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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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16-10-2020 дата публикации

Устройство для предъявления электрических импульсов при транслингвальной нейростимуляции

Номер: RU0000200325U1
Автор: Владимир Анатольевич Шаблий
Принадлежит: Акционерное общество "ПК "Альматек"

Полезная модель относится к устройствам для неинвазивной транслигвальной нейростимуляции. Заявленные эффекты достигаются элементом для предъявления электрических импульсов при транслингвальной нейростимуляции, а именно устройством для предъявления электрических импульсов при транслингвальной нейростимуляции, состоящим из по меньшей мере печатной платы со множеством электродов для обеспечения подкожной локальной электрической стимуляции языка, средств для подачи тока на электроды и схемы управления, которая распределяет электрические сигналы на электроды в соответствии с заданным алгоритмом, для управления электрическими сигналами, подаваемыми на электроды, при этом для снижение взаимного влияния элементов схемы на выходные каскады формирователей генерируемых импульсов компоненты указанной схемы управления расположены на печатной плате с двух ее сторон. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 200 325 U1 (51) МПК A61N 1/05 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ (52) СПК A61N 1/05 (2020.05) (21)(22) Заявка: 2020103562, 28.01.2020 (24) Дата начала отсчета срока действия патента: (73) Патентообладатель(и): Акционерное общество "ПК "Альматек" (RU) Дата регистрации: 16.10.2020 Приоритет(ы): (22) Дата подачи заявки: 28.01.2020 (45) Опубликовано: 16.10.2020 Бюл. № 29 2 0 0 3 2 5 R U (54) УСТРОЙСТВО ДЛЯ ПРЕДЪЯВЛЕНИЯ ЭЛЕКТРИЧЕСКИХ ИМПУЛЬСОВ ПРИ ТРАНСЛИНГВАЛЬНОЙ НЕЙРОСТИМУЛЯЦИИ (57) Реферат: Полезная модель относится к устройствам для электроды и схемы управления, которая неинвазивной транслигвальной нейростимуляции. распределяет электрические сигналы на Заявленные эффекты достигаются элементом для электроды в соответствии с заданным предъявления электрических импульсов при алгоритмом, для управления электрическими транслингвальной нейростимуляции, а именно сигналами, подаваемыми на электроды, при этом устройством для предъявления электрических для снижение взаимного влияния элементов схемы импульсов при ...

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Номер записи: 1
19-01-2012 дата публикации

Tunneling tool for implantable leads

Номер: US20120016377A1
Автор: Jesse Geroy
Принадлежит: Greatbatch Ltd

A tunneling tool for creating a pathway for implanting a therapy delivery element in a living body. The tunneling tool includes a malleable elongated shaft having a distal end. A sheath having a lumen is slidably positioned over a portion of the shaft. A primary handle secured to proximal end of the shaft permits a user to advance and manipulate the shaft and the sheath in the living body. A secondary handle with an opening is slidably positioned on the shaft between the primary handle and the sheath. The opening has a diameter less than an outside diameter of a proximal end of the sheath. A locking mechanism releasably engages the secondary handle to the primary handle. The sheath is retained in a desired location within the living body by securing the secondary handle relative to the living body as the primary handle is used to remove the shaft from the sheath.

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Номер записи: 2
19-01-2012 дата публикации

Systems and methods for radial steering of electrode arrays

Номер: US20120016378A1
Автор: Anne Margaret Pianca, Michael Adam Moffitt
Принадлежит: Boston Scientific Neuromodulation Corp

A device for brain stimulation includes a lead having a longitudinal surface, a proximal end and a distal end. A plurality of electrodes are disposed along the longitudinal surface of the lead near the distal end of the lead. At least one marker is disposed on the longitudinal surface of the lead. The at least one marker is configured and arranged to identify a relative position of the plurality of electrodes.

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Номер записи: 3
19-01-2012 дата публикации

Energy efficient high frequency nerve blocking technique

Номер: US20120016448A1
Автор: Dongchul Lee
Принадлежит: Boston Scientific Neuromodulation Corp

A neurostimulation system and method of blocking a neural axon. Time-varying electrical energy is conveyed to a blocking site on the neural axon for an initial phase. The conveyed electrical energy has an amplitude and frequency during the initial phase sufficient to block action potentials from propagating along the neural axon from a location proximal to the blocking site to a location distal to the blocking site. The time-varying electrical energy is conveyed to the blocking site on the neural axon for a subsequent phase contiguous with the initial phase. The conveyed electrical energy has a decreased amplitude and a frequency during the subsequent phase sufficient to maintain blocking of the action potentials along the neural axon from the location proximal to the blocking site to the location distal to the blocking site.

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Номер записи: 4
02-02-2012 дата публикации

Sequential Activation RF Electrode Set for Renal Nerve Ablation

Номер: US20120029500A1
Автор: Mark L. Jenson
Принадлежит: Boston Scientific Scimed Inc

A catheter includes a flexible shaft having a length sufficient to access a patient's renal artery. A treatment element at the distal end of the shaft is dimensioned for deployment within the renal artery. The treatment element comprises a radially expandable structure configured to maintain positioning within the renal artery. A multiplicity of electrodes are spaced apart on the treatment element and configured for switchable activation and deactivation in a predetermined sequence to generate overlapping zones of heating directed at perivascular nerves of the renal artery. The overlapping heating zones comprise a distal zone associated with relatively high current densities at a distance from the treatment element sufficient to ablate the perivascular renal nerves and a proximal zone associated with current densities lower than those of the distal zone and insufficient to cause thermal injury to tissue of the renal artery adjacent the treatment element.

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Номер записи: 5
02-02-2012 дата публикации

Electrode devices with resistive elements

Номер: US20120029582A1
Автор: Ehud Cohen, Shai Ayal
Принадлежит: BioControl Medical BCM Ltd

Apparatus is provided for applying current to a nerve. A cathode is adapted to be placed in a vicinity of a cathodic longitudinal site of the nerve and to apply a cathodic current to the nerve. A primary inhibiting anode is adapted to be placed in a vicinity of a primary anodal longitudinal site of the nerve and to apply a primary anodal current to the nerve. A secondary inhibiting anode is adapted to be placed in a vicinity of a secondary anodal longitudinal site of the nerve and to apply a secondary anodal current to the nerve, the secondary anodal longitudinal site being closer to the primary anodal longitudinal site than to the cathodic longitudinal site.

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Номер записи: 6
16-02-2012 дата публикации

Apparatus, System and Method for Ultrasound Powered Neurotelemetry

Номер: US20120041310A1
Автор: Bruce C. Towe
Принадлежит: Arizona Board of Regents of ASU

The present embodiments provide an apparatus, system, and method for ultrasound powered neurotelemetry. In one embodiment, the apparatus includes a piezoelectric element configured to receive an ultrasonic pulse and convert the electronic pulse into an electric potential. A diode may be coupled to the piezoelectric element, the diode configured to cause an electric current to flow in response to the electric potential. The apparatus may additionally include a reference electrode and a stimulating electrode coupled to the diode. The reference electrode may sense bioelectric activity in a region of body tissue located in proximity to the reference diode. The stimulating electrode may emit a carrier signal, wherein the carrier signal is modulated in response to the bioelectric activity sensed by the reference electrode.

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Номер записи: 7
16-02-2012 дата публикации

Establishing continuity between a shield within an implantable medical lead and a shield within an implantable lead extension

Номер: US20120041529A1
Автор: Bruce R. Mehdizadeh, James M. Olsen, Michael J. Kern
Принадлежит: MEDTRONIC INC

Implantable medical leads and implantable lead extensions include a shield. The implantable medical lead is coupled to the implantable lead extension. Stimulation electrodes of the implantable medical lead contact stimulation connectors within a housing of the implantable extension to establish a conductive pathway for stimulation signals from filars of the implantable extension to filars of the implantable medical lead. Continuity is established between the shield of the implantable medical lead and the implantable extension by providing a radio frequency conductive pathway within the housing. The radio frequency conductive pathway extends from a shield of the implantable extension to a shield connector that contacts a shield electrode of the implantable medical lead. The radio frequency conductive pathway may have various forms such as a jumper wire or an extension of the shield within the implantable extension.

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Номер записи: 8
23-02-2012 дата публикации

Layered electrode for an implantable medical device lead

Номер: US20120046721A1
Автор: Brendan E. Koop
Принадлежит: Cardiac Pacemakers Inc

A medical device lead includes an insulative lead body, a conductor extending through the lead body from a proximal end to a distal end, and an electrode electrically connected to the conductor. The proximal end is adapted to be electrically connected to a pulse generator. The electrode includes a plurality of electrode modules mechanically coupled in a stack of electrode modules. Each electrode module includes a plurality of layers that define substantially similar sized pores such that the stack of electrode modules includes an array of the substantially similar sized pores.

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Номер записи: 9
01-03-2012 дата публикации

Drug eluting coatings for a medical lead and method

Номер: US20120052184A1
Автор: Arienne P. Simon, Daniel J. Cooke, Harshad M. Borgaonkar, Jeannette C. Polkinghorne, Ronald W. Heil, Jr.
Принадлежит: Individual

A medical electrical lead includes a drug eluting coating provided over at least a portion of the lead body. The drug eluting coating can be provided over at least a portion of the lead body and adjacent to at least one electrode located on the lead body. The drug eluting coating can include at least one matrix polymer layer including a polymer admixed with a therapeutic agent. The therapeutic agent, for example, can be an anti-proliferative agent or an anti-inflammatory agent. The matrix polymer can include a medical adhesive. The rate of elution of the drug from the matrix polymer layer is affected by the drug to polymer ratio of the drug in the matrix polymer layer.

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Номер записи: 10
01-03-2012 дата публикации

Electrode catheter, in particular for cardiac therapy

Номер: US20120053668A1
Автор: Carsten Fruendt, Detmar Jadwizak, Jochen Palm, Pierre Weitzig
Принадлежит: Biotronik SE and Co KG

An electrode catheter, in particular for cardiac therapy, includes an elongate, tubular catheter body, an electrode for delivering or measuring an electrical signal, in particular an electrocardiac signal, via its external electrode contact surface, at least one first supply line for the electrical connection of the electrode, at least one second supply line for the electrical connection of a further electrode, a plug terminal connection between the at least one first supply line and the electrode, and an insulated passage of the at least one second supply line through the electrode.

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Номер записи: 11
29-03-2012 дата публикации

Transvenous active fixation lead system

Номер: US20120078266A1
Автор: Archie A. Tyson, Jr.
Принадлежит: MEDTRONIC INC

A medical electrical lead system that includes a catheter extending from a proximal catheter end to a distal catheter end; a lead, insertable within the catheter, including a lead body extending from a proximal lead end to a distal lead end and an active fixation member positioned at the distal lead end; and an advancement tool for advancing the distal lead end outward from the distal catheter end. The advancement tool is adapted to be positioned around the lead body and further adapted to be removably fixedly engaged with the proximal catheter end.

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Номер записи: 12
19-04-2012 дата публикации

Biocompatible electrode

Номер: US20120091011A1
Автор: Anthony H.D. Graham, Chris R. Bowen, John Taylor, Jon Robbins
Принадлежит: University of Bath Research and Innovations Services

A biocompatible electrode formed from an integrated circuit, the electrode comprising: a semiconductor substrate; and an electrode layer at least partially comprising porous valve metal oxide.

