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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 2089. Отображено 100.
03-05-2012 дата публикации

Reactance changes to identify and evaluate cryo ablation lesions

Номер: US20120109115A1
Автор: Catherine R. Condie, Kathryn Elaine Kasischke, Marshall L. Sherman
Принадлежит: MEDTRONIC ABLATION FRONTIERS LLC

A method of assessing lesion quality of an ablated tissue region comprising ablating at least a portion of the tissue region. The reactance of the ablated tissue region is measured. The lesion quality of the ablated tissue region is determined based on the measured reactance.

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Номер записи: 1
08-11-2012 дата публикации

Ablation devices and methods of use

Номер: US20120283716A1
Автор: Robert F. Bencini
Принадлежит: Boston Scientific Scimed Inc

Described herein are various methods and devices for delivering cryoablative therapy. One such device includes a cryoablation chamber and a volume displacement chamber. In use, the volume displacement chamber can be expanded to occupy a non-therapeutic volume.

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Номер записи: 2
25-04-2013 дата публикации

Cryosurgical system

Номер: US20130103020A1
Автор: Alexander Levin
Принадлежит: Individual

An invention relates to the area of cryosurgical equipment. It proposes a cryosurgical system, which incorporates measuring and computing means for estimation of a real time ice ball diameter and operation temperature of a cryotip (the distal section of a cryosurgical probe). The cryosurgical probe of the cryosurgical system operates by blowing in a gaseous medium at cryogenic temperature.

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Номер записи: 3
02-05-2013 дата публикации

Cryogenic balloon device with radiofrequency tip

Номер: US20130110098A1
Автор: Jean-Pierre Lalonde
Принадлежит: MEDTRONIC CRYOCATH LP

An intravascular ablation device, including a flexible elongate body; an expandable element positioned on the elongate body; a radiofrequency or electroporation treatment segment located distally of the expandable element; a cryogenic coolant source in fluid communication with an interior of the expandable element; and a radiofrequency or electroporation energy source in communication with the radiofrequency or electroporation treatment segment.

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Номер записи: 4
07-11-2013 дата публикации

Delivery devices with coolable energy emitting assemblies

Номер: US20130296647A1
Автор: Martin L. Mayse, Steven C. Dimmer
Принадлежит: Holaira Inc

Systems, delivery devices, and methods to treat to ablate, damage, or otherwise affect tissue. The treatment systems are capable of delivering a coolable ablation assembly that ablates targeted tissue without damaging non-targeted tissue. The coolable ablation assembly damages nerve tissue to temporarily or permanently decrease nervous system input.

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Номер записи: 5
27-02-2014 дата публикации

Cryo-ablation refrigerant distribution catheter

Номер: US20140058369A1
Автор: Raphael Hon
Принадлежит: Boston Scientific Scimed Inc

Described herein are methods and devices for performing ablation via a cryoablation catheter. An ablation catheter having a cyroablation chamber at its distal end can be used to achieve a uniform ablation band in or around the pulmonary veins. The cyrochamber can house a dispersion member in fluid communication with a refrigerant supply and can function to evenly distribute received refrigerant over some portion of the inner wall of the cryochamber. As a result of this even distribution of refrigerant within the cyrochamber, uniform ablation of the targeted tissue of the patient can be achieved.

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Номер записи: 6
27-02-2014 дата публикации

Cryosurgical probe with adjustable sliding apparatus

Номер: US20140058370A1
Автор: Jay J. Eum, Thach Duong
Принадлежит: Endocare Inc

A cryosurgical probe assembly including a cryosurgical probe having a shaft, an insulation element housed within the cryosurgical probe and being slideably repositionable relative to the shaft, and a fluid supply line having an inlet portion for connection to a cryogenic fluid source.

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Номер записи: 7
06-01-2022 дата публикации

Cryosurgical Probe with Enhanced Thermal Performance

Номер: US20220000532A1
Автор: Grimm Daniel N.
Принадлежит:

A probe and method of using a probe are disclosed. The probe may comprise a first member, a tip, a second member, and a third member. The first member may have a first and second end portions. The tip may be configured to engaged to the first member at the second end portion. The second member may be configured to extend and be positioned within the first member. The third member may be configured to be disposed outward of the second member along at least a portion of the second member, engage an inner surface of the first member, and define to least one passage between the third member and the first member. The probe may be coupled to a fluid supply and return, and fluid may flow within the probe, including within the passage defined between the first and third members. 1. A probe , comprising:a first member having a first end portion and a second end portion;a tip configured to be coupled to the first member at the second end portion;a second member configured to be positioned within the first member such that the second member extends within the first member; anda third member configured to be disposed outward from the second member along at least a portion of the second member, wherein the third member is configured to operably engage an inner surface of the first member to define at least one passage between the third member and the first member, and wherein a portion of the third member is configured to substantially enclose at least a portion of the second member.2. The probe of claim 1 , wherein the second member and third member are configured to be positioned within the first member such that a distal end of the second member and the distal end of the third member are positioned within a common plane.3. The probe of claim 1 , wherein the second member and third member are configured to be positioned within the first member such that a first distance between a distal end of the second member and the tip is less than a second distance between the distal end ...

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Номер записи: 8
07-01-2021 дата публикации

Direct Vision Cryosurgical Probe and Methods of Use

Номер: US20210000331A1
Автор: Matthew Herron, Richard C. Ewers, Vahid Saadat
Принадлежит: Arrinex Inc

A direct vision cryosurgical and methods of use are described herein where the device may generally comprise an elongated rigid structure with a distal end, a proximal end, and a central lumen. The distal end may comprise a non-coring optically transparent needle tip with at least one lateral fenestration in communication with the central lumen. The distal end may also house at least one imaging device configured for distal imaging. A proximal end of the device may comprise a handle with a means for connecting the imaging device(s) to an imaging display(s), and a means for accessing bodily tissue in the vicinity of the distal end with a cryo-ablation probe through the central lumen and the lateral fenestration(s) for diagnostic or therapeutic purposes.

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Номер записи: 9
07-01-2021 дата публикации

Catheter system for cryoablation of the vagus nerve

Номер: US20210000520A1
Автор: Georg Daniel Andreas Nollert
Принадлежит: Individual

A catheter system for cryoablation of the stomach, comprising: a catheter and at least one inflatable cryoballoon which is fastened to the catheter and exhibits a contact curve along which the cryoballoon can be brought into contact with the fundus, wherein the contact curve is a closed curve on the surface of the cryoballoon, and the cryoballoon contains a first cooling arrangement which extends along less than three quarters of the length of the contact curve.

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Номер записи: 10
07-01-2021 дата публикации

DEVICES, SYSTEMS, AND METHODS FOR CRYOGENIC BIOPSY SAMPLING

Номер: US20210000521A1
Автор: Dong Jing, Ferrokhi Hamid, Otuya David, Tearney Guillermo J., Verma Yogesh
Принадлежит:

In some embodiments, devices, systems, and methods for cryogenic biopsy sampling are provided. In some embodiments, a device for cryogenic biopsy sampling is provided, the device including: a dual lumen tube; an elongated probe tip coupled to the distal end of the dual lumen tube, with a first lumen extending into a hollow portion in the tip and a second lumen in fluid communication with the hollow portion; a first port in fluid communication with the first lumen; a second port in fluid communication with the second lumen, wherein the first lumen, the elongated probe element, and the second lumen provide a closed pathway through which a substance introduced through the first port can flow through the first lumen into the elongated probe element, and out of the elongated probe element through the second lumen to the second port. 1. A device for cryogenic biopsy sampling , comprising:a dual lumen tube having a proximal end and a distal end; a first lumen of the dual lumen tube extending into a hollow portion of the elongated probe element, and', 'a second lumen of the dual lumen tube being in fluid communication with the hollow portion;, 'an elongated probe element coupled to the distal end of the dual lumen tube,'}a housing coupled to the proximal end of the dual lumen tube;a first port coupled to the housing and in fluid communication with the first lumen; and 'the first lumen, the elongated probe element, and the second lumen providing a closed pathway through which a substance introduced through the first port flows through the first lumen into the elongated probe element and out of the elongated probe element through the second lumen to the second port.', 'a second port coupled to the housing and in fluid communication with the second lumen,'}2. The device for cryogenic biopsy sampling of claim 1 , wherein the elongated probe element comprises aluminum.3. The device for cryogenic biopsy sampling of claim 1 , wherein at least a portion of the inner surface of the ...

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Номер записи: 11
05-01-2017 дата публикации

N2O LIQUEFACTION SYSTEM WITH SUBCOOLING HEAT EXCHANGER FOR MEDICAL DEVICE

Номер: US20170000544A1
Автор: MAHROUCHE Rachid, MONGER Eric, TZONEV Vladimir
Принадлежит:

A system and kit for using a source of low-pressure refrigerant for a cryotherapy procedure and for subcooling a cryotherapy refrigerant. The system may generally include a fluid reservoir and a fluid flow path in thermal exchange with the fluid reservoir, the fluid flow path including a first thermal exchange device in thermal exchange with the fluid reservoir, a compressor in fluid communication with the first thermal exchange device, a condenser, a reversing valve located between the compressor and the condenser, a second thermal exchange device located between the reversing valve and the compressor, and an expansion valve located between the condenser and the thermal exchange device. The third thermal exchange device may be configured to be in fluid communication with the cryotherapy console and configured to place a secondary refrigerant within the first fluid flow path in thermal communication with a secondary refrigerant of the cryotherapy system. 1. A kit for use with a source of low-pressure refrigerant , the kit comprising:a fluid reservoir; and a first thermal exchange device in thermal exchange with and fluidly isolated from the fluid reservoir;', 'a compressor in fluid communication with the first thermal exchange device;', 'a condenser;', 'a reversing valve located between the compressor and the condenser; and', 'a second thermal exchange device located between the reversing valve and the compressor., 'a closed-loop fluid flow path in thermal exchange with the fluid reservoir, the closed-loop fluid flow path including2. The kit of claim 1 , wherein the second thermal exchange device is configured to be in fluid communication with a cryotherapy console.3. The kit of claim 1 , wherein the fluid flow path is a first fluid flow path claim 1 , the kit further including a second fluid flow path that is fluidly isolated from the first fluid flow path claim 1 , the fluid reservoir being included in the second fluid flow path.4. The kit of claim 3 , wherein the ...

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Номер записи: 12
03-01-2019 дата публикации

TREATMENT SYSTEMS FOR REMOVING HEAT FROM SUBCUTANEOUS LIPID-RICH CELLS

Номер: US20190000663A1
Автор: Anderson Richard Rox, Manstein Dieter
Принадлежит:

The present invention relates to methods for use in the selective disruption of lipid-rich cells by controlled cooling. The present invention further relates to a device for use in carrying out the methods for selective disruption of lipid-rich cells by controlled cooling. 1. A system for removing heat from subcutaneous lipid-rich cells of a region of a subject , the system comprising a treatment system including at least one cooling/heating element and configured to wrap around at least a portion of the subject such that the system is capable of reducing a temperature of the region to damage the subcutaneous lipid-rich cells while not injuring non-lipid-rich cells proximate to the at least one cooling/heating element.2. The system of wherein the treatment system is configured to at least partially surround one or more selected from the group consisting of: an arm claim 1 , an upper or lower leg claim 1 , and a waist of the subject.3. The system of wherein the treatment system is configured to form a band or cylinder around the portion of the subject.4. The system of wherein the portion of the subject includes one or more selected from the group consisting of: an arm claim 1 , an upper or lower leg claim 1 , and a waist of the subject.5. The system of wherein the treatment system comprises a flexible material that allows the treatment system to wrap around the portion of the subject.6. The system of wherein the treatment system includes a fastening mechanism that couples together ends of the treatment system.7. The system of wherein the at least one cooling/heating element includes a plurality of cooling/heating elements arranged circumferentially about the portion of the subject when the treatment system wraps around the portion of the subject.8. The system of wherein the treatment system includes at least one passage through which a fluid is capable of flowing to change the temperature of the subcutaneous lipid-rich cells.9. The system of wherein the fluid ...

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Номер записи: 13
13-01-2022 дата публикации

Balloon catheter and electrophysiological system

Номер: US20220008111A1
Автор: BO Liang, Jiaqiang JIANG, Qiancheng ZHAO, Yiyong Sun, Yunzhu XI
Принадлежит: Shanghai Microport EP MedTech Co Ltd

A balloon catheter (100) and an electrophysiological system, which aim to improve the operability of accurately monitoring the balloon surface temperature at the surface of a double-layered balloon (110). The balloon catheter (100) comprises a catheter body (130), a double-layered balloon (110), at least one temperature measuring element (120), and at least one adhesion piece (140); the temperature measuring element (120) is disposed in an interlayer (113) formed by an inner layer balloon (112) and an outer layer balloon (111); the adhesion piece (140) is adheringly connected to the temperature measuring element (120), and is simultaneously adheringly connected to the inner layer balloon (112) or the outer layer balloon (111); the temperature measuring element (120) is attached to the inner layer balloon (112) or the outer layer balloon (111) by means of the adhesion piece (140); when the double-layered balloon (110) is deformed, the adhesion piece (140) may be displaced relative to the inner layer balloon (112) or outer layer balloon (111) connected to the adhesion piece (140), which enables the temperature measuring element (120) to be displaced relative to the inner layer balloon (112) or outer layer balloon (111) connected to the adhesion piece (140).

