АППЛИКАТОР И СИСТЕМА ДЛЯ ЭЛЕКТРОПОРАЦИИ

Группа изобретений относится к электропорации для повышения проницаемости клеток-мишеней и введения пациенту различных лечебных средств локализованного действия. Аппликатор для электропорации содержит: управляющую часть; вводимую трубку, соединенную с управляющей частью, причем вводимая трубка образует прокалывающий кончик; исполнительный механизм, находящийся в зацеплении с управляющей частью, причем по меньшей мере часть исполнительного механизма выполнена перемещаемой относительно управляющей части и вводимой трубки; электроды, включающие первый электрод, имеющий первый кончик, и второй электрод, имеющий второй кончик, при этом упомянутые электроды выполнены с возможностью перемещения между втянутым положением и выпущенным положением в ответ на приведение в действие исполнительным механизмом; и канал доставки лекарственного средства, выполненный с возможностью доставки субъекту эффективной дозы по меньшей мере одного лечебного препарата. При этом расстояние между первым кончиком первого ...

СИСТЕМА МОНИТОРИНГА ДЛЯ НЕПРЕРЫВНОЙ ДИАГНОСТИКИ МАТКИ

Изобретение относится к медицинской технике. Система (1000) мониторинга матки содержит внутриматочное вставочное устройство (100) для размещения в матке, модуль (200) размещения для разъёмного соединения с внутриматочным вставочным устройством, устройство (300) управления системой и дисплей (400). Выступающая часть внутриматочного вставочного устройства содержит датчик и выполнена с возможностью изгиба при соединении внутриматочного вставочного устройства с модулем размещения c обеспечением возможности прохождения выступающей части вставочного устройства вдоль влагалища, шейки матки и внутрь матки. Устройство управления системой функционально подключено для непрерывного приема сигналов от датчика и для преобразования их в данные, представляющие эти сигналы. Дисплей функционально подключен для отображения данных от устройства управления системой. Обеспечивается непрерывный мониторинг в течение продолжительных периодов времени с целью оптимизации процесса подготовки к оплодотворению, а также ...

РЕГУЛИРУЕМОЕ СЕНСОРНОЕ УСТРОЙСТВО ДЛЯ СЧИТЫВАНИЯ ФИЗИОЛОГИЧЕСКИХ ПАРАМЕТРОВ

Изобретение относится к сенсорному устройству. Сенсорное устройство содержит ремешок, включающий в себя по меньшей мере один датчик для измерения физиологического параметра на внутренней стороне запястья тела человека или животного и блок обработки сигналов для обработки выходных данных измерения, полученного от упомянутого по меньшей мере одного датчика. Упомянутый ремешок выполнен с возможностью обеспечения регулируемого прикрепления к упомянутому блоку обработки сигналов на обоих концах упомянутого ремешка. В результате обеспечивается точное расположение датчика на внутренней стороне запястья тела человека или животного. 2 н. и 9 з.п. ф-лы, 6 ил.

СИСТЕМА ДЛЯ ЗАЩИТЫ МЯГКИХ ТКАНЕЙ ОТ ВЕЩЕСТВА ДЛЯ ОТБЕЛИВАНИЯ ЗУБОВ

Устройство включает чистящую головку с проводящими волоконными щетинками, посредством которых подается потенциал для электрохимического активирования вещества для отбеливания зубов, например перекиси, вблизи зубов. Система (62) устройства на основе полного сопротивления или система (27) на основе оптического устройства обеспечивает информацию о том, находятся ли щетинки с проводящими волокнами вблизи поверхности зуба или вблизи десневой области. Первая из названных систем на основе полного сопротивления использует электрический сигнал через волокно для определения полного сопротивления цепи, включающей в себя зуб или поверхность десны, причем полное сопротивление будет различным в зависимости от участия в цепи зуба или десневой поверхности. Оптическая система генерирует пучок света, который направляется к поверхности полости рта через проводящее волокно, при этом цвет обратного света показывает, является ли поверхность зубной или десневой областью. Если определяется зуб, на этой щетинке ...

МЕДИЦИНСКАЯ СИСТЕМА

Изобретение относится к медицинской технике, а именно к медицинской системе для проникновения в анатомическую структуру пациента, которая содержит ткани с разными способностями проводить электрический ток. Система содержит корпус, первый и второй электроды, электрический генератор и устройство обработки. Корпус выполнен с возможностью проникновения в анатомическую структуру и имеет наружную поверхность. Первый электрод содержит первую контактную поверхность на наружной поверхности корпуса для вхождения в контакт с тканями анатомической структуры. Второй электрод содержит вторую контактную поверхность на наружной поверхности корпуса для вхождения в контакт с тканями анатомической структуры на расстоянии от первой контактной поверхности. Электрический генератор выполнен с возможностью подачи электрического тока между первой и второй контактными поверхностями. Устройство обработки выполнено с возможностью определять электрическую характеристику, отображающую способность ткани анатомической ...

СЛЕДЯЩЕЕ УСТРОЙСТВО ДЛЯ ТОКОВОЙ ЛОКАЛИЗАЦИИ

Изобретение относится к средствам определения положения объекта, введенного в живой организм. Способ отслеживания местоположения инструмента для исследования внутри тела пациента осуществляется устройством отслеживания и состоит в установке накладных электродов в гальваническом контакте с телом пациента, установке инструмента отображения, содержащего проводящий электрод инструмента отображения, во множестве областей в теле пациента, отслеживании инструмента отображения в разных положениях в каждой из областей, с использованием системы измерения местоположения, генерации для каждой области, соответствующей совокупности калибровочных токов между накладными электродами и проводящим электродом инструмента отображения в разных положениях, выведении посредством процессора для каждой области соответствующей зависимости между соответствующей совокупностью калибровочных токов и разными положениями, установке инструмента для исследования, содержащего проводящий электрод инструмента для исследования ...

Способ определения ударного объема сердца

Изобретение относится к области медицины, а именно к кардиологии, кардиохирургии, функциональной диагностике. Для определения ударного объема сердца выполняют наложение двух электродов на участки тела и регистрируют сопротивление между электродами. Ударный объем сердца определяют по исследуемой характеристике отношения сопротивлений регистрируемого к предельному с калибровочной функцией нормированного объема от сопротивления, компенсирующей неизвестное значение предельного сопротивления, выбранного произвольно. Значения предельного сопротивления и нормированного объема калибруют априори по нормированным мерам сопротивлений известных пациентов верхней и нижней границ диапазона и нормированным объемам от сопротивления с различной калибровкой для мужчин и женщин. Действительные значения предельного сопротивления и нормированного объема калибруют по границам диапазона согласно алгоритмам, по которым последовательно восстанавливают калибровочную функцию и действительную функцию, тождественную ...

УСТРОЙСТВО КОНТРОЛЯ ЗА ПРОХОЖДЕНИЕМ В АНАТОМИЧЕСКИЕ ЭЛЕМЕНТЫ

Изобретение относится к устройствам, обеспечивающим контроль за прохождением средства проникновения, в частности, в костные и другие структуры. Устройство содержит средство проникновения и, по меньшей мере, один прибор для измерения полного электрического сопротивления, который может быть соединен, по меньшей мере, с двумя электродами, по меньшей мере, один из которых находится на дистальном конце указанного средства проникновения, и, по меньшей мере, одно сигнальное устройство, выполненное с возможностью подачи сигнала предупреждения, модулированного пропорционально изменению полного сопротивления, в случае обнаружения изменения полного сопротивления прибором для измерения полного сопротивления. Изобретение раскрывает также инструмент для ручного и механического сверления и выполнение электронной карты для устройства в соответствии с настоящим изобретением. Устройство обеспечивает контроль за прохождением средства проникновения в режиме реального времени и тем самым позволяет избежать ...

СПОСОБ И ПРИБОР ДЛЯ ИНДУКТИВНОГО ИЗМЕРЕНИЯ БИОИМПЕДАНСА ТЕЛА ПОЛЬЗОВАТЕЛЯ

Изобретение относится к медицинской технике, а именно к способам и устройствам для индуктивного измерения биоимпеданса тела пользователя. Прибор для индуктивного измерения биоимпеданса включает в себя множество первых индукторов, выполненных в виде катушек возбуждения, предназначенных для наведения переменного магнитного поля в теле пользователя, множество вторых индукторов, выполненных в виде воспринимающих катушек, предназначенных для измерения вторичного магнитного поля в теле пользователя. Каждый из множества первых индукторов перекрывает по меньшей мере один из множества вторых индукторов с образованием матрицы областей измерения. Кровать, по первому варианту выполнения, включает в себя прибор для индуктивного измерения биоимпеданса, при этом первый и/или второй индуктор прибора включает в себя структурированный проводящий элемент на гибкой подложке, который выполнен из меди, а упомянутая гибкая подложка прикреплена к простыне. По второму варианту выполнения кровати первый и/или второй ...

СИСТЕМА, КОНТРОЛЛЕР И СПОСОБ ДЛЯ ОПРЕДЕЛЕНИЯ ЭЛЕКТРИЧЕСКОЙ ПРОВОДИМОСТИ ОБЪЕКТА

Изобретение, в общем, относится к системам контроля и, более конкретно, к способу определения электрической проводимости объекта или материала. Система содержит датчик, способный излучать электромагнитное поле при получении возбуждающего сигнала, причем при помещении в указанное электромагнитное поле объекта оно взаимодействует с этим объектом. Контур обработки сигнала, соединенный с датчиком и выполненный с возможностью: обеспечивать регулируемую емкость датчика для регулирования фазового угла тока, проходящего через датчик; производить измерение напряжения, соответствующего напряжению на датчике; производить измерение тока, соответствующего току, проходящему через датчик. Контроллер, соединенный с контуром обработки сигнала, выполненный с возможностью: расчета комплексной проводимости датчика на основании измерения напряжения и измерения тока и определения электрической проводимости объекта на основании рассчитанной комплексной проводимости датчика. Причем система выполнена с возможностью ...

ОБНАРУЖЕНИЕ КОНТАКТА И БЛИЗОСТИ МЕЖДУ АБЛЯЦИОННЫМИ ЭЛЕКТРОДАМИ ПОСРЕДСТВОМ ОПРЕДЕЛЕНИЯ ИЗМЕНЕНИЙ В МОРФОЛОГИИ НАПРЯЖЕНИЯ НЕАКТИВИРОВАННЫХ ЭЛЕКТРОДОВ

Группа изобретений относится к медицине, а именно к системе и способу обнаружения контакта и близости между абляционными электродами посредством определения изменений в морфологии напряжения неактивированных электродов. При этом вводят в тело пациента катетер, который содержит первый, второй и третий электроды, расположенные на дистальном конце катетера для обеспечения контакта с тканью внутри тела. Дистальный конец катетера выполнен с возможностью образования петли. Первый и второй электроды являются активированными, а третий электрод – неактивированным. Прикладывают с помощью генератора импульсов биполярные абляционные импульсы между первым и вторым активированными электродами для абляции ткани, находящейся в контакте с первым и вторым активированными электродами. Принимают с помощью контроллера сигнал, указывающий напряжение между третьим неактивированным электродом и опорным проводником во время приложения абляционных импульсов. Выдают с помощью контроллера уведомление в ответ на обнаружение ...

УСТРОЙСТВО И СПОСОБ ДЛЯ АНАЛИЗА ИМПЕДАНСА ТЕЛА ЧЕЛОВЕКА, НЕЧУВСТВИТЕЛЬНЫЕ К ВЫСОКОМУ КОНТАКТНОМУ ИМПЕДАНСУ И К ПАРАЗИТНЫМ ЭФФЕКТАМ

Группа изобретений относится к медицине, а именно к устройству и способу определения биоимпеданса. Первый и третий контактные электроды устройства предназначены для контакта с одной частью тела пользователя, второй и четвертый контактные электроды – для контакта с другой частью тела. Устройство содержит источник переменного тока, схему измерения тока, схему измерения напряжения, переключатель, содержащий четыре порта, и блок управления. Источник переменного тока и схема измерения тока имеют общую землю. При этом управляют переключателем для его перевода поочередно в первое и второе состояния для поочередного формирования, соответственно, первого и второго путей измерения тока. В первом состоянии переключателя ток протекает по телу пользователя через один из электродов, предназначенных для контакта с одной частью тела, к одному из электродов, предназначенных для контакта с другой частью тела, а во втором состоянии переключателя ток протекает в обратном направлении. В каждом из путей измерения ...

Устройство для проведения ранней диагностики несостоятельности анастомоза

Полезная модель относится к области диагностической медицинской техники, в частности к специальным диагностическим инструментам многоразового использования. Устройство для проведения ранней диагностики несостоятельности анастомоза, состоящее из двух электродов, термистора и диэлектрической прослойки для взаимоизоляции электродов, передает информацию о падении напряжения между электродами, а также падении напряжения на термисторе посредством проводов, заключенных в силиконовый герметичный гибкий провод к аппаратной части программно-аппаратного комплекса ранней диагностики несостоятельности анастомоза между полыми органами желудочно-кишечного тракта в целях автоматизированного анализа выборки результатов измерений температуры и проводимости. Преимуществами заявляемой полезной модели являются возможность внедрения датчика непосредственно в ходе операции, возможность постоянного контроля состояния области шва в послеоперационный период без необходимости осуществления дренирования, возможность ...

Устройство для измерения биопотенциалов в полости рта

Полезная модель относится к медицине, а именно к ортопедической стоматологии. Устройство для измерения биопотенциалов в полости рта содержит вольтметр, к измерительным выводам которого подключен кабель, разделенный на два провода, каждый из которых имеет разъемное соединение с соответствующим измерительным электродом, выполненным с возможностью размещения в полости рта пациента. Измерительные электроды выполнены с возможностью стерилизации. При этом один из измерительных электродов выполнен в виде щупа-зажима, а второй - в виде крючкообразного щупа.

СПОСОБ ОЦЕНКИ ПОВРЕЖДЕНИЯ МЫШЦ ДИАФРАГМЫ ТАЗА И ЗОНД И УСТРОЙСТВО ДЛЯ РЕАЛИЗАЦИИ СПОСОБА

Группа изобретений относится к медицине, а именно к устройствам и способам оценки травмы мышц диафрагмы таза. При этом вводят зонд в прямую кишку. Генерируют с использованием генератора электрические сигналы постоянной амплитуды и подводят их к мышцам диафрагмы таза при помощи подводящих электродов (ЕА1) и (ЕА2). Обнаруживают сигналы электрического напряжения от мышц диафрагмы таза с помощью измерительных электродов (EP1), (EP2)... (EP6). Анализируют сигналы электрического тока и напряжения для амплитудных значений и фазовых зависимостей их формы сигнала. При этом сигнал электрического тока и сигналы электрического напряжения от мышц тазового дна составляют сигналы, изменяющиеся по времени, частот в диапазоне от 2 до 200 кГц. Измерительный зонд для оценки повреждения мышц диафрагмы таза содержит цилиндрический основной корпус, два подводящих электрода и измерительные электроды. Измерительные электроды расположены на поверхности зонда. Каждый электрод имеет электрический контакт, проходящий ...

СПОСОБ ДИАГНОСТИКИ СТРЕССА В РАННЕМ НЕОНАТАЛЬНОМ ПЕРИОДЕ

Изобретение относится к медицине, а именно к неонатологии, может быть использовано в для диагностики стресса в раннем неонатальном периоде. Для этого проводят непрерывное мониторирование электродермальной активности в течение трех часов посредством регистрации сигналов кожной проводимости. Затем определяют показатель кумулятивного эффекта стресса DIS по показателям интенсивности стресс-стимулов за период мониторирования. Интенсивность стресс-стимулов определяют путем усреднения значений частот флуктуаций кожной проводимости за 1 минуту и выбора среди них значений, превышающих пограничное значение, равное 0,11 пик/с. Показатель кумулятивного эффекта стресса рассчитывают по разработанной формуле. Дополнительно определяют уровень лактата в капиллярной крови. Стресс диагностируют при значении указанного показателя DIS более 5,52 усл. ед. и уровне лактата в капиллярной крови более 5,2 ммоль/л. Изобретение обеспечивает возможность точно и объективно прогнозировать изменение состояния у данной ...

ИЗМЕРИТЕЛЬ СОСТОЯНИЯ БИООБЪЕКТА

Изобретение относится к области медицины, биологии, биофизики, биотехники и может быть использовано для регистрации и измерения полей биообъекта. Техническим результатом является повышение точности измерения состояния биообъекта при одновременном уменьшении времени оценки и увеличении достоверности полученной информации. Измеритель содержит N блоков для измерения, в состав которого входит датчик с органической пластиной, включенный в колебательный контур генератора, а кроме того, последовательно соединенные микропроцессорный контроллер и компьютер. Причем в каждый из блоков для измерения дополнительно включает варикап с конденсатором связи, резистор и формирователь с тремя состояниями на выходе, вход которого соединен с выходом генератора, причем датчик выполнен емкостным, его сигнальная пластина через конденсатор связи подключена к катоду варикапа, который через резистор связан с выходом регулирования микропроцессорного контроллера, а вторая пластина соединена с анодом варикапа. Выход ...

НОСИМОЕ УСТРОЙСТВО, СПОСОБ И СИСТЕМА ДЛЯ ИЗМЕРЕНИЯ ПАРАМЕТРОВ КРОВИ

Группа изобретений относится к медицине, в частности к носимому устройству, системе и способу определения по меньшей мере одного параметра крови пользователя. Производят извлечение наборов характеристик молекулярного строения крови с помощью по меньшей мере одного фотоплетизмографического (PPG) датчика и клеточного строения крови с помощью биоимпедансного (BIA) датчика. После чего формируют набор характеристик строения крови, определяющих состояние крови пользователя, и определяют значения по меньшей мере одного параметра крови пользователя, исходя из полученного набора характеристик молекулярного и клеточного строения крови и информации из заранее скомпилированной базы данных. Изобретение обеспечивает неинвазивный мгновенный или непрерывный контроль различных параметров крови, таких как, концентрация гемоглобина (cHb), общая масса гемоглобина (tHb), гематокрит (HCT), общий объем эритроцитов (tEV), объем плазмы (PV) в том числе при краевых значениях контролируемых параметров. 3 н. и 45 ...

