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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 4723. Отображено 100.
05-01-2012 дата публикации

Process for preparing isocyanates

Номер: US20120004445A1
Автор: Carsten Knoesche, Torsten Mattke, Vanessa Simone Lehr
Принадлежит: BASF SE

The invention relates to a process for preparing isocyanates by reacting the corresponding amines with phosgene, optionally in the presence of an inert medium, in which phosgene and amine are first mixed and converted to the isocyanate in a reactor, and in which a reaction gas which comprises isocyanate and hydrogen chloride leaving the reactor is cooled in a quench by adding a liquid quench medium to form a mixture of reaction gas and quench medium as the product stream. The walls of the quench are essentially completely wetted with a liquid.

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Номер записи: 1
19-01-2012 дата публикации

Process for preparing isocyanates

Номер: US20120016154A1
Автор: Carsten Knoesche, Torsten Mattke
Принадлежит: BASF SE

The invention relates to a process for preparing isocyanates by reacting the corresponding amines with phosgene in the gas phase, if appropriate in the presence of an inert medium, in which the amine and the phosgene are first mixed and converted to the isocyanate in a reactor, and in which a reaction gas which comprises isocyanate and hydrogen chloride and leaves the reactor is cooled in a quench space of a quench by adding a quench medium. The quench medium on addition to the quench space has a temperature above the condensation temperature or the desublimation temperature of the reaction gas.

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Номер записи: 2
23-02-2012 дата публикации

Method for producing color-stable mda and mdi

Номер: US20120046497A1
Автор: Daniel Breuninger, Eckhard Stroefer, Heiner Schelling, Kai Thiele, Markus Kraemer, Michael Zoellinger, Peter Van Den Abeel, Robert Reinhardt
Принадлежит: BASF SE

The invention relates to a process for preparing methylenediphenyldiamine (MDA) by reacting formaldehyde and aniline in the presence of an acidic catalyst, wherein the oxygen content in the process for preparing MDA is <10 000 ppm, based on all compounds present in the process. The invention further relates to the phosgenation of MDA to methylenediphenyl diisocyanate (MDI).

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Номер записи: 3
26-04-2012 дата публикации

Process for the production of isocyanates, preferably diisocyanates and polyisocyanates with solvent recirculation

Номер: US20120101299A1
Автор: Eckhard Stroefer, Heiner Schelling, Jon S. Speier, Kai Thiele, Matthias Eiermann, Michael Bock, Ulrich Penzel
Принадлежит: BASF SE

The present invention relates to a process for the production of isocyanates, preferably diisocyanates and polyisocyanates of the diphenylmethane series (MDI), by reacting an amine with phosgene in the liquid phase or in the gas phase to form the corresponding isocyanates, subsequent removal of the solvent in at least two steps to obtain at least two solvent streams, individual treatment of the at least two solvent streams, and re-circulation of at least a portion of the solvent streams.

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Номер записи: 4
17-05-2012 дата публикации

Process for preparing methylenedi(phenyl isocyanate)

Номер: US20120123151A1
Автор: Heiner Schelling, Kai Thiele, Michael Bock
Принадлежит: BASF SE

The invention relates to a process for preparing methylenedi(phenyl isocyanate), which comprises (a) the phosgenation of two-ring and/or multiring methylenedi(phenylamine), (b) the fractionation of the crude methylenedi(phenyl isocyanate) obtained to give two-ring and multiring isomers, (c) the purification and/or fractionation of the resulting mixture of two-ring isomers of methylenedi(phenyl isocyanate) and (d) the storage of the mixtures obtained in step (c) or in step (b), wherein part of the stored mixtures is reused by means of recirculation in at least one of steps (b) or (c).

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Номер записи: 5
13-12-2012 дата публикации

Strength-improving agent for production of polyurethane foam

Номер: US20120316255A1
Автор: Koji Kabu, Shogo Sugahara, Tomohisa Hirano, Yasuhiro Shindo
Принадлежит: Sanyo Chemical Industries Ltd

Provided is a strength-improving agent for the production of polyurethane foam, said agent enabling the production of a polyurethane foam having high tensile strength, tear strength and compressive strength. A strength-improving agent (A) for the production of polyurethane foam, represented by general formula (I) [wherein each R1 is a residue derived from an active-hydrogen containing compound by the removal of one active hydrogen atom, and multiple R1s may be the same or different; Y is a residue derived from an at least trivalent aromatic polycarboxylic acid (C) by the removal of the carboxyl groups; the aromatic ring of Y is composed of carbon atoms; the substituents on the aromatic ring maybe hydrogen or other groups, with the proviso that at least one of the substituents is hydrogen; a is an integer satisfying the relationship: 2≦a≦[(the number of substituents on the aromatic ring)−2]; Z is a residue derived from an at least m-valent active-hydrogen containing compound by the removal of m active hydrogen atoms; some R1s and Z may be the same, with the proviso that at least one R1 is different from Z; and m is an integer of 1 to 10].

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Номер записи: 6
28-03-2013 дата публикации

METHOD FOR PRODUCING CARBAMATE, METHOD FOR PRODUCING ISOCYANATE, CARBAMATE PRODUCTION SYSTEM, AND ISOCYANATE PRODUCTION SYSTEM

Номер: US20130079546A1
Автор: Fukuda Takeshi, Kato Satoshi, NAKANO Tetsuya, SASAKI Masaaki, TAKAMATSU Koji
Принадлежит: MITSUI CHEMICALS, INC

A method for producing carbamate including a urea production step; a carbamate-forming step: an ammonia separation step of absorbing the gas with water in the presence of carbonate to produce a gas absorption water, and separating ammonia; an aqueous alcohol solution separation step of separating an aqueous alcohol solution from the gas absorption water; an ammonia/carbon dioxide separation step of separating carbon dioxide gas from the aqueous ammonia solution in the gas absorption water from which the aqueous alcohol solution is separated; an aqueous ammonia solution reusing step of mixing the aqueous ammonia solution and carbonate with the water to be used for production of the gas absorption water. 1. A method for producing carbamate , the method comprising the steps of:a urea production step of producing urea by reaction between ammonia and carbon dioxide gas,a carbamate-forming step of producing carbamate by carbamate-forming reaction between amine, the urea, and alcohol, and by-producing a gas containing alcohol, ammonia, and carbon dioxide,an ammonia separation step of absorbing the gas with water to produce a gas absorption water, and separating ammonia,an aqueous alcohol solution separation step of separating an aqueous alcohol solution from the gas absorption water,an ammonia/carbon dioxide separation step of separating carbon dioxide gas from the aqueous ammonia solution in the gas absorption water from which the aqueous alcohol solution is separated, andan aqueous ammonia solution reusing step of using the aqueous ammonia solution along with the water for production of the gas absorption water.2. The method for producing carbamate according to claim 1 , whereinin the ammonia separation step, the gas is absorbed with the water in the presence of carbonate,in the ammonia/carbon dioxide separation step, carbon dioxide gas is separated from the aqueous ammonia solution in the presence of the carbonate, andin the aqueous ammonia solution reusing step, along ...

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Номер записи: 7
04-04-2013 дата публикации

Bridged Macrocyclic Module Compositions

Номер: US20130081999A1
Автор: Freeman William, Kriesel Joshua W., Whiteford Jeffery A.
Принадлежит:

This invention is related to the fields of organic chemistry and nanotechnology. In particular, it relates to materials and methods for the preparation of organic synthons and bridged macrocyclic module components. The bridge macrocyclic module compounds may be used to prepare macrocyclic module compositions such as nanofilms, which may be useful for filtration. 2. The compound of claim 1 , wherein the two or more termini of said bridge moiety are coupled to synthons.3. The compound of claim 1 , wherein the two or more termini of said bridge moiety are coupled to L moieties claim 1 , with the proviso that said L moieties to which the termini are coupled are not direct bonds.4. The compound of claim 1 , wherein n′ is from 4 to 24.5. The compound of claim 1 , wherein n′ is from 6 to 12.98. The compound of - claims 6 , wherein each Qis the same synthon.108. The compound of - claims 6 , wherein each Qis the same synthon.118. The compound of - claims 6 , wherein each Qis the same synthon.158. The compound of - claims 6 , wherein each L between the synthons are the same.168. The compound of - claims 6 , wherein each L between the bridge moiety and the synthons are the same.17. The compound of claim 1 , wherein the synthons are cyclic synthons.18. The compound of claim 1 , wherein the synthons are acyclic synthons.19. The compound of claim 1 , wherein each L is a direct bond.21. The compound of claim 1 , wherein the bridge moiety further comprises a surface attachment group.22. The compound of claim 1 , wherein the bridge moiety further comprises a lipophilic group.23. The compound of claim 1 , wherein the bridge moiety comprises a functional group for coupling the compound to at least a second bridged macrocyclic module compound.24. The compound of claim 1 , wherein the bridge moiety comprises a polymerization center.26. A nanofilm comprising a plurality of bridged macrocyclic modules of .27. The nanofilm of claim 26 , wherein the thickness of the nanofilm composition is ...

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Номер записи: 8
02-05-2013 дата публикации

METHOD FOR PRODUCING TOLUENEDICARBAMATE, METHOD FOR PRODUCING TOLUENEDIISOCYANATE, AND TOLUENEDICARBAMATE

Номер: US20130109881A1
Автор: Kanno Takashi, KOTAKI Yasushi, MURAYAMA Koichi, SASAKI Masaaki, Shimokawatoko Yoshiki, TAKAMATSU Koji, TAKEUCHI Hiroshi
Принадлежит:

A method for producing toluenedicarbamate includes a carbamate production process of producing toluenedicarbamate by reaction between toluenediamine, urea, and/or N-unsubstituted carbamic acid ester, and alcohol; and a benzoyleneurea reduction process of reducing a disubstituted benzoyleneurea and a derivative thereof to 10 mol or less relative to 100 mol of toluenedicarbamate, wherein the disubstituted benzoyleneurea is represented by formula (1) below and has a methyl group and an amino group: 3. The method for producing toluenedicarbamate according to claim 2 , wherein the biuret compound reduction process comprises a first biuret compound reduction process of reducing a first biuret compound represented by formula (2) above where Xand Xare amino groups.4. The method for producing toluenedicarbamate according to claim 3 , further comprising a urea feeding process of feeding urea to the carbamate production process claim 3 ,wherein in the first biuret compound reduction process,when the urea feeding process includes a fluid feeding process, in which urea is melted by heating to be in a fluid state, and to be fed to the carbamate production process, the time after the melting of urea to the completion of its feeding is set to within 2 hours,in the urea feeding process, urea is fed as a slurry to the carbamate production process, orin the urea feeding process, urea is fed in a solid state to the carbamate production process.5. The method for producing toluenedicarbamate according to claim 2 , wherein the biuret compound reduction process comprises a second biuret compound reduction process of reducing a second biuret compound represented by formula (2) above where Xis an amino group or an alkoxy group and Xis an alkoxy group.6. The method for producing toluenedicarbamate according to claim 5 , further comprising an N-unsubstituted carbamic acid ester production process of producing N-unsubstituted carbamic acid ester by reaction between urea and alcohol claim 5 , ...

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Номер записи: 9
23-05-2013 дата публикации

METHOD FOR PRODUCING ISOCYANATES IN THE GAS PHASE

Номер: US20130131377A1
Автор: Bruns Rainer, Loddenkemper Tim, Lorenz Wolfgang, Rausch Andreas Karl, Wershofen Stefan
Принадлежит: Bayer Intellectual Property GmbH

The invention relates to a process for the preparation of isocyanates by reaction of the corresponding amines with phosgene in the gas phase, wherein a diluent containing between 90.0000% by weight and 99.9999% by weight of substances which are inert in the phosgenation process and between 0.0001% by weight and 10.0000% by weight of oxygen is present during the conversion of the amine into the gas phase and the molar ratio of amine to oxygen (O) is ≧1,000:1. 17.-. (canceled)8. Process for the preparation of isocyanates by reaction of the corresponding amines with phosgene in the gas phase , wherein(i) the amine is converted into the gas phase in a vaporization space in the presence of from >0.10% by weight to 25% by weight of a diluent, based on the total weight of diluent and amine;(ii) the gaseous stream obtained from (i) containing amine and diluent is reacted with a gaseous phosgene stream in a reaction space to give the corresponding isocyanate; the diluent employed in step (i) contains between 90.0000% by weight and 99.9999% by weight of substances which are inert in the phosgenation process and between 0.0001% by weight and 10.0000% by weight of oxygen, in each case based on the weight of the diluent, and', {'sub': '2', 'the molar ratio of amine to oxygen (O) in step (i) in the vaporization space is ≧1,000:1.'}], 'characterized in that'}9. Process according to claim 8 , in which in step (i) the amine is converted into the gas phase in the presence of >0.10% by weight to 10% by weight of a diluent which contains between 99.0000% by weight and 99.9950% by weight of substances which are inert in the phosgenation process and between 0.0050% by weight and 1.0000% by weight of oxygen claim 8 , in each case based on the weight of the diluent claim 8 , and wherein the molar ratio of amine to oxygen in the vaporization space is in the range between 1.000:1 and 1 claim 8 ,000 claim 8 ,000:1.10. Process according to claim 8 , in which in step (i) the amine is converted ...

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Номер записи: 10
30-05-2013 дата публикации

PROCESS FOR PREPARING ISOCYANATES BY PHOSGENATION OF THE CORRESPONDING AMINES IN THE GAS PHASE

Номер: US20130137892A1
Автор: Knoesche Carsten, Lehr Vanessa Simone, Mattke Torsten
Принадлежит:

A process for preparing isocyanates by phosgenation of the corresponding amines in a fluidized-bed reactor (R), wherein a gas stream () comprising the phosgene is used as fluidizing gas and keeps an inert solid in suspension and a liquid stream () comprising the amine is fed into the fluidized bed, with the amine vaporizing partially or completely and reacting with the phosgene to give a reaction gas mixture which comprises the corresponding isocyanate and is taken off from the fluidized-bed reactor (R) is proposed. 1. A process for preparing isocyanates by phosgenation of the corresponding amines in a fluidized-bed reactor (R) , wherein{'b': '1', 'a gas stream () comprising the phosgene is used as fluidizing gas and keeps an inert solid in suspension and'}{'b': '2', 'a liquid stream () comprising the amine is fed into the fluidized bed,'}with the amine vaporizing partially or completely and reacting with the phosgene to give a reaction gas mixture which comprises the corresponding isocyanate and is taken off from the fluidized-bed reactor (R).2. The process according to claim 1 , wherein the fluidized-bed reactor (R) is a rotationally symmetrical apparatus having a vertical longitudinal axis.3. The process according to claim 2 , wherein the fluidized-bed reactor (R) is a predominantly cylindrical apparatus.41. The process according to any of to claim 2 , wherein the phosgene-comprising gas stream () comprising from 50 to 100% by weight of phosgene claim 2 , based on the total weight of the phosgene-comprising gas stream claim 2 , preferably from 75 to 100% by weight of phosgene claim 2 , based on the total weight of the phosgene-comprising gas stream claim 2 , more preferably from 90 to 99.9% by weight of phosgene claim 2 , based on the total weight of the phosgene-comprising gas stream claim 2 , is heated to a temperature which is at least 5° C. greater than the vaporization temperature of the amine under the operating conditions (pressure) in the fluidized-bed ...

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Номер записи: 11
06-06-2013 дата публикации

PROCESS FOR THE PREPARATION OF ISOCYANATES

Номер: US20130144081A1
Автор: JAKOBS Eric, Kintrup Jürgen, Lehner Peter, SOPPE Alfred, WERNER Knud
Принадлежит: Bayer Intellectual Property GmbH

The invention relates to a process for the preparation of isocyanates in a system network comprising an isocyanate production plant, a chlorine production plant and a phosgene production plant, in which carbon dioxide formed as a by-product is partially to completely condensed out with the gaseous chlorine formed in the chlorine production plant and enters into the phosgene preparation process and, after the preparation of phosgene, the predominant part of the carbon dioxide formed is thereby sluiced out of the system network in gaseous form. 1. A process for preparing an isocyanate comprising the steps of{'b': 1', '16', '1, '(i) reacting a stream E comprising a primary amine with a phosgene-comprising stream P to form a product stream P, which comprises said isocyanate, hydrogen chloride, unreacted phosgene, and carbon oxides;'}{'b': 1', '2', '3, '(ii) separating the product stream P into a liquid product stream P comprising said isocyanate and a gaseous product stream P comprising hydrogen chloride, unreacted phosgene, and carbon oxides;'}{'b': 3', '4', '5, '(iii) mixing the product stream P with a gaseous product stream P comprising oxygen to form a gaseous mixed stream P;'}{'b': 5', '6, '(iv) oxidizing the gaseous mixed stream P on a catalyst to form a gaseous product stream P comprising hydrogen chloride, carbon dioxide, excess oxygen, chlorine, and water;'}{'b': 6', '7', '8, '(v) partially to completely removing the hydrogen chloride and water from stream P as a stream P comprising hydrochloric acid to form a product stream P depleted in hydrogen chloride and water;'}{'b': 8', '9', '10', '8', '9, '(vi) separating the product stream P into a liquid chlorine-rich product stream P, which comprises chlorine, carbon dioxide, and oxygen, and a gaseous, low-chlorine product stream P, which comprises the residual amount of chlorine from P not contained in P, carbon dioxide, and oxygen;'}{'b': 10', '11', '12, '(vii) dividing the gaseous product stream P into a gaseous ...

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Номер записи: 12
20-06-2013 дата публикации

PROCESS FOR PREPARING POLYURETHANE PREPOLYMERS CONTAINING ISOCYANATE GROUPS

Номер: US20130158291A1
Автор: Buchholz Sigurd, Pirkl Hans-Georg, Schmidt Manfred, Tracht Ursula, Vieler Robert, Weuta Peter
Принадлежит: Bayer Intellectual Property GmbH

The present invention relates to the technical field of isocyanates. The present invention provides a method for preparing NCO prepolymers by reacting a stoichiometric excess of an organic isocyanate with an isocyanate-reactive component, the reaction components being mixed together and the mixture being introduced directly into a storage or transport vessel, where it reacts to completion. 111-. (canceled)12. A method for preparing an isocyanate group-containing prepolymer from an isocyanate group-containing component and an isocyanate group-reactive component , which comprisesmixing continuously the components in a mixing device and immediately after being mixedintroducing continuously the reaction mixture into a storage or transport vessel, where the reaction between the components is completed.13. The method according to claim 12 , wherein the storage or transport vessel has no means of mixing and/or cooling.14. The method according to claim 12 , wherein the transport vessel is the tank of a tanker vehicle.15. The method according to claim 12 , wherein the temperature in the vessel rises less than 60° C.16. The method according to claim 12 , wherein the proportion of isocyanate group-reactive component in the mixture is 0.1 to 10 weight %.17. The method according to claim 12 , wherein the mixing device comprises one or more static mixers.18. The method according to claim 12 , wherein in a first step of a batch production only a first reaction component is initially directed through the mixing device into the vessel claim 12 , before in a second step the second reaction component is directed into the mixing device in addition to the first reaction component claim 12 , where it is mixed with the first reaction component.19. The method according to claim 18 , wherein the reaction component directed through the mixing device in the first step of the batch production is the isocyanate group-containing component and the reaction component directed into the mixing ...

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Номер записи: 13
04-07-2013 дата публикации

PROCESS FOR THE PRODUCTION OF METHYLENE DIPHENYL DIISOCYANATE ISOMER MIXTURES WITH SPECIFIC ISOMER DISTRIBUTIONS AND NEW PRODUCTS DERIVED

Номер: US20130172604A1
Автор: ANDERSON John J., Breed Ashley W., Gillis Paul A., Jansma Gerard I., Jewell Dennis W., Merenov Andrei S., Reed Daniel J.
Принадлежит: Dow Global Technologies LLC

The present invention a process and apparatus for the production of methylene diphenyl diisocyanate (MDI) isomer mixtures with a low 2,2′-MDI isomer content and a high 2,4′-MDI isomer content. The resulting mixtures have an increased reactivity and are acceptable in food grade application due to the reduction in primary aromatic amines formed during the curing process. The process and apparatus also include controlling the amount of 4,4′-MDI, which is the most reactive isomer in the mixture allowing use in a wide variety of applications. 1. A process for the production of a mixture of methylene diphenyl diisocyanate (MDI) isomers , comprising:forming methylene diphenyl diamines and polyamines of the diphenylmethane series by reacting aniline and formaldehyde in the presence of an acid catalyst;phosgenating the methylene diphenyl diamines and polyamines of the diphenylmethane series to produce a mixture of the MDI isomers and polymeric MDI;separating from the mixture of the MDI isomers and the polymeric MDI a first fraction containing at least 98% by weight of the MDI isomers comprising at least 52% by weight of 2,4′-MDI and 2,2′-MDI based on the total weight of the first fraction; andseparating from the first fraction a second fraction containing at least 99% by weight of the MDI isomers comprising at least 52% by weight of 2,4′-MDI based on the total weight of the second fraction.2. The process of claim 1 , wherein the first fraction includes a content of 4 claim 1 ,4′-MDI of from 5% to 48% by weight claim 1 , a content of 2 claim 1 ,4′-MDI of from 46% to 95% by weight claim 1 , and a content of 2 claim 1 ,2′-MDI of from 0.01% to 20% by weight.3. The process of claim 1 , wherein a third fraction having a content of 4 claim 1 ,4′-MDI of at least 98.5% by weight based on the total weight of the third fraction is removed from the mixture after removal of the first fraction.4. The process of claim 3 , wherein polymeric MDI is separated from the third fraction after ...

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Номер записи: 14
11-07-2013 дата публикации

Method for Producing Carbonyl Compund

Номер: US20130178645A1
Автор: Miyake Nobuhisa, Shinohata Masaaki
Принадлежит: ASAHI KASEI CHEMICALS CORPORATION

A method for producing a carbonyl compound of the present invention comprises a step (X) of reacting a specific compound having a urea bond with a carbonic acid derivative having a carbonyl group (—C(═O)—) under heating at a temperature equal to or higher than the thermal dissociation temperature of the urea bond to obtain the carbonyl compound. 2. The method for producing the carbonyl compound according to claim 1 , wherein the step (X) is carried out in the coexistence of a hydroxy compound.3. The method for producing the carbonyl compound according to claim 1 , wherein the carbonyl compound comprises an N-substituted carbamic acid ester.4. The method for producing the carbonyl compound according to claim 1 , wherein the carbonic acid derivative is urea or an N-unsubstituted carbamic acid ester.5. The method for producing the carbonyl compound according to claim 1 , wherein the carbonic acid derivative is a carbonic acid ester.7. The method for producing the carbonyl compound according to claim 1 , wherein the compound having the urea bond is a polyurethane-urea copolymer.9. The method for producing the carbonyl compound according to claim 8 , wherein the compound having the urea bond is a compound produced from an organic primary amine and a phosgene.10. The method for producing the carbonyl compound according to claim 1 , wherein the step (X) is carried out in a distillation column.11. A method for producing an isocyanate claim 1 , comprising a step of subjecting a carbonyl compound obtained by the production method according to claim 1 , to a pyrolytic reaction to produce the isocyanate.12. The method for producing the carbonyl compound according to claim 1 , whereinthe step (X) is carried out using a distillation column comprising a supply port A, a supply port B, and a discharge port C;the step (X) comprises steps of:supplying raw material ingredients containing the compound having the urea bond, or raw material ingredients containing a precursor of the ...