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Номер записи: 14
20-01-2022 дата публикации

High-Temperature Cryosurgery System and Methods of Using the Same

Номер: US20220015816A1
Автор: Barken Israel
Принадлежит:

A high temperature cryosurgery system and method of operation comprising a refrigeration assembly, a cryoprobe and a refrigerant wherein the cryoprobe and the refrigeration assembly are fluidly coupled in a closed loop configured to cycle the refrigerant in a fluid state from the refrigeration assembly to the cryoprobe and further configured to cycle the refrigerant in a vapor state from the cryoprobe to the refrigeration assembly. A method for treating cancer tumors and metastatic cancer cells by disrupting the tumor by sequentially or concurrently administering an ablative energy in combination with immunomodulation and/or pharmacological application, in one or more cycles, where the physical disruption is applied at levels sufficient to create the abscopal effect. That effect is generated by stimulating the immune cells in the microenvironment. The tumor is treated in a way permitting the remaining cells or elements in the tumor microenvironment to exert net immune stimulation with also long-term memory cells to fight subsequent appearing tumor in the future. Adding immune modulators injected in situ systemically or embedded in slow releasing means locally or systemically will boost the immune response to the cancer. 1. A cryosurgery system comprising:a. a refrigeration assembly;b. an operator probe having a housing, a fluid chamber, a fluid inlet communicating with the fluid chamber, a vapor chamber; a fluid outlet communicating with the vapor chamber; a fluid conduit in communication with the fluid inlet and a vapor conduit in communication with the vapor outlet;c. a cryoneedle operably coupled to the housing of the operator probe and in communication with the fluid inlet and the vapor chamber of the operator probe;d. a refrigerant contained within the fluid chamber, the vapor chamber, the fluid conduit and the vapor conduit; andwherein the operator probe and the refrigeration assembly are fluidly coupled in a closed loop configured to cycle the refrigerant in ...

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Номер записи: 15
12-01-2017 дата публикации

Treatment systems and methods for affecting glands and other targeted structures

Номер: US20170007309A1
Автор: Bryan J. Weber, George Frangineas, Jr., Gurvinder Singh Nanda, Kerrie Jiang, Kristine Tatsutani, Leonard DeBenedictis, Linda PHAM, Peter Yee
Принадлежит: Zeltiq Aesthetics Inc

Treatment systems, methods, and apparatuses for treating acne, hyperhidrosis, and other skin conditions are described. Aspects of the technology can include cooling a surface of a patient's skin and detecting changes in the tissue. The tissue can be cooled a sufficient length of time and to a temperature low enough to affect glands or other targeted structures in the skin.

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Номер записи: 16
10-01-2019 дата публикации

FEEDBACK SYSTEM FOR CRYOABLATION OF CARDIAC TISSUE

Номер: US20190008572A1
Автор: BISCHOF John C., GROVES Regina E., Iaizzo Paul A., LALONDE Jean-Pierre, LASKE Timothy G.
Принадлежит:

A method and system for providing lesion depth feedback during an ablation procedure. In particular, the method and system provide feedback data or information relating to lesion depth in myocardial tissue during a cryoablation procedure. A plurality of tissue temperature measurements may be transmitted from a plurality of thermocouples disposed on a cryotreatment element, which measurements may be used to determine a slope of change in temperature sensed by each thermocouple over time. The circulation of coolant through the treatment element may be adjusted when the slope changes. A change in slope may indicate that the cryoablation temperatures have passed through target myocardial tissue into non-target, non-myocardial tissue, which may result in collateral damage to structures near the heart. 1. A method for assessment of ablation lesion depth in myocardial tissue , the method comprising:taking a plurality of temperature measurements with one or more thermocouples;determining a rate of change in temperature for each of the one or more thermocouples; andadjusting a temperature of a treatment element in contact with the myocardial tissue when the rate of change in temperature changes.2. The method of claim 1 , wherein the temperature of the treatment element is adjusted when the rate of change in temperature increases negatively.3. The method of claim 1 , wherein the temperature of the treatment element is adjusted when the rate of change in temperature decreases.4. The method of claim 2 , wherein the treatment element is a cryoballoon claim 2 , and the one or more thermocouples are disposed on the cryoballoon.5. The method of claim 4 , wherein the cryoballoon is in fluid communication with a coolant supply reservoir.6. The method of claim 5 , wherein adjusting the temperature of the treatment element includes adjusting a flow of coolant within the cryoballoon.7. The method of claim 6 , wherein adjusting the flow of coolant includes at least one of stopping and ...

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Номер записи: 17
19-01-2017 дата публикации

Cryogenic Cylinder

Номер: US20170014174A1
Автор: Kayali Walid, Levine Lewis, Schomacker Kevin, TOMASETTI Perry
Принадлежит:

A cryogenic cylinder including authenticating features and an apparatus recognizing the features and facilitation the cylinder use. The authenticating features prevent use of an unauthorized cryogenic cylinders. The cylinder also includes a number of mechanical features preventing repeat filling of the cylinder by cryogenic fluid or reuse of the cylinder once empty. 1. A cryogenic liquid storing cylinder comprising:a liquid containing body configured to contain a liquid under pressure;a fitting configured to include a single use fitting valve facilitating inlet of the liquid into the liquid containing body of the cylinder;wherein the single use fitting valve is also configured to facilitate dispensing the liquid from the liquid containing body of a liquid storing cylinder; andwherein the single use fitting valve is configured to be destroyed upon depletion of the liquid in the cylinder.2. The liquid storing cylinder according to wherein the single use fitting valve falls inside the container upon depletion of the liquid in the container.3. The liquid storing cylinder according to wherein the cylinder further includes a pressure relief valve; and wherein the pressure relief valve operates on a gaseous aggregate state of the liquid.4. The liquid storing cylinder according to wherein the cylinder includes at least one cylinder authenticating feature associated with the cylinder.5. The liquid storing cylinder according to further comprising an electronic module located at inlet of the liquid into the container.6. The liquid storing cylinder according to further comprising an electronic module located in the fitting valve facilitating inlet of the liquid into the liquid containing body of the cylinder.7. The liquid storing cylinder according to wherein the fitting valve includes at least one of a group of authentication features consisting of a mechanical feature claim 1 , electronic circuit claim 1 , readable information and a combination of the above.8. An apparatus ...

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Номер записи: 18
21-01-2016 дата публикации

CARDIAC CRYOLIPOLYSIS FOR THE TREATMENT OF CARDIAC ARRHYTHMIA

Номер: US20160015444A1
Автор: WITTENBERGER Dan
Принадлежит:

A system, device, and method for the treatment of cardiac arrhythmia by, specifically, cryolipolysis of non-myocardial tissue and cryoablation of myocardial tissue. A system for treating cardiac arrhythmia may include a first thermal treatment device configured for placement within a heart in contact with myocardial tissue, a second thermal treatment device configured for placement in contact with pericardial tissue, an ablation energy source in communication with the first thermal treatment device, and a cooling energy source in communication with the second thermal treatment device, the cooling energy source causing the second thermal treatment device to reach a temperature insufficient for myocardial ablation when the second thermal treatment device is activated. A method of treating cardiac arrhythmia may include introducing a cooling element into a pericardial space proximate pericardial adipose tissue, and activating the cooling element to reduce the temperature of adjacent pericardial adipose tissue to approximately 0° C.

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Номер записи: 19
16-01-2020 дата публикации

Bounded electrosurgical energy systems and methods employing zone-based energy

Номер: US20200015878A1
Автор: William S. Krimsky
Принадлежит: COVIDIEN LP

A method of treating tissue is provided herein. The method comprises positioning an end effector in a first position in proximity to tissue, wherein the end effector has one or more first thermal elements and one or more second thermal elements and an energy delivery configuration, activating the one or more first thermal elements, absorbing energy from tissue via the one or more first thermal elements, wherein the energy absorbed is in a first predetermined volume based on the energy delivery configuration, activating the one or more second thermal elements, delivering energy to tissue via the one or more second thermal elements, wherein the energy delivered is in a second predetermined volume based on the energy delivery configuration, and generating a predetermined treatment zone based on the first predetermined volume and the second predetermined volume.

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Номер записи: 20
15-01-2015 дата публикации

REGULATING PRESSURE TO LOWER TEMPERATURE IN A CYROTHERAPY BALLOON CATHETER

Номер: US20150018811A1
Автор: GEORGE LEONARD J., HEBERER JOANN
Принадлежит:

A cryotherapy catheter can include an elongate member and an inflatable balloon at a distal end of the elongate member, the elongate member having lumens formed therein to supply cryogenic fluid to a chamber of the balloon and to channel exhaust from the balloon chamber; and a controller programmed to control a first rate at which the cryogenic fluid is supplied to the balloon chamber and a second rate at which exhaust is channeled from the balloon chamber, wherein the controller is programmed to a) develop, during a first phase of a cryotherapy procedure, a first pressure inside the balloon chamber at a value that is greater than an ambient pressure outside and adjacent to a proximal end of the elongate member, and b) develop, during a second phase of the cryotherapy procedure, the first pressure at a value that is less than the ambient pressure. 1. A method of operating a cryotherapy balloon catheter , the method comprising:introducing a cryotherapy balloon catheter to a treatment site inside a patient's body, the cryotherapy balloon catheter including an inflatable balloon at a distal end of an elongate member, the elongate member having lumens therein configured to supply cryogenic fluid to the balloon;regulating a flow of cryogenic fluid into and exhaust from the balloon to create a first pressure and first temperature inside the balloon, thereby pressing an outer wall of the balloon against body tissue at the treatment site and freezing the body tissue to the outer wall; andthereafter, regulating the flow of cryogenic fluid into and exhaust from the balloon to create a second pressure and second temperature inside the balloon, wherein the second pressure is less than the first pressure and the second temperature is below the first temperature.2. The method of claim 1 , wherein the cryotherapy balloon catheter is configured to enable Joule-Thomson cooling inside the balloon.3. The method of claim 1 , wherein the first pressure is approximately five pounds per ...

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Номер записи: 21
10-02-2022 дата публикации

CRYOGENIC SURGICAL SYSTEMS

Номер: US20220039852A1
Автор: Fago Frank M., McHale Jonathon, Stefanov Stefan
Принадлежит: AtriCure, Inc.

Medical devices and related methods, and, more specifically, cryogenic surgical systems and related methods are disclosed. Some example cryogenic surgical systems may include a cryosurgical control unit configured to cool a cryosurgical probe to a temperature colder than a temperature at which flow of cryogenic fluid to the probe is stopped. Some example tank level indicating systems may utilize the pressure of the fluid in the tank and a temperature of the exterior wall of the tank to indicate liquid level. 114.-. (canceled)15. A system configured to display an indicium associated with a liquid level in a tank , the tank containing liquid and gas phases of a fluid , the system comprising:a heater thermally coupled to an exterior wall of the tank;a pressure sensor arranged to measure a pressure of the fluid in the tank;a temperature sensor arranged to measure a temperature of the exterior wall of the tank; andan indicator capable of displaying an indicium associated with a first discrete liquid level, an indicium associated with a second discrete liquid level, and an indicium associated with a third discrete liquid level, the first discrete liquid level corresponding to a relatively higher liquid level in the tank, the second discrete liquid level corresponding to an intermediate liquid level in the tank, and the third discrete liquid level corresponding to a relatively lower liquid level in the tank; [ '(A) (1) the pressure of the fluid in the tank is greater than a first threshold pressure and (2) the temperature of the exterior wall is less than a first threshold temperature;', '(I) displaying an indicium associated with a first discrete liquid level if'}, '(A) (1) the pressure of the fluid in the tank is the pressure of the fluid in the tank is greater than a second threshold pressure and (2) the temperature of the exterior wall is less than a second threshold temperature; and', '(II) displaying an indicium associated with a second discrete liquid level if'}, '( ...

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Номер записи: 22
23-01-2020 дата публикации

CRYOGENIC SURGICAL SYSTEMS

Номер: US20200022745A1
Автор: Fago Frank M., McHale Jonathon, Stefanov Stefan
Принадлежит: AtriCure, Inc.

Medical devices and related methods, and, more specifically, cryogenic surgical systems and related methods are disclosed. Some example cryogenic surgical systems may include a cryosurgical control unit configured to cool a cryosurgical probe to a temperature colder than a temperature at which flow of cryogenic fluid to the probe is stopped. Some example tank level indicating systems may utilize the pressure of the fluid in the tank and a temperature of the exterior wall of the tank to indicate liquid level. 1. A cryogenic surgical system , comprising:a cryosurgical probe fluidicly interposing an inlet conduit arranged to supply a cryogenic fluid to the cryosurgical probe and an exhaust conduit arranged to direct the cryogenic fluid away from the cryosurgical probe; anda cryosurgical control unit capable of receiving the cryogenic fluid from a cryogenic fluid source, the cryosurgical control unit comprising an inlet valve fluidicly coupled to the inlet conduit and configured to selectively supply the cryogenic fluid to the cryosurgical probe via the inlet conduit and an exhaust valve fluidicly coupled to the exhaust conduit and configured to selectively permit cryogenic fluid to flow from the exhaust conduit.wherein the cryosurgical control unit is configured to control cooling of the cryosurgical probe to a temperature lower than a first setpoint temperature by (1) cooling the cryosurgical probe by opening the inlet valve to supply the cryogenic fluid to the cryosurgical probe, (2) shutting the inlet valve when a temperature of the cryosurgical probe reaches the first setpoint temperature, (3) maintaining the inlet valve shut while the cryosurgical probe temperature is less than the first setpoint temperature.2. The system of claim 1 , wherein the cryosurgical control unit is configured to open the inlet valve to supply the cryogenic fluid to the cryosurgical probe when the temperature of the cryosurgical probe reaches a second setpoint temperature claim 1 , after ...

