEVICE AND METHOD FOR ATRAUMATIC AND PERCUTANEOUS FORMATION OF AN ARTERIOVENOUS FISTULA

Provided herein are novel devices for the formation of arteriovenous fistulas, which may aid subjects in need of hemodialysis. The novel devices are provided in a non-surgical procedure, greatly decreasing the cost and increasing the convenience of placing an arteriovenous fistula. The devices are atraumatic, and consist of a sutureless anastomosis device and conduit. Methods and tools for placing the devices in vivo are disclosed, including a magnetic-assisted method.

VASCULAR GRAFT PROTECTOR

A vascular graft protector configured for removal from ingrown tissue comprising an axial spine from which emanate a plurality of semi-circular circumferential rib sets having ends separated by a circumferential gap and wherein each rib set is separated by an axial gap.

CONNECTOR FOR COUPLING ANATOMICAL WALLS

The present invention relates to a connector for fluid communication between two anatomical compartments through at least one anatomical wall, wherein the connector comprises a neck adapted and configured to be positioned across the anatomical wall(s); primary means for securing the neck across the anatomical wall(s); and secondary means for securing the neck across the anatomical wall(s). The invention also relates to a method for coupling two anatomical walls using said connector.

ANASTOMOSIS DEVICES

DEVICES AND METHODS FOR FORMING MAGNETIC ANASTOMOSES AND PORTS IN VESSELS

Methods and devices for forming magnetic anastomoses between hollow bodies. End-to-side, side-to-side and end-to-end anastomoses can be created with or without a mechanical connection between the components. The anastomotic components (542) may have various constructions and may be secured to a vessel in various manners, for example, magnetically, mechanically or adhesively. Also provided are alternative delivery devices (550), as well as devices (770, 730) for checking the position of a component on a loaded delivery device (772), and for checking the seal between a vessel and an anastomotic component (774, 776) secured thereto.

SLED ASSEMBLY FOR USE WITH A SURGICAL RETRACTOR AND MEDICAL INSTRUMENT

... ▓▓▓The present invention relates to an improved sled assembly for use with ▓surgical retractors and devices for stabilizing a predetermined area of the ▓body during a surgical procedure, more particularly to surgical retractors and ▓stabilizing devices used in connection with coronary artery bypass grafting ▓surgical procedures, and more specifically to a sled assembly having a sled ▓member and mounting mechanism thereon for use with surgical retractors and ▓medical or stabilizing devices especially configured for use with each other ▓for such surgical procedures wherein the retractor includes an external rail ▓system which enables the surgeon to position a stabilization arm system on ▓either of the arms or the rack segment of the retractor and also includes a ▓sled assembly which releasably controls the rotation of the stabilizing device ▓in a three dimensional directions relative to the retractor upon actuation of ▓a single knob or actuator.▓ ...

PROSTHESIS FIXATION DEVICE AND METHOD

APPARATUS AND METHOD FOR FORMING A HOLE IN A HOLLOW ORGAN

APPARATUS FOR DELIVERING SHAPE MEMORY ALLOY STAPLES

An apparatus including a plurality of chambers for receiving an associated plurality of staples, each formed with a shape memory that allows the staple to adopt a straightened configuration, when placed in a stapler, and a deployed configuration for suturing when released from the stapler.

INTRAVASCULAR ARTERIAL TO VENOUS ANASTOMOSIS AND TISSUE WELDING CATHETER

A device for creating an arteriovenous (AV) fistula comprises an elongate member, a distal member connected to the elongate member and movable relative to the elongate member, and a heating member disposed on at least one of the movable distal member and the elongate member. The distal member comprises structure for capturing tissue to be cut to create the fistula, and the heating member is adapted to cut through the tissue to create the fistula. The elongate member comprises an elongate outer tube. A shaft connects the distal member to the elongate member, and is extendable and retractable to extend and retract the distal member relative to the elongate member.

DEVICES AND METHODS FOR OCCLUDING OR PROMOTING FLUID FLOW

Devices and methods for occluding or promoting fluid flow through openings are disclosed. In one exemplary embodiment an occlusion device (10) is provided having an expandable outer elongate tubular body (20), a guide member (30) extending from a distal end (20d) of the outer body, and a slide tube (40) disposed within the outer body, the proximal portions (20p,40p) of the outer body and the slide tube being fixedly mated. The slide tube is configured to slide distally within the outer tubular body when the tubular body is expanded to form wings (24a, 24b). A tether (60) can be included as part of the device and it can be used to assist in positioning and locking a location of the device in an opening. Exemplary methods for delivering devices disclosed herein are also provided.

SYSTEMS AND METHODS FOR PERCUTANEOUS INTRAVASCULAR ACCESS AND GUIDEWIRE PLACEMENT

A device for allowing passage of a guidewire from a primary blood vessel to an adjacent secondary blood vessel includes a main body having a primary lumen and a secondary lumen, and a piercing member disposed in the secondary lumen, and configured to be moved distally out of the secondary lumen, and to pierce through tissue while being distally moved. A third lumen located within the piercing member is configured to allow placement of a guidewire from the primary blood vessel to the adjacent secondary blood vessel. In one embodiment, the secondary lumen is configured to allow articulation of the distal end of the piercing element. The piercing member has a sharp point on one end to facilitate cutting a small communicating aperture from the primary blood vessel to the secondary blood vessel.

COUNTERPULSATION DEVICE DRIVER APPARATUS, METHOD AND SYSTEM

A method of operating a counterpulsation device (CPD) in a human or animal subject is disclosed, the method including: receiving a heart beat signal indicative of the heart beat of the subject; providing counterpulsation therapy by controlling the pressure supplied to a CPD drive line in pneumatic communication with the CPD to cause the CPD to alternately fill with blood and eject blood with a timing that is determined at least in part based on the heart beat signal; while providing counterpulsation therapy, receiving a CPD drive line pressure signal indicative of the pressure in the CPD drive line; and adjusting the pressure supplied to the drive line based at least in part on the drive line pressure signal.

ULTRASOUND-DETECTABLE MARKERS, ULTRASOUND SYSTEM, AND METHODS FOR MONITORING VASCULAR FLOW AND PATENCY

An ultrasound-detectable marker, ultrasound system, and methods for monitoring vascular flow and patency are disclosed. The ultrasound-detectable marker comprises one or more resorbable polymers, one or more non-resorbable polymers, one or more non-polymeric materials, or any combinations thereof. The ultrasound-detectable marker is adapted for placement underneath, adjacent to, or above one or more vessels at a postoperative site, such as a vascular anastomosis site. Further, the ultrasound imaging system includes certain user guiding software and/or health analysis software for use with the ultrasound-detectable marker.

METHOD AND ANASTOMOTIC INSTRUMENT FOR USE WHEN PERFORMING ANEND-TO-SIDE ANASTOMOSIS

When performing an end-to-side anastomosis connecting the end (10) of a firs t vessel (9) to the edge region (12) around an opening in the side wall of a second vessel (11), an instrument (1) is used having a circumferential stapling anvil (3) secured to an anvil tube (2) accommodating the first vess el (9), the end of which is everted about the anvil (3) with the intima of the end region (10) facing the intima of the edge region (12), when the instrume nt (1) with the first vessel (9) in place has been inserted into the opening in the second vessel (11). Then, a clamping tube (5) is advanced towards the anvil (3), clamping the end (10) and edge region (12) together against the anvil (3). In the next step, a number of stapling plungers (6) carrying staples (7) are advanced towards the anvil (3), the latter having staple- bending surfaces (4), thus stapling the two vessels together in a manner not shown. Finally, the clamping tube (5) and the stapling plungers (6) are withdrawn, and the ...

ANASTOMOSIS INSTRUMENT AND METHOD

A surgical instrument for performing an anastomosis includes a housing having a proximal end and a distal end; a shaft extending from the housing distal end; and a disposable loading unit configured and dimensioned to retain a plurality of surgical fasteners, the disposable loading unit extending from the shaft and forming a juncture with the shaft, the disposable loading unit including: i) opposed split-sections pivotably connected to facilitate movement of the opposed split-sections between open and closed configurations, the opposed split sections being movable through a firing stroke from a first position to a second position and back to the first position to form a plurality of surgical fasteners; and ii) a pivot lockout member including a latch portion which extends between the opposed splitsections, the latch portion including a contact surface which interacts with a corresponding surface formed on at least one of the opposed split-sections to retain the opposed split-sections in ...

TRANSABDOMINAL DEVICE FOR PERFORMING CLOSED-CHEST CARDIAC SURGERY

Surgical apparatus and devices are provided for performing closed chest cardiac surgery. A multi-lumen substantially tubular channel is inserted transabdominally to gain access to either the pleural or mediastinal space for the purposes of achieving less invasive cardiac surgery, more particularly complete revascularization CABG surgery directly on the beating heart. The said channel includes provisions for setting heart positioning and orienting devices, coronary artery stabilization devices, cannulae, catheters and sensors. The channel also has a provision such as designated multiple lumens and compliant seals for the introduction and preservation of pressurized gases within the accessed cavity. The principles and design features can be utilized in beating heart bypass surgery, valvular surgery, and general cardiac repair surgery by providing a means of introducing desired materials, surgical instruments, instrumentation into the accessed cavities.

ENDOLUMENAL AORTIC ISOLATION ASSEMBLY AND METHOD

A medical device assembly is adapted to isolate the heart from systemic circulation while perfusing oxygenated blood to the systemic arterial circulation during a minimally invasive bypass procedure. The assembly includes a catheter with an external shunt valve (3) which forms an anchor to secure the distal end portion within the aortic arch, and forms a funnel which shunts ante-grade blood flow from the aortic root, into a distal flow port (4), through a flow lumen in the catheter (1), out an intermediate flow port (5) along the catheter (1) proximally of the anchor, and into the systemic arterial circulation. A distal internal valve (6) within the lumen between the distal, the intermediate flow ports selectively occludes the shunted antegrade aortic blood flow between the distal flow port (4), the intermediate flow port (5), thereby isolating the left ventricle from the systemic arterial circulation wherein oxygenated blood may then flow.

Device for the execution of an anastomosis.

Device for the operational connection of hollow organs, in particular of blood vessels.

Die Vorrichtung (20) für das Verbinden von Hohlorganen (24, 25) umfasst verschiedene Elemente, die von Haltevorrichtungen gehalten werden. Diese sind auf einer Schiene (21) lateral verschiebbar, drehbar oder abnehm- und aufsteckbar und bei Bedarf in ihrer Lage fixierbar. Die Traverse (31) dient als Anschlag für die axiale Ausrichtung der Haltevorrichtungen. Die beiden Haltevorrichtungen (22, 23) tragen Klemmvorrichtungen für das Festhalten und eventuell Abklemmen der Hohlorganstümpfe (24, 25). Die Haltevorrichtungen (26, 27) tragen Hülsen (10, 11). Die beiden zu verbindenden Hohlorganstümpfe (24, 25) werden so durch sie hindurchgeschoben, dass sie um ein vorbestimmtes Mass über die Hülsenenden hinausragen. Anschliessend werden die Enden der Hohlorgane mittels zweier Umstülpvorrichtungen (28, 29) um die Enden dieser Hülsen umgestülpt. Die Haltevorrichtung (30) in der Mitte hält ein Fitting (14), in das die beiden erwähnten Hülsen (10, 11) mit den umgestülpten Hohlorganstümpfen eingeschoben ...

Device i.e. crimper, for forming surgical suture and micro-anastomosis of blood vessels of patient, has case containing single mechanism actuated by action of single finger and single hand of operator or by similar action of remote control

The device has a case containing a single mechanism in parts formed of cylindrical handle (1) and curved neck (2) causing distribution, presentation and setting of clips. Levers (7, 7a) are accessible from outside of the case. A removable, interchangeable hopper contains the clips. The mechanism is actuated to initially cause the setting of the clip by bringing the levers together, fast D-spacing of the levers in time, releasing the clip and allowing shrinking of crimper. An internal mechanism automatically positions the clips successively one after another inside the mechanism. The actuation of the single mechanism is obtained by action of single finger and a single hand of the operator or by similar action of remote control.

Biological tissue connection and repair devices and methods of using same

The instant invention provides compositions and methods for promoting the repair and/or growth of biological tissue, e.g., tubular biological tissue such as nerves. Specifically, the instant invention provides tissue connection devices and tissue repair devices and methods for using these devices.

Applicators for patches and adhesives

Apparatus is provided for use with a tubular structure ( 2 ) in a body of a patient. The apparatus includes an adhesive including first and second components, a container ( 27 ), one or more patches ( 3 ), and an applicator ( 1 ). The container ( 27 ) contains the first component of the adhesive and not the second component of the adhesive. The one or more patches ( 3 ) include the second component of the adhesive and not the first component of the adhesive. The applicator ( 1 ) is configured to removably hold the one or more patches ( 3 ), and to place the one or more patches ( 3 ) at least partially around the tubular structure ( 2 ). Other embodiments are also described.

Stent Graft System

The stent graft system in accordance with the present invention has a trunk, a left subclavian tube, a left common carotid tube and a brachiocephalic tube. The trunk is tubular and expandable and has a descending end, an ascending end, a left subclavian mount, a left common carotid mount and a brachiocephalic mount, for receiving the aforementioned branch tubes that are elastic and self-expandable for respectively connecting the left subclavian artery, the left common carotid artery and the brachiocephalic artery to the trunk. With the above-described structure, the present invention allows fast determination of a suitable trunk and branch tubes for a patient and allows a medical institute to prepare compatible branch tubes and trunks for a composite stent graft system instead of numerous stent grafts of various combinations of differently sized tubular bodies and branches, wherein the former requires significantly less warehousing cost than the latter.

Device and method for performing multiple anastomoses

Methods and devices for creating a seal in a vessel for performing multiple anastomoses. The device includes an expandable region at the shaft assembly distal end with a sealing membrane that spans the expandable region, and a corresponding clamping member moveable toward the expandable region. Once inserted into the vessel lumen the expandable region is deployed from a first low-profile position into a second expanded position, and positioned at the target site of the anastomoses. Movement of the distal end of the clamping member, which remains located outside the vessel, against the expanded region creates a seal at the target site allowing a blood-free, graft site area that is large enough to accommodate multiples anastomoses.

Probe coupler assembly

An assembly for joining two vessel segments of a patient includes a coupler formed of adjoining coupler halves. Each coupler half includes an aperture for receiving an end of one of the vessel segments. One of the coupler halves includes a connector element configured for connection to the other coupler half. The vessel segments are alignable in the respective coupler halves such that a path for fluid flow is formed therebetween upon connection of the coupler halves. A probe is aligned in engagement with a coupler half for generating a signal corresponding to fluid flow through the path.

Graft Devices and Methods of Use

A tubular graft device is provided comprising a tubular member and a fiber matrix of one or more polymers about a circumference of the tubular member. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a harvested saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft and connecting the graft between a first body space and a second body space, such as the aorta and a location on an occluded coronary artery, distal to the occlusion.

Intra-atrial implants made of non-braided material

Several unique intra-cardiac pressure devices, placement catheters, methods of placement and methods of treating heart failure are presented. The intra-cardiac pressure devices presented allow sufficient flow from the left atrium to the right atrium to enable the relief of elevated left atrial pressure and resulting patient symptoms. The intra-cardiac pressure devices are made of a non-braided material.