УСТРОЙСТВО И СПОСОБ ДЛЯ ДИАГНОСТИКИ ВТОРИЧНОГО КАРИЕСА ЗУБОВ

... 1. Устройство для обнаружения вторичного кариеса, содержащее в своем корпусе (6) блок генерации тока, генерирующий ток, который имеет форму синусоидально изменяющегося сигнала, и имеет частоту, выбранную из диапазона частот от 200 Гц до 100 кГц, и амплитуду от 50 мВ до 5 В;блок предусилителей (4), имеющий фазочувствительные измерительные компоненты, чувствительные к выбранной частоте и к частотам, кратным выбранной частоте;микропроцессорный блок управления (5), подключенный к блоку генерации тока и к блоку предусилителей;по меньшей мере, один неподвижный электрод (2), подходящий для размещения на слизистой оболочке ротовой полости и подключенный к блоку измерения тока и к блоку предусилителей;по меньшей мере, один подвижный электрод, выполненный с возможностью установки на зубе (1) и подключенный к блоку измерения тока и к блоку предусилителей.2. Устройство по п. 1, отличающееся тем, что дополнительно содержит интерфейс (3), который может взаимодействовать с внешним устройством.3. Устройство ...

УСТРОЙСТВО И СПОСОБ ДЛЯ АНАЛИЗА ИМПЕДАНСА ТЕЛА ЧЕЛОВЕКА, НЕЧУВСТВИТЕЛЬНЫЕ К ВЫСОКОМУ КОНТАКТНОМУ ИМПЕДАНСУ И К ПАРАЗИТНЫМ ЭФФЕКТАМ

Группа изобретений относится к медицине, а именно к устройству и способу определения биоимпеданса. Первый и третий контактные электроды устройства предназначены для контакта с одной частью тела пользователя, второй и четвертый контактные электроды – для контакта с другой частью тела. Устройство содержит источник переменного тока, схему измерения тока, схему измерения напряжения, переключатель, содержащий четыре порта, и блок управления. Источник переменного тока и схема измерения тока имеют общую землю. При этом управляют переключателем для его перевода поочередно в первое и второе состояния для поочередного формирования, соответственно, первого и второго путей измерения тока. В первом состоянии переключателя ток протекает по телу пользователя через один из электродов, предназначенных для контакта с одной частью тела, к одному из электродов, предназначенных для контакта с другой частью тела, а во втором состоянии переключателя ток протекает в обратном направлении. В каждом из путей измерения ...

УСТРОЙСТВО (ВАРИАНТЫ) И СПОСОБ АВТОМАТИЧЕСКОГО МОНИТОРИНГА ПРИВЫЧЕК ПИТАНИЯ

КОМПОНОВКА ПЛАНАРНЫХ КАТУШЕК ДЛЯ УСТРОЙСТВА ИЗМЕРЕНИЯ МАГНИТОИНДУКТИВНОГО ИМПЕДАНСА

... 1. Компоновка (100, 200, 300, 400, 500) пленарных катушек для устройства (540) измерения магнитоиндуктивного импеданса, при этом компоновка (100, 200, 300, 400, 500) планарных катушек содержит:- катушку (102) возбуждения, сконфигурированную для формирования магнитного поля возбуждения в объекте, и- регистрирующую катушку (104, 204, 304, 404, 504а-с), сконфигурированную для регистрации ответного магнитного поля, сформированного в ответ на магнитное поле возбуждения, индуцирующее ток в объекте, причем катушка возбуждения и регистрирующая катушка расположены концентрично одна относительно другой вокруг общего центра; причем витки регистрирующей катушки расположены относительно катушки возбуждения так, чтобы токи, индуцируемые в ответ на магнитное поле возбуждения, имели противоположные знаки, но одинаковые амплитуды.2. Компоновка (100, 200, 300, 400, 500) планарных катушек по п. 1, в которой регистрирующая катушка (104, 204, 304, 404, 504а-с) проходит в угловом диапазоне (α) по окружности ...

СПОСОБ ОЦЕНКИ ЭФФЕКТИВНОСТИ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЙ СЕРДЕЧНО-СОСУДИСТОЙ СИСТЕМЫ И УСТРОЙСТВО ДЛЯ ЕГО ОСУЩЕСТВЛЕНИЯ

МЕДИЦИНСКАЯ СИСТЕМА

СПОСОБ И УСТРОЙСТВО ДЛЯ ОЦЕНКИ НАДЕЖНОСТИ РЕКОМЕНДАЦИИ ОТНОСИТЕЛЬНО РАЗРЯДА ПРИ СЕРДЕЧНО-ЛЕГОЧНОЙ РЕАНИМАЦИИ

СПОСОБ И СИСТЕМА ДЛЯ ПОЛУЧЕНИЯ И АНАЛИЗА ФИЗИОЛОГИЧЕСКИХ ДАННЫХ

УСТРОЙСТВО ДЛЯ НАКОПЛЕНИЯ И ВЫВЕДЕНИЯ ТЕКУЧЕЙ СРЕДЫ

... 1. Центробежный насос для использования с портативным устройством накопления текучей среды для накопления текучей среды, выделяемой субъектом, содержащий:по существу цилиндрическую камеру насоса, имеющую внутренний диаметр;впуск для текучей среды, находящийся в сообщении по текучей среде с камерой насоса;выпуск для текучей среды, находящийся в сообщении по текучей среде с камерой насоса; икрыльчатку, которая имеет наружный диаметр, и установлена с возможностью вращения на приводном валу внутри камеры насоса между впуском для текучей среды и выпуском для текучей среды, при этом приводной вал выполнен с возможностью вращения при помощи приводного средства, которое вращает крыльчатку при работе, и ускоряет поток текучей среды внутри камеры насоса через впуск для текучей среды и наружу через выпуск для текучей среды;при этом внутренний диаметр камеры насоса по существу равен или больше чем 1,40 наружного диаметра крыльчатки.2. Центробежный насос по п. 1, в котором внутренний диаметр камеры ...

УСТРОЙСТВО ИЗМЕРЕНИЯ ЖИРА ТЕЛА

... 1. Устройство измерения жира тела, содержащее: ! блок (100) присоединения к телу для измерения биоэлектрического импеданса, включающий в себя множество электродов (113), в присоединенном состоянии установленных в контакте с телом субъекта; ! участок (12) измерения импеданса для измерения биоэлектрического импеданса субъекта, используя множество электродов (113); и ! участок (13) вычисления массы жира тела для вычисления массы жира тела субъекта на основе биоэлектрического импеданса, измеренного участком (12) измерения импеданса; в котором ! блок (100) присоединения к телу для измерения биоэлектрического импеданса включает в себя опору (110) для электродов для поддержки множества электродов (113) и длинный ремень (140), который в присоединенном состоянии должен быть обернут вокруг тела субъекта, чтобы присоединить опору (110) для электродов к телу субъекта; ! ремень (140) включает в себя, по меньшей мере, в одной части растягивающуюся область (143), которая растягивается в направлении длины ...

СИСТЕМА И СПОСОБ ДЛЯ ПРОКАЛЫВАНИЯ ДЕРМАЛЬНОЙ ТКАНИ

... 1. Система для прокалывания дермальной ткани, содержащая прокалывающий кожу элемент, по меньшей мере, один электрический контакт, и измерительный прибор, выполненный с возможностью измерения электрической характеристики участка между прокалывающим кожу элементом и, по меньшей мере, одним электрическим контактом при использовании системы. 2. Система по п.1, в которой, по меньшей мере, один электрический контакт представляет собой электрический кожный контакт. 3. Система по п.1, в которой измерительный прибор выполнен с возможностью измерения электрической характеристики участка между прокалывающим кожу элементом и, по меньшей мере, одним электрическим контактом, характеризующей перфорирование дермальной ткани прокалывающим кожу элементом. 4. Система по п.1, в которой измерительный прибор выполнен с возможностью измерения электрической характеристики участка между прокалывающим кожу элементом и, по меньшей мере, одним электрическим контактом, характеризующей стабильность перфорирования дермальной ...

Vorrichtung zur Feststellung eines Perikardergusses

SYSTEM ZUR UNTERSUCHUNG VON GEWEBE NACH SEINEN DIELEKTRISCHEN EIGENSCHAFTEN

Bio-electrical resistance measuring device for e.g. head, has evaluation platform determining numerical value of internal parts of head and trunk using numerical values of internal parts of body parts

The device has a measurement device (40) including a central unit (42) and an evaluation platform (41). A modular data base (410) of the platform is connected with the central unit. The central unit has an input device (44) and an output device (45). The platform selects a modular group in the modular data base according to measurement of number of internal parts of body parts of the person and input of the personal data. The evaluation platform determines a numerical value of internal parts of head and trunk using the numerical values of the internal parts of the body parts. An independent claim is also included for a method for measuring bio-electrical resistance of human body parts.

SONDE FÜR DIE DIELEKTRISCHE UND OPTISCHE DIAGNOSTIK

Arrangement for interference-free time and position dependent impedance spectroscopy in hollow organs; has non-invasive measurement electrodes to fit shape of organ arranged on catheter

The arrangement has non-invasive measurement electrodes with small electrode polarisations, which fit the shape of the organ and are arranged on a hollow catheter with a larger outer diameter than the inner diameter of the organ or an elastic balloon catheter. The catheter is connected to a conventional retraction unit, which has a sensor for the retraction distance and any axial rotation. The catheter is connected to a circuit to generated pulses of a selected frequency between 0.1 kHz and 1 MHz and a measuring arrangement to determine the impedance spectrum from the pulse formations. The sensor at the retraction unit and the measurement arrangement connected to the catheter are connected to a processor circuit to determine the pulse formation as a function of the position of the catheter and its axial rotation.

TRAGBARES SENSORSYSTEM MIT MESSPFLASTER

Die Erfindung betrifft ein tragbares System (S) zur Messung und Überwachung physiologischer Parameter eines Menschen mittels Analyse einer seiner Körperflüssigkeiten, wobei das System (S) folgendes umfasst:- ein Verbrauchsteil (100) in Form eines Messpflasters zum Aufkleben auf die Haut (E), wobei das Messpflaster mit Sensorik (102) ausgestattet ist, die dazu eingerichtet ist, durch Körperflüssigkeitsanalyse Messwerte physiologischer Parameter zu liefern; und- eine am Körper tragbare und zum Dauereinsatz geeignete Ausleseeinheit (200), die dazu eingerichtet ist, die von der Sensorik (102) des Messpflasters gelieferten Messwerte auszulesen und zu überwachen. Die Ausleseeinheit (200) ist ferner dazu eingerichtet, über dem auf der Haut (E) aufgeklebten Messpflaster (100) getragen zu werden und in dieser Position die Messwerte auszulesen und zu überwachen.

Vorrichtung zur Beurteilung der Erholung des physischen Zustandes im Puerperium

Sensor for use with device for measuring dielectric characteristics of material, particularly biological material, has array of two coaxial single sensors, where each single probe has inner and outer conductors

The sensor has an array of two coaxial single sensors (2). Each single probe has an inner conductor (3), an outer conductor (4), and a dielectric (5) arranged between inner and outer conductors. An isolation layer (6) surrounds the outer conductor if necessary. The inner and outer conductors are made of stainless steel, particularly V2A steel alloy. The dielectric is made of thermoplastic, particularly polyhalogen olefin or Teflon(RTM: fluoropolymers). Independent claims are included for the following: (1) a device for measuring dielectric characteristics of a material; (2) a method for in-vitro or in-vivo determination of dielectric characteristics of a material, particularly of a biological material, by using a dielectric characteristics measuring device; and (3) a computer program for the execution and for controlling a dielectric characteristics measuring method.

VORRICHTUNG ZUR TRENDANALYSE EINES PHYSIOLOGISCHEN HERZPARAMETERS

Apparatus and methods for determining electrical conductivity of tissue

Electrode apparatus

Sensor

A device is arranged to couple electromagnetic radiation into or out of a biological material. The device comprises a first metamaterial comprising: a substrate component 101 having a thickness no greater than a first wavelength of the electromagnetic radiation; and a plurality of elements 103 supported by the substrate Component. Each element has a first dimension no greater than a first wavelength of the electromagnetic radiation and at least two of the elements are non-identical. The metamaterial may be used to resonate at a specific required wavelength. The device may be used as a sensor with a transmitter and receiver to couple wireless radiation via antennae. The senor may be worn on the body as a non-invasive glucose monitoring system for diabetes or for attachment to foodstuff containers. Low frequency (10-300 GHz), long wavelength (around 5mm in air) radiation may be used to allow penetration of human tissue.

A wearable body parameter recording means,computer,program and method for the same

Apparatus for measuring tissue sample electrical impedance

Biosensing textile and garment

The textile includes a distributed sensing system. The sensing system comprises a controller in communication with and controlling sensor electrodes on the textile. The sensor electrodes are formed of two-dimensional (2D) electrically conductive material, preferably graphene. Graphene forming the electrodes and electrical conductors is preferably printed or transferred onto the cloth. Alternatively, the conductor comprises conductive fibres or yarns forming the fabric. The preferred system includes a rechargeable battery, energy harvesting device, communicator operable over a 4G or 5G wireless cellular network. The textile is formed into a garment, especially shirt, t-shirt, blouse, dress, brassiere, shorts, trousers, vest, jacket, coat, glove, armband, underwear, headband, hat, cap, collar, waistband, stocking, sock, show, swimwear, wetsuit, drysuit or athletic clothing.

Vital Pad +

Apparatus and methods for determining electrical conductivity of tissue

Methods and apparatus for the detection of dental caries

Oral care device

An oral care device comprises a head portion and a handle portion. The head portion comprises at least one supporting arm and a base. The supporting arm extends from the base. A sensor is exposed from the supporting arm. The handle portion is configured to move relative to the head portion. The handle portion comprises a processor, wherein the processor is configured to receive signals from the sensor and analyze the signals received from the sensor.

Low power measurement of skin electrical properties

Examining objects using electric fields

PROBE FOR THE DIELECTRIC AND OPTICAL DIAGNOSTICS

DEVICE FOR POTENTIAL-SEPARATE CONVERTING OF A FIRST TENSION INTO A SECOND TENSION TO MEASURING IMPEDANCES AND ADMITTANZEN AT BIOLOGICAL FABRICS

SYSTEM FOR MONITORING OR TREATMENT OF ILLNESSES OF THE NERVOUS SYSTEM

PROCEDURES AND DEVICE FOR THE DETECTION OF KARDIOPULMONÄREN KOMORBIDITÄTEN

SYSTEM FOR MONITORING OR TREATMENT OF ILLNESSES OF THE NERVOUS SYSTEM

CATHETER FOR USE IN A SYSTEM FOR THE MONITORING OF SCHLEIMHAUTSCHÄDEN OF VISCOUS HOLLOW ORGANS

INTRALUMINALE ELECTRICAL FABRIC CHARACTERISATION AND CO-ORDINATED HF-ENERGY FOR THE SELECTIVE TREATMENT OF ATHEROM AND OTHER GOAL FABRICS

DEVICE FOR THE EVALUATION OF THE HÄMODYNAMI CONDITION OF A PERSON OF MEANS HEART LUNG INTERACTION

Mess- und Steuervorrichtung für ein Beatmungsgerät

Die Erfindung betrifft eine Mess- und Steuervorrichtung für ein Beatmungsgerät, insbesondere zur Steuerung der assistierten Beatmung, umfassend einen Sensorabschnitt zur Erfassung der Lungenfunktion, eine Auswerteeinheit, welche die vom Sensorabschnitt gelieferten Signale verarbeitet und gegebenenfalls über eine Ein- Ausgabevorrichtung verfügt, sowie eine Steuereinheit, welche aufgrund der von der Auswerteeinheit ermittelten Daten Steuerimpulse an ein Beatmungsgerät übermittelt. Der Sensorabschnitt umfasst mindestens in zwei transversalen Ebenen (10,12) des Bereichs der Lunge auf der Haut angeordnete Elektrodenpaare (6,7,8,9) für die Messung der Impedanz. Die Auswerteeinheit verarbeitet die Signale im Rahmen einer kontinuierlichen sektionalen Kreuz-Impedanzmessung und berechnet den jeweils aktuellen Ventilationsgrad der Lunge bzw. eines Lungenabschnitts und übermittelt über die Steuereinheit entsprechende Steuerimpulse, insbesondere über den Zeitpunkt eines Beatmungshubs, an ein Beatmungsgerät ...

PROCEDURE FOR THE MONITORING OF THE BLOOD SUGAR MIRROR

Method for recording and transmitting data between transmission unit and measurement module, involves transmitting data bidirectionally between measurement module and transmission unit

The method involves transmitting data bidirectionally between a measurement module (2) and a transmission unit (1) located within the near field of the measurement module by an antenna (5) that is arranged on the measurement module. The electromagnetic energy of the signal that is applied to the antenna is transformed and temporarily stored by a reception unit which is arranged downstream of the antenna. Another antenna (8) of the transmission unit is put in an inactive state during the time, the measured variables are sensed by the measurement module or the sensors (3). An independent claim is included for an arrangement for executing a data recording and transmitting method.

Method and apparatus for processing a pulmonary hypertension Impedanzkardiogrammen for judging the presence of a patient and impedance cardiac graph-with such a device

Die Erfindung betrifft ein Verfahren und eine Vorrichtung (1) zur Verarbeitung von Impedanzkardiogrammen (ICG) zur Beurteilung des Vorliegens einer pulmonalen Hypertonie (PH) einer Person (P), mit einer Einrichtung (2) zur Aufnahme und bzw. oder Speicherung des zeitlichen Verlaufs der Impedanz (Z(t)) der Person (P) als Impedanzkardiogramm (ICG), sowie einen Impedanzkardiographen (8) mit einer solchen Vorrichtung (1). Erfindungsgemäß ist eine Berechnungseinrichtung (3) zur Detektion des Minimums der ersten Ableitung der Impedanz (Z(t)) nach der Zeit ((dZ/dt)min) zu Beginn der Ejektionszeit während eines Herzschlages der Person (P) und zur Ermittlung einer Änderung der Impedanz (Z(t)) nach dem Minimum der Steigung ((dZ/dt)min) korrespondierenden Indikators (IPH) für das Vorliegen von pulmonaler Hypertonie (PH) vorgesehen.

Methods and apparatus for electrosurgical illumination

An illuminated energy device comprising a handle, an illumination element coupled to the handle and disposed continuously and circumferentially about an electrosurgical tip, the electrosurgical tip at a distal end of the handle. The illumination element is preferably adjustably coupled to the handle, and adjustment of the illumination element moves a distal end of the illumination element closer to or further away from a target such as tissue in a surgical field.

Wireless pressure ulcer alert dressing system

A wireless pressure ulcer alert dressing system for warning a patient or caregiver that soft tis-sue pressure or health condition has exceeded some predetermined level that over time would necessitate moving the patient to prevent or at least reduce a risk of soft tissue damage. The dressing assembly is adapted to be applied to or near a surface of the patient's body and generate electrical outputs corresponding to soft tissue pressure and other health characteristics sensed at the surface. The dressing assembly generates output signals based on the electrical outputs and correspond-ing to whether or not the soft tissue pressure has ex-ceeded a predetermined pressure level during the preselected time period. The dressing assembly in-cludes a pocket formed therein for removable, secured and protected insertion of a variety of different sensors such as multiple pressure sensors.

