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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 47. Отображено 47.
20-06-2016 дата публикации

Method for Bioconversing Organosulfur Compounds from Garlic

Номер: KR0101631315B1
Принадлежит: 한국식품연구원

... 본 발명은 (a) 마늘 분쇄체의 현탁액 또는 마늘 추출물에 효모를 접종시키는 단계; 및 (b) 상기 단계 (a)의 효모 접종 결과물을 배양하여 마늘의 유기황 화합물을 생물전환(biotransformation)시킴으로써 SAC[(+)-S-allyl-1-cystein)], SPC(S-trans-1-propenyl-L-cysteine) 및 SMC(S-methyl-cysteine)로 구성된 군으로부터 선택되는 하나 이상의 유기황 화합물을 인리치먼트(enrichment)시키는 단계를 포함하는 마늘의 유기황 화합물(organosulfur compounds)의 생물전환 방법에 관한 것이다. 본 발명은 마늘 내 유효한 유기황 화합물을 생물전환시켜 유기황 화합물의 효율을 개선할 수 있다.

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03-08-2016 дата публикации

락토바실러스 파라카제이(Lactobacillus paracasei)를 유효성분으로 포함하는 Th1-매개 면역 질환 또는 Th2-매개 면역 질환의 예방, 개선 또는 치료용 조성물

Номер: KR0101644595B1
Принадлежит: 한국식품연구원

... 본 발명은 락토바실러스 파라카제이(Lactobacillus paracasei)를 유효성분으로 포함하는 Th1-매개 면역 질환 또는 Th2-매개 면역 질환의 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명의 락토바실러스 파라카제이는 조절 T 세포를 활성화시키고, 항염증 사이토카인인 IL-10 생성을 증가시키며, 면역활성 사이토카인인 IL-12 생성을 억제시킴으로써 Th1-매개 면역 질환 또는 Th2-매개 면역 질환을 효과적으로 제어하는바 항알레르기성 조성물 및 항염증성 조성물로 사용이 가능한 이점이 있다.

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01-09-2016 дата публикации

사카로마이세스 세레비지애를 이용한 은행 외과피의 혐오취 저감 방법

Номер: KR0101652930B1
Принадлежит: 한국식품연구원

... 본 발명은 은행 외과피의 혐오취를 저감시킬수 있는 사카로마이세스 세레비지애 및 이를 이용하여 은행 외과피의 혐오취를 저감시키는 방법에 관한 것이다. 본 발명의 방법에 의할 경우 은행 외과피의 주요 혐오취 성분인 부티르산 및 헥산산의 함량을 감소시키고, 그 결과 은행 외과피의 혐오취를 저감시킬 수 있으며, 또한 혐오취가 저감된 은행 외과피 발효물을 제조할 수 있다.

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23-04-2018 дата публикации

NOVEL LACTOBACILLUS PLANTARUM LB41 STRAIN AND PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING OBESITY COMPRISING SAME

Номер: KR1020180040894A
Принадлежит:

The present invention relates to Lactobacillus plantarum Lb41 strain which is probiotics isolated from traditional fermented foods and a use of the same, and more specifically, to an anti-obesity use of the strain. According to the present invention, the Lactobacillus plantarum Lb41 strain isolated from traditional fermented foods such as kimchi may be used as probiotics; may suppress fat accumulation in adipocytes; and when administered in a mouse model for high-fat diet-induced obesity, may show the effect of significantly decreasing body fat, and thus the Lactobacillus plantarum Lb41 strain may be used as an active ingredient in a composition for preventing, treating and alleviating obesity. COPYRIGHT KIPO 2018 ...

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17-04-2017 дата публикации

COMPOSITION FOR PREVENTING, AMELIORATING OR TREATING Th1-MEDIATED IMMUNE DISEASES OR Th2-MEDIATED IMMUNE DISEASES COMPRISING BACILLUS AMYLOLIQUEFACIENS SUBSP. PLANTARUM AS ACTIVE INGREDIENT

Номер: KR1020170041337A
Принадлежит:

The present invention relates to a composition for preventing, ameliorating or treating Th1-mediated immune diseases or Th2-mediated immune diseases, the composition comprising Bacillus amyloliquefaciens subsp. plantarum as an active ingredient. The Bacillus amyloliquefaciens subsp. plantarum of the present invention activates regulatory T-cells; increases the production of anti-inflammatory cytokine IL-10; suppresses the production of immunoreactive cytokine IL-12; and reduces the production amount of IgE antibodies, thereby effectively controlling Th1-mediated immune diseases or Th2-mediated immune diseases, and thus may be beneficially used as an antiallergenic composition and an anti-inflammatory composition. COPYRIGHT KIPO 2017 ...

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17-04-2017 дата публикации

COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING Th1-MEDIATED IMMUNE DISEASES OR Th2-MEDIATED IMMUNE DISEASES COMPRISING STAPHYLOCOCCUS EPIDERMIDIS AS ACTIVE INGREDIENT

Номер: KR1020170041338A
Принадлежит:

The present invention relates to a composition which is used for preventing, ameliorating or treating Th1-mediated immune diseases or Th2-mediated immune diseases, and comprises a Staphylococcus epidermidis strain as an active ingredient. The Staphylococcus epidermidis KF814 of the present invention induces T-regulatory cells; controls the ratio of immunotolerant cytokine (IL-10, anti-inflammatory cytokine) to immunoreactive cytokine (IL-12); reduces the production of immunoglobulin E (IgE); and in case of immune hypersensitivity, reduces Th1-related cytokines and Th2-related cytokines, thereby effectively controlling allergy and inflammation, and thus may be beneficially used as an antiallergenic composition and an anti-inflammatory composition. COPYRIGHT KIPO 2017 ...

