TOOLS OF INSTALLATION OF CASING HAVE KEY AND KIT INCLUDING/UNDERSTANDING THIS ONE

ORGAN PRESERVATIVE COMPOSITION AND USES THEREOF

COMPOSITION OF SAFEGUARDING Of BODY AND USES

L'invention se rapporte à l'utilisation d'une composition comprenant au moins une globine, un protomère de globine ou une hémoglobine extracellulaire d'Annélides, une solution de stabilisation et/ou une solution de conservation d'organes, ladite composition ayant une température comprise entre 0°C et 37°C, pour préserver un organe chez un donneur décédé en état de mort cérébrale ou décédé d'arrêt cardiaque. L'invention se rapporte également à un procédé de conservation d'un organe in situ dans un donneur décédé en état de mort cérébrale ou décédé d'arrêt cardiaque à l'aide des techniques CRN ou sonde de Gillot ou toute autre technique similaire. The invention relates to the use of a composition comprising at least one globin, a globin protomer or an extracellular Annelides hemoglobin, a stabilizing solution and / or an organ preservation solution, said composition having a temperature between 0 ° C and 37 ° C, to preserve an organ in a donor who died in a brain dead or died of cardiac arrest. The invention also relates to a method of preserving an organ in situ in a deceased donor in a brain dead or died state of cardiac arrest using CRN or Gillot probe techniques or any other similar technique.

LYOPHILIZATION METHOD ANNELIDES OF HEMOGLOBIN

LOCKING SYSTEM FOR PREVENTING THE BACKWARD UNLOCKING

Use of globin, globin protomer and/or native hemoglobin, naturally extracellular, invertebrate animal, in combination with organ preservative solution, or cell culture medium, to constitute composition e.g. for organ/tissue preservation

Use of a globin and/or globin protomer and/or a native hemoglobin, naturally extra cellular, invertebrate animal comprising phylum Annelida, belonging to marine worms comprising Arenicola marina, at a concentration of 0.625-100 mg/ml, preferably 1.25 mg/ml, in combination with organ preservative solution, or a cell culture medium, for constituting a composition for organ, tissue or cells of organs or tissue preservation, for perfusion of organ or tissues, or for the culture of organ cells or tissues, is claimed. Independent claims are included for: (1) a composition comprising the globin and/or globin protomer and/or the extracellular hemoglobin and the organ preservation solution; (2) a process for preserving the organ or tissue or cells of organ or tissue, preferably organ, comprising rinsing the organ or tissue previously collected, at a temperature of 4-37[deg] C, preferably 4[deg] C, with the composition, and preserving of the organ or tissue by static or dynamic perfusion at a temperature of 4-37[deg] C, preferably 4[deg] C, for a determined time, according to the organ or tissue, in the composition; (3) a process for culturing the organ cells or tissue cells from the organs of vertebrates, comprising culturing the cells, previously collected from vertebrate, at a temperature of 4-37[deg] C, preferably 37[deg] C, for a specified period, depending on the cells, in the composition, and collecting the cells by washing and lysis of the cell mat; and (4) a process for culturing the organ cells or tissue cells from invertebrates, comprising collecting the cells of invertebrate, culturing at a temperature of 4-37[deg] C, preferably 4[deg] C, for a fixed time, depending on the cells in the composition, and collecting the cells by washing and lysis of the cell mat.

Package for hooks of elongated shape, in particular holding hooks of slate on roofs.

USE OF A HAEMOGLOBIN FOR THE PREPARATION OF WOUND DRESSINGS, AND RESULTING DRESSINGS

PROCEEDED OF REACTIVE PULVERIZATION HAS CYCLIC CONTROL SIGNAL AND CORRESPONDING DEVICE.

METHOD FOR GEOLOCATING A RADIO TRANSMITTER

L'invention concerne un procédé de géolocalisation d'un dispositif émetteur de signal, le procédé de géolocalisation comportant : a. Fournir des positions d'une pluralité de stations et des dates de réception du signal radio par lesdites stations, b. Sélectionner une station de référence, c. Définir une zone de balayage, d. Subdiviser la zone de balayage en fonction d'une granularité de balayage, e. Pour chaque sous-zone, calculer un degré d'erreur cumulée de ladite sous-zone, f. sélectionner une sous-zone présentant un degré d'erreur cumulé minimal, g. définir une nouvelle zone de balayage, h. définir une nouvelle granularité de balayage, i. itérer le procédé à partir de l'étape d). The invention relates to a method of geolocation of a signal-emitting device, the geolocation method comprising: a. Providing positions of a plurality of stations and dates of reception of the radio signal by said stations, b. Select a reference station, c. Define a scan area, d. Subdivide the scan area according to a scanning granularity, e. For each subfield, calculate a cumulative error degree of said subfield, f. select a subfield with a minimum accumulated degree of error, g. define a new scan area, h. define a new scanning granularity, i. iterate the process from step d).

MANUFACTORING PROCESS Of a MAGNET MOULDS.

Procédé de fabrication d'un aimant moulé comprenant des opérations de réalisation d'un premier et un deuxième tronçon de corps magnétiques, puis une opération assemblage des premier et deuxième tronçons de corps. L'opération de réalisation d'un tronçon de corps comprend une étape d'injection dans une cavité d'un dispositif de moulage d'un mélange comprenant un liant à l'état plastique et d'une charge magnétisable, la cavité comprenant une première face plane et une deuxième face, une étape de génération d'un flux magnétique dans la cavité pendant que ledit liant du mélange passe de l'état plastique à un état quasi-solide, le flux magnétique traversant la cavité selon des lignes de champs curvilignes s'étendant entre les première et deuxième faces, et une étape d'extraction d'un tronçon de corps réalisé. L'opération d'assemblage comprend une étape d'agencement en contact des premières faces des tronçons de corps, et une étape de solidarisation des premier et deuxième tronçons de corps pour ...

PROCESS OF FREEZE-DRYING Of HAEMOGLOBIN Of ANNELIDES

La présente invention se rapporte à un lyophilisat comprenant au moins une globine, un protomère de globine ou une hémoglobine extracellulaire d'Annélides, et un agent stabilisant choisi parmi les disaccharides, les polyols et les antioxydants. La présente invention se rapporte également à une composition comprenant : une solution comprenant au moins une globine, un protomère de globine ou une hémoglobine extracellulaire d'Annélides, et un agent stabilisant choisi parmi les disaccharides, les polyols et les antioxydants. La présente invention se rapporte enfin à un procédé de préparation du lyophilisat. The present invention relates to a lyophilizate comprising at least one globin, a globin protomer or an extracellular Annelides hemoglobin, and a stabilizing agent chosen from disaccharides, polyols and antioxidants. The present invention also relates to a composition comprising: a solution comprising at least one globin, a globin protomer or an extracellular Annelides hemoglobin, and a stabilizing agent selected from disaccharides, polyols and antioxidants. The present invention finally relates to a process for preparing the lyophilisate.

SEQUENCES, ANTIBODIES, PROCEEDED AND NECESSARY FOR THE DETECTION AND IN VITRO PROPORTIONING OF THE PERIOSTINE, FOR DIAGNOSIS OF THE FOLLOW-UP OR THE FORECAST OF PATHOLOGIES OR BIOLOGICAL PHENOMENA IMPLYING THE PERIOSTINE

A WOODWORKING MIXED FRAME AND METHOD OF MAKING SAME

USE OF A GLOBIN, A GLOBIN PROTOMER OR AN EXTRACELLULAR HEMOGLOBIN FOR THE PRESERVATION OF ORGANS, TISSUES, OR CELLS OF ORGANS OR TISSUES, OR CELL CULTURE

A WOODWORKING MIXED FRAME AND METHOD OF MAKING SAME

Procédé de fabrication d'un cadre mixte de menuiserie comprenant une étape d'assemblage d'au moins deux profilés disposés côte à côte pour former une poutre mixte, l'un (2) des profilés (2, 3) étant en un matériau non thermofusible et l'autre profilé (3) étant au moins partiellement en un matériau thermofusible. Ledit procédé comprend, après l'étape d'assemblage, une étape de découpe de la poutre en tronçons de poutre à extrémités biseautées à sensiblement 45°, une étape d'enlèvement de matière aux extrémités (21) de chaque profilé (2) en un matériau non thermofusible de sorte que l'extrémité (31) de chaque profilé (3) thermofusible s'étend en saillie de l'extrémité (21) de chaque profilé (2) non thermofusible au niveau de chaque extrémité de chaque tronçon de poutre et une étape d'assemblage par soudure suivant un assemblage à coupe d'onglet desdits tronçons de poutre formant à l'état assemblé un cadre, la soudure s'opérant au niveau des extrémités (31) des profilés (3) en matériau thermofusible desdits tronçons de poutre. A method of manufacturing a composite joinery frame comprising a step of assembling at least two sections arranged side by side to form a composite beam, one (2) of the profiles (2, 3) being made of a non-structural material thermofusible and the other section (3) being at least partially made of a hot-melt material. Said method comprises, after the assembly step, a step of cutting the beam into beam sections with bevelled ends at substantially 45 °, a material removal step at the ends (21) of each profile (2) in a non-heat-fusible material such that the end (31) of each hot-melt section (3) projects from the end (21) of each non-heat-fusible profile (2) at each end of each beam section and a welding assembly step in accordance with a miter-cutting assembly of said beam sections forming a frame in the assembled state, the welding occurring at the ends (31) of the profiles (3) of hot-melt ...