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Номер записи: 15
18-07-2013 дата публикации

Separation Method and Method for Producing Isocyanate

Номер: US20130184488A1
Автор: Miyake Nobuhisa, Shinohata Masaaki
Принадлежит: ASAHI KASEI CHEMICALS CORPORATION

Disclosed is a method for separating, with a multi-stage distillation column, a mixture containing an active hydrogen-containing compound (A) and a compound (B) that reversibly reacts with the active hydrogen containing compound (A), the method comprising distillation-separating the active hydrogen-containing compound (A) and the compound (B) with the multi-stage distillation column in the presence of an intermediate-boiling-point inactive compound (C) that has a normal boiling point between a normal boiling point of the active hydrogen-containing compound (A) and a normal boiling point of the compound (B) and is chemically inactive for both of the (A) and the compound (B). 1. A method for separating , with a multi-stage distillation column , a mixture containing an active hydrogen-containing compound (A) and 5 a compound (B) that reversibly reacts with the active hydrogen-containing compound (A) , the method comprising:distillation-separating the active hydrogen-containing compound (A) and the compound (B) with the multi-stage distillation column in the presence of an intermediate-boiling-point inactive compound (C) 10 that has a normal boiling point between a normal boiling point of the active hydrogen-containing compound (A) and a normal boiling point of the compound (B) and is chemically inactive for the active hydrogen-containing compound (A) and the compound (B).2. The method according to claim 1 , comprising supplying the mixture to an inactive layer comprising the intermediate-boiling-point inactive compound (C) claim 1 , formed within the multi-stage distillation column.3. The method according to claim 1 , comprising supplying the mixture in a gas state to the multi-stage distillation column.4. The method according to claim 1 , wherein the compound (B) is an isocyanate and/or an isothiocyanate.5. The method according to claim 1 , wherein the active hydrogen-containing compound (A) is at least one compound selected from the group consisting of a hydroxy ...

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Номер записи: 16
15-08-2013 дата публикации

GENERATION OF MIXED DIISOCYANATES BY PHOSGENATION OF SOY BASED METHYL AMINO ESTERS

Номер: US20130209729A1
Автор: Sutterlin William Rusty, Tegen Mark G.
Принадлежит: INVENTURE RENEWABLES, INC.

The present invention relates to an improved composition comprising a blend of diisocyanates of Formula (II) derived from their corresponding dianiino alkyl esters obtained from soy protein source, wherein R is an alkyl and n is 1-4, and methods of making and using such compositions as construction material resin binders, in particular, wood resin binders and/or adhesives. 1. A composition comprising at least two diisocyanates and having a structure as set forth in formula II.2. The composition of claim 1 , wherein the composition comprises at least four diisocyanates.3. The composition of claim 1 , wherein the diisocyanates are selected from the group consisting of alkyl 2 claim 1 ,6-diisocyanatohexanoate claim 1 , alkyl 2 claim 1 ,3-diisocyanatopropanoate claim 1 , alkyl 5 -(3 formylguanidino)-2-isocyanatopentanoate claim 1 , and alkyl 2 claim 1 ,4-diisocyanatobutanoate.4. The composition of claim 1 , wherein the diisocyanates are selected from the group consisting of methyl 2 claim 1 ,6-diisocyanatohexanoate claim 1 , methyl 2 claim 1 ,3-diisocyanatopropanoate claim 1 , methyl 5-(3-formylguanidino)-2-isocyanalopentanoate claim 1 , and methyl 2 claim 1 ,4-diisocyanatobutanoate.5. A product of manufacture or a formulation comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'a composition of , and a silica, a wax, an antifoamer, a lubricant, a plasticizer, a softening agent, a pigment, a biocide, a filler or a combination thereof.'}6. A method of preparing a mixture of at least two diisocyanates comprising reacting a mixture of diamino alkyl esters with a diphosphege or a triphosphege.7. A manufactured material or a product of manufacture comprising a polyurethane claim 1 , wherein the polyurethane comprises a composition of .8. The manufactured material or the product of manufacture of claim 7 , wherein the manufactured material or the product of manufacture is an oriented strand board (OSB) claim 7 , a medium-density fiberboard (MDF) claim 7 , or a ...

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Номер записи: 17
15-08-2013 дата публикации

Method For Making Over-Indexed Thermoplastic Polyurethane Elastomer Precursor And Thermoplastic Polyurethane Elastomer Made From The Precursor

Номер: US20130211034A1
Автор: Chou Chien-Hsin, Ichikawa Yasushi, III Thomas J., Kennedy, Liao Hui-Kai
Принадлежит: Nike, Inc.

A method for making over-indexed thermoplastic polyurethane elastomer precursor. The precursor may be cross-linked. 1. A method for making a dried over-indexed thermoplastic polyurethane elastomer precursor having unreacted isocyanate moieties , the method comprising:combining reactants and reacting them to form an over-indexed thermoplastic polyurethane elastomer precursor,cooling the over-indexed thermoplastic polyurethane elastomer precursor in water to form cooled precursor,pelletizing the cooled precursor to form cooled precursor pellets,drying the cooled precursor pellets to a moisture concentration less than about 800 ppm to form dried over-indexed thermoplastic polyurethane elastomer precursor, andpackaging the dried over-indexed thermoplastic polyurethane elastomer precursor in moisture-resistant packaging under conditions that essentially maintain the moisture content of the dried over-indexed thermoplastic polyurethane elastomer precursor at or below about 800 ppm.2. The method of claim 1 , wherein the drying further comprises partially drying the cooled precursor pellets to a moisture concentration less than about 3 claim 1 ,000 ppm by heating to form partially dried precursor pellets and further drying the partially dried precursor pellets to a moisture concentration less than about 800 ppm in an inert gas flow to form dried over-indexed thermoplastic polyurethane elastomer precursor.3. The method of claim 1 , wherein the cooled precursor pellets are partially dried to a moisture concentration less than about 1 claim 1 ,000 ppm.4. The method of claim 2 , wherein the cooled precursor pellets are partially dried to a moisture concentration less than about 1 claim 2 ,000 ppm.5. The method of claim 1 , wherein the dried over-indexed thermoplastic polyurethane elastomer precursor has a moisture content of 500 ppm.6. The method of claim 5 , wherein the dried over-indexed thermoplastic polyurethane elastomer precursor has a moisture content of 300 ppm.7. The ...

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Номер записи: 18
29-08-2013 дата публикации

Producing rigid polymer foams

Номер: US20130225708A1
Автор: Frank Prissok, Michael Harms
Принадлежит: BASF SE

A process for producing a rigid polymer foam comprises reacting components A to C in the presence of component D or an isocyanate-functional prepolymer of components A and B with component C in the presence of component D, the total amount of which is 100 wt %, (A) 35 to 65 wt % of at least one polyisocyanate component A, (B) 5 to 50 wt % of at least one polyol component B, (C) 1 to 59 wt % of at least one polycarboxylic acid component C, and (D) 0.01 to 3 wt % of at least one Lewis base component D, wherein the reaction takes place with release of carbon dioxide.

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Номер записи: 19
05-09-2013 дата публикации

METAL CARBAMATES FORMED FROM TOLYLENEDIAMINES

Номер: US20130231495A1
Автор: Baumann Robert, LEITNER Andreas, SIEGEL Wolfgang
Принадлежит: BASF SE

The invention provides metal carbamates of the general formula (I) 1. (canceled)3. The process according to claim 2 , wherein the alkyl groups R1 and R2 each comprise 2-18 carbon atoms in the chain.4. The process according to claim 2 , wherein the alkyl groups R1 and R2 each comprise 2-7 carbon atoms in the chain.5. The process according to claim 2 , wherein the alkyl groups R1 and R2 are selected from the group consisting of an ethyl claim 2 , propyl claim 2 , butyl claim 2 , 2-methylpropyl claim 2 , 3-methylbutyl claim 2 , n-pentyl claim 2 , 2-methoxyethyl claim 2 , 2-ethoxyethyl and a 2 claim 2 ,2 claim 2 ,2-trifluoroethyl group.6. The process according to claim 2 , wherein the alkyl groups comprise one or more heteroatoms.7. The process according to claim 2 , wherein the alkyl groups comprise one or more oxygen atoms.8. The process according to claim 2 , wherein no heteroatoms are present in R1 and R2.9. The process according to claim 2 , wherein R1 and R2 are identical.10. The process according to claim 2 , wherein R1 and R2 are branched or unbranched.11. The process according to claim 2 , wherein the metal carbamate is solid at room temperature. This application is a divisional of U.S. application Ser. No. 12/920,224 filed Aug. 30, 2010, which is a National Stage of PCT/EP2009/053170 filed Mar. 18, 2009, both of which are incorporated herein by reference. This application also claims the benefit of EP 08152943.0 filed Mar. 18, 2008.The invention provides metal carbamates formed from tolylenediamines and a process for preparing them.Carbamates have been known for a long time. They are prepared typically by reacting aromatic amines with stoichiometric amounts of a base and an organic carbonate.For the preparation of carbamates, a series of processes is known.In these processes, for example, Lewis acids, such as uranium salts (U.S. Pat. No. 3,763,217), aluminum turnings with iodine and Hg promoters (U.S. Pat. No. 4,550,188), zinc salts, iron salts, antimony salts ...

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Номер записи: 20
19-09-2013 дата публикации

PREPARATION OF PET PRECURSOR

Номер: US20130245307A1
Автор: Berg Tom Christian, Nilsen Anne
Принадлежит: GE HEALTHCARE LIMITED

The invention relates to a process for preparation of radiopharmaceutical precursors, and in particular protected amino acid derivatives which are used as precursors for production of radiolabeled amino acids for use in in vivo imaging procedures such as positron emission tomography (PET). Particularly, the invention relates to a process for preparation of a precursor of the [F]-1-amino-3- fluorocyclobutanecarboxylic acid ([F] FACBC) PET agent and particularly to the work-up process of this precursor removing generated salts from the intermediate composition. 2. A process as claimed in wherein X is benzyl.3. A process as claimed in either or wherein R is ethyl.4. A process as claimed in any one of to wherein Y is tent-butyl carbamate (Boc).6. A process as claimed in any one of to wherein in step iii) the amount of water added is about half the amount of ethyl acetate added in step ii).7. A process as claimed in any one of to wherein in step iv) the acid added is HCl.8. A process as claimed in any one of to wherein in step iv) the washing includes washing with pure water claim 1 , with an aqueous solution of sodium hydrogen carbonate and with brine.9. A process as claimed in any one of to further including the steps of concentrating the composition from step iv) under reduced pressure claim 1 , drying and purifying.10. A process as claimed in any one of to wherein the crude reaction product includes a mixture of the syn- and anti-enantiomer of the compound of formula IIIa.12. A process as defined in wherein said leaving group is a halogen substituent or a group represented by —ORwherein Ris either a fluorosulfonic acid substituent or an aromatic sulfonic acid substituent.13. A process as defined in wherein said leaving group is selected from a toluenesulfonic acid substituent claim 12 , a nitrobenzenesulfonic acid substituent claim 12 , a benzenesulfonic acid substituent claim 12 , a trifluoromethanesulfonic acid substituent claim 12 , a fluorosulfonic acid ...

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Номер записи: 21
19-09-2013 дата публикации

PROCESS FOR THE PRODUCTION OF ALIPHATIC ISOCYANATES

Номер: US20130245314A1
Автор: Cameron Paula A., Chen Lao-Jer, Daussin Rory D., Gehrke Joerg-Peter, Jimenez Jorge
Принадлежит: Dow Global Technologies LLC

The present invention is an aliphatic or cycloaliphatic isocyanate obtained form a process comprising the steps of reacting an aliphatic or cycloaliphatic primary amine, with phosgene in the presence of an inert solvent, wherein the initial reaction temperature is between 100 and 130° C. and the temperature is subsequently ramped to 150 to 180° C. during the course of the reaction, the solvent to amine weight ratio is 95:5 to 80:20, the total reaction pressure is maintained between 50 and 350 psig and the amine is rapidly dispersed in the phosgene through injection in a region of high efficiency mixing. 1. An aliphatic or cycloaliphatic isocyanate obtained from a process comprising:reacting an aliphatic or cycloaliphatic primary amine, or the hydrochloride or carbonate salt thereof, with phosgene in the presence of an inert solvent wherein the initial reaction temperature is between 100 and 130° C. and within 60 minutes of reaching said reaction temperature,subsequently increasing the temperature to 150 to 180° C. during the course of the reaction over a time span of about 10 minutes or less,maintaining the solvent to amine weight ratio from 95:5 to 80:20,maintaining the total reaction pressure between 50 and 350 psig anddispersing the amine in the phosgene.2. The aliphatic or cycloaliphatic isocyanate of wherein the amine is dispersed in the phosgene through injection.3. The process of claim 1 , wherein phosgene is used as a co-solvent.4. An aliphatic or cycloaliphatic isocyanate obtained from process comprising:reacting an aliphatic or cycloaliphatic amine, or the hydrochloride or carbonate salt thereof, with phosgene in the presence of an inert solvent wherein the reaction is done in two or more sequential reactors,maintaining reactor temperature from 100 to 130° C.,controlling the solvent to amine weight ration is 95:5 to 80:20, and the total reactor pressure from 50 to 350 psig andproviding a residence time in the first reactor of less than 5 minutes; ...

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Номер записи: 22
28-11-2013 дата публикации

STABILIZED ISOCYANATE GROUP-CONTAINING ETHYLENICALLY UNSATURATED COMPOUND

Номер: US20130317248A1
Автор: NISHIMURA Norihito, YOROZUYA Shinichi
Принадлежит: SHOWA DENKO K.K.

An object of the present invention is to improve the stability of an ethylenically unsaturated compound having an isocyanate group in the molecule by preventing a polymerization of the ethylenically unsaturated compound. The present invention relates to a stabilizing composition for an isocyanate group-containing ethylenically unsaturated compound, comprising: an isocyanate group-containing ethylenically unsaturated compound (A) which comprises one or more isocyanate groups and one or more ethylenically unsaturated groups in the molecule; and a stabilizing agent (B) which is a compound in which at least one of the ethylenically unsaturated groups in the compound (A) is replaced with an alkyl group which may have a substituent. 1. A stabilizing composition for an isocyanate group-containing ethylenically unsaturated compound , comprising:an isocyanate group-containing ethylenically unsaturated compound (A) which comprises one or more isocyanate groups and one or more ethylenically unsaturated groups in the molecule; anda stabilizing agent (B) which is a compound in which at least one of the ethylenically unsaturated groups in the compound (A) is replaced with an alkyl group which may have a substituent.2. The stabilizing composition according to claim 1 , wherein the compound (A) is a compound comprising one or more ethylenically unsaturated groups represented by the following formula (1); and the stabilizing agent (B) is a compound in which at least one of the ethylenically unsaturated groups represented by the formula (1) in the compound (A) is replaced with a structure represented by the following formula (2) or (3):{'br': None, 'sup': 1', '2', '3, '—CR═CRR\u2003\u2003(1)'}{'sup': 1', '3, 'claim-text': {'br': None, 'sup': 4', '5', '6', '7', '8, '—CRR—CRRR\u2003\u2003(2)'}, '(wherein Rto Reach independently represent a hydrogen atom, an alkyl group having 1 to 4 carbon atoms or an aromatic group);'}{'sup': 4', '8, 'claim-text': {'br': None, 'sup': 9', '10', '11, '— ...

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Номер записи: 23
28-11-2013 дата публикации

STABILIZED ISOCYANATE GROUP-CONTAINING ETHYLENICALLY UNSATURATED COMPOUND

Номер: US20130317252A1
Автор: NISHIMURA Norihito, OHNO Katsutoshi, YOROZUYA Shinichi
Принадлежит: SHOWA DENKO K.K.

An object of the present invention is to improve the stability of an ethylenically unsaturated compound having an isocyanate group in the molecule by preventing a polymerization, a multimerization reaction and a discoloration reaction of the ethylenically unsaturated compound. The present invention relates to a stabilizing composition for an isocyanate group-containing ethylenically unsaturated compound, comprising: an isocyanate group-containing ethylenically unsaturated compound (A) which comprises one or more isocyanate groups and one or more ethylenically unsaturated groups in the molecule; and a stabilizing agent (B) which is a compound in which at least one of the ethylenically unsaturated groups in the compound (A) is replaced with an alkyl halide group or an amino alkyl group which may have a substituent. 2. The stabilizing composition according to claim 1 , wherein the compound (A) is a compound comprising one or more ethylenically unsaturated groups represented by the following formula (1); and the stabilizing agent (B) is a compound in which at least one of the ethylenically unsaturated groups represented by the formula (1) in the compound (A) is replaced with a structure represented by the following formula (2) or (3):{'br': None, 'sup': 1', '2', '3, '—CR═CRR\u2003\u2003(1)'}{'sup': 1', '3, 'claim-text': {'br': None, 'sup': 4', '5', '6', '7', '8, '—CRR—CRRR\u2003\u2003(2)'}, '(wherein Rto Reach independently represent a hydrogen atom, an alkyl group having 1 to 4 carbon atoms or an aromatic group);'}{'sup': 4', '8', '4', '8, 'claim-text': {'br': None, 'sup': 9', '10', '11, '—CRRR\u2003\u2003(3)'}, '(wherein Rto Reach independently represent a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, an aromatic group, halogen, an alkylamino group or a dialkylamino group; and at least one of Rto Rrepresents halogen, an alkylamino group or a dialkylamino group);'}{'sup': 9', '11', '9', '11, '(wherein Rto Reach independently represent a hydrogen atom, an ...

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Номер записи: 24
19-12-2013 дата публикации

Pentamethylenediisocyanate, method for producing pentamethylenediisocyanate, polyisocyanate composition, polyurethane resin, and polyurea resin

Номер: US20130338330A1
Автор: Hiroshi Takeuchi, Kuniaki Sato, Satoshi Yamasaki, Toshihiko Nakagawa
Принадлежит: Mitsui Chemicals Inc

A Pentamethylene diisocyanate is obtained by phosgenating pentamethylenediamine or its salt obtained by a biochemical method, and contains 5 to 400 ppm of a compound represented by the general formula (1) below and a compound represented by the general formula (2) below in total:

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Номер записи: 25
26-12-2013 дата публикации

PROCESS FOR THE PREPARATION OF RETIGABINE

Номер: US20130345465A1
Автор: Fitzgerald Russ N., Millar Alan, Toczko Jennifer Fell
Принадлежит: Glaxo Group Limited

This invention relates to a novel chemical process for the synthesis of 2-ethyoxycarbonylamino-5-(4-fluorobenzylamino)-nitrobenzene and its use in the preparation of 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene (retigabine/ezogabine) and its polymorphic forms thereof. 2. A process as claimed in for the preparation of a compound of formula (I) or a salt thereof claim 1 , which further comprises reaction of 4-fluorobenzaldehyde and 4-amino-2-nitroaniline followed by reduction using standard procedures to produce a compound of formula (II).3. A process for the preparation of retigabine claim 1 , or a salt thereof claim 1 , which comprises the following steps:(i) reacting a compound of formula (II) with diethylcarbonate in the presence of a base to produce a compound of formula (I), or a salt thereof; and(ii) reduction of compound of formula (I) using standard procedures to produce retigabine;(iii) and optionally preparing a salt thereof.4. A process as claimed in for the preparation of retigabine claim 3 , or a salt thereof claim 3 , which further comprises reaction of 4-fluorobenzaldehyde and 4-amino-2-nitroaniline followed by reduction using standard procedures to produce a compound of formula (II).5. A process as claimed in wherein the base is selected from sodium ethoxide claim 1 , sodium hydride claim 1 , potassium tert-butoxide claim 1 , n-butyl lithium claim 1 , potassium hexamethyldisilylazide (KHMDS) claim 1 , cesium carbonate claim 1 , potassium hydroxide claim 1 , sodium pentoxide claim 1 , sodium tert-butoxide claim 1 , lithium ethoxide claim 1 , sodium hydroxide claim 1 , potassium ethoxide claim 1 , diisopropyl ethyl amine (DIPEA) claim 1 , 1 claim 1 ,8-diazabicylco[5.4.0]undec-7-ene (DBU) claim 1 , 1 claim 1 ,4-diazabicyclo[2.2.2]octane (DABCO) or lithium tert-butoxide.6. A process as claimed in wherein the base is sodium ethoxide.7. A process as claimed in wherein the base is present in range of 1.8 to 2.2 molar equivalents.8. A process ...

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Номер записи: 26
09-01-2014 дата публикации

IMAGING AGENTS

Номер: US20140010762A1
Автор: Charlton Michael Hugh, Davies Stephen John, Drummond Alan Hastings, Moffat David Festus Charles
Принадлежит: Chroma Therapeutics Ltd

An imaging agent for cells which produces an intracellular imaging signal proportional to the amount of hCE-1 in the cells independently of the amount of hCE-2 and/or hCE-3 in the cells, said imaging agent being a covalent conjugate of (a) an imaging agent and (b) an alpha mono- or di-substituted amino acid ester, wherein (a) is directly linked to (b), or (a) is indirectly linked to (b) by a linker radical, and wherein said direct or indirect linkage is via the amino group of (b), and wherein the amino group is not directly linked to a carbonyl group, and wherein the said alpha mono- or di-substituted amino acid ester part is selectively hydrolysable to the corresponding carboxylic acid part by the intracellular carboxylesterase enzyme hCE-1 relative to the intracellular enzymes hCE-2 or hCE-3. 1. An imaging agent for cells which produces an intracellular imaging signal proportional to the amount of hCE-1 in the cells independently of the amount of hCE-2 and/or hCE-3 in the cells , said imaging agent being a covalent conjugate of (a) an imaging agent and (b) an alpha mono- or di-substituted amino acid ester , wherein(a) is directly linked to (b), or (a) is indirectly linked to (b) by a linker radical, and wherein said direct or indirect linkage is via the amino group of (b), and whereinthe amino group is not directly linked to a carbonyl group, and whereinthe said alpha mono- or di-substituted amino acid ester part is selectively hydrolysable to the corresponding carboxylic acid part by the intracellular carboxylesterase enzyme hCE-1 relative to the intracellular enzymes hCE-2 or hCE-3.3. An imaging agent according to wherein Ris H.4. An imaging agent according to wherein the alpha mono- or di-substituted amino acid ester is indirectly linked to the imaging agent by a radical of formula (IA) wherein: Ris ester group of formula —(C═O)ORwherein Ris{'sub': 8', '9', '10, 'RRRC— wherein'}{'sub': 8', '1', '3', 'a', '1', '3', 'b', '2', '3', 'a', '1', '3', 'b', '11', '11', ...