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16-11-2022 дата публикации

분홍바늘꽃 추출물을 유효성분으로 포함하는 호흡기 질환 개선용 조성물

Номер: KR102467856B1
Принадлежит: 한국식품연구원

... 본 발명은 분홍바늘꽃(Epilobium angustifolium L.) 추출물을 유효성분으로 포함하는 호흡기 기능 강화 및 호흡기 질환 개선용 식품 조성물; 상기 식품 조성물을 포함하는 건강기능식품; 및 분홍바늘꽃 추출물을 유효성분으로 포함하는 호흡기 질환 예방 또는 치료용 약제학적 조성물에 관한 것이다. 본 발명의 분홍바늘꽃 추출물은 호중구 세포외 트랩(Neutrophil extracellular traps)의 네토시스(Netosis) 활성화를 억제하고, 기관지 상피세포주 NCI-H292 세포의 CSE(Cigarette Smoke Extraction)에 의한 염증성 사이토카인 발현을 억제하며, CSE와 PPE로 유도된 호흡기 질환 마우스 모델에서 폐 조직 손상을 억제하고, BALF 내 총 세포, 대식세포, 림프구, 호산구, 호중구 등 면역세포 침윤을 억제하며, BALF 및 폐 조직에서 염증성 사이토카인과 케모카인 분비를 억제하는 활성을 나타낸다.

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07-03-2019 дата публикации

COMPOSITION COMPRISING MIQUELIANIN AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING TH2-MEDIATED IMMUNE DISEASE

Номер: WO2019045286A2
Принадлежит:

The present invention relates to a composition comprising miquelianin as an effective ingredient for preventing, alleviating, or treating Th2-mediated immune diseases. A composition according to the present invention was found to have an excellent anti-allergic effect. In greater detail, miquelianin was identified to restrain the generation of interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-5 (IL-5), and/or interleukin-13 (IL-13) as tested for anti-allergic effect in vivo and ex vivo. Also, miquelianin was found to have the effect of producing IgE and preventing T cell proliferation. Therefore, the composition according to the present invention is expected to find useful applications in the development of a therapeutic agent, a health functional food, and a cosmetic product for prevention, alleviation, or treatment of Th2-mediated immune diseases.

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25-04-2019 дата публикации

COMPOSITION COMPRISING FRACTION OF ROSA MULTIFLORA EXTRACT AS EFFECTIVE INGREDIENT FOR PREVENTING, ALLEVIATING, OR TREATING IMMUNE DISEASE

Номер: WO2019045287A3
Принадлежит:

The present invention relates to a composition comprising a fraction of a Rosa multiflora extract as an effective ingredient for preventing, alleviating, or treating immune diseases. According to the present invention, a fraction of a Rosa multiflora extract is identified to restrain the generation of interleukin 4 (IL-4) and can thus prevent, alleviate, or treat Th2-mediated immune diseases.

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11-01-2018 дата публикации

해조류 분해 활성을 갖는 신규한 쉬와넬라 속 균주 및 이의 용도

Номер: KR0101817303B1
Принадлежит: 한국식품연구원

... 본 발명은 해조류 또는 해조 다당류 분해 활성을 가지며, 홍삼(Apostichopus japonicus)의 장에서 분리된 쉬와넬라 속(Shewanella sp.) 균주, 해조류 또는 해조 다당류 분해용 조성물 및 해조류 또는 해조 다당류 분해 방법을 제공한다. 본 발명에 따르면, 본 발명의 신규 쉬와넬라 속 균주는 해조류(특히, 홍조류) 및 다양한 해조 다당류를 분해할 수 있고, 해조류 및 해조 다당류 분해 효소를 분비한다. 따라서 해조류 및 해조 다당류 분해에 본 발명의 균주를 이용하는 경우, 열수, 알칼리 또는 산처리가 요구되지 않고, 유기용매를 사용하지 않는바, 해조류의 유용성분이 변질 또는 파괴되지 않고, 공정이 단순해지며, 환경오염을 시키지 않는 이점이 있다.

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18-04-2019 дата публикации

COMPOSITION COMPRISING MIQUELIANIN AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING TH2-MEDIATED IMMUNE DISEASE

Номер: WO2019045286A3
Принадлежит:

The present invention relates to a composition comprising miquelianin as an effective ingredient for preventing, alleviating, or treating Th2-mediated immune diseases. A composition according to the present invention was found to have an excellent anti-allergic effect. In greater detail, miquelianin was identified to restrain the generation of interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-5 (IL-5), and/or interleukin-13 (IL-13) as tested for anti-allergic effect in vivo and ex vivo. Also, miquelianin was found to have the effect of producing IgE and preventing T cell proliferation. Therefore, the composition according to the present invention is expected to find useful applications in the development of a therapeutic agent, a health functional food, and a cosmetic product for prevention, alleviation, or treatment of Th2-mediated immune diseases.