MAGNET MANUFACTURING METHOD MOLD.

MODULAR UNIT INTENDED TO CARRY COMPUTER MATERIALS ET/OUELECTRONIQUES

NOVEL HEAMOGLOBIN AND USES THEREOF

The present invention relates to isolated haemoglobin from worms belonging to the Nereididae family and its use in cell culture medium, in preservation solutions and as artificial oxygen carrier for transfusion. 1. Isolated haemoglobin or a portion thereof from annelid worms belonging to the family of Nereididae , having:a P50 from 5 to 15, preferably from 9 to 12 mm Hg at 6-7° C., from 12 to 20, preferably 15 to 18 mm Hg at 16-17° C. and from 20 to 50, preferably 30 to 44 mm Hg at 36-37° C.preferably no free cysteines,preferably no glycosylations.2Nereis virensNereis diversicola, Neanthes virensHediste diversicolor.. Haemoglobin or a portion thereof according to claim 1 , from or or3. Haemoglobin according to claim 1 , which is extracellular and has a molecular weight from 3 to 4 million Daltons.4. Portion of haemoglobin according to claim 1 , which has a molecular weight comprised from 14 000 to 30 000 Daltons claim 1 , preferably from 14 000 to 60 000 Daltons claim 1 , preferably from 14 000 to 250 000 Daltons claim 1 , preferably 14 000 to 500 000 Daltons claim 1 , preferably from 500 000 to 4 000 000 Daltons.5. Haemoglobin or a portion thereof according to claim 1 , wherein it comprises:one or two monomers of 10 to 20 kDa each, more preferably of 15 to 16 kDa each,one trimer of 40 to 55 KDa, preferably 48 to 50 kDa, anda dimeric linker composed of two monomeric chains around 20 to 30 kDa each, preferably between 22 to 26 kDa each.6. A composition comprising an haemoglobin or a portion thereof according to claim 1 , said composition being in the form of an aqueous solution claim 1 , a thawed solution or a lyophilised powder.7. A pouch comprising the composition according to .8. A cell culture medium comprising the composition according to .9. A cell culture medium according to claim 8 , wherein said cell culture medium is a medium formulated to promote recombinant protein production.10. A cell culture medium according to claim 8 , wherein said cell culture ...

SEQUENCES, ANTIBODIES, METHODS AND KITS FOR DETECTION AND IN VITRO ASSAY OF PERIOSTIN, IN ORDER TO PROVIDE A DIAGNOSIS, FOLLOW-UP OR PROGNOSIS OF DISEASES AND BIOLOGICAL PHENOMENA INVOLVING PERIOSTIN

Detection sequences of periostin having from 6 to 30 amino acids and which include all or part of peptide sequence SEQ ID No. 1, SEQ ID No. 2 or SEQ ID No. 3, or a homologous peptide sequence. Antibodies suitable for specifically recognizing minimally one of these detection sequences, including an anti-periostin antibody, are disclosed. Periostin detection and dosage processes and kits that use these antibodies are also disclosed. A periostin marker for early diagnosis, tracking and prognosis of pathologies that involve periostin, including benign osteolysis such as inflammatory diseases, including osteoarticular diseases, and malignant osteolysis, such as cancers with bone metastases, is provided. 114-. (canceled)15. Peptide sequence for periostin detection which is made up of 6 to 30 amino acids and which includes all or part of peptide sequence SEQ ID No. 1 , SEQ ID No. 2 or SEQ ID No. 3 , or a peptide sequence with a degree of homology greater than or equal to 80% , preferably greater than or equal to 85% vis-à-vis of at least one of the sequences selected from the group consisting of SEQ ID No. 1 , SEQ ID No. 2 and SEQ ID No. 3.16. Nucleic sequence coding the peptide sequence of .17. Means for periostin detection comprising a recognition tool specific to one or more peptide sequences of claim 15 , wherein said tool includes an anti-periostin antibody claim 15 , and/or one of its functional fragments claim 15 , specific to SEQ ID No. 1 claim 15 , SEQ ID No. 2 claim 15 , SEQ ID No. 3 claim 15 , or a peptide sequence with a degree of homology greater than or equal to 80% claim 15 , preferably greater than or equal to 85% vis-à-vis at least one of the sequences selected from the group consisting of SEQ ID No. 1 claim 15 , SEQ ID No. 2 and SEQ ID No. 3.18. A method for producing a means for periostin detection claim 15 , in particular an anti-periostin antibody claim 15 , which method consists essentially of:{'claim-ref': {'@idref': 'CLM-00015', 'claim 15'}, 'a) ...

Affinity Relationship Based Ecommerce

Data characterizing an offer for sale of a good or service by a seller is received. The data specifies constraints of the offer. The constraints identify a plurality of groups of potential buyers to which the offer is to be conveyed and characterizes conditions specifying how the offer is to be conveyed to each group. At least one of the groups is determined based on an affinity relationship of the potential buyers in that group to the seller. The terms of the offer may vary between at least two of the plurality of groups based on the relationship. A plurality of formatted offers can be generated. Each formatted offer corresponds to a respective group and to an online marketplace. At least one of the formatted offers can be posted to a respective group according to the conditions. Related apparatus, systems, techniques and articles are also described.

ORGAN-PRESERVING COMPOSITION AND USES

The invention relates to the use of a composition comprising at least one globin, one globin protomer or one extracellular hemoglobin of Annelida, a stabilizing solution and/or a solution for conserving organs, said composition having a temperature of between 0° C. and 37° C., for preserving an organ in a donation after brain death donor or a donation after cardiac death donor. 1. The use of a composition comprising at least one globin , one globin protomer or one extracellular hemoglobin of annelids , a stabilizing solution and/or an organ preservation solution , said composition having a temperature of between 0° C. and 37° C. , for preserving an organ in a donation after brain death donor or a donation after cardiac death donor.2. The use as claimed in claim 1 , wherein the extracellular hemoglobin of annelids is chosen from the extracellular hemoglobins of polychaete annelids.3. The use as claimed in wherein the stabilizing solution is an aqueous solution comprising salts claim 1 , and confers on the composition according to the invention a pH of between 6.5 and 7.6.4. The use as claimed in claim 1 , wherein the stabilizing solution is an aqueous solution comprising 90 mM of NaCl claim 1 , 23 mM of Na gluconate claim 1 , 2.5 mM of CaCl claim 1 , 27 mM of Na acetate claim 1 , 1.5 mM of MgCl claim 1 , 5 mM of KCl claim 1 , and a pH of 7.1±0.5.5. The use as claimed in claim 1 , wherein the organ preservation solution is an aqueous solution having a pH of between 6.5 and 7.5 and comprising salts claim 1 , sugars; antioxidants; active agents; and optionally.6. The use as claimed in claim 1 , wherein the extracellular hemoglobin of annelids claim 1 , globin protomers thereof and/or globins thereof is present at a concentration claim 1 , relative to the final volume of composition claim 1 , of between 0.001 mg/ml and 100 mg/ml claim 1 , and in that the composition has an osmolarity of between 250 and 350 mOsm/l.7. The use of an aqueous solution comprising sodium ...

ALKALI METAL OXYANION ELECTRODE MATERIAL HAVING A CARBON DEPOSITED BY PYROLYSIS AND PROCESS FOR MAKING SAME

An alkali metal oxyanion cathode material comprising particles, where the particles carry, on at least a portion of the particle surface, carbon deposit by pyrolysis is described. The particles have the general formula A: M:M′:X04 where the average valency of M is −2 or greater; A is at least one alkali metal selected from Li, Na and K; M is at least Fe and/or Mn; and M′ is a metal of valency of 2+ or more. 16-. (canceled)8. The process according to claim 7 , wherein M′ comprises Zr.9. The process according to claim 7 , wherein the gaseous or vaporous atmosphere is humidified.10. The process according to claim 7 , wherein the thermal step is performed in a chemical reactor that comprises a zone fed by an external flow of gas and/or vaporous atmosphere comprising a carbonaceous chemical and/or an organic chemical comprising carbon.11. A process according to claim 7 , wherein the carbonaceous chemical comprises a decomposition product of an organic compound comprising carbon.12. The process according to claim 7 , wherein the carbonaceous chemical is a compound having at least 40 wt. % of carbon.13. The process according to claim 12 , wherein the carbonaceous compound is methanol claim 12 , isopropanol and/or butanol.14. The process according to claim 7 , wherein the precursors comprise:a) at least one source compound of an alkali metal;b) at least one source compound of a metal M selected from Fe and/or Mn;c) at least one source compound of a metal M′, where M′ in the final product is a 2+ or more metal;d) at least one source compound of P, if the element P is not present in another source compound;e) at least one source compound of Si, if the element Si is not present in another source compound; andf) at least one source compound of carbon.15. The process according to claim 14 , wherein the source compound b) is partially replaced by at most 15% of one or more other metals selected from Ni and Co claim 14 , and/or by one or more aliovalent or isovalent metals ...