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Номер записи: 27
13-03-2014 дата публикации

METHOD FOR PRODUCING TOLYLENE DIISOCYANATE

Номер: US20140073811A1
Автор: Fukuda Takeshi, KOSUMI Kazuhiro, SASAKI Masaaki, TAKAMATSU Koji
Принадлежит: MITSUI CHEMICALS, INC

A method for producing tolylene diisocyanate includes: mixing a first diaminotoluene containing 2,4-diaminotoluene and 2,6-diaminotoluene at a first isomer ratio and a second diaminotoluene containing 2,4-diaminotoluene and/or 2,6-diaminotoluene at a second isomer ratio that is different from the first isomer ratio so as to prepare mixed diaminotoluene; producing tolylene dicarbamate by reaction of the mixed diaminotoluene, urea and/or N-unsubstituted carbamic acid ester and alcohol; and thermally decomposing the tolylene dicarbamate. 1. A method for producing tolylene diisocyanate containing 2 ,4-tolylene diisocyanate and 2 ,6-tolylene diisocyanate at a target isomer ratio , the method comprising:mixing a first diaminotoluene containing 2,4-diaminotoluene and 2,6-diaminotoluene at a first isomer ratio and a second diaminotoluene containing 2,4-diaminotoluene and/or 2,6-diaminotoluene at a second isomer ratio that is different from the first isomer ratio so as to prepare mixed diaminotoluene;producing tolylene dicarbamate by reaction of the mixed diaminotoluene, urea and/or N-unsubstituted carbamic acid ester and alcohol; andthermally decomposing the tolylene dicarbamate.2. The method for producing tolylene diisocyanate according to claim 1 ,wherein the first isomer ratio is 2,4-diaminotoluene/2,6-diaminotoluene (molar ratio)=79 to 81/21 to 19,the second isomer ratio is set such that a proportion of 2,4-diaminotoluene is higher than a proportion of 2,4-diaminotoluene in the first isomer ratio, andin the mixing step, the second diaminotoluene is mixed in an amount of 1 to 30 parts by mass per 100 parts by mass of the first diaminotoluene.3. The method for producing tolylene diisocyanate according to claim 1 ,wherein the second diaminotoluene is produced by decomposing isocyanate residues, which are obtained by separating tolylene diisocyanate and alcohol from a decomposition solution resulting from the thermal decomposition reaction of the tolylene dicarbamate in the ...

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Номер записи: 28
27-03-2014 дата публикации

PROCESS FOR PRODUCING ALDEHYDE COMPOUNDS

Номер: US20140088321A1
Автор: Furuya Masayuki, Kakinuma Naoyuki, Kuma Shigetoshi, Sakata Michiharu, Shimakawa Chitoshi, Tanaka Mamoru, Tokunaga Kouichi
Принадлежит: Mitsui Chemicals, Inc.

A process for producing an aldehyde compound of the invention comprising: reacting a compound represented by the following formula (a1) or (a2) with a hydrogen and a carbon monoxide in a presence of a compound containing a metal belonging to Groups 8 to 10 and a phosphorous compound so as to satisfy the following conditions (1) and (2) to synthesize an aldehyde compound; 2. The process for producing aldehyde compounds according to claim 1 ,wherein the compound containing a metal belonging to Groups 8 to 10 is a rhodium compound, a cobalt compound, a ruthenium compound or an iron compound.3. The process for producing aldehyde compounds according to claim 1 ,wherein the compound containing a metal belonging to Groups 8 to 10 is a rhodium compound.5. The process for producing aldehyde compounds according to claim 1 ,wherein the phosphorous compound is a trivalent phosphorous compound.6. The process for producing aldehyde compounds according to claim 1 ,wherein the reacting step is carried out under solventless condition.7. A process for producing amine compounds comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'reacting the aldehyde compound obtained using the process according to with an ammonia, and reacting with a hydrogen in a presence of a catalyst.'}8. A process for producing isocyanate compounds comprising:{'claim-ref': {'@idref': 'CLM-00007', 'claim 7'}, 'reacting the amine compound obtained by the process according to with a carbonylating agent.'}10. The process for producing amine compounds according to claim 9 ,wherein the compound containing a metal belonging to Groups 8 to 10 is a rhodium compound, a cobalt compound, a ruthenium compound or an iron compound.11. The process for producing amine compounds according to claim 9 ,wherein the compound containing a metal belonging to Groups 8 to 10 is a rhodium compound.14. The process for producing isocyanate compounds according to claim 13 ,wherein the compound containing a metal belonging to Groups ...

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Номер записи: 29
06-01-2022 дата публикации

METHOD FOR PREPARING ISOPHORONE DIISOCYANATE

Номер: US20220002235A1
Автор: CUI Xuelei, HE Wei, Li Wenbin, Li Yuan, LIU Degang, SHANG Yonghua, SUN Ye, WANG Jingxu, Yu Yong, Zhao Lei
Принадлежит:

A method for preparing isophorone diisocyanate by (1) reacting isophorone with hydrogen cyanide in the presence of a catalyst to obtain isophorone nitrile; (2) reacting the isophorone nitrile obtained in step (1) with ammonia gas and hydrogen in the presence of a catalyst to obtain isophorone diamine; and (3) subjecting the isophorone diamine to a phosgenation reaction to obtain the isophorone diisocyanate, wherein the content of impurities containing a secondary amine group in the isophorone diamine that undergoes the phosgenation reaction in step (3) is ≤0.5 wt. The method reduces the content of hydrolyzed chlorine in the isophorone diisocyanate product, improves the yellowing resistance of the product, and the harm due to presence of hydrolyzed chlorine in the product is reduced. 1. A method for preparing isophorone diisocyanate , comprising the following steps:(1) reacting isophorone with hydrogen cyanide in the presence of a catalyst to obtain isophorone nitrile;(2) reacting the isophorone nitrile obtained in step (1) with ammonia gas and hydrogen in the presence of a catalyst to obtain isophorone diamine; and(3) subjecting the isophorone diamine to a phosgenation reaction to obtain isophorone diisocyanate,wherein the content of impurities containing a secondary amine group in the isophorone diamine that is subjected to the phosgenation reaction in step (3) is less than or equal to 0.5 wt %.2. The method according to claim 1 , wherein the content of methylamine in the ammonia gas in step (2) is less than or equal to 0.5 wt %.3. The method according to claim 1 , wherein the content of olefins in the hydrogen cyanide in step (1) is less than or equal to 0.3 wt %.4. The method according to claim 3 , wherein the olefins comprise one or more of ethylene claim 3 , propylene claim 3 , butylene claim 3 , butadiene or isobutylene.5. The method according to claim 1 , wherein in step (1) claim 1 , the material molar ratio of hydrogen cyanide claim 1 , isophorone and ...

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Номер записи: 30
03-01-2019 дата публикации

MARKOVNIKOV-SELECTIVE PALLADIUM CATALYST FOR CARBONYLATION OF ALKYNES WITH HETEROARENES

Номер: US20190001316A1
Автор: Beller Matthias, Franke Robert, Jackstell Ralf, Li Haoquan, Liu Jie
Принадлежит: EVONIK DEGUSSA GmbH

Markovnikov-selective palladium catalyst for carbonylation of alkynes with heteroarenes. 2. Use of a compound according to claim 1 ,for catalysing a carbonylation reaction.3. A process comprising the following process steps:a) initially charging an alkyne,{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'b) adding a compound according to and a substance including Pd,'}c) feeding in N-methylpyrrole and CO,d) heating the reaction mixture, with conversion of the alkyne to the product. The invention relates to Markovnikov-selective palladium catalyst for carbonylation of alkynes with heteroarenes.The development of ligands plays a key role and provides significant innovations in homogenous catalysis and organic synthesis. Illustrative examples include polymerizations, organometallic coupling reactions, carbonylations, hydrogenations and metathesis. Although a plethora of nitrogen- and phosphorous-based ligands have been developed over the last decades, their rational design to afford highly active catalyst systems, which can easily be prepared and modified, continues to be an important topic in this area.Among the privileged ligand classes known, especially bi- and multidentate derivatives create highly stable and selective organometallic complexes.The problem addressed by the invention was that of providing a compound which is to have good properties as ligands in palladium catalyst for carbonylation of alkynes and reaches a good result regarding the yield of the carbonylation reaction.The problem is solved by a compound according to claim ,Compound having the structure (1):Additionally claimed is the use of the compound as ligand in a ligand-metal complex for catalysis of a carbonylation reaction.Use of a compound described above in a ligand-metal complex for catalysis of a carbonylation reaction.The process in which the compound is used as ligand in a ligand-metal complex for conversion of an olefin to an aldehyde is likewise claimed.A process comprising the ...

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Номер записи: 31
07-01-2016 дата публикации

POLYMERIC COMPOSITION FOR MANUFACTURING A POLYPHENOL BASED FOAM MATERIAL, AND PROCESS THEREOF

Номер: US20160002387A1
Автор: Basso Maria Cecilia, Giovando Samuele
Принадлежит:

A polymeric composition for manufacturing a polyphenolic based foam material includes isocyanate, an acid catalyst and tannins. The composition has a mixed tannin-furan-isocyanate structure in which the tannins are part of a resin having the function of reactant for the composition, and it is completely free of low-boiling solvents. The amount of isocyanate is substantially greater than 1% by weight of the composition, preferably not less than 10% by weight with respect to the composition. The composition is adapted to obtain foam materials by means of the plants used for manufacturing polyurethane foam materials. 1. A polymeric composition for manufacturing a polyphenol based foam material comprising isocyanate , an acid catalyst and tannins ,characterized in that it has a tannin-furan-isocyanate mixed structure in which the tannins are part of a resin having the function of a reactant for the composition, and in that it is totally free of low-boiling solvents, the amount of isocyanate being substantially greater than 1% by weight with respect to the composition, preferably not less than 10% by weight with respect to the composition.2. The composition according to claim 1 , wherein the amount of isocyanate is not less than 15% by weight with respect to the composition.3. The composition according to claim 1 , wherein said resin having the function of a reactant for the composition claim 1 , is a tannin based polyphenolic resin including at least a substance intended to react with the tannins in the presence of the acid catalyst claim 1 , and at least a substance intended to react with the isocyanate in the presence of the acid catalyst.4. The composition according to claim 1 , wherein the amount of the acid catalyst is not greater than 20% by weight of the composition.5. The composition according to claim 4 , wherein the amount of the acid catalyst is in the range between 4% and 10% by weight of the composition.6. The composition according to claim 1 , wherein the ...

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Номер записи: 32
12-01-2017 дата публикации

Process for Extracting Phosgene

Номер: US20170008771A1
Автор: Carr Robert Henry, Mouazer Rabah, Zeeuw Arend-Jan
Принадлежит:

A process for extracting a phosgene compound, comprising providing a membrane extracting unit comprising at least one extracting cell that comprises at least one membrane contactor module having at least two sides, a gas side and a liquid side; letting an initial gas stream comprising a phosgene compound flow on the gas side of the membrane contactor module; and letting an extractant liquid stream, suitable for dissolving a phosgene compound, flow on the liquid side of the membrane contactor module so that the extractant liquid stream absorbs the phosgene compound from the initial gas stream and provides a second extractant liquid stream enriched with the phosgene compound. 1. A process for extracting a phosgene compound from an initial gas stream , comprising:providing a membrane contactor module comprising a membrane, which membrane has at least two sides, a gas side and a liquid side;letting flow an initial gas stream comprising a phosgene compound on the gas side of the membrane; andletting flow an extractant liquid stream, suitable for dissolving the phosgene compound, on the liquid side of the membrane contactor module so that the extractant liquid stream absorbs the phosgene compound from the initial gas stream and provides a second extractant liquid stream enriched with the phosgene compound.2. The process according to claim 1 , wherein the initial gas stream comprises the phosgene compound and a second gas compound selected from the group consisting of hydrogen chloride claim 1 , carbon monoxide claim 1 , carbon dioxide claim 1 , nitrogen and/or chlorine and any combination thereof;wherein the extractant liquid stream, has a higher solubility capability for the phosgene compound than for the second gas compound; andwherein a second gas stream depleted in the phosgene compound is provided.3. The process according to claim 1 , wherein the phosgene compound is selected from the group consisting of phosgene (COCl) claim 1 , bromochlorophosgene (COBrCl) and ...

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Номер записи: 33
19-01-2017 дата публикации

Two-step and one-pot processes for preparation of aliphatic diisocyanates

Номер: US20170015621A1
Автор: Shenghong A. Dai, Wei Hsing LIN, Yi-Syuan GUO
Принадлежит: Great Eastern Resins Industrial Co Ltd

The present invention relates to using a two-step (thermolysis) or one-pot process to prepare aliphatic diisocyanates from aliphatic diamines and diaryl carbonates. Polyisocyanates can also be prepared from polyamines and diaryl carbonates. The present synthetic processes do not apply phosgene or highly toxic reagents and chloro-solvents during the entire procedure.

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Номер записи: 34
15-01-2015 дата публикации

HIGHLY SEGREGATED JET MIXER FOR PHOSGENATION OF AMINES

Номер: US20150018575A1
Автор: Gillis Paul A., Mukherjee Joydeep, Pereira Paulo
Принадлежит:

Embodiments of the present invention provide a mixing conduit () having at least a cylindrical inner surface or a cylindrical outer surface and increased number of jet openings (). The mixing conduits according to embodiment of the present invention improve mixing rates thus reducing formation of undesired by-products without sacrificing structural integrity. Particularly, embodiments of the present invention provide a static mixer () having a substantially circular mixing conduit () with more than about 22 jet openings. 1. A mixing conduit , comprising:a sidewall surrounding an axis and enclosing an inner volume along the axis, wherein the inner volume has two openings on opposite ends allowing an axial stream to enter and exit the inner volume along the axis, the sidewall has an inner surface facing the inner volume and an outer surface facing an exterior volume, at least one of a cross section of the inner surface and a cross section of the outer surface is circular, a plurality of jet openings are formed through the sidewall in a plane perpendicular to the axis, the plurality of jet openings allow lateral streams to flow from the exterior volume into the inner volume, and the number of the plurality of jet openings is greater than 22.2. The mixing conduit of claim 1 , wherein the number of jet openings is between about 22 and about 50.3. The mixing conduit of claim 1 , wherein the number of the plurality of jet openings is greater than 24.4. The mixing conduit of any one of wherein the cross section of the inner surface is circular and the cross section of the outer surface is non-circular.5. The mixing conduit of any one of claim 1 , wherein the cross section of the outer surface is circular and the cross section of the inner surface is non-circular.6. The mixing conduit of any one of claim 1 , wherein the cross section of the inner surface is circular and the cross section of the outer surface is circular.7. The mixing conduit of claim 1 , further comprising ...

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Номер записи: 35
16-01-2020 дата публикации

LIMONENE-DERIVED DIISOCYANATE COMPOUNDS

Номер: US20200017437A1
Автор: King Scott B., Kobilka Brandon M., Kuczynski Joseph, Wertz Jason T.
Принадлежит:

According to one aspect, a process of forming a diisocyanate compound from limonene is disclosed. The process includes performing an oxidation reaction to form a limonene-ketone from limonene having a ketone group at a first position. The process includes performing a conjugate addition reaction on the limonene-ketone to form a limonene-nitrile having a nitrile group bonded at a second position. The process also includes performing a reductive amination reaction on the limonene-nitrile to form a limonene-diamine by reducing the nitrile group to form a first amine group and converting the ketone group to a second amine group. The process further includes forming the diisocyanate compound by converting the first amine group of the limonene-diamine to a first isocyanate group and the second amine group of the limonene-diamine to a second isocyanate group. 1. A process of forming a diisocyanate compound from limonene , the process comprising:performing an oxidation reaction to form a limonene-ketone from limonene, the limonene-ketone having a ketone group at a first position;performing a conjugate addition reaction on the limonene-ketone to form a limonene-nitrile having a nitrile group bonded at a second position;performing a reductive amination reaction on the limonene-nitrile to form a limonene-diamine by reducing the nitrile group to form a first amine group and converting the ketone group to a second amine group; andforming a diisocyanate compound by converting the first amine group of the limonene-diamine to a first isocyanate group and the second amine group of the limonene-diamine to a second isocyanate group.7. The process of claim 1 , wherein the first amine group is converted to the first isocyanate group and the second amine group is converted to the second isocyanate group via a phosgenation reaction.11. (canceled)14. The process of claim 8 , wherein converting limonene to the limonene-diol includes:forming a limonene-alcohol from limonene, the limonene- ...

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Номер записи: 36
21-01-2021 дата публикации

POLYURETHANE FOAM SYSTEM

Номер: US20210017324A1
Автор: Birch Adrian J., Grassini Stefano Carlo E, Oswald Karja
Принадлежит:

A reactive polyurethane foam-forming composition including (I) an isocyanate-containing material; and (II) a polyol-containing admixture of: (a) at least one autocatalytic polyol; (b) at least one grafted polyol; (c) at least one reactive polyether polyol; (d) at least one reactive catalyst; (e) at least one surfactant; and (f) water; and a process for making the above foam-forming composition. 1. A polyurethane foam-forming reaction mixture composition comprising:(I) an isocyanate-containing material; and (a) at least one autocatalytic polyol;', '(b) at least one grafted polyol;', '(c) at least one reactive polyether polyol', '(d) at least one reactive catalyst;', '(e) at least one surfactant; and', '(f) water;, '(II) a polyol-containing admixture ofwherein the foam-forming reaction mixture composition when reacted provides a foam having a demolding time of less than or equal to about 20 seconds and a low emissions value meeting the target value defined in VDA 278 (2015).2. The foam-forming composition of claim 1 , wherein the autocatalytic polyol is an amine-initiated claim 1 , autocatalytic polyoxyethylene-capped polyoxypropylene polyol.3. The foam-forming composition of claim 1 , wherein the grafted polyol is the result of in situ polymerization of styrene and/or acrylonitrile in polyoxyethylene polyoxypropylene polyols.4. The foam-forming composition of claim 1 , wherein the reactive polyether polyol is a polyoxyethylene -capped polyoxypropylene polyol.5. The foam-forming composition of claim 1 , wherein the reactive blowing catalyst is >90% N-[2-[2-(dimethylamino)ethoxy]ethyl]-N-methyl-1 claim 1 ,3-propanediamine.6. The foam-forming composition of claim 1 , wherein the surfactant is an organomodified polysiloxane surfactant.7. The foam-forming composition of claim 1 , including one or more of the following components: a diethanolamine crosslinker; a dirnethylarninopropylarnine reactive catalyst; a non-emissive amine catalyst; and an amine gel catalyst.8. The ...

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Номер записи: 37
26-01-2017 дата публикации

SOLVENT REFINING METHOD FOR ISOCYANATE PREPARED BY PHOSGENE METHOD AND DEVICES USED IN SAME

Номер: US20170022152A1
Автор: Chen Bin, Chen Qinglong, Hua Weiqi, Shi Dekai, Shi Qile, Wang Yang, Xu Dan, Yao Yu, Zhang Hongke, Zhao Dongke
Принадлежит: Wanhua Chemical Group Co., Ltd.

A solvent refining method for isocyanate prepared by the phosgene method and multistage absorbing towers used in same. Solvent to be refined which contains water, iron, and/or phosgene, hydrogen chloride and other materials with color is dealt by the present method and multistage absorbing towers, which can effectively prevent a drying agent from absorbing water and hardening, partial overheating in the tower and generating channeling. Meanwhile, the pressure drop is effectively lowered. In addition, the content of water is ≦50 ppm, the content of iron is ≦5 ppm, the content of phosgene and hydrogen chloride is ≦20 ppm, Pt—Co chroma is ≦20 in the refined solvent. Therefore, the refined solvent can be used as the solvent for preparing isocyanate in the phosgene method and remarkably improve an L color of isocyanate. 1. A solvent refining method for isocyanates prepared by the phosgene method , wherein the solvents to be refined is treated with a multistage absorption tower comprising a support packing section at the bottom , a packing absorbing section in the middle and a support packing section on top from bottom to top; the packing absorption section in the middle comprises N absorbing layers , and N is an integer from 3 to 8 , preferably N is an integer from 4 to 6; from the first absorbing layer to the Nth absorbing layer , the layers are arranged from bottom to top; from the first absorbing layer to the (N−1)th absorbing layer , each layer of these layers is composed of an upper liquid distributing device that connects an external feeding pipe and a lower absorbing packing layer , and the absorbing packing layer of every of the absorbing layers is formed by the uniform mixing of desiccants and adsorbents.2. The method according to claim 1 , wherein the weight ratio of the desiccants to the adsorbents of the absorbing packing layer of the first absorbing layer is 1:1-5:1 claim 1 , preferably 2:1-4:1 claim 1 , and the desiccants represent 4-15% of the weight of ...

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Номер записи: 38
25-01-2018 дата публикации

Reactive mesogen and liquid crystal composition including the same

Номер: US20180023000A1
Автор: Ho Lim
Принадлежит: Samsung Display Co Ltd

Provided are a reactive mesogen that may improve display quality of a liquid crystal display, and a liquid crystal composition including the same. The reactive mesogen is represented by the following Formula: where A 1 , A 2 , and A 3 are each independently a substituted or unsubstituted divalent hydrocarbon ring, or a substituted or unsubstituted divalent heterocycle, L 1 and L 2 are each independently a direct linkage, —O—, —S—, —CO—, —COO—, —OCOO—, —O(CH 2 ) k1 —, —S(CH 2 ) k1 —, —O(CF 2 ) k1 —, —S(CF 2 ) k1 —, —(CH 2 ) k1 —, —CF 2 CH 2 —, —(CF 2 ) k1 —, —CH═CH—, —CF═CF—, —C≡C—, —CH═CH—COO—, or —(CH 2 ) k1 —COO—(CH 2 ) k2 —O—, Z 1 and Z 2 are each independently a direct linkage, —O—, —S—, —CO—, —COO—, —OCOO—, —O(CH 2 ) m1 —, —S(CH 2 ) m1 —, —O(CF 2 ) m1 —, —S(CF 2 ) m1 —, —(CH 2 ) m1 —, —CF 2 CH 2 —, —(CF 2 ) m1 —, —CH═CH—, —CF═CF—, —C≡C—, —CH═CH—COO—, —(CH 2 ) m1 —COO—, —(CH 2 ) m1 —COO—(CH 2 ) m2 —O—, —CH—(S p —Pa)—, —CH 2 CH—(S p —Pa)—, or —(CH—(S p —Pa)—CH—(S p —Pa))—, Pa is a polymerizable group, B is an unsubstituted heterocycle, a substituted or unsubstituted crown ether group, or wherein T 1 and T 2 are each independently —OH, —CH 3 , —CF 3 , —CHF 2 , —CH 2 F, —CH 2 Br, —CHBr 2 , —CHCl 2 , or —CH 2 Cl.