Vascular Shield and Delivery System

Devices for providing physical support to vascular regions including vascular regions that may contain an anastomosis region are disclosed. These devices may also deliver therapeutic agents to the vascular region. Methods for using these devices are disclosed, as well.

Surgical Stapling System

A system is provided for joining two tubular structures by a surgical stapling procedure. The system includes a series of sizers, a specifically designed graft, a loading unit, a wand, a tourniquet, and a stapling instrument. As a result, a plurality of staples may be simultaneously deployed quickly and accurately in a circumferential pattern so as to join together two tubular structures. The system may be used in either an open surgical procedure or laparascopically.

Vascular Clamps for Vascular Repair

A magnetic vascular clamp for vascular repair is described. There is a vascular sleeve forming a flexible cylindrical bellows that cylindrically encloses a section of vascular tissue to allow freely movement of the enclosed vascular tissue within the vascular sleeve. A pair of sleeve anchor rings are at each end of the vascular sleeve and they form a fixed seal with underlying vascular tissue to minimize fluid leakage from within the vascular clamp.

Anastomosis system and method

A system for performing anastomosis includes a plurality of staples, an annular staple support having structure for holding the staples, and a staple closing device for closing the staples to secure the canal ends together. A method for performing anastomosis and staples for performing anastomosis are also disclosed.

Assembly comprising a ring for attachment in a passage surrounded by body tissue as well as an applicator for fitting the ring in the passage

The present invention relates to an assembly comprising: a ring having anchoring elements for attaching the ring in a passage surrounded by body tissue, in particular blood vessel tissue. an applicator for fitting the ring in the passage; in which the anchoring elements have an anchoring position in which they protrude with respect to the ring, and in which the anchoring elements comprise a memory material, such as a memory metal or memory polymer, and are designed so that they can be bent from an anchoring position counter to a spring force into a fitting position and can be frozen in this fitting position by a temperature treatment in order to bend the anchoring elements back from the fitting position by the effect of this spring force into the anchoring position when a predetermined threshold temperature is exceeded, and in which the applicator is provided distally with a carrier for carrying the ring. The assembly according to the invention is provided with an influencing system for influencing the temperature of the anchoring elements of the ring carried by the carrier in such a way that the anchoring elements bend back from the fitting position to the anchoring position by increasing the temperature of the anchoring elements to above the threshold temperature.

Arteriovenous Shunt Having a Flow Control Mechanism

An arteriovenous shunt assembly including a shunt and a pull wire operated flow control mechanism. The shunt has a tubular body that defines a fluid passageway between a first end and a second end thereof The pull wire mechanism includes a portion disposed around the tubular shunt in at least one loop. The at least one loop may be selectively tightened or loosened remotely from the shunt to regulate the rate of blood flow through the tubular shunt.

Systems, devices, and methods for organ retroperfusion along with regional mild hypothermia

Systems, devices, and methods for organ retroperfusion along with regional mild hypothermia. In at least one embodiment of a method of organ perfusion of the present disclosure, the method comprises the steps of positioning at least part of a first catheter having a cannula within an artery of a patient, the first catheter configured to permit arterial blood to flow therethrough and further configured to permit a portion of the arterial blood to flow through the cannula, positioning at least part of a second catheter within a vein of the patient at or near a target organ, the second catheter configured to receive some or all of the portion of the arterial blood, connecting the cannula of the first catheter to a portion of the second catheter so that some or all of the portion of the arterial blood flowing through the cannula is provided into the vein to treat a condition or disease of the target organ, and reducing and/or regulating a temperature of blood flowing through the cannula using a regional hypothermia system operably coupled to the cannula.

Prosthesis for connecting an anatomical duct

According to the invention, the tubular prosthesis for connecting an anatomical duct includes at least two individual tubular elements and a sealed mechanical element for connecting said separate elements to each other.

Preform produced by electrospinning, method for producing the same and use of such a preform

The invention relates to a method for producing a preform by means of an electrospinning process. The present invention also relates to the use of the present preform as a substrate for growing human or animal tissue thereon. The present invention furthermore relates to a method for growing human or animal tissue on a substrate, wherein the present preform is used as the substrate.

Methods of securing a fastener

Embodiments may include an attachable fastener, which may include a bondable material that may be secured to the end of an end effector. Vibration may be tuned to occur at a distal end of the fastener. Accordingly, the fastener may be used to generate heat at a distal point of contact. If the contact surface contains bondable material, that material may be softened. If the fastener includes bondable material at the point of contact, that material may also be softened by heat produced by vibration at the contact area. A hard implant or another polymeric material may function as the anvil.

Open surgery anastomosis device, system, and method

A medical device, system and method tor an open surgical procedure configured to couple, for example, open ends of anatomical structures. The system includes an expandable tubular structure and inflatable balloon positioned within the tubular structure. The tubular structure includes a lateral opening defined in a wall of the tubular structure through which the balloon is inflated to radially expand the tubular structure, after which the balloon is deflated, and then removed from the tubular structure to, thereby, provide a fluid flow path through the tubular structure.

Anastomotic connector and system for delivery

An anastomotic connector comprises a vessel anchor, a midgraft connector and graft material. The vessel anchor has a generally tubular main body including a distal end and a proximal end, the distal end defining a plurality of flanges integrally formed with the tubular main body and being movable from a first loaded position to a second expanded position. The midgraft connector operably couples the graft to the vessel anchor to form an anastomotic connector between an artery and a vein.

Anastomotic connector

An anastomotic connector comprises a generally tubular access port having a first end and a second end, a generally tubular main body portion having a first end and a second end, wherein the second end of the main body portion is positioned adjacent to the second end of the access port such that the main body portion and access port are in fluid communication, and an anchor member received, within the access port and having a plurality of fingers that are extendable from the first end thereof. The fingers of the anchor member are movable between a loaded position wherein the fingers are substantially parallel to a center axis of the access port and an expanded position wherein the fingers are substantially perpendicular to the center axis of the access port.

TAILORED VENOUS ANASTOMOSIS FOR ARTERIOVENOUS GRAFTS

An arteriovenous graft and methods of reducing the risk of graft thrombosis and extending patency of the arteriovenous graft are provided herein. The arteriovenous graft is operable for attaching to a vein at a venous anastomosis. In some aspects, the arteriovenous graft includes a plurality of grooves at a venous anastomosis end of the arteriovenous graft and the venous anastomoses may be arranged such that the arteriovenous graft and the vein meet at an angle of 30° or less. 1. An arteriovenous graft operable for attaching to a vein , the arteriovenous graft comprising:a biocompatible material forming the arteriovenous graft having an arterial anastomosis end and a venous anastomosis end, the arteriovenous graft operable to couple the vein at a venous anastomosis,wherein the venous anastomosis between the venous anastomosis end of the arteriovenous graft and the vein is arranged at an angle from less than 90° to about 13°.2. The arteriovenous graft of claim 1 , wherein the angle of the venous anastomosis is tailored to reduce a vein wall area over which pathologically high and/or pathologically low shear strain rates occur.3. The arteriovenous graft of claim 1 , further comprising a plurality of grooves formed into a surface of the arteriovenous graft adjacent to the venous anastomosis end of the graft.4. The arteriovenous graft of claim 3 , wherein the plurality of grooves are micro-digit grooves.5. The arteriovenous graft of claim 3 , wherein the micro-digit grooves have a width of from about 0.5 mm to about 5.0 mm and a length of from about 1.0 mm to about 10 mm.6. The arteriovenous graft of claim 3 , wherein the surface of the arteriovenous graft comprises three micro-digit grooves.7. The arteriovenous graft of claim 1 , further comprising a lachrymiform indent formed into the surface of the graft adjacent the venous anastomosis end.8. The arteriovenous graft of claim 7 , wherein a plurality of grooves are formed within the lachrymiform indent.9. The ...

HYDROGELS AND USE THEREOF IN ANASTOMOSIS PROCEDURES

This disclosure provides novel hydrogels that can undergo multiple gel-sol transitions and methods of making and using such hydrogels, particularly in anastomosis procedures. The peptide hydrogels comprising a fibrillar network of peptides that are in an amphiphilic β-hairpin conformation. The peptides comprise photo-caged glutamate residues with a neutral photocage that can be photolytically selectively uncaged to disrupt the fibrillar network and trigger an irreversible gel-sol phase transition of the hydrogel. Isolated peptides for making the disclosed hydrogels are provided, as are methods of using the peptide hydrogels in anastomosis procedures. 1. A peptide hydrogel comprising a fibrillar network of peptides , wherein:the hydrogel undergoes a gel-sol phase transition upon application of shear stress, and a sol-gel phase transition upon removal of the shear stress; andthe peptides are in an amphiphilic β-hairpin conformation and comprise photo-caged glutamate residues with a neutral photocage that can be photolytically selectively uncaged to disrupt the fibrillar network and trigger an irreversible gel-sol phase transition of the hydrogel.2. The peptide hydrogel of claim 1 , wherein:the amphiphilic β-hairpin conformation comprises a β-turn, a first β-strand, a second β-strand, a hydrophobic face, and a hydrophilic face;the assembly of the peptides in the fibrillar network comprises hydrophobic interactions between the hydrophobic faces of the peptides;the first β-strand comprises the photocaged glutamate residue, the second β-strand comprises a glycine residue, and the sidechains of the photocaged glutamate residue and the glycine residue are proximal to each other on the hydrophobic faces of the peptides; anduncaging the photocaged glutamate residues disrupts the hydrophobic interactions between the peptides by exposing negative charges of the glutamate residues, thereby disrupting the fibrillar network and triggering the irreversible gel-sol phase transition ...

SYSTEMS AND METHODS FOR PERCUTANEOUS ACCESS AND FORMATION OF ARTERIOVENOUS FISTULAS

A device and method for creating an arteriovenous (AV) fistula includes a proximal base having a distal diagonal end surface and a distal tip connected to the proximal base and movable relative to the proximal base. The distal tip has a proximal diagonal end surface. A heating assembly, including an energized heating element, is disposed one of the distal diagonal end surface and the proximal diagonal end surface. A passive heating assembly is disposed on the mating diagonal end surface. The distal diagonal end surface and the proximal diagonal end surface are adapted to contact opposing sides of a tissue portion to create a fistula. The angle of the proximal diagonal end surface matches the angle of the distal diagonal end surface, so that the two surfaces match one another during deployment. 1. A system for creating an arteriovenous (AV) fistula , comprising:a proximal base having a distal diagonal end surface;a distal tip connected to the proximal base and movable relative to the proximal base, the distal tip having a proximal diagonal end surface, the distal diagonal end surface and the proximal diagonal end surface being adapted to contact opposing sides of a tissue portion to create the fistula;a heating assembly comprising an energizable heating element disposed on at least one of the distal diagonal end surface and the proximal diagonal end surface; anda heat spreader comprising a passive non-energized heat conductive element disposed on the other one of the distal diagonal end surface and the proximal diagonal end surface;wherein a portion of the embedded heater is shaped to a desired blood flow aperture profile and sufficiently raised above the base of the embedded heater so as to cut said profile in the tissue portion, the raised profile being adapted to contact the heat spreader and to conductively communicate heat for the purpose of welding tissues together.2. The system as recited in claim 1 , and further comprising a shaft for connecting the distal ...

Bridge vessels-proximal anastomosis supporting device for coronary artery bypass grafting and manufacturing method thereof

A bridge vessels-proximal anastomosis supporting device for coronary artery bypass grafting and a manufacturing method thereof. The bridge vessels-proximal anastomosis supporting device for the coronary artery bypass grafting comprises an arc-shaped body, an elliptical bottom edge is arranged at the lower part of the arc-shaped body, a circular port is arranged at the right side of the arc-shaped body, a notch is formed between the rightmost end of the bottom edge and the lowermost end of the port, the diameter R of the circular port is 4 mm, 5 mm, 6 mm, 7 mm or 8 mm, the major axis a of the elliptical bottom edge is 13 mm, and the minor axis of the elliptical bottom edge is the same as R. The arc-shaped body is formed by weaving titanium-nickel alloy wires. The bottom edge and the port are provided with a supporting edge made of a heavy metal material, and the supporting edge is fixed with the wires through medical non-absorbable sutures in a wrapping manner. 1. A bridge vessels-proximal anastomosis supporting device for coronary artery bypass grafting comprises an arc-shaped body; an elliptical bottom edge is arranged at the lower part of the arc-shaped body , a circular port is arranged at the right side of the arc-shaped body , and a notch is formed between the rightmost end of the bottom edge and the lowermost end of the port , the diameter R of the circular port is 4 mm , 5 mm , 6 mm , 7 mm or 8 mm , the major axis a of the elliptical bottom edge is 13 mm , and the minor axis of the elliptical bottom edge is the same as R.2. The bridge vessels-proximal anastomosis supporting device for coronary artery bypass grafting as claimed in claim 1 , wherein it is characterized in that: said arc-shaped body is formed by weaving titanium-nickel alloy wires; said wire has an outer diameter of 0.15 mm claim 1 , and the alloy wires in the same direction are parallel to each other and wires in different directions are distinguished by diamond-shaped spacing claim 1 , while ...

DEVICE AND METHOD FOR ASSISTING END-TO-SIDE ANASTOMOSIS

Disclosed herein are embodiments of devices and methods for forming a seal covering an incision in tissue. In some embodiments, a deformable member can be loaded into a catheter and inserted into the tissue incision. The deformable member can unfold into a cup-shape which can form a seal around the incision during a procedure. Once the procedure is finished, the deformable member can be drawn back into the tube. 1. A device for sealing an opening in body tissue , the device comprising:a hollow elongated member comprising a proximal end and a distal end and having a lumen extending therethrough, wherein the distal end of the hollow elongated member is configured to extend through the opening in the body tissue;a shaft member configured to fit within the lumen of the hollow elongated member; anda deformable sealing member coupled to a distal portion of the shaft member at a coupling point, the deformable sealing member comprising a flexible cover portion coupled to the distal portion of the shaft at the coupling point and a sealing ring; in the first configuration, the deformable sealing member is held within the lumen of the hollow elongated member, wherein the coupling point is located distal to the sealing ring;', 'in the second configuration, the deformable sealing member is positioned distal to and outside of the lumen of the hollow elongated member, and wherein movement of the deformable sealing member from the first configuration to the second configuration allows the sealing ring to enlarge to a dimension larger than that of the hollow elongated member, the flexible cover portion having generally a cup-like shape with an opening that faces proximally, wherein the sealing ring when enlarged is configured to seal against body tissue surrounding the opening in the body tissue; and', 'in the third configuration, the deformable sealing member is held within the lumen of the hollow elongated member, wherein the sealing ring is located distal to the coupling point., ...

Full eversion anastomosis juncture formation and suturing

Disclosed embodiments include apparatuses, systems, and methods for facilitating anastomosis between bodily passages. In an illustrative embodiment, an eversion mechanism is configured to engage a first external surface of a receiving passage adjacent a first opening in the receiving passage in order to create a receiving flange presenting a first interior face. A donor support mechanism is configured to support a donor passage with an opening in an end in an everted position that forms a donor flange presenting a second interior face. The donor support mechanism is further configured to present the second interior face of the donor flange against the first interior face of the receiving flange to present a passage juncture. A suturing mechanism is configured to motivate a filament through a helical path around the passage juncture to suture the second interior face of the donor passage to the first interior face of the receiving passage.