QUERY-BASED IDENTIFIERS FOR CROSS-SESSION RESPONSE TRACKING

Systems and methods for cross-session response tracking in a distributed computing environment using query identifiers generated based on search parameters. A search query including search parameters is received from a client device. A query identifier for the search query is generated based on the search parameters. One version of a search result among multiple versions of the search result is selected based on the query identifier and sent to the client device. A record in a transaction database is correlated with the selected version of the search result using the query identifier. 1. A system comprising:a computing device; anda computer-readable storage medium comprising a first set of instructions that upon execution by the computing device cause the system to:receive, at a reservation system, a search query corresponding to a travel request for a customer from a client device, the search query including a plurality of search parameters determined locally at the client device using input data received via an interface on the client device;generate, by the reservation system, a query identifier for the search query based on the plurality of search parameters;select one version of a search result among a plurality of versions of the search result based on the query identifier, each version of the search result among the plurality of versions of the search result being distinct from the other versions of the search result by virtue of a variant, the search result including a travel itinerary that satisfies the plurality of search parameters; andsend the selected version of the search result to the client device, the selected version of the search result updating the interface on the client device.2. The system of claim 1 , wherein the computer-readable storage medium further comprises a second set of instructions that upon execution by the computing device further cause the system to:correlate a record in a reservation database with the selected version of the ...

METHOD, DEVICE AND COMPUTER PROGRAM PRODUCT FOR THE GEOPOSITIONING OF A RADIO TRANSMITTER

The invention relates to a method for geolocating a signal-transmitting device, the geolocation method comprising: 12. A method for geolocating a signal-transmitting device , said signal-transmitting device transmitting a radio signal () , the geolocation method comprising:{'b': 3', '2', '3, 'sub': 'i', 'a. supplying positions of a plurality of reception stations (, GWi) of a radio communication network and dates of reception (T) of the radio signal () by said reception stations (, GWi),'}{'b': 3', '3, 'b. selecting a reference station (, GWi) from among the plurality of reception stations (, GWi),'}{'b': 14', '13', '3, 'c. defining () a scanning zone () as a function of the positions (Xi, Yi) of said reception stations (, GWi),'}{'b': 13', '17, 'd. subdividing the scanning zone () into a plurality of subzones () as a function of a scanning granularity,'}{'b': 17', '25', '28', '17', '25', '28', '17', '25', '28, 'claim-text': [{'b': 19', '17', '25', '28, 'determining () a tested position (k,l) included in said subzone (, , ),'}, {'b': 3', '2', '3', '2', '2', '3, 'img': [{'@id': 'CUSTOM-CHARACTER-00001', '@he': '7.53mm', '@wi': '135.93mm', '@file': 'US20200124693A1-20200423-P00999.TIF', '@alt': 'text missing or illegible when filed', '@img-content': 'character', '@img-format': 'tif'}, {'@id': 'CUSTOM-CHARACTER-00002', '@he': '7.53mm', '@wi': '135.93mm', '@file': 'US20200124693A1-20200423-P00999.TIF', '@alt': 'text missing or illegible when filed', '@img-content': 'character', '@img-format': 'tif'}, {'@id': 'CUSTOM-CHARACTER-00003', '@he': '7.53mm', '@wi': '135.93mm', '@file': 'US20200124693A1-20200423-P00999.TIF', '@alt': 'text missing or illegible when filed', '@img-content': 'character', '@img-format': 'tif'}], 'sub': i', '0, 'calculating, for each reception station (, GWi) a respective transmission error parameter () as a function of a date of reception (T) of the radio signal () by said reception station (, GWi), of a date of reception of the radio signal () by ...

Use of a Haemoglobin for the Preparation of Dressings and Resulting Dressings

The invention relates to the use of a haemoglobin for the preparation of dressings and to the resulting dressings. 140.-. (canceled)41. A method for the external treatment of open , deep or chronic wounds , or of periodontal diseases , or of a gastric wounds or of tissues , the method comprising administering a dressing comprising a hemoglobin from a vertebrate or invertebrate animal immobilized in a matrix , wherein the matrix is based on polymerized hydrocolloids and wherein the hemoglobin is stable in the matrix , said matrix being physiologically acceptable , and having a water content of from 0 to 98% , and said matrix being formed from a three-dimensional network defining pores , the size of which is from 2 nm to 300 μm.42. The method of claim 41 , wherein the amount of hemoglobin claim 41 , relative to the total dry weight of hemoglobin and of matrix claim 41 , is from 0.1% (w/w) to 60% (w/w).43. The method of claim 41 , wherein the percentage water content is from greater than 50%.44. The method of claim 41 , wherein the hemoglobin is chemically modified or crosslinked human or vertebrate-animal hemoglobin.45. The method of claim 41 , wherein the hemoglobin is an extracellular hemoglobin from an invertebrate animal chosen from the phylum Annelida.46. The method of claim 41 , wherein said matrix is based on chitosan claim 41 , carrageenans claim 41 , carboxymethylcellulose or alginates.47. The method of claim 46 , wherein said matrix is based on calcium alginate claim 46 , and wherein the amount of hemoglobin present in the matrix claim 46 , relative to the total weight of hemoglobin and of the matrix is 55% (w/w) to 85%.48. A dressing comprising extracellular Annelid hemoglobin immobilized and stable in a hydrocolloid network claim 46 , and having a water content of from 0% to 98% claim 46 , said network defining pores claim 46 , the size of said pores being from 2 nm to 1 μm claim 46 , wherein the Annelid hemoglobin is from about 0.1 to about 60% by weight ...

HISTORY-BASED PROBABILITY FORECASTING

An apparatus, program product and method collect and maintain booking histories for customers within one or more computerized databases to incorporate the past behaviors of customers booked for service components when forecasting show probabilities for those service components. A show rate forecast operation, for example, may be used to determine a show probability for a service component based upon both a personal show probability for one or more customers booked on the service component and anonymous statistical show probability data relevant to the service component. 1. A method of forecasting show probability for a service component , the method comprising:maintaining, in a computerized database, data representing a booking history for a first customer booked for the service component;accessing, with at least one processor, the data representing the booking history in the database;determining, with at least one processor, a personal show probability for the first customer based upon the accessed data representing the booking history;accessing, with at least one processor, anonymous statistical show probability data relevant to the service component; anddetermining, with at least one processor, a show probability for the service component based on the determined personal show probability for the first customer and the accessed anonymous statistical show probability data.2. The method of claim 1 , wherein the service component is for travel on a travel vehicle between an origin location and a destination location.3. The method of claim 1 , wherein the service component comprises a flight between an origin airport and a destination airport.4. The method of claim 1 , wherein determining the personal show probability for the first customer based upon the accessed data representing the booking history includes:identifying at least one non-redeemed booking for the first customer; anddetermining the personal show probability for the first customer based at least in part ...

ANNELID HAEMOGLOBIN LYOPHILISATION PROCESS

The present invention relates to a lyophilizate comprising at least one globin, one globin protomer or one extracellular hemoglobin of annelids, and a stabilizer chosen from disaccharides, polyols and antioxidants. The present invention also relates to a composition comprising: a solution comprising at least one globin, one globin protomer or one extracellular hemoglobin of annelids, and a stabilizer chosen from disaccharides, polyols and antioxidants. 1. A lyophilizate comprising at least one extracellular hemoglobin , globin protomer or globin of annelids , and a stabilizer chosen from disaccharides , polyols and antioxidants.2. A composition comprising:a solution comprising at least one extracellular hemoglobin, globin protomer or globin of annelids, anda stabilizing chosen from trehalose and ascorbic acid.3. The lyophilizate of claim 1 , wherein the extracellular hemoglobin of annelids is an extracellular hemoglobin of polychaete annelids.4. The lyophilizate of claim 1 , wherein the stabilizer is chosen from trehalose claim 1 , sucrose claim 1 , mannitol claim 1 , sorbitol and ascorbic acid claim 1 , preferably from trehalose and ascorbic acid.5. A process for preparing the lyophilizate of claim 1 , comprising:i) the mixing of a solution comprising at least one extracellular hemoglobin, globin protomer or globin of annelids with a stabilizer chosen from disaccharides, polyols and antioxidants;ii) the freezing of the mixture at a temperature of between −10° C. and −100° C. for a time of at least 24 h;iii) the sublimation of the frozen mixture for at least 2 h, under vacuum;iv) the final drying of the mixture until a powder is obtained.6. The process of claim 5 , wherein the stabilizer comprises disaccharides or polyols in a concentration of between 1 and 500 mg/ml.7. The process of claim 5 , wherein the stabilizer comprises antioxidants in a concentration of between 3 and 20 mM.8. The process of claim 5 , wherein the stabilizer comprises trehalose or sucrose ...