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Номер записи: 39
22-01-2015 дата публикации

PROCESS FOR THE PREPARATION OF POLYISOCYANATES AND USE THEREOF

Номер: US20150025268A1
Автор: BRAHM Martin, Richter Frank
Принадлежит:

The invention relates to a process for isocyanate modification which includes reacting a) at least one organic isocyanate having an NCO functionality greater than or equal to 1, b) a catalyst comprising at least one phosphonium salt comprising at least one cycloalkyl substituent bonded directly to a P atom of a phosphonium cation, c) optionally a solvent, and d) optionally additives. The present invention also relates to a catalyst for isocyanate modification comprising at least one phosphonium salt comprising at least one cycloalkyl substituent bonded directly to a P atom of a phosphonium cation. 1. A process for isocyanate modification which comprises reactinga) at least one organic isocyanate having an NCO functionality greater than or equal to 1,b) a catalyst comprising at least one phosphonium salt comprising at least one cycloalkyl substituent bonded directly to a P atom of a phosphonium cation,c) optionally a solvent, andd) optionally additives.3. The process according to claim 2 , wherein Rto Rindependently of one another represent organic radicals selected from the group consisting of C- to C-alkyl which is optionally branched claim 2 , cyclopentyl claim 2 , and cyclohexyl which is optionally substituted claim 2 , and{'sub': 1', '4, 'wherein at least two of the radicals Rto Rrepresent an optionally substituted cyclopentyl, cyclohexyl radical, or combinations thereof which are each bonded directly to the P atom via a ring carbon atom.'}4. The process according to claim 2 , wherein the phosphonium cation of the formula (I) has a counter-ion X wherein X is selected from the group consisting of fluoride (F) and a di- or poly-(hydrogen) fluoride ([F×(HF)] claim 2 , wherein m represents whole or fractional numbers from 0.001 to 20.5. The process according to claim 1 , wherein the at least one organic isocyanate is selected from the group consisting of aliphatic di- or poly-isocyanates claim 1 , cycloaliphatic di- or poly-isocyanates claim 1 , araliphatic di- or ...

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Номер записи: 40
23-01-2020 дата публикации

CLEANING DEVICE FOR GAS FLOWS FROM ISOCYANATE PRODUCTION

Номер: US20200024225A1
Автор: Duerig Dominik, Kobylka Manfred, Merkel Michael, Seidel Bernhard
Принадлежит:

The invention relates to a cleaning device for separating an organic isocyanate produced by the reaction of an organic amine with a stoichiometric excess of phosgene in the gas phase from the gaseous raw product obtained in the reaction, said device comprising a first separating body comprising at least one raw product supply line for a gaseous raw product flow containing at least the isocyanate, hydrogen chloride and non-reacted phosgene, a first liquid supply line for a liquid flow containing at least one quench liquid, and a first liquid discharge line for a liquid flow containing at least part of the quench liquid and part of the isocyanate, a first gas line for transporting a gas flow containing at least hydrogen chloride, evaporated quench liquid and phosgene leading away from the first separating body. The invention is characterized in that at least one addition body for directly introducing at least one cooling fluid for an at least partial condensation and/or absorption of the gas flow that can be guided via the first gas line is associated with the first gas line. 1. A cleaning apparatus for separating an organic isocyanate prepared by reacting an organic amine with a stoichiometric excess of phosgene in the gas phase from the gaseous crude product obtained in the reaction , comprising a first separating unit having at leasta crude product inlet for a gaseous crude product stream containing at least the isocyanate, hydrogen chloride and unconverted phosgene,a first liquid inlet for a liquid stream containing at least a quench liquid anda first liquid outlet for a liquid stream containing at least some of the quench liquid and at least some of the isocyanate,wherein a first gas conduit for conveying a gas stream containing at least hydrogen chloride, evaporated quench liquid and phosgene departs from the first separation unit, andwherein at least one addition unit for direct introduction of at least one cooling fluid for an at least partial condensation and ...

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Номер записи: 41
28-01-2021 дата публикации

METHOD FOR RECOVERING DIISOCYANATES FROM DISTILLATION RESIDUES

Номер: US20210024459A1
Автор: Bellinghausen Rainer, Dunker Ariane, Lang Stefanie, LIESENFELDER Ulrich, Loddenkemper Tim, Merkel Michael, Morawski Joerg, Seekamp Marc
Принадлежит:

The invention relates to a method for recovering monomer diisocyanates, which are solid at room temperature, from a distillation residue, said method comprising the following steps: (i) preparing at least one residue which contains diisocyanates, which are solid at room temperature, and (ii) separating the residue in at least one kneader-dryer, paddle-dryer and/or roller-dryer in the presence of less than 2 wt % bitumen, based on the mass of the residue prepared in step (i), into a gaseous portion, containing monomer diisocyanate that is solid at room temperature, and a brittle residue depleted of diisocyanate, which is solid at room temperature. 1. A process for recovering monomeric , room temperature solid diisocyanates from a distillation residue , comprising the following steps:(i) providing at least one residue containing a room temperature solid diisocyanate, and(ii) separating the residue in at least one selected from the group consisting of a kneader-drier, a paddle drier and a drum drier in the presence of less than 2% by weight of bitumen, based on the mass of the residue provided in step (i), into a gaseous portion containing monomeric, room temperature solid diisocyanate, and a brittle residue depleted of room temperature solid diisocyanate.2. The process as claimed in claim 1 , wherein the kneader-drier claim 1 , paddle drier or drum drier is designed without a cooling zone.3. The process as claimed in claim 1 , wherein the residue is separated in step (ii) in a drum drier.4. The process as claimed in claim 1 , wherein the separation in step (ii) is effected in the presence of ≤1% by weight of bitumen.5. The process as claimed in claim 1 , wherein the temperature in step (ii) is ≥130° C. to ≤270° C.6. The process as claimed in claim 1 , wherein the pressure in step (ii) is ≥1 mbar to ≤1020 mbar.7. The process as claimed in claim 1 , wherein the room temperature solid diisocyanate is selected from the group consisting of naphthalene 1 claim 1 ,5- ...

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Номер записи: 42
24-04-2014 дата публикации

PROCESS FOR PREPARING ISOCYANATES BY PHOSGENATION OF AMINES IN THE LIQUID PHASE

Номер: US20140114087A1
Автор: Hiller Markus, Mattke Torsten, Pallasch Hans-Juergen
Принадлежит: BASF SE

The present invention relates to a process for preparing isocyanates by reacting amines with phosgene in the liquid phase, where phosgene, hydrogen chloride and isocyanates are separated with stripping columns operated at different pressures. 2. The process according to claim 1 , wherein the higher pressure at the top of the separation column compared to the phosgene/hydrogen chloride stripping column is achieved by the overhead stream from the phosgene/hydrogen chloride stripping column or a vapor stream obtained together with a condensate stream by partial condensation of the overhead stream from the phosgene/hydrogen chloride stripping column in a second condenser being compressed in an ejector before being fed to the separation column so as to give a stream which is introduced into the separation column.3. The process according to claim 2 , wherein the overhead stream from the reaction column or the gas phase of the partially condensed overhead stream from the reaction column claim 2 , preferably the gas phase of the partially condensed overhead stream from the reaction column claim 2 , is utilized as driving stream for the ejector.4. The process according to claim 2 , wherein the vapor stream which is obtained in addition to a liquid stream claim 2 , which is fed to the reaction column claim 2 , from the gaseous/liquid reaction mixture from the residence reactor in the downstream separator is utilized as driving stream for the ejector.5. The process according to claim 3 , wherein the condensate stream which is obtained by partial condensation of the overhead stream from the phosgene/hydrogen chloride stripping column in the second condenser is compressed in a further ejector to give a condensate stream which is introduced into the separation column claim 3 , with the further ejector utilizing claim 3 , as driving stream claim 3 , the condensate stream which is obtained in addition to the vapor stream after partial condensation of the overhead stream from the ...

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Номер записи: 43
02-02-2017 дата публикации

Treatment of Neurodegenerative Diseases with Asparagine Endopeptidase (AEP) Inhibitors and Compositions Related Thereto

Номер: US20170029388A1
Автор: Du Yuhong, Fu Haian, Ye Keqiang
Принадлежит:

This disclosure relates to asparagine endopeptidase inhibitors and compositions and uses related thereto. In certain embodiments, the asparagine endopeptidase inhibitors are useful for treating or preventing neurodegenerative diseases and cognitive disorders such as Alzheimer's Disease. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising an asparagine endopeptidase inhibitor and a pharmaceutically acceptable excipient. In certain embodiments, the disclosure relates to methods of treating or preventing a neurodegenerative disease comprising administering an effective amount of pharmaceutical composition a asparagine endopeptidase inhibitor disclosed herein to a subject in need thereof. 2. The compound of claim 1 , wherein R1 is amino.3. The compound of claim 1 , wherein R2 is hydrogen.4. The compound of claim 1 , wherein R3 is hydrogen.5. The compound of claim 1 , wherein R4 is a heterocyclyl.6. The compound of claim 1 , wherein the compound is 7-morpholinobenzo[c][1 claim 1 ,2 claim 1 ,5] oxadiazol-4-amine.7. A pharmaceutical composition comprising a compound of and a pharmaceutically acceptable excipient.8. The pharmaceutical composition of in the form of a pill claim 7 , capsule claim 7 , tablet claim 7 , or saline aqueous buffer.9. The pharmaceutical composition of claim 7 , wherein the pharmaceutically acceptable excipient is selected from a saccharide claim 7 , disaccharide claim 7 , sucrose claim 7 , lactose claim 7 , glucose claim 7 , mannitol claim 7 , sorbitol claim 7 , polysaccharides claim 7 , starch claim 7 , cellulose claim 7 , microcrystalline cellulose claim 7 , cellulose ether claim 7 , hydroxypropyl cellulose (HPC) claim 7 , xylitol claim 7 , sorbitol claim 7 , maltito claim 7 , gelatin claim 7 , polyvinylpyrrolidone (PVP) claim 7 , polyethylene glycol (PEG) claim 7 , hydroxypropyl methylcellulose (HPMC) claim 7 , crosslinked sodium carboxymethyl cellulose claim 7 , dibasic calcium phosphate claim 7 , calcium ...

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Номер записи: 44
02-02-2017 дата публикации

TRANSFER HYDROGENATION OF CYCLOPAMINE ANALOGS

Номер: US20170029433A1
Автор: Austad Brian C., Genov Daniel G., White Brian H.
Принадлежит:

Provided herein is a process for the transfer-hydrogenation of ketone analogs of members of the jervine type of alkaloids, such as cyclopamine. Also provided herein are novel ruthenium transfer-hydrogenation catalysts. 3. The process of wherein the ring carbon atom that is directly attached to the hydroxyl group on the compound of formula (II-AA) has an (S) stereochemical configuration and Ris hydrogen in the β-position.4. The process of claim 1 , wherein the ruthenium transfer-hydrogenation catalyst comprises an amino alcohol ligand.5. The process of claim 4 , wherein the amino alcohol ligand is achiral.7. The process of claim 6 , wherein Rand Rare both —CHand Ris —CHCH.8. The process of claim 1 , wherein the ruthenium transfer-hydrogenation catalyst comprises an optionally substituted benzene ligand.9. The process according to claim 8 , wherein the optionally substituted benzene ligand is selected from benzene claim 8 , mesitylene claim 8 , p-cymene claim 8 , and hexamethylbenzene.10. The process according to claim 9 , wherein the ruthenium transfer-hydrogenation catalyst is generated from (hexamethylbenzene)ruthenium chloride dimer and an achiral amino alcohol.14. The process according to claim 13 , wherein Xis chloro.17. The process of claim 16 , wherein Rand Rare each methyl claim 16 , Ris ethyl claim 16 , each of R claim 16 , R claim 16 , R claim 16 , R claim 16 , R claim 16 , and Ris methyl claim 16 , and Xis Cl.18. The process of claim 1 , wherein the hydrogen donor is an organic alcohol.19. The process of claim 18 , wherein the reducing is carried out in an ether solvent.20. The process of claim 19 , wherein the reducing is carried out at a temperature of about 10° C. to about 40° C.21. The process of claim 19 , wherein the reducing is carried out in the presence of base. This application is a continuation of U.S. patent application Ser. No. 13/232,851, filed Sep. 14, 2011, now allowed, which claims the benefit of U.S. Provisional Patent Application No. 61/ ...

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Номер записи: 45
30-01-2020 дата публикации

Distributor device, in particular for falling film evaporators, and use thereof

Номер: US20200030712A1
Автор: Christian Drumm, Dieter Hoffmann, Friedhelm Steffens
Принадлежит: Covestro Deutschland AG

The present invention relates to a distributor device ( 10000 ) for the even distribution of a fluid ( 10 ) into 2 or more fluid streams each containing gas ( 11 ) and liquid ( 12 ), with a falling film evaporator ( 100000 ), in which the distributor device according to the invention serves to distribute the 2 or more fluid streams onto the heating pipes of the evaporator, and to the use of the distributor device ( 10000 ) according to the invention and in particular the falling film evaporator ( 100000 ) according to the invention in the production and/or preparation of chemical products. The distributor device according to the invention is characterized, in particular, by a swirl breaker ( 600 ) for the gas phase ( 11 ) which arises from separating the fluid ( 10 ) into a gas phase ( 11 ) and a liquid phase ( 12 ) within the distributor device.

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Номер записи: 46
09-02-2017 дата публикации

PROCESS FOR PREPARING ISOCYANATES IN DIALKYL CARBONATES AS SOLVENT

Номер: US20170036997A1
Автор: HEILIG Manfred, Mattke Torsten, NEVEJANS Filip, Schulz Thomas, THIELE Kai
Принадлежит: BASF SE

The invention relates to a process for preparing isocyanates by reacting primary amines with phosgene in a solvent, where the solvent comprises a dialkyl carbonate. 19-. (canceled)10: A process for preparing polymethylenepolyphenyleneisocyanate , the process comprising:reacting polymethylenepolyphenylenepolyamine with phosgene in a solvent, wherein the solvent comprises a dialkyl carbonate as solvent.11: The process according to claim 10 , wherein the dialkyl carbonate is at least one member selected from the group consisting of dimethyl carbonate claim 10 , diethyl carbonate claim 10 , di-n-propyl carbonate claim 10 , and diisopropyl carbonate.12: The process according to claim 10 , wherein the dialkyl carbonate is present in admixture with a further solvent.13: The process according to claim 12 , wherein the further solvent is an aromatic chlorinated hydrocarbon.14: The process according to claim 13 , wherein the aromatic chlorinated hydrocarbon is at least one member selected from the group consisting of monochlorobenzene and o-dichlorobenzene.15: The process according to claim 13 , wherein the solvent comprises from 50 to 100% by weight of diethyl carbonate and from 0 to 50% by weight of the aromatic chlorinated hydrocarbon as further solvent claim 13 , based on the sum of dialkyl carbonate and the further solvent.16: The process according to claim 10 , wherein the reaction is carried out in at least two stages claim 10 , with the first stage being carried out in a mixing device and the second stage being carried out in at least one residence apparatus.17: The process according to claim 16 , wherein the reaction is carried out in at least three stages claim 16 , with the third stage being carried out in at least one materials separation apparatus and the pressure in each successive stage being lower than in the preceding stage. The invention relates to a process for preparing isocyanates by reacting primary amines with phosgene in a solvent.The preparation of ...

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Номер записи: 47
07-02-2019 дата публикации

METAL CATALYST, METHOD OF C-N COUPLING USING THE SAME AND APPLICATIONS OF THE SAME

Номер: US20190039057A1
Автор: Brandt Andrew L., Ghosh Anindya, Parnell Charlette
Принадлежит:

The present disclosure relates to a metal catalyst for C—H bond activation and/or C—N coupling reaction, and a method using the same and application thereof. Specifically, a metal catalyst represented by the following formula: 4. The metal catalyst according to claim 1 , wherein W claim 1 , X claim 1 , and Y are the same.5. The metal catalyst according to claim 1 , wherein M is Ni claim 1 , Pd claim 1 , Fe claim 1 , Co claim 1 , Cr claim 1 , Mn claim 1 , Cu claim 1 , or Pt.6. A method for C—H bond activation and/or C—N coupling reaction comprising using the metal catalyst according to .7. The method according to claim 6 , wherein the C—N coupling reaction forms C—N bonds between a spcarbon and a primary or secondary amine to form substituted or an alkylated amine.8. The method according to claim 7 , wherein the primary or secondary amine is an aliphatic or aromatic amine.9. The method according to claim 7 , wherein spcarbon is an aliphatic and aromatic hydrocarbon.10. The method according to claim 6 , wherein the C—H bond activation and/or C—N coupling reaction is performed under ambient and mild conditions.11. The method according to claim 6 , wherein the C—H bond activation and/or C—N coupling reaction is performed without the presence of an oxidant or a base.12. The method according to claim 6 , wherein the C—N coupling reaction forms C—N bonds between aliphatic amines claim 6 , to form a cyclic amine.13. The method according to claim 6 , wherein the C—N coupling reaction forms C—N bonds between primary amines claim 6 , to obtain an oligomeric compound.14. The method according to claim 6 , wherein the C—H bond activation and/or C—N coupling reaction is performed in presence of an oxidant or a base.15. The method according to claim 14 , the C—H bond activation and/or C—N coupling reaction is performed in presence of an oxidant that is selected from a group consisting of oxygen claim 14 , hydrogen peroxide claim 14 , t-butylhydroperoxide claim 14 , peracetic acid ...

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Номер записи: 48
06-02-2020 дата публикации

METHOD FOR PRODUCING TWO ISOCYANATES

Номер: US20200039925A1
Автор: Hassell William, Hicks Amber, Kelleher Kevin, Lau Wingwah
Принадлежит:

The invention relates to a method for producing two isocyanates by reacting a first amine with phosgene in a stoichiometric excess in the gas phase to produce a first isocyanate, wherein the excess phosgene is subsequently recovered and recirculated back to react with a second amine to produce a second isocyanate. In another embodiment, both fresh and recycled phosgene may be used in reacting each respective amine to produce an isocyanate. The amine streams may be optimized to contain different concentrations of hydrogen chloride, as required for the production of two different isocyanates. 1. A continuous process for preparing a first isocyanate by gas phase phosgenation of a first amine , and a second isocyanate by gas phase phosgenation of a second amine , comprising:(i) reacting the first amine with freshly generated phosgene to obtain a first process product;(ii) treating the first process product with a first solvent at a temperature which is below the boiling point of the first isocyanate to give a gaseous stream (ii-1) containing hydrogen chloride and unreacted phosgene and a liquid stream (ii-2) containing the first solvent and the first isocyanate;(iii) feeding stream (ii-1) to a distillation column (iii) to give a liquid phosgene-containing stream (iii-1) and a gaseous stream (iii-2) containing hydrogen chloride;(iv) introducing stream (iii-1) to a distillation column (iv), from which a gaseous phosgene-containing stream (iv) is taken off at the top;(v) reacting the second amine with an excess of phosgene that comprises gaseous phosgene-containing stream (iv) to obtain a second process product;(vi) treating the second process product with a second solvent at a temperature which is below the boiling point of the second isocyanate to give a gaseous stream (vi-1) containing hydrogen chloride and unreacted phosgene and a liquid stream (vi-2) containing the second solvent and the second isocyanate;(vii) feeding stream (vi-1) to distillation column (iii);(viii) ...

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Номер записи: 49
15-02-2018 дата публикации

SEPARATION OF A PHOSGENE- AND HYDROGEN CHLORIDE-COMPRISING STREAM

Номер: US20180044179A1
Автор: Mattke Torsten, Pallasch Hans-Juergen, SCHELLING Heiner, THIELE Kai
Принадлежит: BASF SE

The invention relates to a method of separating a phosgene- and hydrogen chloride-comprising stream (), wherein said method comprises conveying the hydrogen chloride- and phosgene-comprising stream () into a distillation column (), withdrawing at the bottom of the distillation column () a phosgene-comprising stream () and withdrawing at the top of the column an essentially hydrogen chloride-comprising stream (). At least a portion of the stream () withdrawn at the top is compressed and at least partially condensed and at least a portion of the liquid and compressed essentially hydrogen chloride-comprising stream is decompressed and recycled into the top of distillation column () as reflux. 1. A method of separating a phosgene- and hydrogen chloride-comprising stream comprising:conveying the hydrogen chloride- and phosgene-comprising stream into a distillation column,withdrawing at the bottom of the distillation column a phosgene-comprising stream, andwithdrawing at the top of the distillation column an essentially hydrogen chloride-comprising stream,wherein at least a portion of the stream withdrawn at the top is compressed and at least partially condensed and at least a portion of the liquid and compressed essentially hydrogen chloride-comprising stream is decompressed and recycled into the top of the distillation column as reflux.2. The method according to claim 1 , wherein the stream is withdrawn at the top at a pressure in the range of from 1 to 10 bar and is compressed to a pressure in the range of from 5 to 25 bar before condensation.3. The method according to claim 1 , wherein the distillation column comprises a rectifying section and a stripping section and the phosgene- and hydrogen chloride-comprising stream is supplied as a side feed between the rectifying section and the stripping section.4. The method according to claim 1 , wherein after compression the essentially hydrogen chloride-comprising stream withdrawn from the top is supplied to a rectifying ...

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Номер записи: 50
25-02-2016 дата публикации

Method for producing isocyanate

Номер: US20160052874A1
Автор: Kouji Takeuchi, Masaaki Shinohata, Naoki Fujimoto, Nobuhisa Miyake
Принадлежит: Asahi Kasei Chemicals Corp

A method for producing an isocyanate, comprising: a carbamation step of generating an N-substituted carbamate from an organic primary amine, urea and an organic hydroxy compound according to a carbamation reaction, and then recovering a first gaseous phase component containing the urea and/or a compound having a carbonyl group derived from the urea, the organic hydroxy compound, and ammonia; a condensation step of condensing the first gaseous phase component with a condenser; an isocyanate production step of producing an isocyanate by subjecting the N-substituted carbamate to pyrolysis; an ammonia absorption step of allowing a second gaseous phase component containing ammonia recovered as a gaseous phase component from the condenser as a main component, to be absorbed by absorption water, and generating gas-absorbed water; and an ammonia stripping step of heating the gas-absorbed water to separate ammonia from the gas-absorbed water.

