07-07-2023 дата публикации
Номер: CN116396499A
Принадлежит:
The invention discloses dopamine modified nano-composite hydrogel and a preparation method thereof. The preparation method comprises the following steps: (1) preparing modified nano-hydroxyapatite DA-HA of dopamine in an acid environment or modified nano-hydroxyapatite TDA-HA of dopamine in an alkaline environment; and (2) adding a methacrylate sulfobetaine aqueous solution, glyceryl polyether, an ethylene glycol dimethacrylate aqueous solution and an ammonium persulfate aqueous solution into the DA-coated HA or TDA-coated HA, stirring and mixing, then adding tetramethylethylenediamine, continuously stirring and mixing to obtain a reaction mixed solution, and standing to obtain the product. According to the preparation method disclosed by the invention, the dopamine modified nano-hydroxyapatite nanoparticles are used as a nano additive to be added into the zwitter-ion hydrogel, so that the interfacial compatibility between inorganic nanoparticles and organic matters is improved, the mechanical ...
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