ALKALI METAL OXYANION ELECTRODE MATERIAL HAVING A CARBON DEPOSITED BY PYROLYSIS AND PROCESS FOR MAKING SAME

An alkali metal oxyanion cathode material comprising particles, where the particles carry, on at least a portion of the particle surface, carbon deposit by pyrolysis is described. The particles have the general formula A:M:M′:XO4 where the average valency of M is +2 or greater; A is at least one alkali metal selected from Li, Na and K; M is at least Fe and/or Mn; and M′ is a metal of valency of 2+ or more. 1. An alkali metal oxyanion cathode material comprising particles , where the particles carry , on at least a portion of the particle surface , carbon deposited by pyrolysis wherein the particles have the general formula A:M:M′:XO , whereinA is at least one alkali metal selected from Li, Na and K;M is at least Fe and/or Mn, wherein the average valence of M is +2 or greater, and wherein M can be substituted by at most 15% at. of one or more metal at oxidation levels between +1 and +5;M′ is a metal of valence of 2+ or more;{'sub': 4', '4', '4', '4, 'XOis POand/or SiO, and can be partly substituted by another XO, in which X is either P, S, V, Si, Nb, Mo or any combinations thereof,'}{'sub': '4', 'wherein the elements in the general formula A:M:M′:XOare present in the following general ratios 1:0.95-0.98:0.02 to <0.05:1.'}2. The cathode material according to claim 1 , wherein the particles have the general formula A:M:M′:PO:SiO claim 1 , wherein the elements in the general formula are present in the following general ratios 1:0.95-0.98:0.02 to <0.05:p:s claim 1 , wherein the ratio “s” is equal to the ratio of M′ and wherein the ratio “p” is equal to (1−“s”).3. The cathode material according to or claim 1 , wherein M′ comprises Zr.4. A process for making an alkali metal oxyanion cathode material comprising particles claim 1 , where the particles carry claim 1 , on at least a portion of the particle surface claim 1 , a carbon coating deposited by pyrolysis claim 1 , said process comprisingperforming a thermal step of high-energy milled precursors of the cathode material ...

COMBINATION OF AN ANTI-CANCER AGENT SUCH AS A TYROSINEKINASE INHIBITOR AND A STAT5 ANTAGONIST, PREFERABLY A THIAZOLIDINEDIONE, FOR ELIMINATING HEMATOLOGIC CANCER STEM CELLS IN VIVO AND FOR PREVENTING HEMATOLOGIC CANCER RELAPSE

Provided are methods for eliminating hematologic cancer stem cells in vivo, and thus preventing cancer relapse. The methods comprise a Signal Transducer and Activator of Transcription 5 (STAT5) antagonist (e.g., a PPARy agonist) after the patient has had ana initial course of treatment with an anti-cancer agent (e.g., a TKI), to eliminate residual cancer stem cells which cause re lapse. 1. A method of eliminating hematologic cancer stem cells in vivo comprising:(A) administering to a patient with hematologic cancer, an effective amount of an anti-cancer agent; and(B) administering to the patient an effective amount of a Signal Transducer and Activator of Transcription 5 (STAT5) antagonist.2. A method of preventing hematologic cancer relapse in a patient comprising:(A) administering to the patient an effective amount of an anti-cancer agent; and(B) administering to the patient an effective amount of a STAT5 antagonist.3. The method according to any of the preceding claims , wherein the anti-cancer agent is administered prior to the STAT5 antagonist , until a stable cumulative incidence of response in the patient is achieved.4. The method according to claim 3 , wherein the response is selected from the group consisting of complete hematological remission (CHR) claim 3 , major cytological remission (MCR) claim 3 , complete cytological remission (CCR) claim 3 , major molecular remission (MMR) and complete molecular remission (CMR).5. The method according to any of the preceding claims claim 3 , wherein the anti-cancer agent is administered for at least 3 months prior to administration of the STAT5 antagonist.6. The method according to claim 5 , wherein the STAT5 antagonist is administered for 2-12 months concurrently with the anti-cancer agent.7. The method according to claim 6 , wherein administration of the anti-cancer agent is continued after administration of the STAT5 antagonist is discontinued.8. The method according to any of the preceding claims claim 6 , ...

ELECTROCHROME CELL.

BALL CAGE FOR SCREW / NUT TYPE DRIVE ASSEMBLY

LINEAR ACTUATOR WITH VIS-NUT SYSTEM

LA PRESENTE INVENTION CONCERNE UN ACTIONNEUR LINEAIRE DESTINE A ACTIONNER NOTAMMENT UN VANTAIL DE PORTAIL. IL COMPORTE UN MOTEUR 1 DONT L'ARBRE DE SORTIE 2 EST LIE A UNE VIS 4, PAR EXEMPLE A DROITE, AVEC LAQUELLE EST EN PRISE UN ECROU 5 DONT EST SOLIDAIRE UN BRAS 10 PARALLELE A LA VIS, RELIE, PAR UN LIMITEUR DE COUPLE A FRICTION 13, A UN ELEMENT INTERMEDIAIRE 14, FIXE EN ROTATION, DESTINE A ETRE RELIE A UN ELEMENT A ACTIONNER 16, TEL QU'UN VANTAIL. L'ECROU 5 COMPORTE UNE PREMIERE PARTIE PROFILEE 21 TOURNEE VERS L'EXTERIEUR, PREVUE POUR COOPERER, LORSQUE CET ECROU OCCUPE UNE SEULE POSITION EXTREME, AVEC UNE SECONDE PARTIE PROFILEE 22, EN FORME DE BAIONNETTE, RACCORDEE A LA FACE 8A D'UN ELEMENT FIXE, CETTE SECONDE PARTIE 22 ENTOURANT AU MOINS LOCALEMENT LA VIS 4 ET L'ECROU 5. CETTE BAIONNETTE 22 EST ORIENTEE DE FACON A EMPECHER L'ECROU 5, LORSQU'IL ATTEINT CETTE POSITION AXIALE EXTREME, DE TOURNER DANS LE MEME SENS QUE L'ARBRE-MOTEUR 2 ET QUE LA VIS 4. THE PRESENT INVENTION CONCERNS A LINEAR ACTUATOR INTENDED TO ACTUATE IN PARTICULAR A GATE LEAF. IT INCLUDES A MOTOR 1 OF WHICH THE OUTPUT SHAFT 2 IS LINKED TO A SCREW 4, FOR EXAMPLE ON THE RIGHT, WITH WHICH IS IN TAKEN A NUT 5 WHICH IS SOLIDARITY AN ARM 10 PARALLEL TO THE SCREW, CONNECTED BY A TORQUE LIMITER AT FRICTION 13, TO AN INTERMEDIATE ELEMENT 14, FIXED IN ROTATION, INTENDED TO BE CONNECTED TO AN ELEMENT TO BE ACTUATED 16, SUCH AS A LEAF. NUT 5 INCLUDES A FIRST PROFILED PART 21 TURNED OUT TO THE EXTERIOR, INTENDED TO COOPERATE, WHEN THIS NUT OCCUPIES A SINGLE EXTREME POSITION, WITH A SECOND PROFILED PART 22, IN THE FORM OF A BAIONET, CONNECTED TO THE FACE 8A OF AN ELEMENT FIXED, THIS SECOND PART 22 SURROUNDING AT LEAST LOCALLY THE SCREW 4 AND THE NUT 5. THIS BAYONET 22 IS ORIENTED SO AS TO PREVENT THE NUT 5, WHEN IT REACHES THIS EXTREME AXIAL POSITION, FROM TURNING IN THE SAME DIRECTION AS L '' MOTOR SHAFT 2 AND SCREW 4.

transmission device and self-propelled machine equipped with such a transmission device

Dispositif (1) de transmission comprenant un boîtier (2) de transmission, un arbre (3) de sortie du boîtier s’étendant au moins partiellement en saillie du boîtier (2), un moteur (4) électrique équipé d’un arbre (5) moteur rotatif, une transmission (6) de mouvement de l’arbre (5) moteur à l’arbre (3) de sortie logée au moins partiellement à l’intérieur du boîtier (2) et accessible à l’arbre (5) moteur depuis l’extérieur du boîtier (2) via une ouverture (7) ménagée dans ledit boîtier (2), ledit moteur (4), extérieur au boîtier (2), présentant une surface (8) dite d’appui positionnable en appui contre le boîtier (2) à l’état en prise de l’arbre (5) moteur avec la transmission (6) de mouvement, ce moteur (4) étant protégeable par un capot (9) couplable au boîtier (2). Le dispositif (1) de transmission comprend un organe (10) élastiquement déformable de maintien de la surface (8) d’appui du moteur (4) en position d’appui contre le boîtier (2), cet organe (10) élastiquement déformable étant, à l’état couplé du capot (9) au boîtier (2), logé dans le capot (9). Figure pour l’abrégé : Fig. 3 Transmission device (1) comprising a transmission housing (2), an output shaft (3) of the housing extending at least partially projecting from the housing (2), an electric motor (4) equipped with a shaft ( 5) rotary motor, a transmission (6) of movement from the motor shaft (5) to the output shaft (3) housed at least partially inside the housing (2) and accessible to the shaft (5) ) motor from outside the casing (2) via an opening (7) made in said casing (2), said motor (4), outside the casing (2), having a so-called bearing surface (8) which can be positioned in bearing against the housing (2) in the engaged state of the motor shaft (5) with the movement transmission (6), this motor (4) being able to be protected by a cover (9) which can be coupled to the housing (2). The transmission device (1) comprises an elastically deformable member (10) for maintaining the bearing surface (8) of ...