Grip strength device having detection function

A grip strength device having a detection function, comprising a grip strength assembly (1a, 1b, 1). The grip strength assembly (1a, 1b, 1) comprises a first support piece (11), a second support piece (12), and a rebound element (13); the first support piece (11) can be connected to the second support piece (12) by means of the rebound element (13); the grip strength assembly (1a, 1b, 1) is provided with a plurality of detection elements (2), a circuit element (3, 3b), a tension measurement element (6), and a power supply element (5, 5a); the circuit element (3, 3b) is connected to the power supply element (5, 5a) and the detection elements (2); the tension measurement element (6) can be in information connection with the circuit element (3, 3b). The grip strength device has the function of detecting both the magnitude of grip strength and in vivo muscle mass.

Cough detector

A device for detecting and counting coughing events is provided. In one embodiment a sensor for sensing and transducing low frequency and high frequency mechanical vibrations, sends signals to a coincidence detector that determines if high and low signals coincide. In another embodiment, ultrasonic energy is introduced to the trachea and if Doppler shift in frequency is detected, association is made to a coughing event. In another embodiment a change in the impedance of the neck is considered associated with coughing event if correlated over time with a specific mechanical frequency sensed.

Apparatus and method for radio frequency spectroscopy using spectral analysis

Devices, systems and methods for determining sizes of vessels

Method and device for monitoring breastfeeding

A method of monitoring amount of milk consumed by an infant being breastfed by a breast is disclosed. The method comprises: determining variations in electric capacitance of the breast during breastfeeding, and correlating the electric capacitance variations to an amount of milk consumed by the infant.

Apparatus, system and method for detection and delivery of a medicinal dose

An apparatus is disclosed as part of a system for tracking and confirming delivery of a medicinal dose to a user. The apparatus includes a detector. The detector is secured to and communicatively coupled to the user and is capable of detecting a current flow through the user's body. The current flow is produced when the user makes contact with the apparatus. The apparatus includes at least two contact areas connected to a power source where a circuit and, hence, a current path is completed through the user's body as the user makes contact with the apparatus. The current flow is detected by the detector, which is coupled to the user. Also disclosed is an apparatus for tracking and confirming delivery of a medicinal dose to a user where the apparatus includes an acoustic detector. Upon loading the dose into a chamber an acoustic vibration is generated. The vibration is detected and correlated with a current flow that is produced when the user makes contact with the apparatus. The combined ...

Method and system for monitoring hemodynamics

A system for monitoring hemodynamics of a subject is disclosed. The system comprises: a signal generating system configured for providing at least an output electric signal and transmitting the output signal to an organ of the subject. The system also comprises a demodulation system configured for receiving an input electrical signal sensed from the organ responsively to the output electric signal, and for modulating the input signal using the output signal to provide an in-phase component and a quadrature component of the input signal. The system also comprises a processing system configured for monitoring the hemodynamics based on the in-phase and the quadrature components.

Monitoring system

Impedance Analysis

A method fior use in analysing impedance measurements perforIcd on a subject. The method includes, in a processing system, determining a change in impedance, as a subject 5 undergoes call' extension or exercise and determining an indicator using the change impedance, the indicator being indicative oF an ejection volume to allow assessment of CMP function. 105' I103 104 2 5 A 1 2BA--, -2 3 117A] 115 117BA L Fig. 1 ...

Impedance mediated control of power delivery for electrosurgery

A method of controlling electrosurgical power delivery based on a comparison of sensed tissue impedance to various impedance threshold values is provided. Energy is delivered to tissue in a sealing cycle as a series of pulses. An initial pulse has a profile with a preset energy starting value that increases at a ramping rate to a preset end value. Sensed impedance data are monitored throughout each pulse and compared to each of an impedance threshold value for RF setpoint, an impedance threshold value for cumulative time, and an impedance threshold value for energy cutback. Based on sensed impedance during a pulse, the profile of a subsequent pulse can be modified. In the event of a high impedance event that reflects low tissue presence, energy may be cutback. A sealing cycle is stopped when a cumulative amount of time with an impedance value over the impedance cumulative time threshold value reaches a sealing cycle duration limit.

Electrode apparatus for measuring impedance within the human body, and apparatus using same for measuring impedance within the human body and performing treatment

The present invention relates to an electrode apparatus for measuring impedance within the human body, and to an apparatus using same for measuring impedance within the human body and performing treatment, which can automatically determine the precise location of a meridian within the human body, form a three-dimensional image of the location of the determined meridian, and enable acupuncture to be performed precisely at the position of the determined meridian. The electrode apparatus for measuring impedance within the human body comprises: a cylindrical housing member having a guide rod built into an open side thereof; a cylindrical electrode member to be pressed against the skin of the human body, and moved back and forth through the open side by means of the guide rod of the housing member; and a resilient member interposed between the cylindrical electrode member and the cylindrical housing member to resiliently move the cylindrical electrode member back and forth to/from the guide ...

Impedance measurement process

Apparatus for use in performing impedance measurements on a subject, the apparatus including a probe having a plurality of electrodes, the probe being configured to allow at least some of the electrodes to be in contact with at least part of the subject and a processing system for, determining at least one first impedance value, measured at a site using a first electrode configuration, determining at least one second impedance value, measured at the site using a second electrode configuration and determining an indicator indicative of the presence, absence or degree of an anomaly using the first and second impedance values.

METHOD AND APPARATUS FOR VERIFYING DATA MEASURED BY SEVERAL MEANS IN REAL-TIME

Measuring bioimpedance values and treating mental disorders

Analysis of eating habits

Miniature implantable illuminator for photodynamic therapy

Isolation of sensing circuit from pace generator

In a system for sensing electrical signals within a living body, and specifically for tracking location of an object in the body using impedance measurements, an 5 isolation circuit maintains isolation between the pacing and position sensing circuits, even while the heart is being paced. 15/04/15jm 18320 claims & abst.docx,13 V04 Lo Co C,4 N ce) C', co C14 L CIO Cf) cr) Cf) co CII) ...

Noninvasive body fluid stress sensing

Electrochemical impedance-based label-free and rapid biosensor for select bodily fluid biomolecule levels. Monoclonal antibodies to of biomolecule such as Cortisol were covalently attached to a 16-mercaptohexadecanoic acid functionalized gold working electrode using zero-length crosslinkers N-(3-dimethylaminopropyl)-N- ethylcarbodiimide and 10mM N-hydroxysulfosuccinimide. Cortisol was detected in phosphate buffered saline (simulated tear fluid) using a simple ferrocyanide reagent with a lower limit of detection of 18.73pM and less than 10% relative standard deviation.

Baroreceptor mapping system

A system including a mapping device, a stimulator, and a marker. The mapping device includes a plurality of electrodes to be situated on a baroreceptor region of a patient to map baroreceptors in the baroreceptor region. The stimulator is to stimulate selected electrodes of the plurality of electrodes to obtain physiological responses from the patient in response to stimulation of the selected electrodes. The marker is to be attached to the patient to mark a location of at least one of the selected electrodes based on an analysis of the physiological responses from the patient, where the marker is to maintain its location on the patient as the mapping device is removed from the patient.

Using radiofrequency (RF) transmission system to find opening in tissue wall

A method includes receiving, from a probe that includes electrodes and is positioned inside a cavity in an organ of a patient, (i) proximity signals indicative of 5 proximity of the electrodes to a wall of the cavity, and (ii) position signals indicative of positions of the electrodes within the cavity. Based on the proximity signals and the position signals, at least a portion of a volume of the cavity is represented by a sphere model 10 including multiple spheres. A direction is identified along which one or more spheres are larger than one or more surrounding spheres by at least a given factor. Based on the indicated direction, a location of an opening in the wall of the cavity is estimated and presented to a user. Logo ...

Handheld devices for use in medical procedures

The invention is a system and a handheld device for use in open or minimally invasive surgical procedures, such as a bone implant fixation procedure. The handheld device is configured to perform various functions during a bone implant fixation procedure, including performing at least one of: penetration of a bone to form a hole or opening for receipt of a screw; neuromonitoring, in cooperation with a neuromonitoring device, of the hole during, or post-, formation of the hole so as to sense any nearby nerves adjacent to the hole that may be in the path of a screw, or otherwise affected, when a screw is placed within the hole; neurostimulation, in cooperation with a neuromonitoring device, of nerves adjacent to the hole during, or post-, formation of the hole; and measuring of a depth of the hole and providing a digital measurement of the depth to assist the surgeon in selecting the appropriate length of screw.

Handheld devices for use in medical procedures

The invention is a system and a handheld device for use in open or minimally invasive surgical procedures, such as a bone implant fixation procedure. The handheld device is configured to perform various functions during a bone implant fixation procedure, including performing at least one of: penetration of a bone to form a hole or opening for receipt of a screw; neuromonitoring, in cooperation with a neuromonitoring device, of the hole during, or post-, formation of the hole so as to sense any nearby nerves adjacent to the hole that may be in the path of a screw, or otherwise affected, when a screw is placed within the hole; neurostimulation, in cooperation with a neuromonitoring device, of nerves adjacent to the hole during, or post-, formation of the hole; and measuring of a depth of the hole and providing a digital measurement of the depth to assist the surgeon in selecting the appropriate length of screw.

REMOTELY ADJUSTABLE INTERACTIVE BONE RESHAPING IMPLANT

Abstract According to some embodiments, systems and methods for reshaping bone are provided. The systems may include an implant body, an actuator coupled to the implant body, a sensor configured to detect a parameter indicative of a biological condition, a transceiver, and a controller. The transceiver may be configured to transmit data associated with the parameter to an external remote control and receive instructions from the external remote control. Finally, the controller is configured to move the actuator in response to the instructions from the external remote control, wherein the actuator adjusts the implant body. The methods may include measuring a parameter indicative of a biological condition; transmitting data associated with the parameter from the implantable device to an external remote control; transmitting instructions from the external remote control to the implantable device; and actuating the bone growth device in response to the instructions from the external remote ...

Acoustic switch and apparatus and methods for using acoustic switches within a body

Multiple frequency impedance measurement for physiological monitoring of the condition of a patient's body tissue

DETECTION OF SKIN IMPEDANCE

Apparatus and methods are provided for determining in near realtime the position of a probe placed within a living body. Electric currents are driven between one or more electrodes on the probe and electrodes placed on the body surface. The impedance between the probe and each of the body surface electrodes is measured, and three- dimensional position coordinates of the probe are determined based on the impedance measurements. Dynamic compensation is provided for changing impedance of the body surface and its interface with the electrodes, resulting from such causes as electrode peel- off and changes in moisture and temperature. The compensation improves the accuracy of, inter alia, medical procedures, such as mapping the heart or performing ablation to treat cardiac arrhythmias.

ELECTROPHYSIOLOGICAL APPROACHES TO ASSESS RESECTION AND TUMOR ABLATION MARGINS AND RESPONSES TO DRUG THERAPY

A method and system are provided for determining a condition of a selected region of tissue to facilitate the location of surgical resection margins. Electropotential and impedance are measured at one or more locations in an area of the body where tissue is to be removed. An agent may be introduced into the region of tissue to enhance electrophysiological characteristics of that tissue. The condition of the tissue is measured by electropotential and impedance profile. Differences in the profile are used to determine the borders between normal and abnormal tissue so as to facilitate what tissue to resect. Methods and apparatus are also disclosed to determine the efficacy of various therapies.

DATA COLLECTION DEVICE, SYSTEM, METHOD, AND COMPUTER PROGRAM PRODUCT FOR COLLECTING DATA RELATED TO THE DISPENSING OF CONTRAST MEDIA

... ²²²The present invention comprises devices, systems, methods, and computer ²program products for managing data related to the dispensing of contrast media ²as part of a medical procedure. The device and system provide a controller ²that is capable of communicating with a dispensing device so as to extract, ²arrange, process, and present a data set (e.g., a usage data set) from the ²dispensing device to a user such that the user may selectively monitor ²statistics related to the administration of contrast media, saline, or other ²consumables used during one or more dispensing operations. The method and ²computer program product for managing data related to the dispensing of ²contrast media may further allow for extraction, arrangement, processing, and ²presentation of the data set via the controller, via a user, interface that is ²operably engaged with the dispensing device and/or via a computer network that ²may be in communication with the dispensing device.² ...

DISTRIBUTED EXTERNAL AND INTERNAL WIRELESS SENSOR SYSTEMS FOR CHARACTERIZATION OF SURFACE AND SUBSURFACE BIOMEDICAL STRUCTURE AND CONDITION

Systems and methods are disclosed that use wireless coupling of energy for operation of both external and internal devices, including external sensor arrays and implantable devices. The signals conveyed may be electronic, optical, acoustic, biomechanical, and others to provide in situ sensing and monitoring of internal anatomies and implants using a wireless, biocompatible electromagnetic powered sensor systems.

MEDICAL DEVICE SYSTEM

The invention provides a medical device system comprising at least two technologies wherein at least one technology is based on bio-impedance measuring and/or at least one technology is based on spectrophotometry measurements wherein software cross analyses the results to assess the homeostasis of an individual. The technologies measure a variety of parameters. In one embodiment the bioimpedance measuring equipment measures in bipolar mode and in tetrapolar mode and the spectophotmeter measuring equipment comprises a pulse oximeter. The system and homeostasis score can be used to determine and monitor therapy for a patient.

METHOD OF DETERMINING DEPTH OF COMPRESSIONS DURING CARDIO-PULMONARY RESUSCITATION

A method of processing a raw acceleration signal, measured by an accelerometer-based compression monitor, to produce an accurate and precise estimated actual depth of chest compressions. The raw acceleration signal is filtered during integration and then a moving average of past starting points estimates the actual current starting point. An estimated actual peak of the compression is then determined in a similar fashion. The estimated actual starting point is subtracted from the estimated actual peak to calculate the estimated actual depth of chest compressions. In addition, one or more reference sensors (such as an ECG noise sensor) may be used to help establish the starting points of compressions. The reference sensors may be used, either alone or in combination with other signal processing techniques, to enhance the accuracy and precision of the estimated actual depth of compression.

SINGLE RADIO-TRANSPARENT CONNECTOR FOR MULTI-FUNCTIONAL REFERENCE PATCH

A patch and sensor assembly has a magnetic-based biosensor is housed in a reusable portion that connects to the mapping and localization system via biosensor wires, and a disposable portion provides an electrode layer through which impedance-based signals are transmitted to the mapping and localization system via ACL wires, wherein the biosensor wires and the ACL wires extend through a single cable exiting the reusable portion. In one embodiment, the disposable portion includes an adhesive layer for adhering the electrode layer to a patient's body where the electrode layer is disposed on the adhesive hydrogel layer. The disposable portion also includes a foam layer disposed on the electrode layer, and an engagement element adapted to detachably receive at least a portion of a housing of the resuable portion. In one embodiment, the reusable portion includes a housing defining a sealed interior volume in which a magnetic-based biosensor is provided with biosensor wires that exit the reusable ...

Biological information measurement device, biological information measurement method, and body composition measurement device

To accurately acquire body composition information using data acquired by another device. Thus, there is provided a body composition monitor with scale including a communication unit for allowing input of biological component information (cross-sectional area, site length, subcutaneous fat percentage, visceral fat percentage, etc.) of a living body measured with another device such as an MRI, where step of calculating the body composition of the living body based on the biological component information, an impedance detected by an impedance detection unit, and a weight measured by a load detection unit is executed.

Электрораздражитель для исследования суправитальных реакций

Полезная модель относится к медицине и может быть применена в судебно-медицинской практике в части определения времени наступления смерти по суправитальным реакциям. Техническая проблема заявленной полезной модели заключается в повышении надежности устройства для определения давности наступления смерти по суправитальным реакциям организма. Технический результат заключается в обеспечении возможности точного определения давности наступления смерти по суправитальным реакциям организма. Указанный технический результат достигается в электрораздражителе для исследования суправитальных реакций, содержащем корпус с установленным в нем электронным блоком, выполненным с возможностью вырабатывать электрические импульсы, а также игольчатыми электродами, дополнительно содержит встроенный аккумулятор, игольчатые электроды соединены с корпусом посредством кабеля, с возможностью его отсоединения от корпуса, на передней панели корпуса выполнены: кнопка включения электрического импульса, световой индикатор состояния аккумулятора с плавно изменяющимися цветовыми показателями, переключатель тока, при этом задняя панель электрораздражителя содержит разъем для подключения зарядного устройства, световой индикатор режима зарядки и выключатель питания прибора, а электронный блок, преобразуя постоянный ток в переменный, выполнен с возможностью работы в двух режимах, различающихся между собой по мощности вырабатываемых электрических импульсов для возможности исследования реакций организмов в зависимости от степени развития мышечной ткани исследуемого объекта. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 208 292 U1 (51) МПК G01N 33/48 (2006.01) A61B 5/053 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ (52) СПК G01N 33/48 (2021.08); A61B 5/0538 (2021.08) (21)(22) Заявка: 2021125386, 27.08.2021 (24) Дата начала отсчета срока действия патента: Дата регистрации: 13.12.2021 R U 2 0 8 2 9 2 U 1 Адрес для переписки: 107045, Москва, Сретенский б-р, 5, ...

Pulse detection apparatus, software, and methods using patient physiological signals

The presence of a cardiac pulse in a patient is determined by evaluating physiological signals in the patient. In one embodiment, a medical device evaluates two or more different physiological signals, such as phonocardiogram (PCG) signals, electrocardiogram (ECG) signals, patient impedance signals, piezoelectric signals, and accelerometer signals for features indicative of the presence of a cardiac pulse. Using these features, the medical device determines whether a cardiac pulse is present in the patient. The medical device may also be configured to report whether the patient is in a VF, VT, asystole, or PEA condition, in addition to being in a pulseless condition, and prompt different therapies, such as chest compressions, rescue breathing, defibrillation, and PEA-specific electrotherapy, depending on the analysis of the physiological signals. Auto-capture of a cardiac pulse using pacing stimuli is further provided.

Apnea type determining apparatus and method

An apnea classification system provides for apnea monitoring and differentiation based on several sleep apnea related parameters for diagnostic and therapeutic purposes. Monitoring of such sleep apnea related parameters allows the apnea classification system to differentiate among the different types of apnea and hypopnea and to identify an occurrence of periodic respiration. This information may then be used to determine the best method of therapy, or adjust current therapy parameters to more effectively treat a subject.

Seizure detection using coordinate data

A seizure detection device includes a coordinate data interface configured to receive coordinate data for a human, a memory to store coordinate data for a defined location of the human, and a seizure detector configured to identify a seizure event responsive to the coordinate data.