ANASTOMOSIS STAPLING/CLIPPING DEVICES, SYSTEMS AND METHODS

An apparatus for performing anastomosis procedures comprises of an end-effector to engage a lumen for attaching a tubular structure to said lumen to create a connective branch or an anastomosis. The apparatus includes a contractible and expandable member coupled to the end-effector to secure engagement of the end-effector with the lumen. A pair of wedge members operates to deploy a staple to attach the tubular structure to the lumen. The pair of wedge members operates in opposing directions to deploy the staple. 1. An apparatus for performing anastomosis procedures , comprising:an end-effector to engage a lumen for attaching a tubular structure to said lumen to create a connective branch or an anastomosis;a contractible and expandable member coupled to the end-effector to secure engagement of the end-effector with the lumen,a pair of wedge members configured to deploy a staple for attaching the tubular structure to the lumen, wherein the pair of wedge members operates in opposing directions to deploy said staple.2. The apparatus of claim 1 , wherein the pair of wedge members operate in a scissor-like motion to deploy said staple.3. The apparatus of claim 1 , wherein the contractible and expandable member provides support to the lumen as the staple is deployed to attach the tubular structure to the lumen.4. The apparatus of claim 1 , wherein the contractible and expandable member is placed in a contracted state when the end-effector is inserted through the lumen for engagement.5. The apparatus of claim 1 , wherein the contractible and expandable member is placed in an expanded state to secure the engagement of the end-effector with the lumen.6. The apparatus of claim 1 , wherein the end-effector can be operated telescopically by extending from a first length to a second length claim 1 , retracting from the second length to the first length claim 1 , or varying at a length between the first length and the second length.7. The apparatus of claim 1 , wherein the end- ...

TRANSCAVAL VENTURI

A device may provide a fluid connection between fluid vessels, such as between an inferior vena cava and an abdominal aorta. The device may include a conduit structure for deployment in a first fluid vessel or a shunt structure for deployment within a passage between the first fluid vessel and a second fluid vessel that is adjacent to the first fluid vessel. The conduit structure may include a narrowed section to which the shunt structure is secured and in fluid connection therewith. 1. A device for providing fluid flow between fluid vessels of a patient , comprising:a conduit structure configured to be implanted within a first fluid vessel, the conduit structure comprising an outer wall defining a conduit lumen extending between a conduit inlet and a conduit outlet, the conduit structure comprising a constricted portion positioned between the conduit inlet and the conduit outlet, the constricted portion comprising a constricted lumen diameter that is less than a diameter of at least one of the conduit inlet or the conduit outlet; anda shunt structure configured to be at least partially implanted within a second fluid vessel that is adjacent to the first fluid vessel and configured to attach to the constricted portion of the conduit structure, the shunt structure comprising a shunt lumen that is configured to be in fluid communication with the conduit lumen.2. The device of claim 1 , wherein the shunt lumen comprises a shunt lumen diameter that is no greater than the constricted lumen diameter.3. The device of claim 2 , wherein the shunt lumen diameter is 0.8 or less of the constricted lumen diameter.4. The device of claim 1 , wherein the shunt structure comprises a shunt anchor configured to be secured to at least a portion of the second fluid vessel.5. The device of claim 4 , wherein the shunt anchor comprises a stent adapted to be radially deployed within the second fluid vessel and placed into contact with a wall of the second fluid vessel.6. The device of claim ...

Transcatheter insertion device and method

The present invention relates to a transcatheter method for providing fluid communication between two anatomical compartments. The present invention also relates to a transcatheter system comprising an intracorporeal connector for fluid communication between two anatomical compartments through at least one anatomical wall, wherein said connector is adapted to receive a flow regulating device, a connector, a flow regulating device and an insertion device.

Cardiac Shunt Device and Delivery System

A shunt device for creating a shunt in an atrial septum includes magnets coupled to inner loops of a coil comprising at least two inner loops and two outer loops, with a diameter of each of the inner loops being less than a diameter of the outer loops. The coil is made of a shape memory alloy (SMA) and is adapted to exert a compressive force upon layers of tissue caught between the inner loops of the coil. The magnets are adapted to provide additional compressive force to adjacent inner loops of the coil, thereby further causing the coil to cut through the layers of tissue and create a shunt. The diameter of the resultant shunt is less than the diameter of the outer loops, thereby preventing the outer two loops from passing through the created shunt. At least one end of the coil has a connection means for connecting with a delivery device. 1. A shunt device for creating a shunt in an atrial septum of a patient , comprising:a wire comprised of a shape memory alloy, wherein the wire is adapted to transform from a substantially straight wire to a coil shape upon heating and wherein the wire, upon transforming to the coil shape, comprises at least two inner loops and at least two outer loops, wherein a diameter of the at least two inner loops are each less than a diameter of each of the at least two outer loops, and wherein the wire, when in the coil shape, is adapted to exert a compressive force upon layers of tissue caught between the at least two inner loops; anda plurality of magnets coupled to the at least two inner loops, wherein the plurality of magnets are adapted to provide a compressive force to adjacent inner loops of the wire in the coil shape, thereby further causing the wire to cut through the layers of tissue and create a shunt of a diameter less than the diameter of the outer loops such that the at least two outer loops do not pass through said shunt.2. The shunt device of claim 1 , wherein at least one end of the wire comprises a connection means for ...

CONNECTOR AND METHOD FOR COUPLING ANATOMICAL WALLS

A connector is provided for fluid communication between two anatomical compartments through at least one anatomical wall, wherein the connector includes a neck adapted and configured to be positioned across the anatomical wall(s); a primary element for securing the neck across the anatomical wall(s); and a secondary element for securing the neck across the anatomical wall(s). A method is also provided for coupling two anatomical walls using said connector. 124-. (canceled)25. A method for coupling two anatomical walls using a connector comprising a neck configured to be positioned across the anatomical wall , and primary means for securing the connector across the anatomical walls , and secondary means for securing the connector across the anatomical walls , the method comprising:securing the neck across the anatomical walls, wherein the connector is secured to the anatomical walls using the secondary securing means prior to securing the connector to the anatomical walls using the primary securing means.26. The method according to claim 25 , wherein the connector can be arranged into a delivery configuration and into a working configuration in which the connector is secured across the anatomical walls.27. The method according to claim 25 , wherein the primary means and/or the secondary means are movable from a delivery position to a working position in which the connector is secured across the anatomical walls.28. The method according to claim 25 , comprising a step of delivering the connector across the anatomical walls using a delivery catheter.29. The method according to claim 25 , wherein the primary securing means comprises a first set of arms and a second set of arms; and the secondary securing means comprises a first set of arms and a second set of arms.30. The method according to claim 29 , comprising a step of deploying the first set of arms of the secondary securing means in the distal compartment.31. The method according to claim 29 , wherein the first ...

JAW ASSEMBLY FOR A VESSEL SEALER

A jaw assembly for vessel sealing device having a pair of jaw member that are pivotally coupled together via two flanges associated with one of the jaw members and a single, centrally positioned flange associated with the other of the jaw members. The flanges include cam slots so that axial movement of a drive shaft can open and close the jaw members. The jaw members may include a knife pathway for axial movement of a knife blade that is positioned to one side of the central flange and thus offset from the central axis of the jaws. 1. A jaw assembly for a vessel sealing device , comprising:a first jaw member having first and second spaced apart flanges;a second jaw member having a single third flange positioned between the first and second flanges of the first jaw member and pivotally connected thereto.2. The jaw assembly of claim 1 , further comprising a drive shaft coupled to the first jaw member and the second jaw member.3. The jaw assembly of claim 2 , wherein the drive shaft is coupled to the first jaw member and the second jaw member by a clevis.4. The jaw assembly of claim 3 , wherein the clevis is coupled to the first and second flanges by corresponding first and second cam slots in the first and second flanges.5. The jaw assembly of claim 4 , wherein the clevis is coupled to the third flange by a third cam slot in the third flange.6. The jaw assembly of claim 5 , wherein first jaw member and the second jaw member are pivotally connected by a pivot pin.7. The jaw assembly of claim 6 , wherein the pivot pin has a shoulder positioned in abutting relation to the third flange of the second jaw member.8. The jaw assembly of claim 7 , wherein the first and second jaw members includes corresponding first and second slots defining a knife pathway.9. The jaw assembly of claim 8 , further comprising a knife blade extending from the drive shaft and to one side of the single third flange.10. The jaw assembly of claim 9 , wherein the knife pathway curves inwardly from a ...

TRANSCATHETER SYSTEM AND METHOD FOR REGULATING FLOW OF FLUID BETWEEN TWO ANATOMICAL COMPARTMENTS

The present invention relates to a transcatheter method for providing fluid communication between two anatomical compartments. The present invention also relates to a transcatheter system comprising an intracorporeal connector for fluid communication between two anatomical compartments through at least one anatomical wall, wherein said connector is adapted to receive a flow regulating device, a connector, a flow regulating device and an insertion device. 1. A transcatheter system comprising an intracorporeal flow regulating device for regulating the flow of fluid between two anatomical compartments through at least one anatomical wall , wherein the flow regulating device comprises means for intracorporeally securing the flow regulating device to an connector intracorporeal connector positioned through said anatomical wall(s).2. The system according to claim 1 , wherein the flow regulating device comprises an actuator to allow or prevent fluid flow through the intracorporeal connector.3. The system according to claim 1 , wherein the flow regulating device comprises a first portion located in use in the first compartment claim 1 , a second portion located in use in the second compartment claim 1 , and an intermediate portion located in use through the anatomical wall(s).4. The system according to claim 3 , wherein the first portion and/or the second portion comprises one or more apertures for fluid passage from the first compartment to the second compartment.5. The system according to claim 3 , wherein the first portion comprises a cross-section of larger diameter than the diameter of the cross-section of the intermediate portion.6. The system according to claim 1 , wherein when the flow regulating device is coupled to the connector claim 1 , fluid can flow from the first compartment to the second compartment claim 1 , and when the flow regulating device is not coupled to the connector claim 1 , fluid is prevented from flowing from the first compartment to the second ...

Anastomosis Devices

Implantable medical devices for connecting tissue layers, such as for connecting a gallbladder and a portion of a gastrointestinal tract to create an anastomosis, include a tubular structure having a plurality of apposition portions, a central region, and a covering material. The devices are endoscopically deployable and may include flange members having hinge members or variable properties such as length, angle, shape, material stiffness, and wire diameter. 1. (canceled)2. An implantable medical device comprising: a barrel portion having a first end and a second end and a tunnel or central aperture therethrough,', 'a first flange portion extending from the first end of the barrel portion, the first flange portion including a plurality of first flange members configured to apply an apposition force against a first tissue side,', 'a second flange portion extending from the second end of the barrel portion, the second flange portion including a plurality of second flange members configured to apply an apposition force against a second tissue side, and the first flange portion and the second flange portion are configured to move independently of each other; and, 'a plurality of struts forminga valve assembly arranged within the barrel portion and configured to allow blood flow through the tunnel or central aperture.3. The implantable medical device of claim 2 , wherein the first flange portion and the second flange portion and configured to anchor the valve assembly and seal against backward flow.4. The implantable medical device of claim 3 , wherein the first flange portion is configured to apply a first apposition force against the first tissue side and the second flange portion is configured to apply a second apposition force against the second tissue side to conform to tissue topography.5. The implantable medical device of claim 4 , wherein the first flange portion and the second flange portion are configured to conform to the tissue topography of heart chambers or ...

Tissue Clip

A tissue clip for adjoining tissues including a body portion, a biasing mechanism interconnecting the body portion to a tissue grasping mechanism, the grasping mechanism having a first condition wherein the grasping mechanism is extending against and away from the body portion and a second condition wherein the grasping mechanism is biased against the body portion. A tissue clip and deployer combination. A method of interconnecting tissue by deploying the tissue clip, puncturing tissue to be interconnected with the tissue clip, and interconnecting the tissue. A method of treating an aneurism by deploying the tissue clip at an aneurism site, closing off the aneurism site with the tissue clip, and treating the aneurism. A method of imaging a surgical procedure with ultrasound by modifying a surface of a metal surgical instrument, and imaging the metal surgical instrument with ultrasound during a surgical procedure. 1. A tissue clip for adjoining tissues , said tissue clip comprising:a body portion;biasing means interconnecting said body portion to tissue grasping means;said grasping means having a first condition wherein said grasping means is extending against and away from said body portion and a second condition wherein said grasping means is biased against said body portion.240. -. (Cancelled) Field of the InventionGenerally, the present invention relates to surgical devices. More specifically, the present invention relates to surgical devices for fastening tissues, closing tissues, and repairing tissues such as a mitral valve.Description of Related ArtMinimally invasive surgery has allowed physicians to carry out many surgical procedures with less pain and disability than conventional, open surgery. In performing minimally invasive surgery, the surgeon makes a number of small incisions through the body wall to obtain access to the tissues requiring treatment. Typically, a trocar, which is a pointed, piercing device, is delivered into the body with a cannula. ...

Intravascular arterial to venous anastomosis and tissue welding catheter

A method of creating an AV fistula between adjacent first and second vessels includes inserting a guidewire from the first vessel into the second vessel. Inserting a catheter including a proximal member and a distal member over the guidewire such that a distal tip of the distal member comes into contact with a selected anastomosis site. Moving the distal member and the proximal member together to clamp tissue surrounding the aperture between the distal face of the proximal member and a proximal face on the distal member. Applying energy to an active heating member on the proximal member to cut and form the aperture, and to weld the edges thereof in order to create a desired fistula between the two vessels. Using a passive heating member disposed on the distal member to create a heating gradient across a tissue contacting surface of the distal member.

ANASTOMOTIC STAPLE WITH CAPILLARY WHICH EXPELS A BONDING AGENT UPON DEFORMATION

A surgical fastener for use with an anastomosis of two tissues includes a base leg and an upright leg. The base leg is selectively deformable and includes a traumatic tip for piecing tissue. The surgical fastener also includes at least one capillary disposed on the base leg which has a reservoir defined therein for retaining a liquid, e.g., bioadhesive, bonding agent, medicament, etc. Each of the capillaries is ruptureable upon deformation of the surgical fastener to dispense the liquid to the anastomosis site. 120-. (canceled)21. A surgical instrument comprising:an actuator assembly; a first leg;', 'a second leg; and', 'a pivot point connecting the first and second legs,', 'at least one capillary disposed on one of the first or second legs, the at least one capillary rupturable upon deformation of the one of the first or second legs to dispense a liquid disposed within the capillary., 'a loading unit coupled to the actuator assembly, the loading unit including a plurality of surgical fasteners, the actuator assembly configured to actuate the loading unit to fire the plurality of surgical fasteners from the loading unit, each surgical fastener of the plurality of surgical fasteners including22. The surgical instrument according to claim 21 , wherein the at least one capillary is disposed in a reservoir defined in one of the first or second legs.23. The surgical instrument according to claim 22 , wherein the liquid disposed within the at least one capillary includes at least one of a bonding agent claim 22 , medicinal agent claim 22 , or therapeutic agent.24. The surgical instrument according to claim 21 , wherein the liquid is selected from the group consisting of an anti-coagulant claim 21 , a bio-adhesive claim 21 , a coagulant claim 21 , an antibiotic claim 21 , a sterilizing solution claim 21 , an anti-inflammatory medication claim 21 , an inflammatory medications claim 21 , an immuno-stimulating agent claim 21 , an antiviral agent claim 21 , and an anti- ...