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Номер записи: 51
25-02-2016 дата публикации

METHOD FOR PRODUCING XYLYLENE DIISOCYANATE AND SYSTEM FOR PRODUCING XYLYLENE DIISOCYANATE

Номер: US20160052875A1
Автор: SASAKI Masaaki, SONE Hideki, TAKAMATSU Koji
Принадлежит: Mitsui Chemicals, Inc.

A method for producing xylylene diisocyanate includes a thermal decomposition step of thermally decomposing xylylene dicarbamate; a first separation step of separating, from the thermal decomposition product obtained in the thermal decomposition step, an isocyanate-containing component containing xylylene diisocyanate as a main component and an alcohol-containing component containing alcohol as a main component and containing xylylene diisocyanate as a subcomponent; a second separation step of separating xylylene dicarbamate and alcohol from the alcohol-containing component obtained in the first separation step; and a returning step of returning xylylene dicarbamate obtained in the second separation step to the thermal decomposition step. 1. A method for producing xylylene diisocyanate comprising:a thermal decomposition step of thermally decomposing xylylene dicarbamate, an isocyanate-containing component containing xylylene diisocyanate as a main component, and', 'an alcohol-containing component containing alcohol as a main component and containing xylylene diisocyanate as a subcomponent,, 'a first separation step of separating, from the thermal decomposition product obtained in the thermal decomposition step,'}a second separation step of separating xylylene dicarbamate and alcohol from the alcohol-containing component obtained in the first separation step, anda returning step of returning xylylene dicarbamate obtained in the second separation step to the thermal decomposition step.2. The method for producing xylylene diisocyanate according to claim 1 , wherein the alcohol-containing component has an alcohol content of 90 mass % or more relative to the total amount of the alcohol-containing component.3. A system of producing xylylene diisocyanate comprising:a thermal decomposition unit of thermally decomposing xylylene dicarbamate, an isocyanate-containing component containing xylylene diisocyanate as a main component, and', 'an alcohol-containing component ...

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Номер записи: 52
13-02-2020 дата публикации

POLYOL COMPONENTS AND USE THEREOF FOR THE PRODUCTION OF RIGID POLYURETHANE FOAMS

Номер: US20200048400A1
Автор: Elbing Mark, KLASSEN Johann, Zarbakhsh Sirus
Принадлежит: BASF SE

This invention relates to a polyol component P), to a process for preparing rigid polyurethane foams by using said polyol component P) and also to the rigid polyurethane foams themselves. 17-. (canceled)8. A polyol component P) , comprising:a) at least one polyether polyol A) having an OH number in a range of from 300 to 500 mg KOH/g, comprising units based on mixtures having a functionality in a range of from 5.7 to 6.4 of the monomers ai), aii) and aiii), each selected from the groups consisting of ai) sucrose,aii) monopropylene glycol, diethylene glycol, triethylene glycol, dipropylene glycol, glycerol and mixtures thereof,aiii) solely propylene oxide as alkylene oxide,b) at least one polyether polyol B) having an OH number in a range of from 300 to 500 mg KOH/g, comprising units based on mixtures having a functionality in a range of from 3.0 to 5.0 of the monomers bi) and bii), each selected from the groups consisting of bi) 2,3-, 3,4-, 2,4-, 2,5-, 2,6-tolylenediamine and mixtures thereof,bii) solely propylene oxide as alkylene oxide,c) at least one polyether polyol C) having an OH number in a range of from 100 to 290 mg KOH/g, comprising units based on mixtures having a functionality in a range of from 3.0 to 5.0 or 2.8 to 3.0 of the monomers ci) and cii), each selected from the groups consisting ofci) amines comprising ethylenediamine, 1,3-propylenediamine, 1,3-, 1,4-butylenediamine, 1,2-, 1,3-, 1,4-, 1,5-, 1,6-hexamethylenediamine, phenylenediamines, 2,3-, 3,4-, 2,4-, 2,5-, 2,6-tolylenediamine and 4,4′-, 2,4′-, 2,2′-diaminodiphenylmethane or mixtures thereof, polyols comprising glycerol, trimethylolpropane, monopropylene glycol, diethylene glycol, triethylene glycol, dipropylene glycol (2,2′-oxydi-1-propanol, 1,1′-oxydi-2-propanol, 2-(2-hydroxypropoxy)-1-propanol) and mixtures thereof,cii) ethylene oxide, propylene oxide, butylene oxide and mixtures thereof as alkylene oxides.9. The polyol component P) of claim 8 , comprising:a) at least one polyether polyol ...

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Номер записи: 53
10-03-2016 дата публикации

PROCESS FOR THE PREPARATION OF DI- AND POLYAMINES OF THE DIPHENYLMETHANE SERIES

Номер: US20160068473A1
Автор: Adamson Richard, Becker Karsten, Knauf Thomas, Lorenz Wolfgang, Wershofen Stefan
Принадлежит:

The invention relates to a method for producing diamines and polyamines of the diphenylmethane series, wherein first aniline and formaldehyde are reacted in the absence of an acidic catalyst to form a reaction mixture containing aminal and water and, after the water has been separated, the aminal is reacted by acid catalysis to form a reaction mixture containing diamines and polyamines of the dephenylmethane series, wherein the separation of the water and aminal is supported by the use of a coalescence aid. According to the invention, a filter bed made of coalescence fiber material is used as coalescence aid. 1. A process for the preparation of di- and polyamines of the diphenylmethane series , comprising:a) reacting aniline and formaldehyde in the presence of an acidic catalyst to give a reaction mixture comprising di- and polyamines of the diphenylmethane series,b) neutralizing the reaction mixture comprising di- and polyamines of the diphenylmethane series,c) separating the neutralized reaction mixture comprising di- and polyamines of the diphenylmethane series in a separation container into an organic phase (1) comprising di- and polyamines of the diphenylmethane series and an aqueous phase,d) further purifying the organic phase (1) comprising di- and polyamines of the diphenylmethane series in a washing container with washing liquid,e) freeing the mixture obtained in step d) from aqueous constituents, giving an organic phase (2) comprising di- and polyamines of the diphenylmethane series, andfreeing the organic phase (2) comprising di- and polyamines of the diphenylmethane series distillatively from water and aniline,whereinthe separation off of the aqueous constituents in step e), comprises:e.1) separating the mixture obtained in step (d) in a separating container into an aqueous and an organic phase (2a), and thene.2) passing the organic phase (2a) obtained in step e.1) through a filter bed made of coalescence fiber material and then separating the organic ...

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Номер записи: 54
10-03-2016 дата публикации

PROCESS FOR THE PREPARATION OF DI- AND POLYAMINES FROM THE DIPHENYLMETHANE SERIES

Номер: US20160068474A1
Автор: GRUNER Klaus-Gerd, Knauf Thomas, Torruella Esteve Obis, Wershofen Stefan
Принадлежит:

The present invention provides a process for preparing di- and polyamines from the diphenylmethane series by converting aniline and formaldehyde in the absence of an acid catalyst to give aminal and water, removing the aqueous phase and further processing the organic aminal phase to give the di- and polyamines of the diphenylmethane series, in which use of a coalescence aid in the phase separation of the process product obtained in aminal reaction reduces the proportion of water and hence also of water-soluble impurities in the organic phase containing the aminal. The di- and polyamines of the diphenylmethane series obtained by acid-catalysed rearrangement and workup after further processing of the aminal phase are outstanding suitably for preparation of the corresponding isocyanates. 1. A process for the preparation of di- and polyamines of the diphenylmethane series , comprising:a) converting aniline and formaldehyde in the absence of an acidic catalyst to a reaction mixture comprising aminal and water, where the formaldehyde to be used comprises at most 2.0% by mass of methanol;b) removing water at least in part from the reaction mixture obtained in step a), giving an organic phase comprising the aminal;c) converting the organic aminal-comprising phase obtained in step b), in the presence of an acidic catalyst, to a reaction mixture comprising di- and polyamines of the diphenylmethane series; andd) neutralizing the reaction mixture comprising di- and polyamines of the diphenylmethane series obtained in step c) and then subjecting the reaction mixture to a work-up comprising washing and distillation;whereinin step a) at least one auxiliary reagent from at least one of the groups (i) to (v) or at least one auxiliary reagent from exclusively group (vi) is added in the mass fractions stated in each case, the mass fractions referring to the total mass of all of the feed substances used in step a) including the mass of the auxiliary reagents added:(i) 0.05% by mass to ...

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Номер записи: 55
29-05-2014 дата публикации

Process to separate phosgene and hydrogen chloride from a fluid stream comprising phosgene and hydrogen chloride

Номер: US20140147373A1
Автор: Mouazer Rabah, Scheffer Ramon
Принадлежит: Huntsman International LLC

A process according to the invention is a process to separate an initial fluid stream comprising phosgene and hydrogen chloride in at least a first and a second fluid stream, said first fluid stream being a hydrogen chloride enriched and phosgene depleted gaseous stream, said second fluid stream being a hydrogen chloride depleted and phosgene enriched stream. The separation is performed by feeding said initial fluid stream to a membrane separation unit, said membrane separation unit separating said initial fluid stream in a first and a second fluid stream 1. A process to separate an initial fluid stream comprising phosgene and hydrogen chloride in at least a first and a second fluid stream , said first fluid stream being a hydrogen chloride enriched and phosgene depleted gaseous stream , said second fluid stream being a hydrogen chloride depleted and phosgene enriched stream , wherein the separation is performed by feeding said initial fluid stream to a membrane separation unit , said membrane separation unit separating said initial fluid stream in said first and said second fluid stream.2. The process according to claim 1 , wherein said initial fluid stream is a gaseous stream.3. The process according to claim 2 , wherein said second fluid stream is a gaseous stream.4. The process according to claim 1 , wherein said initial fluid stream is a liquid stream.5. The process according to claim 4 , wherein said second fluid stream is a liquid stream.6. A process for the conversion of an amine to the corresponding isocyanate component by phosgenation of said amine claim 4 , the process comprising the steps ofProviding a reaction mixture comprising an amine and phosgene to a phosgenation reactor;at least partially converting the amine and the phosgene in said reaction mixture into the corresponding isocyanate component and hydrogen chloride, thereby providing a liquid isocyanate stream comprising said isocyanate component, phosgene and hydrogen chloride;removing at least ...

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Номер записи: 56
19-03-2015 дата публикации

PROCESS FOR PREPARING ISOCYANATES

Номер: US20150080600A1
Автор: Knoesche Carsten, Lehr Vanessa Simone, Mattke Torsten, Olbert Gerhard, SCHELLING Heiner
Принадлежит:

The present invention relates to gas phase phosgenation of amines for preparation of isocyanates. In the present invention, phosgene is prepared by reacting chlorine with an excess of carbon monoxide in a gas phase. The obtained phosgene-containing reaction mixture is divided into two streams by a thermal and/or a membrane separating process. The first stream is a low-carbon monoxide stream of no more than 1% by weight of carbon monoxide, based on a total weight of the first stream. The second stream is a carbon monoxide-rich stream of more than 10% by weight of carbon monoxide, based on a total weight of the second stream. The first stream is used as the phosgene-containing reactant stream in the gas phase phosgenation of amines to prepare isocyanates. The second stream can be recycled into the phosgene synthesis. 1. A process for preparing an isocyanate via a gas phase phosgenation of a corresponding amine , the process comprising:reacting carbon monoxide with chlorine with a stoichiometric carbon monoxide excess over chlorine in a gas phase, thereby obtaining a phosgene-comprising reaction mixture;dividing the phosgene-comprising reaction mixture into a low-carbon monoxide stream and a carbon monoxide-rich stream by at least one separating process of a thermal separating process and a membrane separating process, whereinthe low-carbon monoxide stream comprises not more than 1% by weight of carbon monoxide, based on a total weight of the low-carbon monoxide stream, andthe carbon monoxide-rich stream comprises more than 10% by weight of carbon monoxide, based on a total weight of the carbon monoxide-rich stream; andintroducing the low-carbon monoxide stream as a phosgene-comprising reactant stream into the gas phase phosgenation of the corresponding amine, thereby obtaining the isocyanate and hydrogen chloride as a coproduct.2. The process according to claim 1 , wherein in said reacting claim 1 , the stoichiometric excess of carbon monoxide to chlorine in the gas ...

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Номер записи: 57
05-05-2022 дата публикации

METHOD OF PRODUCING CARBONYL COMPOUND AND FLOW TYPE REACTION SYSTEM OF PRODUCING CARBONYL COMPOUND

Номер: US20220135517A1
Автор: Nishio Ryo, WADA Kenji
Принадлежит: FUJIFILM Corporation

There are provided a method of producing a carbonyl compound by a flow type reaction, including introducing a triphosgene solution, a tertiary amine solution, and an active hydrogen-containing compound solution into flow channels different from each other to cause the respective solutions to flow inside the respective flow channels, joining the respective solutions that flow inside the respective flow channels simultaneously or sequentially so that a reaction between phosgene and an active hydrogen-containing compound occurs, and obtaining a carbonyl compound in a joining solution, in which a non-aqueous organic solvent is used as a solvent of each of the respective solutions and a compound having a cyclic structure is used as the tertiary amine; and a flow type reaction system that is suitable for carrying out this production method.

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Номер записи: 58
05-05-2022 дата публикации

POLYETHER POLYOL

Номер: US20220135730A1
Автор: Bonami Lies, Bosman Joris Karel Peter, Mercier Els Elisabeth
Принадлежит:

The present invention relates to a process for providing a homogeneous polyether polyol composition comprising the following steps: Providing a crude polyether polyol mixture comprising polyether polyol and a Group IA or Group IIA metal ion; Neutralisation of said crude polyether polyol mixture by adding a strong acid to said mixture, resulting in a neutralised polyether polyol composition, which comprises said polyether polyol along with a salt of said Group IA or Group IIA metal ion and said strong acid; Providing said homogeneous polyether polyol composition. characterised in that said strong acid is a pentavalent organic phosphorus compound, and in that said salt is a phosphorus-containing compound based organic salt, which is soluble in said polyether polyol composition.

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Номер записи: 59
12-05-2022 дата публикации

METHOD OF PRODUCING CARBONYL COMPOUND AND FLOW TYPE REACTION SYSTEM OF PRODUCING CARBONYL COMPOUND

Номер: US20220144760A1
Автор: Nishio Ryo, WADA Kenji
Принадлежит: FUJIFILM Corporation

There are provided a method of producing a carbonyl compound by a flow type reaction, including introducing a triphosgene solution into a flow channel (I), bringing the triphosgene solution into contact with a solid catalyst immobilized in at least a part of the flow channel (I) to generate a phosgene solution while the triphosgene solution is flowing through the flow channel (I), joining the phosgene solution and an active hydrogen-containing compound solution that flows inside the flow channel (II), which are subsequently allowed to flow downstream inside a reaction flow channel to be reacted in a presence of a tertiary amine, and obtaining a carbonyl compound in a joining solution; and a flow type reaction system that is suitable for carrying out this production method. 1. A method of producing a carbonyl compound by a flow type reaction , comprising:introducing a triphosgene solution into a flow channel (I), bringing the triphosgene solution into contact with a solid catalyst immobilized in at least a part of the flow channel (I) to generate a phosgene solution while the triphosgene solution is flowing through the flow channel (I), joining the phosgene solution and an active hydrogen-containing compound solution that flows inside a flow channel (II), which are subsequently allowed to flow downstream inside a reaction flow channel to be reacted in a presence of a tertiary amine, and obtaining a carbonyl compound in the joining solution.2. The method of producing a carbonyl compound according to claim 1 ,wherein a temperature in the reaction flow channel is set to be lower than a boiling point of a solvent of which the boiling point is lowest among solvents that are used in the reaction.3. The method of producing a carbonyl compound according to claim 1 ,wherein a column filled with the solid catalyst is incorporated in the flow channel (I) to immobilize the solid catalyst in the flow channel (I).4. The method of producing a carbonyl compound according to claim 1 ...

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Номер записи: 60
06-04-2017 дата публикации

PROCESS FOR OPERATING A GAS PHASE PHOSGENATION PLANT

Номер: US20170096389A1
Автор: Bruns Rainer, Knauf Thomas, Lorenz Wolfgang, STEFFENS Friedhelm, Taube Wolfgang
Принадлежит:

This invention relates to a process for operating a gas phase phosgenation plant () to form an isocyanate () by reacting an amine () with phosgene (), in which the gas phase phosgenation plant is shut down by first stopping the amine stream and still maintaining the phosgene stream. After a period of time which corresponds to at least 10 times the residence time of phosgene () in the main parts of the gas phase phosgenation plant () in regular operation, calculated from the time at which the amine inflow has been completely stopped, the feed of phosgene is also stopped. An inert gas stream () is maintained through the amine and phosgene feeding devices and through all the other essential parts of the gas phase phosgenation plant () during the shutdown. 110042124100. A method of operating a gas phase phosgenation plant () for producing an isocyanate () comprising reacting an amine () with phosgene () in a stoichiometric excess in relation to the primary amino groups of the amine () to give the corresponding isocyanate () , in which said gas phase phosgenation plant () comprises at least{'b': 1000', '10', '1', '3, '(i) an apparatus for providing a gaseous phosgene stream (), optionally comprising, as well as phosgene (), an inert substance (),'}{'b': 2000', '20', '2', '3, '(ii) an apparatus for providing a gaseous amine stream (), optionally comprising, as well as amine (), an inert substance (),'}{'b': 3100', '10', '20', '1100', '2100', '1000', '2000, '(iii) a mixing zone () for mixing the streams () and (), the mixing zone being connected by connecting devices (, ) to the apparatus and the apparatus ,'}{'b': 3200', '3100', '10', '20, '(iv) a reaction zone () arranged downstream of the mixing zone () or further conversion of the previously mixed streams () and (),'}{'b': 4000', '3200, '(v) a reaction stopping zone () arranged downstream of the reaction zone () to end the reaction,'}and optionally{'b': 5000', '1', '5100', '5200, '(vi) a workup section () which ...

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Номер записи: 61
26-03-2020 дата публикации

PROCESS FOR PREPARING AN ISOCYANATE

Номер: US20200095194A1
Автор: Arras Jürgen, Dugal Markus, Loddenkemper Tim
Принадлежит:

The industrial scale preparation of isocyanates gives rise to distillation bottom streams that are in need of further workup. These distillation bottom streams still also contain, as well as a distillation residue consisting of compounds that can be evaporated without decomposition only with great difficulty if at all (also referred to as residue for short), proportions of the desired target product (i.e. isocyanate to be prepared). The present invention relates to a process that enables recovery, in an efficient manner, of this proportion of isocyanate to be prepared in a distillation bottom stream which is obtained in the workup of the crude liquid process product which contains the isocyanate to be prepared and is formed in an isocyanate preparation process. More particularly, the present invention relates to a drying step in which the isocyanate to be prepared is recovered to form a solid material that has been largely to completely freed of this isocyanate. This drying step is characterized by a minimum content of compounds containing carbodiimide groups of 15% by mass, preferably 20% by mass, more preferably 30% by mass, based on the total mass of the distillation residue fed to the drying apparatus used, where this minimum content can also be adjusted by an in situ carbodiimidization. 1. A process for preparing an isocyanate by phosgenating the primary amine corresponding to the isocyanate to be prepared to obtain a liquid crude process product comprising isocyanate to be prepared , comprising: the isocyanate to be prepared,', 'optionally low boilers, and', 'distillation residue; and, 'working up said liquid crude process product to obtain a distillation bottom stream consisting ofworking up said distillation bottom stream, said workup comprising:1) optionally pre-concentrating the distillation bottom stream in an evaporator by partially evaporating the isocyanate to be prepared which is present in the distillation bottom stream to obtain a pre-concentrated ...

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Номер записи: 62
13-04-2017 дата публикации

METHOD FOR OPERATING A GAS-PHASE PHOSGENATION PLANT

Номер: US20170101367A1
Автор: Bruns Rainer, Knauf Thomas, Lorenz Wolfgang, STEFFENS Friedhelm, Taube Wolfgang
Принадлежит: Covestro Deutschland AG

This invention relates to a process for operating a gas phase phosgenation plant () to form an isocyanate () by reacting an amine () with phosgene (), in which the gas phase phosgenation plant is started up by first charging the plant with phosgene. At the same time as, or after the first charge of phosgene, the amine supply devices are rendered inert using a hot inert gas stream (). Then, amine is admixed for the first time. In this way and by maintaining a pressure drop in the amine and phosgene devices to the mixing zone, the back mixing of phosgene into the amine-containing reactant stream during start-up is prevented. 1100421100. A method of operating a gas has phosgenation plant () for producing an isocyanate () comprising reacting an amine () with phosgene () , in which said gas phase phosgenation plant () comprises at least{'b': 1000', '10, '(i) an apparatus for providing a gaseous phosgene stream (),'}{'b': 2000', '20, '(ii) apparatus for providing a gaseous amine stream (),'}{'b': 3100', '10', '20', '1100', '2100', '1000', '2000, '(iii) a mixing zone () for mixing the streams () and (), with the mixing zone being connected by connecting devices (, ) to the apparatus and the apparatus ,'}{'b': 3200', '3100', '10', '20, '(iv) a reaction zone () arranged downstream of the mixing zone () for further conversion of the previously mixed streams () and (),'}{'b': 4000', '3200, '(v) a reaction stopping zone () arranged downstream of the reaction zone () to end the reaction,'}and optionally{'b': 5000', '1', '5100', '5200, '(vi) a workup section (), which comprises devices for recovery and recycling of unconverted phosgene (″) () and devices for obtaining the isocyanate prepared in pure form (),'}{'b': '100', 'wherein the gas phase phosgenation plant () is started up by{'b': 10', '1000', '10', '1100', '3100', '3200', '4000', '3100, 'sub': 10', '10', '10', '3100, '(I) providing a gaseous phosgene stream () at a temperature Tof 200° C. to 600° C. with an absolute ...

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Номер записи: 63
13-04-2017 дата публикации

PROCESS FOR PREPARING ISOCYANATES

Номер: US20170101368A1
Автор: Alvarez Herrero Carlos, Bjoerndahl Charles, Ehlers Matthias, Knauf Thomas, Munoz Velasco Francisco, PLATHEN Peter, Rausch Andreas Karl
Принадлежит:

The invention relates to a method for preparing isocyanates by the phosgenation of the corresponding amines in which problems resulting from the formation of deposits in apparatuses of the reaction segment during activation (starting) and deactivation (termination) of the method can be prevented by processing measures, in particular ensuring that there is a surplus of phosgene relative to the phosgenating amine during the critical starting and termination steps of the method. 2. The process of claim 1 , in which an additional delay device is present between the mixing zone and reaction zone.3. The process of claim 1 , in which the reaction zone has a downstream apparatus for cleaving carbamoyl chloride.4. The process of claim 1 , which claim 1 , after step (C) claim 1 , step (D) comprising displacing the phosgene from the reaction section is run claim 1 , which is conducted by at-first ending the supply of phosgene only claim 1 , while continuous supply of inert solvent still continues.5. The process of claim 1 , in which Tis 80° C. to 130° C.6. The process of claim 1 , in which claim 1 , in step (A) (I) claim 1 , a proportion by mass of phosgene of 0.5% to 20% claim 1 , based on the total mass of phosgene and inert solvent is established.7. The process of claim 1 , in which step A (I) is conducted in such a way that claim 1 , at the end of this step claim 1 , at least 50% by volume claim 1 , of the internal volume of the reaction zone available for the reaction of the amine with phosgene in the inert solvent is charged with the mixture of amine claim 1 , phosgene and inert solvent.8. The process of claim 1 , in which claim 1 , in step (C) claim 1 , the supply of phosgene and inert solvent is still continued for a period of time t claim 1 , the period of time tbeing chosen such that the internal volume of the reaction zone available for the reaction of the amine with phosgene in the inert solvent is run through 0.1 time to 10 times by phosgene and inert solvent.9. ...