Medical device and methods of monitoring a patient with renal dysfunction

Embodiments relate to a method of monitoring physiological parameters of a patient with renal dysfunction. The method includes electrically connecting one or more medical device electrodes with a measurement site of a patient, generating one or more first stimulation signals sufficient to provide input physiological parameters specific to the patient, measuring one or more first bioimpedance values from the generated signals, analyzing at least one of the input physiological parameters within the one or more first bioimpedance values and generating a personalized dialysis program. The systems and methods can further provide essentially real-time data of patient undergoing treatment and control of treatment to a patient.

Devices and methods for respiratory variation monitoring by measurement of respiratory volumes, motion and variability

This invention is directed to devices and methods for assessing a patient. The devices have at least one impedance measuring element functionally connected to a programmable element, programmed to analyze an impedance measurement, and to provide an assessment of at least one respiratory parameter of the patient. Preferably the device includes electronics which aid in calibration, signal acquisition, conditioning, and filtering.

Cardiac monitoring system

A method of analysing cardiac functions in a subject using a processing system is described. The method may include applying one or more electrical signals having a plurality of frequencies to the subject and detecting a response to the applied one or more signals from the subject. A characteristic frequency can then be determined from the applied and received signals, and at least one component of the impedance (e.g., reactance, phase shift) can be measured at the characteristic frequency. The impedance or a component of impedance at a characteristic frequency can be determined for a number of sequential time instances. A new characteristic frequency may be determined within a cardiac cycle or the same characteristic frequency may be used throughout the cardiac cycle during which instantaneous values of impedance are determined. These values may be used to determine an indicia of cardiac function.

Methods and systems for determining vascular bodily lumen information and guiding medical devices

Methods and systems for determining information about a vascular bodily lumen are described. An exemplary method includes generating an electrical signal, delivering the electrical signal to a plurality of excitation elements in the vicinity of the vascular bodily lumen, measuring a responsive electrical signal from a plurality of sensing elements in response to the delivered electrical signal, and determining a lumen dimension. Specific embodiments include generating a multiple frequency electrical signal. Another embodiment includes measuring a plurality of responsive signals at a plurality of frequencies. Still other embodiments include using spatial diversity of the excitation elements. Yet other embodiments use method for calibration and de-embedding of such measurements to determine the lumen dimensions. Diagnostic devices incorporating the method are also disclosed, including guide wires, catheters and implants. The methods and systems described herein are advantageous as they do not include injecting a second fluid for the measurements.

Diagnosis apparatus

A diagnosis apparatus encompasses a probe array ( 1, 2 ) made of material having electromagnetic characteristic identical to the electromagnetic characteristic of a target object, the probe array ( 1, 2 ) embraces a receptacle 1 having a semispherical inner wall surface, and a plurality of antennas 2, arranged along the inner wall surface, the plurality of antennas 2 carry out electrical measurement of a target region in the target object, a fixing mechanism configured to cover whole of the target region with the probe array ( 1, 2 ), bringing skin of the target region into close contact with the inner wall surface, so as to fix a relative position between the target region and the probe array ( 1, 2 ), and a measuring, controlling and analyzing mechanism configured to control the plurality of antennas 2, to execute the electrical measurement, and to analyze a data based on the electrical measurement so as to detect an abnormal cell in the target region. The diagnosis apparatus has a high contrast and a high resolution and does not suffer from any X-ray exposure and is low in diagnosis cost and safe, sure, comfortable and high in speed and high in reliability.

Reactance changes to identify and evaluate cryo ablation lesions

A method of assessing lesion quality of an ablated tissue region comprising ablating at least a portion of the tissue region. The reactance of the ablated tissue region is measured. The lesion quality of the ablated tissue region is determined based on the measured reactance.

System and Method for Pain Reduction

Systems and methods for treating pain are described. Systems and methods for treating pain using video games, tilt tables and bio-sensors are described wherein the level of the video game is controlled by a computer based on the feedback from a patient. Corresponding systems are also disclosed.

Tracking system using field mapping

In some aspects, a method includes (i) securing multiple sets of current injecting electrodes to an organ in a patient's body, (ii) causing current to flow among the multiple sets of current injecting electrodes to generate a field in the organ, (iii) in response to current flow caused by the multiple sets of current injecting electrodes, measuring the field at each of one or more additional electrodes, (iv) determining expected signal measurements of the field inside the organ using a pre-determined model of the field, and (v) determining a position of each of the one or more additional electrodes in the organ based on the measurements made by the additional electrodes and the determined expected signal measurements of the field.

Handheld excitation terminal and emf emitter providing dynamic optimization of emission and therapeutic effect and remote therapeutic system

A cell excitation terminal and a therapeutic system using customized electromagnetic (EM) waves varying dynamically with time for excitation include one or more EM wave generators, each of the EM wave generators is connected to a central processing unit (CPU), and the CPU controls, according to a signal detected by a human body status detection device, the EM wave generator to send EM waves corresponding to a detected status or subject patient. The therapeutic system can perform remote management. A remote server optimizes and updates therapeutic waveforms of a patient constantly according to a therapeutic effect of the patient, thereby improving the therapeutic effect constantly.

Method and system to estimate impedance of a pseudo sensing vector

An implantable medical device (IMD) is provided comprising inputs configured to be coupled to leads having electrodes thereon, wherein combinations of the electrodes are associated with respective active sensing vector. The IMD further comprises an impedance measurement module to collect multiple measured impedances between corresponding combinations of the electrodes. The IMD further includes an impedance derivation module to calculate a derived impedance for at least one pseudo sensing vector based on the measured impedances, wherein the pseudo sensing vector extends to or from at least one pseudo sensing site.

Sensor for Detecting Cancerous Tissue and Method of Manufacturing the Same

Disclosed herein are a sensor for detecting cancerous tissue, a method of manufacturing the same, and a method of monitoring the presence and status of cancerous tissue in real time. The sensor for detecting cancerous tissue includes a board, one or more pairs of needle electrodes, and an output unit. The needle electrodes are formed on the board, and obtain electrical signals from tissue. The output unit outputs the electrical signals, obtained from the electrodes, to the outside.

Tuned rf energy for selective treatment of atheroma and other target tissues and/or structures

A catheter and catheter system can use energy tailored for remodeling and/or removal of target material along a body lumen, often of atherosclerotic material of a blood vessel of a patient. An elongate flexible catheter body with a radially expandable structure may have a plurality of electrodes or other electrosurgical energy delivery surfaces to radially engage atherosclerotic material when the structure expands. An atherosclerotic material detector system may measure and/or characterize the atherosclerotic material and its location, optionally using impedance monitoring.

Implanted device data to guide ablation therapy

A medical device system and associated method for guiding ablation therapy sense cardiac signals using implantable electrodes and detect spontaneous cardiac events from the sensed cardiac signals. Pacing pulses are delivered and a return cycle length is measured in response to the plurality of pacing pulses. The spontaneous cardiac event is clustered with a previously detected cardiac event in response to the measured return cycle length, and a targeted ablation site is estimated in response to the measured return cycle length. A transit time interval, corresponding to a distance traversed by a depolarization associated with a last one of the plurality of pacing pulses when a reset condition occurs, is computed using the return cycle length, and the ablation site is estimated in response to the computed transit time interval.

Diagnostic Classifications of Pulse Signal Waveform Data

Diagnostic classifications of pulse signal waveform data is provided. In one example, diagnosis or prediction of a disease may be performed by analyzing pulse signal waveform data, and comparing aspects of the pulse signal waveform data with a morphology pattern that has been found to indicate a subject is suffering from a specific disease. A pulse signal can be captured via wrist electrodes using bio-electric sensors based on an impedance plethysmographic principle, for example, and processed using feature extraction for diagnosis and assessment of the subject's proneness to a disease. Analysis of the pulse signal and pulse morphology patterns provides an in-vitro, non-invasive, and low-cost method for diagnosing diseases.

Implantable medical device and method for multisite measurement of intracardiac impedance

The present invention generally relates to an implantable medical device and method for detecting and monitoring cardiac status of a patient using simultaneous multisite measurements of the intracardiac impedance and in particular to ischemia detection using the simultaneous multisite measurements. The device comprises an impedance measuring unit being connectable to a plurality of electrode configurations including a current generating device adapted to generate a current and apply the current between two electrodes of a current injecting electrode configuration of the electrode configurations and a voltage sensing device including a plurality of voltage sensing circuits arranged in parallel. Each voltage sensing circuit being connectable to a specific voltage sensing electrode configuration of the electrode configurations and being arranged to sense a voltage over the voltage sensing electrode configuration resulting from the applied current, wherein the voltage sensing circuits are capable of sensing the resulting voltages simultaneously. The device further comprises an impedance calculating module adapted to calculate a plurality of impedance values, each impedance value being based on the applied current and a resulting voltage.

Devices and methods for monitoring cerebral hemodynamic characteristics

Devices, and methods for receiving and comparing bioimpedance signals are disclosed. In one aspect, the devices and methods may include receiving bioimpedance signals indicative of hemodynamic characteristics within a subject's brain. Bioimpedance signals may be compared, and the comparison used to provide information for diagnosing changes in arterial occlusion. Bioimpedance signals may be associated with left and right sides of a subject's brain. Signature features within the bioimpedance signals may be detected and used to determine differences in the bioimpedance signals.

Method and Apparatus for Measuring Blood Volume

In one aspect, a conductance catheter is provided for measuring the volume of a fluid. The conductance catheter comprises a series of electrodes and a circuit to compensate for variations in sensitivity of the electrodes in the catheter. In another aspect, a resistivity sensor is provided for determining the resistivity of a fluid. The sensor comprises a series of electrodes spaced such that the total distance between endmost electrodes does not exceed the diameter of the catheter deploying the sensor.

Systems and Methods for Activating and Controlling Impedance-Based Detection Systems of Implantable Medical Devices

Techniques are provided for use with implantable medical devices for addressing encapsulation effects, particularly in the detection of cardiac decompensation events such as heart failure (HF) or cardiogenic pulmonary edema (PE.) In one example, during an acute interval following device implant, cardiac decompensation is detected using heart rate variability (HRV), ventricular evoked response (ER) or various other non-impedance-based parameters that are insensitive to component encapsulation effects. During the subsequent chronic interval, decompensation is detected using intracardiac or transthoracic impedance signals. In another example, the degree of maturation of encapsulation of implanted components is assessed using impedance frequency-response measurements or based on the frequency bandwidth of heart sounds or other physiological signals. In this manner, impedance-based HF/PE detection systems can be activated as soon as component encapsulation has matured, without necessarily waiting until completion of a preset post-implant maturation interval, often set to forty-five days or more.

Biometric healthcare data system

A biometric healthcare data system has biometric data collection stations and a network management system. Each station has several biometric data measurement devices including a bioelectrical impedance analysis system. Each station has a gateway that connects to the devices and that connects the station through the internet to the network management system. The network management system has a communications manager that tracks the stations, a content manager that provides content to the stations and a data manager that retrieves and stores data from the data collection stations.

Pulse detection apparatus, software, and methods using patient physiological signals

The presence of a cardiac pulse in a patient is determined by evaluating physiological signals in the patient. In one embodiment, a medical device evaluates two or more different physiological signals, such as phonocardiogram (PCG) signals, electrocardiogram (ECG) signals, patient impedance signals, piezoelectric signals, and accelerometer signals for features indicative of the presence of a cardiac pulse. Using these features, the medical device determines whether a cardiac pulse is present in the patient. The medical device may also be configured to report whether the patient is in a VF, VT, asystole, or PEA condition, in addition to being in a pulseless condition, and prompt different therapies, such as chest compressions, rescue breathing, defibrillation, and PEA-specific electrotherapy, depending on the analysis of the physiological signals. Auto-capture of a cardiac pulse using pacing stimuli is further provided.

Electrode impedance spectroscopy

Aspects of the present invention are generally directed to impedance spectroscopy in an active implantable medical device (AIMD) comprising a component with one or more electrodes. In an embodiment, the AIMD applies a signal at a plurality of frequencies using one or more of the electrodes. Measurements are then obtained for the applied signal to determine impedance(s) at the applied frequencies of the tissue in which the electrodes are located.

Methods and systems for indicating behavior in a population cohort

Avatars, methods, apparatuses, computer program products, devices and systems are described that carry out identifying a member of a population cohort; and indicating at least one behavior in the member of the population cohort based on an association between the population cohort and at least one cohort-linked avatar.

Method and system for detecting electrophysiological changes in pre-cancerous and cancerous breast tissue and epithelium

A method and system are provided for determining a condition of a selected region of epithelial and stromal tissue in the human breast. A plurality of measuring electrodes are used to measure the tissue and transepithelial electropotential of breast tissue. Surface electropotential and impedance are also measured at one or more locations. An agent may be introduced into the region of tissue to enhance electrophysiological characteristics. The condition of the tissue is determined based on the electropotential and impedance profile at different depths of the epithelium, stroma, tissue, or organ, together with an estimate of the functional changes in the epithelium due to altered ion transport and electrophysiological properties of the tissue. Devices for practicing the disclosed methods are also provided.

Health monitoring appliance

A heart monitoring system for a patient includes one or more wireless nodes forming a wireless network; a wearable appliance having a wireless transceiver to communicate with the one or more wireless nodes; and an analyzer to determine vital signs, the analyzer coupled to the wireless transceiver to receive patient data over the wireless network.

Visceral fat measurement device

A visceral fat measurement device includes a current-applying electrode pair including a first current-applying electrode and a second current-applying electrode, and a voltage measurement electrode pair including a first voltage measurement electrode and a second voltage measurement electrode. The current-applying electrode pair is arranged on a projected line obtained by projecting the body trunk axis of a measured body to the body surface of an abdominal part of the measured body. The first and second current-applying electrodes are separated from each other at a predetermined interval determined so that a current path connecting the first current-applying electrode, visceral fat, and the second current-applying electrode is formed. The voltage measurement electrode pair is arranged between the first and second current-applying electrodes in a direction along the body trunk axis of the measured body.

Method and device for measuring electrical impedance of biologic tissues

A device for measuring an electrical impedance of biologic tissue may include electrodes configured to contact the biologic tissue and generate a differential voltage thereon. The device may include a first circuit coupled to the electrodes and configured to force an oscillating input signal therethrough, and a differential amplitude modulation (AM) demodulator coupled to the plurality of electrodes. The differential AM demodulator may be configured to demodulate the differential voltage, and generate a base-band signal representative of the demodulated differential voltage. The device may further include an output circuit downstream from the differential AM demodulator and may be configured to generate an output signal representative of the electrical impedance as a function of the base-band signal.

Contact sensor and sheath exit sensor

A system and method is provided that allows for determining the local impedance of one or more electrodes of an electrode catheter. Such local impedance may be utilized to identify the relative position of an electrode catheter to a sheath of a guiding introducer. In another arrangement, local impedance of a catheter electrode can be utilized to calibrate a catheter electrode to provide improved contact sensing.

Personal emergency response (per) system

Systems and methods for identifying an activity of an object includes identifying each elemental motion of a sequence of elemental motions of a device attached to the object; and identifying the activity of the object, comprising matching the sequence of identified elemental motions of the device with a library of stored sequences of elemental motions, wherein each stored sequence of elemental motions corresponds with an activity.

Devices and methods for treatment of heart failure and associated conditions

Devices and methods of use for identification, treatment, and/or management of heart failure and/or associated conditions. Methods may include providing a baroreflex therapy system including a blood pressure sensor and a heart rate sensor, providing an implantable measurement device proximate a blood vessel of a patient, the implantable measurement device including an electrode, providing a control system coupled to the baroreflex therapy system and the implantable measurement device, the control system programmed to automatically determine an impedance of the blood vessel with the implantable measurement device over a time period of at least one cardiac cycle, determine arterial stiffness of the blood vessel based on the impedance, determine blood pressure and heart rate, and activate, deactivate or otherwise modulate the baroreflex therapy system to deliver a baroreflex therapy based on the blood pressure, heart rate and arterial stiffness.

Systematic distillation of status data relating to regimen compliance

Configuration technologies for cost-effectively monitoring indicia of regimen compliance or noncompliance in response to one or more indications of symptoms or actions or other data on data-bearing media or in wireless transmissions, such as implementing techniques for providing or preventing access or otherwise acting on or communicating incremental or definitive indicia of compliance or noncompliance.

Device and method for accessing and treating ducts of mammary glands

This application relates to a device for the local delivery of a substance to a mammary duct by ductal cannulation via an orifice on a nipple, wherein the substance may any substance or combinations of substances, such as for example, compositions capable of forming a solid or semisolid gel within the ducts, a marker, and/or an active agent which is preferably effective in treating and/or preventing breast cancer. More particularly, a device is disclosed comprising a probe for locating the orifice on the nipple, wherein the device is further configured to cannulate the duct and allow local delivery of a substance(s).

Arrhythmia Classification

An implantable medical device ( 100 ) is configured for generating a cardiogenic impedance signal representative of the cardiogenic impedance of at least a portion of a heart ( 10 ) of a subject ( 20 ) during multiple cardiac cycles. A transform processor ( 132 ) generates a spectrum signal by applying a time-to-frequency transform to the cardiogenic impedance signal. The spectrum signal is processed by a distribution processor ( 133 ) configured to calculate a distribution parameter indicative of a distribution in at least a portion of the spectrum signal. The calculated distribution parameter is of high diagnostic value and is employed by an arrhythmia classifier ( 134 ) in order to classify a detected arrhythmia of the heart ( 10 ), such as discriminate between hemodynamically stable or unstable arrhythmias and/or supraventricular or ventricular tachycardia.

Method and System for Determining Audience Response to a Sensory Stimulus

The present invention is directed to a method and system for measuring the biologically based responses of an audience to a presentation that provides sensory stimulating experience and determining a measure of the level and pattern of engagement of that audience to the presentation. In particular, the invention is directed to a method and system for measuring one or more biologically based responses of one or more persons being exposed to the presentation in order to determine the moment-to-moment pattern and overall level of engagement. Further, the invention can be used to determine whether the presentation or the content in the presentation is more effective in a population relative to other presentations (or content) and other populations and to help identify elements of the presentation that contribute to the high level of engagement and the effectiveness and success of the presentation for that population.

Cystic fibrosis diagnostic device and method

A method for detecting cystic fibrosis is disclosed, which is performed in a system comprising an anode and a cathode placed on different regions of the patient body, and an adjustable DC source, which is controlled in order to feed the anode with a DC current. The method includes applying DC voltage pulses of varying voltage values to the anode for given durations allowing the stabilization of electrochemical phenomena in the body in the vicinity of the electrodes, collecting data representative of the current between the electrodes, and of the potentials of the electrodes, for the different DC voltages, and from the data, computing data representative of the electrochemical skin conductance of the patient, and reconciling the latter data with reference data obtained in the same conditions on patients suffering or not from cystic fibrosis, and identifying the patient as suffering or not from cystic fibrosis.