Electrochromic cell.

La présente invention concerne une cellule électrochrome comprenant un substrat (1) portant une électrode (2), une couche électrochrome persistante (3), une couche d'électrolyte (6), et une contre-électrode (5) sur un second substrat (4), au moins une telle électrode et un substrat étant transparents. La couche d'électrolyte comprend une matière donneuse de cations lithium qui, sous l'influence d'un potentiel appliqué entre les dites électrodes, donne des cations lithium pour leur insertion réversible dans la couche électrochrome en changeant la couleur de la matière électrochrome, et un additif qui est sélectionné pour effectuer l'inversion d'un tel changement de couleur par réaction chimique en l'absence d'un tel potentiel. Cette cellule électrochrome peut être utilisée pour former des toits ouvrants vitrés ou des rétroviseurs. The present invention relates to an electrochromic cell comprising a substrate (1) carrying an electrode (2), a persistent electrochromic layer (3), an electrolyte layer (6), and a counter electrode (5) on a second substrate ( 4), at least one such electrode and one substrate being transparent. The electrolyte layer comprises a lithium cation donor material which, under the influence of a potential applied between said electrodes, gives lithium cations for their reversible insertion into the electrochromic layer by changing the color of the electrochromic material, and an additive which is selected to effect the reversal of such a color change by chemical reaction in the absence of such a potential. This electrochromic cell can be used to form sunroofs or mirrors.

MOTORIZED HANDLING ROLLER

Packaging for elongated hooks arranged in parallel rows, in particular hooks for holding slates on roofs.

Motorised handling roller

Motorised handling roller for producing a transport path. It includes an electric motor whose rotor is connected kinematically to a tubular cylinder 1 via a speed reducer (reducing gear). Between the speed reducer (reducing gear) 4 and the tubular cylinder 1 is arranged a friction coupling 17, 18, 19 which can be adjusted from the outside of the roller through an axial passage 21 of the shaft 2. The speed reducer (reducing gear) as well as the motor are thus protected against excessive braking forces or acceleration forces caused by the load transported.

Spout with removable micro-valve, non-return for synchronized spraying

SEQUENCES, ANTIBODIES, METHODS AND NECESSARY FOR DETECTION AND IN VITRO ASSAYING OF PERIOSTIN FOR THE DIAGNOSIS OF MONITORING OR PROGNOSIS OF PATHOLOGIES OR BIOLOGICAL PHENOMENA INVOLVING PERIOSTIN

L'invention concerne de nouvelles séquences de détection SP de la périostine. Ces séquences ont de 6 à 30 acides aminés et incluent tout ou partie de la séquence peptidique SEQ ID N°1, SEQ ID N°2 ou SEQ ID N°3 ou d'une séquence peptidique homologue à celles-ci. L'invention concerne également des anticorps aptes à reconnaître spécifiquement au moins l'une de ces séquences de détection, de préférence un anticorps anti-périostine. L'invention concerne également des procédés et des nécessaires de détection et de dosage de la périostine qui utilisent ces anticorps. Ce faisant, l'invention offre un marqueur périostine de diagnostic précoce, de suivi et de pronostic de pathologies qui impliquent la périostine, car elles s'accompagnent d'ostéolyse bénigne (affections inflammatoires: maladies ostéo-articulaires) ou maligne (cancers avec métastases osseuses). The invention relates to novel SP detection sequences of periostin. These sequences have from 6 to 30 amino acids and include all or part of the peptide sequence SEQ ID No. 1, SEQ ID No. 2 or SEQ ID No. 3 or a peptide sequence homologous thereto. The invention also relates to antibodies capable of specifically recognizing at least one of these detection sequences, preferably an anti-periostin antibody. The invention also relates to methods and kits for detecting and assaying periostin using these antibodies. In doing so, the invention provides a periostin marker for early diagnosis, monitoring and prognosis of pathologies that involve periostin, as they are accompanied by benign osteolysis (inflammatory diseases: osteoarticular diseases) or malignant (cancers with metastases bone).

METHOD FOR DETERMINING A SCREEN REPRESENTATIVE OF OXIDATIVE STRESS OF A PATIENT ON A SCALE OF 0 TO 10

Paint applying sleeve locking/unlocking device for paint roller, has blade and hook presenting retaining neck positioned in groove whose walls are defined by annular shoulder and outer side of flange

The device has a hook (520) provided on a frame (100), and presenting an outer retaining neck positioned in a groove whose walls are defined by an annular shoulder (441) and an outer side of a flange (400). The hook and a blade are presented under the form of a pallet articulated by a hinge fixed on one of the outer sides of a branch of a sliding block. A sleeve (200) is closed by two hermetic barriers in the presence of two flanges. An independent claim is also included for a paint roller comprising a paint applying sleeve.

Device for locking a two-leaf gate in a closed position

The present invention relates to automatic devices intended for locking the two leaves of a gate or of a door in a closed position. Such a device comprises, according to the invention, a first stop 11 fixed to the first leaf 1 and intended for coming to bear against the first front face 31 of a stationary shoe 3 anchored in the ground. It comprises, furthermore, a second stop 12 pivoted in its upper part about a horizontal axle 6 supported by the first leaf and, above this axle, an extension 13 directed upwards and projecting completely beyond the first leaf 1 laterally. This extension 13 constantly tends, under the action of a return means 14, to tilt in the direction of the second leaf 2 by an angular amount limited by a stop 18. When the second leaf 2 is closed after the first 1, the extension 13 is laid against the second leaf 2, and the second stop 12 is located opposite a second front face 32, opposite the first 31, of the stationary shoe 3 which is thus locked between the stops 11 and 12 when the lock, not shown in the drawing, connecting the two leaves 1 and 2 is closed.

Improvements to gas and oil cookers

Package for the locking and centring of products of the spool type with a variable diameter

The present invention relates to a package for the locking and centring of products of the spool (1) type with a variable diameter, comprising a case (3) with four side faces (4, 5, 6, 7), a top and a bottom, the said package being characterised in that it also comprises at least one support panel (13, 16), normally rectangular, whose lateral dimensions allow it to be held firmly with respect to the four side faces (4, 5, 6, 7) of the said case (3) when the said support panel (13, 16) is inserted in it, this same support panel (13, 16) supporting, facing the inside of the said case (13), at least one centring hub for the core (2) of at least one product of the spool (1) type to be packaged. The package according to the invention may be used, in particular, for transporting spools of special paper for visiting card printing machines or similar.

Differential device and self-propelled machine equipped with such a device

Dispositif (1) différentiel interposable entre des arbres de roues coaxiaux et le moteur d’un engin roulant, et comprenant un pignon (2), deux mécanismes d’embrayage, une enveloppe (6) logeant les mécanismes d’embrayages et définissant un passage (7) traversant de réception des arbres de roues, chaque mécanisme d’embrayage comprenant un premier élément (4) d’embrayage et un deuxième élément (5) d’embrayage rotatifs montés mobiles à rotation autour d’un axe confondu avec l’axe longitudinal du passage (7) traversant. L’enveloppe (6) affecte la forme d’un boîtier (8) comprenant un corps (9) et un couvercle (10) munis chacun d’une ouverture (91, 101) traversante, le pignon (2) est porté par le corps (9) qui comprend un fond (92) muni de l’ouverture (91) traversante dudit corps (9) et une paroi (93) latérale périphérique, le pignon (2), ou la couronne dentée, réalisé d’une seule pièce avec ledit corps (9) s’étendant au moins partiellement autour de la paroi (93) latérale périphérique dudit corps (9). Figure pour l’abrégé : Fig. 2 Differential device (1) interposable between coaxial wheel shafts and the engine of a rolling machine, and comprising a pinion (2), two clutch mechanisms, an envelope (6) housing the clutch mechanisms and defining a (7) through-receiver of the wheel shafts, each clutch mechanism comprising a first rotary clutch element (4) and a second rotary clutch element (5) mounted to rotate about an axis coinciding with the longitudinal axis of the passage (7) crossing. The envelope (6) takes the form of a box (8) comprising a body (9) and a lid (10) each provided with a through opening (91, 101), the pinion (2) is carried by the body (9) which comprises a bottom (92) provided with the through opening (91) of said body (9) and a peripheral side wall (93), the pinion (2), or the ring gear, made in a single piece with said body (9) extending at least partially around the peripheral side wall (93) of said body (9). Figure for abstract: Fig. 2