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Номер записи: 64
19-04-2018 дата публикации

Separation Method and Method for Producing Isocyanate

Номер: US20180105489A1
Автор: Miyake Nobuhisa, Shinohata Masaaki
Принадлежит: ASAHI KASEI KABUSHIKI KAISHA

Disclosed is a method for separating, with a multi-stage distillation column, a mixture containing an active hydrogen-containing compound (A) and a compound (B) that reversibly reacts with the active hydrogen containing compound (A), the method comprising distillation-separating the active hydrogen-containing compound (A) and the compound (B) with the multi-stage distillation column in the presence of an intermediate-boiling-point inactive compound (C) that has a normal boiling point between a normal boiling point of the active hydrogen-containing compound (A) and a normal boiling point of the compound (B) and is chemically inactive for both of the (A) and the compound (B). 1. A method for separating , with a multi-stage distillation column , a mixture containing an active hydrogen-containing compound (A) and 5 a compound (B) that reversibly reacts with the active hydrogen-containing compound (A) , the method comprising:distillation-separating the active hydrogen-containing compound (A) and the compound (B) with the multi-stage distillation column in the presence of an intermediate-boiling-point inactive compound (C) 10 that has a normal boiling point between a normal boiling point of the active hydrogen-containing compound (A) and a normal boiling point of the compound (B) and is chemically inactive for the active hydrogen-containing compound (A) and the compound (B),wherein the normal boiling point of the active hydrogen-containing compound (A) is lower than the normal boiling point of the compound (B).2. The method according to claim 1 , comprising supplying the mixture to an inactive layer comprising the intermediate-boiling-point inactive compound (C) claim 1 , formed within the multi-stage distillation column.3. The method according to claim 1 , comprising supplying the mixture in a gas state to the multi-stage distillation column.4. The method according to claim 1 , wherein the compound (B) is an isocyanate and/or an isothiocyanate.5. The method according to ...

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Номер записи: 65
29-04-2021 дата публикации

ZWITTERION-RUTHENIUM COMPLEX FOR CATALYTIC AEROBIC OXIDATION REACTIONS

Номер: US20210121862A1
Автор: HU Rongbin, KE Zhihai, LAM Ying-Pong, NG Wing-Hin, YEUNG Ying-Yeung
Принадлежит:

Zwitterion ligand metal complexes and methods of aerobic oxidation using a zwitterion ligand metal complex are provided. The zwitterion ligand metal complexes can include a transition metal salt and a zwitterion ligand, which can comprise a non-conjugated amide anion-phosphonium cation, an amide anion-ammonium cation, or an iminium cation. The methods of aerobic oxidation can include combining the zwitterion ligand metal complex with an oxidizable compound and molecular oxygen to allow the isolation of an oxidized compound from the oxidizable compound. 1. A zwitterion ligand metal complex , comprising:a transition metal salt; anda zwitterion ligand,wherein the zwitterion ligand comprises a non-conjugated amide anion-phosphonium cation or an amide anion-iminium cation.2. The zwitterion ligand metal complex according to claim 1 , wherein the amide anion is a sulfonic amide anion.3. The zwitterion ligand metal complex according to claim 2 , wherein the sulfonic amide anion is a tosylate amide anion.4. The zwitterion ligand metal complex according to claim 1 , wherein the iminium cation is the iminium of 4-pyrrolidinopyridine.5. The zwitterion ligand metal complex according to claim 1 , wherein the phosphonium cation is the phosphonium ion of a trialkylphosphine.6. The zwitterion ligand metal complex according to claim 1 , wherein the zwitterion ligand is a ring-opening product of a strained cyclic amide.7. The zwitterion ligand metal complex according to claim 6 , wherein the strained cyclic amide is an aziridine amide.8. The zwitterion ligand metal complex according to claim 7 , wherein the aziridine amide is cyclohexene imine amide.9. The zwitterion ligand metal complex according to claim 6 , wherein the strained cyclic amide is a sulfonic acid amide.10. The zwitterion ligand metal complex according to claim 9 , wherein the sulfonic acid amide is an aromatic sulfonic amide.11. The zwitterion ligand metal complex according to claim 10 , wherein the aromatic sulfonic ...

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Номер записи: 66
02-04-2020 дата публикации

METHOD FOR PREPARING ALIPHATIC ISOCYANATE

Номер: US20200102268A1
Автор: AHN Cho Hee, CHAE Seung Won, Cho Sang Hyun, KIM Jeon Sik, Park Ju Young
Принадлежит:

Provided is a method capable of preparing high-purity aliphatic isocyanate, particularly, xylylene isocyanate in a high yield in a simple manner without an additional separate process, wherein when aliphatic isocyanate is prepared using phosgene, a side-reaction inhibitor capable of inhibiting side-reactions is introduced during phosgenation. 2. The method of claim 1 , wherein Rto Rin Chemical Formula 1 are each independently a Calkyl group claim 1 , X is hydrogen claim 1 , a hydroxyl group claim 1 , or an acetamido group claim 1 , and Y is an oxyl group.3. The method of claim 1 , wherein the compound of Chemical Formula 1 is selected from the group consisting of 2 claim 1 ,2 claim 1 ,6 claim 1 ,6-tetramethylpiperidine 1-oxyl claim 1 , 4-hydroxy-2 claim 1 ,2 claim 1 ,6 claim 1 ,6-tetramethylpiperidine 1-oxyl claim 1 , and 4-acetamido-2 claim 1 ,2 claim 1 ,6 claim 1 ,6-tetramethylpiperidine 1-oxyl.4. The method of claim 1 , wherein the compound of Chemical Formula 1 is used in a molar ratio of 0.05 to 2 with respect to 100 moles of the aliphatic amine or the salt thereof.5. The method of claim 1 , wherein the reacting with phosgene is performed in an organic solvent having a boiling point of 120° C. or higher.6. The method of claim 1 , wherein the reacting with phosgene is performed in an organic solvent selected from the group consisting of an aromatic hydrocarbon-based organic solvent claim 1 , an ester-based organic solvent claim 1 , and a mixture thereof.7. The method of claim 1 , comprising a first step of introducing the aliphatic amine or the salt thereof to a mixture which is prepared by dissolving the compound of Chemical Formula 1 and 50 wt % to 80 wt % of the total phosgene in an organic solvent at a temperature of −15° C. to −10° C.; and a second step of introducing and reacting the remainder of phosgene at 120° C. to 150° C. after completing the introduction of the aliphatic amine or the salt thereof.8. The method of claim 7 , wherein the compound of ...

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Номер записи: 67
10-07-2014 дата публикации

N-Substituted Carbamic Acid Ester Production Method, Isocyanate Production Method Using Such N-Substituted Carbamic Acid Ester, and Composition for Transfer and Storage of N-Substituted Carbamic Acid Ester Comprising N-Substituted Carbamic Acid Ester and Aromatic Hydroxy Compound

Номер: US20140194650A1
Автор: Miyake Nobuhisa, Shinohata Masaaki
Принадлежит: ASAHI KASEI CHEMICALS CORPORATION

The present invention is a method for producing an N-substituted carbamic acid ester derived from an organic amine from an organic amine, a carbonic acid derivative and a hydroxy composition containing one or more types of hydroxy compounds, wherein the organic amine, the carbonic acid derivative and the hydroxy composition are reacted using a urethane production reaction vessel provided with a condenser, a gas containing the hydroxy composition, the compound having the carbonyl group derived from the carbonic acid derivative, and an ammonia formed as a by-product in the reaction, is introduced into the condenser provided in the urethane production reaction vessel, and the hydroxy composition and the compound having the carbonyl group derived from the carbonic acid derivative are condensed, and wherein a stoichiometric ratio of a hydroxy compound contained in the condensed hydroxy composition to the condensed compound having the carbonyl group derived from the carbonic acid derivative is 1 or more, and a ratio of number of carbonyl groups (—C(═O)—) contained in the compound having the carbonyl group derived from the carbonic acid derivative and number of ammonia molecules contained in the ammonia recovered as a gas from the condenser is 1 or less. 141.-. (canceled)44. The method according to claim 42 , wherein the recovered aromatic hydroxy compound is reused.45. The production method according to claim 42 , wherein a residual liquid containing unreacted N-substituted carbamic acid-O-Ar ester recovered from a bottom of the thermal decomposition reaction vessel is again transferred to the thermal decomposition reaction vessel claim 42 , and the N-substituted carbamic acid-O-Ar ester is subjected to a thermal decomposition reaction.46. The production method according to claim 42 , wherein the isocyanate produced in the production method according to contains 1 to 1000 ppm of the aromatic hydroxy compound that composes the aromatic hydroxy composition based on the ...

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Номер записи: 68
18-04-2019 дата публикации

METHOD FOR PRODUCING 1,5-PENTANEDIISOCYANATE IN THE GAS PHASE

Номер: US20190112259A1
Автор: Ehrig Martin, Halpaap Reinhard, Keller-Killewald Manfred, Sanders Josef, Schymura Armin, Wastian Dietmar
Принадлежит:

The invention relates to a method for producing 1,5-pentanediisocyanate (PDI) by reacting 1,5-pentanediamine (PDA) with phosgene in the gas phase. 1. A process for preparing pentane 1 ,5-diisocyanate (PDI) by reacting a stream of pentane-1 ,5-diamine (PDA) with a stream of phosgene in the gas phase , characterized in thata) increasing the temperatures both of the phosgene stream and of the pentane-1,5-diamine (PDA) stream prior to entry into the reactor are in the range of 230-320° C. andb) supplying the pentane-1,5-diamine (PDA) stream and the phosgene stream, and an inert gas stream to the reactor by an annular gap nozzle, with the inert gas stream being supplied through the annular gap,c) mixing the pentane-1,5-diamine (PDA) stream, the phosgene stream, and the inert gas stream after entry into the reactor andd) reacting the amine and the phosgene,wherein the sum total of N-carbamoylpiperidine (C6-Im) and N-carbamoyltetrahydropyridines (C6-Az) is <400 ppm based on the weight of the PDI, excluding solvent.2. The process for preparing pentane 1 claim 1 ,5-diisocyanate (PDI) according to claim 1 , wherein technical grade PDA having a purity of >99% and a water content of <500 ppm is used.3. The process for preparing pentane 1 claim 2 ,5-diisocyanate (PDI) according to claim 2 , wherein the PDA originates from biobased production.4. The process for preparing pentane 1 claim 1 ,5-diisocyanate (PDI) according to claim 1 , wherein the temperature of the PDA in a) is in the range from 270° C. to 310° C.5. The process for preparing pentane 1 claim 1 ,5-diisocyanate (PDI) according to claim 1 , wherein the temperature of the phosgene in a) is in the range from 270° C. to 310° C.6. The process for preparing pentane 1 claim 1 ,5-diisocyanate (PDI) according to claim 1 , wherein the flow rates of gaseous PGA and phosgene are such that the molar phosgene excess based on one amino group is 30% to 300%.7. The process for preparing pentane 1 claim 1 ,5-diisocyanate (PDI) ...

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Номер записи: 69
13-05-2021 дата публикации

Process for Preparing Isocyanates

Номер: US20210139637A1
Автор: Gillis Paul A., Khan Irfan, Klinger Artur
Принадлежит:

A process for preparing an isocyanate product includes providing a phosgene inlet stream and an amine in solvent inlet stream to a phosgenation mixer, the amine in-solvent inlet stream including one or more amines and one or more inert solvents, and during steady state operation compensating for a fouling pressure drop increase by decreasing a pressure drop in the phosgenation mixer over a time period divided into at least a first period of time T and a second period of time T that is subsequent to the first period of time T. During the second period of time T an amine concentration of the one or more amines in the amine-in-solvent stream is higher than during the first period of time T, and during the second period of time T a phosgene-to-amine ratio value in the phosgenation mixer is higher than during the first period of time T 1. A process for preparing an isocyanate product , the process comprising:providing a phosgene inlet stream and an amine-in-solvent inlet stream to a phosgenation mixer, the amine-in-solvent inlet stream including one or more amines and one or more inert solvents; and{'sub': 1', '2', '1', '2', '1', '2', '1, 'during steady state operation compensating for a fouling pressure drop increase by decreasing a pressure drop in the phosgenation mixer over a time period divided into at least a first period of time Tand a second period of time Tthat is subsequent to the first period of time T, during the second period of time Tan amine concentration of the one or more amines in the amine-in-solvent stream is higher than during the first period of time T, and during the second period of time Ta phosgene-to-amine ratio value in the phosgenation mixer is higher than during the first period of time T.'}2. The process as claimed in claim 1 , wherein the amine concentration is increased for the second period of time Tby decreasing a solvent flow rate for the amine-in-solvent inlet stream.3. The process as claimed in claim 1 , wherein the phosgene-to-amine ...

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Номер записи: 70
03-05-2018 дата публикации

INSULATIVE POLYURETHANE RIDGID FOAM BASED ON TDI LIQUID RESIDUE

Номер: US20180118872A1
Автор: WANG Shu Kui, XU Jian Feng
Принадлежит:

Provided herein is an isocyanate composition which comprises a) TDI liquid residue, and b) other isocyanate component, and relates to reaction formulation for preparing polyurethane which comprises: A) the isocyanate composition of the invention, and B) active hydrogen component. Further provided herein is a polyurethane polymer and a polyurethane polymer foam prepared from the reaction formulation of the invention. Also provided herein is a use of the polyurethane rigid foam of the invention in construction and appliance. 1. An insulation of at least one of subterrain pipes and LNG tanks comprising: [ a) TDI liquid residue, and', 'b) other isocyanate component,', 'wherein an amount of TDI liquid residue in the isocyanate composition is at least 3% by weight and up to 18% by weight, based on a total weight of the isocyanate composition, and', 'wherein the other isocyanate component of the isocyanate composition is selected from the group consisting of aromatic, aliphatic, and cycloaliphatic polyisocyanates,, 'A) an isocyanate composition comprising, 'B) active hydrogen component; and', 'C) blowing agent., 'a rigid polyurethane foam prepared from a reaction formulation comprising2. The insulation of at least one of subterrain pipes and LNG tanks of claim 1 , wherein the amount of TDI liquid residue in the isocyanate composition is in a range from 8% by weight to 18% by weight claim 1 , based on the total weight of the isocyanate composition.3. The insulation of at least one of subterrain pipes and LNG tanks of claim 1 , wherein the TDI liquid residue contains from 50 to 90 by weight percent free toluene diisocyanate.4. The insulation of at least one of subterrain pipes and LNG tanks of claim 1 , wherein the TDI liquid residue has viscosity equal to or greater than 500 cps at 25° C. and equal to or less than 5000 cps at 25° C.5. The insulation of at least one of subterrain pipes and LNG tanks of claim 1 , wherein the other isocyanate component is selected from the ...

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Номер записи: 71
07-05-2015 дата публикации

Method for working up distillation residues from isocyanate production

Номер: US20150126769A1
Автор: Friedhelm Steffens, Hartwig Kempkes, Rainer Bellinghausen, Tim Loddenkemper
Принадлежит: BAYER MATERIALSCIENCE AG, Bayer MaterialScience LLC

The present invention relates to a method for working up distillation residues from isocyanate production in which monomeric isocyanate present in distillation residues is recovered by means of a spray-dry method and the overall yield of monomeric isocyanate is thus significantly increased.

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Номер записи: 72
04-05-2017 дата публикации

METHODS AND COMPOSITIONS FOR MAKING AN AMINO ACID TRIISOCYANATE

Номер: US20170121278A1
Автор: Harrington Roger E., Kalpakci Kerem N., Scher David S.
Принадлежит:

A method of making an amino acid triisocyanate is provided, the method comprising reacting an amino acid trihydrochloride with phosgene to form the amino acid triisocyanate. In some embodiments, the amino acid trihydrochloride comprises lysine ester trihydrochloride salt and the amino acid triisocyanate comprises lysine ester triisocyanate. In some embodiments, there is a lysine ester triisocyanate having a purity of at least about 98%, the lysine ester triisocyanate having a structure resulting from reacting lysine ester trihydrochloride salt with phosgene to form the lysine ester triisocyanate. These lysine ester triisocyanates can be used to make biodegradable polyurethanes. 117.-. (canceled)18. A lysine ester triisocyanate having a purity of at least about 98% , the lysine ester triisocyanate having a structure resulting from reacting lysine ester trihydrochloride salt with phosgene to form the lysine ester triisocyanate.19. A lysine ester triisocyanate according to claim 18 , wherein the lysine ester triisocyanate has a purity of at least about 99% to about 99.99%.20. A lysine ester triisocyanate according to claim 18 , wherein the lysine ester triisocyanate is reacted with a polyol or polyamine to form a biodegradable polyurethane or polyurea. Isocyanate is a functional group having the formula R—N═C═O. A molecule which contains more than one isocyanate groups is referred to as a polyisocyanate (diisocyanate, triisocyanate, etc.). Isocyanates are generally highly reactive.Isocyanates are capable of forming polyurethanes or polyureas when reacted with molecules containing one or more hydroxyl functional groups (e.g., alcohol, polyols, etc.) or amino functionality (—NH) such as in polyamines to form polyureas. A typical reaction resulting in the formation of a polyisocyanate with an alcohol to form a polyurethane is shown below:Polyurethanes can be used as implantable material either as implants either preformed and then implanted into the target tissue site or ...

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Номер записи: 73
25-08-2022 дата публикации

Distillation of polyisocyanates

Номер: US20220267500A1
Автор: Anna GROSSE DALDRUP, Christoph Eggert, Markus MEURESCH, Michael Merkel, Monika GROETZNER, Stefan Groth, Stefan Nolte
Принадлежит: Covestro Intellectual Property GmbH and Co KG

The invention relates to a method for producing polyisocyanates having a low monomer content, said method comprising the following steps: (i) modifying at least one monomeric diisocyanate to obtain a mixture containing at least one polyisocyanate and unconverted monomeric diisocyanate, (ii) separating the mixture obtained in step (i) into at least one gaseous stream containing monomeric diisocyanate and a liquid stream depleted of monomeric diisocyanate, (iii) partially condensing the gaseous stream from (ii) in at least one condenser, so that a liquid condensate and an uncondensed vapour stream are obtained, (iv) post-condensing the uncondensed vapour stream obtained in step (iii) in at least one post-condenser, so that a post-condensate and an uncondensed waste gas are obtained, and (v) delivering the uncondensed waste gas from step (iv) to the suction side of a vacuum pump, characterised in that the at least one post-condenser in step (iv) is operated at a post-condenser temperature, and the at least one condenser in step (iii) is operated at a condenser temperature, wherein the post-condenser temperature is lower by ≥1 to ≤168 K than the condenser temperature.

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Номер записи: 74
25-04-2019 дата публикации

Polyurethane foams with agricultural by-products

Номер: US20190119432A1
Автор: Giuseppe Vairo, Matthew A. ROBINSON, Paolo Golini, Swithin P. ADU-PEASAH
Принадлежит: Dow Global Technologies LLC

A method of producing a polyurethane based foam that includes providing a ground crop residue having an average particle size of less than 10 mm and that is prepared by grinding crop residues, providing a polyurethane system that includes an isocyanate component and an isocyanate-reactive component, of which the polyurethane system has an isocyanate index from 70 to 350, forming a modified polyurethane system by adding the ground crop residue to the polyurethane system in a range from 1.0 wt % to 20.0 wt %, based on a total weight of the modified polyurethane system, and forming the polyurethane based foam so as to have an applied density from 30 kg/m3 to 75 kg/m3, according to ASTM D-1622, and to have the ground crop residue embedded within polyurethane polymers that are a reaction product of the isocyanate component and the isocyanate-reactive component of the polyurethane system.

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Номер записи: 75
16-04-2020 дата публикации

ISOCYANATE PRODUCTION METHOD

Номер: US20200115327A1
Автор: ISHII Yusuke, Kosugi Yuji, Miyake Nobuhisa, NAKAOKA Koichi, OHKUBO Atsushi, SAKURAI Yusuke, SASAKI Takeharu, Shinohata Masaaki, TAKAGAKI Kazuhiro, UEMATSU Tsubasa
Принадлежит: ASAHI KASEI KABUSHIKI KAISHA

An isocyanate production method according to the present invention is a method in which an isocyanate is produced by subjecting a carbamate to thermal decomposition, and includes: a step of preparing a mixture liquid containing the carbamate, an inactive solvent and a polyisocyanate compound; a step of conducting a thermal decomposition reaction of the carbamate by continuously introducing the mixture liquid into a thermal decomposition reactor; a step of collecting a low-boiling decomposition product by continuously extracting the low-boiling decomposition product in a gaseous state from the reactor, the low-boiling decomposition product having a boiling point lower than the polyisocyanate compound; and a step of collecting a high-boiling component by continuously extracting, from the reactor, a liquid phase component which is not collected in a gaseous state at the step of collecting the low-boiling decomposition product. 1. An isocyanate production method in which an isocyanate is produced by thermal decomposition of a carbamate , comprising:a step of preparing a mixture liquid comprising the carbamate and a polyisocyanate compound;a step of conducting a thermal decomposition reaction of the carbamate by continuously introducing the mixture liquid into a thermal decomposition reactor:a step of collecting a low-boiling decomposition product by continuously extracting the low-boiling decomposition product in a gaseous state from the thermal decomposition reactor, the low-boiling decomposition product having a standard boiling point lower than the polyisocyanate compound; anda step of collecting a high-boiling component by continuously extracting, from the thermal decomposition reactor, a liquid phase component which is not collected in a gaseous state at the step of collecting the low-boiling decomposition product, as the high-boiling component.2. The isocyanate production method according to claim 1 , wherein the mixture liquid comprises an inactive solvent claim ...