Systems and methods for assessing heart failure and controlling cardiac resynchronization therapy using hybrid impedance measurement configurations

Techniques are provided for use with an implantable medical device for detecting and assessing heart failure and for controlling cardiac resynchronization therapy (CRT) based on impedance signals obtained using hybrid impedance configurations. The hybrid configurations exploit right atrial (RA)-based impedance measurement vectors and/or left ventricular (LV)-based impedance measurement vectors. In one example, current is injected between the device case and a ring electrode in the right ventricle (RV) or RA. RA-based impedance values are measured along vectors between the device case and an RA electrode. LV-based impedance values are measured along vectors between the device case and one or more electrodes of the LV. Heart failure and other cardiac conditions are detected and tracked using the measured impedance values. CRT delay parameters are also optimized based impedance. In this manner, multiple hybrid impedance measurement configurations are exploited whereby different vectors are used to inject current and measure impedance.

Implantable systems and methods for monitoring bnp levels, hf and mi

Methods for monitoring a patient's level of B-type natriuretic peptide (BNP), and implantable cardiac systems capable of performing such methods, are provided. A ventricle is paced for a period of time to provoke a ventricular evoked response, and a ventricular intracardiac electrogram (IEGM) indicative of the ventricular evoked response is obtained. Based on the ventricular IEGM, there is a determination of at least one ventricular evoked response metric (e.g., ventricular evoked response peak-to-peak amplitude, ventricular evoked response area and/or ventricular evoked response maximum slope), and the patient's level of BNP is monitored based on determined ventricular evoked response metric(s). Based on the monitored level's of BNP, the patients heart failure (HF) condition and/or risks and/or occurrences of certain events (e.g., an acute HF exacerbation and/or an acute myocardial infarction) can be monitored.

Method for prediction, detection, monitoring, analysis and alerting of seizures and other potentially injurious or life-threatening states

The present invention provides a method for predicting seizures and for detecting seizures, and other potentially injurious or life-threatening events, optionally in conjunction with a mobile device. In an embodiment, a portable device provides epilepsy seizure prediction, detection, monitoring, analysis and alerting for epilepsy patients or other people afflicted with seizures. In an embodiment, the portable device may alert and communicate information to health care providers, caregivers and family members, emergency services, and the like. Collected data may be reviewed and analyzed for use in developing specific criteria for predicting and detecting seizures and other potentially injurious or life-threatening events.

METHOD AND SYSTEM FOR GENERATING PHYSIOLOGICAL SIGNALS WITH FABRIC CAPACITIVE SENSORS

A system for generating physiological signals using a cloth capacitive sensor, includes a cloth, at least one conductive area arranged on the cloth, a signal circuit; a capacitive sensor formed between the cloth and a human body; a resistor R, a capacitor C, an inductor L, an operational amplifier, a diode, a Schmitt trigger, CMOS, a transistor, or an IC, connected with the cloth capacitive sensor to form a charge and discharge circuit to change a signal range of frequency, cycle, voltage or current; wherein when a force, pressure, tensile force, torsion or tension is applied between the human body and the cloth, the capacitance changes, the circuit sends a signal, and the system receives the change in capacitance between the conductive cloth and the human body; wherein the change is represented by a frequency, cycle, voltage or current change. 154.-. (canceled)55. A system for generating physiological signals using a cloth capacitive sensor , comprisingat least a piece of cloth,at least one conductive area arranged on the cloth,a signal circuit;a capacitive sensor formed between the conductive cloth and a human body;a resistor R, a capacitor C, an inductor L, an operational amplifier, a diode, a Schmitt trigger, CMOS, a transistor, or an IC, connected, in series or in parallel, with the cloth capacitive sensor to form a charge and discharge circuit to change a signal range of frequency, cycle, voltage or current;wherein when a force, pressure, tensile force, torsion or tension is applied between the human body and the cloth, the capacitance changes, the circuit sends a signal, and the system receives the change in capacitance between the conductive cloth and the human body; wherein the change is represented by a frequency, cycle, voltage or current change, which is used to analyze at least one information of physiological and posture changes of human body, medium change between the human body and the cloth, or information of force applied.56. The system for ...

SENSING MOISTURE LEVEL OF HUMAN SKIN

A human skin moisture measuring device having an interdigitated resistive sensor formed on a plate-like transparent support is described, with a face designed to be placed into contact with the skin to be subjected to the moisture degree measurement. The device further comprises image sensing means turned towards the opposite face of the support and a lighting device arranged sideways relative to the support to direct the light radiation in the support at a prefixed angle. Means for processing the signal coming from the interdigitated resistive sensor and from the image sensing means give as output a value of the measured moisture degree that is normalized with respect to the actual surface of contact between skin and sensor. 1. A human skin moisture measuring device comprisingan interdigitated resistive sensor wherein said sensor is formed on a plate-like transparent support with a face to be placed into contact with skin a moisture degree of which has to be measured,image sensing means turned towards an opposite face of said support,a lighting device arranged sideways relative to said support to direct light radiation within said support at a prefixed angle, andmeans for processing a signal from said interdigitated resistive sensor,wherein said image sensing means give as output a value of measured moisture degree that is normalized with respect to a contact surface between skin and sensor.2. The device according to claim 1 , whereinsaid plate-like transparent support is a flat plate defined by a side flank or thickness andsaid lighting device is arranged substantially coplanar relative to said flat plate, whereby the plate is irradiated through its thickness.3. The device according to claim 2 , wherein an incidence angle (θ) of the light radiation emitted by said lighting device is comprised between 45° and 80°.4. The device according to claim 1 , wherein said lighting device is formed by one or more lighting sources of LED type or equivalent.5. The device ...

METHOD FOR BIOSENSOR USAGE WITH PRESSURE COMPENSATION

A biosensor is described which can obtain physiological data from an individual. The biosensor may collect electrodermal activity, skin temperature, and other information. The biosensor may be attached to the body through the use of a garment which may be fastened in multiple locations on the human body. The biosensor includes compensation for electrodermal activity measurements based on the amount of pressure applied to the electrodes that are in contact with the skin. As pressure is increased the electrodermal activity values typically increase. By compensating for the influence that pressure changes have on electrodermal activity, more accurate analysis of physiology and therefore mental state analysis may be performed. 1. A processor-implemented method for measuring physiology comprising:capturing electrodermal activity readings from a body to which electrodes are in contact with skin;collecting pressure information on an amount of pressure applied to the electrodes, which are in contact with the skin; andcompensating the electrodermal activity readings based on the pressure information which was collected.2. The method according to wherein the pressure information is collected using one or more of force sensitive resistors claim 1 , piezoelectric devices claim 1 , piezoelectric polymers claim 1 , pressure sensitive materials claim 1 , and pressure sensitive gels.3. The method according to wherein the compensating is accomplished using one or more of circuitry claim 1 , a processor claim 1 , software claim 1 , and firmware.4. The method according to wherein the compensating is accomplished real time as the electrodermal activity readings are captured.5. The method according to further comprising correcting electrodermal activity evaluations based on temperature of the skin.6. The method according to further comprising correcting electrodermal activity evaluations based on sensed humidity.7. The method according to further comprising evaluating skin temperature.8 ...

Cardio mapping system and method for cardio mapping

A method and system for determining the mechanism of cardiac arrhythmia in a patient is disclosed. The method basically entails measuring the impedance of cardiac tissue in a portion of the patient's heart using a catheter during an episode of supraventricular tachycardia to produce an iso-impedance map of that cardiac tissue on a video display and analyzing the pattern of the iso-impedance map to differentiate focal arrhythmia caused by a circumscribed region of focal firing and reentrant arrhythmia caused by a macroreentrant circuit. The method can also be used to identify regions of coherent rapidly conducting tissue e.g., Bachman's bundle or the inferoposterior pathway insertion points, to identify focal “mother rotors” throughout the left atrium that may participate in the generation and maintenance of atrial fibrillation and to identify areas of CAFE (complex atrial/fractionated electrograms) that truly reflect these mother rotors.

DEVICE FOR MEASURING BIOIMPEDANCES

The device is used to measure bioimpedances and has in each case at least one measurement electrode for each foot and each hand of a person who is to be measured. The electrodes are connected to an evaluation unit. In addition, at least one balance is used to determine a body weight of the person who is to be measured. The hand electrodes, provided for contact with the hands of the person who is to be measured, are arranged in the area of at least one positionable support element. 112.-. (canceled)13. A device for measuring bioimpedances , comprising at least one measuring electrode for each foot and for each hand of a person to be measured; an evaluation device , the electrodes being connected to the evaluation device; at least one scale for determining body weight of the person being measured; and at least one positionable support element , wherein the hand electrodes provided for contact with the hands of the person being measured are arranged in an area of the at least one positionable support element.14. The device according to claim 13 , wherein the support element is configured so as to be height adjustable.15. The device according to claim 14 , wherein the support element is positionable with a horizontal directional component.16. The device according to claim 13 , wherein the support element is rotatable.17. The device according to claim 13 , and further comprising a guide element claim 13 , wherein the support element is slidable along the guide element.18. The device according to claim 17 , and further comprising a vertical column that carries an indicator claim 17 , the guide element being attached to the vertical column.19. The device according to claim 18 , wherein the guide element has ends facing away from the vertical column claim 18 , and further comprising struts that support the ends of the guide element.20. The device according to claim 18 , wherein the guide element is height adjustable relative to the vertical column.21. The device according ...

Implantable Microphone Noise Suppression

A system and method are described for an implantable sensing system. An implantable sensor generates a sensing signal representative of an internal sensing location of a user. A sensing gate, coupled to the sensor and responsive to the sensing signal, has a sensing gate threshold value such that the sensing signal is coupled from the sensing gate to an implanted signal processor when the sensing signal has a magnitude greater than the sensing gate threshold value, and the sensing signal is blocked when the sensing signal has a magnitude less than the sensing gate threshold value. 1. A method for an implantable sensing system comprising:generating a sensing signal representative of an internal sensing location of a user;coupling the sensing signal to a sensing gate having a sensing gate threshold value;comparing the sensing signal to the sensing gate threshold value;when the sensing signal is greater than the sensing gate threshold value, coupling the sensing signal from the sensing gate to an implanted signal processor; andwhen the sensing signal is less than the sensing gate threshold value, blocking the sensing signal.2. A method according to claim 1 , wherein the sensing gate threshold value is user-controllable.3. A method according to claim 1 , wherein the sensing gate threshold value is software-controllable.4. A method according to claim 1 , wherein the sensing gate includes a sleep mode in which the sensing gate threshold value is set to a high value for reducing noise for sleeping.5. A method according to claim 1 , wherein the sensing signal is a pressure signal.6. A method according to claim 5 , wherein the pressure signal is a microphone signal.7. A method according to claim 1 , wherein the sensing signal is an electromyography signal.8. A method according to claim 1 , wherein the sensing signal is one of an electroencephalography signal and an electroneurography signal.9. A method according to claim 1 , wherein the sensing signal is an ultrasound signal. ...

Adaptive electrical capacitance volume tomography

An electrical capacitance tomography sensor comprised of a sensor having a plurality of electrodes, where each electrode is further comprised of a plurality of capacitance segments. Each of the capacitance segments of each electrode can be individually addressed to focus the electric field intensity or sensitivity to desired regions of the electrodes and the sensor.

BODY FAT MEASUREMENT DEVICE

A body fat measurement device includes: a measurement unit for measuring a shape of a measurement subject's trunk area; a breathing estimation unit that detects a change over time in the measured trunk area shape and estimates the measurement subject's breathing based on the detected change; a breathing state determination unit that determines whether or not the estimated breathing of the measurement subject is in a state suited to measurement; a state output unit that outputs the estimated breathing state to the exterior in association with a result of the determination; and a fat mass calculation unit that calculates a trunk area fat mass using the body impedance measured by a body impedance measurement unit and a trunk area size based on the trunk area shape measured by the measurement unit. 1. A body fat measurement device comprising:multiple electrodes for making contact with the surface of a measurement subject's body at the measurement subject's trunk area;an impedance measurement means that measures a body impedance of the measurement subject using the multiple electrodes;a measurement means for measuring a shape of the measurement subject's trunk area;an estimation means that detects a change over time in the trunk area shape measured by the measurement means and estimates the measurement subject's breathing based on the detected change;a determination means that determines whether or not the measurement subject's breathing estimated by the estimation means is in a state suited to measurement;a fat mass calculation means that calculates a trunk area fat mass using the body impedance measured by the impedance measurement means and a trunk area size based on the trunk area shape measured by the measurement means; anda control means that controls the impedance measurement means and the fat mass calculation means,wherein the state suited to measurement indicates a stopped state in which the measurement subject has stopped breathing after exhaling;the ...

METHOD AND APPARATUS FOR PERSONALIZED PHYSIOLOGIC PARAMETERS

Methods and apparatus combine patient measurement data with demographic or physiological data of the patient to determine an output that can be used to diagnose and treat the patient. A customized output can be determined based the demographics of the patient, physiological data of the patient, and data of a population of patients. In another aspect, patient measurement data is used to predict an impending cardiac event, such as acute decompensated heart failure. At least one personalized value is determined for the patient, and a patient event prediction output is generated based at least in part on the personalized value and the measurement data. For example, bioimpedance data may be used to establish a baseline impedance specific to the patient, and the patient event prediction output generated based in part on the relationship of ongoing impedance measurements to the baseline impedance. Multivariate prediction models may enhance prediction accuracy. 1. An apparatus to monitor a patient , the apparatus comprising:at least two electrodes coupled to circuitry to measure an impedance of the patient;at least one processor to receive the measured impedance and patient data, the at least one processor configured to determine an output based on the impedance and the patient data.2. The apparatus of claim 1 , wherein the patient data corresponds to a demographic of the patient.3. The apparatus of claim 2 , wherein the patient demographic corresponds to one or more of a gender of the patient claim 2 , an age of the patient claim 2 , or a race of the patient.4. (canceled)5. The apparatus of claim 1 , wherein the patient data corresponds to fat of the patient comprising one or more of a percent body fat of the patient claim 1 , a body mass index claim 1 , a height of the patient claim 1 , a weight of the patient claim 1 , a caliper measure of the fat of the patient claim 1 , a tape measure test of the patient claim 1 , a near infrared interactance claim 1 , images of the ...

DEVICE AND METHODS FOR MEASURING AND TREATING AN ANATOMICAL STRUCTURE

A sensor delivery device and methods of using the device are provided, wherein the sensor delivery device includes a sensor that is adapted to obtain a measurement that can be used to calculate cross-sectional area of a surrounding anatomical structure. In certain cases, the sensor is an electrode arrangement, wherein the electrode arrangement generates a current and measures voltage resulting from the current. The voltage measurement is then used to calculate conductivity of fluid in the surrounding anatomical structure and thus cross-sectional area. 1. An intravascular sensor delivery device comprising:a distal sleeve having a guidewire lumen for slidably receiving a medical guidewire;a first sensor coupled to the distal sleeve, wherein the first sensor is adapted to measure blood pressure and generate a signal representative of the blood pressure;a second sensor coupled to the distal sleeve, wherein the second sensor is adapted to measure cross-sectional area of a surrounding anatomical structure and generate a signal representative of the cross-sectional area;a proximal portion coupled to the distal sleeve, the proximal portion comprising a communication channel, wherein the communication channel communicates the signal from the first sensor and the signal from the second sensor to a location outside of the patient.2. The device of wherein the second sensor comprises an electrode arrangement.3. The device of wherein the electrode arrangement includes source electrodes and sense electrodes claim 2 , wherein the source electrodes generate a current and the sense electrodes measure voltage resulting from the current.4. The device of wherein the signal representative of the cross-sectional area is the voltage measured by the sense electrodes.5. The device of wherein the electrode arrangement includes two source electrodes and two sense electrodes.6. The device of wherein the source electrodes and the sense electrodes are ring-shaped electrodes that surround a ...

System and method for data reconstruction in soft-field tomography

A system and method for data reconstruction in soft-field tomography are provided. One method includes selecting a model domain for an EIT data set, determining a minimally anisotropic error in the model domain and correcting the model domain. The method also performing isotropization using the determined minimally anisotropic error to recover a boundary shape and isotropic conductivity for the EIT data set.

DEVICES AND SYSTEMS FOR OBTAINING CONDUCTANCE DATA AND METHODS OF MANUFACTURING AND USING THE SAME

Devices and systems for obtaining conductance data and methods of manufacturing and using the same. In at least one embodiment of a device of the present disclosure, the device is an elongated body with at least one groove defined therein, the at least one groove configured to receive one or more conductor wires therein. In another embodiment, the device is an elongated core body having a plurality of conductive elements positioned thereon and a coating to result in a device having an overall round-cross section. 1. A device , comprising:an elongated core body having a length, a perimeter, and a cross-sectional configuration;a plurality of conductive elements positioned around the perimeter of the core body and extending a majority of the length of the core body, the plurality of conductive elements surrounded by a first substantially or completely non-conductive coating;wherein the device, having the first substantially or completely non-conductive coating, has an overall round cross-section and an overall diameter between approximately 0.013″ and approximately 0.050″.2. The device of claim 1 , wherein the elongated core body has a plurality of grooves defined therein claim 1 , each of the plurality of grooves configured to receive at least one of the plurality of conductive elements therein.3. The device of claim 1 , wherein the plurality of conductive elements comprises a plurality of conductive wires.4. The device of claim 3 , wherein the elongated core body has a plurality of grooves defined therein claim 3 , each of the plurality of grooves configured to receive at least one of the plurality of conductive wires therein.5. The device of claim 4 , wherein the elongated core body is at least partially surrounded by the first substantially or completely non-conductive coating claim 4 , and wherein the plurality of conductive wires are not individually coated prior to placement within the plurality of grooves6. The device of claim 1 , wherein the cross-sectional ...

BODY COMPOSITION MEASUREMENT DEVICE

Disclosed is a body composition measurement device provided with a current electrode pair for applying current and a plurality of voltage electrode pairs for measuring voltage at a plurality of measurement points. A controller measures body fat on the basis of voltages measured at the plurality of measurement points by means of the voltage electrode pairs. The controller uses the measured voltages at the plurality of measurement points to perform integration and calculates the amount of body fat on the basis of the integration result. 1. A body composition measurement device comprising:a current electrode pair configured to apply current;a plurality of voltage electrode pairs configured to measure voltages at a plurality of measurement points; anda control unit that performs an integration using measurement values of the measurement points measured by the voltage electrode pairs and calculates a body fat amount based on the result of the integration.2. The body composition measurement device according to claim 1 , wherein the voltage electrode pairs are configured to measure voltages for a measured subject in the vicinity of a frontal plane and at an anterior belly.3. The body composition measurement device according to claim 1 , wherein the control unit calculates claim 1 , as the body fat amount claim 1 , an area of body fat in a measured cross-section of a measured subject.4. The body composition measurement device according to claim 1 , wherein the control unit estimates a distribution of body fat in a measured cross-section of a measured subject.5. The body composition measurement device according to claim 1 , wherein the control unit measures visceral fat amount as the body fat amount.6. The body composition measurement device according to claim 1 , wherein the control unit measures subcutaneous fat amount as the body fat amount.7. The body composition measurement device according to claim 1 , whereinthe control unit performs a first integration using ...