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Номер записи: 23
01-02-2018 дата публикации

REGULATING PRESSURE TO LOWER TEMPERATURE IN A CYROTHERAPY BALLOON CATHETER

Номер: US20180028251A1
Автор: GEORGE LEONARD J., HEBERER JOANN
Принадлежит: BOSTON SCIENTIFIC SCIMED, INC.

A cryotherapy catheter can include an elongate member and an inflatable balloon at a distal end of the elongate member, the elongate member having lumens formed therein to supply cryogenic fluid to a chamber of the balloon and to channel exhaust from the balloon chamber; and a controller programmed to control a first rate at which the cryogenic fluid is supplied to the balloon chamber and a second rate at which exhaust is channeled from the balloon chamber, wherein the controller is programmed to a) develop, during a first phase of a cryotherapy procedure, a first pressure inside the balloon chamber at a value that is greater than an ambient pressure outside and adjacent to a proximal end of the elongate member, and b) develop, during a second phase of the cryotherapy procedure, the first pressure at a value that is less than the ambient pressure. 1. A method of operating a cryotherapy balloon catheter , the method comprising:introducing a cryotherapy balloon catheter to a treatment site inside a patient's body, the cryotherapy balloon catheter including an inflatable balloon at a distal end of an elongate member, the elongate member having lumens therein configured to supply cryogenic fluid to the balloon;creating a first pressure with cryogenic fluid inside the balloon that is above ambient pressure, wherein ambient pressure comprises atmospheric air pressure adjacent to the patient's body, thereby freezing an outer wall of the balloon against body tissue at the treatment site; andthereafter, creating a second pressure inside the balloon, wherein the second pressure is equal to or negative relative to the ambient pressure and is sufficient to prevent the outer wall from being peeled away from the body tissue by vacuum forces inside the balloon or by elastic forces of material that makes up the balloon.2. The method of claim 1 , wherein the cryotherapy balloon catheter is configured to enable Joule-Thomson cooling inside the balloon.3. The method of claim 1 , ...

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Номер записи: 24
01-02-2018 дата публикации

CRYOGENIC BALLOON DEVICE WITH ELECTROPORATION TREATMENT REGION

Номер: US20180028252A1
Автор: LALONDE Jean-Pierre
Принадлежит:

An intravascular ablation device, including a flexible elongate body; an expandable element positioned on the elongate body; a radiofrequency or electroporation treatment segment located distally of the expandable element; a cryogenic coolant source in fluid communication with an interior of the expandable element; and a radiofrequency or electroporation energy source in communication with the radiofrequency or electroporation treatment segment. 1. A method of treating tissue , the method comprising: an elongate catheter body having a proximal portion and a distal portion;', 'an expandable first treatment region coupled to the distal portion of the elongate catheter body; and', 'a second treatment region coupled to the distal portion of the catheter body at a location that is distal to the cryogenic treatment region and defines an outer surface and a distal tip of the medical device;, 'positining a medical device proximate a first tissue area, the medical device includingactivating the expandable first treatment region to create a first treatment pattern in the first tissue area;deactivating the expandable first treatment region;repositioning the medical device such that the second treatment region is proximate a second tissue area; andactivating the second treatment region to treat a second treatment pattern in the second tissue area, the second treatment pattern being different than the first treatment pattern.2. The method of claim 1 , wherein the second treatment region is at least one of a radiofrequency treatment region and an electroporation treatment region.3. The method of claim 1 , wherein the second treatment region includes at least one electrode.4. The method of claim 3 , wherein the second treatment region is an electroporation treatment region.5. The method of claim 4 , further comprising a power source in communication with the at least one electrode and being configured to transmit electrical pulses claim 4 , activation of the second treatment ...

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Номер записи: 25
31-01-2019 дата публикации

SYSTEMS AND METHODS TO TREAT WOUNDS

Номер: US20190029745A1
Автор: OConnor John P.
Принадлежит:

The present disclosure relates generally to the field of cryoablation. In particular, the present disclosure relates to devices and methods for application of cryospray as a therapy to treat wounds.

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Номер записи: 26
31-01-2019 дата публикации

Method and Apparatus for Cryogenic Treatment of Skin Tissue

Номер: US20190029876A1
Автор: Anderson Richard Rox, Chan Henry Hin Lee, Manstein Dieter, Ting Joseph
Принадлежит:

Cosmetic method and apparatus are provided that can provide cooling and/or freezing of skin tissue proximal to the skin surface to generate an appearance of lightening or reduced pigmentation in the skin. The skin can be cooled to a temperature of less than about −5 degrees Celsius for a duration of about one minute or less, using a plurality of cooled contact surfaces, each having a width between about 2 mm and about 20 mm. A cooling arrangement can be provided to provide controlled heat removal from the skin tissue being treated. A sensor can optionally be provided to detect freezing of tissue proximal to the cooled surfaces. 131-. (canceled)32. A skin treatment device for freezing of a skin tissue , the skin treatment device comprising:a handle configured to facilitate handing and positioning of the skin treatment device; anda non-penetrating cooling portion defining a treatment area of the skin treatment device that is configured to contact a surface of the skin tissue, wherein a density of a cooling contact area is greater near a central region of the cooling portion treatment area than at a peripheral region of the cooling portion treatment area.33. The skin treatment device of claim 32 , wherein the cooling portion comprises a plurality of protrusions.34. The skin treatment device of claim 32 , wherein the density of the plurality of protrusions decreases from the central region of the cooling portion toward the peripheral region of the cooling portion.35. The skin treatment device of claim 32 , wherein a distal end size of the plurality of protrusions decreases from the central region of the cooling portion toward the peripheral region of the cooling portion.36. The skin treatment device of claim 32 , wherein the density of cooling contact area near the peripheral region of the cooling portion treatment area is configured to avoid excessive cooling of the skin tissue in areas of overlap between adjacent placements of the cooling portion against the skin ...

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Номер записи: 27
08-02-2018 дата публикации

METHOD AND APPARATUS FOR INFLATING AND DEFLATING BALLOON CATHETERS

Номер: US20180036057A1
Автор: ABBOUD Marwan, DESROCHERS Giles, HARMOUCHE Chadi, MAHROUCHE Rachid, MIHALIK Teresa Ann
Принадлежит:

A system and method for controlling the inflation, ablation, and deflation of a balloon catheter. The system includes a balloon catheter, a console, a pressurized gas or liquid inflation source, and an umbilical system to deliver pressurized coolant to the balloon catheter. The system may include controller that monitors the amount of pressure and volume within the balloon catheter. During inflation, the pressure and/or volume of fluid within the balloon is maintained at a target amount in order to provide sufficient mechanized pressure against the desired target region. The system limits the inflation pressure such that a safe quantity of gas would be released should a leak occur. If the amount falls below a certain threshold level, gas or fluid egress is presumed and the inflation process is halted. 1. A method of ablating tissue , the method comprising:delivering inflation fluid to an expandable treatment element of a medical device at a first target flow rate;positioning the medical device proximate an ablation site;delivering inflation fluid to the expandable treatment element at a second target flow rate that is greater than the first target flow rate; andablating the tissue with the expandable treatment element.2. The method of claim 1 , wherein the inflation fluid is transferred to the expandable treatment element under a fixed flow pressure.3. The method of claim 1 , wherein the medical device includes at least one of a temperature sensor claim 1 , a pressure sensor claim 1 , and a flow rate sensor.4. The method of claim 3 , further comprising:detecting a flow rate of the inflation fluid to the expandable treatment element; andadjusting the flow rate of the inflation fluid to the expandable treatment element based on the detected flow rate.5. The method of claim 4 , wherein the flow rate of the inflation fluid to the expandable treatment element is adjusted automatically by at least one valve claim 4 , the at least one valve being in communication with a ...

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Номер записи: 28
07-02-2019 дата публикации

CRYOSURGICAL INSTRUMENT

Номер: US20190038333A1
Автор: Adler Marcus, Andel Hanna, Brodbeck Achim, Fischer Klaus, Kronenthaler Joerg
Принадлежит:

A cryosurgical instrument includes a feed line for conveying fluid into an expansion chamber. The feed line has a capillary line section that terminates in the expansion chamber and forms an aperture for the fluid to undergo the Joule-Thomson effect. The flow cross-section of the feed line decreases in at least one transition section of the feed line in the form of a funnel. Following each transition section there preferably follows a step section, in which latter section the flow cross-section is preferably largely constant. The last step section is preferably formed by the capillary line section. Due to the acceleration of the fluid in the transition sections and the abating of pressure fluctuations in the capillary tube section and, optionally in the additional step sections, the expansion range in the expansion chamber is increased, without impeding the backflow of the expanded gas out of the expansion chamber. 110. A cryosurgical instrument () , comprising:{'b': 15', '18', '15', '21', '18, 'a feed line () for supplying a fluid into an expansion chamber (), wherein the feed line () has a capillary line section () that terminates in the expansion chamber (),'}{'b': 19', '18', '18, 'a return system () connected to the expansion chamber () for returning gas out of the expansion chamber (),'}{'b': 15', '30', '2', '30', '1', '30', '1', '30', '33, 'i': n', 'n', 'n', 'n, 'wherein the feed line () has at least one first section (-, -) and one second section (-, ) with different-size interior cross-sections (),'}{'b': 15', '32', '2', '32', '1', '30', '2', '30', '1', '30', '1', '30', '34', '18, 'i': n', 'n', 'n', 'n', 'n', 'n, 'wherein a flow path through the feed line () tapers in a form of a funnel in a transition section (-, -) from the first section (-, -) to the second section (-, ) in a direction of flow () of the fluid toward the expansion chamber ().'}210153212130nn. The cryosurgical instrument () according to claim 1 , wherein the flow path in the feed line () ...

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Номер записи: 29
07-02-2019 дата публикации

Instrument For Therapeutically Cytotoxically Ablating Parathyroidal Tissue Within A Parathyroid Gland

Номер: US20190038334A1
Автор: Schwartz Alan N.
Принадлежит:

An instrument for therapeutically cytotoxically ablating parathyroidal tissue is disclosed. A substance is capable of transforming the parathyroid gland from overproduction of parathyroid hormone when the substance's quantity exceeds a set amount, and is capable of transforming the parathyroid gland from overproduction only when activated by application of sufficient units of an electromagnetic energy having a frequency ranging from 400 THz to 30 PHz when the substance's quantity is below the set amount. A delivery device is operable to introduce the substance into the parathyroidal tissue and to quantitatively limit the quantity to below the set amount. An energy device is operable to apply units of the electromagnetic energy after the substance has been introduced. A sensor is operable to monitor the activation of the substance as the electromagnetic energy is applied. The energy device is further operable to modulate applying the electromagnetic energy when the substance has been activated. 1. An instrument for therapeutically cytotoxically ablating parathyroidal tissue within a parathyroid gland , comprising:a substance capable of cytotoxic ablation of a parathyroid gland of a living human, wherein the substance alone is capable of transforming the parathyroid gland from overproduction to non-overproduction of parathyroid hormone when a quantity of the substance exceeds a set amount, and the substance is capable of transforming the parathyroid gland from overproduction to non-overproduction of the parathyroid hormone only when activated in the parathyroidal tissue by application of sufficient units of an electromagnetic energy having a frequency ranging from 400 THz to 30 PHz when the quantity of the substance is below the set amount;a substance delivery device operable to introduce the substance into the parathyroidal tissue and to quantitatively limit the quantity of the substance being introduced to below the set amount;an electromagnetic energy treatment ...

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Номер записи: 30
18-02-2021 дата публикации

Flexible cryoprobe

Номер: US20210045794A1
Автор: Graig Kveen, Harishankar Natesan, Satish Ramadhyani
Принадлежит: BIOCOMPATIBLES UK LTD

A cryoablation tool may include a catheter. The catheter may have a shaft having: a proximal end, a distal end, a shaft wall extending between the proximal end and the distal end, the shaft wall having an outer surface and an inner surface and a vacuum gap defined therebetween that forms a vacuum chamber, the inner surface of the shaft wall being gas permeable, a shaft lumen bounded by the inner surface of the shaft wall, the shaft lumen for carrying a cryogen gas, and the vacuum chamber having a proximal opening connectable to a vacuum source, the proximal opening establishing vacuum communication between the vacuum chamber and the vacuum source.

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Номер записи: 31
12-02-2015 дата публикации

Cyrogenic treatment systems

Номер: US20150045780A1
Автор: Benjamin D. Voiles, Brian M. Neil, Daniel R. BURNETT, David Beaulieu, Ric Cote, William W. Malecki
Принадлежит: Channel Medsystems Inc

Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure and temperature sensing elements which may allow for control of the pressure and temperature within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled, room temperature, or warmed fluid such as water may then be used to rapidly terminate the treatment session.