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07-07-2016 дата публикации

Compositions for Preventing, Improving, or Treating Liver Disorders Comprising Substances of Fermented Soy Bean Using Bacillus subtilis subsp. inaquosorum as an Active Ingredient

Номер: KR0101635987B1
Принадлежит: 한국식품연구원

... 본 발명은 바실러스 서브틸리스 인아쿠오소럼 아종(Bacillussubtilis subsp. inaquosorum)에 의한 콩 발효물을 유효성분으로 포함하는 간 질환(liver disorders) 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명의 바실러스 서브틸리스 인아쿠오소럼 아종에 의한 콩 발효물은 α-SMA 발현억제활성을 가짐으로써 간 섬유화를 억제할 수 있어 간 질환 예방, 개선 또는 치료용 조성물로 사용이 가능한 이점이 있다.

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07-02-2018 дата публикации

PHARMACEUTICAL COMPOSITION COMPRISING BENTONITE AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASE

Номер: KR1020180013568A
Принадлежит:

The present invention relates to a pharmaceutical composition comprising bentonite which is clay mineral as an active ingredient for preventing or treating inflammatory bowel diseases. The composition comprising bentonite as an active ingredient of the present invention inhibits damage of bowel tissue and bleeding in the rectum to decrease bloody excrement, thereby being usefully used as a medicine and a health functional food for preventing, alleviating or treating inflammatory bowel diseases. COPYRIGHT KIPO 2018 ...

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24-03-2016 дата публикации

COMPOSITION COMPRISING GARLIC-FERMENTED PRODUCT USING MONASCUS PILOSUS

Номер: KR1020160032365A
Принадлежит:

The present invention relates to a composition comprising a garlic-fermented product using Monascus pilosus and, more specifically, to a pharmaceutical composition for preventing or treating insulin resistance and insulin resistance related diseases, and to a functional food composition for preventing or alleviating insulin resistance and insulin resistance related diseases. The pharmaceutical composition and functional food composition comprise a garlic-fermented product, as an active ingredient, by inoculating Monascus pilosus into a suspension of a garlic crushed body or a garlic extract, and then being fermented. In addition, the compositions of the present invention have effects of promoting sugar receptor expression, improving sugar absorption, controlling blood sugar, and controlling weight. COPYRIGHT KIPO 2016 ...

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23-10-2015 дата публикации

METHOD FOR BIOTRANSFORMING ORGANOSULFUR COMPOUNDS OF GARLIC

Номер: KR1020150118657A
Принадлежит:

The present invention relates to a method for biotransforming organosulfur compounds of garlic, which comprises the following steps: (a) inoculating yeast in suspension of garlic pulverized material or in garlic extract; and (b) culturing a yeast inoculated product from Step (a), biotransforming organosulfur compounds of garlic, and enriching one or more organosulfur compounds selected from the group consisting of SAC[(+)-S-allyl-1-cystein)], SPC(S-trans-1-propenyl-L-cysteine), and SMC(S-methyl-cysteine). According to the present invention, organosulfur compounds that are effective in garlic can be biotransformed, so effects of organosulfur compounds can be improved. COPYRIGHT KIPO 2016 ...

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07-07-2016 дата публикации

Compositions for Preventing, Improving, or Treating Liver Disorders Comprising Substances of Fermented Soy Bean Using Bacillus amyloliquefaciens as an Active Ingredient

Номер: KR0101635982B1
Принадлежит: 한국식품연구원

... 본 발명은 바실러스 아밀로리퀴페시언스(Bacillusamyloliquefaciens)에 의한 콩 발효물을 유효성분으로 포함하는 간 질환(liver disorders) 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명의 바실러스 아밀로리퀴페시언스에 의한 콩 발효물은 α-SMA 발현억제활성을 가짐으로써 간 섬유화를 억제할 수 있어 간 질환 예방, 개선 또는 치료용 조성물로 사용이 가능한 이점이 있다.

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12-03-2020 дата публикации

COMPOSITION FOR IMPROVING RESPIRATORY DISEASE INCLUDING EXTRACT OF PALIURUS RAMOSISSIMUS (LOUR.) POIR.

Номер: WO2020050633A1
Принадлежит:

The present invention discloses a composition for alleviating lung diseases, such as asthma and chronic obstructive pulmonary disease, using the extracts of Paliurus ramosissimus (Lour.) Poir, Rosa davurica Pall., Picrasma quassioides, Camellia sinensis, Chrysosplenium grayanum, Reynoutria japonica, Pseudocydonia sinensis, Hydrangea serrata, and/or Euonymus alatus. The extracts of Paliurus ramosissimus (Lour.) Poir, Rosa davurica Pall., Picrasma quassioides, Camellia sinensis, Chrysosplenium grayanum, Reynoutria japonica, Pseudocydonia sinensis, Hydrangea serrata, and/or Euonymus alatus have the activities of inhibiting the netosis activation of neutrophil extracellular traps induced by phorbol myristate acetate (PMA), inhibiting the expression of IL-8, an inflammatory cytokine by CSE of NCI-H292 cells, a bronchial epithelial cell line producing mucus, and inhibiting the expression of MIP-2, an inflammatory cytokine of alveolar macrophages MH-S cells activated by CES and LPS (lipopolysaccaride ...