BODY FAT MEASUREMENT DEVICE

A body fat measurement device includes a plurality of electrodes including back area electrodes and upper limb electrodes, a body impedance measurement unit that measures a body impedance using the plurality of electrodes, a body composition information calculation unit that calculates a body fat mass based on the body impedance, a fitting belt for bringing the back area electrodes into contact with the surface of the measurement subject's back area in a pressurized state, and an upper limb unit that includes a gripping portion that can be gripped by the measurement subject's hand, the upper limb electrodes being provided in the gripping portion. The upper limb unit can be attached to and detached from the fitting belt. 1. A body fat measurement device comprising:a plurality of electrodes comprising back area electrodes for making contact with a surface of a back area that is an area on a back side of a measurement subject's trunk area, and upper limb electrodes for making contact with a surface of the measurement subject's upper limbs;a body impedance measurement unit for measuring a body impedance of the measurement subject's body using said plurality of electrodes;a body composition information calculation unit that calculates a body fat mass based on said body impedance measured by said body impedance measurement unit;a fitting belt for bringing said back area electrodes into contact with the surface of the measurement subject's back area in a pressurized state by being tightened around the measurement subject's trunk area; andan upper limb unit that includes comprising a gripping portion that can be gripped by the measurement subject's hand, said upper limb electrodes being provided in said gripping portion,wherein said upper limb unit can be attached to and detached from said fitting belt.2. The body fat measurement device according to claim 1 ,wherein said fitting belt comprises a first engagement member;wherein said upper limb unit includes comprises a ...

ELECTRODE DEVICE FOR MEASURING IMPEDANCE OF HUMAN BODY AND APPARATUS COMPRISING THE SAME

The present invention relates to an electrode device for measuring impedance within a human body, and to an apparatus using the same for measuring impedance within a human body and performing acupuncture treatment using the measured impedance, which can automatically and precisely determine locations of meridians within the human body, form a three-dimensional image of the determined locations, and enable acupuncture treatment to be performed precisely. The electrode device for measuring impedance within a human body comprises: a cylindrical housing member having a guide rod mounted to an open side thereof; a cylindrical electrode member configured to be pressed against the skin of a human body and moved back and forth through the open side along the guide rod; and a resilient member interposed between the cylindrical electrode member and the cylindrical housing member to resiliently move the cylindrical electrode member back and forth along the guide rod. 1. An electrode device for measuring impedances of a human body , comprising:a cylindrical housing member having a guide rod mounted to an open side thereof;a cylindrical electrode member configured to be pressed against the skin of a human body to move back and forth through the open side along the guide rod; anda resilient member interposed between the cylindrical electrode member and the cylindrical housing member to resiliently move the cylindrical electrode member back and forth along the guide rod.2. The electrode device of claim 1 , wherein the cylindrical electrode member is an electrode made of a conductive material or an electrode coated with a conductive material.3. The electrode device of claim 2 , wherein the conductive material is gold.4. The electrode device of claim 1 , wherein a protruding portion is formed at the open end of the cylindrical electrode member such that engagement between the cylindrical electrode member and the cylindrical housing member is facilitated.5. The electrode device of ...

FAT MASS MEASUREMENT APPARATUS

A fat mass measurement apparatus includes an area detection unit that detects a predetermined position in a measurement subject's trunk area and detecting a predetermined area in the trunk area using the detected position; an electrode position setting unit that sets, on the body surface at the predetermined area detected by the area detection unit, a plurality of positions along the vertical direction of the trunk area for measuring the body impedance; an impedance measurement unit that measures the body impedance by bringing the impedance measurement electrodes into contact with each of the plurality of positions that have been set; and an abdominal area fat mass calculation unit that calculates a fat volume at the predetermined area based on the body impedances at each of the plurality of positions measured by the impedance measurement and the size of the trunk area at the predetermined area. 1. A fat mass measurement apparatus for measuring a fat mass in a body based on a body impedance measured by bringing impedance measurement electrodes into contact with a measurement subject's body surface , the apparatus comprising:a position detection means for detecting a predetermined position in a trunk area of the measurement subject;an area detection means for detecting a predetermined area in the trunk area using the position detected by said position detection means;an electrode position setting means for setting, on the body surface at said predetermined area detected by said area detection means, a plurality of positions along a vertical direction of the trunk area for measuring said body impedance;an impedance measurement means for measuring said body impedance by bringing said impedance measurement electrodes into contact with each of the plurality of positions set by said electrode position setting means; anda fat mass calculation means for calculating a fat mass of said predetermined area based on said body impedances at each of said plurality of positions ...

METHOD AND APPARATUS FOR TRENDING A PHYSIOLOGICAL CARDIAC PARAMETER

The present invention relates to an implantable cardioverter-defibrillator or pacemaker whose standard circuitry is used to trend a physiological cardiac parameter using intra-cardiac impedance measurements. The trend information may be used to predict the onset of a sudden cardiac death (SCD) event. By being able to predict the onset of an SCD event, patients and their physicians may be forewarned of a life-threatening event allowing them to respond accordingly. The trend information may also be used to predict the efficacy of cardiac-related medications, monitor progress of congestive heart failure, detect the occurrence of myocardial infarction, or simply track changes in sympathetic tone. 1. A system for monitoring congestive heart failure , the system comprising:a measuring device configured to measure, using a lead, cardiac impedance of a patient;a derivation module configured to derive a physiologic parameter from the measured impedance;a trending module configured to trend the derived parameter over spaced time intervals to create trended parameter data; and analyze the trended parameter data to determine sympathetic activity; and', 'analyze the sympathetic activity and use the analysis of the sympathetic activity to monitor congestive heart failure status., 'an analyzing module configured to2. The system of claim 1 , wherein the derived parameter includes at least one of stroke volume claim 1 , ejection fraction claim 1 , and pre-ejection period.3. The system of claim 1 , wherein the derived parameter includes stroke volume.4. The system of claim 1 , wherein the derived parameter includes ejection fraction.5. The system of claim 1 , wherein the derived parameter includes pre-ejection period.6. The system of claim 1 , wherein the analyzing module is configured to:analyze the trended parameter data to determine changes in sympathetic activity;analyze the changes in sympathetic activity; anduse the analysis of the changes in sympathetic activity to monitor ...

SYSTEM AND CIRCUIT FOR DISTRIBUTION OF PRECISE CURRENTS TO NUMEROUS PATIENT ELECTRODES AND FOR NON-INVASIVE PATIENT-ELECTRODE VOLTAGE MEASUREMENTS

Apparatus for electrically connecting measurement apparatus to a biological subject, the apparatus including a signal delivery circuit including a current buffer having a current buffer input for receiving a signal from a signal source and a current buffer output for supplying a current to an electrode attached to the biological subject, and a voltage buffer having a voltage buffer input coupled to the current buffer output and a voltage buffer output for providing a voltage signal indicative of a voltage at the electrode, to a sensor. 1. Apparatus for electrically connecting measurement apparatus to a biological subject , the apparatus including a signal delivery circuit including: a current buffer input for receiving a signal from a signal source; and,', 'a current buffer output for supplying a current to an electrode attached to the biological subject; and,, 'a current buffer having a voltage buffer input coupled to the current buffer output; and,', 'a voltage buffer output for providing a voltage signal indicative of a voltage at the electrode, to a sensor., 'a voltage buffer having2. Apparatus according to claim 1 , wherein the current buffer is a current conveyor.3. Apparatus according to claim 1 , wherein the voltage buffer is an amplifier connected as an output follower.4. Apparatus according to claim 1 , wherein the apparatus includes an offset control circuit coupled between the voltage buffer output and the current buffer input.5. Apparatus according to claim 4 , wherein the offset control circuit includes an integrator coupled between the voltage buffer output and the current buffer input.6. Apparatus according to claim 4 , wherein the offset control circuit is used to control a DC offset at the electrode.7. Apparatus according to claim 1 , wherein the signal delivery circuit includes a negative impedance circuit coupled between the voltage buffer output and the current buffer output.8. Apparatus according to claim 7 , wherein the negative impedance ...

ELECTRODE SENSOR AND USE OF ELECTRODE SENSOR AS EIT ELECTRODE

Electrode sensor comprising an array of spaced apart individual contact elements (), and an interface structure () for forming contact between said contact elements and the skin; said interface structure comprising an interface layer of an essentially electrically insulating or poorly electrically conducting material () defining a skin () contact surface on one side and an array contact surface on the other side of the interface layer, a first pattern of an electrically conducting material on the array contact surface, a second pattern of an electrically conducting material on the skin contact surface, and electrical pathways () connecting the first pattern with the second pattern; whereas, the first pattern comprises pattern elements, each individual contact element () comprises a contacting surface area large enough to cover several pattern elements of said first pattern when contacting the array contact surface of the interface structure, and by contacting distinct sections of the first pattern with said individual contact elements, groups of electrical pathways establish contact further with distinct sections of the second pattern, so that an individual contact element () defines an individual effective electrode on the skin contact surface. Method of manufacturing said electrode sensor, comprising the steps of: providing said interface structure, creating a first pattern of an electrically conducting material on its array contact surface, a second pattern of an electrically conducting material on its skin contact surface, electrically conducting pathways connecting the first pattern with the second pattern, and contacting sections of the electrically conducting first pattern with an array of spaced apart contact elements. 136-. (canceled)37. An electrode sensor for electrical impedance tomography , comprising:an array of spaced apart individual contact elements;an interface structure configured for forming contact between the array of contact elements and skin ...

Mri-guided devices and mri-guided interventional systems that can track and generate dynamic visualizations of the devices in near real time

An MRI-guided medical device includes an elongated sheath, an elongated dilator, and an elongated needle. The sheath has a distal end, an opposite proximal end, and a central lumen extending between the proximal and distal ends. The sheath comprises MRI-compatible material and includes a tracking member located adjacent to the sheath distal end that is visible in an MRI image. The dilator comprises MRI-compatible material and is movably disposed within the sheath lumen. A distal end of the dilator is configured to extend outwardly from the sheath distal end and dilator includes at least one tracking member that is visible in an MRI image. The needle is movably disposed within the dilator lumen and is movable between stored and operative positions relative to the dilator. An RF shield may be coaxially disposed within the elongated sheath so as to surround a portion of the sheath central lumen.

Sem scanner sensing apparatus, system and methodology for early detection of ulcers

A handheld, conforming capacitive sensing apparatus configured to measure Sub-Epidermal Moisture (SEM) as a mean to detect and monitor the formation of pressure ulcers. The device incorporates an array of electrodes which are excited to measure and scan SEM in a programmable and multiplexed manner by a battery-less RF-powered chip. The scanning operation is initiated by an interrogator which excites a coil embedded in the apparatus and provides the needed energy burst to support the scanning/reading operation. Each electrode measures the equivalent sub-epidermal capacitance corresponding and representing the moisture content.

SYSTEM AND METHOD FOR TASK-LESS MAPPING OF BRAIN ACTIVITY

A computing device for use in a system for mapping brain activity of a subject includes a processor. The processor is programmed to select a plurality of measurements of brain activity that is representative of at least one parameter of a brain of the subject during a resting state. Moreover, the processor is programmed to compare at least one data point from each of the measurements with a corresponding data point from a previously acquired data set from at least one other subject. The processor is also programmed to produce at least one map for each of the measurements based on the comparison of the resting state data point and the corresponding previously acquired data point. The processor may also be programmed to categorize the brain activity in a plurality of networks in the brain based on the map. 1. A computing device for use in a system for task-less mapping of brain activity of a subject , the computing device comprising a processor programmed to:select a plurality of measurements of brain activity that is representative of at least one parameter of a brain of the subject during a resting state;compare at least one data point from each of the plurality of measurements with a corresponding data point from a previously acquired data set from at least one other subject;produce at least one map for each of the plurality of measurements based on the comparison of the at least one resting state data point and the corresponding previously acquired data point; andcategorize the brain activity in a plurality of networks in the brain based on the at least one map.2. A computing device in accordance with claim 1 , wherein the processor is programmed to select a plurality of voxels from an image of the brain.3. A computing device in accordance with claim 1 , further comprising a communication interface coupled to the processor and configured to receive at least one signal representative of the plurality of measurements of the brain activity.4. A computing device in ...

Application of electric fields to the lung as therapy for pulmonary edema

System and method of applying electric fields to a patient's lung(s) to reduce pulmonary edema. The system includes a first electrode and a second electrode, at least one of which is associated with the lung. The electric field can be controlled so as to modulate a level of fluid in the lung.

DEVICE FOR MODULAR ANALYSIS

The device is provided with at least one analysis apparatus for analyzing at least one biological parameter of a living being. The analysis apparatus has at least one data input for recording measured data of at least one sensor. The sensor measures at least one biological parameter of the living being. The analysis apparatus also has at least one output apparatus for an analysis result. The analysis apparatus has a control unit and a program memory. The program memory stores a plurality of program modules, which can be activated by the control unit according to an externally specifiable control instruction alternatively or in partial or complete combination with each other in such a way that the activated program modules provide the data for the selected analysis result. 110-. (canceled)11. A device comprising at least one evaluation apparatus for evaluating at least one biological parameter of a living organism , which apparatus includes at least one data input for acquiring measurement data from at least one sensor , which measures at least one biological parameter of the living organism , and at least one output apparatus for an evaluation result , wherein the evaluation apparatus further includes a control unit and a program memory , wherein the program memory contains a plurality of program modules that are activateable selectively or in partial or complete combination by the control unit as a function of an externally specifiable control instruction so that the activated program modules provide data for the selected evaluation result.12. The device according to claim 11 , wherein the sensor and the evaluation feature are connected to each other by a data transfer link.13. The device according to claim 11 , wherein a display apparatus and the evaluation apparatus are connected to each other by a data transfer link.14. The device according to claim 11 , wherein the evaluation apparatus comprises an interface for an input of data not metrologically acquired.15. ...

BODY WEIGHT MANAGEMENT DEVICE

A device includes a body weight obtainment unit for obtaining measurement data; a storage unit for storing the measurement data; a target calculation unit that, based on the measurement data in, calculates a target diurnal fluctuation amount including a body weight fluctuation amount during sleep and a body weight diurnal target increase/decrease amount; and a computation unit that, based on the target diurnal fluctuation amount, calculates a target value to serve as a target when measuring a pre-sleep body weight value at a second timing before the measurement subject sleeps relative to a post-waking body weight value that is measured at a first timing after the measurement subject wakes. The target calculation unit calculates the diurnal target increase/decrease amount based on the measurement data in the storage unit so that the diurnal target increase/decrease amount is within a predetermined increase/decrease percentage range of the post-waking body weight value. 1. A body weight management device comprising:a body weight/body composition meter that obtains measurement data in which a body weight measurement value for a measurement subject and a measurement day/time are associated with each other;a storage unit that stores said measurement data obtained by said body weight/body composition meter;a target obtainment unit that, based on said measurement data in said storage unit, calculates a target diurnal fluctuation amount including a body weight fluctuation amount during sleep and a body weight diurnal target increase/decrease amount; anda computation unit that, based on the target diurnal fluctuation amount obtained by said target obtainment unit, calculates a target value to serve as a target to be achieved when measuring a pre-sleep body weight value at a second timing near when the measurement subject sleeps, based on a post-waking body weight value measured at a first timing after the measurement subject wakes,wherein said target obtainment unit ...

MRI-GUIDED CATHETERS

An MRI-compatible catheter that reduces localized heating due to MR scanner-induced currents includes an elongated flexible shaft having a distal end portion and an opposite proximal end portion. A handle is attached to the proximal end portion and includes an electrical connector interface configured to be in electrical communication with an MRI scanner. One or more RF tracking coils are positioned adjacent the distal end portion of the shaft. Each RF tracking coil includes a conductive lead, such as a coaxial cable, that extends between the RF tracking coil and the electrical connector interface and electrically connects the RF tracking coil to an MRI scanner. In some embodiments of the present invention, the conductive lead has a length sufficient to define an odd harmonic/multiple of a quarter wavelength of the operational frequency of the MRI Scanner, and/or includes a series of pre-formed back and forth segments along its length. 1. An MRI-compatible catheter , comprising:an elongated flexible shaft having a distal end portion, and an opposite proximal end portion;an electrical connector interface configured to be in electrical communication with an MRI scanner; andat least one RF tracking coil positioned adjacent the distal end portion of the flexible shaft, wherein the at least one tracking coil includes a conductive lead extending between the at least one RF tracking coil and the electrical connector interface and configured to electrically connect the at least one tracking coil to the MRI scanner, and wherein the conductive lead includes a series of pre-formed back and forth segments along its length.2. The catheter of claim 1 , wherein the conductive lead is a coaxial cable.3. The catheter of claim 1 , wherein the at least one RF tracking coil comprises a plurality of tracking coils claim 1 , each attached to a separate conductive lead claim 1 , and wherein each conductive lead includes a series of back and forth segments along its length.4. The catheter ...

FLUID LEVEL INDICATOR DETERMINATION

A method for use in analysing impedance measurements performed on a subject, the method including, in a processing system, determining at least one impedance value at each of a number of frequencies, each impedance value representing the impedance of a segment of the subject, determining a dispersion parameter value indicative of a dispersion of the impedance values and, determining an indicator based at least in part on the dispersion parameter value. 1. A method for use in analysing impedance measurements performed on a subject , the method including , in a processing system:determining at least one impedance value at each of a number of frequencies, each impedance value representing the impedance of a segment of the subject;determining a dispersion parameter value indicative of a dispersion of the impedance values; and,determining an indicator based at least in part on the dispersion parameter value.2. A method according to claim 1 , wherein the method includes claim 1 , in the processing system:determining first and second dispersion parameter values for first and second body segments respectively; and,determining the indicator using the first and second dispersion parameter values.3. A method according to claim 2 , wherein the first body segment is an affected body segment and the second body segment is an unaffected body segment.4. A method according to claim 2 , wherein at least one of the body segments is a dominant limb and the other body segment is a non-dominant limb.5. A method according to claim 2 , wherein the first body segment is a different body segment to the second body segment.6. A method according to claim 2 , wherein the method includes claim 2 , in the processing system:determining a predicted dispersion parameter value for the first body segment using the second dispersion parameter value;determining the indicator using the first and predicted dispersion parameter values.7. A method according to claim 6 , wherein predicted dispersion ...