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Номер записи: 13
19-04-2012 дата публикации

Sample and Hold Circuitry for Monitoring Voltages in an Implantable Neurostimulator

Номер: US20120092031A1
Автор: Emanuel Feldman, Jess W. Shi, Jordi Parramon
Принадлежит: Boston Scientific Neuromodulation Corp

Sample and hold circuitry for monitoring electrodes and other voltages in an implantable neurostimulator is disclosed. The sample and hold circuitry in one embodiment contains multiplexers to selected appropriate voltages and to pass them to two storage capacitors during two different measurement phases. The capacitors are in a later stage serially connected to add the two voltages stored on the capacitors, and voltages present at the top and bottom of the serial connection are then input to a differential amplifier to compute their difference. The sample and hold circuitry is particularly useful in calculating the resistance between two electrodes, and is further particularly useful when resistance is measured using a biphasic pulse. The sample and hold circuitry is flexible, and can be used to measure other voltages of interest during biphasic or monophasic pulsing.

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Номер записи: 14
26-04-2012 дата публикации

Implantable leads having coiled conductors to reduce rf-induced current

Номер: US20120101558A1
Автор: Greg Kampa, Phong D. Doan
Принадлежит: Pacesetter Inc

An implantable lead assembly includes an outer jacket, first and second coiled conductors, and first and second electrodes. The outer jacket is elongated along a center axis and includes a body that radially extends between opposite interior and exterior surfaces. The interior surface defines an elongated lumen. The coiled conductors are held within the body of the outer jacket between the interior and exterior surfaces of the outer jacket and are wrapped around the lumen and the center axis. The electrodes are coupled with the outer jacket and electrically coupled to the coiled conductors in order to at least one of deliver stimulus pulses or sense electrical activity.

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Номер записи: 15
03-05-2012 дата публикации

Protecting an implantable medical device from effects caused by an interfering radiation field

Номер: US20120109261A1
Автор: Christopher C. Stancer, Michael E. Nowak, Steven D. Goedeke
Принадлежит: MEDTRONIC INC

Techniques are described for protecting an implantable medical device (IMD) from effects caused by interfering radiated fields. An IMD incorporating these techniques may include a telemetry conduction path that includes a first end electrically coupled to a telemetry antenna and a second end electrically coupled to a telemetry circuit disposed within a housing of the IMD. The IMD may further include a stub filter electrically coupled to the telemetry conduction path and configured to attenuate an interfering signal induced in the telemetry conduction path. The stub filter may include a dielectric and a conductor disposed within the dielectric. The conductor may include a first end electrically coupled to the telemetry conduction path and a second end configured in an open circuit configuration. The conductor may have an electrical length approximately equal to one-quarter wavelength of the interfering signal when propagating through the stub filter.

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Номер записи: 16
03-05-2012 дата публикации

Planning System for Neurostimulation Therapy

Номер: US20120109599A1
Автор: Hubert Cécile François MARTENS
Принадлежит: Sapiens Steering Brain Stimulation BV

A system for planning implantation of a neurostimulation probe is provided. The system comprises an input for receiving anatomical data comprising information regarding a position and an orientation of at least one fiber bundle in a target region, an input for receiving therapeutic information comprising information regarding a stimulation preferability of the at least one fiber bundle, an optimization module for based on the position, the orientation and the stimulation preferability of the at least one fiber bundle calculating at least one optimal position and at least one optimal orientation for implantation of the neurostimulation probe at which optimal position and orientation the probe is capable of generating an electric field gradient substantially parallel to at least one fiber bundle with a high stimulation preferability and/or substantially perpendicular to at least one fiber bundle with a low stimulation preferability and an output for providing the optimal position and orientation.

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Номер записи: 17
10-05-2012 дата публикации

Catheter with liquid-cooled control handle

Номер: US20120116393A1
Автор: Ariel Garcia, Arnold Tuason, Assaf Govari, Christopher Beeckler, Dean Ponzi, Eduardo Jimenez, Jeffrey W. Schultz, Mario Solis, Rogelio Plascencia, JR., Yaron Ephrath
Принадлежит: Biosense Webster Inc

An electrophysiologic catheter with an improved control handle is provided. The catheter includes a heat transfer assembly to better dissipate heat in the control handle. The heat transfer assembly includes a pump, a reservoir containing a coolant, a heat transfer member, and a coolant transport network transporting coolant between at least the reservoir and the heat transfer member. In one embodiment, the heat transfer member is located within the control handle as a heat exchanger on the circuit board to receive the coolant for transferring heat from the integrated circuits to the coolant. In another embodiment, the heat transfer member is located on the circuit board directly surrounding the integrated circuits to internally cool the integrated circuit within the control handle. A second heat transfer member is located outside of the control handle as a heat exchanger.

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Номер записи: 18
17-05-2012 дата публикации

Transdermal patch with on-board energy storage device

Номер: US20120123335A1
Автор: Frederick A. Sexton
Принадлежит: Purdue Pharma LP

A transdermal patch can include a drug source, a porator, and an energy storage device on-board the patch. Conductive contact terminals can extend from the energy storage device for connection to an external source of power. The porator operates free of any concurrent connection to any external source of power. A switch can be used to make the selective electrical connection between the porator and the energy storage device. The switch can be arranged to respond to a manual user action after the patch has been adhered to skin, including separation of the porator from a remainder of the patch. Optionally, a series of switches can make electrical connections between the porator and respective individual energy storage devices. In another aspect, a transdermal patch includes a mechanical bias that applies a displacement force to the porator to thereby better ensure good physical contact between the porator and the skin.

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Номер записи: 19
24-05-2012 дата публикации

Peel-away is-4/df-4 lead implant tool with electrical contacts

Номер: US20120130396A1
Автор: Bruce A. Tockman, Peter J. Wolf, Timothy R. Jackson
Принадлежит: Cardiac Pacemakers Inc

A peel-away lead implant tool is described. The peel away lead implant tool is adapted to be disposed over the terminal connector of a lead during an implantation procedure to protect the terminal connector. The peel-away lead implant tool includes a flexible polymer sheath including electrical contacts formed in a contact region of the sheath. The electrical contacts can be either metal foil contacts or conductive polymer contacts and extend from an outer surface to an inner surface of the sheath such that when the testing apparatus is coupled to the lead implant tool, the electrical contacts are pressed into electrical contact with the ring electrodes located on the terminal connector. The lead implant tool also includes various removal means facilitating the easy removal of the implant tool from the terminal connector when the implantation procedure is complete.

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Номер записи: 20
24-05-2012 дата публикации

Insulative structure for mri compatible leads

Номер: US20120130453A1
Автор: Arthur J. Foster, Jeffrey E. Stahmann, Scott R. Stubbs
Принадлежит: Cardiac Pacemakers Inc

A medical device lead includes a proximal connector, an insulative lead body extending distally from the proximal connector. The proximal connector is configured to couple the lead to a pulse generator. A first conductive coil is coupled to the proximal connector and extends through the lead body. The first conductive coil is coupled to a first electrode at a distal end of the first conductive coil. A first magnetically impregnated polymer layer is adjacent the first conductive coil.

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Номер записи: 21
07-06-2012 дата публикации

High Aspect Ratio Microelectrode Arrays Enabled to Have Customizable Lengths and Methods of Making the Same

Номер: US20120138335A1
Автор: Florian Solzbacher, Prashant Tathireddy
Принадлежит: University of Utah Research Foundation UURF

A method of fabricating an array of micro electrodes enabled to have customizable lengths. A substantially criss-cross pattern of channels on a top surface of the work-piece substrate ( 10 ) is formed using electrical discharge machining to form a plurality of shaped columns ( 20 ) having tapered profiles. The shaped columns have a tapering profile which extends at least 50% of the length of the columns. The plurality of shaped columns is etched to sharpen the tapered tips into needle tips forming the array of microelectrodes.

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Номер записи: 22
07-06-2012 дата публикации

Implantable lead including a spark gap to reduce heating in mri environments

Номер: US20120143273A1
Автор: Arthur J. Foster, Scott R. Stubbs
Принадлежит: Cardiac Pacemakers Inc

A medical device lead includes a proximal connector configured to couple the lead to a pulse generator, and an insulative lead body extending distally from the proximal connector. The first lead conductor is coupled to the proximal connector and extends through the lead body. The medical device lead also includes a distal defibrillation electrode. A first spark gap is connected between the first lead conductor and the distal defibrillation electrode and has a breakdown voltage that prevents transmission of magnetic resonance imaging (MRI) induced signals from the first lead conductor to the distal defibrillation electrode in an MRI environment and allows transmission of therapy signals to the distal defibrillation electrode.

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Номер записи: 23
07-06-2012 дата публикации

Systems, devices, and methods for monitoring and analyzing research animal behavior before, during and after brain electrical stimulation

Номер: US20120143280A1
Автор: Nicholas Robert Hasulak
Принадлежит: NeuroPace Inc

Described are systems, devices and methods for facilitating the delivery of stimulation to, and the monitoring and recording of physiological signals (e.g., electroencephalographic signals) from a research subject. Devices include a headmount that includes a cranial frame and a headstage, and a connection between the headmount and external equipment used for stimulation, monitoring, and/or recording that is robust physically and electrically to optimize stimulation, monitoring and recording even while the subject remains ambulatory. In some embodiments, a hinged headmount allows the configuration to be easily manipulated during attachment and any subsequent adjustment or reattachment procedures and permits easy access to any wires or other components implanted in the subject. In some embodiments, a flexible cable extends out from the headmount at an acute angle relative to a horizontal plane of the headmount, to optimize strain relief as the subject moves about while attached to any stimulation, monitoring and/or recording equipment.

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Номер записи: 24
07-06-2012 дата публикации

Lead fixation device for securing a medical lead in a human patient

Номер: US20120143297A1
Автор: David Greene
Принадлежит: NeuroPace Inc

A lead fixation device for securing a medical lead in a human patient includes: a single-piece structure comprising: a top surface; a bottom surface; an outer perimeter; and an inner perimeter, the inner perimeter comprising: a diameter approximately equal to or smaller than a diameter of a burr hole into which the lead fixation device is designed to be deployed; a central bore extending longitudinally from the top surface through to the bottom surface, a portion of the central bore being located in approximately a center of the lead fixation device and comprising a central bore diameter; and at least one retention tract formed in the top surface of a cap of the lead fixation device, the retention tract configured for retaining, with an interference fit, a portion of a body of the medical lead in the lead fixation device.

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Номер записи: 25
14-06-2012 дата публикации

Connector assemblies and contacts for implantable medical electrical systems

Номер: US20120149254A1
Автор: Andrew J. Ries, Charles E. Peters, James A. Alexander, John E. Kast, Michael J. Baade
Принадлежит: MEDTRONIC INC

A connector assembly of a medical electrical device includes a plurality of electrical contacts and an insulative base that supports the plurality of electrical contacts and extends between the plurality of electrical contacts and a housing of the device, and, wherein at least one contact of the plurality includes an elongate electrical coupling receptacle in which a first part of a feedthrough member extends, being fixedly coupled thereto. The feedthrough member further includes a second part and a bend, which is located between the first and second parts. The second part of the feedthrough member extends away from the contact and through a port formed in the insulative base adjacent to the contact.

