23-02-2012 дата публикации
Номер: US20120046467A1
Автор:
[Problem] 2. The quaternary ammonium salt compound or pharmaceutically acceptable salt thereof according to claim 1 , wherein R claim 1 , X claim 1 , and Aare any of the following (i) to (iv):{'sup': 2', '1, 'sub': 1-4', '1-8', '1-4, '(i) Rrepresents a single bond, Calkylene substituted on a carbon atom by an oxygen atom, unsubstituted Calkylene, or unsubstituted —O—Calkylene; X represents —O—; Arepresents a single bond or unsubstituted phenylene,'}{'sup': 2', '3', '1, 'sub': 1-4', '2-4', '1-4', '1-4', '6-8, '(ii) Rrepresents unsubstituted Calkylene, unsubstituted Calkenylene, or unsubstituted —O—Calkylene; X represents —CONR—; Arepresents a single bond, unsubstituted phenylene, unsubstituted Calkylene-unsubstituted phenylene, or unsubstituted Ccycloalkylene,'}{'sup': 2', '3', '3', '1, 'sub': 1-4', '2, '(iii) Rrepresents unsubstituted Calkylene; X represents —NRCO— or —NRCO—CH—O; Arepresents unsubstituted phenylene, and'}{'sup': 2', '1, '(iv) R, X, and Arepresent a single bond.'}3. The quaternary ammonium salt compound or pharmaceutically acceptable salt thereof according to claim 1 , wherein R claim 1 , X claim 1 , A claim 1 , and Rare any of the following (v) to (xviii):{'sup': 2', '1', '4, 'sub': '1-10', '(v) Rrepresents a single bond; X represents —O—; Arepresents a single bond; Rrepresents unsubstituted Calkylene,'}{'sup': 2', '1', '4, 'sub': 1-8', '1-8', '1-10, '(vi) Rrepresents unsubstituted Calkylene or Calkylene substituted on a carbon atom by an oxygen atom; X represents —O—; Arepresents a single bond; Rrepresents unsubstituted Calkylene,'}{'sup': 2', '1', '4, 'sub': 1-8', '1-4, '(vii) Rrepresents unsubstituted Calkylene; X represents —O—; Arepresents unsubstituted phenylene-; Rrepresents unsubstituted Calkylene,'}{'sup': 2', '1', '4, 'sub': 1-4', '1-4, '(viii) Rrepresents —O-unsubstituted Calkylene; X represents —O—; Arepresents unsubstituted phenylene; Rrepresents unsubstituted Calkylene,'}{'sup': 2', '3', '1', '4, 'sub': 1-4', '1-8, '(ix) Rrepresents ...
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