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16-02-2017 дата публикации

COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING TH1-MEDIATED IMMUNE DISEASES, TH17-MEDIATED IMMUNE DISEASES, OR TH2-MEDIATED IMMUNE DISEASES, CONTAINING, AS ACTIVE INGREDIENT, LACTOBACILLUS PENTOSUS

Номер: WO2017026620A1
Принадлежит:

The present invention relates to: a Lactobacillus pentosus KF340 strain (deposit number KCCM 11675P); and a composition for preventing, alleviating, or treating Th1-mediated immune diseases, Th17-mediated immune diseases, or Th2-mediated immune diseases, containing the strain as an active ingredient. The novel Lactobacillus pentosus KF340 strain according to the present invention effectively controls allergies and inflammation by inducing regulatory T cells and regulatory B cells, controlling the ratio of an immune tolerant cytokine (IL-10; anti-inflammatory cytokine) to an immune activating cytokine (IL-12), inhibiting the generation of immunoglobulin E (IgE), inhibiting the generation of Th1-related cytokines, Th17-related cytokines, and Th2-related cytokines during immune hypersensitivity reactions, and promoting gut immune reactions according to the secretion of IgA. Therefore, the strain is expected to be usable as a composition for preventing, alleviating, or treating Th1-mediated ...

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02-09-2016 дата публикации

비피도박테리움 롱검을 이용한 은행 외과피의 혐오취 저감 방법

Номер: KR0101652949B1
Принадлежит: 한국식품연구원

... 본 발명은 은행 외과피의 혐오취를 저감시킬수 있는 비피도박테리움 롱검 및 이를 이용하여 은행 외과피의 혐오취를 저감시키는 방법에 관한 것이다. 본 발명의 방법에 의할 경우 은행 외과피의 주요 혐오취 성분인 부티르산 및 헥산산의 함량을 감소시키고, 그 결과 은행 외과피의 혐오취를 저감시킬 수 있으며, 또한 혐오취가 저감된 은행 외과피 발효물을 제조할 수 있다.

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25-01-2016 дата публикации

METHOD OF REDUCING STINK IN EPICARP OF GINKGO BILOBA USING DRYING TREATMENT

Номер: KR0101588286B1
Принадлежит: 한국식품연구원

... 본 발명은 은행 외과피를 건조 처리하는 것을 포함하는 은행 외과피의 혐오취를 저감시키는 방법에 관한 것이다. 본 발명의 방법에 의할 경우 은행 외과피의 주요 혐오취 성분인 부티르산 함량을 감소시키고, 그 결과 은행 외과피의 혐오취를 저감시킬 수 있다.

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20-01-2016 дата публикации

METHOD FOR REDUCING OFFENSIVE ODOR IN EXOCARP OF GINKGO BILOBA USING LACTOBACILLUS BREVIS

Номер: KR1020160006882A
Принадлежит:

The present invention relates to Lactobacillus brevis which can reduce offensive odor in an exocarp of Ginkgo biloba, and to a method for reducing offensive odor in an exocarp of Ginkgo biloba using the Lactobacillus brevis. According to the method of the present invention, butyric acid and hexanoic acid contents are reduced, wherein the butyric acid and hexanoic acid are main offensive odor ingredients in the exocarp of Ginkgo biloba, and thus offensive odor in the exocarp of Ginkgo biloba can be reduced. In addition, a fermented product using the exocarp of Ginkgo biloba can be produced, wherein the offensive odor is reduced in the fermented product. COPYRIGHT KIPO 2016 (AA) Cell viability ...

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02-03-2016 дата публикации

COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING LIVER DISORDERS, COMPRISING FERMENTED SOYBEAN PRODUCT GENERATED BY USING BACILLUS ARYABHATTAI, AS ACTIVE INGREDIENT

Номер: KR1020160022424A
Принадлежит:

The present invention relates to a composition for preventing, alleviating or treating liver disorders, comprising a fermented soybean product generated by using Bacillus aryabhattai, as an active ingredient. The fermented soybean product generated by using Bacillus aryabhattai of the present invention inhibits hepatic fibrosis by having alpha-SMA expression inhibiting activity, thereby having advantages of preventing, alleviating or treating liver disorders. COPYRIGHT KIPO 2016 (AA) Control group (BB) Fast-fermented bean paste (CC) Silymarin ...

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20-01-2016 дата публикации

METHOD FOR REDUCING OFFENSIVE ODOR IN EXOCARP OF GINKGO BILOBA USING ENTEROCOCCUS FAECIUM

Номер: KR1020160006877A
Принадлежит:

The present invention relates to Enterococcus faecium which can reduce offensive odor in an exocarp of Ginkgo biloba, and to a method for reducing offensive odor in an exocarp of Ginkgo biloba using the Enterococcus faecium. According to the method of the present invention, butyric acid and hexanoic acid contents are reduced, wherein the butyric acid and hexanoic acid are main offensive odor ingredients in the exocarp of Ginkgo biloba, and thus offensive odor in the exocarp of Ginkgo biloba can be reduced. In addition, a fermented product using the exocarp of Ginkgo biloba can be produced, wherein the offensive odor is reduced in the fermented product. COPYRIGHT KIPO 2016 (AA) Cell viability ...