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Номер записи: 26
14-06-2012 дата публикации

Seizure prediction and neurological disorder treatment

Номер: US20120150257A1
Автор: Dorian Aur, Izumi Toyoda, Mark R. BOWER, Paul Buckmaster
Принадлежит: Leland Stanford Junior University

A prediction and stimulation system or method is provided for neurological disorders characterized by a local dysfunction in neuronal activity regulation. An array of electrodes detects neuronal electrical activity of selected brain region. A detection module detects in each electrode changes in electric field and neuronal activity. A prediction module predicts for each electrode abnormal regimes determined by neurological disorder. A neuromodulation module interfaced with the electrodes selects one or more electrodes in the array where a predefined threshold has been exceeded and stimulates the brain region through each of these selected electrodes using an intermittent therapeutic stimulation pattern with a frequency between 150 and 200 Hz. The provided therapy allows for seizure prediction and detection with high accuracy, potential low risk and increased battery life. The flexibility of the method and system allows it to be used in different neurological disorders by tuning the parameters using a calibration procedure.

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Номер записи: 27
21-06-2012 дата публикации

Cochlear Implant with Cochleostomy Ground

Номер: US20120158095A1
Автор: Claude Jolly
Принадлежит: MED EL Elektromedizinische Geraete GmbH

A cochlear implant electrode arrangement is described. An electrode lead is connected to an implantable stimulator and contains electrode wires for carrying stimulation signals from the implantable stimulator. An electrode array penetrates through a cochleostomy opening into a patient cochlea for immersion in cochlear fluid within the cochlea. The electrode array has electrode contacts for delivering the stimulation signals to adjacent neural tissue. A cochleostomy ground contact at the cochleostomy opening separates the electrode lead and the electrode array and provides a return current path for the stimulation signals. There may also be a stimulator ground contact on an outer surface of the implantable stimulator that provides a second return current path for the stimulation signals.

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Номер записи: 28
21-06-2012 дата публикации

Direct memory access (dma) controlled stimulation

Номер: US20120158096A1
Автор: Neil S. Sherman
Принадлежит: Spinal Modulation LLC

An implantable stimulation system (e.g., an implantable neurostimulation system (INS)) comprises memory including a first table and a second table. The first table stores blocks of stimulation event data corresponding to stimulation events that are to be performed during a period of time (e.g., a 0.5 sec. or 1 sec. period of time). The second table stores blocks of next stimulation event time data corresponding to the period of time. The implantable stimulation system also includes a direct memory access (DMA) controller including a first DMA channel and a second DMA channel. The first DMA channel selectively transfers one of the blocks stimulation event data from the first table to one or more registers that are used to control stimulation events. The second DMA channel selectively transfers one of the blocks of next stimulation event time data from the second table to a timer that is used to control timing associated with the stimulation events. In this manner, the DMA controller is able to control stimulation.

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Номер записи: 29
21-06-2012 дата публикации

Lead having a conductive polymer conductor

Номер: US20120158107A1
Автор: Jared Rud, Peter J. Wolf, Shrojalkumar Desai
Принадлежит: Cardiac Pacemakers Inc

A medical electrical lead includes a conductive polymer conductor fabricated from a conductor-filled polyisobutylene urethane, urea or urethane/urea copolymer.

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Номер записи: 30
28-06-2012 дата публикации

Medical electrical lead having biological surface and methods of making and using same

Номер: US20120165913A1
Автор: Zhongping C. Yang
Принадлежит: MEDTRONIC INC

An implantable electrical lead suitable for left sided cardiac placement, the implantable medical electrical lead having an external blood contacting surface having an external coating including a monolayer of at least one biological agent that promotes endothelialization covalently attached to a polymeric lead surface.

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Номер записи: 31
05-07-2012 дата публикации

Extended pain relief via high frequency spinal cord modulation, and associated systems and methods

Номер: US20120172946A1
Автор: Andre B. Walker, Konstantinos Alataris
Принадлежит: Individual

Extended pain relief via high frequency spinal cord modulation, and associated systems and methods. A method for treating a patient in accordance with a particular embodiment includes selecting a neural modulation site to include at least one of a dorsal root entry zone and dorsal horn of the patient's spinal cord, and selecting parameters of a neural modulation signal to reduce patient pain for a period of time after ceasing delivery of the signals, the period of time being at least one tenth of one second.

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Номер записи: 32
19-07-2012 дата публикации

Percutaneous leads with laterally displaceable portions, and associated systems and methods

Номер: US20120185026A1
Автор: C. Lance Boling
Принадлежит: Nevro Corp

Percutaneous leads with laterally displaceable sections, and associated systems and methods are disclosed. A device in accordance with a particular embodiment includes a lead body that in turn includes first, second and third percutaneous portions. The first portion can carry an electrical contact, the second portion can be spaced apart from the first portion, and the third portion can be positioned between the first and second portions along a deployment axis. The third portion can have a stiffness in a direction transverse to the deployment axis that is less than a stiffness of both the first and second portions transverse to the deployment axis, and a diameter that is less than corresponding diameters of the first and second portions.

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Номер записи: 33
26-07-2012 дата публикации

Hearing Aid Microactuator

Номер: US20120190914A1
Автор: Armand P. Neukermans, S. George Lesinski
Принадлежит: OTOKINETICS Inc

A fenestration piercing the otic capsule bone of the cochlea receives a therapeutic appliance, such as a microactuator, plug, micropump for drug or therapeutic agent delivery, electrode, and the like. Several different ways of achieving a ‘water tight’ seal between the otic capsule bone and the therapeutic appliance are provided. The therapeutic appliance may be implanted with or without a sheath or sleeve lining the wall of the fenestration formed using specialized surgical burrs. The burrs permit safely fenestrating the otic capsule bone adjacent to the scala tympani of the cochlea without damaging the basilar membrane or organ of corti. This approach may also be adopted for safely fenestrating other areas of the inner ear such as the scala vestibuli, bony labyrinth of semicircular canals, or walls of the vestibule, or the oval or round windows thereof.

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Номер записи: 34
26-07-2012 дата публикации

Apparatus and Methods for Determining a Subject's Response to Catheter-Based Ablation Therapy Based on Spectral Mapping During Sinus Rhythm

Номер: US20120191087A1
Автор: Enrique Indalecio Pachón Mateos, José Carlos Pachón Mateos
Принадлежит: St Jude Medical Atrial Fibrillation Division Inc

Apparatus for curative ablation are provided to achieve the inactivation or destruction of fibrillar myocardium of the so-called AF nests. In addition, fibrillar myocardium may be identified and mapped by spectral analysis and phase study of the tissue during sinus rhythm. The procedure may be performed by transseptal puncture using only one catheter for ablation and mapping. The methods may be used to localize the application targets even during an arrhythmia.

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Номер записи: 35
02-08-2012 дата публикации

Peripheral nerve blockade device

Номер: US20120197214A1
Автор: Brian Newell Vaughan, Douglas Paul Stewart, Mark David Manley
Принадлежит: Individual

A continuous nerve block apparatus comprising: (a) a hollow needle including a conduit extending between a proximal end and a distal end, the distal end being beveled between ten and fifty degrees; and, (b) a connector operatively coupled to the hollow needle, the connector including at least a first through passage in fluid communication with the conduit of the hollow needle, the connector including a first orifice allowing fluid communication from an exterior of the connector to the first through passage, the connector also including at least one valve.

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Номер записи: 36
02-08-2012 дата публикации

Leads with spiral of helical segmented electrode arrays and methods of making and using the leads

Номер: US20120197375A1
Автор: Anne Margaret Pianca, Matthew Lee Mcdonald
Принадлежит: Boston Scientific Neuromodulation Corp

A stimulation lead includes a lead body having a longitudinal surface, a distal end, a proximal end, and a shaft extending along at least a portion of the distal end of the lead body. The stimulation lead also includes multiple segmented electrode members disposed on the shaft along the longitudinal surface of the lead body near the distal end of the lead body. Each segmented electrode member includes a ring structure which forms at least a partial ring and is disposed on the shaft, and a segmented electrode coupled to the ring and having an exposed surface configured and arranged for stimulating tissue when the stimulation lead is implanted.

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Номер записи: 37
09-08-2012 дата публикации

Nerve stimulator

Номер: US20120203245A1
Автор: Hinako Kaji, Hiroyuki Imabayashi, Kazuo Shimizu, Masamichi Noguchi
Принадлежит: Olympus Corp

A nerve stimulation electrode implantation system includes: an introduction portion that has a cylindrical main body which has an internal cavity, and an incision component which has a blunt dissection portion that bluntly dissects biological tissue, and which is formed so as to be transparent, and which is attached to a distal end portion of the main body; an observation portion that is inserted into the introduction portion such that it is able to observe the periphery of the incision component through the incision component; and a peeling portion that is positioned such that it is able to rotate around its own axis and is able to move relatively in this axial direction relative to the introduction portion, and that removes peripheral tissue from the periphery of the nerve tissue.

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Номер записи: 38
09-08-2012 дата публикации

Implantable electrode array assembly with extraction sleeve/tether

Номер: US20120203246A1
Автор: Douglas A. Staunton, John J. JANIK, Richard F. Huyser
Принадлежит: Individual

An implantable electrode array including a carrier on which plural electrodes are disposed. Also disposed on the carrier is an array antenna over which signals are wirelessly received. A tether is connected to the carrier. A tether antenna is attached to the tether. After the electrode array is implanted, during a trial period instructions and power are transmitted to the array antenna over the tether antenna. If the trial is successful, the tether is disconnected from the electrode array. If the trial is not successful and extraction of the array is necessary, extraction is accomplished by pulling on the tether. Electrode array removal may be facilitated by the pulling of the array into an extraction tube disposed over the tether.

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Номер записи: 39
09-08-2012 дата публикации

Leads with segmented electrodes for electrical stimulation of planar regions and methods of making and using

Номер: US20120203316A1
Автор: Anne Margaret Pianca, Michael Adam Moffitt
Принадлежит: Boston Scientific Neuromodulation Corp

One embodiment is a stimulation lead that includes a lead body having a longitudinal surface, a distal end, and a proximal end; and multiple electrodes disposed along the longitudinal surface of the lead body near the distal end of the lead body. The electrodes include multiple groups of segmented electrodes with each group of segmented electrodes having multiple segmented electrodes disposed at a same longitudinal position along the lead. For at least one first group of segmented electrodes, a first pair of the segmented electrodes in the first group are disposed on opposite sides of the lead body and are electrically ganged together by a conductor therebetween.

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Номер записи: 40
16-08-2012 дата публикации

Apparatus And Method For Modulating Neurochemical Levels In the Brain

Номер: US20120209347A1
Автор: David W. Roberts, James C. Leiter, Mykyta M. Chemov
Принадлежит: Dartmouth College

A treatment for Parkinson's Disease uses a stimulus electrode implanted in a subthalamic nucleus with a chemosensor implanted in a globus pallidus pars interna (GPi) of the subject. A level of a neurochemical is sensed with the chemosensor, and compared to a desired level. When the level of the neurochemical is less than desired, an electrical stimulation is provided to the stimulus electrode. In alternative embodiments, the neurochemical sensed is glutamate or dopamine. An alternative system uses a chemosensor implanted in the striatum instead of the GPi. An alternative system for treating benign essential tremor uses a stimulus electrode implanted in the thalamus with feedback taken from a chemosensor in the striatum.