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Номер записи: 32
15-02-2018 дата публикации

CRYOSURGERY SYSTEM

Номер: US20180042655A1
Автор: Burr Ron, Cordero Rafael, Davidson Marc, Maners Wendelin Cherise, Petrilli Janel
Принадлежит:

A cryosurgery system for application of medical-grade liquid nitrogen to a treatment area via a small, low pressure, open tipped catheter. The system includes a console, including a touch panel computer, a cryogen module, a suction module and an electronics module, and a disposable spray kit. Features include optional low cryogen flow setting to reduce the cryogen flow rate by 50%, improved cryogen flow consistency reducing pressure pulses and peaks, an integrated suction pump for improved consistency and self-checks, specified vent tube areas and corresponding maximum expected pressures during cryospray procedure; optional pressure sensing capability to monitor pressure during a treatment, and novel catheter designs of multilayer and flexible construction providing a variety of spray patterns. 1. An apparatus for cryogen spray treatment , comprising:a tank and a pressure maintenance system, wherein cryogen is stored in the tank under pressure and the maintenance system controls pressure of the cryogen while in the tank and during delivery to a patient;a delivery catheter communicating with the tank for delivery of cryogen spray to the patient during the treatment;a defrost system configured to defrost the catheter prior to or after the cryogen spray treatment, or both; andan on-board control system and user interface, comprising a non-transitory computer readable medium containing executable computer readable instructions for one or both of user-programmed and user-direct monitoring and control of the pressure maintenance system, the catheter, and the defrost system.2. The apparatus according to claim 1 , further comprising an endoscope claim 1 , wherein the delivery catheter is configured to be inserted within the patient through the endoscope and deliver the cryogen spray to a target area during the treatment.3. The apparatus according to claim 1 , wherein the delivery catheter comprises an inner extruded polymeric tube claim 1 , a layer of braided wire over the ...

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Номер записи: 33
23-02-2017 дата публикации

Endovascular near critical fluid based cryoablation catheter having plurality of preformed treatment shapes

Номер: US20170049495A1
Автор: Alexei Babkin, Steven Kovalcheck, Xiaoyu Yu
Принадлежит: Adagio Medical Inc

An endovascular near critical fluid based cryoablation catheter for creating an elongate lengthwise-continuous lesion in tissue comprises an elongate shaft, a flexible distal tissue treatment section, and a distal tip. A plurality of flexible tubes extend through the distal treatment section to transport a near critical fluid to and from the distal tip. The distal treatment section is controllably deployed to match the contour of an anatomical region to be treated. In embodiments the distal treatment section includes a superelastic material and can assume a plurality of different shapes based on the distance ejected from an outer sleeve member. When the catheter is activated, heat is transferred between a target tissue and the distal treatment section of the catheter thereby creating the elongate lengthwise-continuous lesion in the tissue.

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Номер записи: 34
20-02-2020 дата публикации

INTEGRITY TESTING OF STORAGE TANK STRUCTURE USING ROBOTIC ULTRASOUND

Номер: US20200054379A1
Автор: Rubin Sheldon, Walker Stephen Edward
Принадлежит: SONASEARCH, INC.

Systems and methods are provided for non-destructive inspection of an interior of a vessel filled with a liquid. 1. A system configured to non-destructively inspect the integrity of an interior of a vessel , the system comprising:a vessel surveyor comprising at least one ultrasound transducer and a plurality of thrusters configured to assist the vessel surveyor to swim through a liquid contained within the vessel;an acoustic tracking system configured to track the location of the vessel surveyor in the vessel; anda telemetry system configured to receive and compile data from the at least one ultrasound transducer and the acoustic tracking system, wherein the telemetry system is pre-loaded with a template of the interior of the vessel, including positions of floor plates or any obstacles.2. The system of claim 1 , wherein the at least one ultrasound transducer is configured to measure both a floor and a wall of the vessel from a single position of the vessel surveyor.3. The system of claim 1 , further comprising a plurality of ultrasound transducers.4. The system of claim 1 , wherein the acoustic tracking system comprises at least one pinger and at least three hydrophone base stations.5. The system of claim 4 , wherein the at least three hydrophone base stations are disposed on an outside of the vessel.6. The system of claim 1 , further comprising a safety interlock comprising a pressure transmitter configured to continuously measure ambient pressure at the top of the vessel surveyor.7. The system of claim 6 , wherein the safety interlock is configured to prevent the vessel surveyor claim 6 , when descending into the vessel claim 6 , from being powered until it is below a pre-determined exclusion zone.8. The system of claim 6 , wherein the safety interlock is configured to prevent the vessel surveyor claim 6 , when ascending from the bottom of the vessel claim 6 , from being powered when it reaches a pre-determined exclusion zone.9. The system of claim 6 , wherein ...

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Номер записи: 35
28-02-2019 дата публикации

Cryogenic ablation system with rotatable and translatable catheter

Номер: US20190059970A1
Автор: Cesar A. Ico, Dennis Franklin BURKE, Gabriel F.W. NEWELL, Patrick P. Wu, Timothy Douglas Holland
Принадлежит: Pentax of America Inc

An ablation assembly includes a handle, a catheter assembly and a connector locking assembly. The catheter assembly includes: a catheter shaft, a balloon and a connector at the distal and proximal ends of the catheter shaft, and a delivery tube extending between there between. The connector includes a connector body secured to the proximal end and a plug secured to the delivery tube, the plug and delivery tube movable axially and rotationally. The handle includes an open portion receiving the plug and the connector body. The connector locking assembly includes: means for simultaneously automatically connecting the plug and the connector body to the handle to place the connector in a load state prior to use, and means for automatically releasing the connector body and thereafter the plug from the handle to place the connector in an eject state to permit the connector to be removed from the handle.

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Номер записи: 36
17-03-2022 дата публикации

Devices and methods for fluid distribution from a catheter

Номер: US20220079649A1
Автор: Thomas I. Mulcahey
Принадлежит: United States Endoscopy Group Inc

The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to devices and methods to convey fluid delivered from a delivery catheter. Exemplary catheters are disclosed which include fluid distribution devices for delivery of fluid and delivery of pass-through medical instruments, such as cryodecompression tubes, within body lumens.

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Номер записи: 37
10-03-2016 дата публикации

Methods, systems and devices for cryogenic biopsy

Номер: US20160066896A1
Автор: Allison Mary Day, Amy Levasseur, Briana Moretti, Donald C. von Linden, JR., John Allen HINGSTON, Paul Smith, Sujit Tatke, William ABNER
Принадлежит: Boston Scientific Scimed Inc

Cryogenic biopsy assemblies are described herein that comprise a tissue acquisition device and cryogenic probe. Also disclosed are systems containing such cryogenic biopsy assemblies and methods cryogenic biopsy that employ such cryogenic biopsy assemblies.

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Номер записи: 38
27-02-2020 дата публикации

System and method for inflating a cryoablation balloon catheter

Номер: US20200060746A1
Автор: Chadi Harmouche
Принадлежит: Boston Scientific Scimed Inc, Cryterion Medical Inc

A system for inflating a cryogenic ablation catheter balloon, the system comprising a fluid source containing a fluid in a liquid state, a first supply line fluidly coupled to the fluid source and configured to be fluidly coupled to an internal space within the cryogenic ablation catheter balloon, the first supply line including an inline multi-stage pressure regulating system. The multi-stage pressure regulating system includes a first stage configured to cause the fluid to transition from the liquid state to a gas state, and a second stage downstream of the first stage configured to maintain the fluid downstream of the second stage at a pressure corresponding to an inflation pressure of cryogenic ablation catheter balloon.

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Номер записи: 39
08-03-2018 дата публикации

MRI-COMPATIBLE CRYOCATHETERS AND SYSTEM

Номер: US20180064481A1
Автор: COULOMBE Nicolas, DEAC Ioana, Horrigan John B., LALONDE Jean-Pierre, WITTENBERGER Dan
Принадлежит:

A system and device for cryoablation of tissue that is suitable for use within an MRI environment. The device may include an elongate body, a treatment element at the distal portion of the elongate body, and one or more pull fibers. The pull fibers may be composed of a non-ferromagnetic material, such as a polymer. Likewise, none of the other device components may be composed of a ferromagnetic material. The device may also include at least one fiber optic sensor. The elongate body distal portion may include a distal tip to which the pull fibers are directly coupled. Additionally or alternatively, the elongate body may include one or more pull fiber lumens configured to allow the pull fibers to deflect the distal portion when a pull force is exerted on the pull fibers. 1. An MRI-compatible medical device , the medical device comprising:an elongate body including a proximal portion and a distal portion;a treatment element at the distal end of the elongate body; anda non-ferromagnetic pull fiber coupled to the elongate body distal portion.2. The MRI-compatible medical device of claim 1 , wherein the elongate body further includes a first pull fiber lumen claim 1 , a second pull fiber lumen claim 1 , and a main lumen.3. The MRI-compatible medical device of claim 2 , wherein the elongate body further includes a longitudinal axis claim 2 , the main lumen being coaxial with the longitudinal axis and the first and second pull fiber lumens being diametrically opposite each other and at least substantially parallel to the central lumen.4. The MRI-compatible medical device of claim 3 , wherein the elongate body further includes a connecting lumen that is in communication with each of the first and second pull fiber lumens claim 3 , the connecting lumen lying in a plane that is substantially orthogonal to the longitudinal axis.5. The MRI-compatible medical device of claim 4 , wherein the connecting lumen is curved around the main lumen.6. The MRI-compatible medical device of ...

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Номер записи: 40
08-03-2018 дата публикации

VARIABLE GEOMETRY COOLING CHAMBER

Номер: US20180064482A1
Автор: ABBOUD Marwan, DEAC Ioana, WITTENBERGER Dan
Принадлежит:

The present invention provides a medical device that may include a catheter body having proximal and distal portions, a fluid injection lumen disposed within elongate body, and a guidewire lumen disposed within the elongate body. A tip portion defining a cavity in fluid communication with the fluid injection lumen may be coupled to the distal end of the guidewire lumen, and an expandable element may be coupled to the distal portion of the catheter body and to the tip portion, such that the expandable element is in fluid communication with the fluid injection lumen. A shaping element may at least partially surround the expandable element, where the shaping element is configurable in a first geometric configuration and a second geometric configuration. 1. A medical device , comprisingan elongate body including a proximal portion, a distal portion, and a fluid injection lumen;an expandable element coupled to the elongate body, the expandable element being in fluid communication with the fluid injection lumen; anda mesh at least partially surrounding the expandable element, the mesh being transitionable between a first geometric configuration having an elongated, substantially cylindrical shape and a second geometric configuration having a substantially cylindrical shape.2. The medical device of claim 1 , further comprising an actuator element claim 1 , the actuator element being able to cause the mesh to transition from the first geometric configuration to the second geometric configuration.3. The medical device of claim 2 , wherein the elongate body further includes a guidewire lumen having a distal tip claim 2 , the distal tip defining a cavity in fluid communication with the fluid injection lumen.4. The medical device of claim 3 , wherein the expandable element includes an interior chamber claim 3 , the cavity within the distal tip being fluidly isolated from the interior chamber.5. The medical device of claim 3 , wherein the actuator element is in mechanical ...

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Номер записи: 41
08-03-2018 дата публикации

CATHETERS WITH ENHANCED FLEXIBILITY AND ASSOCIATED DEVICES, SYSTEMS, AND METHODS

Номер: US20180064907A1
Автор: Beasley Rudy, Goshgarian Justin, Ku Vincent
Принадлежит:

A neuromodulation catheter includes an elongate shaft and a neuromodulation element. The shaft includes two or more first cut shapes and two or more second cut shapes along a helical path extending around a longitudinal axis of the shaft. The first cut shapes are configured to at least partially resist deformation in response to longitudinal compression and tension on the shaft and torsion on the shaft in a first circumferential direction. The second cut shapes are configured to at least partially resist deformation in response to longitudinal compression on the shaft and torsion on the shaft in both first and second opposite circumferential directions. 1. A neuromodulation catheter , comprising: two or more first cut shapes, the first cut shapes being configured to at least partially resist deformation in response to compression on the shaft along a longitudinal axis of the shaft, tension on the shaft along the longitudinal axis, and torsion on the shaft in a first circumferential direction perpendicular to the longitudinal axis, and', 'two or more second cut shapes, the second cut shapes being configured to at least partially resist deformation in response to compression on the shaft along longitudinal axis, torsion on the shaft in the first circumferential direction, and torsion on the shaft in a second circumferential direction opposite to the first circumferential direction; and, 'an elongate shaft including—'}a neuromodulation element operably connected to the shaft via a distal end portion of the shaft, the first and second cut shapes are interspersed along a helical path extending about the longitudinal axis,', 'the first cut shapes are less resistant to deformation in response to torsion on the shaft in the second circumferential direction than are the second cut shapes, and', 'the second cut shapes are less resistant to deformation in response to tension on the shaft along the longitudinal axis than are the first cut shapes., 'wherein—'}2. The ...