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20-01-2016 дата публикации

METHOD FOR REDUCING OFFENSIVE ODOR IN EXOCARP OF GINKGO BILOBA USING BIFIDOBACTERIUM LONGUM

Номер: KR1020160006875A
Принадлежит:

The present invention relates to Bifidobacterium longum which can reduce offensive odor in an exocarp of Ginkgo biloba, and to a method for reducing offensive odor in an exocarp of Ginkgo biloba using the Bifidobacterium longum. According to the method of the present invention, butyric acid and hexanoic acid contents are reduced, wherein the butyric acid and hexanoic acid are main offensive odor ingredients in the exocarp of Ginkgo biloba, and thus offensive odor in the exocarp of Ginkgo biloba can be reduced. In addition, a fermented product using the exocarp of Ginkgo biloba can be produced, wherein the offensive odor is reduced in the fermented product. COPYRIGHT KIPO 2016 (AA) Cell survival rate ...

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07-07-2016 дата публикации

Compositions for Preventing, Improving, or Treating Liver Disorders Comprising Substances of Fermented Soy Bean Using Bacillus aryabhattai as an Active Ingredient

Номер: KR0101635985B1
Принадлежит: 한국식품연구원

... 본 발명은 바실러스 아리아바타이(Bacillus aryabhattai)에 의한 콩 발효물을 유효성분으로 포함하는 간 질환(liver disorders) 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명의 바실러스 아리아바타이에 의한 콩 발효물은 α-SMA 발현억제활성을 가짐으로써 간 섬유화를 억제할 수 있어 간 질환 예방, 개선 또는 치료용 조성물로 사용이 가능한 이점이 있다.

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01-09-2016 дата публикации

락토바실러스 사케이를 이용한 은행 외과피의 혐오취 저감 방법

Номер: KR0101652932B1
Принадлежит: 한국식품연구원

... 본 발명은 은행 외과피의 혐오취를 저감시킬수 있는 락토바실러스 사케이 및 이를 이용하여 은행 외과피의 혐오취를 저감시키는 방법에 관한 것이다. 본 발명의 방법에 의할 경우 은행 외과피의 주요 혐오취 성분인 부티르산 및 헥산산의 함량을 감소시키고, 그 결과 은행 외과피의 혐오취를 저감시킬 수 있으며, 또한 혐오취가 저감된 은행 외과피 발효물을 제조할 수 있다.

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02-03-2016 дата публикации

COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING LIVER DISORDERS, COMPRISING FERMENTED SOYBEAN PRODUCT GENERATED BY USING BACILLUS SUBTILIS SUBSP. INAQUOSORUM, AS ACTIVE INGREDIENT

Номер: KR1020160022425A
Принадлежит:

The present invention relates to a composition for preventing, alleviating or treating liver disorders, comprising a fermented soybean product generated by using Bacillus subtilis subsp. inaquosorum, as an active ingredient. The fermented soybean product generated by using Bacillus subtilis subsp. inaquosorum of the present invention inhibits hepatic fibrosis by having alpha-SMA expression inhibiting activity, thereby having advantages of preventing, alleviating or treating liver disorders. COPYRIGHT KIPO 2016 (AA) Control group (BB) Fast-fermented bean paste (CC) Silymarin ...

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23-08-2022 дата публикации

페디오코쿠스 펜토사세우스를 이용한 호흡기 기능 개선용 식품 조성물

Номер: KR102434641B1
Принадлежит: 한국식품연구원

... 본 발명은 페디오코쿠스 펜토사세우스(Pediococcus pentosaceus)를 이용한 염증, 만성폐쇄성폐질환 등의 폐질환 개선용 조성물을 개시한다. 페디오코쿠스 펜토사세우스(Pediococcus pentosaceus)는 COPD 동물모델에서 폐 세척액 내에서 주요 병인으로 관여하는 호중구, 대식세포 등의 염증세포의 수를 현저히 감소시키고, 폐 세척액와 폐 조직에서 IL-6, IL-1β, IL-17, TNF-α, IFN-γ, GM-CSF, MIP-2, KC, TARC, MCP-1, MDC 등의 염증성 사이토카인 및 케모카인의 발현을 억제함으로써 호흡기 질환 개선활성을 가진다.

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25-07-2017 дата публикации

락토바실러스 펜토서스를 유효성분으로 포함하는 Th1-매개 면역 질환, Th17-매개 면역 질환, 또는 Th2-매개 면역 질환의 예방, 개선, 또는 치료용 조성물

Номер: KR0101761506B1
Принадлежит: 한국식품연구원

... 본 발명은 락토바실러스 펜토서스(Lactobacillus pentosus) KF340 균주(수탁번호 KCCM 11675P) 및 상기 균주를 유효성분으로 포함하는 Th1-매개 면역 질환, Th17-매개 면역 질환, 또는 Th2-매개 면역 질환의 예방, 개선, 또는 치료용 조성물에 관한 것이다. 본 발명에 따른 신규한 락토바실러스 펜토서스 KF340 균주는 조절 T 세포 및 조절 B 세포 유도, 면역 활성 사이토카인(IL-12)에 대한 면역 관용 사이토카인(IL-10; 항염증성 사이토카인)의 비율 조절, 면역글로불린 E(IgE) 생성 억제, 면역과민반응 시 Th1 관련 사이토카인, Th17 관련 사이토카인, 및 Th2 관련 사이토카인의 생성 억제, 및 IgA 분비에 따른 장관면역반응 증진에 의하여 알레르기 및 염증을 효과적으로 제어하는바, Th1-매개 면역 질환, Th17-매개 면역 질환, 또는 Th2-매개 면역 질환, 더욱 바람직하게는 알레르기 또는 염증 질환의 예방, 개선, 또는 치료용 조성물로 유용하게 이용될 수 있을 것으로 기대된다.