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Номер записи: 41
23-08-2012 дата публикации

Method and Device for Treating Cardiac Arrhythmias

Номер: US20120215269A1
Автор: Harikrishna Tandri, Leslie Tung, Natalia Trayanova, Ronald David Berger, Seth Weinberg
Принадлежит: JOHNS HOPKINS UNIVERSITY

The present invention provides both methods and devices for termination of arrhythmias, such as ventricular or atrial tachyarrhythmias. The device and method involves application of alternating current (AC) for clinically significant durations at selected therapeutic frequencies through the cardiac tissue to a subject experiencing arrhythmia. Methods are also provided to minimize or eliminate pain during defibrillation.

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Номер записи: 42
23-08-2012 дата публикации

Method for fabricating an implantable lead for applying electrical pulses to tissue of a patient and system for fabrication thereof

Номер: US20120215339A1
Автор: Jerome Boogaard
Принадлежит: Advanced Neuromodulation Systems Inc

In one embodiment, a method of fabrication an implantable lead for providing electrical pulses to tissue of a patient, the method comprises: (i) providing a sheath of transparent insulative material, wherein the sheath comprises a plurality of lumens; (ii) scanning across the sheath with a confocal displacement meter to generate displacement data; (iii) processing the displacement data, in software executed on a computer system, to generate a representation of an exterior surface and lumens of the sheath; (iv) automatically selecting locations, in software executed on a computer system, on the exterior surface of application of laser pulses to create apertures in the sheath that provide access to respective lumens of the sheath; and (v) applying laser pulses according to the sheath to create the apertures.

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Номер записи: 43
30-08-2012 дата публикации

Stimulating cranial nerve to treat pulmonary disorder

Номер: US20120221087A1
Автор: Albert W. Guzman, Steven E. Maschino, Steven M. Parnis, William R. Buras
Принадлежит: Cyberonics Inc

A method for stimulating a portion of a vagus nerve of a patient to treat a pulmonary disorder is provided. At least one electrode is coupled to at least one portion of a left vagus nerve and/or a right vagus nerve of the patient. An electrical signal is applied to the portion of the vagus nerve using the electrode to treat the pulmonary disorder. The electrical signal may perform a blocking of an intrinsic neural activity on said at least one portion of the left vagus nerve and said right vagus nerve.

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Номер записи: 44
13-09-2012 дата публикации

Radiofrequency Perforation Apparatus

Номер: US20120232546A1
Автор: Gareth Davies, Mahmood Mirza
Принадлежит: Baylis Medical Co Inc

A radiofrequency perforation apparatus for creating a channel at a target location in a body of a patient, the radiofrequency perforation apparatus comprising: a substantially tubular member defining a tubular member lumen; an end member partially positioned within the tubular member lumen at a distal end of the tubular member, the end member including an electrode; and an electrical insulator extending along the substantially tubular member.

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Номер записи: 45
13-09-2012 дата публикации

Automatic baroreflex modulation responsive to adverse event

Номер: US20120232613A1
Автор: David J. Serdar, Matthew M. Burns, Robert S. Kieval
Принадлежит: CVRX Inc

A system for providing baroreflex stimulation comprises a sensor to detect a parameter and provide a signal indicative of the parameter and a baroreflex stimulator. The baroreflex stimulator includes a driver to provide a control signal adapted to deliver a baroreflex therapy and a controller to receive the signal indicative of the parameter and modulate the control signal based on the signal indicative of the parameter to change the baroreflex therapy from a first baroreflex therapy to a second baroreflex therapy.

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Номер записи: 46
13-09-2012 дата публикации

Implantable lead with braided conductors

Номер: US20120232625A1
Автор: Jesse Geroy, John Swoyer, Shahn S. Sage
Принадлежит: Greatbatch Ltd

A therapy delivery element adapted to be implanted into a living body. The therapy delivery element includes an electrode portion with a plurality of electrodes. At least one elongated lead body is attached to the electrode portion. The elongated lead body includes a stylet coil having a stylet coil lumen. The stylet coil extends within the elongated lead body and along at least a portion of the electrode portion. A conductor assembly with a plurality of insulated electrical conductors is braided to extending around the stylet coil and to electrically couple to one or more of the electrodes. The conductor assembly includes an inner lumen with a diameter greater than an outside diameter of the stylet coil. Axial elongation of the elongated lead body reduces the inner diameter of the conductor assembly. A low durometer insulator extends around the conductor assembly. A stylet sized to slide freely within the stylet coil lumen is provided for use during implantation of the therapy delivery element into the living body.

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Номер записи: 47
27-09-2012 дата публикации

Cooling systems for electrode arrays

Номер: US20120245577A1
Автор: Alexander J. Asconeguy, Ricardo D. Roman, Teresa Ann Mihalik, Timothy J. Corvi
Принадлежит: MEDTRONIC ABLATION FRONTIERS LLC

A medical device is disclosed, including a catheter body; an electrode array coupled to the catheter body, the electrode array being transitionable from a substantially linear configuration to a substantially helical configuration; and a fluid conduit coupled to the catheter body spaced apart from the electrode array, wherein the fluid conduit is transitionable from a substantially linear configuration to a substantially helical configuration. The device may include a fluid source in communication with the fluid conduit and a radiofrequency signal generator coupled to the electrode array.

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Номер записи: 48
27-09-2012 дата публикации

Implantable Auditory Prosthesis with Temporary Connector

Номер: US20120245666A1
Автор: Claude Jolly, Thomas Lenarz
Принадлежит: MED EL Elektromedizinische Geraete GmbH

An implantable electrode arrangement for an ear implant system is described. A proximal electrode lead has electrode wires for carrying one or more electrical stimulation signals. A distal electrode array has electrode contacts each forming a terminal end of an electrode wire for applying the electrical stimulation signals to target neural tissue, and one or more intra-operative sensors for generating insertion sensing signals during surgical insertion of the electrode array into the target tissue. An intra-operative electrode section has a sensor connector for providing a temporary connection of one or more external measurement arrangements to the one or more intra-operative sensors during the surgical insertion of the electrode array without being functional after the surgical insertion.

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Номер записи: 49
11-10-2012 дата публикации

Charge balancing for arbitrary waveform generator & neural stimulation application

Номер: US20120259382A1
Автор: Jeffrey A. Weisgarber, Richard J. Polefko, Stephen Trier
Принадлежит: Greatbatch Ltd

A method, device and/or system for generating arbitrary waveforms of a desired shape that can be used for generating a stimulation pulse for medical purposes such as for spinal cord stimulation therapy, where such arbitrary waveforms can also be used for charge balancing purposes.

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Номер записи: 50
11-10-2012 дата публикации

Annular electrode array

Номер: US20120259388A1
Автор: Pedro Galvan-Garcia
Принадлежит: Individual

A three-dimensional annular electrode array (AEA) device is disclosed for use as a cybernetic neural interface for the neural control and sensory feedback of a bionic prosthetic device. The AEA, designed for implantation into a nerve, is comprised of a body ( 6 ) that can be coupled to a sleeve(s) ( 9, 10 ) or a sleeve(s) with a compartmentalized inner core ( 12 ) for connection to the proximal and distal ends of a transected nerve, respectively. Regenerating nerve axons capture and sequester laterally projecting electrode terminals ( 4 ) arranged in radiating clusters ( 5 ) of a plurality of electrode sub-array nodes ( 2 ) that make up the array; connected by a primary electrode lead ( 7 ) to a connector contact array ( 3 ) in a plurality of connectors ( 1 ) for connection to wired or wireless electromechanical systems.

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Номер записи: 51
18-10-2012 дата публикации

Electrical Stimulation Treatment of Hypotension

Номер: US20120265280A1
Автор: BRUCE Simon, JP Errico, Steven Mendez
Принадлежит: ElectroCore Inc

The present invention includes methods and devices for treating hypotension, such as in cases of shock, including septic shock, anaphylactic shock and hypovolemia. The method includes the step of applying at least one electrical impulse to at least one selected region of a parasympathetic nervous system of the patient. The electrical impulse is sufficient to modulate one or more nerves of the parasympathetic nervous system to increase the ratio of blood pressure to heart rate and relieve the condition and/or extend the patient's life.

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Номер записи: 52
25-10-2012 дата публикации

Medical needles and electrodes with improved bending stiffness

Номер: US20120271250A1
Автор: Kimbolt Young
Принадлежит: Boston Scientific Scimed Inc

A device for penetrating tissue includes an elongated element having a distal end, a proximal end, a body extending between the distal and the proximal ends, and a lumen located within at least a portion of the body, wherein the lumen has a cross-sectional shape that is a polygon. A device for penetrating tissue includes an elongated element having a distal end, a proximal end, and a body extending between the distal and the proximal ends, at least a portion of the body having a cross-sectional profile that is a polygon, wherein the elongated element is a cannula.

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Номер записи: 53
25-10-2012 дата публикации

Apparatus and Method for Ablating Tissue

Номер: US20120271334A1
Автор: Benjamin Pless, David A. Gallup, Jack E. Ulstad, Jr., John E. Crowe, Jonathan L. Podmore, Matthias Vaska, Roxanne L. Richman, Scott C. Anderson, Timothy Ciciarelli
Принадлежит: Individual

A control system alters one or more characteristics of an ablating element to ablate tissue. In one aspect, the control system delivers energy nearer to the surface of the tissue by changing the frequency or power. In another aspect, the ablating element delivers focused ultrasound which is focused in at least one dimension. The ablating device may also have a number of ablating elements with different characteristics such as focal length.

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Номер записи: 54
25-10-2012 дата публикации

Electric stimulation device

Номер: US20120271392A1
Автор: Masahiro Onoda, Takuya Uno, Yoshihito Fukui
Принадлежит: Terumo Corp

An electric stimulation device includes a main body portion having a stimulation electrode stimulating nerves or muscles inside the living body, a stimulation circuit portion with a stimulation circuit electrically connected to the stimulation electrode and applying a stimulation signal to the stimulation electrode, and a support body connected to the stimulation circuit portion and holding the implant position of the stimulation electrode inside the living body. The electric stimulation device also includes a fixing body connectable to the base end portion of the main body portion. The fixing body includes a fixing body side coil portion that receives an electromagnetic wave transmitted from an external device. When the fixing body is connected to the main body portion, the fixing body side coil portion is electrically connected to the stimulation circuit to enable power feeding and/or communication with respect to the stimulation circuit in response to the electromagnetic wave.

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Номер записи: 55
01-11-2012 дата публикации

Pacing and Stimulation Apparatus and Methods

Номер: US20120277813A1
Автор: Mark Zdeblick
Принадлежит: Proteus Digital Health Inc

System, device and method of variable pacing and stimulation are provided. In one example device, one or more lead integrated circuits may programmably control one or more variability parameters. One or more electrodes may provide electrical stimulation. Each electrode may be individually addressable by at least one of the lead integrated circuits and controlled by at least one variability parameter. Electrodes may be intentionally shorted together during time intervals that fall between times of stimulus, so as to dissipate potentials that might otherwise persist and cause electrode degradation.