METHODS AND SYSTEMS FOR COUPLING CONDUITS

Medical devices including vascular access kits and related methods are disclosed. In some embodiments, a vascular access system may include a first conduit, a second conduit, and a connector that is reversibly or irreversibly coupled to both the first and second conduits such that there is a continuous lumen from the first conduit and the second conduit. In some embodiments the vascular access system may include a connector where the inside geometry of the connector enhances laminar flow. The vascular access system, when implanted and assembled, may be a fully subcutaneous surgical implant. 1. A vascular access system , comprising:a first conduit;a second conduit;a connector comprising an inside luminal wall, a first end, a second end, a first connecting member on the first end, and a second connecting member on the second end,the connector being configured to couple to an end of the first conduit and to an end of the second conduit such that there is a continuous lumen from the first conduit to the second conduit; andwherein the connector is configured to decouple from at least one of the first conduit and the second conduit.2. The vascular access system of claim 1 , wherein the first and the second connecting members further comprise securing devices to couple to the first and/or second conduits;wherein a connection between the connector and the first and/or second conduits is fluid tight.3. The vascular access system of claim 2 , wherein the securing devices are configured to compressibly couple the connector to the first and/or second conduits.4. The vascular access system of claim 1 , wherein there is a continuous inside diameter along the connector; andwherein the continuous lumen extends from an artery, a vein, or an arteriovenous graft to a heart of a mammal.5. The vascular access system of claim 1 , wherein the first and/or second conduits are configured with an impermeable wall segment in a portion nearest to the connector.6. The vascular access system of ...

Method for performing a vascular anastomosis

A method for performing a coronary artery bypass graft procedure on a patient to connect a bypass vessel to a target vessel includes the steps of creating an opening in the patient that communicates with the thoracic cavity of the patient; providing a bypass vessel having a lumen and at least one free end; passing the free end of the bypass vessel from the thoracic cavity through the opening to a position outside the body of the patient; attaching a connector to the free end of bypass vessel while the free end of the bypass vessel is outside the body of the patient; passing the free end of the bypass vessel from the position outside the body of the patient through the opening and into the thoracic cavity; and connecting the free end of the bypass vessel to a target vessel with the connector.

Device and method for establishing an artificial arterio-venous fistula

A shunt rivet for implantation in the aorta and inferior vena cava to treat chronic obstructive pulmonary disease, and a method of treating chronic obstructive pulmonary disease. The shunt rivet may be formed to have a central section, a proximal clinch section, and a distal clinch section each having one or more clinch members. These one or more clinch members may be trained to be resiliently biased to bend radially outwardly from the central section.

Implantable tissue connector

An implantable tissue connector comprises a conduit and at least one bulge extending outwardly from the conduit's outer surface in a circumferential direction. At least one blocking ring loosely fitting over the outer surface with a clearance between the outer surface and the blocking ring is provided for mounting tubular living tissue within the clearance. The blocking ring has an inner diameter which is sized relative to an outer diameter of the bulge to prevent the blocking ring from slipping over the bulge when living tissue is mounted within the clearance. During implantation, the conduit is inserted into the tubular part of living tissue and over the bulge. Then, the blocking ring is pushed over the free end of the living tissue against the bulge. The living tissue is secured to the conduit with a self-enhancing effect when the tissue tends to be pulled off of the conduit

DEVICE TO AID IN ARTERIAL MICROVASCULAR ANASTOMOSIS

An everter device to facilitate preparation of ends of arterial segments for end-to-end microvascular anastomosis. The device includes structure that provides sufficient support to prevent unwanted buckling of arterial tissue. The everter device offsets the tendency of the arterial tissue wall to recover its natural shape and fall off securement posts or pins of a coupler ring. The structure may be in the form of an intraluminal catheter balloon. Alternately, the structure may be in the form of a plunger. Alternately, the structure may be in the form of a radially expanding member provided on a shaft. The device further has a contoured surface on an everter end to evert a free end of arterial tissue over a coupler ring, and to cause the posts or pins of the coupler ring to pierce through the everted arterial tissue. The everter end is provided with one or more openings therein, such as a circumferential slot, to receive the posts or pins of the coupler ring. 1. An everter device comprising:an everting member having an everter end;an inflation shaft extending distally of the everter end; andan intralumenal catheter balloon in fluid communication with the inflation shaft.2. The everter device of claim 1 , the everter end having a curved surface.3. The everter device of claim 1 , the everter end having one or more openings therein to accommodate posts or pins of a coupler ring of a microanastomosis clamp system.4. The everter device of claim 3 , the one or more openings including a circumferential slot.5. The everter device of claim 3 , at least one of the one or more openings having a material therein that is piercable claim 3 , deformable claim 3 , or axially recedes claim 3 , when the everter device is advanced into contact with posts or pins of a coupler ring.6. A method for preparing arterial tissue for microanastomosis claim 3 , comprising:providing a coupler ring on an arterial segment, the coupler ring having a plurality of securement pins projecting therefrom, ...

MEDICAL DEVICE AND CORRESPONDING METHOD OF USE FOR ARTERIOVENOUS FISTULA CREATION

A multi-part medical implant device assembly for use in the surgical creation of an arteriovenous fistula is described herein, the implant device having an arterial section with an arterial lumen provided therein, a venous section with a venous lumen provided therein, and a connector section with a connecting lumen provided, the connector section serving to provide a fluid pathway from the arterial section to the venous section. The device may be formed of a top and a bottom portion, where the two-part assembly may facilitate surgical implantation. 1. A medical implant device , comprising:an arterial section that is configured to secure an artery, the arterial section having an arterial lumen provided therein where the arterial section is oriented along an arterial axis and extends from a proximal end to a distal end;a venous section that is configured to secure a vein, the venous section having a venous lumen provided therein, where the venous section is oriented along a venous axis and extends from a proximal end to a distal end; anda connector section, having a connecting lumen provided therein, that is configured to provide a fluid conduit between the arterial section and the venous section, extending between the arterial section and the venous section from an arterial connection region to a venous connection region, where the connector section is oriented about an arterial connection axis in the arterial connection region and oriented about a venous connection axis in the venous connection region.2. The medical implant device of claim 1 , wherein the arterial axis and the venous axis are parallel to one another.3. The medical implant device of claim 1 , wherein the arterial connection axis is perpendicular to the arterial axis claim 1 , and wherein the venous connection axis is coaxial with the venous axis.4. The medical implant device of claim 1 , wherein the arterial section claim 1 , the venous section and the connector section are generally tubular.5. The ...

A Kit for Placing a Bypass

A kit for placing a bypass between two body vessels (R, L) of a patient comprises two catheters (), two guide wires () moveable within one of the catheters () each and a bypass element delivery system () for holding a bypass element (). The bypass element delivery system () is moveable along the first guide wire () and the bypass element delivery system () is capable of releasing and setting free the bypass element (). The kit further comprises an expansible element () being capable of connecting with the bypass element delivery system (), of moving the bypass element delivery system () towards the opposite end of the first guide wire () and of setting the bypass element delivery system () free. The inventive kit enables an atraumatic placement of a bypass. 1. A kit for placing a bypass between a first and a second body vessel of a patient , the kit comprisinga first catheter with a first delivery end and a second catheter with a second delivery end,a first guide wire moveable within the first catheter, the first guide wire having a first end region being moveable to the first delivery end, the first guide wire having an opposite end being opposite to the first end region,a second guide wire moveable within the second catheter, the second guide wire having a second end being moveable to the second delivery end, the second end of the second guide wire being a catch for capturing the first guide wire and for moving the first guide wire into the second catheter with a first end region of the first guide wire first, anda bypass element delivery system for holding a bypass element, the bypass element delivery system being moveable along the first guide wire from the first end region of the first guide wire, wherein the bypass element delivery system is capable of releasing and setting free the bypass element,wherein the kit comprises an expansible element the expansible element being capable of connecting with the bypass element delivery system and of moving the bypass ...

Method and apparatus for coupling left ventricle of the heart to the anterior interventricular vein to stimulate collateral development in ischemic regions

A method for stimulation of collateral development in ischemic cardiac regions comprises the fluid coupling of the left ventricle of the heart to the anterior interventricular vein to stimulate collateral development in ischemic regions. The fluid coupling of the left ventricle of the heart to the anterior interventricular vein includes a control of the diastolic/systolic pressure in the venous system to be within about 20 - 50 mmHg. The fluid coupling of the left ventricle of the heart to the anterior interventricular vein includes inserting a transmyocardial conduit into the left ventricle and a tri-directional coupler attached to the anterior interventricular vein. An associated apparatus for stimulation of collateral development in ischemic cardiac regions via the fluid coupling of the left ventricle of the heart to the anterior interventricular vein is disclosed.

ANASTOMOSIS DEVICE WITH COLLAPSIBLE DISTAL HEAD ELEMENT

A surgical instrument for bonding body tissue includes an instrument shank or shaft, a first tool element, a second tool element axially movable relative to the first tool element, and an annular sleeve-like cutting element. The second tool element includes a plurality of tool element members that are radially deflectable. The first and second tool elements are each equipped with at least one electrode. The second tool element includes a biasing member that biases the tool element members in a radially inward direction. A stop member is operable in a first position to hold the tool element members against the biasing force of the biasing member in which the tool element members assume a maximum outer diameter. The stop member is further operable in a second position to release the tool element members such that the tool element members can deflect radially inwardly and cut body tissue. 1. A surgical instrument for bonding body tissue in a hollow organ , the surgical instrument comprising:an instrument shank or shaft having a distal end and a first tool element fixedly arranged on the distal end of the instrument shank or shaft;a second tool element positioned distally from the first tool element and supported by the instrument shank or shaft to be axially movable relative to the first tool element; andan annular sleeve-like cutting element being held in an axially moveable manner for cutting body tissue,the second tool element comprising a plurality of tool element members in the form of arms that are radially deflectable, the tool element members protruding at least in part in a radial direction and spaced apart from each other in a circumferential direction,the first and second tool elements each equipped with at least one electrode having or generating an annular shape,the second tool element comprising a biasing member that exerts a biasing force to bias the tool element members in a radially inward direction and an axially moveable retaining disk arranged at a ...

ANASTOMOTIC CONNECTOR

An anastomotic connector is disclosed that includes a connector body having a first end engageable into a first vessel, the first end being provided with teeth on its outer surface, and a first locking sleeve engageable around the first end, the first locking sleeve surrounding the teeth in a locked position, in order to impede relative movement between the first vessel and the connector body. The first locking sleeve is provided with longitudinal ribs on its inner surface, the ribs being spaced from each other in a circumferential direction of the first locking sleeve. 1. An anastomotic connector comprising:a connector body having a first end engageable into a first vessel, the first end being provided with teeth on an outer surface thereof, anda first locking sleeve engageable around the first end, the first locking sleeve surrounding the teeth in a locked position, in order to impede relative movement between the first vessel and the connector body,{'b': '30', 'wherein the first locking sleeve is provided with longitudinal ribs () on an inner surface thereof, the ribs being spaced from each other in a circumferential direction of the first locking sleeve.'}2. The anastomotic connector of claim 1 , wherein the teeth are arranged on the outer surface in at least two circumferential rows spaced from each other.3. The anastomotic connector of claim 2 , wherein the two rows of teeth are spaced from each other by a first distance claim 2 , wherein the ribs have a length greater than or equal to the first distance claim 2 , and wherein the ribs extend over the rows of teeth in the locked position.4. The anastomotic connector of claim 1 , wherein the first locking sleeve is provided with through holes or slots extending from the inner surface to the outer surface of the first locking sleeve.5. The anastomotic connector of claim 1 , wherein the first locking sleeve and the first end are provided with a locking system that maintains the first locking sleeve in a fixed ...

Magnetically Activated Arteriovenous Access Valve System and Related Methods

In one aspect, an arteriovenous access valve system may generally include a first valve configured to be positioned at or adjacent to an end of arteriovenous graft and a second valve configured to be positioned at or adjacent to an opposite end of the arteriovenous graft. In addition, the system may include an actuator assembly in fluid communication with the first and second valves. The actuator assembly may include a housing, a driver assembly positioned within the housing and a drive magnet positioned within the housing. The drive magnet may be rotatably coupled to the driver assembly such that, when the drive magnet is rotated, the driver assembly is configured to be rotatably driven so as to supply fluid to the first and second valves or to draw fluid out of the first and second valves depending on a rotational direction of the driver assembly.

DEVICES AND METHODS FOR OCCLUDING OR PROMOTING FLUID FLOW

Devices and methods for occluding or promoting fluid flow through openings are disclosed. In one exemplary embodiment an occlusion device is provided having an expandable outer elongate tubular body, a guide member extending from a distal end of the outer body, and a slide tube disposed within the outer body, the proximal portions of the outer body and the slide tube being fixedly mated. The slide tube is configured to slide distally within the outer tubular body when the tubular body is expanded to form wings. A tether can be included as part of the device and it can be used to assist in positioning and locking a location of the device in an opening. Exemplary methods for delivering devices disclosed herein are also provided. 1. A method for repairing a valve , the method comprising:advancing a first tubular assembly into a first opening within a first portion of a valve, the first tubular assembly having a first elongate tubular body and a first inner tube extending partially therethrough, the first elongate tubular body having distal and proximal portions;applying force to the first elongate tubular body to move the first elongate tubular body relative to the first inner tube to thereby cause the distal and proximal portions of the first elongate tubular body to expand and form respective distal and proximal wings;advancing a second tubular assembly into a second opening within a second portion of the valve, the second tubular assembly having a second elongate tubular body and a second inner tube extending partially therethrough, the second elongate tubular body having distal and proximal portions;applying force to the second elongate tubular body to move the second elongate tubular body relative to the second inner tube to thereby cause the distal and proximal portions of the second elongate tubular body to expand and form respective distal and proximal wings; andmoving the first and second tubular assemblies toward each other to bring the first and second ...

FIXATION OF VESSELS FOR PERCUTANEOUS FISTULA CREATION

A method of percutaneously creating a fistula includes inserting percutaneously a medical instrument to a target location having a first blood vessel and a second blood vessel. A fastener is then deployed via the medical instrument to the target location. The fastener is in a first configuration before the deploying and a second configuration after the deploying. The fastener limits relative movement between the first blood vessel and the second blood vessel when in the second configuration. An anastomosis between the first blood vessel and the second blood vessel is percutaneously produced. 1. A method of percutaneously creating a fistula , comprising:inserting percutaneously a medical instrument to a target location having a first blood vessel and a second blood vessel;deploying, via the medical instrument, a fastener to the target location, the fastener being in a first configuration before the deploying, the fastener being in a second configuration after the deploying, the fastener limiting relative movement between the first blood vessel and the second blood vessel when in the second configuration; andproducing percutaneously an anastomosis between the first blood vessel and the second blood vessel.2. The method of claim 1 , wherein:the deploying the fastener causes relative movement between the first blood vessel and the second blood vessel to place a side wall of the first blood vessel into engagement with a side wall of the second blood vessel; andthe side wall of the first blood vessel being maintained in engagement with the side wall of the second blood vessel after the deploying.3. The method of claim 1 , wherein:the medical instrument includes a needle;the fastener is a flexible member attached to the needle; and advancing the needle within the target location to surround at least a portion of each of the first blood vessel and the second blood vessel with a portion of the flexible member;', 'fixating a first end of the flexible member to a first portion ...