DEVICE FOR LOCKING IN A CLOSED POSITION OF A TWO-LEAF GATE

Determining patient's oxidative stress score, comprises initial calibration comprising obtaining a data base, statistical analysis of the database, evaluation of markers, assigning weight for each value and calculating the stress score

Determination of patient's oxidative stress score, in a 0-10 scale, comprises initial calibration comprising selection of a series of stress related biological markers from blood of a panel of people being healthy or presenting pathologies and known disorders and evaluating the markers by proportioning, to obtain a data base, statistical analysis of the database, evaluation of the markers of the patient belonging to several marker groups, assigning a weight on the gravity scale for each value and calculating a patient's oxidative stress score using a formula given in the specification. Determination of patient's oxidative stress score, in a 0-10 scale, comprises initial calibration comprising selecting a series of biological markers related to the oxidative stress from blood of a panel of people being healthy or presenting pathologies and known clinical disorders and evaluating the markers by proportioning, to obtain a data base, carrying out a statistical analysis of the database, evaluating biological markers of the patient belonging to several biological marker groups, assigning a weight on the gravity scale to each of the obtained values and calculating a patient's oxidative stress score i.e. specific to the patient using a formula given in the specification. The statistical analysis of the database comprises establishing a gravity scale, associated with the variations from reference values, for each marker, assembling the markers in at least three groups expressing different information associated to different stages of oxidative stress development and corresponding respectively to exogenous/endogenous antioxidants and with oxidative damage markers and assigning a weight to each group of markers and assigning a weight to each marker within each group.

ELECTROMECHANICAL OPERATION DEVICE FOR SLIDING MOVEMENT DOOR

METHOD FOR GEOLOCATING A RADIO TRANSMITTER

L'invention concerne un procédé de géolocalisation d'un dispositif émetteur de signal, le procédé de géolocalisation comportant : a. Fournir des positions d'une pluralité de stations et des dates de réception du signal radio par lesdites stations, b. Sélectionner une station de référence, c. Définir une zone de balayage, d. Subdiviser la zone de balayage en fonction d'une granularité de balayage, e. Pour chaque sous-zone, calculer un degré d'erreur cumulée de ladite sous-zone, f. sélectionner une sous-zone présentant un degré d'erreur cumulé minimal, g. définir une nouvelle zone de balayage, h. définir une nouvelle granularité de balayage, i. itérer le procédé à partir de l'étape d). The invention relates to a method for geolocation of a signal transmitter device, the geolocation method comprising: a. Provide positions of a plurality of stations and dates of reception of the radio signal by said stations, b. Select a reference station, c. Define a scanning area, d. Subdivide the scan area based on a scan granularity, e. For each sub-area, calculate a cumulative error degree of said sub-area, f. selecting a subfield having a minimum cumulative degree of error, g. define a new scanning area, h. define a new scan granularity, i. iterating the process from step d).

Actuating arrangement of an up- and over or sectional door

Equipment for placing a pin bushing, and kit including same

Pour la mise en place de douille (300) à clavette (320), l'outillage peut être monté sur un outil de vissage (100), et raccordé à une alimentation pneumatique. Il comporte un dispositif de transmission de couple de vissage (14, 52), pour visser la douille, et dans un carter (12), un dispositif de percussion de clavette (16), permettant de sertir la clavette sur la douille lorsqu'une pression de sertissage lui est appliquée par l'alimentation pneumatique. Le dispositif de percussion (16) comporte une pluralité de plateaux (18A, 18B, 18C) sensiblement perpendiculaires à l'axe de vissage. La pression de sertissage brutalement appliquée sur les plateaux à l'intérieur du carter (12), entraine le dispositif de percussion de clavette et permet le sertissage de celles-ci. L'outillage ne comprend pas de pièces mécaniques en mouvement et présente une grande fiabilité. L'invention vise également un kit comprenant un outillage de ce type et un outil de vissage. For the establishment of bushing (300) with a key (320), the tooling can be mounted on a screwdriver (100), and connected to a pneumatic supply. It comprises a torque transmission device screwing device (14, 52), for screwing the sleeve, and a housing (12), a key percussion device (16), allowing crimp the key on the socket when a pressure of crimping is applied to it by the pneumatic supply. The device percussion (16) has a plurality of trays (18A, 18B, 18C) substantially perpendicular to the screw axis. Pressure crimping brutally applied to the trays inside the housing (12), drives the key percussion device and allows the crimping thereof. Tooling does not includes no moving mechanical parts and presents a large reliability. The invention also relates to a kit comprising tooling of this type and a screwing tool.

METHOD AND TOOLING FOR THE INSTALLATION OF FIXING ELEMENTS IN PARTS TO BE ASSEMBLED

Modular unit for carrying and routing data or electronic information for data processing systems

The modular unit includes an electrical energy supply and a processor. There is an electronic card receiver bus, input and output connections and a hard disk storage. The unit has at least a first electronic card (4) defining one or more information or electronic functions. This receives or transmits signals to or from a second card (5) positioned on a front face of the modular unit. This defines the input and output connections of the first card (4) for connecting the appropriate tools to be used. The unit has a third card (3), called the mother card, to which the first card (4) and second card (5) are connected. The first card (4) is preferably called the daughter card. The mother card (3) defines the processing, for a central computer, of the signals received from the first card (4) and/or the second card (5). After processing the mother card transfers these signals back to the first (4) and second card (5).

Manually operated powder atomizer

Water-soluble agents having mitogenic properties obtained from nocardia cells, and processes for the preparation thereof

The invention pertains to a mitrogenic agent and to a process for obtaining same. It comprises the steps of cultivating Nocardiae cells, collecting them, subjecting them to a treatment for rupturing the integrity of their walls, such as by lysis, discarding the solid residue and collecting the aqueous fraction, causing the peptidoglycane fragments contained in this aqueous fraction to be separated therefrom and recovering the remaining fraction containing the mitogenic agent.

HIGH CALCIUM SUGAR FREE GEL

Aerosol atomizer device

Improvements in electrolysis processes and devices

Query-based identifiers for cross-session response tracking

Systems and methods for cross-session response tracking in a distributed computing environment using query identifiers generated based on search parameters. A search query including search parameters is received from a client device. A query identifier for the search query is generated based on the search parameters. One version of a search result among multiple versions of the search result is selected based on the query identifier and sent to the client device. A record in a transaction database is correlated with the selected version of the search result using the query identifier.

HIGH CALCIUM SUGAR FREE GEL

L'invention a pour objet un produit diététique ou pharmaceutique à haute teneur en calcium. Ce produit se présente sous la forme d'une pâte gélifiée sans sucre contenant de 100 à 500 mg de calcium par article unitaire.Elle concerne également son procédé de préparation ainsi que son utilisation en vue de pallier certaines déficiences alimentaires et de prévenir et combattre l'ostéoporose. The subject of the invention is a dietetic or pharmaceutical product with a high calcium content. This product is in the form of a sugar-free gelled paste containing 100 to 500 mg of calcium per unit item. It also relates to its preparation process and its use with a view to alleviating certain food deficiencies and preventing and combating 'osteoporosis.

Jack with articulation fork

The invention concerns a jack 3 with asymmetric longitudinal sides, comprising an articulation fork 19. The fork 19 is part of a support base 20 firmly connected to the jack 3. This fork 19 is offset in the direction of 18 on its support plate 20, laterally with respect to the longitudinal axis 22 of the jack 3, transversely with respect to its own axis of articulation 8. According to an advantageous embodiment, the support plate 20 of the articulation fork 19 is mounted such that it pivots about a shaft 23 supported by the jack, and provided with retaining means constituted by a washer 26. The screws 21 constitute the means of fixing the support plate 20. These means of fixing are adapted to firmly connect the jack 3 to the support plate 20 in either one of two symmetrical positions provided.

TOOLING FOR PLACING A CLUTCH SLEEVE AND KIT COMPRISING THE SAME

Pour la mise en place de douille (300) à clavette (320), l'outillage peut être monté sur un outil de vissage (100), et raccordé à une alimentation pneumatique. Il comporte un dispositif de transmission de couple de vissage (14, 52), pour visser la douille, et dans un carter (12), un dispositif de percussion de clavette (16), permettant de sertir la clavette sur la douille lorsqu'une pression de sertissage lui est appliquée par l'alimentation pneumatique.Le dispositif de percussion (16) comporte une pluralité de plateaux (18A, 18B, 18C) sensiblement perpendiculaires à l'axe de vissage. La pression de sertissage brutalement appliquée sur les plateaux à l'intérieur du carter (12), entraine le dispositif de percussion de clavette et permet le sertissage de celles-ci.L'outillage ne comprend pas de pièces mécaniques en mouvement et présente une grande fiabilité.L'invention vise également un kit comprenant un outillage de ce type et un outil de vissage. For the establishment of bushing (300) key (320), the tool can be mounted on a screwdriver (100), and connected to a pneumatic supply. It comprises a torque-transmitting device (14, 52) for screwing the sleeve, and in a housing (12) a key-percussion device (16) for crimping the key on the socket when a The crimping device (16) has a plurality of trays (18A, 18B, 18C) substantially perpendicular to the screw axis. The crimping pressure brutally applied to the trays inside the housing (12) drives the key percussion device and allows the crimping thereof.The tooling does not include moving mechanical parts and has a large reliability.The invention also relates to a kit comprising a tool of this type and a screwing tool.