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Номер записи: 56
01-11-2012 дата публикации

Selective stimulation to modulate the sympathetic nervous system

Номер: US20120277839A1
Автор: Daniel H. Kim, Jeffery M. Kramer, Mir A. Imran
Принадлежит: Leland Stanford Junior University, Spinal Modulation LLC

Systems, methods and devices are provided for the targeted treatment of a variety of medical conditions by directly neuromodulating a target anatomy associated with the condition while minimizing or excluding undesired neuromodulation of other anatomies. Typically, the target anatomy includes one or more dorsal root ganglia, dorsal roots, dorsal root entry zones, or portions thereof. Such target stimulation areas are utilized due in part to their effect on the sympathetic nervous system.

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Номер записи: 57
08-11-2012 дата публикации

Temperature Monitoring Return Electrode

Номер: US20120283721A1
Автор: David Gresback, James E. Dunning, Peter Gadsby
Принадлежит: TYCO HEALTHCARE GROUP LP

An electrosurgical return electrode is disclosed. The return electrode includes a first and second flexible conductive material layers and a material layer disposed between the first and second conductive material layers. The material layer is transitionable between a solid state and a non-solid state, the material layer is also configured to melt upon an increase in temperature beyond a predetermined threshold, thereby increasing conductivity between the first and second conductive material layer.

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Номер записи: 58
08-11-2012 дата публикации

Spinal cord stimulation to treat pain

Номер: US20120283797A1
Автор: Dirk De Ridder
Принадлежит: Individual

A system and method for treating pain without paresthesia by spinal cord stimulation.

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Номер записи: 59
15-11-2012 дата публикации

Renal nerve stimulation lead, delivery system, and method

Номер: US20120290053A1
Автор: Cary Hata, Yongxing Zhang
Принадлежит: St Jude Medical LLC

A lead for nerve modulation comprises an elongated body which includes a proximal end, a distal portion having a distal end, and an intermediate portion disposed between the proximal end and the distal portion. The distal portion includes a distal portion anchoring mechanism to anchor the distal portion to a first biological cavity of a patient. The intermediate portion includes an intermediate portion anchoring mechanism to anchor the intermediate portion to a second biological cavity of the patient. The intermediate portion anchoring mechanism is larger in lateral dimension than and is spaced from the distal portion anchoring mechanism. The distal portion and/or the intermediate portion includes a plurality of modulation electrodes. The distal portion anchoring mechanism and/or the intermediate portion anchoring mechanism is configured to position the modulation electrodes to contact tissue of the patient at multiple locations.

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Номер записи: 60
15-11-2012 дата публикации

Implantable Medical Lead

Номер: US20120290056A1
Автор: Gernot Kolberg, Jochen Palm, Klaus Bartels
Принадлежит: Biotronik SE and Co KG

An implantable medical lead for transmitting electrical pulses to excitable bodily tissue and/or signals detected at bodily tissue to a detection and evaluation unit, including a distal electrode or a distal sensor, or actuator; a proximal electrode connector or sensor/actuator connector; and a lead pole which connects the electrode or the sensor or actuator to the electrode connector or sensor/actuator connector and extends in the lead body, wherein the lead pole comprises at least two separate and individually insulated conductors which are electrically interconnected at least at one point which functions as an interchange point, or reversal point, in the lead extension from the proximal electrode or sensor connector to the distal electrode or the distal sensor, and wherein at least one of the separate conductors, in particular close to the reversal point, is interrupted at least once and/or is not connected at one end.

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Номер записи: 61
29-11-2012 дата публикации

Means and Method to Invade Skin, Mucosa, and Underlying Tissues with Little or No Pain

Номер: US20120302956A1
Автор: Pourang Bral
Принадлежит: Individual

A means and a method is disclosed to diminish or eliminate the pain associated with a sharp object penetrating the skin, during such procedures as an injection, biopsy, or deriving a blood sample. To this end, repeated tapping, pressing, or rubbing or vibrating is performed over the skin at or near the site of penetration of the sharp object in conjunction with applying electricity on the skin. The invention discloses a method of using a skin-puncturing means, with enhanced features, to provide local anesthesia at the site of penetration of a sharp object.

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Номер записи: 62
20-12-2012 дата публикации

Method and Apparatus to Perform Electrode Combination Selection

Номер: US20120323291A1
Автор: Alok S. Sathaye, Bruce A. Tockman, M. Jason Brooke
Принадлежит: Cardiac Pacemakers Inc

Approaches for selecting an electrode combination of multi-electrode pacing devices are described. Electrode combination parameters that support cardiac function consistent with a prescribed therapy are evaluated for each of a plurality of electrode combinations. Electrode combination parameters that do not support cardiac function are evaluated for each of the plurality of electrode combinations. An order is determined for the electrode combinations based on the parameter evaluations. An electrode combination is selected based on the order, and therapy is delivered using the selected electrode combination.

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Номер записи: 63
27-12-2012 дата публикации

Device, system, and method for modulating cardiac function

Номер: US20120330092A1
Автор: Akira Shiose, Alex Massiello, Kiyotaka Fukamachi
Принадлежит: CLEVELAND CLINIC FOUNDATION

A therapy delivery device for modulating cardiac function in a subject includes a counterpulsation component, an endovascular lead, and at least one electrode that is physically coupled with the endovascular lead. Each of the counterpulsation component and the endovascular lead includes a proximal end and a distal end. The proximal end of the endovascular lead is physically connected to the distal end of the counterpulsation component.

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Номер записи: 64
27-12-2012 дата публикации

Lead for implantable cardiac prosthesis with integrated protection against the effects of mri fields

Номер: US20120330382A1
Автор: Alaa Makdissi
Принадлежит: SORIN CRM SAS

A lead for an implantable cardiac prosthesis, having an integrated protection against the effects of magnetic resonance imaging (“MRI”) fields. A protection circuit ( 26 ), placed at the distal end of the lead comprises a resistive component ( 28 ) interposed between the electrode (E 1, E 2 ) and the distal end of the conductor ( 22, 24 ) associated with this electrode. A normally-open controlled active switch ( 34, 36 ), allows in its closed state to short-circuit the resistive component. A control stage. ( 32 ) is coupled to the conductors and detects the voltage of a stimulation pulse applied on the conductor(s), and selectively controls by this voltage the closing of the active switch for a duration at least equal to the duration of detected stimulation pulse.

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Номер записи: 65
27-12-2012 дата публикации

System and method for spinal cord stimulation to treat motor disorders

Номер: US20120330391A1
Автор: Dongchul Lee, Kerry Bradley
Принадлежит: Boston Scientific Neuromodulation Corp

A method for using spinal cord stimulation to treat symptoms of motor disorders includes implanting a stimulation lead within a ventral portion of the epidural space. The lead is implanted with at least a portion of the electrodes facing the spinal cord. In a method for providing therapy to a patient suffering from a motor disorder, electrical stimulation energy is applied to at least one ventral column nerve fiber through the implanted stimulation lead. A peripheral region of the patient's body exhibits the symptoms of the motor disorder, and the ventral column nerve fiber to which the stimulation is applied innervates that peripheral region.

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Номер записи: 66
03-01-2013 дата публикации

Method of neurostimulation of distinct neural structures using single paddle lead to treat multiple pain locations and multi-column, multi-row paddle lead for such neurostimulation

Номер: US20130006341A1
Автор: Claudio A. Feler, John H. Erickson
Принадлежит: Individual

In some embodiments, a paddle lead is implanted within a patient such that the electrodes are positioned within the cervical or thoracic spinal levels. An electrode combination on a first row of electrodes can be determined that is effective for a first pain location with minimal effects on other regions of the body. The first pain location can be addressed by stimulating a first dorsal column fiber due to the relatively fine electrical field resolution achievable by the multiple columns. Then, another electrode combination on a second row of electrodes can be determined for a second pain location with minimal effects on other regions. The second pain location could be addressed by stimulating a second dorsal column fiber. After the determination of the appropriate electrodes for stimulation, the patient's IPG can be programmed to deliver pulses using the first and second rows according to the determined electrode combinations.

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Номер записи: 67
10-01-2013 дата публикации

System for heating a vertebral body to treat back pain

Номер: US20130012936A1
Автор: John S. Crombie, Paula Papineau, Richard Pellegrino, Samit Patel, Thomas Ryan
Принадлежит: Relievant Medsystems Inc

Methods and systems for modulating intraosseous nerves (e.g., nerves within bone) are provided. For example, the methods and systems described herein may be used to modulate (e.g., denervate, ablate) basivertebral nerves within vertebrae. The modulation of the basivertebral nerves may facilitate treatment of chronic back pain.

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Номер записи: 68
10-01-2013 дата публикации

Lead system having a non-stationary to stationary electrical interconnect and method therefor

Номер: US20130013046A1
Автор: Eric Falbe Hammill, Eric John Wengreen, Luke Thomas Babler
Принадлежит: Individual

A lead system has an elongate body, an active fixation assembly movable relative to the elongate lead body, including a non-stationary electrode. The lead system further includes a non-stationary electrode member and an electrical interconnect electrically connected between the non-stationary electrode member and the stationary electrode member. The electrical interconnect provides a reliable electrical interconnection between the stationary electrode and the non-stationary electrode, while allowing the non-stationary electrode to move relative to the stationary electrode.

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Номер записи: 69
24-01-2013 дата публикации

Electrode array assembly and method of making same

Номер: US20130023972A1
Автор: Anne M. Pianca, Janusz A. Kuzma
Принадлежит: Boston Scientific Neuromodulation Corp

A lead assembly and a method of making a lead are provided. The method of making a multi-contact lead assembly comprises placing monofilament placed in the void spaces not occupied by the plurality of conductor wires and, in one embodiment, thermally fusing the monofilament to the like material spacer by applying heat just below the melting temperature of the monofilament and spacer material. Alternatively, the monofilament and spacer may be of different materials and heat is applied to cause at least one material to thermally reflow or melt. The conductive contacts may be located at either the distal end and/or proximal end of the lead. Oversized spacers may be used in order to provide extra material to fill voids during the thermal fusion/reflow process.

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Номер записи: 70
31-01-2013 дата публикации

Selection of spinal cord stimulation electrodes for use in cardiac therapy

Номер: US20130030490A1
Автор: Lilian Kornet, Pascalle H.C.M. Reiters, Raphael A. Schneider, Tim D.J. Jongen
Принадлежит: MEDTRONIC INC

Methods, systems, and/or devices for selecting spinal cord stimulation (SCS) electrode array configurations to provide effective cardiac therapy. Physiological parameters related to the heart may be monitored and analyzed during the delivery of SCS using various SCS electrode array configurations to determine an effect SCS electrode array configuration.