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Номер записи: 76
16-04-2020 дата публикации

CONTINUOUS DILUTION OF POLYISOCYANATES

Номер: US20200115328A1
Автор: GROTH Stefan, MIDOLO Antonio, WU Ruiwen
Принадлежит:

The invention relates to a process for producing a polyisocyanate composition comprising addition of at least one isocyanate-inert solvent to at least one polyisocyanate, characterized in that the addition of the solvent is carried out in one or more stages and at least one of these stages is performed as a continuous dilution. The invention further relates to the polyisocyanate compositions obtainable by the process, to the use of the polyisocyanate compositions, to a two-component system containing the polyisocyanate composition and to composite systems produced with the two-component system. 1. A process for producing a polyisocyanate composition comprising addition of at least one isocyanate-inert solvent to at least one polyisocyanate , wherein the addition of the solvent is carried out in one or more stages and at least one of these stages is performed as a continuous dilution.2. The process as claimed in claim 1 , wherein the polyisocyanate is based on at least one aliphatic claim 1 , cycloaliphatic claim 1 , araliphatic or aromatic diisocyanate.3. The process as claimed in claim 1 , wherein the polyisocyanate is based on tolylene diisocyanate.4. The process as claimed in claim 1 , wherein the addition of the solvent is carried out in at least two stages claim 1 , wherein the first stage is performed as a continuous dilution.5. The process as claimed in claim 1 , wherein a solids content of ≥30% to ≤90% by weight is established in the first stage.6. The process as claimed in claim 4 , wherein a solids content of ≥10% to ≤80% by weight is established in the second stage claim 4 , wherein the solids content established in the first stage is reduced by at least 15% by weight in the second stage.7. The process as claimed in claim 3 , wherein the polyisocyanate is produced from tolylene diisocyanate by(i) reaction of tolylene diisocyanate to form a polyisocyanate and(ii) removal of the unconverted tolylene diisocyanate down to a residual content of monomeric ...

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Номер записи: 77
14-05-2015 дата публикации

Method for producing 1,5-pentamethylenediamine, mutant lysine decarboxylase, method for producing 1,5-pentamethylene diisocyanate and method for producing polyisocyanate composition

Номер: US20150132808A1
Автор: Akiko Natsuji, Daisuke Mochizuki, Tadashi Araki, Tomomi Sakai, Tomonori Hidesaki
Принадлежит: Mitsui Chemicals Inc

A mutant lysine decarboxylase is produced by replacing at least one of the amino-acids in the amino acid sequence shown in sequence ID No. 4 of the sequence listing with another amino-acid.

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Номер записи: 78
01-09-2022 дата публикации

METHOD FOR PRODUCING ISOCYANATE COMPOUND

Номер: US20220274915A1
Автор: MARUYAMA Hiroki, NAGASHIMA Yuta, NITTA Hirohisa
Принадлежит: Sumitomo Chemical Company, Limited

The present specification discloses a method for producing an isocyanate compound. The invention relates to a method for producing the compound represented by formula (2), 2. The method as claimed in claim 1 , wherein the aqueous layer has a concentration of hydrogen chloride of 15% by weight or less.3. The method as claimed in claim 2 , wherein a base is added such that the aqueous layer has a concentration of hydrogen chloride of 15% by weight or less.4. The method as claimed in claim 3 , wherein the base is an alkali metal hydroxide.5. The method as claimed in claim 1 , wherein the phosgenes correspond to phosgene.6. The method as claimed in claim 1 , wherein the compound or salt thereof represented by formula (1) is a hydrochloride salt of the compound represented by formula (1).7. The method as claimed in claim 1 , further comprising a step of separating a mixture of an organic layer containing the compound represented by formula (2) and the aqueous layer obtained by the reaction to obtain the organic layer containing the compound represented by formula (2) claim 1 , and a step of dehydrating the organic layer at 50° C. or lower. This patent application claims priority under the Paris Convention based on Japanese Patent Application No. 2019-156453 (filed on Aug. 29, 2019), which is incorporated herein by reference in its entirety.The present specification discloses a method for producing an isocyanate compound.The compound represented by formula (2)(having a compound name of 3-methyl-2-(methoxymethyl)-1-isocyanatobenzene, hereinafter referred to as compound (2)) is useful as an intermediate for agrochemicals. For example, Patent Document 1 describes in Reference Manufacture Example 18 that the compound represented by formula (2) is produced by stirring a mixture of the compound (1)(having a compound name of 3-methyl-2-(methoxymethyl)aniline, hereinafter referred to as compound (1)), triphosgene, saturated sodium bicarbonate and ethyl acetate under ice-cold ...

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Номер записи: 79
02-05-2019 дата публикации

SEMI-RIGID POLYURETHANE FOAM AND PROCESS TO MAKE

Номер: US20190127542A1
Автор: El-Khatib Ali J.
Принадлежит:

Disclosed is a composition and process for making a water blown semi-rigid polyurethane foam wherein the polyisocyanate side and the polyol side are combined under ambient temperature conditions. Said foams are particularly suited for sound and vibration management, especially in motor vehicles. 2. The process of wherein the B-side further comprises:vii) 2 to 6 wt % of a crosslinker.3. The process of wherein the polymeric MDI blend a) i) has an NCO range of 18 to 25%.4. The process of wherein the first surfactant a) iii) is an organosilicone.5. The process of further comprising iv) 0.2 to 1.5 wt % of a second organosilicone surfactant different from the first organosilicone surfactant.6. The process of wherein the semi-rigid polyurethane foam is used in an automobile noise and vibration-absorbing application. The present invention relates to a composition and process for making semi-rigid polyurethane foam at ambient temperatures. Said foams are particularly suited for sound and vibration management in motor vehicles.Noise and vibration management is a significant issue for vehicle manufacturers, as cabin noise is a major factor in the comfort experience of automotive passengers. Therefore, noise and vibration abatement measures are routinely incorporated into motor vehicles. These abatement measures often utilize polyurethane foams.Generally, there are two types of polyurethane foams: flexible and rigid. In general, flexible foams have open cellular structures and a flexible polyurethane (e.g., uses a low functionality; high molecular weight polyol) which allows them to be elastically deformed. Generally, when making a flexible polyurethane foam, water in the polyol side is used as the blowing agent. The water reacts with the isocyanate producing carbon dioxide that foams the polyurethane as the isocyanate and polyol react.For automotive applications requiring stiffening, reinforcing, and/or NVH (noise, vibration and harshness) abatement in a vehicle, rigid ...

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Номер записи: 80
19-05-2016 дата публикации

MONITORING AND ASSESSING DEACETYLASE ENZYME ACTIVITY

Номер: US20160138077A1
Автор: DIYABALANAGE Himashinie, Hooker Jacob
Принадлежит: The General Hospital Corporation

Disclosed herein are compounds and methods for detecting enzyme activity. In some embodiments, the enzyme is a deacetylase enzyme such as HDAC. The compound of the invention comprises a detectable label, a linker, and an enamide group. The compound can be enzymatically cleaved by the enzyme of interest to produce a nucleophilic fragment that includes the detectable label. Measurement of a signal generated by the detectable label can indicate enzyme activity. The compounds can be used as either in vivo or in vitro enzyme probes. 1. A compound characterized in having a structure: Lab-L-Ena , wherein Lab is a detectable label , L is a linker , and Ena is an enamide group.3. The compound of claim 1 , wherein the detectable label is an imagining agent or a contrast agent.4. The compound of wherein the detectable label is selected from a group consisting of an optical reporter claim 1 , non-metallic isotope claim 1 , a paramagnetic metal ion claim 1 , a ferromagnetic metal claim 1 , echogenic substance (either liquid or gas) claim 1 , a boron neutron absorber claim 1 , a gamma-emitting radioisotope claim 1 , a positron-emitting radioisotope claim 1 , an x-ray absorber claim 1 , fluorescent molecules claim 1 , radioisotopes claim 1 , nucleotide chromophores claim 1 , enzymes claim 1 , enzyme substrates claim 1 , chemiluminescent moieties claim 1 , magnetic particles claim 1 , bioluminescent moieties claim 1 , nucleic acids claim 1 , antibodies claim 1 , and any combinations thereof.5. (canceled)7. The compound of claim 5 , wherein the fluorescent molecule comprises hydroxycoumarin claim 5 , aminocoumarin claim 5 , methoxycoumarin claim 5 , cascade blue claim 5 , pacific blue claim 5 , pacific orange claim 5 , lucifer yellow claim 5 , nitrobenzoxadiazole (NBD) claim 5 , R-phycoerythrin claim 5 , PE-Cy5 conjugates claim 5 , PE-Cy7 conjugates claim 5 , Red 613 claim 5 , PerCP claim 5 , TruRed claim 5 , FluorX claim 5 , Fluorescein claim 5 , BODIPY claim 5 , Cy2 claim 5 , Cy3 ...

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Номер записи: 81
07-08-2014 дата публикации

GOLD-CATALYZED SYNTHESIS OF CARBONATES AND CARBAMATES FROM CARBON MONOXIDE

Номер: US20140221679A1
Автор: Friend Cynthia M., Madix Robert J., Xu Bingjun
Принадлежит: President and Fellows of Harvard College

The invention provides a method for producing organic carbonates via the reaction of alcohols and carbon monoxide with oxygen adsorbed on a metallic gold or gold alloy catalyst. 2. The method of claim 1 , wherein X is O.3. The method of claim 1 , wherein X is NR.4. The method of claim 1 , wherein the source of the adsorbed oxygen is O.5. The method of claim 1 , wherein the source of the adsorbed oxygen is O.6. The method of claim 1 , wherein Ris C1-C8 straight chain alkyl.7. The method of claim 6 , wherein Ris methyl.8. The method of claim 1 , wherein Ris C1-C8 straight chain alkyl.9. The method of claim 8 , wherein Ris methyl.10. The method of claim 1 , wherein X is O claim 1 , and Rand Rare the same.11. The method of claim 1 , wherein X is O claim 1 , and Rand Rare different.12. The method of claim 1 , wherein Ris C1-C8 straight chain alkyl.13. The method of claim 1 , wherein ROH is supplied in the gas phase claim 1 , and the temperature is between 250 K and 300 K. This application claims benefit of U.S. provisional application No. 61/572,416, filed Jul.This invention was made with government support under DE-FG02-84-ER13289 awarded by the U.S. Department of Energy and under CHE-0952790 awarded by the National Science Foundation. The Government has certain rights in the invention.The invention is in the fields of synthetic organic chemistry and catalysis, and relates specifically to a process for preparing carbonates and carbamates. More particularly, the present invention relates to a process for preparing carbonates and carbamates via oxidative carbonylation in the presence of a metallic gold catalyst.Dialkyl carbonates are industrially useful as lubricants, fuel additives, and reactive reagents in a wide variety of processes. In particular, dimethyl carbonate (DMC) has found use as an environmentally-acceptable solvent, high-octane oxygenated fuel additive, and esterifying and methylating agent, and the future demand for DMC is projected to exceed current ...

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Номер записи: 82
09-05-2019 дата публикации

METHOD FOR PRODUCING XYLYLENE DIISOCYANATE (XDI)

Номер: US20190135737A1
Автор: BERNARD Jean-Marie, RATABOUL-LEDUC Anne-Marie, TOURNAYRE Julien
Принадлежит:

Disclosed is to a method for producing xylylene diisocyanate (XDI), in particular meta-xylylene diisocyanate (mXDI), including the following steps: a) phosgenation of xylylene-diamine (XDA), in particular m-xylylene-diamine (mXDA) in the case of mXDI; b) eliminating the hydrochloric acid from the reaction medium obtained in step (a) at a temperature of between 120 and 190° C. and a pressure of between 1 mbar and 20 bar. 116-. (canceled)17. A process for preparing xylylene diisocyanates XDI , in particular meta-xylylene diisocyanate mXDI , comprising the following steps:a. phosgenation of the xylylene diamine XDA, in particular m-xylylene diamine mXDA in the case of mXDI;b. elimination of the hydrochloric acid from the reaction medium obtained in step a) at a temperature of between 120 and 190° C. and a pressure between 1 mbar and 20 bar.18. The process according to claim 17 , wherein step b) is maintained until the assay of the resulting reaction medium indicates allophanoyl chloride content of XDI claim 17 , less than 3% by weight in the reaction medium claim 17 , excluding the amount of solvent claim 17 , phosgene and HCl.19. The process according to claim 17 , wherein at least one solvent is added to the reaction mixture before step b) claim 17 , said solvent being selected from non-reactive solvents with the isocyanate functions claim 17 , alkanes claim 17 , chloroalkanes claim 17 , esters claim 17 , ethers claim 17 , aromatics and halogenated aromatics.20. The process according to claim 19 , wherein the solvent added to the reaction medium is in excess of 30% by weight and advantageously greater than 50% by weight.21. The process according to claim 17 , wherein step b) is carried out in a distillation column.22. The process according to claim 17 , wherein step b) is implemented by making co-current claim 17 , cross-current or counter-current contact between the reaction mixture resulting from the reaction of phosgenation and an inert compound chosen from a ...

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Номер записи: 83
30-04-2020 дата публикации

METHOD FOR PRODUCING ISOCYANATES

Номер: US20200131120A1
Автор: Bruns Rainer, MAUSBACH Artur, Taube Wolfgang
Принадлежит:

The invention relates to a method for preparing an isocyanate by phosgenating the corresponding primary amine in the gas phase, wherein the gaseous reaction product mixture is cooled by being brought into contact with at least one flow stream of a quenching liquid in a quenching zone, wherein the quenching liquid used in total comprises, based on the total mass, organic solvents in a proportion of maximally 50.0% by mass, and the remainder of up to 100% by mass consists of at least the isocyanate to be produced, thereby obtaining a mixture of the reaction product mixture and the quenching liquid. Furthermore, the mixture obtained in this manner of the reaction product mixture and the quenching liquid is separated into a liquid and a gaseous phase in a collection zone, and a liquid solvent intermediate flow comprising more than 50.0% by mass of organic solvents, based on the total mass of the liquid solvent intermediate flow, is conducted into the collecting zone and/or into a collecting tank arranged fluidically downstream of the collection zone for the liquid phase obtained in the collection zone. 1. A process for preparing an isocyanate by phosgenating the corresponding primary amine in the gas phase , comprising:(i) providing a gaseous stream of a primary amine;(ii) providing a gaseous phosgene stream;(iii) mixing the gaseous stream of the primary amine from step (i) and the gaseous phosgene stream from step (ii) to give a gaseous reaction mixture while maintaining a stoichiometric excess of phosgene relative to primary amino groups in a mixing zone and conducting the gaseous reaction mixture thus obtained through a reaction zone for reaction of the primary amine with phosgene to obtain a gaseous reaction product mixture;(iv) cooling the gaseous reaction product mixture obtained after passage through the reaction zone from step (iii) by contacting the gaseous reaction mixture with at least one stream of a quench liquid in a quench zone, where the total quench ...

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Номер записи: 84
26-05-2016 дата публикации

Method for producing meta-xylylenediisocyanates

Номер: US20160145201A1
Автор: Chitoshi Shimakawa, Hidetaka Tsukada, Kouya Kojima, Mamoru Takashina, Naoyuki Kakinuma
Принадлежит: Mitsui Chemicals Inc

A method for producing meta-xylylenediisocyanates includes a reaction step in which monohalogenated benzenes, formaldehydes, and an amide compound represented by general formula (1) below are allowed to react in the presence of an acidic liquid to produce a bisamide compound; a dehalogenation step in which in the bisamide compound, the halogen atom derived from the monohalogenated benzenes is replaced with a hydrogen atom; and a thermal decomposition step in which the bisamide compound from which the halogen atom is eliminated is subjected to thermal decomposition. In the reaction step, the acidic liquid contains inorganic acid, the equivalent ratio of the hydrogen atom of the inorganic acid relative to the monohalogenated benzenes is more than 14, the acidic liquid has an inorganic acid concentration of more than 90 mass %, and the reaction temperature is more than 10° C. General formula (1): wherein R 1 represents an alkoxy group or an amino group.

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Номер записи: 85
26-05-2016 дата публикации

HYDROLYSIS-RESISTANT POLYURETHANE MOULDING

Номер: US20160145372A1
Автор: DOROODIAN Amir, He Yan
Принадлежит:

The present invention relates to a process for producing polyurethane moldings, wherein (a) organic polyisocyanates are mixed with (b) compounds having at least two hydrogen atoms which are reactive toward isocyanate and comprising polyesterol (b1) and at least one compound (b2) obtainable by alkoxylation of an aromatic starter molecule, (c) blowing agent, (d) catalyst, and (e) optionally other auxiliaries and/or additives to form a reaction mixture and the reaction mixture is introduced into a mold and allowed to react to give a polyurethane molding. The present invention further relates to polyurethane moldings obtainable by such a process and also the use of these moldings as steering wheel, seat, armrest and in particular as shoe sole. 1. A process for producing polyurethane moldings comprising:combining organic polyisocyanates (a) withcompounds (b) having at least two hydrogen atoms that are reactive toward isocyanate, the compounds (b) including polyesterol (b1) and at least one compound (b2), which is obtained by alkoxylation of an aromatic starter molecule,a blowing agent,a catalyst, andoptionally other auxiliaries and/or additives to form a reaction mixture; andintroducing the reaction mixture into a mold and allowed to react to give a polyurethane molding having a density of from 150 to 850 g/l.2. The process according to claim 1 , wherein the aromatic starter molecule includes at least two benzene rings.3. The process according to claim 1 , wherein the aromatic starter molecule is a bisphenol or a derivative of a bisphenol.4. The process according to claim 3 , wherein the aromatic starter is bisphenol A or bisphenol S.5. The process according to claim 1 , wherein compound (b2) has a hydroxyl number of from 80 to 400 mg KOH/g.611.-. (canceled)12. The process according to claim 3 , wherein compound (b2) has a hydroxyl number of from 80 to 400 mg KOH/g.13. The process according to claim 1 , wherein the alkoxylation of compound (b2) is obtained with propylene ...

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Номер записи: 86
10-06-2021 дата публикации

METHOD OF PREPARING DIISOCYANATE COMPOSITION AND OPTICAL LENS

Номер: US20210171443A1
Автор: HAN Hyuk Hee, KIM Jeongmoo, MYUNG Jung Hwan, PAI Jaeyoung
Принадлежит:

In the embodiments, an aqueous hydrochloric acid solution instead of hydrogen chloride gas and solid triphosgene instead of phosgene gas may be used in the process of preparing a diisocyanate from a diamine through a diamine hydrochloride. In addition, the embodiments provide processes for preparing a diisocyanate composition and an optical lens of higher quality, in which the reaction temperature of a diamine hydrochloride composition and triphosgene is controlled to a specific range, or a crude diisocyanate composition obtained from the reaction of a diamine hydrochloride composition and triphosgene is distilled at a specific temperature range, or the molar ratio of a diamine hydrochloride and triphosgene is adjusted to a specific range. 1. A process for preparing a diisocyanate composition , which comprises:(1) reacting a diamine with an aqueous hydrochloric acid solution to obtain a diamine hydrochloride composition; and(2) reacting the diamine hydrochloride composition with triphosgene to obtain a diisocyanate composition,wherein the reaction of step (2) is carried out at a temperature of 115° C. to 160° C., or the molar ratio of the diamine hydrochloride composition and triphosgene introduced to the reaction of step (2) is greater than 1:0.70 to less than 0.95.2. The process for preparing a diisocyanate composition of claim 1 , wherein the reaction of the diamine hydrochloride composition and triphosgene of step (2) sequentially comprises:(2-a) mixing the diamine hydrochloride composition with an organic solvent to obtain a first solution;(2-b) mixing triphosgene with an organic solvent to obtain a second solution; and(2-c) introducing the second solution to the first solution and stirring them, wherein the introduction of the second solution and stirring is carried out at a temperature of 115° C. to 160° C.3. The process for preparing a diisocyanate composition of claim 1 , wherein the content of aromatic compounds having a halogen group in the diisocyanate ...

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Номер записи: 87
10-06-2021 дата публикации

METHOD OF PREPARING DIISOCYANATE COMPOSITION AND OPTICAL LENS

Номер: US20210171444A1
Автор: HAN Hyuk Hee, JUNG Jooyoung, KIM Jeongmoo, KYUN Myung-Ok, MYUNG Jung Hwan, PAI Jaeyoung
Принадлежит:

In the embodiments, an aqueous hydrochloric acid solution instead of hydrogen chloride gas and solid triphosgene instead of phosgene gas may be used in the process of preparing a diisocyanate from a diamine through a diamine hydrochloride. In addition, the embodiments provide processes for preparing a diisocyanate composition and an optical lens of higher quality by controlling the water content in the diamine hydrochloride composition for preparing a diisocyanate within a specific range. 1. A process for preparing a diisocyanate composition , which comprises:(1) reacting a diamine composition with an aqueous hydrochloric acid solution to obtain a diamine hydrochloride composition; and(2) reacting the diamine hydrochloride composition with triphosgene to obtain a diisocyanate composition,wherein the diisocyanate composition has a b* value according to the CIE color coordinate of 0.1 to 2.0.2. The process for preparing a diisocyanate composition of claim 1 , wherein the content of Fe ions in the aqueous hydrochloric acid solution is 0.5 ppm or less.3. The process for preparing a diisocyanate composition of claim 1 , wherein the diamine hydrochloride composition has a b* value according to the CIE color coordinate of 1.5 or less when dissolved in water at a concentration of 8% by weight.4. The process for preparing a diisocyanate composition of claim 3 , wherein the b* value according to the CIE color coordinate of the diamine hydrochloride composition is adjusted by washing it with a solvent having a polarity of 5.7 or less.5. The process for preparing a diisocyanate composition of claim 1 , which further comprises measuring the b* value according to the CIE color coordinate of the diamine hydrochloride composition.6. The process for preparing a diisocyanate composition of claim 1 , wherein the diisocyanate composition is obtained by distillation after the reaction of the diamine hydrochloride composition and triphosgene claim 1 , and the distillation comprises ...