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02-09-2016 дата публикации

엔테로코커스 페시움을 이용한 은행 외과피의 혐오취 저감 방법

Номер: KR0101652940B1
Принадлежит: 한국식품연구원

... 본 발명은 은행 외과피의 혐오취를 저감시킬수 있는 엔테로코커스 페시움 및 이를 이용하여 은행 외과피의 혐오취를 저감시키는 방법에 관한 것이다. 본 발명의 방법에 의할 경우 은행 외과피의 주요 혐오취 성분인 부티르산 및 헥산산의 함량을 감소시키고, 그 결과 은행 외과피의 혐오취를 저감시킬 수 있으며, 또한 혐오취가 저감된 은행 외과피 발효물을 제조할 수 있다.

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07-02-2018 дата публикации

ANTI-OBESITY COMPOSITION COMPRISING BENTONITE AS ACTIVE INGREDIENT

Номер: KR1020180013571A
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating obesity comprising bentonite which is clay mineral as an effective component. An effect of inhibiting adipose differentiation was confirmed in 3T3-L1 which is a preadipocyte cell through bentonite. Also, body weight loss, body fat reduction, leptin blood concentration decrease and body lipid emission effects were confirmed in an animal model where obesity is induced by high fat diet. Accordingly, the composition of the present invention can be effectively used for alleviating, preventing and treating obesity. COPYRIGHT KIPO 2018 ...

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25-05-2017 дата публикации

NOVEL BACILLUS SP. STRAIN HAVING CODIUM FRAGILE DEPOSITION ACTIVITY AND USES THEREOF

Номер: KR1020170057520A
Принадлежит:

The present invention provides a novel bacillus sp. strain having Codium fragile deposition activity, a Codium fragile deposition enzyme, a composition for decomposing the Codium fragile, and a method for decomposing the Codium fragile. According to the present invention, the Codium fragile deposition enzyme can directly decompose the Codium fragile, and can decompose various mannan oligosaccharides. When the strain or the Codium fragile deposition enzyme is used for decomposition of the Codium fragile and the mannan oligosaccharides, hot water, alkali or acid treatment are not required, and as no organic solvent is used, effective components are not altered or destroyed, and processes become simple, while having no influence on environmental pollution. COPYRIGHT KIPO 2017 (AA) Condium fragile of 1g ...

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01-08-2018 дата публикации

NOVEL STRAIN OF LACTOBACILLUS BREVIS G1 AND COMPOSITION FOR PREVENTING OR TREATING FOOD ALLERGY COMPRISING SAME

Номер: KR101884326B1

The present invention relates to a strain of Lactobacillus brevis G1 having the accession number of KCCM11898P having a food allergy inhibitory activity and to a composition for preventing, treating or alleviating food allergy comprising the strain as an active ingredient. COPYRIGHT KIPO 2018 ...

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02-03-2016 дата публикации

COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING LIVER DISORDERS, COMPRISING FERMENTED SOYBEAN PRODUCT GENERATED BY USING BACILLUS AMYLOLIQUEFACIENS, AS ACTIVE INGREDIENT

Номер: KR1020160022423A
Принадлежит:

The present invention relates to a composition for preventing, alleviating or treating liver disorders, comprising a fermented soybean product generated by using Bacillus amyloliquefaciens, as an active ingredient. The fermented soybean product generated by using Bacillus amyloliquefaciens of the present invention inhibits hepatic fibrosis by having alpha-SMA expression inhibiting activity, thereby having advantages of preventing, alleviating or treating liver disorders. COPYRIGHT KIPO 2016 (AA) Control group (BB) Fast-fermented bean paste (CC) Silymarin ...

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20-01-2016 дата публикации

METHOD FOR REDUCING OFFENSIVE ODOR IN EXOCARP OF GINKGO BILOBA USING SACCHAROMYCES CEREVISIAE

Номер: KR1020160006884A
Принадлежит:

The present invention relates to Saccharomyces cerevisiae which can reduce offensive odor in an exocarp of Ginkgo biloba, and to a method for reducing offensive odor in an exocarp of Ginkgo biloba using the Saccharomyces cerevisiae. According to the method of the present invention, butyric acid and hexanoic acid contents are reduced, wherein the butyric acid and hexanoic acid are main offensive odor ingredients in the exocarp of Ginkgo biloba, and thus offensive odor in the exocarp of Ginkgo biloba can be reduced. In addition, a fermented product using the exocarp of Ginkgo biloba can be produced, wherein the offensive odor is reduced in the fermented product. COPYRIGHT KIPO 2016 (AA) Cell viability ...