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Номер записи: 71
31-01-2013 дата публикации

Method and System for Determining Settings for Deep Brain Stimulation

Номер: US20130030500A1
Автор: David James Anderson, Emil Toader, Franciscus Paulus Maria Budzelaar, Hubert Cécile François MARTENS, Michel Marcel Jose Decre, Pieter Gerrit Blanken
Принадлежит: NeuroNexus Technologies Inc, Sapiens Steering Brain Stimulation BV

A method and a control system ( 20 ) are provided for determining a relation between stimulation settings for a brain stimulation probe ( 10 ) and a corresponding V-field. The brain stimulation probe ( 10 ) comprises multiple stimulation electrodes ( 11 ). The V-field is an electrical field in brain tissue surrounding the stimulation electrodes ( 11 ). The method comprises sequentially applying a test current to n stimulation electrodes ( 11 ), n being a number between 2 and the number of stimulation electrodes ( 11 ) of the brain stimulation probe ( 10 ), for each test current at one of the n stimulation electrodes ( 11 ), measuring a resulting excitation voltage at m stimulation electrodes, m being a number between 2 and the number of stimulation electrodes ( 11 ) of the brain stimulation probe ( 10 ), from the stimulation settings and the measured excitation voltages, deriving an (m*{acute over (η)}) coupling matrix, an element (q, p) in the coupling matrix reflecting an amount of electrical impedance between two of the stimulation electrodes ( 11 ), and using the coupling matrix for determining the relation between the stimulation settings and the corresponding V-field.

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Номер записи: 72
31-01-2013 дата публикации

Method of neurostimulation of distinct neural structures using single paddle lead to treat multiple pain locations and multi-column, multi-row paddle lead for such neurostimulation

Номер: US20130030501A1
Автор: Claudio A. Feler, John H. Erickson
Принадлежит: Advanced Neuromodulation Systems Inc

In some embodiments, a paddle lead is implanted within a patient such that the electrodes are positioned within the cervical or thoracic spinal levels. An electrode combination on a first row of electrodes can be determined that is effective for a first pain location with minimal effects on other regions of the body. The first pain location can be addressed by stimulating a first dorsal column fiber due to the relatively fine electrical field resolution achievable by the multiple columns. Then, another electrode combination on a second row of electrodes can be determined for a second pain location with minimal effects on other regions. The second pain location could be addressed by stimulating a second dorsal column fiber. After the determination of the appropriate electrodes for stimulation, the patient's IPG can be programmed to deliver pulses using the first and second rows according to the determined electrode combinations.

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Номер записи: 73
14-02-2013 дата публикации

Method for coating devices using electrospinng and melt blowing

Номер: US20130041442A1
Автор: Devon N. Arnholt, Douglals D. Pagoria, Jeannette C. Polkinghorne
Принадлежит: Cardiac Pacemakers Inc

A medical electrical lead may include an insulative lead body, a conductor disposed within the insulative lead body, an electrode disposed on the insulative lead body and in electrical contact with the conductor and a fibrous matrix disposed at least partially over the electrode. The fibrous matrix may be formed from a non-conductive polymer.

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Номер записи: 74
14-02-2013 дата публикации

Flexible Protected Lead

Номер: US20130041448A1
Автор: Grahame Walling, Krzysztof Tarrell, Roger Leigh, Scott Henshaw
Принадлежит: Cochlear Ltd

Designs for an implantable lead are disclosed. In one embodiment, the lead includes at least one conductive pathway and a protective element surrounding at least a portion of the at least one conductive pathway. A stiffness of the protective element varies along a length of the protective element. The stiffness may be varied by varying a material composition of the protective element. Alternately, the protective element may be one or two helically-wound wires, and the stiffness may be varied by varying a pitch of one or both helically-wound wires. Alternately, the protective element may be a perforated tube and the stiffness may be varied by varying a ratio of openings to tube in the perforated tube. Alternately, the protective element may be a patterned mesh and the stiffness may be varied by varying a pattern of the patterned mesh. The implantable lead may be used in a cochlear implant.

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Номер записи: 75
21-02-2013 дата публикации

Apparatuses and systems for generating high-frequency shockwaves, and methods of use

Номер: US20130046207A1
Автор: Christopher C. Capelli
Принадлежит: University of Texas System

Apparatuses and methods for generating therapeutic shock waves. Some embodiments comprise: an acoustic-wave generator configured to emit acoustic waves having at least one frequency between 1 MHz and 1000 MHz; a shock wave housing coupled to the acoustic-wave generator; and a shock wave medium disposed in the shock wave housing; where the apparatus is configured such that if the acoustic-wave generator emits acoustic waves then at least some portion of the acoustic waves will travel through the shock wave medium and form one or more shock waves.

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Номер записи: 76
21-02-2013 дата публикации

Cardiac Electrosurgery

Номер: US20130046305A1
Автор: Gareth Davies
Принадлежит: Baylis Medical Co Inc

Devices and methods are disclosed for providing access to the pericardial cavity while reducing risk of myocardial damage. The methods include maintaining the positions of a puncture device and of a portion of a parietal pericardium relative to one other while delivering energy from the puncture device to create a channel through the pericardium. Additional embodiments disclosed include delivering a pulse or pulses of energy to the parietal pericardium and attempting to advance the puncture device through the parietal pericardium between deliveries of energy pulses.

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Номер записи: 77
21-02-2013 дата публикации

Multi-Area Pacing Lead For A Left Cavity Of The Heart, Implantable In The Coronary Network

Номер: US20130046370A1
Автор: Frédéric Anselme, Jean-Francois Ollivier, Nicolas Shan
Принадлежит: SORIN CRM SAS

A multi-area pacing lead implantable in a target vein of the coronary network for stimulating a left cavity of the heart, comprising an electrically conductive microcable ( 12 ), an electrically insulating outer coating, and carrying at its distal end a free active portion containing a plurality of separate denuded areas forming a network of active stimulation electrodes ( 14, 16 ), intended to contact the wall of target veins. The active free portion has a proximal corrugated portion carrying a first set of electrodes ( 14 ), a distal corrugated portion carrying a second series of electrodes ( 16 ) and an intermediate portion ( 20 ) that traverses an anastomosis ( 22 ) connecting the ends of two veins (VA, VPL). Both sets of electrodes ( 14, 16 ) can thus be placed in two different veins, defining two remote stimulation areas.

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Номер записи: 78
28-02-2013 дата публикации

Dipole electrical stimulation employing direct current for recovery from spinal cord injury

Номер: US20130053922A1
Автор: Andrzej Wieraszko, Zaghloul Ahmed
Принадлежит: Individual

A system and method to treat neuromuscular conditions, including spinal cord injury, by what is characterized as dipole (two point) cortico-muscular stimulation. Two-point stimulation, with oppositely charged electrodes, allows pulsed, direct current to pass through the cortico-muscular pathway. The electrodes are placed on nerves, muscles, or a combination of both, that are on opposite sides of the spinal column, forming a current that passes across the spinal column. Further, an active electrode can be placed on the spinal column and a reference electrode can be placed outside the central nervous system. These methods improve functional recovery of the motor pathway.

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Номер записи: 79
07-03-2013 дата публикации

Multi-actuator array for the specific deformation of an implant

Номер: US20130060260A1
Автор: Omid Majdani, Sonja Dudziak, Thomas Lenarz, Thomas Rau
Принадлежит: Individual

An electronic control device assists in the insertion of an implant into the body of a patient, and allows the implant to be arbitrarily altered in shape by applying control signals. Patient-specific geometric body data from a body region into which the implant is to be introduced is input and stored. Computer-aided simulation of the insertion operation uses the patient-specific body data as a basis for simulating the insertion operation to produce actuation data which control the arbitrary alteration in the shape of the implant. The control device outputs the actuation data to the implant in the form of control signals on the basis of a sensed or calculated current introduction position of the implant according to the prior simulation.

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Номер записи: 80
07-03-2013 дата публикации

Neural prosthesis and method for producing a neural prosthesis

Номер: US20130060266A1
Автор: Georg Bretthauer, Selman Uranues
Принадлежит: Karlsruher Institut fuer Technologie KIT, MEDIZINISCHE UNIVERSITAET GRAZ

The invention relates to a neural prosthesis, a neural prosthesis for use in the treatment of severed nerves and to a method for producing a neural prosthesis. Said neural prosthesis comprises a coupling element receptacle and at least one coupling element having a first and a second coupling section, wherein the coupling element is fixed by the coupling element receptacle, and wherein the first coupling section can be arranged on a first nerve region and the second coupling section on a second nerve region so that both nerve regions can be coupled by means of the neural prosthesis.

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Номер записи: 81
07-03-2013 дата публикации

Surgical lead paddle

Номер: US20130060313A1
Автор: Thomas E. Cross, Jr.
Принадлежит: MEDTRONIC INC

The present invention provides for an improved apparatus and method for electrical stimulation. A paddle having a thickness up to 0.030 inches is implanted adjacent the spinal cord dura mater to reduce the likelihood of paralysis due to stress on the spinal cord attributed to bulkier leads. The paddle is then positioned so that at least one of a plurality of electrodes is positioned over the area of the spinal cord requiring pain treatment; and then electric stimulation is applied to the electrodes to effect pain treatment. In another embodiment the paddle is curved about a vertical axis to substantially match the shape of a human spinal cord dura mater to help reduce lead migration.

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Номер записи: 82
14-03-2013 дата публикации

Tibial nerve stimulation

Номер: US20130066393A1
Автор: Ali STERN-COHEN, Danny Neeman, Gur Oron, Noam Kinrot, Shlomo Ronen, Yossi Gross
Принадлежит: Rainbow Medical Ltd

A method is provided, including identifying a subject as suffering from pain in a first limb of the subject. In response to the identifying, treatment of the pain in the first limb is facilitated by implanting electrodes in a limb of the subject that is contralateral to the first limb. Other embodiments are also described.

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Номер записи: 83
21-03-2013 дата публикации

IMPLANTABLE AND RECHARGEABLE NEURAL STIMULATOR

Номер: US20130073000A1
Автор: Caparso Anthony V., Chavan Abhi V., Scheiner Avram
Принадлежит:

One aspect of the present subject matter relates to an implantable medical device. An embodiment of the device comprises a rechargeable power supply adapted to be recharged through an ultrasound signal, a neural stimulator connected to the rechargeable power supply, and a controller connected to the rechargeable power supply. The neural stimulator is adapted to generate a neural stimulation signal for delivery to a neural stimulation target through an electrode. The controller is further connected to the neural stimulator to control the neural stimulator according to a neural stimulation protocol. Other aspects are provided herein. 1. A system for therapeutically stimulating a neural stimulation target of a human , comprising:an implantable medical device, wherein the implantable medical device includes a neural stimulator configured to deliver neural stimulation for use in stimulating the neural stimulation target, the implantable device including an ultrasound transducer configured to convert an ultrasound energy into an electrical energy,wherein the implantable medical device is configured to power the neural stimulator using the electrical energy converted from the ultrasound energy.2. The system of claim 1 , wherein the implantable medical device is remotely powered through the ultrasound energy.3. The system of claim 1 , wherein the ultrasound power signal includes data encoded within the ultrasound power signal claim 1 , wherein the implantable device is further configured to receive and process the data encoded in the ultrasound power signal.4. The system of claim 1 , further comprising an external device configured to send the ultrasound energy.5. The system of claim 1 , further comprising another implantable device configured to send the ultrasound energy.6. The system of claim 1 , wherein the implantable medical device further comprises:a blood pressure sensor configured to sense blood pressure; anda controller configured to control the neural stimulator ...