Anastomosis Devices

An implantable medical device for connecting tissue layers, such as connecting tubular tissues to create an anastomosis, includes a single elongate member and a covering material. The devices provided may also be used for other purposes including, but not limited to, partially or fully occluding openings in tissue, temporarily or permanently holding generally planar layers of tissue together, aneurysm repair, and the like. 1. A medical device for creating an anastomosis between a first body conduit and a second body conduit , the device comprising: a first apposition portion configured to conform to a geometry of a first tissue surface of the first body conduit and to provide an apposition force against the first tissue surface;', 'a second apposition portion configured to conform to a geometry of a second tissue surface of the second body conduit and to provide an apposition force against the second tissue surface; and', 'a central portion disposed between the first apposition portion and the second apposition portion, the central portion defining a lumen therethrough; and, 'a frame comprising an elongate member defininga covering material disposed on at least a portion of the central portion, the covering material being configured to allow material flow through the lumen and between the first body conduit and the second body conduit,wherein said frame has a contracted configuration and an expanded configuration;wherein said central portion has a diameter, andwherein said diameter of said central portion is substantially the same in said contracted configuration and said expanded configuration.2. The device of claim 1 , wherein the elongate member is wound in a pattern where (1) the elongate member defines a first feature claim 1 , (2) the elongate member traverses the central portion claim 1 , (3) the elongate member defines a second feature claim 1 , and (4) the elongate member traverses the central portion claim 1 , andwherein the elongate member repeats the ...

External support for elongated bodily vessels

External support implant for unbound covering of a blood vessel graft in a peripheral vascular bypass system. The implant includes: elongate body having a longitudinal axis, and interior collapsible upon exterior of the blood vessel graft. Elongate body includes tubular fabric having intertwined coiled compression springs configured for elastically resisting longitudinal compression of the elongate body from a relaxed length, when compression springs are slightly stressed, and for elastically increasing diameter of the elongate body when compression springs are subjected to the longitudinal compression.

SYSTEM FOR PERFORMING INTRALUMINAL CORONARY AND METHOD OF OPERATION THEREOF

A method of performing a coronary bypass procedure, the method may be performed by the flexible apparatus controlled by at least one controller, the method may include acts of: percutaneously situating the flexible apparatus into a first artery coupled to connective tissue of a chest wall; transluminally detaching at least a portion of the first artery from the connective tissue by applying ultrasound signals of a first type emitted by at least one transducer of the flexible apparatus; steering at least a portion of the detached portion first artery from a current location to a bypass location at a target artery by applying a force transmitted through the flexible apparatus situated within the first artery; and coupling, by the flexible apparatus situated within the first artery, the first artery to the target artery at the bypass location to establish flow communication between the first artery and the target artery. 1. A method of performing a bypass procedure , the method performed by a flexible apparatus controlled by at least one controller , the method comprising acts of:percutaneously situating the flexible apparatus through a first artery (LIMA) which is coupled to connective tissue of a chest wall;transluminally detaching at least a portion of the first artery surrounding the flexible apparatus to thereby detach the first artery from the connective tissue of the chest wall by applying ultrasound signals of a first type emitted by a plurality of elongated spherical transducers arranged longitudinally in a row rotationally coupled to a distal end of the flexible apparatus while rotating the plurality of elongated spherical transducers about a longitudinal axis of the flexible apparatus to transluminally detach at least a portion of the first artery surrounding the flexible apparatus from the connective tissue;driving at least on e of the plurality of elongated spherical transducers to emit ultrasound signals of the first type to transluminally fractionate the ...

SYSTEM AND METHOD FOR SCAFFOLDING OF ANASTOMOSES

Embodiments of the invention provide systems and methods for using a tissue scaffold to facilitate healing of an anastomosis. One embodiment provides a tissue scaffold for placement at an anastomotic site within a body lumen comprising a radially expandable scaffold structure having lateral and mid portions, at least one retention element coupled to each lateral portion and a barrier layer. The retention element engages a luminal wall when the scaffold structure is expanded to retain the structure and exert a compressive force on the anastomosis. The mid portion has a greater radial stiffness than the lateral portions such that when the structure is expanded, the lateral portions engage tissue prior to the mid portion. The barrier layer is configured to engage a luminal wall when the structure is expanded to provide a fluidic seal at the anastomosis. The barrier layer may also include releasable biological agents to promote anastomotic healing. 1. A method for healing of an anastomosis in a target body lumen , the method comprising:positioning a prosthetic scaffold at an anastomotic site in the target body lumen;radially expanding the prosthetic scaffold to engage a wall of the target body lumen;utilizing the prosthetic scaffold to apply a compressive force on the wall of the target body lumen to maintain opposing like tissue layers of the anastomosis in substantial alignment; andretaining the prosthetic scaffold at the anastomotic site during a period of anastomotic healing.2. The method of claim 1 , wherein the prosthetic scaffold includes a barrier layer claim 1 , the method further comprising:engaging the barrier layer with the wall of the target body lumen to form a fluidic seal between the anastomosis and the barrier layer.3. The method of claim 1 , wherein the prosthetic scaffold includes a biological agent claim 1 , the method further comprising:delivering the biological agent to the anastomotic site to facilitate healing of the anastomosis.4. The method of ...

ENDOLUMINAL STAPLER WITH ROTATING WHEEL CAM FOR MULTI-STAPLE FIRING

A surgical stapler has a body, a shaft assembly extending distally from the body, and an end effector coupled with a distal end of the shaft assembly. The end effector has a stapling head assembly, an anvil, and a vacuum port. The vacuum port is operable to draw tissue between the stapling head assembly and the anvil. The anvil is operable to move toward and away from the stapling head assembly to thereby capture the tissue drawn between the stapling head assembly and the anvil. The stapling head assembly comprises a plurality of wheel assemblies and staple cartridges. At least one wheel assembly is operable to rotate to thereby move the anvil toward and away from the body. The remaining wheel assemblies are operable to rotate to thereby drive staples through the captured tissue. The body includes user input features operable to drive the wheel assemblies. 1. A surgical instrument comprising:(a) a body;(b) a shaft assembly extending distally from the body, wherein the shaft assembly comprises a proximal end and a distal end; and (i) a stapling head assembly, wherein the stapling head assembly comprises a staple and a first rotary member, wherein the first rotary member is rotatable about a first axis,', '(ii) an anvil, wherein the first rotary member is operable to drive the staple toward the anvil, wherein the anvil is operable form the staple, and', '(iii) a vacuum head, wherein the vacuum head is operable to draw tissue between the stapling head assembly and the anvil., '(c) an end effector coupled with the distal end of the shaft assembly, wherein the end effector comprises2. The surgical instrument of claim 1 , wherein the stapling head assembly comprises a plurality of staples.3. The surgical instrument of claim 2 , wherein the stapling head assembly further comprises a plurality of rotary members claim 2 , wherein each rotary member is operable to drive a corresponding staple of the plurality of staples toward the anvil.4. The surgical instrument of claim 3 , ...

SUTURE-FREE CLASP FOR VASCULAR ANASTOMOSIS

A suture-free clasp for vascular anastomosis, which relates to the technical field of vascular anastomosis. The clasp comprises a first end part (), a second end part (), a rotating shaft (), a binding belt () and a rotation-stopping structure (). The rotating shaft () is rotationally installed on the first end part (); and one end of the binding belt () is fixed to the rotating shaft (), and the other end of the binding belt () is fixed to the second end part (). The second end part () is configured to be able to buckle with the first end part (); and the rotation-stopping structure () is arranged between the first end part () and the rotating shaft (), and the rotation-stopping structure () is configured to be able to lock the rotating shaft () on the first end part (). The suture-free clasp for vascular anastomosis reduces the influences of human factors of doctor during vascular anastomosis on the knotting position and knotting strength, thereby solving the technical problems in the prior art in which knotting operations are difficult, pseudoaneurysms occur since slipping happens easily during knotting which then causes blood leakage, and readjustments are difficult after knotting is complete.

Systems and methods for a fluid carrying conduit of a vascular access system

Systems and methods for a blood conduit for fluidly coupling a first vascular segment to a second vascular segment are disclosed herein. In one embodiment, a system for fluidly coupling proximal and distal tubular segments of a fluid conduit in a cardiovascular system is provided. The system may include a first engagement feature disposed on a distal end of the proximal tubular segment. The system also may include a second engagement feature disposed on a proximal end of the distal tubular segment. The first engagement feature may be configured to mate with the second engagement feature. In this manner, continuous flow may be provided between the proximal and distal tubular segments of the fluid conduit. In another embodiment, the proximal and distal tubular segments of the fluid conduit may collectively form a single unitary lumen without a connection device interposed between the segments.

SYSTEMS AND METHODS FOR PERCUTANEOUS ACCESS AND FORMATION OF ARTERIOVENOUS FISTULAS

A catheter system includes a proximal base having a distal diagonal end surface and a distal tip connected to the proximal base and movable relative to the proximal base, wherein the distal tip has a proximal diagonal end surface. The distal diagonal end surface and the proximal diagonal end surface contact opposing sides of a tissue portion to create the fistula. A peripheral edge defines the proximal distal end surface. A proximal point is disposed on the peripheral edge. The proximal point comprises a shortened angle and a fully radiused edge relative to a remaining portion of the peripheral edge and a relief recess is disposed on a distal end of the proximal base, both for the purpose of minimizing tissue snagging. 1. A catheter system for creating an arteriovenous (AV) fistula , comprising:a proximal base having a distal diagonal end surface;a distal tip connected to the proximal base and movable relative to the proximal base, the distal tip having a proximal diagonal end surface, the distal diagonal end surface and the proximal diagonal end surface being adapted to contact opposing sides of a tissue portion to create the fistula;a peripheral edge defining said proximal distal end surface; anda proximal point on said peripheral edge, wherein said proximal point comprises a shortened angle and a fully radiused edge relative to a remaining portion of said peripheral edge.2. The catheter system as recited in claim 1 , and further comprising a relief recess disposed on a distal end of the proximal base.3. The catheter system as recited in claim 2 , wherein the catheter system is disposed along an operating axis and the relief recess is peripherally spaced from the proximal point on an opposed side of the axis relative to the proximal point.4. The catheter system as recited in claim 1 , and further comprising a sheath disposed about said proximal base claim 1 , the sheath having a distal end wherein a portion of the sheath distal end is disposed on said relief ...

SURGICAL STAPLER FOR AORTIC ANASTOMOSIS

A method for connecting a graft vessel to a target vessel may involve advancing a guidewire of a surgical stapler into the target vessel through an opening at a first location on the target vessel, coupling a stapler cartridge carrying the graft vessel with an anvil of the surgical stapler, activating the anvil to staple the graft vessel to the target vessel at a second location on the target vessel, removing the guidewire from the target vessel, and closing the opening in the target vessel. 1. A surgical stapler used to connect a graft vessel to a target vessel , the stapler comprising:a handle;a flexible shaft coupled to said handle;an anvil positioned at a distal end of said flexible shaft; anda guidewire extending distally from said anvil.2. The surgical stapler of claim 1 , further comprising a graft-holding staple cartridge removably coupled to said anvil.3. The surgical stapler of claim 2 , wherein said staple cartridge further comprises at least two graft clamps configured to hold an end of the graft vessel.4. The surgical stapler of claim 2 , wherein said staple cartridge includes a plurality of staples claim 2 , said staples arranged in four discrete spaced-apart rows.5. The surgical stapler of claim 4 , wherein said handle further comprises an actuator configured to drive said staples into the graft vessel and the target vessel.6. The surgical stapler of claim 1 , wherein said guidewire is fabricated from nickel-titanium alloy.7. The surgical stapler of claim 1 , wherein the distal end of said guidewire is pointed.8. The surgical stapler of claim 1 , wherein said guidewire is between 2 centimeters and 20 centimeters in length.9. A surgical stapler used to connect a graft vessel to a target vessel claim 1 , the stapler comprising:a handle;a shaft coupled to said handle;an anvil positioned at a distal end of said flexible shaft;a guidewire extending distally from said anvil; anda staple cartridge removably coupled to said anvil.10. The surgical stapler of ...

DEVICE AND METHOD FOR ESTABLISHING AN ARTIFICIAL ARTERIO-VENOUS FISTULA

A shunt rivet for implantation in the aorta and inferior vena cava to treat chronic obstructive pulmonary disease, and a method of treating chronic obstructive pulmonary disease. 1. An intravascular connector , comprising:a first pair of clinch members comprising a first member and a second member;a second pair of clinch members comprising a first member and a second member;wherein the first member of the first pair has a length which is less than the second member of the first pair,wherein the first member of the second pair has a length which is less than the second member of the second pair, andwherein the first member of the first pair is positionable within a first vessel and the first member of the second pair is positionable within a second vessel.2. The connector of claim 1 , wherein each first member is sized to arc within each respective vessel.3. The connector of claim 1 , further comprising a clip connector extending between the first and second pair of clinch members and defining a lumen therethrough fluidly coupling the first and second vessels.4. The connector of claim 1 , wherein a portion of the first member of the first pair or the second pair is bioabsorbable.5. The connector of claim 1 , wherein the first member of the first pair of clinch members is configured to swing from a distal position to a proximal position against a tissue wall of the first vessel.6. The connector of claim 5 , wherein the first member of the second pair of clinch members is configured to swing from a distal position to a proximal position against a tissue wall of the second vessel.7. The connector of claim 1 , wherein each clinch member is positionable sequentially in a predetermined order within the first vessel and second vessel.8. A method for implanting an intravascular connector claim 1 , comprising:advancing an intravascular connector through a first vessel, wherein the intravascular connector comprises a first pair of clinch members comprising a first member and a ...

Methods, systems and devices for treating cardiac arrhythmias

Provided is a method of treating cardiac arrhythmia in a patient. The method comprises selecting a patient suffering from a cardiac arrhythmia and creating a flow pathway between a first vascular location and a second vascular location. The first vascular location comprises a source of arterial blood and the second vascular location comprises a source of venous blood. Systems and devices for creating a flow pathway are also provided.

METHOD FOR CONFIGURING AN ARTERIOVENOUS FISTULA

An embodiment of the invention relates to a method of configuring blood vessels at an anastomosis, the method comprising: ensheathing a segment of a transected first blood vessel in a lumen of a sleeve so that an open end of the segment protrudes from a sleeve end; suturing edges of an incision made in a second blood vessel to the open end of the first blood vessel to create an anastomosis; and sliding the sleeve along the first blood vessel to position the sleeve at the anastomosis. 1. A method of configuring blood vessels at an anastomosis , the method comprising:ensheathing a segment of a transected first blood vessel in a lumen of a sleeve having an end connected to a coupler, the coupler comprising a mount configured to be seated on a second blood vessel, so that an open end of the first blood vessel segment protrudes from the sleeve end and the mount;suturing edges of an incision made in a second blood vessel to the open end of the first blood vessel segment to create an anastomosis; andsliding the sleeve and coupler along the first blood vessel to seat the mount onto the second blood vessel at the anastomosis.2. The method according to claim 1 , wherein seating the mount further comprises one or a combination of:closing a brace incorporated in the mount around the second blood vessel; andsuturing or bonding the coupler to the second blood vessel.3. The method according to further comprising:configuring the sleeve from a longitudinally compressed state having a first diameter greater than that of the first blood vessel to a longitudinally expanded state having a diameter smaller than the that of the first blood vessel in order to enclose the portion of the first blood vessel firmly in the lumen of the sleeve.4. The method according to claim 1 , wherein the coupler is configured to deform the second blood vessel to have a non-circular cross section.5. The method according to claim 1 , wherein the coupler is configured to hold the sleeve claim 1 , relative to ...