Use of arsenic trioxide for the treatment of mammalian neoplastic disorders, especially chronic myeloid leukemia, adult T leukemia and lymphoid B proliferation

The use of arsenic trioxide in medicines for the treatment of mammalian neoplastic disorders. The specific disorders for which this treatment is effective are chronic myeloid leukemia, adult T leukemia due to HTLV-1 virus, and lymphoid proliferation. The As2O3 is preferably administered at a daily dosage of 0.1 - 0.2 mg/kg, especially 0.15 mg, as an injectable solution. For the treatment of T lymphoid leukemia due to HTLV-1, the As2O3 may be administered together with alpha -interferon in a separate form, simultaneously or staggered over a period. Independent claims are also included for injectable solutions for the treatment of the specific disorders listed, containing 0.1 - 2g/dl of As2O3, sodium cations, chloride anions, and having a pH in the range 5 - 7.

Affinity relationship based ecommerce

Data characterizing an offer for sale of a good or service by a seller is received. The data specifies constraints of the offer. The constraints identify a plurality of groups of potential buyers to which the offer is to be conveyed and characterizes conditions specifying how the offer is to be conveyed to each group. At least one of the groups is determined based on an affinity relationship of the potential buyers in that group to the seller. The terms of the offer may vary between at least two of the plurality of groups based on the relationship. A plurality of formatted offers can be generated. Each formatted offer corresponds to a respective group and to an online marketplace. At least one of the formatted offers can be posted to a respective group according to the conditions. Related apparatus, systems, techniques and articles are also described.

Dispenser with push button

USE OF A HEMOGLOBIN FOR THE PREPARATION OF DRESSINGS, AND DRESSINGS THUS PREPARED

La présente invention concerne l'utilisation d'une hémoglobine pour la préparation de pansements, et les pansements ainsi préparés. The present invention relates to the use of a hemoglobin for the preparation of dressings, and the dressings thus prepared.

IMPROVEMENTS TO THE DEVICES FOR THE EXCITATION OF THE SALIVARY SECRETION

The apparatus according to the invention is of the type comprising a source of autonomous direct current, of which each of the poles is connected to an electrode capable of being placed in the oral cavity, and the apparatus is characterised in that it consists of a dragee of general parallelepipedic shape which is flattened and has very rounded edges and comprises, on two opposite parallel main faces (2, 2'), a disc (3, 3') made of conductive material, each of the discs being connected to the poles [lacuna] a battery supplying a direct current and embedded in a hermetic seat (4) within the said dragee. The dragee is made of strong and alimentary resin (methacrylate) and the discs forming the electrodes are made of stainless steel; the dragee consists of two halves made integral by ultrasonic welding.

Aerosol-type dispenser for dispensing a powdered material

An aerosol-type dispenser for dispensing a powdered material. The dispenser has a propellant container, valve means operatively associated with said propellant container for controlling release of propellant from said propellant container, and a productcontaining chamber for containing the powdered material to be dispensed. A fluidization chamber is mounted on one end of said product-containing chamber and said product-containing chamber opens into it. The propellant container is mounted on said fluidization chamber and said valve means discharges into said fluidization chamber. The fluidization chamber has an outlet orifice therein, the propellant container is mounted on said fluidization chamber with the axis thereof at an oblique angle to the axis of said product-containing chamber, whereby when the dispenser is held with the product-containing chamber above the propellant-containing container, the powdered material is fed to the fluidization chamber by gravity.

Sprayer with waterproof nozzle with ultra-fast disassembly-reassembly

Method, device and computer program product for the geopositioning of a radio transmitter

INSTALLATION INCLUDING AT LEAST ONE PIVOTING LEAF AROUND A VERTICAL AXIS

Support device for single distillation column within the insulated enclosure

A support device for a single distillation column within an insulated enclosure is provided. The support device includes at least one fixed support (103) and at least one non-fixed supports (104). The non-fixed support device allows only one effective degree of local motion, in the direction of the first longitudinal axis.

Use of a haemoglobin for the preparation of dressings and resulting dressings

The invention relates to the use of a haemoglobin for the preparation of dressings and to the resulting dressings.

Fastener e.g. rivet, installing method for structural and/or decorative covering of aircraft, involves axially pushing fastener, by push-pull rod action to bring its head close to side opposite to outer part and to maintain its rod in holes

The method involves applying a body (5) against a side (3B) opposite to an outer part (3). A fastener (2) is axially pushed, by the action of a push-pull rod (6) sliding in a passage (5A), in a manner to bring its head close to the side opposite to the outer part and to maintain its rod (2B), by tight adjustment, in aligned holes of parts to be assembled, while free end of the fastener extends from an inner part. An independent claim is also included for a tool to implement a fastener installing method.

Sprayer with double opposed jets for automatic lubrication

VEHICLE IDENTIFICATION AND TRACKING DEVICE

TILT OR SECTIONAL DOOR ACTUATION INSTALLATION

L'INSTALLATION COMPREND UN BATI ALLONGE 2 SUPPORTANT UN ELEMENT MOBILE LINEAIREMENT 5 ENTRAINE PAR UNE VIS OU CHAINE RELIE A LA PORTE A ENTRAINER, ET FIXE EN DEUX POINTS HAUTS 9, 11 DONT L'UN 9 EST SITUE A UNE EXTREMITE DU BATI. CETTE EXTREMITE EST FIXEE A UN SUPPORT FIXE 9 PRESENTANT UNE DECOUPE VERTICALE DONT LE FOND PRESENTE UNE GORGE 17 DONT LA PARTIE SUPERIEURE EST LIMITEE PAR UNE SURFACE 18 SITUEE A UNE DISTANCE DETERMINEE DU FOND DE LA GORGE 17. LE BATI 2 PRESENTE UNE SURFACE D'APPUI, PAR EXEMPLE UN AXE 19, ET UNE SURFACE DE VERROUILLAGE, PAR EXEMPLE UN AXE 20, SITUE A UNE DISTANCE DU PREMIER AXE CORRESPONDANT A LADITE DISTANCE DETERMINEE. LE BATI SE FIXE PAR UNE SEULE PERSONNE PAR ACCROCHAGE DE L'AXE INFERIEUR AU SUPPORT PUIS LEVAGE A L'HORIZONTALE, CE QUI A POUR EFFET DE VERROUILLER AUTOMATIQUEMENT LA FIXATION.

Galena detector

Push-button dispenser

RECOVERY AND PROTECTOR OF WASTE OR FUMES GENERATED BY A STRUCTURE

Actuating arrangement of an up- and over or sectional door

This device for actuating a tip-up or sectional door comprises an elongated frame structure supporting a linearly movable member driven through a worm screw or a chain connected to the door to be driven, and secured at two upper points of which one is located at one end of the frame structure. This one end is secured to a fixed support formed with a vertical notch of which the bottom edge has a groove formed therein, the upper edge of this notch being limited by a surface located at a predetermined distance from the groove bottom. The frame structure comprises a support surface, for example in the form of a pin, and a locking surface, for example in the form of another pin, located at a distance from the first pin which corresponds to the predetermined distance. This frame structure can be fitted by a single person by anchoring the lower pin of the support and then raising the frame structure to a substantially horizontal position, so as to lock automatically the device in its operative position.

ELECTROMECHANICAL ACTUATING DEVICE FOR A SLIDING MOVEMENT DOOR

Electromechanical operating device for a slidingly movable door, which device comprises a motor driving a worm on which is mounted a nut connected to the door which is is to be moved, said nut being secured in respect of rotation by a slide guide having a step at the point corresponding to the end of the stroke of the door. This step allows a certain rotation of the nut and constitutes a stop preventing the rearward displacement of the nut when the latter is acted on by means of the door. The nut is composed of two parts axially fastened to one another and mounted for rotation one about the other, these parts being so shaped as to ensure that they will be fastened together in respect of rotation with considerable angular play. The aim of the device is to prevent untimely unlocking of the closed door through the elastic torsional cocking of the worm.

INSTALLATION MANUAL OF VIPIP OR FOLDING PORTS.