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Номер записи: 84
21-03-2013 дата публикации

METHOD AND APPARATUS FOR A SMALL POWER SOURCE FOR AN IMPLANTABLE DEVICE

Номер: US20130073004A1
Автор: Maile Keith R., Root Michael J., Youker Nick A.
Принадлежит:

One example includes a battery that includes a stack of at least one substantially planar anode and at least one substantially planar cathode, wherein the stack defines a contoured exterior, and a battery housing enclosing the stack, the battery housing defining a battery housing exterior, wherein the contoured exterior of the stack is shaped to conform to a contoured interior of the battery housing that approximately conforms to the battery housing exterior, the battery produced by the process of modeling, using fluid dynamics, an exterior of a biocompatible housing and shaping the battery housing to conform to at least some of the exterior of the biocompatible housing. 1. An apparatus , comprising:an implantable electronics shell;electronics disposed in the implantable electronics shell;an implantable power source shell defining an implantable power source shell interior, the implantable power source shell being hermetically sealed to the implantable electronics shell with a first seal, with the electronics disposed outside the implantable power source shell; an annular anode connected to a first terminal; and', 'a cathode connected to a second terminal and disposed around the anode,', 'wherein the anode and the cathode are arranged in a bobbin configuration,, 'a power source disposed in the implantable power source shell interior, the power source being sealed in the implantable power source shell with a second seal, the power source comprisingwherein an exterior of the apparatus includes an exterior of the implantable electronics shell and an exterior of the implantable power source shell.2. The apparatus of claim 1 , wherein the electronics shell and the power source shell are cylindrical.3. The apparatus of claim 2 , wherein the electronics shell and the power source shell are arranged in a column.4. The apparatus of claim 1 , wherein the implantable power source shell defines an implantable power source shell exterior shaped using modeled fluid dynamics and ...

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Номер записи: 85
21-03-2013 дата публикации

Systems and methods for adjusting electrical therapy based on impedance changes

Номер: US20130073007A1
Автор: Andre B. Walker, Jon Parker, Udal Singh
Принадлежит: Nevro Corp

System and methods for adjusting electrical therapy based on impedance changes are disclosed herein. A method in accordance with a particular embodiment includes applying a therapeutic electrical signal to a patient via an implanted portion of a patient stimulation system that includes a signal delivery device in electrical communication with a target neural population of the patient. The electrical signal is delivered in accordance with a signal delivery parameter having a first value. Using the implanted portion of the patient stimulation system, a change in an impedance of an electrical circuit that includes the signal delivery device is detected. Based at least in part on the detected impedance change, the method can further include automatically adjusting the value of the signal delivery parameter from the first value to a second value different from the first, without human intervention.

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Номер записи: 86
21-03-2013 дата публикации

BAND STOP FILTER EMPLOYING A CAPACITOR AND AN INDUCTOR TANK CIRCUIT TO ENHANCE MRI COMPATIBILITY OF ACTIVE MEDICAL DEVICES

Номер: US20130073021A1
Автор: Frysz Christine A., Halperin Henry R., Kondabatni Kishore Kumar, Stevenson Robert A.
Принадлежит: Greatbatch Ltd.

An implantable lead includes a lead conductor having a length extending from a proximal end to a distal end. A self-resonant inductor is connected in series along a portion of the length of the lead conductor. The self-resonant inductor includes a single length of conductive material including a dielectric coating substantially surrounding the single length of conductive material. The self-resonant inductor includes a first coiled or spiral conductor disposed along an inductor section spanning in a first direction from a first location to a second location. A second coiled or spiral conductor is disposed along the inductor section spanning in a second direction from the second location to the first location, where the second direction is opposite the first direction. A third coiled or spiral conductor is disposed along the inductor section spanning in the first direction from the first location to the second location. 1. An implantable lead configured to be permanently or removably connectable to an active implantable medical device , comprising:a lead conductor having a length extending from a proximal end to a distal end; andan insulated and self-resonant inductive coil connected in series along a portion of length of the lead conductor, wherein the inductive coil comprises a parasitic capacitance between its adjacent turns such that the inductive coil becomes self-resonant at a selected center frequency or across a range of frequencies about the selected center frequency.2. The lead of claim 1 , wherein the selected center frequency comprises an MRI RF pulsed frequency.3. The lead of claim 2 , wherein the insulated and self-resonant inductive coil comprises a tank filter performance.4. The lead of claim 3 , wherein the tank filter performance attenuates the MRI RF pulsed frequency.5. The lead of claim 4 , wherein the self-resonant inductive coil has an inductance with an associated resistance and a parasitic capacitance with an associated resistance which ...

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Номер записи: 87
28-03-2013 дата публикации

METHODS AND SYSTEMS FOR GLUCOSE REGULATION

Номер: US20130079745A1
Автор: Knudson Mark B., Thornton Arnold W., Tweden Katherine S., Wilson Richard R., Wong-won Dennis Kim
Принадлежит: EnteroMedics, Inc.

Various methods and apparatus for treating a condition associated with impaired glucose regulation in a subject comprising in one embodiment, applying a neural conduction block to a target nerve at a blocking site with the neural conduction block selected to at least partially block nerve pulses. In another embodiment, combinations of down-regulating and or up-regulating with or without pharmaceutical agents are used to treat impaired glucose regulation. In other embodiments, up-regulation or down-regulation of various nerves, such as the vagus and its branches, and the splanchnic is used to modify the production of GLP-1 and GIP, thereby controlling glucose levels. In yet further embodiments, combinations of down-regulating and or up-regulating with or without pharmaceutical agents are used to modify the production of GLP-1 and GIP, to treat impaired glucose regulation. 1. A method of modifying the amount of GLP1 , GIP , or both comprising:applying a first intermittent electrical signal to a target nerve with said electrical signal selected to upregulate or down-regulate neural activity on the nerve and to restore neural activity on the nerve upon discontinuance of said signal, wherein the electrical signal is selected to modify the amount of GLP1, GIP, or both.2. The method according to claim 1 , wherein the electrical signal is selected to increase GLP1.3. The method of claim 1 , wherein the first electrical signal is applied intermittently in a cycle including an on time of application of the signal followed by an off time during which the signal is not applied to the nerve claim 1 , wherein the on and off times are applied multiple times per day over multiple days.4. The method of claim 3 , wherein the on time is selected to have a duration of about 30 seconds to about 5 minutes.5. The method according to claim 1 , wherein the electrical signal is applied at a frequency of about 1 Hz to 5000 Hz.6. The method according to claim 1 , wherein the electrical signal ...

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Номер записи: 88
28-03-2013 дата публикации

ELECTRODE ARRANGEMENT

Номер: US20130079862A1
Автор: ELLRICH Jens
Принадлежит: CERBOMED GMBH

The invention relates to an electrode arrangement to be attached on and/or in the ear of a human, wherein the electrode arrangement is designed to exert a transcutaneous electric stimulation stimulus onto the surface of the ear and wherein the electrode arrangement has at least one stimulation electrode and at least one reference electrode. In order to achieve an improved transcutaneous stimulation, especially of the Vagus nerve, the invention provides that the at least one stimulation electrode contacts the surface of the ear via a first contact surface and that the at least one reference electrode contacts the surface of the ear via a second contact surface, wherein the second contact surface is at least three time the size of the first contact surface. 1. An electrode arrangement to be attached on and/or in the ear of a human , wherein the electrode arrangement is designed to exert a transcutaneous electric stimulation stimulus onto the surface of the ear , the electrode arrangement comprising:at least one stimulation electrode and at least one reference electrode,wherein the at least one stimulation electrode has an arcuated structure and contacts the surface of the ear via a first contact surface,wherein the at least one reference electrode has an oval or drused structure and contacts the surface of the ear via a second contact surface,wherein the second contact surface is at least three times the size of the first contact surface,wherein at least one of the electrodes contacts the surface of the ear via a contact surface, wherein the electrode is so designed that it covers at least 50% of the surface of the Cymba conchae of the ear.2. The electrode arrangement of claim 1 , wherein the second contact surface is at least five times the size of the first contact surface.3. The electrode arrangement of claim 1 , wherein the at least one stimulation electrode acts as a cathode and the at least one reference electrode as an anode in the electrical circuit which is ...

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Номер записи: 89
04-04-2013 дата публикации

APPARATUS AND METHODS FOR IMPLANT COUPLING INDICATION

Номер: US20130085537A1
Автор: Mashiach Adi
Принадлежит:

A device is disclosed that includes an external unit configured to communicate with an implant unit beneath the skin of a subject and an indicator associated with the external unit. The indicator is configured to produce an indicator signal when the external unit is within a predetermined range of the implant unit. In addition, the indicator may be configured to vary the indicator signal according to a distance between the external unit and the implant unit. Furthermore, a method of locating an external unit with respect to an implant unit is disclosed that includes detecting a distance between the external unit and the implanted unit located beneath the skin of a subject, producing an indicator signal when the external unit is within a predetermined range of the implant unit, and varying the indicator signal as a function of a distance between the external unit and the implant unit. 1. A sleep apnea treatment device , comprising:an external unit configured for location on a neck of a subject to communicate with an implant unit implanted proximal to a tongue of a subject; andan indicator associated with the external unit, wherein the indicator is configured to produce an indicator signal when the external unit is within a predetermined range of the implant unit, and wherein the indicator is configured to vary the indicator signal according to a distance between the external unit and the implant unit.2. The sleep apnea treatment device of claim 1 , wherein the indicator signal includes an electrical signal communicated to the implant unit claim 1 , the electrical signal causing the implant unit to modulate a hypoglossal nerve and to induce at least one of a proprioceptive or kinesthesic reaction in the tongue of the subject.3. The sleep apnea treatment device of claim 1 , wherein the external unit comprises at least one processor; the at least one processor being configured to:generate a primary signal on a primary antenna associated with the external unit, the ...

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Номер записи: 90
04-04-2013 дата публикации

Devices and Methods for Low Current Neural Modulation

Номер: US20130085561A1
Автор: Mashiach Adi
Принадлежит:

A device may include an implantable circuit and at least one pair of implantable electrodes, in electrical communication with the implantable circuit. The circuit and the electrodes may configured for implantation in a subject in the vicinity of a nerve. The circuit may be configured to deliver to the electrodes an electrical signal having a current less than about 1.6 milliamps, and the electrodes may be configured to emit an electric field such that a portion of the field lines extend along a length of the nerve such that the delivery of the electrical signal of less than about 1.6 milliamps causes modulation of the nerve. 1. A sleep disordered breathing treatment device , comprising:an implantable circuit;at least one pair of implantable electrodes, electrically connected with the implantable circuit, wherein the circuit and the electrodes are configured for implantation in a subject proximal to a genioglossus muscle in the vicinity of a hypoglossal nerve; andwherein the circuit is configured to deliver to the electrodes an electrical signal having a current less than about 1.6 milliamps, andwherein the electrodes are configured to emit an electric field such that a portion of the field lines extend along a length of the hypoglossal nerve such that the delivery of the electrical signal of less than about 1.6 milliamps causes modulation of the hypoglossal nerve.2. The sleep disordered breathing treatment device of claim 1 , wherein the circuit is configured to deliver a plurality of electrical signals to the electrodes claim 1 , and wherein each of the plurality of electrical signals has a current less than about 1.6 milliamps.3. The sleep disordered breathing treatment device of claim 2 , wherein the plurality of electrical signals include various voltage levels claim 2 , current levels claim 2 , or durations.4. The sleep disordered breathing treatment device of claim 1 , wherein the implantable circuit is configured to receive energy from a source external to a ...