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Номер записи: 88
10-06-2021 дата публикации

METHOD OF PREPARING DIISOCYANATE COMPOSITION AND OPTICAL LENS

Номер: US20210171445A1
Автор: HAN Hyuk Hee, JUNG Jooyoung, KIM Jeongmoo, KYUN Myung-Ok, MYUNG Jung Hwan, PAI Jaeyoung
Принадлежит:

In the embodiments, an aqueous hydrochloric acid solution and an organic solvent instead of hydrogen chloride gas and solid triphosgene instead of phosgene gas may be used in the process of preparing a diisocyanate from a diamine through a diamine hydrochloride. In addition, the embodiments provide processes for preparing a diisocyanate composition and an optical lens, which are excellent in yield and quality with mitigated environmental problems by controlling the total content of metals, cations, or anions in a diamine hydrochloride composition. 1. A process for preparing a diisocyanate composition , which comprises:obtaining a diisocyanate composition using a diamine hydrochloride composition,wherein the total content of metals in the diamine hydrochloride composition is 100 ppm or less.2. The process for preparing a diisocyanate composition of claim 1 , wherein the diamine hydrochloride composition is obtained by a process comprising:reacting a diamine with an aqueous hydrochloric acid solution; andadding a first organic solvent to the reaction resultant of the diamine and the aqueous hydrochloric acid solution,wherein the first organic solvent is introduced to the reaction in an amount of 1.3 to 1.5 times the weight of the aqueous hydrochloric acid solution, andthe diamine and the aqueous hydrochloric acid solution are introduced to the reaction at an equivalent ratio of 1:2 to 5.3. The process for preparing a diisocyanate composition of claim 2 , wherein the first organic solvent may comprise an amphiphilic organic solvent claim 2 , andthe first organic solvent is at least one selected from the group consisting of diethyl ether, diisopropyl ether, dioxane, tetrahydrofuran, methanol, ethanol, dimethyl sulfoxide, dimethylformamide, acetonitrile, acetone, trichloroethylene, tetrachloroethane, trichloroethanol, n-butanol, isobutanol, methyl ethyl ketone, methyl butyl ketone, isopropanol, hexane, chloroform, and methyl acetate.4. The process for preparing a ...

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Номер записи: 89
10-06-2021 дата публикации

METHOD OF PREPARING DIISOCYANATE COMPOSITION

Номер: US20210171446A1
Автор: HAN Hyuk Hee, KIM Jeongmoo, MYUNG Jung Hwan, PAI Jaeyoung
Принадлежит:

The embodiments provide processes for preparing a diisocyanate composition and an optical lens, which are excellent in yield and quality with mitigated environmental problems by using a solid triphosgene composition instead of phosgene gas in the process of preparing a diisocyanate from a diamine through a hydrochloride thereof and by controlling the content of a decomposition product in a triphosgene composition, the b* value according to CIE color coordinate of the triphosgene composition in an organic solvent, or the content of water in the triphosgene. 1. A process for preparing a diisocyanate composition , which comprises:reacting a diamine hydrochloride composition with a triphosgene composition to obtain a diisocyanate composition,wherein the content of a decomposition product of triphosgene in the triphosgene composition is less than 1% by weight.2. The process for preparing a diisocyanate composition of claim 1 , wherein the decomposition product of triphosgene comprises carbon tetrachloride claim 1 , and the content of the decomposition product of triphosgene in the triphosgene composition is adjusted by washing the triphosgene composition with diethyl ether at 5σC or lower.3. The process for preparing a diisocyanate composition of claim 1 , wherein the diamine hydrochloride composition and the triphosgene composition are introduced to the reaction at an equivalent ratio of 1:1 to 5 claim 1 , and the reaction of the diamine hydrochloride composition and the triphosgene composition is carried out at a temperature of 110° C. to 160° C.4. The process for preparing a diisocyanate composition of claim 1 , wherein the diisocyanate composition is obtained by subjecting the reaction resultant obtained by reacting the diamine hydrochloride composition and the triphosgene composition to first distillation at 40° C. to 60° C. for 2 to 8 hours and second distillation at 80° C. to 160° C. for 2 to 10 hours.5. The process for preparing a diisocyanate composition of ...

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Номер записи: 90
10-06-2021 дата публикации

DIAMINE COMPOSITION, AND METHOD OF PREPARING DIISOCYANATE COMPOSITION

Номер: US20210171447A1
Автор: HAN Hyuk Hee, JUNG Jooyoung, KIM Jeongmoo, KYUN Myung-Ok, MYUNG Jung Hwan, PAI Jaeyoung
Принадлежит:

The diamine composition according to an embodiment of the present invention comprises a benzylmonoamine having a methyl group in an amount of 10 ppm to 2,000 ppm in the composition. When it is used for the preparation of a diisocyanate composition and an optical material, it is possible to improve the optical characteristics by preventing the occurrence of yellowing, striae, and cloudiness in the optical material and enhancing the mechanical properties such as impact resistance at the same time. In addition, in the process for preparing a diisocyanate composition according to another embodiment, the b* value according to the CIE color coordinate of a diamine composition is adjusted to a specific range, whereby it is possible to enhance not only the yield and purity of the diisocyanate composition but also the optical characteristics of the final optical lens. Thus, the process for preparing a diisocyanate composition can be applied to the preparation of a plastic optical lens of high quality. 1. A diamine composition , which comprises a diamine; and a benzylmonoamine having a methyl group in an amount of 10 ppm to 2 ,000 ppm.3. The diamine composition of claim 1 , which comprises 99% by weight to less than 100% by weight of a diamine based on the total weight of the composition claim 1 , and the diamine comprises at least one selected from the group consisting of orthoxylylenediamine (o-XDA) claim 1 , metaxylylenediamine (m-XDA) claim 1 , and paraxylylenediamine (p-XDA).4. The diamine composition of claim 3 , which comprises metaxylylenediamine (m-XDA) in an amount of 99.5% by weight to less than 100% by weight based on the total weight of the composition.5. A process for preparing a diamine composition claim 3 , which comprises:reacting a diamine composition with an aqueous hydrochloric acid solution to obtain a diamine hydrochloride composition; andobtaining a diisocyanate composition using the diamine hydrochloride composition and triphosgene,wherein the diamine ...

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Номер записи: 91
10-06-2021 дата публикации

DIISOCYANATE COMPOSITION, PREPARATION METHOD THEREOF AND OPTICAL MATERIAL USING SAME

Номер: US20210171448A1
Автор: HAN Hyuk Hee, JUNG Jooyoung, KIM Jeongmoo, KYUN Myung-Ok, MYUNG Jung Hwan, PAI Jaeyoung
Принадлежит:

In the embodiments, an aqueous hydrochloric acid solution instead of hydrogen chloride gas and solid triphosgene instead of phosgene gas may be used in the process of preparing a diisocyanate from a diamine through a diamine hydrochloride. In addition, the embodiments provide processes for preparing a diisocyanate composition and an optical lens of high quality in which the content of water, the content of cations, or the content of an aromatic compound containing 3 or more of chlorine (Cl) in the organic solvent used in the reaction of a diamine hydrochloride composition and triphosgene is adjusted to a specific range. 1. A process for preparing a diisocyanate composition , which comprises:(1) reacting a diamine with an aqueous hydrochloric acid solution to obtain a diamine hydrochloride composition; and(2) reacting the diamine hydrochloride composition with triphosgene in an organic solvent to obtain a diisocyanate composition,wherein the content of water, the content of cations, or the content of an aromatic compound containing 3 or more of chlorine (Cl) in the organic solvent is adjusted.2. The process for preparing a diisocyanate composition of claim 1 , wherein the content of water in the organic solvent is 200 ppm or less.3. The process for preparing a diisocyanate composition of claim 1 , wherein the organic solvent comprises 1 claim 1 ,2-dichlorobenzene (ODCB) claim 1 , and the organic solvent comprises an aromatic compound containing 3 or more of chlorine (Cl) in an amount of 5 claim 1 ,000 ppm or less.4. The process for preparing a diisocyanate composition of claim 1 , wherein the organic solvent comprises 1 claim 1 ,2-dichlorobenzene (ODCB) claim 1 , and wherein the total content of cations in the organic solvent is adjusted to 1 ppm to 5 ppm.5. The process for preparing a diisocyanate composition of claim 1 , wherein the content of water in the organic solvent is adjusted by dehydration under a reduced pressure claim 1 ,the dehydration is performed for ...

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Номер записи: 92
10-06-2021 дата публикации

METHOD OF PREPARING DIISOCYANATE COMPOSITION

Номер: US20210171449A1
Автор: HAN Hyuk Hee, KIM Jeongmoo, MYUNG Jung Hwan, PAI Jaeyoung
Принадлежит:

In the embodiments, an aqueous hydrochloric acid solution instead of hydrogen chloride gas and solid triphosgene instead of phosgene gas may be used in the process of preparing a diisocyanate from a diamine through a diamine hydrochloride. In addition, the embodiments provide processes for preparing a diisocyanate composition and an optical lens, which are excellent in yield and quality with mitigated environmental problems by controlling the size of the diamine hydrochloride composition, the b* value according to the CIE color coordinate of the diamine hydrochloride composition, or the content of water in the diamine hydrochloride composition within a specific range. 1. A process for preparing a diisocyanate composition , which comprises:reacting a diamine with an aqueous hydrochloric acid solution to obtain a diamine hydrochloride composition; andobtaining a diisocyanate composition using the diamine hydrochloride composition,wherein the average particle diameter of the diamine hydrochloride composition is 10 μm to 1,000 μm.2. The process for preparing a diisocyanate composition of claim 1 , wherein in the reaction of the diamine and the aqueous hydrochloric acid solution claim 1 , the diamine is introduced to the reaction in an amount of 15% to 60% based on the weight of the aqueous hydrochloric acid solution per hour.3. The process for preparing a diisocyanate composition of claim 2 , wherein the reaction of the diamine and the aqueous hydrochloric acid solution sequentially comprises:(1a) introducing the aqueous hydrochloric acid solution to a first reactor;(1b) introducing the diamine to the first reactor and stirring them; and(1c) introducing the first organic solution to the first reactor and stirring them, wherein the introduction of the diamine is performed while the temperature of the first reactor is maintained at 20° C. to 60° C.4. The process for preparing a diisocyanate composition of claim 3 , wherein the reaction of the diamine and the aqueous ...

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Номер записи: 93
10-06-2021 дата публикации

PROCESS FOR SEPARATING AN ORGANIC ISOCYANATE

Номер: US20210171450A1
Автор: Duerig Dominik, Kobylka Manfred, Merkel Michael, Seidel Bernhard
Принадлежит:

Provided is a process for separating an organic isocyanate prepared by reacting an organic amine with a stoichiometric excess of phosgene in the gas phase from the gaseous crude product obtained in the reaction, the process comprising the steps of (i) at least partially condensing the crude product stream containing at least the isocyanate, hydrogen chloride and unconverted phosgene by contacting with at least one liquid stream containing at least one quench liquid in a first separation apparatus to obtain a liquid stream containing at least some of the quench liquid and some of the isocyanate and a gas stream containing at least hydrogen chloride, evaporated quench liquid and phosgene, (ii) discharging the liquid stream obtained in step (i) via a first liquid outlet and of the gas stream obtained in (i) via a first gas conduit and (iii) at least partially condensing and/or absorbing the gas stream discharged in step (ii) through the first gas conduit, wherein that the at least partial condensation and/or absorption is effected in step (iii) by direct introduction of at least one cooling fluid, wherein the cooling fluid is introduced directly into the first gas conduit via at least one addition unit assigned to the first gas conduit. 18-. (canceled)10. The process as claimed in claim 9 , wherein the weight ratio of the cooling fluid introduced to the gas stream conducted through the first gas conduit is 1:100 to 10:1.11. The process as claimed in claim 9 , wherein the cooling fluid is selected to correspond to the solvent used as quench liquid in step (i).12. The process as claimed claim 9 , further including the steps of(iv) separating the gas stream from the first gas conduit in a second separation unit into a liquid stream and a gas stream and(v) recycling the liquid stream obtained in step (iv) as quench liquid via a second liquid conduit into the first separation unit.13. The process as claimed in claim 9 , wherein the cooling fluid is selected from the group ...

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Номер записи: 94
10-06-2021 дата публикации

DIISOCYANATE COMPOSITION, PREPARATION METHOD THEREOF AND OPTICAL MATERIAL USING SAME

Номер: US20210171451A1
Автор: HAN Hyuk Hee, JUNG Jooyoung, KIM Jeongmoo, KYUN Myung-Ok, MYUNG Jung Hwan, PAI Jaeyoung
Принадлежит:

The diisocyanate composition according to an embodiment of the present invention comprises, in the composition, a benzyl isocyanate having a methyl group in an amount of 5 ppm to 200 ppm, an aromatic compound having a halogen group in an amount of 5 ppm to 1,000 ppm, a benzyl isocyanate having an ethyl group in an amount of 1 ppm to 1,000 ppm, or a combination thereof. It is possible to improve the optical characteristics by preventing the occurrence of yellowing, striae, and cloudiness and to enhance the mechanical properties such as impact resistance at the same time. Thus, it can be advantageously used to prepare an optical material of high quality. 1. A diisocyanate composition , which comprises:a diisocyanate; anda benzyl isocyanate having a methyl group in an amount of 5 ppm to 200 ppm, an aromatic compound having a halogen group in an amount of 5 ppm to 1,000 ppm, a benzyl isocyanate having an ethyl group in an amount of 1 ppm to 1,000 ppm, or a combination thereof.2. The diisocyanate composition of claim 1 , wherein the benzyl isocyanate having a methyl group comprises at least one selected from the group consisting of 2-methylbenzyl isocyanate claim 1 , 3-methylbenzyl isocyanate claim 1 , and 4-methylbenzyl isocyanate claim 1 ,the aromatic compound contains two or more chlorine, andthe benzyl isocyanate having an ethyl group comprises at least one selected from the group consisting of 1-ethyl-2-(isocyanatomethyl)benzene, 1-ethyl-3-(isocyanatomethyl)benzene, and 1-ethyl-4-(isocyanatomethyl)benzene.4. The diisocyanate composition of claim 1 , wherein the diisocyanate comprises m-xylylene diisocyanate claim 1 , p-xylylene diisocyanate claim 1 , or a mixture thereof claim 1 ,the composition comprises the m-xylylene diisocyanate in an amount of 99.5% by weight to less than 100% by weight based on the total weight of the composition, andthe composition comprises the p-xylylene diisocyanate in an amount of greater than 0% by weight to 0.5% by weight based on the ...

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Номер записи: 95
10-06-2021 дата публикации

DIISOCYANATE COMPOSITION FOR OPTICAL LENS AND PREPARATION METHOD THEREOF

Номер: US20210171452A1
Автор: HAN Hyuk Hee, KIM Jeongmoo, MYUNG Jung Hwan, PAI Jaeyoung
Принадлежит:

According to an embodiment, the pH of a diisocyanate composition and a diamine hydrochloride composition used in the preparation of an optical lens is adjusted to a specific range, whereby it is possible to enhance not only the yield and purity of the diisocyanate composition but also the optical characteristics of the final optical lens by suppressing the striae and cloudiness. Specifically, according to the process of the embodiment, the amount of an aqueous hydrochloric acid solution introduced to the reaction may be adjusted to control the pH of the diisocyanate composition to a desired range, thereby enhancing the yield and purity. Accordingly, the process for preparing a diisocyanate composition according to the embodiment can be applied to the preparation of a plastic optical lens of high quality. 1. A diisocyanate composition for an optical lens , which has a pH of 5.0 to 5.8.2. The diisocyanate composition for an optical lens of claim 1 , which comprises xylylene diisocyanate claim 1 , wherein the content of the xylylene diisocyanate in the diisocyanate composition is 99.9% by weight or more.3. The diisocyanate composition for an optical lens of claim 1 , wherein the content of chlorine ions in the diisocyanate composition is 100 ppm or less claim 1 , and the pH of the diisocyanate composition is 5.5 to 5.7.4. A process for preparing a diisocyanate composition for an optical lens claim 1 , which comprises:reacting a diamine with an aqueous hydrochloric acid solution to obtain a diamine hydrochloride composition; andobtaining a diisocyanate composition from the diamine hydrochloride composition by a phosgenation reaction,wherein the aqueous hydrochloric acid solution is introduced such that the amount of HCl is 2.02 moles to 4.00 moles per 1 mole of the diamine, andthe diamine hydrochloride composition has a pH of 3.0 to 4.0 when dissolved in water at a concentration of 10% by weight.5. The process for preparing a diisocyanate composition for an optical lens ...

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Номер записи: 96
02-06-2016 дата публикации

Method for producing isocyanates

Номер: US20160152558A1
Автор: Friedhelm Steffens, Jan BUSCH, Markus Hollaus
Принадлежит: Covestro Deutschland AG

The invention relates to a method for producing an isocyanate by reacting the corresponding primary amine with phosgene in a reactor ( 100 ) which comprises at least one reaction zone ( 110 ) and a quenching zone ( 120 ) arranged below said reaction zone, having the following steps: (i) introducing a gaseous amine flow ( 1 ) and a gaseous phosgene flow ( 2 ) into the reactor ( 100 ) and reacting the flows in the reaction zone ( 110 ) into a product gas flow ( 3 ) comprising isocyanate and hydrogen chloride and optionally excess phosgene; (ii) introducing the product gas flow ( 3 ) into the quenching zone ( 120 ), in which the product gas flow is cooled by injecting a quenching liquid ( 4 ) via at least one quenching nozzle ( 200 ) such that a liquid flow ( 5 ) comprising the quenching liquid ( 4 ) and isocyanate and a gaseous flow ( 6 ) comprising hydrogen chloride and optionally phosgene are obtained; and (iii) separating the isocyanate from the liquid flow ( 5 ) obtained in step (ii); wherein the temperature T w* , of the wall of the reaction zone ( 110 ) directly above the quenching zone ( 120 ) is kept at a value which lies maximally 4.0%, preferably maximally 2.0%, below the maximum temperature, T w max , of the wall of the reaction zone, said maximum temperature being specified in Kelvin.

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Номер записи: 97
02-06-2016 дата публикации

PROCESS FOR THE PREPARATION OF URETHANES

Номер: US20160152559A1
Автор: Jacob Andreas, Klein Stephan, Mei Fuming, Sundermeyer Jörg, Wershofen Stefan
Принадлежит:

Urethanes are prepared by oxidative carbonylation of at least one amino compound in the presence of carbon monoxide, oxygen and organic, at least one hydroxyl-group-carrying compound. The carbonylation is carried out in the absence of halogen-containing promoters. The carbonylation is also carried out in the presence of a metal complex catalyst which contains neutral bidentate N-chelate ligands of the (N˜N) type, two monoanionic N,O-chelate ligands of the general type (N˜O) or tetradentate dianionic chelate ligands (O˜N˜N˜O). 110-. (canceled)12. The process of claim 11 , wherein the metal complex catalyst is used in a concentration of from 0.1 to 10 mol % claim 11 , based on one mole of amino groups.13. The process of claim 11 , wherein the carbonylation is carried out in methanol claim 11 , ethanol claim 11 , n-butanol claim 11 , or 2 claim 11 ,2 claim 11 ,2-trifluoroethanol.14. The process of claim 11 , wherein ureas groups are formed during the carbonylation claim 11 , wherein these urea groups subsequently react further claim 11 , partially or completely claim 11 , with the organic hydroxyl-group-containing compound by alcoholysis to give the corresponding urethanes.15. The process of claim 11 , in which an aliphatic claim 11 , cycloaliphatic and/or aromatic mono- or di-amino compound is used.16. The process of claim 11 , in which the carbonylation is carried out in the absence of a halogenated solvent.17. A process for the preparation of isocyanates claim 11 , comprising:a) preparing a urethane by carbonylation by the process of 1, andb) thermally cleaving the urethane to obtain the isocyanate.18. The process of claim 17 , wherein the carbonylation and the thermal cleavage take place in one process step. The invention relates to a process for the preparation of urethanes and/or ureas by oxidative carbonylation of amino compounds in the presence of carbon monoxide and oxygen as oxidizing agents and, particularly in the case of the urethanes, in the presence of ...

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Номер записи: 98
07-05-2020 дата публикации

FLOW REACTOR

Номер: US20200139339A1
Автор: Ohishi Takahiro, Ozasa Shiori, Yasukouchi Hiroaki
Принадлежит: KANEKA CORPORATION

The purpose of the present invention is to provide a flow reactor that can ensure safety even if leakage occurs at the connections of the lines. The flow reactor of the present invention is characterized by including one or more line structures, each of the line structures including a raw material feeding line, a reactor unit to react a raw material fed from the raw material feeding line, and a discharge line to discharge a reaction product produced in the reactor unit, wherein the flow reactor includes a vessel in which part or all of the reactor unit and a fluid are accommodated to be capable of being in contact with each other, wherein each of the line structures includes two or more attachable and detachable connections, and wherein at least one of the attachable and detachable connections is accommodated in the vessel. 1. A flow reactor , comprising:at least one line structure each comprising a raw material feeding line, a reactor unit configured to react a raw material fed from the raw material feeding line therein, and a discharge line configured to discharge a reaction product produced in the reactor unit;a vessel accommodating a part or all of the reactor unit and a fluid such that the part or all of the reactor unit and the fluid are capable of contacting with each other,wherein each of the at least one line structure comprises two or more attachable and detachable connections, andwherein at least one of the two or more attachable and detachable connections is accommodated in the vessel.2. The flow reactor according to claim 1 , wherein the at least one line structure comprises a line structure having two or more raw material feeding lines claim 1 , and claim 1 , between the two or more raw material feeding lines and the reactor unit claim 1 , a mixing unit configured to mix raw materials fed from the two or more raw material feeding lines and send a mixture to the reactor unit.3. The flow reactor according to claim 1 , wherein the attachable and ...

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Номер записи: 99
17-06-2021 дата публикации

PLANT AND METHOD FOR PURIFYING AN ISOMERIC MONOMER

Номер: US20210179547A1
Автор: FAESSLER Peter, JANSEN Halbe, Stepanski Manfred
Принадлежит:

A plant for preparing a purified isomeric methylene diphenyl diisocyanate monomer from a mixture of different isomeric monomers is disclosed herein. The plant can comprise a distillation apparatus, which comprises: a) a distillation column including a structured packing, b) a source for a mixture of different isomeric methylene diphenyl diisocyanate monomers, c) an evaporator, d) an overhead vapor condenser, e) optionally, an overhead vacuum system and f) a flow-controlled reflux system. The overhead vapor condenser comprises a shell and tube arrangement and is embodied so as to directly subcool the condensate to less than 47° C. The flow-controlled reflux system comprises a heater, which is embodied so as to reheat a partial stream of the condensate formed in the overhead vapor condenser up to 190° C. 1. A plant for preparing a purified isomeric monomer from a mixture of different isomeric methylene diphenyl diisocyanate monomers , wherein the plant comprises a distillation apparatus , which comprises:a) a distillation column including a structured packing,b) a source for a mixture of different isomeric methylene diphenyl diisocyanate monomers,c) an evaporator,d) an overhead vapor condenser,e) an overhead vacuum system andf) a flow-controlled reflux system,wherein the overhead vapor condenser comprises a shell and tube arrangement configured to directly subcool condensate to less than 47° C., andwherein the flow-controlled reflux system comprises a heater configured to reheat a partial stream of the condensate formed in the overhead vapor condenser up to 190° C.2. The plant in accordance with claim 1 , wherein the plant does not comprise any further distillation column.3. The plant in accordance with claim 1 , wherein the plant further comprises claim 1 , downstream of the distillation apparatus claim 1 , a falling-film crystallization apparatus or a suspension crystallization apparatus.4. The plant in accordance with claim 1 , wherein the source for the mixture of ...

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Номер записи: 100