MINIMALLY INVASIVE SURGICAL APPARATUS AND METHODS

Apparatus and methods are described for performing percutaneous catheter-based interventional surgery. The apparatus comprises first and second devices that are located in adjacent body cavities, such as adjacent blood vessels, the first device being capable of transmitting a directional signal that can be received by the second device. The direction of the signal is correlated with the facility to direct therapy, such that improved accuracy in therapy placement is thereby achieved. Methods for treating patients utilising the means and apparatus are also provided. 148.-. (canceled)49. A system for treating vasculature by forming a fistula , the system comprising: a longitudinal axis;', 'an ultrasound signal transducer mounted at a non-parallel angle relative to the longitudinal axis, the ultrasound signal transducer configured to transmit an ultrasound signal at the non-parallel angle and along a directional path in a cone having position uncertainty less than 5 mm, the ultrasound signal configured to penetrate tissue outside the stenosed artery,', 'an outer sheath,', 'a lumen within the outer sheath,', 'an aperture in the outer sheath, the aperture proximal to the ultrasound signal transducer, the aperture in communication with the lumen, and', 'a needle deployable from inside the lumen to outside the lumen through the aperture and along a deployment path that is aligned with the directional path of the ultrasound signal; and, 'a launching catheter configured to be inserted in a stenosed artery, the launching catheter comprising an omnidirectional ultrasound signal receiving transducer, and', 'a reflecting cone configured to direct the ultrasound signal onto the omnidirectional ultrasound signal receiving transducer, wherein detection of the ultrasound signal by the omnidirectional ultrasound signal receiving transducer indicates that deploying the needle will exit the stenosed artery, traverse tissue between the stenosed artery and the vein, and will enter the ...

INSERTABLE PROSTHESIS AND PROSTHESIS BOARD FOR ANASTOMOSIS

Prosthetic devices are provided used for anastomosis of extremity with lateral, extremity with extremity and lateral with lateral without clamping and sutureless or with quick clamping sutureless, in which the graft is inserted in at least one of the intraluminal parts of the tubular member of the insertable prosthesis, the flanges including lateral inserts allowing the configuration of different prosthesis sets. Also described is a board of prostheses including one flange with multiple holes through which intraluminal parts or occluders will be inserted, according to the need of the anastomosis to be carried out. Also provided are prostheses in which the grafts cover only externally their extraluminal parts. 1. A prosthesis comprising a fixed flange and a tubular member having a conical internal form , and at least one pleated external head having a rigid extremity , wherein the at least one head has a low-profile configuration and is alignable , mobile and provides a variable internal diameter.2. The prosthesis according to claim 1 , wherein the prosthesis is a rigid claim 1 , single-piece prosthesis composed of a calibered intraluminal part whose lumen has a conical shape and is continuous with an outer part claim 1 , comprising heads claim 1 , separated from the intraluminal part by a low profile rigid flange claim 1 , which contains at least two diametrically opposed orifices claim 1 , wherein the caliber at an origin point of the intraluminal part is equal to the sum of internal calibers of the heads.3. The prosthesis according to wherein the flange further comprises lateral reinforcement through holes arranged about a periphery thereof.4. The prosthesis according to claim 3 , wherein the through holes are D-shaped and are arranged in pairs claim 3 , one hole immediately adjacent the other thereby forming a double hole.5. The prosthesis according to claim 1 , further comprising an anastomotic trunk claim 1 , which may be made with autologous claim 1 , ...

ANASTOMOTIC COUPLER

An anastomotic coupler is provided. A ring can include a plurality of receiving portions. A fixation device includes a cartridge. The cartridge includes a plurality of fasteners. Upon actuation of the fixation device, the fasteners puncture the tubular structure. The fasteners are received by the receiving portions such that the tubular structure is coupled with the ring. 1. An anastomotic coupler comprising:a ring including a receiving portion;a fixation device including a cartridge, the cartridge including a body and a plurality of fasteners extending from the body at an angle,wherein the ring is aligned with the cartridge,wherein upon actuation of the fixation device, the plurality of fasteners puncture the tubular structure,wherein the plurality of fasteners are received by the receiving portion such that the tubular structure is coupled with the ring.2. The anastomotic coupler of claim 1 , wherein the fixation device includes a stop claim 1 , the stop extending radially from the housing such that a free end of the tubular structure abuts the stop.3. The anastomotic coupler of claim 1 , wherein upon actuation of the fixation device claim 1 , the fasteners rotate in relation to the tubular structure.4. The anastomotic coupler of claim 1 , wherein a sheath is provided to cover the fasteners until the cartridge is positioned inside the tubular structure.5. The anastomotic coupler of claim 4 , wherein the sheath is removed to uncover the fasteners after the cartridge is positioned inside the tubular structure.6. The anastomotic coupler of claim 1 , wherein upon actuation of the fixation device claim 1 , the body of the cartridge expands radially against the tubular structure.7. The anastomotic coupler of claim 1 , wherein the angle of the fasteners in relation to the body is greater than 0 degrees and less than 90 degrees.8. The anastomotic coupler of claim 1 , wherein one row of fasteners is provided on the cartridge.9. The anastomotic coupler of claim 1 , wherein ...

END TO END ANASTOMOTIC CONNECTOR

An end-to-end anastomotic connector is provided. The anastomotic connector includes solely an arterial connector and a venous connector. The inner diameter of the proximal end of the arterial connector is sized to directly receive the proximal end of the venous connector in an interference fit without the need for a graft material therebetween. The arterial connector and the venous connector are implanted in an artery and vein, respectively, to form a co-axial relationship with the respective vessel. 1. An anastomotic connector solely comprising:an arterial connector having a distal arterial end co-axially implantable into an arterial passageway and a proximal arterial end, wherein an outer diameter of said distal arterial end is larger than an outer diameter of said proximal arterial end, anda venous connector having a distal venous end co-axially implantable into a venous passageway and a proximal venous end, wherein an outer diameter of the distal venous end is larger than an outer diameter of the second venous end,wherein the outer diameter of the proximal venous end is smaller than the inner diameter of the proximal arterial end, and further wherein the inner diameter of the proximal arterial end is sized to directly receive the proximal venous end in an interference fit without the need for a graft material therebetween.21. The anastomotic connector of clam wherein said venous connector and said arterial connector include an anchoring device that extends radially outwardly at an acute angle from a longitudinal axis of a tubular main body at the first end thereof.3. The anastomotic connector of wherein said anchoring device is configured to lie adjacent a venous vessel wall.4. The anastomotic connector of wherein said anchoring device is configured to penetrate a venous vessel wall to seat said device in a venous or arterial passageway.5. The anastomotic connector of wherein said venous connector and said arterial connector are coated with a fluid impermeable ...

Endovascular anastomotic connector device, delivery system, and methods of delivery and use

An endovascular anastomotic connector and method of using the same. The endovascular anastomotic connector includes a vascular conduit and a supply conduit. The vascular conduit has proximal and distal ends that reside within a vascular structure. The supply conduit extends at an angle from the vascular conduit. The proximal end of the supply conduit is configured to be attached to an auxiliary device.

SYSTEMS AND METHODS FOR PERCUTANEOUS INTRAVASCULAR ACCESS AND GUIDEWIRE PLACEMENT

A device for allowing passage of a guidewire from a primary blood vessel to an adjacent secondary blood vessel includes a main body having a primary lumen and a secondary lumen, and a piercing member disposed in the secondary lumen, and configured to be moved distally out of the secondary lumen, and to pierce through tissue while being distally moved. A third lumen located within the piercing member is configured to allow placement of a guidewire from the primary blood vessel to the adjacent secondary blood vessel. In one embodiment, the secondary lumen is configured to allow articulation of the distal end of the piercing element. The piercing member has a sharp point on one end to facilitate cutting a small communicating aperture from the primary blood vessel to the secondary blood vessel. 1. A device for creating intravascular access and guidewire placement , comprising:a main body having a first lumen;a piercing member disposed in said lumen, and configured to be moved distally out of said lumen and to pierce through tissue while being distally moved;a handle attached to said main body and having an actuator for moving said piercing member;a second lumen within the piercing member; anda guidewire disposed in said second lumen for delivery into a desired site from a distal end of said second lumen.2. The device as recited in claim 1 , wherein the piercing member has a sharp point on one end thereof.3. The device as recited in claim 1 , and further comprising a third lumen within said main body claim 1 , outwardly of the first lumen.4. The device as recited in claim 2 , wherein the piercing member is retractable into the first lumen.5. The device as recited in claim 4 , wherein the third lumen is defined by a needle guide having shape memory properties claim 4 , the needle guide being actuatable to a curved orientation by adjustment of a position of the main body to create an incrementally adjustable radius of curvature on the needle guide.6. The device as recited ...

VENTRICULAR ASSIST DEVICE AND RELATED METHODS

A method and system are provided for percutaneously gaining access to oxygenated blood with one or more anastomosis devices and pumping such oxygenated blood directly to the aorta adjacent to the right atrium or left atrium via a VAD system. In one embodiment, a VAD system can be implanted with open surgery. 1. A system to assist a left ventricle of a heart , the system comprising:an anastomosis device coupled to a septum between two chambers of the heart and providing a flow path between the two chambers;a flow path including at least one conduit and configured to flow oxygenated blood from at least one of the left atrium and the left ventricle, through the anastomosis device, through the superior vena cava and back to an artery;a pumping device coupled with the at least one conduit; anda filament coupled to the anastomosis device, wherein the filament exhibits sufficient length to extend from the anastomosis device through the superior vena cava and to an access point associated with at least one of a jugular vein and a subclavian vein.2. The system of claim 1 , wherein the at least one conduit includes:a first conduit coupled with the anastomosis device and extending through the superior vena cava; anda second conduit extending through one of a brachial artery, a carotid artery, a subclavian artery, and a axillary artery and having an outlet disposed in an aortic artery.3. The system of claim 2 , wherein the pumping device is coupled between the first conduit and the second conduit.4. The system of claim 1 , wherein the pumping device is coupled between the anastomosis device and the at least one conduit.5. The system of claim 1 , wherein the pumping device is coupled directly to the anastomosis device.6. The system of claim 1 , wherein the anastomosis device is shaped and configured to be substantially flush with a left wall of the septum.7. The system of claim 1 , wherein a portion of the anastomosis device protrudes past a left wall of the septum claim 1 , and ...

Device and Method for the Application of a Curable Fluid Composition to a Bodily Organ

The invention relates to a device suitable for application of a curable fluid composition to encircle a bodily organ. The device comprises a monolithic piece of a flexible material having a length dimension with an inner surface and an outer surface, a first end and a second end, a width dimension, and two spaced-apart sides, wherein a portion of the length dimension proximal to the first end is configured to contact a portion of the length dimension proximal to the second end, the inner surface defining a hollow area between the two spaced-apart sides; and at least one inlet providing fluid communication between the outer surface and the inner surface, for introduction of the fluid into the hollow area. The device deployable around the bodily organ such that when the portion of the length dimension proximal to the first end contacts the portion of the length dimension proximal to the second end, an outer surface of the bodily organ and the hollowed area define an enclosed volume encircling the bodily organ, the enclosed volume suitable for containing the fluid therein. 120-. (cancel)21. A device suitable for application of a curable fluid composition to encircle a bodily organ , the device comprising:a monolithic piece of a flexible material having a length dimension with an inner surface and an outer surface, a first end and a second end, a width dimension, and two spaced-apart sides, wherein a portion of said length dimension proximal to said first end is configured to contact a portion of said length dimension proximal to said second end,said inner surface defining a hollow area between said two spaced-apart sides; andat least one inlet providing fluid communication between said outer surface and said inner surface, for introduction of said fluid into said hollow area,the device deployable around said bodily organ such that when said portion of said length dimension proximal to said first end contacts said portion of said length dimension proximal to said second ...

MAGNETICALLY-LOCALIZABLE, IMPLANTABLE ARTERIO-VENOUS GRAFT DEVICES

Disclosed are vascular access devices, implantable dialysis grafts, and systems that include them useful in facilitating easy, accurate and reproducible cannulation or needle entry into an implantable device such as a hemodialysis graft, by localizing a portion of the implanted graft that contains one or more paramagnetic materials that operably define the physical boundaries of the target cannulation site/entry port by passage of an external magnetic detector wand over that portion of the patient's body into which the device has been implanted. 1. A biocompatible arterio-venous graft device adapted and configured to connect an artery to a vein in a mammal , the device comprising: (a) a first lumen that is adapted and configured to conduct fluid through the length of the conduit between its first and its second ends, and', '(b) a plurality of localizing rings, each comprised of a substantially ferromagnetic material and extending circumferentially around a distinct portion of the conduit along its longitudinal axis; and each member of the plurality spaced substantially consistently along the length of the conduit, wherein at least two adjacent localizing rings of the plurality define a selected site for cannulation into the conduit; and', 'wherein the first end of the substantially tubular conduit is anastomosed in an “end-to-end”fashion to the artery, and wherein the second end of the substantially tubular conduit is anastomosed in an “end-to-end”fashion to the vein, and wherein the selected cannulation site is capable of being penetrated by a single needle or cannula, or, simultaneously by two or more needles or cannulae, or a combination thereof., 'a substantially tubular conduit of a selected length, and comprised of a biocompatible material, the conduit having2. The biocompatible arterio-venous graft device of claim 1 , wherein the plurality of localizing rings comprises at least three members claim 1 , each positioned circumferentially along the longitudinal ...

Implanted magnets retrieval system and method

A method of retrieving a pair of previously implanted magnets from a patient's body includes maneuvering a guide catheter, which includes a guide magnet affixed to its distal end, toward the implantation site of the implanted magnets. The guide magnet is magnetically coupled to one of the implanted magnets in an orientation in which a through hole of the guide magnet is in register with through holes of the first and second implant magnets. An elongate capture member is slid through the lumen of the guide catheter until one of a proximal segment and a distal segment extends through the through holes of the guide magnet and the implanted magnets. An abutment segment of the elongate capture member, which separates the proximal segment and the distal segment is maneuvered into contact with the magnets. Then, the abutment segment, the guide magnet and the implanted magnets are moved as a group away from the implantation site.

ANASTOMOSIS DEVICE

Provided is an anastomosis arrangement for joining two opposite stumps of a tubular organ in a streamlined anastomosis procedure. The arrangement includes a pair of axially symmetric stump-coupling members that accommodate pairs of counterpart suturing needles, linked together by common suturing threads, and manipulable by a needle-manipulation element to extract the needles tips from the stump-coupling members for piercing walls of the stump. 1. Anastomosis arrangement for joining two stumps of a tubular organ , comprising:a coupling assembly and suturing units incorporated within the assembly; a pair of axially-symmetric coupling members defining two opposite axially-extending stump-coupling projections, each of said projections being configured for coupling with one of the stumps by pulling walls of the stump over external surface thereof to a suturing state in which the stump walls cover a stump-engaging portion thereof,', 'two opposite sets of open channels, one in each of said stump-coupling members arranged in an axially-symmetric manner about the axis, each of the channels (i) extending between a rear channel end in said member and a front channel end in the stump-engaging portion of the projection to define a channel axis, (ii) being defined between side walls and a bottom wall that is configured with a pivot point in a mid-channel portion to define a front channel portion and a rear channel portion, and (iii) having a counterpart in the opposite set that extends along the same channel axis in an opposite direction to the opposite stump-coupling portion, and comprises', 'two needles manipulation elements, one in each stump-coupling member, each being axially displaceable between a front position nearer said stump-coupling projection and a rear, needle extraction position;, 'the coupling assembly comprises'} a suturing thread and two curved suturing needles, each with a tipped front and a thread-coupled rear that is coupled to the thread,', 'the suturing ...