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Номер записи: 91
11-04-2013 дата публикации

IMPLANTABLE MICRO-COMPONENT ELECTRODES

Номер: US20130090542A1
Автор: Deng Xiaopei, Kipke Daryl R., KOTOV Nicholas A., Kozai Takashi Daniel Yoshida, Lahann Joerg, Langhals Nick, PATEL Paras
Принадлежит: THE REGENTS OF THE UNIVERSITY OF MICHIGAN

The present disclosure provides robust implantable micro-component electrodes that can be used in a variety of medical devices. The medical device may be a neural probe that can monitor or stimulate neural activity in an organism's brain, spine, nerves, or organs, for example. The micro-component electrode has a small physical profile, with ultra-thin dimensions, while having high strength and flexibility. The micro-electrode has an electrically conductive core material, e.g., carbon. The surface of the core material includes one or more electrically conductive regions coated with an electrically conductive material and one or more non-conductive regions having an electrically non-conductive biocompatible polymeric coating. Implantable devices having such micro-components are capable of implantation in an organism for very long durations. 1. An implantable micro-component electrode comprising:an electrically conductive core material;one or more electrically conductive regions disposed on the surface of the electrically conductive core material comprising an electrically conductive biocompatible coating;an electrically non-conductive biocompatible coating disposed on regions of the surface of the electrically conductive core material where the one or more electrically conductive regions are absent, wherein the micro-component electrode has at least one dimension of less than or equal to about 10 μm.2. An implantable micro-component electrode of claim 1 , wherein the electrically conductive core material that has an elastic tensile modulus of greater than or equal to about 200 GPa and a nominal value of stiffness of greater than or equal to about 5 GN/μm and the electrically non-conductive biocompatible coating has a thickness of less than 1 μm.3. The implantable micro-component electrode of claim 1 , wherein the electrically conductive core comprises carbon.4. The implantable micro-component electrode of claim 3 , wherein the electrically conductive core is selected ...

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Номер записи: 92
11-04-2013 дата публикации

Renal nerve ablation cooling device and technique

Номер: US20130090650A1
Автор: Mark L. Jenson, Scott R. Smith, Travis J. SCHAUER
Принадлежит: Boston Scientific Scimed Inc

A catheter is disclosed including an elongated shaft having a distal end and a proximal end, where the catheter includes a thermal element at the distal end thereof. The thermal element may be used in an ablation procedure or other procedure to heat a tissue adjacent a vessel. The configuration of the distal end of the elongated shaft at or near the distal tip may encourage the cooling of or transferring of heat from the vessel wall. The configurations may include protrusions extending from and indentations extending into the shaft, which may manipulate the flow of fluid through a vessel in which the catheter has been inserted. Alternatively or additionally, a cap or thin insulative layer may be placed at or near the distal tip of the catheter shaft to cool the wall of the vessel.

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Номер записи: 93
18-04-2013 дата публикации

Modeling positions of implanted devices in a patient

Номер: US20130096642A1
Автор: Brett Wingeier
Принадлежит: Nevro Corp

Technology is disclosed for modeling positions of implanted devices in a patient. In various embodiments, the technology can construct a forward model that predicts an electrical impedance between electrical contacts; detects an actual electrical impedance between electrical contacts; computes a fitness value based on a comparison between the detected electrical impedance and the predicted electrical impedance; varies at least one parameter of the forward model until the computed fitness value is a maximum fitness value; and displays at a display device a estimated position of the first lead and/or second leads.

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Номер записи: 94
18-04-2013 дата публикации

MULTI-FREQUENCY NEURAL TREATMENTS AND ASSOCIATED SYSTEMS AND METHODS

Номер: US20130096643A1
Автор: Alataris Konstantinos, Caparso Anthony V., Erickson Brian J., Fang Zi-Ping, Walker Andre B.
Принадлежит: Nevro Corporation

Multi-frequency neural treatments and associated systems and methods are disclosed. A method in accordance with a particular embodiment includes at least reducing patient pain by applying a first electrical signal to a first target location of the patient's spinal cord region at a frequency in a first frequency range of up to about 1,500 Hz, and applying a second electrical signal to a second target location of the patient's spinal cord region at a frequency in a second frequency range of from about 2,500 Hz to about 100,000 Hz. 1. A method for alleviating patient pain or discomfort , comprising:applying or instructing application of a high frequency blocking signal to the dorsal column of the patient,wherein the high frequency blocking signal is at a frequency in a frequency range of from about 2,500 Hz to about 100,000 Hz, andwherein the high frequency blocking signal inhibits or prevents the patient's sensation of pain without using paresthesia to mask the patient's sensation of pain.2. A method for alleviating patient pain or discomfort , comprising:applying or instructing application of a low frequency stimulation signal to the patient's spinal cord region, wherein the low frequency stimulation signal is at a frequency in a first frequency range of from about 40 Hz to about 500 Hz, and wherein the low frequency stimulation signal induces paresthesia to mask the patient's sensation of pain; andapplying or instructing application of a high frequency blocking signal to the patient's spinal cord region, wherein the high frequency blocking signal is at a frequency in a second frequency range of from about 2,500 Hz to about 100,000 Hz, and wherein the high frequency blocking signal alleviates the patient's discomfort resulting from the paresthesia.3. The method of claim 1 , wherein the frequency range is from about 2 claim 1 ,500 Hz to about 20 claim 1 ,000 Hz.4. The method of claim 1 , wherein the frequency range is from about 3 claim 1 ,000 Hz to about 10 claim 1 , ...

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Номер записи: 95
18-04-2013 дата публикации

Multi-frequency neural treatments and associated systems and methods

Номер: US20130096644A1
Автор: Andre B. Walker, Anthony V. Caparso, Brian J. Erickson, Konstantinos Alataris, Zi-Ping Fang
Принадлежит: Nevro Corp

Multi-frequency neural treatments and associated systems and methods are disclosed. A method in accordance with a particular embodiment includes at least reducing patient pain by applying a first electrical signal to a first target location of the patient's spinal cord region at a frequency in a first frequency range of up to about 1,500 Hz, and applying a second electrical signal to a second target location of the patient's spinal cord region at a frequency in a second frequency range of from about 2,500 Hz to about 100,000 Hz.

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Номер записи: 96
18-04-2013 дата публикации

Battery Ventilation for a Medical Device

Номер: US20130096646A1
Автор: Duftner Alexander, Jamnig Bernhard, Yildirim Altan
Принадлежит: MED-EL Elektromedizinische Geraete GmbH

A medical device is presented that includes an external portion adapted for placement external to the skin of a user. The external portion includes a battery pack for interfacing with at least one battery cell. The battery pack includes a housing, the housing defining air inlet and/or outlet holes such that fluid flow is enabled through at least a part of the housing. A micro-ventilation mechanism moves air through at least a part of the housing. 1. A medical device comprising: a housing, the housing defining air inlet and/or outlet holes such that fluid flow is enabled through at least a part of the housing; and', 'a micro-ventilation mechanism for moving air through at least a part of the housing., 'a battery pack for interfacing with at least one battery cell, the battery pack including, 'an external portion adapted for placement external to the skin of a user, the external portion including2. The medical device according to claim 1 , further comprising an implantable portion that receives a signal from the external portion.3. The medical device according to claim 2 , wherein the external portion includes a first coil claim 2 , and wherein the implantable portion includes a second coil claim 2 , the first coil and the second coil for transcutaneous transmission of the signal via electromagnetic coupling.4. The medical device according to claim 3 , wherein the battery pack supplies a power signal to the first coil claim 3 , for transcutaneous transmission to the second coil.5. The medical device according to claim 2 , wherein the implantable portion includes a stimulator module for producing for the auditory system of a user a stimulation representative of an acoustic signal.6. The medical device according to claim 5 , wherein the stimulation is an electrical stimulation and/or a mechanical stimulation.7. The medical device according to claim 2 , wherein the implantable portion includes one of a laryngeal pacemaker claim 2 , a middle-ear implant and a cochlear ...

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Номер записи: 97
18-04-2013 дата публикации

Package for an Implantable Device

Номер: US20130096661A1
Автор: Joseph H. Schulman, Robert Greenberg
Принадлежит: Second Sight Medical Products Inc

The present invention is an implantable electronic device formed within a biocompatible hermetic package. Preferably the implantable electronic device is used for a visual prosthesis for the restoration of sight in patients with lost or degraded visual function. The package is formed from a thin film of hermetic biocompatible material to minimize the size of the implanted device.

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Номер записи: 98
18-04-2013 дата публикации

ATRAUMATIC LEAD REMOVAL SHEATH

Номер: US20130096663A1
Автор: Cully Edward H., Duncan Jeffrey B., Hopkinson Aaron J., Vonesh Michael J.
Принадлежит: W. L. Gore & Associates, Inc.

The present invention provides for a safer and less traumatic chronically implanted device and methods for removing same from a patient. One embodiment of the invention provides for a medical device comprising an implantable diagnostic or therapeutic lead having a distal end, a proximal end, a longitudinal axis and an outer surface, and a tubular cover attached to the diagnostic or therapeutic lead, preferably near the distal end, and positioned to cover a substantial portion of the outer surface of the diagnostic or therapeutic lead. The tubular cover is configured to evert upon application of a longitudinal force to extract the diagnostic or therapeutic lead. 1. A medical device comprising a tubular cover , the tubular cover configured to evert upon application of a longitudinal force to the medical device following implantation.2. The medical device of claim 1 , wherein the medical device is chronically implanted in an animal.3. The medical device of claim 2 , wherein the medical device is prone to tissue incorporation.4. The medical device of claim 1 , wherein the medical device is selected from the group consisting of lead generators claim 1 , arteriovenous (A-V) access catheters claim 1 , peripherally inserted central (PICC) catheter lines claim 1 , venous feeding catheters claim 1 , breathing tubes claim 1 , and implanted sensing devices.5. The device of claim 1 , wherein the tubular cover comprises ePTFE.6. The device of claim 5 , wherein the ePTFE comprises at least one additive.7. The device of claim 6 , wherein the additive is a lubricating agent.8. The device of claim 6 , wherein only a portion of the tubular cover comprises an additive.9. The device of claim 6 , wherein the additive elicits a bioactive response.10. The device of claim 9 , wherein the bioactive response is selected from the group consisting of an anti-inflammatory claim 9 , anti-microbial claim 9 , and an anti-proliferative response.11. The device of claim 5 , wherein the tubular cover ...

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Номер записи: 99
25-04-2013 дата публикации

Methods, Tools, and Assemblies for Implantation of Medical Leads Having Distal Tip Anchors

Номер: US20130103049A1
Автор: Eric H. Bonde
Принадлежит: MEDTRONIC INC

Medical leads include distal tip anchors that are retained by fixation mechanisms of implantation tools. The fixation mechanism may include a fixed body that has features retaining the distal tip anchor. The fixation mechanism may include a movable body that can apply tension to the distal tip anchor to force the distal tip anchor to be released from the features of the fixed body. The movable body may include an axial portion that is received by an axial hole of the fixed body to allow for axial movement of the movable body to release the distal tip anchor. The fixation mechanism may instead include an elongated flexible body that passes through the distal tip anchor and is attached to the fixed body. Tension applied to the elongated body creates a releasing motion of the distal tip anchor to free the distal tip anchor from the features of the fixed body.

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Номер записи: 100