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03-11-2016 дата публикации

모나스커스 필로서스를 이용한 마늘 발효물을 포함하는 조성물

Номер: KR0101672007B1
Принадлежит: 한국식품연구원

... 본 발명은 모나스커스 필로서스(Monascus pilosus)를 이용한 마늘 발효물을 포함하는 조성물에 관한 것으로, 마늘 분쇄체의 현탁액 또는 마늘 추출물에 모나스커스 필로서스를 접종하여 발효시킨 마늘 발효물을 유효성분으로 포함하는 인슐린 저항성 또는 인슐린 저항성 관련 질환의 예방 또는 치료용 약제학적 조성물 및 예방 또는 개선용 기능성 식품 조성물을 제공한다. 본 발명의 조성물은 당수용체 발현 증진 효과, 당흡수 향상 효과, 혈당 조절 효과 및 체중 조절 효과를 갖는다.

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22-02-2017 дата публикации

COMPOSITION INCLUDING LACTOBACILLUS PENTOSUS AS ACTIVE INGREDIENT AND PREVENTING, ALLEVIATING, OR TREATING Th1-MEDIATED IMMUNE DISEASE, Th17-MEDIATED IMMUNE DISEASE, OR Th2-MEDIATED IMMUNE DISEASE

Номер: KR1020170020204A
Принадлежит:

The present invention relates to a Lactobacillus pentosus KF340 strain (donation number: KCCM 11675P), and to a composition for preventing, alleviating, or treating a Th1-mediated immune disease, a Th17-mediated immune disease, or a Th2-mediated immune disease, wherein the composition includes the strain as an active ingredient. The novel Lactobacillus pentosus KF340 strain according to the present invention effectively controls allergy and inflammation by inducing regulator T cells and regulator B cells, adjusting the rates of immunologic tolerance cytokine (IL-10, anti-inflammatory cytokine) with respect to immunoactive cytokine (IL-12), inhibiting the generation of immunoglobulin E (IgE), inhibiting the generation of Th1-related cytokine, Th17-related cytokine, and Th2-related cytokine during a hypersensitivity reaction, and improving mucosal immunity according to the secretion of IgA. Thus, it is expected that the strain can be useful as a composition for preventing, alleviating, or ...

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20-01-2016 дата публикации

METHOD FOR REDUCING OFFENSIVE ODOR IN EXOCARP OF GINKGO BILOBA USING LACTOBACILLUS SAKEI

Номер: KR1020160006883A
Принадлежит:

The present invention relates to Lactobacillus sakei which can reduce offensive odor in an exocarp of Ginkgo biloba, and to a method for reducing offensive odor in an exocarp of Ginkgo biloba using the Lactobacillus sakei. According to the method of the present invention, butyric acid and hexanoic acid contents are reduced, wherein the butyric acid and hexanoic acid are main offensive odor ingredients in the exocarp of Ginkgo biloba, and thus offensive odor in the exocarp of Ginkgo biloba can be reduced. In addition, a fermented product using the exocarp of Ginkgo biloba can be produced, wherein the offensive odor is reduced in the fermented product. COPYRIGHT KIPO 2016 (AA) Cell viability ...

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02-08-2018 дата публикации

벤토나이트를 유효성분으로 포함하는 염증성 장 질환의 예방 또는 치료용 약학적 조성물

Номер: KR0101884520B1

... 본 발명은 점토광물인 벤토나이트를 유효성분으로 포함하는 염증성 장 질환의 예방 또는 치료용 약학적 조성물에 관한 것이다. 본 발명의 벤토나이트를 유효성분으로 포함하는 조성물은 장 조직의 손상 및 직장 내 출혈을 억제시켜 혈변 증상을 감소시키는 효과를 확인한바, 염증성 장 질환의 예방, 개선 또는 치료용 의약품 및 건강기능식품으로 유용하게 사용될 수 있을 것으로 기대된다.

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25-01-2016 дата публикации

METHOD OF REDUCING STINK IN EPICARP OF GINKGO BILOBA USING HYDROTHERMAL TREATMENT

Номер: KR0101588291B1
Принадлежит: 한국식품연구원

... 본 발명은 은행 외과피를 열수 처리하는 것을 포함하는 은행 외과피의 혐오취를 저감시키는 방법에 관한 것이다. 본 발명의 방법에 의할 경우 은행 외과피의 주요 혐오취 성분인 부티르산 함량을 감소시키고, 그 결과 은행 외과피의 혐오취를 저감시킬 수 있다.

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23-02-2017 дата публикации

습열 처리를 이용한 은행 외과피의 혐오취 저감 방법

Номер: KR0101709664B1
Принадлежит: 한국식품연구원

... 본 발명은 은행 외과피를 습열 처리하는 것을 포함하는 은행 외과피의 혐오취를 저감시키는 방법에 관한 것이다. 본 발명의 방법에 의할 경우 은행 외과피의 주요 혐오취 성분인 부티르산 함량을 감소시키고, 그 결과 은행 외과피의 혐오취를 저감시킬 수 있다.