Method of framing images appearing on a fluorescent screen

Powder distribution device with a valve operated by a pusher

Combination of an anti-cancer agent such as a tyrosinekinase inhibitor and a stat5 antagonist, preferably a thiazolidinedione, for eliminating hematologic cancer stem cells in vivo and for preventing hematologic cancer relapse

Acid etch

transmission device and self-propelled machine equipped with such a transmission device

Dispositif (1) de transmission comprenant un boîtier (2) de transmission, un arbre (3) de sortie du boîtier s’étendant au moins partiellement en saillie du boîtier (2), un moteur (4) électrique équipé d’un arbre (5) moteur rotatif, une transmission (6) de mouvement de l’arbre (5) moteur à l’arbre (3) de sortie logée au moins partiellement à l’intérieur du boîtier (2) et accessible à l’arbre (5) moteur depuis l’extérieur du boîtier (2) via une ouverture (7) ménagée dans ledit boîtier (2), ledit moteur (4), extérieur au boîtier (2), présentant une surface (8) dite d’appui positionnable en appui contre le boîtier (2) à l’état en prise de l’arbre (5) moteur avec la transmission (6) de mouvement, ce moteur (4) étant protégeable par un capot (9) couplable au boîtier (2). Le dispositif (1) de transmission comprend un organe (10) élastiquement déformable de maintien de la surface (8) d’appui du moteur (4) en position d’appui contre le boîtier (2), cet organe (10) élastiquement déformable étant, à l’état couplé du capot (9) au boîtier (2), logé dans le capot (9). Figure pour l’abrégé : Fig. 3 Transmission device (1) comprising a transmission casing (2), an output shaft (3) from the casing extending at least partially projecting from the casing (2), an electric motor (4) equipped with a shaft ( 5) rotary motor, a transmission (6) of motion from the motor shaft (5) to the output shaft (3) housed at least partially inside the casing (2) and accessible to the shaft (5 ) motor from outside the housing (2) via an opening (7) made in said housing (2), said motor (4), outside the housing (2), having a so-called support surface (8) that can be positioned in bearing against the casing (2) in the state of engagement of the motor shaft (5) with the transmission (6) of movement, this motor (4) being protected by a cover (9) which can be coupled to the casing (2). The transmission device (1) comprises an elastically deformable member (10) for holding the bearing surface (8) of the motor ( ...

transmission box and its mounting method, and self-propelled machine equipped with such a transmission box

Boîtier (1) de transmission comprenant un arbre (5) de sortie réalisé en un seul tenant ou en au moins deux sections (5A, 5B) d’arbre, ledit arbre étant insérable dans le boîtier (2) à l'état fermé du boîtier (2) à travers au moins l’une (3) des ouvertures (3, 4) dite ouverture (3) d’introduction du boîtier (2), le boîtier (1) comprenant en outre au moins un dispositif (8) de limitation en déplacement axial de l’arbre (5) de sortie ou de la section (5A ; 5B) d’arbre de sortie, ce dispositif (8) de limitation en déplacement axial activable pour le passage d’un état inactif à un état actif dans lequel tout déplacement axial de l’arbre (5) de sortie ou de la section (5A ; 5B) d’arbre de sortie à l’intérieur du boîtier (1) suivant au moins une direction opposée à la direction d’introduction de l’arbre (5) de sortie ou de la section d’arbre de sortie dans le boîtier (1) est limité ou empêché est un dispositif (8) activable à l’état fermé du boîtier (1) est configuré pour, à l’état fermé du boîtier (1), passer d’un état inactif à un état actif, en fonction de la position occupée par l’arbre (5) de sortie ou ladite section (5A ; 5B) d’arbre de sortie dans ledit boîtier (1), par simple déplacement de l’arbre (5) de sortie ou de la section (5A ; 5B) d’arbre de sortie depuis la ou l’une des ouvertures (3) d’introduction du boîtier (1) en direction de l’intérieur du boîtier (1). Figure pour l’abrégé : Fig. 3 Transmission casing (1) comprising an output shaft (5) made in one piece or in at least two shaft sections (5A, 5B), said shaft being insertable into the casing (2) in the closed state of the housing (2) through at least one (3) of the openings (3, 4) called opening (3) for introducing the housing (2), the housing (1) further comprising at least one device (8) for limiting the axial displacement of the output shaft (5) or of the section (5A; 5B) of the output shaft, this device (8) for limiting the axial displacement which can be activated for the transition from an ...

IMPROVEMENTS IN BUTTON DISTRIBUTORS WITH SEPARATE PHASE PRESSURE

Improvements to films or film tapes for cinematographs

Improvements to discs, cylinders, etc., for talking machines, their recording mode and talking machines

LINEAR ACTUATOR WITH SCREW NUT SYSTEM

Ball cage for screw and nut assembly

The invention relates to a ball cage consisting of a cylindrical sleeve 1 provided with ball seats 7, 8 intended to receive balls 9, 10 intended to cooperate with a worm 11. The sleeve 1 is intended to be mounted in a cylindrical tube 2. The balls 9, 10 are retained in their seats on the one hand by a narrowed portion formed at the intersection of the perforations 7, 8 containing the balls and of a helicoidal bead 13 extending over the inner face of the cage, and on the other hand by projections 15 to 18 provided at the outer ends of the perforations. The balls are forced into their seats. The ball gage is used in the operation of doors or gates.

Use of a globin, a globin protomer or an extracellular hemoglobin for the preservation of organs, tissues, organ and tissue cells and cell cultures

The invention relates to the use of at least one globin and/or at least one globin protomer and/or at least one naturally extracellular native hemoglobin for the preservation of organs, tissues, organ and tissue cells and cell cultures.

Device for actuating a tip-up or sectional door

ABSTRACT OF THE DISCLOSURE This device for actuating a tip-up or sectional door com-prises an elongated frame structure supporting a linearly mo-vable member driven through a worm screw or a chain connected to the door to be driven, and secured at two upper points of which one is located at one and of the frame structure. This one end is secured to a fixed support formed with a vertical notch of which the bottom edge has a groove formed therein, the upper edge of this notch being limited by a surface lo-cated at a predetermined distance from the groove bottom. The frame structure comprises a bearing surface, for example in the form of a pin, and a locking surface, for example in the form of another pin, located at a distance from the first pin which corresponds to the predetermined distance. This frame structure can be fitted by a single person by anchoring the lower pin of the support and then raising the frame structure to a substantially horizontal position, so as to lock automa-tically the device in its operative position.

Patent DK130328C

Combination of an anti-cancer agent such as a tyrosinekinase inhibitor and a stat5 antagonist preferably a thiazolid nedione, for eliminating hematologic cancer stem cells in vivo and for preventing hematologic cancer relapse

Provided are methods for eliminating hematologic cancer stem cells in vivo, and thus preventing cancer relapse. The methods comprise a Signal Transducer and Activator of Transcription 5 (STAT5) antagonist (e.g., a PPARy agonist) after the patient has had ana initial course of treatment with an anti-cancer agent (e.g., a TKI), to eliminate residual cancer stem cells which cause relapse.

Dispositif de commande à percussion pour extincteur à pression auxiliaire et extincteur associé

L’invention concerne un dispositif de commande à percussion pour activer un extincteur à pression auxiliaire, ledit dispositif comportant un corps (3) de tête d’extincteur fixé sur une partie supérieure d’un réservoir (1), une poignée (4) d’actionnement manuel et un percuteur (5) mobile en translation par actionnement de la poignée (4). La poignée (4) est mobile en rotation autour d’un axe (6) d’articulation sur le corps (3) et porte une came (10) en contact avec le percuteur (5), et dont le profil permet, par rotation de la poignée (4) selon un premier sens, une translation du percuteur (5) jusqu’à une position d’activation dans le percuteur (5) perfore une cartouche (11) de gaz. Selon l’invention, le profil de came (10) est configuré pour permettre en outre ladite translation du percuteur (5) jusqu’à la position d’activation par rotation de la poignée (4) autour dudit axe (6) selon un deuxième sens opposé au premier sens. Figure pour l’abrégé : Fig. 2

Martinetto con giunto d'articolazione.

Eco-electrode, device storing electrical energy and process for preparation thereof

Eco-electrode, device storing electrical energy and process for preparation thereof The present invention relates to a composite electrode for a device storing electrical energy wherein said electrode comprises an electrode body and an electrode shell, wherein said body comprises at least one water-soluble polymer and wherein at least a part of said shell comprises a shell comprising at least one organic or organometallic material. The present invention also relates to a device storing electrical energy comprising said composite electrode and a process for preparing said composite electrode.

Eco-electrode, device storing electrical energy and process for preparation thereof

The present invention relates to a composite electrode for a device storing electrical energy wherein said electrode comprises an electrode body and an electrode shell, wherein said body comprises at least one water-soluble polymer and wherein at least a part of said shell comprises a shell comprising at least one organic or organometallic material.The present invention also relates to a device storing electrical energy comprising said composite electrode and a process for preparing said composite electrode.

Stage noise cabinet

Massnahme zur Verhinderung des Austretens von fluessigem Treibmittel aus einer Spruehvorrichtung zum Zerstaeuben eines fluessigen Produktes