METHOD AND DEVICE FOR QUALITY ASSESSMENT OF AN ELECTRICAL IMPEDANCE MEASUREMENT ON TISSUE

The present invention relates to a method of assessing the quality of an electrical impedance measurement on tissue of a subject, the method comprising: performing the impedance measurement on a tissue region of said tissue of the subject, whereby impedance data is obtained, said data comprising at least one impedance value measured in said tissue region; applying an evaluation algorithm to the obtained impedance data, whereby the quality of the impedance measurement is assessed; and presenting the assessed quality of the impedance measurement such that a decision can be made on whether to use the impedance measurement for diagnosing a condition of said tissue of the subject. The invention also relates to a device for electrical impedance measurement on tissue of a subject. 115-. (canceled)16. A device for electrical impedance measurement on tissue of a subject , the device comprising:an impedance signal unit arranged to obtain impedance data of a tissue region of said tissue of the subject, said data comprising at least one impedance value measured in said tissue region;an evaluation unit arranged to apply an evaluation algorithm to the obtained impedance data, whereby the quality of the impedance measurement is assessed; anda presenting unit arranged to present the assessed quality of the impedance data such that a decision can be made on whether to use the impedance data for diagnosing a condition of said tissue of the subject.17. The device of claim 16 , wherein at least the impedance signal unit is arranged in an arrangement adapted to be handheld.18. The device of claim 16 , wherein the plurality of impedance values include magnitude and/or phase at a plurality of frequencies measured at a plurality of tissue depths of the tissue.19. The device of claim 16 , wherein said presenting unit is configured to mediate the assessed quality such that it can be perceived by a human operator.20. The device of claim 16 , wherein said presenting unit is configured to ...

BODY FAT MEASUREMENT DEVICE

A body fat measurement device includes a trunk area dimension measurement unit in which is provided a trunk area dimension detection unit for detecting a dimension of a measurement subject's trunk area. The trunk area dimension measurement unit has a frame shape that can be disposed surrounding the measurement subject's trunk area, and includes a base portion whose position relative to the trunk area does not change in a state where the trunk area dimension measurement unit is disposed surrounding the trunk area, and a mobile portion that is attached in a movable state to the base portion and whose position relative to the trunk area can change in a state where the trunk area dimension measurement unit is disposed surrounding the trunk area. The trunk area dimension detection unit includes at least a non-contact range sensor provided in the mobile portion. 1. A body fat measurement device comprising:a plurality of electrodes for making contact with predetermined areas of the surface of a measurement subject's body;a body impedance measurement unit that measures a body impedance of the measurement subject's body using said plurality of electrodes;a trunk area dimension detection unit for detecting a trunk area dimension of the measurement subject;a frame-shaped trunk area dimension measurement unit in which said trunk area dimension detection unit is provided and that is capable of being disposed so as to surround the measurement subject's trunk area;a body shape information measurement unit that measures a dimension of the measurement subject's trunk area based on information detected by said trunk area dimension detection unit; anda body fat mass calculation unit that calculates a body fat mass based on the body impedance measured by said body impedance measurement unit and the trunk area dimension measured by said body shape information measurement unit,wherein said trunk area dimension measurement unit includes a base portion whose position relative to the ...

Skin Permeation Device for Analyte Sensing or Transdermal Drug Delivery

Devices, systems, kits and methods for increasing the skin's permeability controlled by measured skin electrical parameter are described herein. They may be used for transdermal drug delivery and/or analyte extraction or measurement. The controlled abrasion device contains (i) a hand piece, (ii) an abrasive tip, (iii) a feedback control mechanism, (iv) two or more electrodes, and (v) an electrical motor. Preferably the feedback control mechanism is an internal feedback control mechanism. In this embodiment, the abrasive tip contains two electrodes, i.e. both the source electrode and the return electrode. In another embodiment, the feedback control mechanism is an external feedback control. In the preferred embodiment for external feedback control, the device contains a co-axial or concentric arrangement of the two electrodes. In this embodiment, the abrasive tip contains the source electrode and the return electrode is located at the proximal end of the hand piece. The abrasive tip can be made of any material with a surface that can abrade skin. The material can be conductive or non-conductive. The controlled abrasion device may be provided in a kit, where the kit contains the device, one or more abrasive tips, optionally with a wetting fluid. The method for increasing the skin's permeability requires applying the controlled abrasion device to a portion of the skin's surface for a short period of time. The desired level of skin impedance, and thus the resulting permeability of the treated site, can be set at a predetermined value. Alternatively, the level of skin impedance can be selected based on the desired level of skin integrity, the subject's sensation of discomfort, or the duration of the application. The device contains a control mechanism which uses an appropriate algorithm or signal processing on the conductivity information provided by the electrodes to determine when the desired level of skin permeability has been reached. Once the desired ...

SYSTEM AND METHOD FOR SYSTOLIC INTERVAL ANALYSIS

A system and method provide for systolic interval analysis. In an example, an implantable device measures a cardiac impedance signal. A transformation of the cardiac impedance interval is generated. The device also measures a heart sound signal. A time interval between a point on the transformed signal of the cardiac impedance signal and a point on the heart sound signal is calculated. 1. A processor-readable medium , comprising instructions that , when performed by the processor , cause the processor to:obtain information indicative of an acoustic signal from an implantable acoustic sensor;identify a first heart sound feature in the information indicative of the acoustic signal;obtain information indicative of a cardiac impedance from an implantable cardiac impedance sensor;transform the information indicative of the cardiac impedance to obtain transformed cardiac impedance information;identify a first cardiac impedance feature in the transformed cardiac impedance information;determine a first interval between the identified first heart sound feature in the information indicative of the acoustic signal and the identified first cardiac impedance feature in the transformed cardiac impedance information; anddetermine a heart failure decompensation status using information about the determined first interval.2. The processor-readable medium of claim 1 , wherein the first interval corresponds to a left ventricular ejection time (LVET) claim 1 , and wherein the instructions include instructions that claim 1 , when performed by the processor claim 1 , cause the processor to:determine a second interval corresponding to a pre-ejection period (PEP);determine a relative indication of information between the PEP and the LVET; anddetermine the heart failure decompensation status using the relative indication of information.3. The processor-readable medium of claim 2 , wherein the instructions to determine the relative indication of information include instructions to determine ...

SYSTEM, METHOD AND APPARATUS FOR MEASURING BLOOD FLOW AND BLOOD VOLUME

A method of calculating blood flow in an organ of a subject using output radiofrequency signals transmitted to the organ and input radiofrequency signals received from the organ, the method comprises determining a phase shift of the input radiofrequency signals relative to the output radiofrequency signals and using the phase shift to calculate the blood flow in the organ. 1. An apparatus for determining blood flow in an organ of a subject from output radiofrequency signals transmitted to the organ and input radiofrequency signals received from the organ , the apparatus comprising:electronic circuitry having an envelope elimination unit designed and configured to reduce or eliminate amplitude modulation of said input radiofrequency signals thereby to provide input radiofrequency signals of substantially constant envelope; anda signal processing unit for determining the blood flow in the organ using said input radiofrequency signals of substantially constant envelope.2. The apparatus of claim 1 , wherein said signal processing unit is designed and configured to determine a phase shift of the input radiofrequency signals relative to the output radiofrequency signals of substantially constant envelope claim 1 , said phase shift being indicative of the blood flow in the organ.3. The apparatus of claim 1 , wherein said envelope elimination unit is designed and configured to maintain a phase modulation of said input radiofrequency signals.4. The apparatus of claim 1 , wherein said envelope elimination unit comprises a limiter amplifier.5. The apparatus of claim 1 , further comprising a mixer claim 1 , for mixing the output radiofrequency signals and said input radiofrequency signals of substantially constant envelope thereby to provide a mixed radiofrequency signal.6. The apparatus of claim 5 , wherein said electronic circuitry is designed and configured to filter out a portion of said mixed radiofrequency signal so as to substantially increase a signal-to-noise ratio of ...

SLEEP APNEA DETECTION SYSTEM

This document provides methods and materials (e.g., systems) related to assessing sleep conditions (e.g., sleep apnea). 1. A method for assessing sleep of a human in a normal sleep environment , wherein said method comprises:(a) detecting audible sounds from said human in said normal sleep environment using a mobile electronic device having a sound sensor, and(b) determining whether said audible sounds are indicative of normal sleep or a disorder present in said human.28-. (canceled)9. The method of claim 1 , wherein said audible sounds comprise snoring sounds of said human claim 1 , and said determining step comprises determining that said audible sounds are indicative of normal sleep.10. (canceled)11. The method of claim 1 , wherein said audible sounds comprise snoring sounds of said human claim 1 , and said determining step comprises determining that said audible sounds are indicative of said disorder.1214-. (canceled)15. The method of claim 11 , wherein said method comprises informing said human via said mobile device that said human has said disorder.16. The method of claim 1 , wherein said audible sounds comprise snoring sounds of said human claim 1 , and said determining step comprises determining that said audible sounds are indicative of sleep apnea.17. The method of claim 16 , wherein said method comprises informing said human via said mobile device that said human has sleep apnea.18. The method of claim 1 , wherein said audible sounds comprise snores of said human claim 1 , and said determining step comprises assessing the amplitude of said snores claim 1 , the interval between said snores claim 1 , the frequency composition of snores claim 1 , or the duration of snores.19. The method of claim 1 , wherein said audible sounds comprise snores of said human claim 1 , and said determining step comprises assessing the amplitude of said snores claim 1 , the interval between said snores claim 1 , the frequency composition of snores claim 1 , and the duration of ...

Catheter balloon methods and apparatus employing sensing elements

An apparatus for medical diagnosis and/or treatment is provides. The apparatus includes a flexible substrate forming an inflatable body and a plurality of sensing elements disposed on the flexible substrate. The plurality of sensing elements are disposed about the inflatable body such that the sensing elements are disposed at areas of minimal curvature of the inflatable body in a deflated state.

SURGICAL TISSUE MONITORING SYSTEM

A tissue monitoring system includes an introducer having an inflatable section and a plurality of electrodes disposed thereon. The electrodes are alternatively connected to an electrode contact system which includes at least one signal line and at least one measurement line for taking readings about a circumferential segment of tissue encompassed by the electrodes. 1. A method of monitoring tissue comprising:placing an introducer having an inflatable section and a plurality of electrodes disposed about the inflatable section adjacent to a section of tissue;distending the first inflatable section of the introducer;imposing an electrical signal on the tissue using a subset of the plurality of electrodes selected for an electrode contact system;measuring a resulting potential with the subset of the plurality of electrodes of the electrode contact system; andshifting the electrode contact system to alternate placement of the electrode contact system within the tissue.2. The method of claim 1 , wherein the step of shifting the electrode contact system includes electronically shifting each contact of the electrode contact system to encompass a different subset of the plurality of electrodes.3. The method of claim 2 , wherein electronically shifting each contact includes shifting each contact to an adjacent electrode on the inflatable section of the introducer.4. The method of claim 1 , wherein the introducer further includes a shaft extending through the introducer claim 1 , and wherein the step of shifting the electrode contact system includes rotating the shaft to shift the electrode contact system clockwise or counterclockwise around a circumferential segment of the tissue.5. The method of claim 1 , further comprising repeating the step of shifting the electrode contact system until an entire circumference of the tissue is characterized.6. The method of claim 1 , wherein the step of imposing an electrical signal includes attaching two electrodes of the subset of the ...

BIOELECTRICAL IMPEDANCE MEASURING APPARATUS, SEMICONDUCTOR DEVICE, AND CONTROL METHOD FOR BIOELECTRICAL IMPEDANCE MEASURING APPARATUS

A current supply unit supplies a current between first and second current output terminals. A voltage measurement unit measures a voltage input to first and second voltage input terminals. A control circuit causes a first switch unit to connect the first current output terminal to a first terminal of a reference resistor and to connect the second current output terminal to a second terminal of the reference resistor, causes a second switch unit to connect the first voltage input terminal to the first terminal of the reference resistor and to connect the second voltage input terminal to the second terminal of the reference resistor, and causes a voltage measurement unit to measure a voltage between the first and second voltage input terminals, thereby performing self-diagnosis of a path through which a current flows. 1. A bioelectrical impedance measuring apparatus comprising:a reference resistor;first and second current supply electrodes that contact a living organism to be measured;first and second voltage measurement electrodes that contact the living organism;a current supply unit that supplies a current between first and second current output terminals;a voltage measurement unit that measures a voltage input to first and second voltage input terminals;a first switch unit that connects the first current output terminal to one or both of the first current supply electrode and a first terminal of the reference resistor, and connects the second current output terminal to one or both of the second current supply electrode and a second terminal of the reference resistor;a second switch unit that connects the first voltage input terminal to one or both of the first voltage measurement electrode and the first terminal of the reference resistor, and connects the second voltage input terminal to one or both of the second voltage measurement electrode and the second terminal of the reference resistor; anda control circuit that controls the first and second switch units to ...

Apparatus and methods for performing electrotherapy

A circumferential electrode includes a moisture-containing layer comprising a first side and an electrically conductive layer on the moisture-containing layer, the electrically conductive layer including a second side and a third side opposite the second side, the third side of the electrically conductive layer contacting the first side of the moisture-containing layer. The circumferential electrode further includes a barrier layer on the electrically conductive layer, the barrier layer including a fourth side adjacent to the second side of the electrically conductive layer. The circumferential electrode further includes a bulk region and a border region, the border region completely surrounding the bulk region, and the electrically conductive layer is in the bulk region but is not in the border region. The circumferential electrode can be part of an electrotherapy system which can be used to apply various current waveforms to patients in order to treat a variety of ailments and conditions.

Multi-ventricular site timing optimization using cardiogenic impedance

A method of calculating a timing delay for an implantable medical device based on cardiogenic impedance estimates cardiogenic impedance from a signal between a first electrode and a second electrode positioned in at least one chamber of a heart. The method also determines the timing delay based on the estimated cardiogenic impedance.

PHYSIOLOGICAL STATUS INDICATOR APPARATUS AND METHOD

A processor circuit can be configured to obtain a first multidimensional vector. The first multidimensional vector can include dimensions corresponding to respective first conductivity characteristics obtained from different implantable electrode configurations associated with a subject. The processor circuit can also be configured to obtain a second multidimensional vector or vector space. The second multidimensional vector or vector space can include dimensions corresponding to respective second conductivity characteristics obtained from such different electrode configurations associated with the same or a different subject. The processor circuit can also provide a physiological status indicator that can be obtained at least in part by performing a vector comparison of the first multidimensional vector to the second multidimensional vector space or vector. 1. An apparatus comprising:a processor circuit, configured toobtain a first multidimensional vector, comprising dimensions corresponding to respective first conductivity characteristics obtained from different implantable electrode configurations associated with a subject;obtain a second multidimensional vector space or vector, comprising dimensions corresponding to respective second conductivity characteristics obtained from the different electrode configurations associated with the same or a different subject, wherein the first conductivity characteristics are of the same type as the second conductivity characteristics, and wherein the different electrode configurations corresponding to the respective dimensions of the first multidimensional vector are of the same type as the different electrode configurations corresponding to the respective dimensions of the second multidimensional vector space or vector; andproviding a physiological status indicator obtained at least in part by performing a vector comparison of the first multidimensional vector to the second multidimensional vector space or vector.2. The ...

Systems and methods for making and using medical ablation systems having mapping catheters with improved anchoring ability

A mapping catheter includes an elongated body for inserting into patient vasculature. A distal end of the elongated body includes a distal portion that includes a plurality of electrodes, a proximal portion disposed proximal to the distal portion, and a reduced-dimension portion disposed between the proximal and distal portions. The distal end is formed, at least in part, from a memory shape material that bends into a preformed shape upon release from a confined space. The preformed shape includes a first loop formed, at least in part, by the distal portion. The first loop is transverse to a longitudinal axis of the proximal portion. The reduced-dimension portion is configured and arranged to bend such that the reduced-dimension section advances distally through the first loop when the first loop is held in a fixed position and a force is applied distally along the longitudinal axis of the proximal portion.

Emergency Medical Diagnosis and Communications Device

A portable emergency medical device capable of communicating with a remote location preferably as a cellular telephone that can measure one or more human vital parameters such as pulse rate, body temperature, skin moisture, blood pressure, ECG or blood chemistry and can receive symptoms from a user either by voice recognition or by keypad and can provide an expert medical diagnosis. The device can store a complete medical history for one or more users and can use an expert system to make the diagnosis. The device can make an emergency medical call either on command or automatically requesting help and optionally supplying medical information and/or GPS location information. 1. A personal medical diagnosis apparatus comprising:a cellular telephone module including a processor and memory;a medical expert system disposed in said memory and executable on said processor;a medical probe that measures at least one human medical parameter, said probe being in data communication with said medical expert system; andan input device, including a keyboard and circuitry through which the medical expert system receives symptom data;the expert system receiving imputed symptom data and at least one medical parameter and making a medical diagnosis.2. The personal medical diagnosis apparatus of further comprising a GPS receiver in communication with said processor claim 1 , wherein said processor is adopted to report a geographic location of said medical diagnosis apparatus to a remote station.3. The personal medical diagnosis apparatus of further comprising a housing wherein said medical probe is at least one of:a blood pressure sensor in or deployable from said housing;a pulse rate sensor in or deployable from said housing;a body temperature sensor in or deployable from said housing, or;an ECG interface in or deployable from said housing.4. The personal medical diagnosis apparatus of further comprising a housing wherein said medical probe is at least one of:a blood pressure sensor ...

Apparatus, system and method for detection and delivery of a medicinal dose

An apparatus is disclosed as part of a system for tracking and confirming delivery of a medicinal dose to a user. The apparatus includes a detector. The detector is secured to and communicatively coupled to the user and is capable of detecting a current flow through the user's body. The current flow is produced when the user makes contact with the apparatus. The apparatus includes at least two contact areas connected to a power source where a circuit and, hence, a current path is completed through the user's body as the user makes contact with the apparatus. The current flow is detected by the detector, which is coupled to the user. Also disclosed is an apparatus for tracking and confirming delivery of a medicinal dose to a user where the apparatus includes an acoustic detector. Upon loading the dose into a chamber an acoustic vibration is generated. The vibration is detected and correlated with a current flow that is produced when the user makes contact with the apparatus. The combined event of vibration detection and current flow detection confirms that the dose is loaded and the user is in contact with the apparatus and ready to receive the dose.

Health monitoring appliance

A heart monitoring system for a person includes one or more wireless nodes forming a wireless network; a wearable body sensor having a wireless transceiver adapted to communicate with the one or more wireless nodes.

