24-01-2019 дата публикации
Номер: US20190024092A1
Принадлежит:
Provided are a microorganism having activity in reducing a concentration of a fluorine-containing compound in a sample, a recombinant microorganism including a gene derived from the microorganism, and a method of reducing the concentration of the fluorine-containing compound in the sample by using the microorganism or recombinant microorganism. 1Bacillus bombysepticus. A microorganism deposited with the Korean Collection for Type Culture (KCTC) under accession no. 13220BP and referred to as SF3 , which microorganism when contacted with a sample containing a fluorine-containing compound of Formula 1 or 2 reduces the concentration of the fluorine containing compound in the sample:{'br': None, 'sub': 1', '2', '3', '4, 'C(R)(R)(R)(R)\u2003\u2003'}{'br': None, 'sub': 5', '6', '7', '11', '12', '8', '9', '10, 'i': 'n', '(R)(R)(R)C—[C(R)(R)]-C(R)(R)(R)\u2003\u2003'}wherein, in Formulae 1 and 2,n is an integer from 0 to 10,{'sub': 1', '2', '3', '4', '1', '2', '3', '4, 'R, R, R, and Rare each independently fluorine (F), chlorine (Cl), bromine (Br), iodine (I), or hydrogen (H), wherein at least one selected from R, R, R, and Ris F, and'}{'sub': 5', '6', '7', '8', '9', '10', '11', '12', '5', '6', '7', '8', '9', '10', '11', '12, 'R, R, R, R, R, R, R, and Rare each independently F, Cl, Br, I, or H, wherein at least one selected from R, R, R, R, R, R, R, and Ris F, and'}{'sub': 11', '12, 'wherein, when n is equal or larger than 2, each Ris identical to or different from each other, and each Ris identical or different from each other.'}2. A recombinant microorganism comprising a genetic modification that increases the level of a polypeptide or a combination thereof , the polypeptide having a sequence identity of about 90% or more with respect to an amino acid sequence of SEQ ID NO: 1 , 2 , or 3.3. The recombinant microorganism of claim 2 , wherein the genetic modification is an increase in copy number of a gene encoding the polypeptide.4. The recombinant ...
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