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Номер записи: 42
15-03-2018 дата публикации

SHAPE CHANGING ABLATION BALLOON

Номер: US20180071005A1
Автор: DAVIE Scott W., LALONDE Jean-Pierre
Принадлежит:

A device, method, and system for thermally affecting tissue. The device may generally include an elongate body, an actuation element slidably disposed within the elongate body, a balloon defining an interior chamber, a proximal neck, and a distal neck, the first neck being coupled to the distal portion of the elongate body and the second neck being coupled to the distal portion of the actuation element, retraction of the actuation element within the elongate body causing the treatment element to transition from a first configuration to a second configuration. The distal neck may be located external to the interior chamber in the first configuration and within the interior chamber in the second configuration. The device may also include a fluid injection element that is transitionable to an expanded configuration when the balloon is inflated, thereby enhancing the cooling capacity of the balloon. 1. A method for performing a pulmonary vein isolation procedure , the method comprising: an elongate body including a distal portion and a proximal portion;', 'an actuation element slidably disposed within the elongate body, the actuation element including a distal portion and a proximal portion;', 'an inflatable treatment element defining an interior chamber, a first neck, and a second neck, the first neck being coupled to the distal portion of the elongate body and the second neck being coupled to the distal portion of the actuation element, the inflatable treatment element being transitionable between a first configuration and a second configuration, each of the first and second necks being located external to the interior chamber when the inflatable treatment element is in the first configuration; and', 'a fluid injection element located within the interior chamber, at least a portion of the fluid injection element being coiled around and substantially in contact with a portion of the actuation element;, 'positioning a medical device proximate a pulmonary vein ostium, ...

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Номер записи: 43
15-03-2018 дата публикации

APPARATUS AND METHODS FOR REGULATING CRYOGENIC TREATMENT

Номер: US20180071006A1
Автор: BEAULIEU David, BURNETT Daniel R., COTE Ric, Lopresti Vincent, MALECKI William W., NEIL Brian M., VOILES Benjamin D.
Принадлежит: Channel Medsystems, Inc.

Apparatus and methods for regulating cryogenic treatments are disclosed which comprise devices and methods for delivering controlled treatment of a cryoablative agent. In one variation, such devices may generally comprise an elongate probe having a distal tip and a flexible length, at least one infusion lumen positioned through or along the elongate probe, wherein the infusion lumen defines one or more openings along its length, and a liner expandably enclosing the probe. An inflow reservoir or canister valve may be fluidly coupled with a reservoir or canister containing the cryoablative agent and a modulation control unit may also be fluidly coupled with the inflow reservoir or canister valve and in fluid communication with the at least one infusion lumen. Additionally, a warming element may also be thermally coupled with the reservoir or canister. 1. A tissue treatment system , comprising:a handle having a housing;an elongate probe extending from the housing and having a distal tip and a flexible length;a liner expandably enclosing the probe;at least one infusion lumen positioned through or along the elongate probe, wherein the infusion lumen defines one or more openings along its length;at least one delivery lumen slidingly positioned through or along the infusion lumen, wherein proximal translation of the delivery lumen relative to the infusion lumen increases a number of unobstructed openings along the infusion lumen; anda tether extending through an interior of the liner and connected to a distal portion of the liner, wherein tensioning of the tether retracts the distal portion of the liner proximally.2. The system of further comprising one or more pressure sensors in communication with the interior of the liner.3. The system of further comprising a controller in communication with the one or more pressure sensors claim 2 , wherein the controller is programmed to monitor pressure while a cryoablative fluid or gas is infused into the interior via the infusion ...

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Номер записи: 44
05-03-2020 дата публикации

Ablation catheters

Номер: US20200069364A1
Автор: Amr Salahieh, Brian D. Brandt, Emma LEPAK, John P. Claude, Jonah Lepak, Tom Saul
Принадлежит: Individual

Cardiac tissue ablation catheters including an inflatable and flexible toroidal or spherically shaped balloon disposed at a distal region of an elongate member, a flexible circuit carried by an outer surface of the balloon, the flexible circuit including, a plurality of flexible branches conforming to the radially outer surface of the balloon, each of the plurality of flexible branches including a substrate, a conductive trace carried by the substrate, and an ablation electrode carried by the substrate, the ablation electrode in electrical communication with the conductive trace, and an elongate shaft comprising a guidewire lumen extending in the elongate member and extending from a proximal region of the inflatable balloon to distal region of the inflatable balloon and being disposed within the inflatable balloon, wherein a distal region of the elongate shaft is secured directly or indirectly to the distal region of the inflatable balloon.

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Номер записи: 45
14-03-2019 дата публикации

Ablation catheter having a shape memory stylet

Номер: US20190076179A1
Автор: Alexei Babkin, David Cabrita, Faysal S. Ahmed, Meital Mazor, Pedram Nourian
Принадлежит: Adagio Medical Inc

An ablation apparatus for creating a lesion in target tissue, the ablation apparatus having an ablation shaft including a handle, a first portion, an ablation portion, distal tip, at least one ablation energy delivery lumen, at least one ablation energy return lumen, and a stylet lumen that extends substantially along a length of the ablation shaft from the handle to at least the ablation portion. The ablation apparatus also includes a stylet that is capable of being inserted into the stylet lumen where the stylet is made of a shape-memory material.

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Номер записи: 46
24-03-2016 дата публикации

Systems and methods for cryoablation of a tissue

Номер: US20160081735A1
Автор: Ghassan S. Kassab, Jose A. Navia, SR.
Принадлежит: CVDevices LLC

Systems and methods for cryoablation of a tissue. In at least one embodiment of a cryoablation system of the present disclosure, the cryoablation system comprises an expandable stent comprising a proximal end and a distal end, a sidewall defining a lumen extending between the proximal end and the distal end, and a cryoablation chamber at the distal end, the expandable stent configured to permit blood flow therethrough, and a cryoablation device comprising at least one coolant tube at least partially positioned within the cryoablation chamber, wherein the at least one coolant tube is operable to produce a cryogenic environment sufficient to ablate at least a portion of a tissue engaged within the cryoablation chamber.

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Номер записи: 47
31-03-2022 дата публикации

Catheter apparatuses for modulation of nerves in communication with the pulmonary system and associated systems and methods

Номер: US20220096153A1
Автор: Martin Rothman, Paul Coates
Принадлежит: Medtronic Ardian Luxembourg SARL

Devices, systems, and methods for the selective positioning of an intravascular neuromodulation device are disclosed herein. Such systems can include, for example, an elongated shaft and a therapeutic assembly carried by a distal portion of the elongated shaft. The therapeutic assembly is configured for delivery within a blood vessel. The therapeutic assembly can include a pre-formed shape and can be transformable between a substantially straight delivery configuration; and a treatment configuration having the pre-formed helical shape to position the therapeutic assembly in stable contact with a wall of the body vessel. The therapeutic assembly can also include a mechanical decoupler operably connected to the therapeutic assembly that is configured to absorb at least a portion of a force exerted on the therapeutic assembly by the shaft so that the therapeutic assembly maintains a generally stationary position relative to the target site.

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Номер записи: 48
26-03-2015 дата публикации

Cryotherapeutic devices for renal neuromodulation and associated systems and methods

Номер: US20150088113A1
Автор: Benjamin J. Clark, Brian Kelly, David J. Hobbins, Grace Kelly, Tim Huynh
Принадлежит: Medtronic Ardian Luxembourg SARL

Cryotherapeutic devices for renal neuromodulation and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having a distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator having a distributor in fluid communication with the supply lumen and a balloon configured to deliver cryotherapeutic cooling to nerves proximate the treatment site when the cooling assembly is in a deployed state.

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Номер записи: 49
21-03-2019 дата публикации

APPARATUS AND METHODS FOR TREATING RHINITIS

Номер: US20190083157A1
Автор: SAADAT Vahid
Принадлежит:

Apparatus and methods for treating conditions such as rhinitis are disclosed herein where a distal end of a probe shaft is introduced through the nasal cavity where the distal end has an end effector with a first configuration having a low-profile which is shaped to manipulate tissue within the nasal cavity. The distal end may be positioned into proximity of a tissue region having a post nasal nerve associated with a middle or inferior nasal turbinate. Once suitably positioned, the distal end may be reconfigured from the first configuration to a second configuration which is shaped to contact and follow the tissue region and the post nasal nerve may then be ablated via the distal end. Ablation may be performed using various mechanisms, such as cryotherapy, and optionally under direct visualization. 1. A system for applying RF energy in a nasal region of a human patient , the system comprising:a shaft having a proximal portion and a distal portion, wherein the shaft is configured to locate the distal portion at a target site in a nasal cavity, wherein the target site is at least one of proximate to a sphenopalatine foramen of a human patient, or inferior to the sphenopalatine foramen;a therapeutic assembly at the distal portion of the shaft and transformable between a low-profile delivery state and an expanded state, wherein the therapeutic assembly comprises:a plurality of struts arranged in at least two branches radially spaced apart from each other when the therapeutic assembly is in the expanded state;a plurality of electrodes disposed on the struts;wherein the therapeutic assembly is configured to conform to anatomical structures adjacent to the target site and to place at least two of the electrodes in contact with tissue at the target site when the therapeutic assembly is in the expanded state, andwherein the electrodes are configured to apply radiofrequency (RF) energy to the target site to therapeutically treat at least one nasal nerve.2. The system of claim ...

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Номер записи: 50
02-04-2015 дата публикации

Cylindrical probe outer casing for cryosurgery device, and treatment unit

Номер: US20150094700A1
Автор: Kansei Iwata
Принадлежит: DGS COMPUTER Co Ltd

There are provided an external cylinder for a probe equipped in a cryosurgical apparatus and a therapeutic-device unit, which are able to protect normal cells near a lesion, provide higher heat efficiency for the freeze and thawing, and simplify the structure. The external cylinder for the probe equipped in the cryosurgical apparatus and the therapeutic-device unit which includes the external cylinder for the probe equipped in the cryosurgical apparatus are provided. The external cylinder includes a given range in which the freezing gas enables an ice ball to be formed on an outer circumference including the distal end portion; and adiabatic means arranged in a range other than the given range so as to prevent heat from being exchanged between the inner space and an outside.

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Номер записи: 51
19-03-2020 дата публикации

Pulmonary vein isolation balloon catheter

Номер: US20200085484A1
Автор: Derek Sutermeister, Salome A. Gonzalez, Troy T. Tegg
Принадлежит: St Jude Medical Cardiology Division Inc

The instant disclosure relates to electrophysiology catheters for tissue ablation. In particular, the instant disclosure relates to a cryogenic ablation balloon with safety features that facilitate identification of a leak into an interstitial space between inner and outer balloons as part of the ablation balloon catheter assembly, and prevents egress of cryogenic fluid out of the ablation balloon.

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Номер записи: 52
19-03-2020 дата публикации

CRYOPROBE

Номер: US20200085485A1
Автор: FAGO Frank, Frangolis Todd, SKORICH Stefan, Widenhouse Christopher, Wilson David
Принадлежит: AtriCure, Inc.

Cryosurgical devices, such as cryosurgical probes (cryoprobes) are disclosed. Some example embodiments may include an elongated shaft at least partially housing or delineating a fluid supply conduit and a fluid exhaust conduit, the elongated shaft including a distal ablation section terminating at a closed distal end, a housing at least partially circumscribing at least a portion of a proximal end of the elongated shaft and receiving or delineating at least a portion of the fluid supply conduit and a portion of the fluid exhaust conduit; and/or a flow restricting element in fluid communication with the fluid exhaust conduit, the flow restricting element regulating the flow of fluid through at least a portion of the fluid exhaust conduit. 1. A cryogenic probe comprising:an elongated shaft at least partially housing or delineating a fluid supply conduit and a fluid exhaust conduit, the elongated shaft including a distal ablation section terminating at a closed distal end;a housing at least partially circumscribing at least a portion of a proximal end of the elongated shaft and receiving or delineating at least a portion of the fluid supply conduit and a portion of the fluid exhaust conduit; anda flow restricting element in fluid communication with the fluid exhaust conduit, the flow restricting element regulating the flow of fluid through at least a portion of the fluid exhaust conduit.2. The cryogenic probe of claim 1 , wherein the flow restricting element comprises a constriction fluidicly interposing the fluid exhaust conduit and an exhaust line.3. The cryogenic probe of claim 2 , wherein a cross-sectional area for fluid flow of the constriction is less than about 70% of a cross-sectional area for fluid flow of the exhaust line.4. The cryogenic probe of claim 2 , wherein a cross-sectional area for fluid flow of the constriction is less than about 50% of a cross-sectional area for fluid flow of the exhaust line.5. The cryogenic probe of claim 2 , wherein a cross- ...