SWALLOWABLE CAPSULE FOR MONITORING A CONDITION

A swallowable capsule () is provided with a drug reservoir () and at least one sensor (). The drug reservoir () is arranged to hold a pharmaceutical composite. A wall () of the drug reservoir () comprises at least one opening for allowing fluid from the surroundings of the capsule () to enter the drug reservoir () and for allowing dissolved drug or liberated particles of the pharmaceutical composite to enter the surroundings of the capsule (). The at least one sensor () is provided for monitoring a condition of the surroundings of the capsule (). 110. A swallowable capsule () , comprising:{'b': 18', '12', '10', '18', '10, 'a drug reservoir () for holding a pharmaceutical composite, with a wall () comprising at least one opening for allowing fluid from the surroundings of the capsule () to enter the drug reservoir () and for allowing dissolved drug or liberated particles of the pharmaceutical composite to enter the surroundings of the capsule (), and'}{'b': 13', '10, 'at least one sensor () for monitoring a condition of the surroundings of the capsule ().'}210181018. A swallowable capsule () as claimed in claim 1 , wherein the drug reservoir () can be opened or detached from the capsule () in order to allow placement of the pharmaceutical composite in the reservoir ().310181212. A swallowable capsule () as claimed in claim 1 , wherein the drug reservoir () comprises a meshed wall () claim 1 , the meshed wall () comprising the at least one opening.41012. A swallowable capsule () as claimed in claim 3 , wherein the meshed wall () is injection molded.51012. A swallowable capsule () as claimed in claim 3 , wherein the meshed wall () comprises meshed metal wires.61013. As swallowable capsule () as claimed in claim 1 , wherein the sensor () is capable of providing time-stamped data.7101513. A swallowable capsule () as claimed in claim 1 , further comprising a transmitter () coupled to the sensor () for transmitting sensor information regarding the monitored condition to an ...

METHOD FOR IMPROVING IMAGING RESOLUTION OF ELECTRICAL IMPEDANCE TOMOGRAPHY

The present disclosure provides a method for improving imaging resolution of electrical impedance tomography (EIT). More specifically, the present disclosure forms virtual electrode(s) using an electric current steering technique, which is used to improve imaging resolution of an EIT system without physically increasing a number of conducting electrodes. The EIT system of the present disclosure may includes a plurality of conducting electrodes, at least one signal generator, at least one signal receiver and at least one electric current steering device. In other words, the present disclosure applies both the electric current steering technique and the virtual electrode technique to EIT. Consequently, imaging resolution of EIT can be improved without physically increasing the number of conducting electrodes. 1. A method for improving imaging resolution of electrical impedance tomography (EIT) using a plurality of conducting electrodes on the surrounding of or inside a tissue structure , comprising the steps of:(1) inputting an electric current into the tissue structure through at least two of the plurality of conducting electrodes, and outputting the electric current from at least other one of the plurality of conducting electrodes;(2) forming a virtual electrode between the at least two of the plurality of conducting electrodes by inputting an electric current ratio to control the electric current via an electric current steering device;(3) measuring an electric potential using the at least two of the plurality of conducting electrodes, except these conducting electrodes for inputting and outputting the electric current, to obtain electric current and electric potential distributions corresponding to the plurality of conducting electrodes and the virtual electrode in the tissue structure; and(4) performing an image conversion processing according to the electric current and electric potential distributions to profile an image for a specific region in the tissue ...

APPARATUS FOR DETECTING AN APNEA/HYPOPNEA CONDITION

While remarkably reducing the botheration and burden on the subject, an apnea/hypopnea condition can be detected correctly and easily, and the type of the condition can be identified. A detecting apparatus for detecting an apnea/hypopnea condition of a living body, includes: an electric current applying electrode section to supply an electric current via electrodes into a cervical region of the living body; a measurement electrode section to measure an impedance of the cervical region by the electric current; an analysis section which detects an apnea/hypopnea condition based on the measured impedance; and an output section which outputs the result of detection. 1. A detecting apparatus for detecting an apnea/hypopnea condition of a living body , including:an electric current applying electrode section configured to supply an electric current via electrodes into a cervical region of the living body;a measurement electrode section configured to measure impedance of the cervical region by the electric current;an analysis section configured to detect an apnea/hypopnea condition based on the measured impedance; andan output section configured to output the result of detection.2. The detecting apparatus according to claim 1 , wherein the detecting apparatus further includes a respiration sensor which is placed on a region of the living body other than the cervical region claim 1 , and configured to output a signal caused by respiration or respiratory effort of the living body claim 1 , andthe analysis section is configured to identify types of the apnea/hypopnea condition based on the measured impedance and the output signal of the respiration sensor.3. The detecting apparatus according to claim 2 , whereinthe output section is configured to visualize the identification result.4. The detecting apparatus according to claim 2 , wherein the analysis section is configured to identify whether the living body is in an obstructive apnea/hypopnea condition or a central apnea/ ...

BODY CONDITION INFORMATION PROCESSING APPARATUS, NON-TRANSITORY COMPUTER READABLE RECORDING MEDIUM, AND METHOD FOR PROCESSING BODY CONDITION INFORMATION

A condition information processing apparatus (A) includes: an obtaining section () that obtains information relating to a bioelectrical impedance measured by means of impressing an alternating current of a predetermined frequency to a body surface of a user. An operating section () calculates an index relating to a body condition on the basis of the information relating to the bioelectrical impedance. 1. A condition information processing apparatus comprising:an obtaining section adapted for obtaining information relating to a bioelectrical impedance measured by means of impressing an alternating current of a predetermined frequency to a body surface of a user; andan operating section adapted for calculating an index relating to a body condition on the basis of the information relating to the bio electrical impedance.2. The condition information processing apparatus according to claim 1 , further comprising a condition estimating section adapted for estimating the body condition on the basis of a newly calculated index relating to the body condition and a past index relating to the body condition recorded as a measurement history.3. The condition information processing apparatus according to claim 1 , further comprising:a pair of current applying electrodes that is capable of contacting the body surface;a pair of voltage measuring electrodes that is capable of contacting the body surface;an alternating current applying section adapted for applying an alternating current to the current applying electrodes;a frequency setting section adapted for setting a predetermined frequency as a frequency of the alternating current impressed by the alternating current applying section; anda voltage measuring section adapted for measuring a voltage at the time of impressing the alternating current of the predetermined frequency,wherein the obtaining section obtains either of the voltage measured by the voltage measuring section and the bioelectrical impedance as the information ...

Tissue indicator determination

A method for use in analysing impedance measurements performed on a subject, the method including, in a processing system, determining at least one impedance value at at least one frequency, the at least one impedance value representing the impedance of a segment of the subject, determining a tissue impedance parameter value using the at least one impedance value and determining a tissue indicator based at least in part on the tissue impedance parameter value.

Enhanced medical device for use in bodily cavities, for example an atrium

Systems, methods, and devices allow intravascular or percutaneous mapping, orientation and/or ablation, in bodily cavities or lumens. A device includes elongate members, moveable between an unexpanded configuration and an expanded or fanned configuration. The elongate members form a stack in the unexpanded configuration to fit through a catheter sheath. The elongate members follow respective arcuate or curvilinear paths as advanced from the sheath into the bent or coiled stack configuration, adopting volute, scroll or rho shapes, and may be nested. The elongated members are fanned or radially spaced circumferentially with respect to one another into the expanded or fanned configuration. Transducer elements carried by elongate members sense various physiological characteristics of or proximate tissue, and/or may apply energy to or proximate tissue. The elongate members are rotatable in groups or as a group in the expanded configuration. The device is retractable.

SINGLE INJECTION METHODS FOR OBTAINING CONDUCTANCE MEASUREMENTS WITHIN LUMINAL ORGANS USING IMPEDANCE DEVICES

Single injection methods for obtaining conductance measurements within luminal organs using impedance devices. In at least one method embodiment, the method is performed by introducing at least part of an impedance device into a mammalian luminal organ, the impedance device comprising an elongated body and a detector positioned along the elongated body, obtaining conductance measurements indicative of a fluid native to the mammalian luminal organ and indicative of a fluid injection while the detector is present within and outside of the lumen of the outer sheath, and calculating a size parameter of the mammalian luminal organ based in part upon some of the obtained conductance measurements. 1. A method for obtaining one or more conductance measurements using an impedance device , the method comprising the steps of:introducing at least part of an impedance device into a mammalian luminal organ, the impedance device comprising an elongated body and a detector positioned along the elongated body;obtaining a first conductance measurement using the detector while the detector is surrounded by an outer sheath surrounding at least part of the impedance device, the first conductance measurement indicative of a fluid native to the mammalian luminal organ present within a lumen of the outer sheath;obtaining a second conductance measurement using the detector while the detector is surrounded by the outer sheath, the second conductance measurement indicative of a first injection of a first solution of a first compound through the lumen of the outer sheath;moving the impedance device and/or the outer sheath relative to one another so that the outer sheath no longer surrounds the detector;obtaining a third conductance measurement using the detector, the third conductance measurement indicative of the fluid native to the mammalian luminal organ;obtaining a fourth conductance measurement using the detector, the fourth conductance measurement indicative of a second injection of the ...

Breast classification based on impedance measurements

A method of screening for breast cancer, including determining at least one first electrical impedance related characteristic for a first breast of a patient, determining at least one second electrical impedance related characteristic for a second breast of a patient and classifying the patient as requiring additional testing, responsive to the value of the first and second characteristics, wherein classifying is not based on a difference between the first and second characteristics.

VOLUMETRIC INDUCTION PHASE SHIFT DETECTION SYSTEM FOR DETERMINING TISSUE WATER CONTENT PROPERTIES

A method and apparatus of determining the condition of a bulk tissue sample, by: positioning a bulk tissue sample between a pair of induction coils (or antennae); passing a spectrum of alternating current (or voltage) through a first of the induction coils (or antennae); measuring spectrum of alternating current (or voltage) produced in the second of the induction coils (or antennae); and comparing the phase shift between the spectrum of alternating currents (or voltages) in the first and second induction coils (or antennae), thereby determining the condition of the bulk tissue sample. 1. A method of determining the condition of a bulk tissue sample , comprising:positioning a bulk tissue sample between a pair of induction coils or antennae;passing a spectrum of alternating current or voltage through a first of the induction coils or antennae;measuring a spectrum of alternating current or voltage produced in the second of the induction coils or antennae; andcomparing the phase shift between the spectrum of alternating currents or voltages in the first and second induction coils or antennae, thereby determining the condition of the bulk tissue sample.2. The method of claim 1 , wherein the first and second induction coils or antennae do not contact the bulk tissue sample.3. The method of claim 1 , wherein determining the condition of the bulk tissue sample comprises:detecting at least one condition from the group consisting of edema, ischemia, bleeding, dehydration, water accumulation in the bulk tissue sample, extravasation, and disease.4. The method of claim 1 , wherein the bulk tissue sample is selected from the group consisting of brain tissue claim 1 , lung tissue claim 1 , heart tissue claim 1 , muscle tissue claim 1 , skin tissue claim 1 , kidney tissue claim 1 , cornea tissue claim 1 , liver tissue claim 1 , abdomen tissue claim 1 , head tissue claim 1 , leg tissue claim 1 , arm tissue claim 1 , pelvis tissue claim 1 , chest tissue or trunk tissue.56-. ( ...

Body fat measurement device

A body fat measurement device includes a back area electrode group support unit including back area electrodes arranged to contact a back area of a measurement subject, a trunk area dimension measurement unit that detects the width and depth of a trunk area of the measurement subject, a position detection unit that detects a relative positional relationship between the back area electrode group support unit and the trunk area dimension measurement unit, an electrode selection unit that selects specific electrodes, placed in contact with the back area at an area that corresponds to the location of the navel of the measurement subject, from a plurality of electrodes included in a trunk area electrode group, based on the position information detected by the position detection unit, and a body impedance measurement unit that measures a body impedance of the measurement subject using the selected back area electrodes.

Method and Device for Evaluation of Local Tissue's Biological or Biomechanical Character

A device for evaluation of a tissue's biological or biomechanical character is disclosed. The device uses negative pressure to draw a portion of the tissue across one or more electrode pairs disposed within the device. By measuring one or more parameters associated with an electric or magnetic field defined by the electrode pairs, in vivo evaluation of the tissue's biological or biomechanical character may be achieved in a minimally invasive manner. The device may also include an indenter to apply a positive stress on the tissue within the sidewall to further evaluate its biological or biomechanical character. A method of using the device is also disclosed.

Implantable Dielectrometer

Diagnostic apparatus () includes a sealed case (), comprising a biocompatible material and configured for implantation within a body of a human subject (). A dielectrometric probe () is connected to the case and includes first and second conductors (), which are configured to be placed in proximity to a target tissue () in the body. A driving circuit (), which is contained in the case, is coupled to apply a radio-frequency (RF) signal to the probe and to sense the signal returned from the probe. Processing circuitry () is configured to evaluate, responsively to the returned signal, a dielectric property of the target tissue. 1. Diagnostic apparatus , comprising:a sealed case, comprising a biocompatible material and configured for implantation within a body of a human subject;a dielectrometric probe, which is connected to the case and comprises first and second conductors, which are configured to be placed in proximity to a target tissue in the body;a driving circuit, which is contained in the case and is coupled to apply a radio-frequency (RF) signal to the probe and to sense the signal returned from the probe; andprocessing circuitry, which is configured to evaluate, responsively to the returned signal, a dielectric property of the target tissue.2. The apparatus according to claim 1 , wherein the driving circuit is configured to apply the RF signal to the probe and to sense the returned signal at multiple different frequencies.3. The apparatus according to claim 1 , wherein the dielectric property evaluated by the processing circuitry comprises a complex permittivity of the target tissue.4. The apparatus according to claim 3 , wherein the processing circuitry is configured to evaluate the complex permittivity by measuring an impedance between the first and second conductors.5. The apparatus according to claim 3 , wherein the processing circuitry is configured to evaluate the complex permittivity by measuring a reflection of the signal from the probe claim 3 , which ...

DRY WEIGHT PREDICTOR

Methods and apparatus for predicting/estimating the dry weight of an individual, e.g., a patient undergoing dialysis treatment, are provided. The techniques employ a bioimpedance measurement () on the individual's calf () to obtain information regarding the extracellular fluid volume of the calf. Using a measurement of the calf's circumference (), a resistivity value is calculated, normalized by the individual's body mass index (BMI), and then offset by a reference value to obtain a new variable, ΔnRho, which is shown, by comparison with a “gold standard” (FIGS. -), to be highly effective in predicting/estimating dry weight (FIGS. - and -). The techniques are easy to use and provide accurate dry weight predictions/estimations without substantially adding to the complexity or cost of dialysis procedures. The techniques can also be used for individuals who are not renal patients, e.g., patients suffering from other diseases in which fluid overload can occur, athletes, fitness enthusiasts, and the like. 1. A method of predicting/estimating an individual's dry weight , said individual having a BMI value , comprising:(a) obtaining a measured value indicative of the extracellular fluid volume of the individual's calf using a bioimpedance measurement technique;(b) obtaining a measured value indicative of the circumferential size C of the individual's calf;(c) determining a normalized value indicative of the extracellular fluid volume of the individual's calf from the measured values of steps (a) and (b) and the individual's BMI value;(d) determining a difference value between the normalized value of step (c) and a reference value for the normalized value; and(e) using the difference value of step (d) to determine a predicted/estimated value for the individual's dry weight.26-. (canceled)7. The method of wherein the reference value used in step (d) is obtained by performing steps (a) through (c) on at least one set of reference individuals.8. The method of wherein the ...

METHOD AND SYSTEM FOR IDENTIFYING A LOCATION FOR NERVE STIMULATION

A system and method for identifying a stimulation location on a nerve is disclosed. The system includes an image-based navigation interface used to facilitate advancing a stimulation element within a patient body toward a target nerve stimulation site. Using the system one determines, separately for each potential target nerve stimulation site, a neuromuscular response of muscles produced upon applying a stimulation signal at the respective separate potential target stimulation sites. The image-based navigation interface is configured to display a graphic identification of which muscles were activated for each respective potential target nerve stimulation site upon applying the stimulation signal. 191-. (canceled)92. A system for placing a stimulation element , the system comprising: a stimulation engine configured to apply an electrical stimulation signal to a patient body portion via a stimulation element; and', 'a muscle response module configured to determine a response of a muscle to application of the stimulation signal;, 'a neuromuscular response evaluation module includinga probe interface including an array of ports;an array of sensor probes, each removably connectable to a respective one of the ports and removably attachable to a body portion corresponding to the muscle, the sensor probe configured to sense the muscle response; and an image display module configured to display at least one image of the patient body portion; and', 'a muscle identifier module configured to visually identify, superimposed on the at least one image, which muscles were activated for each respective application of the stimulation signal., 'a graphical user interface including93. The system of claim 92 , wherein the muscle response module comprises: an electromyography circuitry configured to determine the muscle response via electromyography; and', 'a compound muscle action potential module configured to determine the muscle response via observing a compound muscle action ...

MEDICAL DEVICE SYSTEM

The invention provides a medical device system comprising at least two technologies wherein at least one technology is based on bio-impedance measuring and/or at least one technology is based on spectrophotometry measurements wherein software cross analyses the results to assess the homeostasis of an individual. The technologies measure a variety of parameters. In one embodiment the bioimpedance measuring equipment measures in bipolar mode and in tetrapolar mode and the spectophotmeter measuring equipment comprises a pulse oximeter. The system and homeostasis score can be used to determine and monitor therapy for a patient. 1. A medical device system comprising at least two technologies wherein at least one technology is based on bio-impedance measuring and/or at least one technology is based on spectrophotometry measurements wherein software cross analyses the results to assess the homeostasis of an individual.2. A system as claimed in wherein a series of medical devices measure a variety of parameters using different technologies and software compiles the results of these to provide a homeostasis score.3. A system as claimed in comprising at least a pulse oximeter which provides a vascular waveform in combination with other biosensors and software.4. A system as claimed in which further includes EKG monitor claim 1 , blood glucose meter claim 1 , spirometer.5. A system as claimed in comprising at least 4 biosensors wherein signal processing-analysis is managed by software.6. A system as claimed in wherein the technologies include a) bioimpedance in bipolar mode (ElS sensor) claim 5 , b) bioimpedance in tetrapolar mode (ES-BC sensor) claim 5 , c) a spectrophotometer (ESO sensor) and d) oscillometric measurements. (NlBP sensor)7. Use of a system as claimed in to establish a homeostasis score for a patient.8. A medical device system to assess the homeostasis of an individual claim 1 , the system comprising bio impedance measuring equipment and spectophometry ...