FLUID BYPASS CONDUIT FOR LEFT ATRIAL PRESSURE MANAGEMENT

A method of managing left atrial pressure involves advancing a delivery catheter to a right atrium of a heart of a patient via a transcatheter access path, advancing the delivery catheter through an interatrial septum wall into a left atrium of the heart, deploying a distal end of a bypass fluid conduit from the delivery catheter, anchoring the distal end of the bypass fluid conduit to a pulmonary vein, withdrawing the delivery catheter through the interatrial septum wall, thereby exposing at least a portion of a medial segment of the bypass fluid conduit in the left atrium, anchoring a proximal end of the bypass fluid conduit to the interatrial septum wall, and withdrawing the delivery catheter from the heart. 1. A method of managing left atrial pressure , the method comprising:advancing a delivery catheter to a right atrium of a heart of a patient via a transcatheter access path;advancing the delivery catheter through an interatrial septum wall into a left atrium of the heart;deploying a distal end of a bypass fluid conduit from the delivery catheter;anchoring the distal end of the bypass fluid conduit to a pulmonary vein;withdrawing the delivery catheter through the interatrial septum wall, thereby exposing at least a portion of a medial segment of the bypass fluid conduit in the left atrium;anchoring a proximal end of the bypass fluid conduit to the interatrial septum wall; andwithdrawing the delivery catheter from the heart.2. The method of claim 1 , further comprising channeling blood from the pulmonary vein to the right atrium through the bypass fluid conduit.3. The method of claim 2 , wherein said channeling the blood from the pulmonary vein to the right atrium effects a reduction in left atrial pressure.4. The method of claim 1 , wherein said anchoring the distal end of the bypass fluid conduit to the pulmonary vein comprises embedding one or more barb tissue anchors associated with the distal end of the bypass fluid conduit into biological tissue ...

ENDOVASCULAR STENT GRAFTS AND METHODS OF USING SAID STENT GRAFTS

AN endovascular stent graft including a hydrogel capable of retarded swelling when coming into contact with blood upon implantation in a patient is provided. Methods for the treatment of aneurysms and the prevention of ischemic neurological damage, in particular spinal cord damage, in patients receiving aneurysm repair procedures, using said endovascular stent grafts is also provided. 1. An endovascular stent graft comprising an area having one or more through holes coated at least partially with a hydrogel capable of retarded reduction of the diameter of or retarded occlusion of said through holes by swelling upon implantation in a subject.2. The endovascular stent graft of claim 1 , wherein said area having one or more through holes is a porous membrane.3. The endovascular stent graft of claim 1 , wherein said area having one or more through holes is a textile porous membrane.4. The endovascular stent graft of claim 3 , wherein said textile porous membrane is a warp knitted textile mesh structure.5. The endovascular stent graft of claim 2 , wherein said porous membrane is impregnated with at least one agent claim 2 , selected from the group consisting of chemokines claim 2 , growth factors claim 2 , pharmaceuticals claim 2 , co-factors claim 2 , and functional micro- or nanoparticles.10. The endovascular stent graft of claim 6 , wherein Rin formula (I) is methyl.11. The endovascular stent graft of claim 6 , wherein said acrylate-based crosslinker comprising an internal disulfide moiety is present in an amount of at least about 10 mol-% claim 6 , based on the hydrogel composition.12. The endovascular stent graft of claim 6 , further comprising at least one agent claim 6 , selected from the group consisting of chemokines claim 6 , growth factors claim 6 , pharmaceuticals claim 6 , co-factors claim 6 , and functional micro- or nanoparticles.13. A method for the repair of an aneurysm in a subject claim 1 , comprising the step of implanting the endovascular stent graft ...

VASCULAR ANASTOMOSIS DEVICE AND VASCULAR ANASTOMOSIS METHOD

A vascular anastomosis device comprises two rings with pins and an openable ring holder, which is made of a pair of components and detachably holds the rings. The end portion of a large-diameter blood vessel is inserted through a ring and the vascular wall is extended outward and impaled on the pins, the end portion of a small-diameter blood vessel is inserted through the other ring, and an incision is made from the end surface of the small-diameter blood vessel. The two rings are elliptically deformed so that the minor axis agrees with the diameter of the small-diameter blood vessel, the small-diameter blood vessel is elliptically opened and the vascular wall is extended outward and impaled on the pins, and the two rings are joined together by allowing the pins provided on the ring in one component to stick into the ring in the other component. 1. A vascular anastomosis device for anastomosing two blood vessels with different diameters , the device comprisinga first ring with pins and a second ring with pins both made of a material which is deformable by an external force and allows the pins to stick thereinto; andan openable ring holder, which is made of a pair of components, detachably holds the first ring with pins and the second ring with pins, and has a means for deforming the rings with pins,wherein vascular anastomosis can be achieved in the following manner:the ring holder holding the rings is opened,an end portion of a large-diameter blood vessel is inserted through the first ring and the vascular wall is extended outward 90 degrees and impaled on the pins,an end portion of a small-diameter blood vessel is inserted through the second ring,an incision is made in a longitudinal direction from the end surface of the small-diameter blood vessel,the first ring and the second ring are deformed into a same elliptical shape by the means for deforming the rings so that the minor axis agrees with the diameter of the small-diameter blood vessel,the small-diameter ...

Tissue management apparatus for vascular access

Tissue management methods can include inserting a clamping device into a vessel and clamping a vessel wall via the clamping device. Tissue can be dilated about the clamping device and an anastomotic device provided to the vessel.

Biological tissue connection and repair devices and methods of using same

The instant invention provides compositions and methods for promoting the repair and/or growth of biological tissue, e.g., tubular biological tissue such as nerves. Specifically, the instant invention provides tissue connection devices and tissue repair devices and methods for using these devices.

FITTING FOR RECEIVING AND FIXING A SLEEVE FOR ENFORCING THE END OF A HOLLOW ORGAN

A fitting for receiving and fixing at least one sleeve for enforcing an end of a hollow organ so that said end of the hollow organ can be connected with a further end of the hollow organ, the fitting having a cylindrically shaped body, said body being configured to receive and hold two sleeves with turned-over hollow organ ends so that inner sides of the hollow organ ends make contact with one another. 1. A fitting for receiving and fixing at least one sleeve for enforcing an end of a hollow organ so that said end of the hollow organ can be connected with a further end of the hollow organ , the fitting comprising:a cylindrically shaped body, andsaid body being configured to receive and hold two sleeves with turned-over hollow organ ends so that inner sides of the hollow organ ends make contact with one another.2. The fitting according to claim 1 , wherein the body is completely or partially slit in a longitudinal direction in order to allow or to facilitate the insertion of the two sleeves.3. The fitting according to claim 1 , wherein the body is a ring that is completely or partially slit in a longitudinal direction and comprises a fenestration that permits observation of the ends of the hollow organs introduced into the fitting.4. The fitting according to claim 2 , wherein the fit of said sleeve for enforcing the end of the hollow organ and of the fitting for accommodating two sleeves allows a press fit claim 2 , an interference fit or a push fit.5. The fitting according to claim 1 , wherein the body has a curved profile or a U-profile along a longitudinal axis so as to encompass two sleeves with turned-over hollow organ ends over their entire lengths claim 1 , wherein the inner sides of the hollow organ ends make contact with one another.6. The fitting according to claim 1 , wherein the body is configured to receive and hold a sleeve having a cylindrical shape and being configured to be pushed over the end of the hollow organ and for turning-over the end of the ...

ANASTOMOSIS DEVICES

Implantable medical devices for connecting tissue layers or occluding body conduits and tissue structures include apposition portions, a central region, and a covering material. The methods of using the devices include endoscopic deployment, and the devices may include self-expanding frameworks that facilitate a secure connection between the tissue structures. In some embodiments, one or more tethers are used to longitudinally contract the device in situ. 120.- (canceled)21. A medical device comprising:a delivery catheter;an implantable device positioned on the delivery catheter, the implantable device including a first end, a second end opposite the first end, and a central portion that is selectively longitudinally contractible and positioned between the first end and the second end;a tether extending from the first end to longitudinally collapse the central portion; anda containing member positioned about the implantable device configured to contain the implantable device while the implantable device is in a delivery configuration.22. The medical device of claim 21 , wherein the implantable device further includes a covering member positioned about the central portion.23. The medical device of claim 21 , wherein the tether is formed of one of PTFE claim 21 , nylon claim 21 , and combinations thereof.24. The medical device of claim 21 , wherein the tether is a multifilament construct.25. The medical device of claim 24 , wherein the tether includes at least one of a braided construct and a twisted construct.26. The medical device of claim 21 , wherein the tether includes a low elasticity material.27. The medical device of claim 21 , wherein the tether includes a monofilament material.28. The medical device of claim 21 , wherein the tether is routed through the central portion.29. The medical device of claim 21 , further comprising a locking member operable to retain the anastomosis device in a longitudinally contracted configuration.30. The medical device of claim ...

Adjustable shunts and associated systems and methods

The present technology is directed to adjustable interatrial shunting systems that selectively control blood flow between the left atrium and the right atrium of a patient. The adjustable interatrial devices include a shunting element having an outer surface configured to engage native tissue and an inner surface defining a lumen that enables blood to flow from the left atrium to the right atrium when the system is deployed across the septal wall. The systems can include an actuation assembly for selectively adjusting a geometry of the lumen and/or a geometry of a lumen orifice to control the flow of blood through the lumen.

METHODS AND DEVICES FOR TISSUE SUTURING

A suturing device is disclosed. The suturing device includes an end effector assembly disposed on a distal end of the suturing device. The end effector assembly includes at least one guide tube housing at least one elongated member, a guide rack, and an anchor configured for disposal in a tubular tissue circumferentially offset from the guide rack. The anchor includes at least one guide tube attached to a suture having a first end and a second end. The at least one elongated member is deployed to puncture tubular tissue and mate with the at least one aperture of the anchor such that extraction of the at least one elongated member simultaneously draws out the suture through the punctured tubular tissue. 1. A suturing device for tubular tissue , comprising:a handle assembly including a trigger assembly;an elongated shaft extending from the handle assembly; and at least one guide rod extending distally from the elongated shaft;', 'at least one first guide tube extending distally from the elongated shaft, the at least one first guide tube housing at least one elongated member;', 'a guide rack disposed on the guide rod, the guide rack having at least one first aperture configured for locating the at least one guide rod and at least one second aperture configured for locating the at least one first guide tube; and', 'at least one aperture housing a second guide tube, the second guide tube attached to a suture having a first end and a second end; wherein a first actuation of the trigger assembly longitudinally extends the anchor into an incision in tubular tissue and longitudinally advances the guide rack such that tubular tissue is captured between the guide rack and the anchor and a second actuation of the trigger assembly deploys the at least one elongated member to puncture tubular tissue and mate with the at least one aperture of the anchor such that extraction of the at least one elongated member simultaneously draws out the first end of the suture through the ...

DEVICES AND METHODS FOR FORMING VASCULAR ACCESS

The invention generally relates to catheter systems and methods for guided formation of vascular access sites (such as fistulas and grafts). According to certain aspects, a catheter system for forming a vascular access site include an elongate body comprising a distal end and configured to be inserted into a first vessel. The elongate body includes an exit port along its side that is proximal to the distal end. An imaging assembly is associated with the elongate body and configured to generate image data of the first vessel and a second vessel positioned next to the first vessel. For vascular access formation, a penetrating member of the catheter system extends out of the exit port and through a wall of the first vessel and a wall of the second vessel. 1. A catheter system for forming a vascular access site through a wall of the first vessel and a wall of the second vessel , the catheter system comprising:an elongate body comprising a distal end and an exit port adjacent the distal end of the elongate body;an imaging assembly associated with the elongate body and configured to generate image data of the first vessel and the second vessel;a needle configured to extend out of the exit port of the elongate body and through the wall of the first vessel and the wall of the second vessel, wherein the needle comprises a distal tip, an opening at the distal tip and an interior lumen extending from the distal tip; anda cauterizing element capable of extending through the opening of the distal tip of the needle.2. The catheter system of claim 1 , wherein the cauterizing element is capable of extending through the opening of the distal tip of the needle while the needle is extending out of the exit port of the elongate body.3. The catheter system of further comprising a guidewire configured to extend out of the opening of the needle.4. The catheter system of further comprising an anastomotic device configured to be inserted over the guidewire and into a fistula.5. The catheter ...

SYSTEMS AND METHODS FOR CREATING ARTERIOVENOUS (AV) FISTULAS

A system for creating an arteriovenous (AV) fistula comprises a vessel access sheath having a hollow interior and an exit port, a side access needle catheter configured to fit within the hollow interior of the sheath, a needle configured to be inserted into a blood vessel through the side access needle catheter, a toggle delivery catheter configured to fit within the hollow interior of the sheath, and a toggle apparatus configured to be delivered into a vessel through the toggle delivery catheter. The toggle apparatus comprises a shaft and a toggle member pivotably attached to a distal end of the shaft. A source of RF energy or resistive heat energy may be provided for application to the toggle member and/or to a heater insert in the toggle delivery catheter, for the purpose of creating the fistula. 1. A device for creating an arteriovenous (AV) fistula , comprising:a first member comprising a main body having a primary lumen and a secondary lumen;a second member comprising a piercing member disposed in said secondary lumen, and configured to be moved distally out of said secondary lumen, and to cut through tissue while being distally moved; anda third member extending from a distal end of the piercing member and being actuatable to move adjacent first and second blood vessels toward one another and to create an elongated communicating aperture in opposing sides of each of the first vessel and the second vessel, the third member comprising a needle which is extendable from a distal end of the piercing member into a distal end of the primary lumen of the main body.26-. (canceled)7. The device as recited in claim 1 , and further comprising apparatus disposed in said primary lumen for retracting in a proximal direction said needle.8. A method of creating an AV fistula between adjacent first and second blood vessels claim 1 , comprising:positioning a first member comprising a main body of a device within the first vessel;extending a second or piercing member distally ...

VASCULAR ANASTOMOSIS STENT

Provided herein are devices, methods, and kits for a stent based anastomosis. 1. A vascular anastomosis stent device comprising:a) A biocompatible elongated tube structure comprising a first and second open end, the tube structure having an inside surface facing a central axis of the tube structure and an outside surface facing away from the central axis, wherein the inside surface of the elongated tube is continuous between the first and second open end;b) a first radially expandable metallic ring encircling the tube structure at or near the first open end; andc) a second radially expandable metallic ring encircling the tube structure at or near the second open end.2. The stent device of claim 1 , further comprisinga) a third open end, wherein the inside surface of the elongated tube structure is continuous between the first, second, and third open end; andb) a third radially expandable metallic ring encircling the elongated tube at or near the third open end.3. The stent device of claim 1 , wherein the radially expandable metallic rings are partially embedded in the outside surface of the elongated tube structure and do not extend to the inside surface.4. The stent device of claim 1 , wherein the radially expandable metallic rings comprise a circumferential groove.5. The stent device of claim 1 , wherein the radially expandable metallic rings comprise a ratcheting mechanism that permits expansion but not collapse of the rings.6. The stent device of claim 1 , wherein the radially expandable metallic rings comprise a plastically deformable metal.7. The stent device of claim 1 , wherein the radially expandable metallic rings are expandable by a balloon catheter.8. The stent device of claim 1 , wherein the radially expandable metallic rings have a radial stiffness when expanded sufficient to resist deformation when circumferential force sufficient to provide a hermetical seal between the radially expandable metallic rings and a vascular wall is applied.9. The stent ...