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Номер записи: 53
07-04-2016 дата публикации

ABLATION TECHNIQUES FOR THE TREATMENT OF ATRIAL FIBRILLATION

Номер: US20160095656A1
Автор: Mirabito A. Jason, Peled Omer
Принадлежит:

A catheter device provides a balloon structure and a side-firing laser lumen within the balloon to create lesions in the pulmonary vein (PV) in the treatment of atrial fibrillation. Mounted on the balloon so as to contact the PV when the balloon is inflated are one or more electrodes which may be used in a measurement mode, a treatment mode, or both. 1. A device for insertion in the pulmonary vein for the treatment of atrial fibrillation , the device comprising;a plurality of substantially parallel apertured lumens having distal and proximal ends;an inflatable balloon in the vicinity of the distal ends of the lumens, the apertured lumens having openings in the distal ends of the lumens within the inflatable balloon;at least one electrode formed on the balloon, wherein the at least one electrode is suitable for one or both of measurement and treatment of the pulmonary vein;the plurality of lumens being suitable for the introduction and the evacuation of a cryogenic fluid into the balloon;a controller operatively connected to control the operation of the at least one electrode and to control a source of cryogenic fluid wherein, when the inflatable balloon is caused to be inflated with cryogenic fluid by the controller to treat the pulmonary vein, the at least one electrode comes into contact with the pulmonary vein wall, the controller then causing the at least one electrode to one of or both of measure or treat the pulmonary vein.2. The device of claim 1 , wherein the controller is further operable to operate the at least one electrode to measure treatment parameters after treatment by one or both of cryogenic fluids and the at least one electrode.3. The device of claim 1 , wherein the at least one electrode is one or a RF or an ultrasonic electrode.4. The device of claim 1 , further comprising a plurality of electrodes claim 1 , the plurality of electrodes being one or more of RF electrodes claim 1 , ultrasonic electrodes or a mixture of RF and ultrasonic electrodes ...

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Номер записи: 54
12-05-2022 дата публикации

Systems and methods for variable injection flow

Номер: US20220142694A1
Автор: Claudia Lueckge, Dan Wittenberger, Jean-Pierre Lalonde, Mahmoud KABIR-SERAJ, Ramin Sabbaghe-Kermani, Regina E. GROVES, Timothy G. Laske
Принадлежит: MEDTRONIC CRYOCATH LP

A medical device having a catheter and a fluid delivery conduit entirely disclosed within a portion of the catheter. The catheter may have a thermally transmissive region in fluid communication with the fluid delivery conduit and a rod disposed within at least a portion of the fluid delivery conduit. The medical device may control variable fluid flow with the ability to modify the effective cross-sectional area of the fluid delivery conduit available for fluid flow. Additional configurations provided herein may allow for the selective manipulation of a footprint or therapeutic pattern achievable with the medical device during a single procedure, negating the need for the removal and insertion of multiple devices to achieve the same variations in treatment geometry or characteristics.

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Номер записи: 55
06-04-2017 дата публикации

Methods and devices to treat nasal airways

Номер: US20170095288A1
Автор: Andrew Frazier, Scott J. Wolf
Принадлежит: Aerin Medical Inc

Methods and devices for treating nasal airways are provided. Such devices and methods may improve airflow through an internal and/or external nasal valve, and comprise the use of mechanical re-shaping, energy application and other treatments to modify the shape, structure, and/or air flow characteristics of an internal nasal valve, an external nasal valve or other nasal airways.

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Номер записи: 56
12-04-2018 дата публикации

SYSTEMS AND METHODS OF PERFORMING MEDICAL PROCEDURES

Номер: US20180098810A1
Автор: FLAHERTY J. Christopher, Sherman Marshall, STEWART Mark T., WERNETH Randell L.
Принадлежит:

A medical method is provided, including a medical device having a distal assembly including at least one electrode and at least one treatment element, the medical device generating information regarding at least one of a physiological measurement and an operational parameter of the medical device; a plurality of surface electrodes affixable to a skin of the patient, wherein the surface electrodes are in electrical communication with the distal assembly to obtain position information of the medical device; and a processor pairing the position information and the at least one of a physiological measurement and an operational parameter of the medical device. 1. A medical method comprising:inserting a medical device into a body of a patient;obtaining position information of the medical device;treating a tissue site with the medical device;obtaining at least one of a physiological measurement of the tissue site and an operational parameter of the medical device;pairing the position information of the medical device with the at least one of a physiological measurement of the tissue site and an operational parameter of the medical device; andmodifying the treatment of the tissue site based at least in part on the paired information.2. The medical method of claim 1 , further comprising applying at least three pairs of surface electrodes to an area of skin of the patient.3. The medical method of claim 2 , wherein obtaining position information includes applying an electric potential between each of the three pairs of the surface electrodes and obtaining three-dimensional position information of the medical device.4. The medical method of claim 1 , further comprising graphically displaying the paired information.5. The medical method of claim 1 , wherein the medical device has a distal assembly with at least one electrode and at least one ablation element.6. The medical method of claim 5 , wherein the physiological measurement includes measuring an impedance proximate the ...

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Номер записи: 57
19-04-2018 дата публикации

VEIN OCCLUSION ASSESSMENT USING TEMPERATURE

Номер: US20180104006A1
Автор: MAHROUCHE Rachid, WITTENBERGER Dan
Принадлежит:

A medical system, comprising an ablation catheter is disclosed. The ablation catheter includes an elongate shaft with a proximal end, a distal end and a lumen disposed between the proximal end and the distal end. The ablation catheter also includes an expandable element in fluid communication with the lumen, a first temperature sensor operable to measure a first temperature; and a second temperature sensor operable to measure a second temperature. The first temperature sensor and the second temperature sensor are longitudinally separated from each other by at least a portion of the expandable element. 1. A method of assessing vein occlusion with an ablation catheter , the ablation catheter including: an elongate shaft with a proximal end , a distal end and a lumen disposed between the proximal end and the distal end; and an expandable element in fluid communication with the lumen; the method comprising:measuring a first temperature using a first temperature sensor; andmeasuring a second temperature using a second temperature sensor, the first temperature sensor and the second temperature sensor being longitudinally separated from each other by at least a portion of the expandable element.2. The method of claim 1 , further comprising:delivering a continuous flow of inflation fluid to the expandable element; anddetermining an extent of occlusion in the vein when the expandable element is inserted within the vein and inflated, the determining being based at least in part on a relationship of the first temperature and the second temperature.3. The method of claim 2 , further comprising:determining a temperature difference between the first temperature and the second temperature, the temperature difference indicating the extent of occlusion in the vein.4. The method of claim 2 , further comprising:analyzing a first temperature signal from the first temperature sensor;analyzing a second temperature signal from the second temperature sensor; andderiving a temperature ...

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Номер записи: 58
02-04-2020 дата публикации

Cardiac surgery cryoprobe

Номер: US20200100827A1
Автор: Cezary Górniak, Choudhary Sanjeev, Piotr Suwalski
Принадлежит: Medidata Sp Z OO

A cryoprobe having a working tip formed of two coaxial flexible internal and external tubular lines, wherein the cross-section diameter of the internal line is substantially smaller than the cross-section diameter of the external line, and the length is slightly smaller than the length of the external line. The external line ends with a top closing the working tip of the cryoprobe, while the end of the internal line is open, and there are openings evenly distributed across the circumference on at least half of the section of the internal line. On the section from the handle to the end located under the top, a resistance wire is spirally wound on the internal line, wherein the distance between the wall of the external line and the wall of the internal line is larger than the diameter of the resistance wire. On the external line, no further from the top located on the top of the working tip than ⅓ of the length thereof, there is a temperature sensor connected to the handle by a power line. External and internal lines corresponding to the external and internal lines come out from the working tip outside the handle, wherein the external and internal lines together with the harness of power lines and, insulated with an insulating hose, are connected from the handle to the unit supplying air and liquid nitrogen at low pressure of up to 0.5 bars using a pump system.

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Номер записи: 59
03-05-2018 дата публикации

METHODS AND DEVICES FOR CRYOGENIC CAROTID BODY ABLATION

Номер: US20180116704A1
Автор: Gelfand Mark, Ryba Eric
Принадлежит:

Methods and cryogenic devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via carotid body ablation. Some methods include advancing a cryo-ablation catheter into a patient's vasculature and ablating tissue within a carotid septum. 1. A method for cryo-ablating target tissue within a carotid septum of a patient , the method comprising:advancing a balloon catheter towards a bifurcation of an internal carotid artery and an external carotid artery of a patient, the balloon catheter comprising a first arm and an expandable balloon,passing the first arm into the internal carotid artery and engaging the first arm with the carotid artery bifurcation;passing the balloon into the external carotid artery and expanding the balloon;advancing a cryo-ablation catheter supporting a cryo-ablation element out of an exit port in the catheter such that the cryo-ablation element is disposed adjacent the carotid septum; andactuating the cryo-ablation element to ablate at least a portion of the carotid septum.2. The method of further comprising retracting a sheath to cause the first arm to assume a preformed configuration in which it extends from an axis of the balloon catheter at between about 30 and about 60 degrees.3. The method of wherein advancing a cryo-ablation catheter out of an exit port comprises advancing a cryo-ablation catheter out of a side exit port in the catheter.4. The method of further comprising engaging the cryo-ablation element with the wall of the external carotid artery.5. The method of wherein advancing a cryo-ablation catheter out of an exit port comprises advancing a cryo-ablation catheter out of an exit port in the catheter and into the interior of the expandable balloon.6. The method of further comprising engaging the cryo-ablation element into contact with interior of the balloon wall.7. A method for ...

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Номер записи: 60
16-04-2020 дата публикации

CRYO NEEDLE GUIDE

Номер: US20200113613A1
Автор: MARTINEZ BRADLEY, Medina Pablo, Venkataraman Rajesh, Xu Yang
Принадлежит:

A needle guidance assembly for constraining and guiding an interventional needle is provided. The needle guidance assembly includes a needle guide having opposing lever arms. Jaws of the opposing lever arms form a guide bore configured to receive an interventional needle and orient the needle with respect to, for example, an imaging probe. Constraining the needle within the imaging field of the probe allows for real-time monitoring during insertion of the interventional needle into patient tissue. In addition, the needle guidance assembly is angularly positionable relative to the image field to allow advancement of the needle to a target site within the imaging field. 1. A needle guide for medical diagnoses and treatment , comprising:first and second lever arms;a pivot pin connecting the first and second lever arms and defining a pivot point between the first and second lever arms, wherein each of the first and second lever arms include a jaw and a handle extending from the jaw on an opposing side of the pivot point, wherein the first and second lever arms have a closed configuration in which the jaws are in physical contact and the handles are spaced apart by a maximum distance and an open configuration in which the jaws are spaced apart and the handles are spaced apart by less than the maximum distance; anda guide bore configured to receive an interventional needle, wherein the guide bore is defined by the jaws when in the closed configuration.2. The needle guide of claim 1 , wherein the first lever arm includes a first recessed channel along the length of the jaw of the first lever arm and the second lever arm includes a second recessed channel along the length of the jaw of the second lever arm claim 1 , wherein the first and second recessed channels form the guide bore when in the closed configuration.3. The needle guide of claim 2 , wherein the first and second recessed channels are contiguous in the closed configuration and completely enclose the guide bore.4 ...

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Номер записи: 61
16-04-2020 дата публикации

ABLATION TECHNIQUES FOR THE TREATMENT OF ATRIAL FIBRILLATION

Номер: US20200113626A1
Автор: Mirabito Anthony Jason, Peled Omer
Принадлежит:

A catheter device provides a balloon structure and a side-firing laser lumen within the balloon to create lesions in the pulmonary vein (PV) in the treatment of atrial fibrillation. Mounted on the balloon so as to contact the PV when the balloon is inflated are one or more electrodes which may be used in a measurement mode, a treatment mode, or both. 18-. (canceled)9. A method of treating a human for atrial fibrillation , the method comprising:providing a device suitable for insertion into the pulmonary vein for the treatment of atrial fibrillation, the device comprising: at least one apertured lumen having distal and proximal ends; an inflatable balloon in the vicinity of the distal end of the lumen; an optical fiber at least partially within the at least one lumen and disposed along the axis of the lumen, the optical fiber being suitable for conveying a beam of laser energy; at least one opening in the vicinity of the distal end and within the inflatable balloon; an optical device on the optical fiber in the vicinity of the distal end and within the balloon to deflect a laser beam introduced in the vicinity of the proximal end and exiting in the vicinity of the distal end of the lumen at angles other than along the lumen axis, wherein the deflected laser energy impinges on the pulmonary vein wall through the inflated balloon; the optical fiber being rotatable around the lumen axis while the inflatable balloon remains stationary; at least one electrode formed on the balloon, wherein the at least one electrode may be activated to one or both of measurement and treatment of the pulmonary vein wall; wherein, when the inflatable balloon is inflated, the at least one electrode comes into contact with the pulmonary vein wall;providing an electromagnetically actuated manipulator that is controllable to rotate the optical fiber around the lumen axis;providing a controller operatively connected to: (1) cause inflation of the inflatable balloon, (2) activate the at least one ...

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Номер записи: 62
27-05-2021 дата публикации

APPARATUS AND METHOD FOR ABLATION OF SOFT TISSUE SURROUNDING A BREAST CAVITY FOLLOWING LUMPECTOMY

Номер: US20210153920A1
Автор: Altieri Greig Eric, Francescatti Darius S., Lee Roberta, Tucker Diana Lee
Принадлежит: SenoGuard, Inc.