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25-05-2017 дата публикации

NOVEL SHEWANELLA STRAIN WITH SEAWEED DECOMPOSING ACTIVITY AND USE THEREOF

Номер: KR1020170057518A
Принадлежит:

The present invention relates to Shewanella strains separated from red ginseng (Apostichopus japonicus) while having an activity of decomposing polysaccharides from seaweeds, a composition for decomposing seaweeds or seaweed polysaccharides, and a decomposition method thereof. According to the present invention, the novel Shewanella strains can decompose various seaweed polysaccharides and seaweeds (especially red algae) and secreting enzymes for decomposing the seaweeds and seaweed polysaccharides. Accordingly, the Shewanella strains can be used to decompose the seaweeds and the seaweed polysaccharides without hot water, alkali or acid treatment processes, and organic solvents, thereby simplifying the process without environmental contamination and damage on the beneficial components of the seaweeds. COPYRIGHT KIPO 2017 (AA) Separated strain injection (BB) Laver (CC) Sea string (DD) Kelp (EE) Seaweed ...

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28-11-2019 дата публикации

COMPOSITION FOR ALLEVIATING ASTHMA OR CHRONIC OBSTRUCTIVE PULMONARY DISEASE BY USING EPILOBIUM PYRRICHOLOPHUM EXTRACT AND LIKE

Номер: WO2019225995A1
Принадлежит:

Disclosed in the present invention is a composition for alleviating asthma or chronic obstructive pulmonary disease by using a Epilobium pyrricholophum extract and the like that: inhibit NETosis induced by phorbol myristate acetate (PMA); inhibit the expression of inflammatory cytokines IL-6 and IL-8 in H292 cells, which are the bronchial epithelial cell line and are stimulated by cigarette smoke extract (CSE), porcine pancreas elastase (PPE) and ultrafine dust that is 2.5 micrometers or less in diameter (PM2.5); inhibit the expression of inflammatory cytokine MIP2 (IL-8) that are also in MH-S cells, which are mouse alveolar macrophages and are activated by CES; reduce the number of neutrophils and the like in BALF during animal model experimentation in which COPD is induced by using CES and PPE; and reduce, in BALF or lung tissues, the concentration of inflammatory cytokines such as MIP-2, TNF-α, IL-1β, IL-6, KC, MCP-1 and IFN-γ and the concentration of MDC, GM-CSF, IL-17 and the like.

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07-03-2019 дата публикации

COMPOSITION COMPRISING FRACTION OF ROSA MULTIFLORA EXTRACT AS EFFECTIVE INGREDIENT FOR PREVENTING, ALLEVIATING, OR TREATING IMMUNE DISEASE

Номер: WO2019045287A2
Принадлежит:

The present invention relates to a composition comprising a fraction of a Rosa multiflora extract as an effective ingredient for preventing, alleviating, or treating immune diseases. According to the present invention, a fraction of a Rosa multiflora extract is identified to restrain the generation of interleukin 4 (IL-4) and can thus prevent, alleviate, or treat Th2-mediated immune diseases.

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02-09-2016 дата публикации

락토바실러스 브레비스를 이용한 은행 외과피의 혐오취 저감 방법

Номер: KR0101652945B1
Принадлежит: 한국식품연구원

... 본 발명은 은행 외과피의 혐오취를 저감시킬수 있는 락토바실러스 브레비스 및 이를 이용하여 은행 외과피의 혐오취를 저감시키는 방법에 관한 것이다. 본 발명의 방법에 의할 경우 은행 외과피의 주요 혐오취 성분인 부티르산 및 헥산산의 함량을 감소시키고, 그 결과 은행 외과피의 혐오취를 저감시킬 수 있으며, 또한 혐오취가 저감된 은행 외과피 발효물을 제조할 수 있다.

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07-11-2017 дата публикации

청각 분해 활성을 갖는 신규한 바실러스 속 균주 및 이의 용도

Номер: KR0101784506B1
Принадлежит: 한국식품연구원

... 본 발명은 청각 분해 활성을 갖는 신규 바실러스 속 균주, 청각 분해 효소, 청각 분해용 조성물 및 청각 분해 방법을 제공한다. 본 발명에 따르면, 상기 청각 분해 효소는 청각을 직접적으로 분해 할 수 있고, 다양한 만난 올리고당을 분해할 수 있다. 청각 및 만난 올리고당의 분해에 본 발명의 균주 또는 청각 분해 효소를 이용하는 경우, 열수, 알칼리 또는 산처리가 요구되지 않고, 유기용매를 사용하지 않는바, 유용성분이 변질 또는 파괴되지 않고, 공정이 단순해지며, 환경오염을 시키지 않는 이점이 있다.

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21-01-2016 дата публикации

COMPOSITION COMPRISING LACTOBACILLUS PARACASEI AS ACTIVE INGREDIENT FOR PREVENTING, ALLEVIATING OR TREATING Th1-MEDIATED IMMUNE DISEASES OR Th2-MEDIATED IMMUNE DISEASES

Номер: KR1020160008060A
Принадлежит:

The present invention relates to a composition comprising Lactobacillus paracasei as an active ingredient for preventing, alleviating, or treating Th1-mediated immune diseases or Th2-mediated immune diseases. Lactobacillus paracasei of the present invention is capable of effectively controlling Th1-mediated immune diseases or Th2-mediated immune diseases, by activing control T cells, increasing generation of IL-10 which is anti-inflammatory cytokine, and inhibiting generation IL-12 which is immune-activating cytokine. Therefore, the composition can be used as an anti-allergic composition and an anti-inflammatory composition. COPYRIGHT KIPO 2016 ...

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