Delivery system for implantable flow connector

A delivery system for delivering an implant to a first space within a body of a patient including an elongate delivery member having a proximal portion, a distal portion, a lumen and a receiving area, the receiving area dimensioned for receipt of the implant. A deforming member is movable with respect to the delivery member from a first position to a second position to apply a force to the implant to deform the implant positioned in the receiving area of the delivery member.

SUTURING APPARATUS AND METHOD

Disclosed embodiments include apparatuses, systems, and methods for driving a needle to facilitate suturing, such as may be performed in a surgical anastomosis procedure. In an illustrative embodiment, an apparatus includes a frame configured to counter-rotatably support two generally parallel rollers. A first roller supported by the frame has a flat surface configured to rollably engage a first face of a shaft of a helically-shaped needle. A second roller supported by the frame has a grooved surface defining a groove that is configured to at least partially receive a second face of the shaft. The bottom of the groove has a bottom width at least as wide as the second face and bounded by sides extending to a groove opening at the grooved surface having a surface width that is wider than the second face. 1. An apparatus comprising:a frame configured to counter-rotatably support two generally parallel rollers;a first roller supported by the frame, the first roller having a flat surface configured to rollably engage a first face of a shaft of a helically-shaped needle; anda second roller supported by the frame, the second roller having a grooved surface defining a groove that is configured to at least partially receive a second face of the shaft, a bottom of the groove having a bottom width at least as wide as the second face and bounded by sides extending to a groove opening at the grooved surface having a surface width that is wider than the second face.2. The apparatus of claim 1 , wherein the surface width of the groove opening is generally the same as the bottom width of the bottom of the groove.3. The apparatus of claim 2 , wherein the surface width and the bottom width are approximately 40 percent wider than the second face.4. The apparatus of claim 1 , wherein the surface width is larger than the bottom width and both of the sides of the groove flare outwardly from the bottom of the groove to the groove opening at the grooved surface.5. The apparatus of claim 4 ...

Methods and Devices for Utilizing Bondable Materials

The invention primarily relates to fastening and stabilizing tissues, implants, and/or bondable materials, such as the fastening of a tissue and/or implant to a bondable material, the fastening of an implant to tissue, and/or the fastening of an implant to another implant. This may involve using an energy source to bond and/or mechanically to stabilize a tissue, an implant, a bondable material, and/or other biocompatible material. The invention may also relate to the use of an energy source to remove and/or install an implant and/or bondable material or to facilitate solidification and/or polymerization of bondable material.

Implantable flow connector

A system for coupling a first space within a body of a patient with a second space within the body of the patient including a flow connector insertable into the first and second spaces within the body and having a conduit having a wall forming a lumen therein and first and second orifices. A first retention member is engageable with a first portion of the first space within the body and has a first opening, and the flow connector is positioned within the first opening. A second retention member is engageable with the second space within the body, the second retention member has a second opening and the flow connector is positioned within the second opening. The second retention member interlocks with the first retention member.

METHODS, SYSTEMS AND DEVICES FOR TREATING ERECTILE DYSFUNCTION

Provided are methods, systems and devices for treating erectile dysfunction in a patient. A patient is selected that exhibits erectile dysfunction. A flow pathway is created between a first vascular location comprising a source of arterial blood and a second vascular location comprising a source of venous blood. 1selecting a patient exhibiting erectile dysfunction; andcreating a flow pathway between a first vascular location and a second vascular location;wherein the first vascular location comprises a source of arterial blood;wherein the second vascular location comprises a source of venous blood;wherein the method is constructed and arranged to treat erectile dysfunction.. A method of treating erectile dysfunction in a patient, comprising: This application is a continuation of PCT Application No. PCT/US2014/044601 (Attorney Docket No. 29919-712.301), filed Jun. 27, 2014, which claims priority under 35 USC 119(e) to U.S. Provisional Patent Application Ser. No. 61/840,365, entitled “Methods, Systems and Devices for Treating Erectile Dysfunction”, filed Jun. 27, 2013, which is incorporated herein by reference by its entirety. This present application, while not claiming priority to, may be related to: U.S. Pat. No. 7,828,814, entitled “Device and Method for Establishing an Artificial Arterio-Venous Fistula”, filed Apr. 4, 2007; U.S. Non-Provisional application Ser. No. 11/152,621, entitled “Devices for Arterio-Venous Fistula Creation”, filed Jun. 13, 2005; U.S. Pat. No. 8,016,782, entitled “Methods for Providing Oxygenated blood to Venous Circulation”, filed Jun. 13, 2005; U.S. Non-Provisional application Ser. No. 11/946,454, entitled “Devices, Systems, and Methods for Creation of a Peripherally Located Fistula”, filed Nov. 28, 2007; U.S. Pat. No. 8,382,697, entitled “Devices, Systems, and Methods for Peripheral Arteriovenous Fistula Creation”, filed Jan. 22, 2008; U.S. Non-Provisional application Ser. No. 12/752,397, entitled “Device and Method for Establishing an ...

Vascular anastomosis device and method

Techniques associated with a vascular anastomosis device are described, including a lower flange having a lower gripping surface and an interior surface, a diversion conduit attached to the lower flange, the diversion conduit having a lumen extending between an inlet and an outlet, the inlet forming an opening in the interior surface, an upper flange having an upper gripping surface, and being configured to move from a first position to a second position with respect to the lower flange, the first position being characterized by the upper flange being separated from the lower flange, the second position being characterized by the upper gripping surface being in contact with the lower gripping surface, and a biasing structure configured to exert a force on the upper flange in a direction from the first position toward the second position.

Medical connector device

The present invention provides devices for connecting biological structures. The device features a tubular member that includes a tubular body. The tubular member may include a plurality of interwoven lengths configured for reversible radial enlargement and reversible radial contraction of the tubular member. In some aspects the tubular member may include a net design of interconnected cells configured for reversible radial enlargement of the tubular member. The tubular member includes a distal opening, a proximal opening, a central cavity within the tubular member for receiving and retaining a biological structure and a plurality of spaced apart protrusions protruding out from the exterior surface of the body of the device for fixing to the device an end of the biological structure and for fixing a second structure to the device to facilitate connecting the biological structure to the second structure.

A shaft-pushed fastenable suture

A shaft-pushed fastenable suture configured for suturing a first tissue with a second tissue and/or for ligation of blood vessels and/or hollow structured organs. The fastenable suture characterized by an elongated flexible cord with one or more teeth, protruding from same. The fastenable suture further comprises a male-head at the distal end and an accepting female-head at the proximal end. The male-head is in connection with an anchor. The anchor configured to be temporarily accommodated by a distal end of a pushing-shaft. The female-head comprises a suture accepting-channel and a neighboring pushing-shaft accepting-channel. At least one of the two accepting-channels comprising one or more flexible pawls for both allowing, by means of the teeth, a continuous linear forward motion of the male-head and the cord within the accepting-channel in only one direction, while preventing motion of the male-head and cord in a backward direction and allowing only the pushing-shaft a reversible reciprocal motion.

Anchoring screw device

A mechanical device for anchoring hollow tube-like structures in the human body, such as blood vessels and ureters. It facilitates positioning needles or catheters in blood vessels and it prevents those from dropping out of the vessel or from “wandering off” in the vessel. The device can be used in every interventional medical situation for diagnostic or therapeutic purposes. The device is very easy to fix onto the vessel wall. Screwing is a fast technique saving operating time and requiring only basic microsurgical skills.

METHODS, SYSTEMS AND DEVICES FOR TREATING HYPERTENSION

Provided is a method of treating arterial hypertension in a patient. The method comprises selecting a patient suffering from arterial hypertension and creating a flow pathway between a first vascular location and a second vascular location. The first vascular location comprises a source of arterial blood and the second vascular location comprises a source of venous blood. The method causes a reduction in diastolic pressure and a reduction in systolic pressure; and the reduction in diastolic pressure is to an extent at least approximating the reduction in systolic pressure. Systems and devices for creating a flow pathway are also provided. 1. A method for treating a disease or disorder in a patient , the method comprising:advancing a vessel-to-to vessel guidewire through a starting vessel to a target vessel with a needle delivery device;advancing a flow creation device over the advanced vessel-to-vessel guidewire to be positioned through vessel walls of the starting vessel and the target vessel; and (i) moving a control of a handle of the clip deployment catheter from a first ready to deploy position to a first deployed position, thereby causing the outer sheath of the clip deployment catheter to retract a first distance relative to a distal tip of the clip deployment catheter while the anastomotic clip is held stationary relative to the distal tip, allowing at least one distal arm of the anastomotic clip to deploy,', '(ii) moving the control from the first deployed position to a second ready to deploy position, and', '(iii) moving the control from the second ready to deploy position to a second deployed position, thereby causing the outer sheath of the clip deployment catheter to retract a second distance relative to the distal tip of the clip deployment catheter while the anastomotic clip is held stationary relative to the distal tip, allowing at least one proximal arm of the anastomotic clip to deploy., 'creating a flow path between the starting vessel and the ...

Devices and methods for providing passage between heart chambers

A device for providing a passage between a first and second heart chamber is provided. The device includes a middle region having first and second ends, a lumen extending therethrough having a longitudinal axis, a first end region coupled to the first end, and a second end region coupled to the second end. The first end region may be delivered in the first heart chamber in a compressed state and transitioned to a deployed state, the first end region being deformable such that portions of the first end region are expandable to different angles relative to the longitudinal axis. The second end region may be delivered in the second heart chamber in a compressed state and transitioned to a deployed state therein, the second end region being deformable such that portions of the second end region are expandable to different angles relative to the longitudinal axis.

ENDOVASCULAR FIXATION DEVICE

An endovascular fixation device includes a first portion and a second portion connected to the first portion to define a central lumen extending longitudinally through the portions. The first portion includes a first radially expandable ring and at least one first connector, connected to the first ring, configured to cause at least one first flarable crown of the first ring to flare radially outwardly relative to other portions of the first ring when the first ring is expanded from a retracted position to an expanded position. The second portion includes a second radially expandable ring and at least one second connector, connected to the second ring, configured to cause at least one second flarable crown of the second ring to flare radially outwardly relative to other portions of the second ring when the second ring is expanded from a retracted position to an expanded position. 147-. (canceled)48. An endovascular fixation device comprising:a radially expandable middle portion comprising a plurality of struts;a plurality of first flarable crowns forming a first radially expandable ring, wherein the first flarable crowns are configured to flare radially outwardly relative to the middle portion when the fixation device is expanded from a retracted position to an expanded position; anda plurality of second flarable crowns forming a second radially expandable ring, wherein the second flarable crowns are configured to flare radially outwardly relative to the middle portion when the fixation device is expanded from the retracted position to the expanded position,wherein, upon expansion of the fixation device from the retracted position to the expanded position, the first flarable crowns flare radially outwardly relative to the middle portion so as to form a plurality of first flared crowns and the second flarable crowns flare radially outwardly relative to the middle portion so as to form a plurality of second flared crowns.49. The endovascular fixation device of claim 48 ...

Pulmonary arterial compliance enhancement and control device

Devices and methods for increasing a patient's pulmonary arterial compliance are disclosed. The devices include catheters designed to create a connection between a patient's venous anatomy and the patient's pulmonary artery. With the arteriovenous connection various devices can be implanted in order to increase the volumetric compliance of the pulmonary artery. The devices include collapsible and expandable mechanisms which allow the effective pulmonary arterial volume to expand during systole and contract during diastole. The devices may include a balloon or balloon-like implants which cyclically shuttle a working fluid from the pulmonary artery to the vein and back. The devices may be adjustable to provide desired hemodynamic benefits. Methods are disclosed for making and using the inventive devices.

LYMPHANGIOGENESIS INDUCING DEVICE

A lymphangiogenesis inducing device includes: a puncture member including a distal end portion configured to puncture living tissue, and a through hole penetrating the puncture member along a central axis and extending from the distal end portion toward a proximal end; and a rod-shaped body inserted into the through hole and configured to be moved so as to protrude from the distal end portion. The rod-shaped body includes a shaft portion, and a wound imparting structure including at least one protrusion located on the shaft portion and configured to impart a wound to the living tissue. 1. A lymphangiogenesis inducing device comprising:a puncture member comprising a distal end portion configured to puncture living tissue, and a through hole penetrating the puncture member along a central axis and extending from the distal end portion toward a proximal end; anda rod-shaped body inserted into the through hole and configured to be moved so as to protrude from the distal end portion, wherein:the rod-shaped body comprises a shaft portion, and a wound imparting structure comprising at least one protrusion located on the shaft portion and configured to impart a wound to the living tissue.2. The lymphangiogenesis inducing device according to claim 1 , wherein:the at least one protrusion comprises a plurality of protrusions protruding outward from the shaft portion.3. The lymphangiogenesis inducing device according to claim 2 , wherein:the plurality of protrusions comprises protrusions located at different axial positions and different circumferential positions of the shaft portion.4. The lymphangiogenesis inducing device according to claim 2 , wherein:the protrusions have the same protruding height from the shaft portion in a state in which the protrusions are located in the through hole and in a state in which the protrusions are located outside the through hole.5. The lymphangiogenesis inducing device according to claim 2 , wherein:the protrusions have a protruding height ...

Coupling System, Applicator Tool, Attachment Ring and Method for Connecting a Conduit to Biological Tissue

A coupling system includes an applicator tool and an attachment ring mounted on the applicator tool. Clips are contained within the applicator tool and are deployed through the attachment ring in order to anchor the attachment ring to biological tissue. When deployed, tips of the clips follow a curved trajectory through an annular cuff of the attachment ring and through the underlying tissue. The tips loop back out of the tissue and to a location where they are later trapped or clamped by the attachment ring. While the tips are trapped or clamped, the applicator tool cinches the clips by pulling rear segments of the clips. Thereafter, the applicator tool disconnects from the attachment ring which remains anchored to the tissue and serves as a coupling for a cannula. The cannula can have movable lock members that secure it to the attachment ring. 1. An assembly for retaining a plurality of clips deployed to connect the assembly to tissue , the assembly comprising:a main body configured to contain a medial segment of each clip;a first device configured to trap a forward segment of each clip; anda second device configured to cinch each clip while the forward segments of the clips are trapped by the first device.2. The assembly of claim 1 , wherein the first device is configured to slide over and then lock onto the main body.3. The assembly of claim 2 , wherein the first device is configured to slide over the main body in a first sliding direction claim 2 , the main body includes a cylindrical wall claim 2 , the first device includes a flexible arm that is configured to slide on the cylindrical wall and engage a groove formed in the cylindrical wall claim 2 , and the first device is prevented from sliding in a second sliding direction claim 2 , which is opposite the first sliding direction claim 2 , when the flexible arm engages the groove.4. The assembly of claim 2 , wherein the first device is a clamping ring moveable relative to the main body claim 2 , and the ...