Methods and systems for delivering a cryogenic fluid to an inner surface of a surgical excision cavity, such as following breast tumor removal, are described. A single or dual balloon configuration can be utilized to deliver a cryogenic fluid to necrose tissue surrounding the tumor cavity in order to reduce the risk of recurrence of the cancer. The balloon can be optimally configured for maximum contact with the breast tumor bed. 1. A method for removing a tumor from solid tissue , said method comprising:surgically removing the tumor to create a tissue cavity having an exposed tissue surface in the solid tissue;inserting an expandable heat transfer surface surrounding an interior volume into the tissue cavity;expanding the expandable surface against the exposed tissue surface of the body cavity; andcirculating a cooling fluid through the interior volume in order to cool and necrose the exposed tissue surface to a predetermined depth.2. A method as in claim 1 , wherein inserting the expandable heat transfer surface comprises inserting a single-walled balloon and expanding the balloon with the cooing fluid.3. A method as in claim 1 , wherein inserting the expandable heat transfer surface comprises inserting a double-walled balloon having an inner chamber and a space between an outer surface of the inner chamber and the expandable surface claim 1 , wherein the cooling fluid is circulated through said space.4. A method as in claim 3 , wherein the inner chamber is expanded with a secondary fluid5. A method as in claim 1 , wherein the cooling fluid is pre-cooled.6. A method as in claim 1 , wherein the cooling fluid comprises a gas that undergoes a Joule Thomson expansion when introduced to the interior volume.7. A method as in claim 1 , wherein the cooling fluid comprises a liquid that has undergone an enthalpic expansion prior to circulation in the interior volume.8. A method as in claim 1 , wherein expanding the expandable surface comprises mechanically expanding the ...

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Номер записи: 63
02-05-2019 дата публикации

SECURE CRYOSURGICAL TREATMENT SYSTEM

Номер: US20190125423A1
Автор: Connelly Kyler Mikhail, Hinton Corydon A., Rosen Jesse, Zachariah Bijy
Принадлежит:

A method for cryogenically treating tissue. A connection is detected between a probe having a disposable secure processor (DSP) to a handpiece having a master control unit (MCU) and a handpiece secure processor (HSP), the probe having at least one cryogenic treatment applicator. The probe is fluidly coupled to a closed coolant supply system within the handpiece via the connection. An authentication process is initiated between the DSP and the HSP using the MCU. As a result of the authentication process, one of at least two predetermined results is determined, the at least two predetermined results being that the probe is authorized and non-authorized. 1. A method for cryogenically treating tissue , the method comprising:detecting connection of a probe having a disposable secure processor (DSP) to a handpiece having a microcontroller unit (MCU) and a handpiece secure processor (HSP), the probe having at least one cryogenic treatment applicator, the probe being fluidly coupled to a closed coolant supply system within the handpiece via the connection;initiating an authentication process between the DSP and HSP using the MCU; andas a result of the authentication process, determining one of at least two predetermined results, the at least two predetermined results comprising that the probe is authorized or non-authorized.2. The method of claim 1 , wherein the authentication process by the HSP comprises:requesting a certificate from the DSP;validating the certificate;creating a nonce;encrypting the nonce with the public key in the certificate;sending a request to the DSP to decrypt the nonce using a private key;receiving the decrypted nonce from the DSP; andverifying the decrypted nonce.3. The method of claim 2 , wherein the probe is authorized after the HSP determines that the certificate is valid and the DSP has successfully decrypted the nonce or non-authorized after the DSP fails to provide a valid certificate to the HSP or to return a correctly decrypted nonce.4. ( ...

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Номер записи: 64
02-05-2019 дата публикации

TREATMENT SYSTEMS, METHODS, AND APPARATUSES FOR IMPROVING THE APPEARANCE OF SKIN AND PROVIDING OTHER TREATMENTS

Номер: US20190125424A1
Автор: DeBenedictis Leonard C., Frangineas, JR. George, Pham Linda, Tatsutani Kristine
Принадлежит:

Treatment systems, methods, and apparatuses for improving the appearance of skin or other target regions are described as well as for providing for other treatments. Aspects of the technology are directed to improving the appearance of skin by tightening the skin, improving skin tone or texture, eliminating or reducing wrinkles, increasing skin smoothness, or improving the appearance of cellulite. Treatments can include cooling a surface of a patient's skin and detecting at least one freeze event in the cooled skin. The treatment system can continue cooling the patient's skin after the freeze event(s) are detected so to maintain at least a partially frozen state of the tissue for a period of time. 1. A method for improving the appearance of skin by tightening the skin , improving skin tone or texture , eliminating or reducing wrinkles , increasing skin smoothness , and/or improving the appearance of cellulite , the method comprising:cooling a surface of a patient's skin to a temperature no lower than about −40 degrees C. using a cooling device; andcontrolling the cooling device to continue to cool the patient's skin for a period of time such that subcutaneous adipose tissue is not injured and such that dermal tissue is injured to improve the appearance of the skin, and the period of time being less than about 40 minutes.2. The method of claim 1 , wherein the improvement in the appearance of skin does not include significant lightening or darkening of a color of the skin one or more days after the freeze event ends.3. The method of claim 1 , further comprising applying sufficient cryoprotectant to the skin to protect epidermal tissue from freeze injury from the cooling device.4. The method of claim 1 , further comprising supplying heat to the subcutaneous tissue transcutaneously through the patient's skin.5. The method of claim 1 , further comprisingcooling the skin sufficiently to cause a freezing event;detecting the freezing event in the patient's skin; ...

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Номер записи: 65
21-05-2015 дата публикации

Delivery devices with coolable energy emitting assemblies

Номер: US20150141985A1
Автор: Martin L. Mayse, Steven C. Dimmer
Принадлежит: Holaira Inc

Systems, delivery devices, and methods to treat to ablate, damage, or otherwise affect tissue. The treatment systems are capable of delivering a coolable ablation assembly that ablates targeted tissue without damaging non-targeted tissue. The coolable ablation assembly damages nerve tissue to temporarily or permanently decrease nervous system input.

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Номер записи: 66
07-08-2014 дата публикации

Cryotherapy probe

Номер: US20140221991A1
Автор: Alexei V. Babkin, Peter J. Littrup, Pramod Kerkar, Robert V. Duncan, Sergey T. Boldarev
Принадлежит: Cryodynamics LLC

A method of cooling a material including the steps of (i) providing a cryotherapy instrument, (ii) positioning a portion of the cryotherapy instrument adjacent the material to be cooled, and (iii) circulating a cryogenic fluid through the cryotherapy instrument under physical conditions near a critical point of a liquid-vapor system for the cryogenic fluid. The critical point defines a point in a phase diagram of the liquid-vapor system where molar volumes are substantially equivalent for liquid and gas, whereby vapor lock associated with cooling of the cryotherapy instrument is avoided.

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Номер записи: 67
07-08-2014 дата публикации

Cardiac ablation devices and methods

Номер: US20140221993A1
Автор: Arthur A. Bertolero, Tamer Ibrahim
Принадлежит: Endoscopic Technologies, Inc.

Devices and methods provide for ablation of cardiac tissue for treating cardiac arrhythmias such as atrial fibrillation. Although the devices and methods are often used to ablate epicardial tissue in the vicinity of at least one pulmonary vein, various embodiments may be used to ablate other cardiac tissues in other locations on a heart. Devices generally include at least one tissue contacting member for contacting epicardial tissue and securing the ablation device to the epicardial tissue, and at least one ablation member for ablating the tissue. Various embodiments include features, such as suction apertures, which enable the device to attach to the epicardial surface with sufficient strength to allow the tissue to be stabilized via the device. For example, some embodiments may be used to stabilize a beating heart to enable a beating heart ablation procedure. Many of the devices may be introduced into a patient via minimally invasive introducer devices and the like. Although devices and methods of the invention may be used to ablate epicardial tissue to treat atrial fibrillation, they may also be used in veterinary or research contexts, to treat various heart conditions other than atrial fibrillation and/or to ablate cardiac tissue other than the epicardium.

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Номер записи: 68
10-06-2021 дата публикации

CARBON DIOXIDE-BASED PERCUTANEOUS CRYOSURGICAL SYSTEM

Номер: US20210169546A1
Автор: Acree Pascal, Blair Tara, Durr Nicholas James, Harvey Susan C., Hu Yixin, Kuroki Grace, McChesney Evelyn, Surtees Bailey, Thomas Serena M., Young Sean
Принадлежит:

An embodiment in accordance with the present invention provides a handheld cryoprobe for use in percutaneous cryotherapy of tumorous masses. It includes a probe attached to a COgas dispensing backend. The probe has specifically optimized parameters designed for use with COgas and is made out of a partially hollowed and threaded aluminum rod providing maximum heat exchange. The system backend regulates flow of compressed COgas while throttling and cooling the gas coolant to the cytotoxically low temperatures necessary for targeted tumor cell death. Additionally, the incoming initial stream of COgas is throttled by the Joule-Thomson nozzle on the backend. The low temperature exhaust gas is then used to pre-cool all subsequent incoming gas, resulting in an even lower temperature at the probe tip, which provides a positive feedback loop, continually decreasing the gas's temperature. The temperature drop is caused by the Joule-Thomson effect. 1. A device for percutaneous cryotherapy comprising:a probe having an outer surface defining an inner lumen and wherein the probe is configured to be inserted percutaneously;a backend component configured to be coupled to the probe, wherein the backend component is configured to be connected to a source of carbon dioxide gas; anda Joule-Thompson nozzle disposed within the backend component, such that the carbon dioxide gas is throttled to decrease a temperature of the carbon dioxide gas.2. The device of further comprising a flow path for carbon dioxide gas from the backend component claim 1 , into the inner lumen of the probe and back out through the backend component.3. The device of further comprising a source of carbon dioxide gas.4. The device of wherein the source of carbon dioxide gas takes the form of a conventional carbon dioxide gas tank.5. The device of wherein the probe comprises a flange for coupling the probe to the backend component.6. The device of wherein the backend component includes a vent for venting spent carbon ...

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Номер записи: 69
10-06-2021 дата публикации

Devices for therapeutic nasal neuromodulation and associated methods and systems

Номер: US20210169566A1
Автор: Brian SHIELDS, Conor Farrell, David TOWNLEY, Ivan KEOGH, Michele QI ZHAN
Принадлежит: National University of Ireland Galway NUI

Devices for therapeutic nasal neuromodulation and associated systems and methods are disclosed herein. A system for therapeutic neuromodulation in a nasal region configured in accordance with embodiments of the present technology can include, for example, a shaft and a therapeutic element at a distal portion of the shaft. The shaft can locate the distal portion intraluminally at a target site inferior to a patient's sphenopalatine foramen. The therapeutic element can include an energy delivery element configured to therapeutically modulate postganglionic parasympathetic nerves at microforamina of a palatine bone of the human patient for the treatment of rhinitis or other indications. In other embodiments, the therapeutic element can be configured to therapeutically modulate nerves that innervate the frontal, ethmoidal, sphenoidal, and maxillary sinuses for the treatment of chronic sinusitis.

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Номер записи: 70
10-06-2021 дата публикации

VEIN OCCLUSION ASSESSMENT USING TEMPERATURE

Номер: US20210169571A1
Автор: MAHROUCHE Rachid, WITTENBERGER Dan
Принадлежит:

A medical system, comprising an ablation catheter is disclosed. The ablation catheter includes an elongate shaft with a proximal end, a distal end and a lumen disposed between the proximal end and the distal end. The ablation catheter also includes an expandable element in fluid communication with the lumen, a first temperature sensor operable to measure a first temperature; and a second temperature sensor operable to measure a second temperature. The first temperature sensor and the second temperature sensor are longitudinally separated from each other by at least a portion of the expandable element. 1. A method of occluding a blood vessel with an ablation catheter having an expandable element , the method comprising:delivering a continuous flow of refrigerant to an expandable element at a first flow rate to inflate the expandable element;positioning the expandable element proximate an ostium of the blood vessel;measuring a first temperature using a first temperature sensor;measuring a second temperature using a second temperature sensor, the first temperature sensor and the second temperature sensor being separated from each other by at least a portion of the expandable element;determining a difference between the first temperature and the second temperature;determining a state of occlusion of the blood vessel based on the difference between the first temperature and the second temperature, the state of occlusion being one of complete occlusion, partial occlusion, and no occlusion; anddelivering a continuous flow of refrigerant to the expandable element at a second flow rate when the state of occlusion is determined to be complete occlusion.2. The method of claim 1 , wherein the second flow rate is greater than the first flow rate.3. The method of claim 2 , wherein the first flow rate is between approximately 1 claim 2 ,000 standard cubic centimeters per minute and approximately 3 claim 2 ,000 standard cubic centimeters per minute.4. The method of claim 2 , ...

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Номер записи: 71
28-05-2015 дата публикации

SYSTEMS, DEVICES AND METHODS FOR CRYOGENIC RENAL NEUROMODULATION

Номер: US20150148791A1
Автор: Bertrand Anthony, Birdsall Matthew, Brennan Gabriel, Donlon Brian, Harrington Kara, Kelly Brian, Moriarty Micheál, Nash Stephen, Oberwelz Elger, Sweeney Fiachra, Turovskiy Roman
Принадлежит: Medtronic Ardian Luxemborug S.a.r.l.

Cryotherapeutic systems and cryotherapeutic-system components configured for renal neuromodulation are disclosed herein. A cryotherapeutic system configured in accordance with a particular embodiment of the present technology can include a console having a cartridge housing, a cartridge connector adjacent to the cartridge housing, and a supply passage fluidly connected to the cartridge connector. The console can further include a supply valve along the supply passage and a control assembly including a supply-valve actuator and a user interface. The supply-valve actuator can be operably connected to the supply valve, and the control assembly can be configured to signal the supply-valve actuator to open the supply valve in response to a signal from the user interface. 1. A cryotherapeutic system , comprising:a cartridge housing;a cartridge connector adjacent to the cartridge housing;a supply passage fluidly connected to the cartridge connector;a supply valve along the supply passage; anda control assembly including an actuator and a user interface, wherein the actuator is operably connected to the supply valve, and the control assembly is configured to signal the actuator to open the supply valve in response to a signal from the user interface.2. The cryotherapeutic system of claim 1 , wherein the control assembly further includes a supply sensor operably connected to the supply passage and configured to detect a pressure within a portion of the supply passage between the cartridge connector and the supply valve claim 1 , the user interface includes an initiation switch claim 1 , and the control assembly is configured to override the initiation switch if the pressure is below a threshold value.3. The cryotherapeutic system of claim 1 , further comprising a pressure-monitoring chamber fluidly separate from the supply passage claim 1 , wherein the control assembly further includes a pressure-monitoring sensor operably connected to the pressure-monitoring chamber and ...

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Номер записи: 72
15-09-2022 дата публикации

TEMPERATURE-CONTROLLABLE CRYOABLATION SYSTEM

Номер: US20220287757A1
Автор: Feng Ji, Gong Jie, Han Boyang, Liu Cuihu, Liu Yanbin, Peng Bo, Wang Xiaolong, Wei Honggang
Принадлежит:

Provided is a temperature-controllable cryoablation system, comprising a catheter, a fluid-conveying unit and a control unit, wherein the catheter comprises a central cavity and a balloon located at the distal end of the catheter, and an input channel allowing a freezing fluid to be input into the balloon and an outflow channel allowing the freezing fluid to flow out of the balloon are provided in the central cavity; the fluid-conveying unit supplies the freezing fluid and discharges the freezing fluid; and the control unit controls the fluid-conveying unit so as to control, according to a target temperature value, the temperature of the balloon to be close to the target temperature value. When the cryoablation system works stably, the temperature of the balloon at the distal end of the catheter can be close to the target temperature value by controlling an input pressure of the freezing fluid, such that the operative risk is small, and a safer and more stable ablation mode is achieved when the same ablation depth is reached. 1. A temperature-controllable cryoablation system , comprising a catheter , a fluid-conveying unit and a control unit , wherein the catheter comprises a central cavity and a balloon located at the distal end of the catheter , and an input channel allowing a freezing fluid to be input into the balloon and an outflow channel allowing the freezing fluid to flow out of the balloon are provided in the central cavity; the fluid-conveying unit supplies the freezing fluid and discharges the freezing fluid; and the control unit controls the fluid-conveying unit so as to control , according to a target temperature value , the temperature of the balloon to be close to the target temperature value.2. The temperature-controllable cryoablation system according to claim 1 , wherein the control unit comprises a cascade PID control loop to control a temperature variation trend of the balloon claim 1 , such that the temperature of the balloon is close to the ...

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Номер записи: 73
16-05-2019 дата публикации

TREATMENT SYSTEMS AND METHODS FOR TREATING CELLULITE AND FOR PROVIDING OTHER TREATMENTS

Номер: US20190142493A1
Автор: DeBenedictis Leonard C., Frangineas, JR. George, Pham Linda, Tatsutani Kristine
Принадлежит:

Treatment systems, methods, and apparatuses for improving the appearance of skin or other target regions are described. Aspects of the technology are directed to improving the appearance of skin by tightening the skin, improving skin tone or texture, eliminating or reducing wrinkles, increasing skin smoothness, or improving the appearance sites with cellulite. Treatments can include cooling a surface of a patient's skin and detecting freezing in the cooled skin. The tissue can be cooled after the freeze event is detected so to maintain the frozen state of the tissue to improve the appearance of the treatment site. 1. A method for treating a patient , comprising:cooling a surface of the patient's skin to cool tissue under the surface to a temperature between −40 degrees C. and 0 degrees C. to damage targeted tissue; andapplying electromagnetic energy or an electromagnetic field to the patient to inhibit freezing of the patient's tissue while the targeted tissue cooled via cooling of the surface is supercooled.2. The method of claim 1 , further comprising applying the electromagnetic energy or field while the targeted tissue is damaged due to the cooling of the surface.3. The method of claim 1 , further comprising cooling the surface of the patient's skin for a length of time sufficient to selectively affect the targeted tissue claim 1 , thereby reducing skin surface irregularities.4. The method of claim 1 , further comprising cooling the surface of the patient's skin for a length of time sufficient to cause damage to lipid rich cells in the patient's subcutaneous layer.5. The method of claim 1 , wherein the electromagnetic field is applied and is strong enough to inhibit freezing of liquid and/or lipids in the patient's tissue.6. The method of claim 1 , wherein a subcutaneous region of the patient is kept in a supercooled state for a period of time claim 1 , wherein the electromagnetic energy or field is applied during at least a portion of the period of time.7. The ...

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Номер записи: 74
07-05-2020 дата публикации

CRYOPROBE WITH STIFFENING ELEMENT

Номер: US20200138499A1
Автор: Bleiwies Mordechay, Ramadhyani Satish, Trumer Dror
Принадлежит:

Aspects of the present invention provide miniaturized cryoprobes having shaft diameters up to 2 mm and including a stiffening element that may act as a grip for manipulation of the cryoprobe. 1. A cryoprobe , comprising:an elongate shaft having a distal end and a proximate end;an operating head at the distal end of the elongate shaft, wherein the operating head comprises an expansion chamber; a first passageway configured to provide high pressure gas to the expansion chamber and wherein the first passageway terminates in a Joule-Thomson orifice at its distal end;', 'a second passageway for evacuating gas from the expansion chamber, wherein the second passageway is coaxially arranged around the first passageway; and', 'a vacuum chamber coaxially arranged around the first passageway and the second passageway;, 'the elongate shaft comprisingthe cryoprobe additionally comprising an elongate stiffening element located towards the distal end of the elongate shaft configured to reduce flexing of the elongate shaft.2. A cryoprobe according to wherein a cross section of the elongate shaft is from 0.9 to 2.0 mm in diameter.3. A cryoprobe according to wherein the shaft and operating head combined extend distally beyond the stiffening element up to 100 mm.4. A cryoprobe according to wherein the stiffening element is arranged coaxially about the elongate shaft.5. A cryoprobe according to wherein the stiffening element is configured as a grip for manipulation of the cryoprobe.6. A cryoprobe according to wherein the cryoprobe additionally comprises a grip for manipulation of the cryoprobe.7. A cryoprobe according to wherein the grip is hollow.8. A cryoprobe according to further comprising a single heat exchange arrangement consisting of an exchange of heat energy between the first passageway and the second passageway claim 1 , the first and second passageways being arranged linearly and concentrically within the shaft.9. A cryoprobe according to wherein the operating head is from ...

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Номер записи: 75
07-05-2020 дата публикации

MODULAR PULSED PRESSURE DEVICE FOR THE TRANSPORT OF LIQUID CRYOGEN TO A CRYOPROBE

Номер: US20200138500A1
Автор: Baust John G., Baust John M., Cheeks Roy, Robilotto Anthony, Snyder Kristi
Принадлежит:

A cryogenic medical device for delivery of subcooled liquid cryogen to various configurations of cryoprobes is designed for the treatment of damaged, diseased, cancerous or other unwanted tissues. The device is a closed or semi-closed system in which the liquid cryogen is contained in both the supply and return stages. The device is capable of generating cryogen to a supercritical state and may be utilized in any rapid cooling systems. As designed, the device comprises a number of parts including a vacuum insulated outer dewar, submersible cryogen pump, baffled linear heat exchanger, multiple pressurization cartridges, a return chamber, and a series of valves to control the flow of the liquid cryogen. The cryogenic medical device promotes the subcooling to any external cryogenic instrument. 1. A method of delivering cryogen to a cryoprobe , said method comprising the steps of:providing a device containing cryogen, said device having one or more ports;providing a pump submersed within the cryogen;providing at least one pressurized apparatus within said device, said pressurized apparatus having an immersion heater contained therein, at least one inlet port, and at least one outlet port;providing an instrument outside said device for use in cooling processes, said instrument connected to one or more supply lines which interconnect with said device;activating said pressurized apparatus to form pressurized cryogen; anddirecting said pressurized cryogen to said instrument through said one or more supply lines.2. The method of claim 1 , further comprising a step of delivering said pressurized cryogen to a heat exchanger prior to said step of directing said pressurized cryogen to said instrument.3. The method of claim 1 , further comprising a step of sealing said device to form a closed system.4. The method of claim 1 , wherein said instrument is a cryoprobe utilized in cryotherapeutic procedures.5. The method of claim 1 , wherein said step of providing said pressurized ...

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Номер записи: 76
11-06-2015 дата публикации

Distal balloon impedance and temperature recording to monitor pulmonary vein ablation and occlusion

Номер: US20150157382A1
Автор: Boaz Avitall, Catherine R. Condie
Принадлежит: MEDTRONIC CRYOCATH LP

A cryoablation method, system, and device that allows for real-time and accurate assessment and monitoring of PV occlusion and lesion formation without the need for expensive imaging systems and without patient exposure to radiation. The system includes a cryoballoon catheter with a cryoballoon, a distal electrode, a proximal electrode, and a temperature sensor. Impedance measurements recorded by the electrodes may be used to predict ice formation, quality of pulmonary vein occlusion, and lesion formation.

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Номер записи: 77
07-06-2018 дата публикации

Direct Vision Cryosurgical Probe and Methods of Use

Номер: US20180153375A1
Автор: Ewers Richard C., Herron Matthew, SAADAT Vahid
Принадлежит:

A direct vision cryosurgical and methods of use are described herein where the device may generally comprise an elongated rigid structure with a distal end, a proximal end, and a central lumen. The distal end may comprise a non-coring optically transparent needle tip with at least one lateral fenestration in communication with the central lumen. The distal end may also house at least one imaging device configured for distal imaging. A proximal end of the device may comprise a handle with a means for connecting the imaging device(s) to an imaging display(s), and a means for accessing bodily tissue in the vicinity of the distal end with a cryo-ablation probe through the central lumen and the lateral fenestration(s) for diagnostic or therapeutic purposes. 1. A method for cryo-ablation of at least one target nerve of a tissue region in a body of a patient with an integrated image guided cryosurgical probe , the method comprising:inserting the integrated image guided cryosurgical probe into a body orifice of the patient, the cryosurgical probe comprising an elongated structure with a proximal end and a distal end, a cryo-ablation element disposed at the distal end of the elongated structure, and an imaging device configured to be positioned within the cryo-ablation element;imaging the tissue region of the patient with the imaging device within the cryo-ablation element to position the cryo-ablation element relative to the at least one target nerve of the tissue region; andcryogenically ablating the at least one target nerve of the tissue region with the cryo-ablation element.2. The method of claim 1 , wherein the cryo-ablation element comprises an inflatable balloon structure.3. The method of claim 2 , wherein during cryogenically ablating the at least one target nerve the imaging device is positioned within the inflatable balloon structure.4. The method of claim 2 , wherein the inflatable balloon structure comprises an optical imaging window claim 2 , andwherein imaging ...

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Номер записи: 78
23-05-2019 дата публикации

Cryogenic Needle With Freeze Zone Regulation

Номер: US20190151006A1
Автор: Jesse Rosen, John Allison, Michael Fourkas, Ronald Williams
Принадлежит: MyoScience Inc

A cryogenic needle of a cryogenic system is coupled to a heater. While the needle is inserted into target tissue beneath skin, the heater provides heat to protect the skin. Power supplied to the heater is used to interpolate performance of the needle and/or operating parameters of the cryogenic system.

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Номер записи: 79
18-06-2015 дата публикации

Apparatus and methods for treating rhinitis

Номер: US20150164571A1
Автор: Vahid Saadat
Принадлежит: Nidus Medical LLC

Apparatus and methods for treating conditions such as rhinitis are disclosed herein where a distal end of a probe shaft is introduced through the nasal cavity where the distal end has an end effector with a first configuration having a low-profile which is shaped to manipulate tissue within the nasal cavity. The distal end may be positioned into proximity of a tissue region having a post nasal nerve associated with a middle or inferior nasal turbinate. Once suitably positioned, the distal end may be reconfigured from the first configuration to a second configuration which is shaped to contact and follow the tissue region and the post nasal nerve may then be ablated via the distal end. Ablation may be performed using various mechanisms, such as cryotherapy, and optionally under direct visualization.

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Номер записи: 80
16-06-2016 дата публикации

Shafts With Pressure Relief in Cryotherapeutic Catheters and Associated Devices, Systems, and Methods

Номер: US20160166305A1
Автор: Grace Kelly, Stephen Nash
Принадлежит: Medtronic Ardian Luxembourg SARL

Cryotherapeutic systems with features that can facilitate pressure relief in the event of exhaust-passage blockage and associated devices, systems, and methods are disclosed herein. A cryotherapeutic system configured in accordance with a particular embodiment can include an elongated shaft having a distal portion and a pressure-relief portion proximal to the distal portion. The cryotherapeutic system can further include a supply lumen, an exhaust passage, and a balloon configured to receive refrigerant from the supply lumen and to exhaust refrigerant to the exhaust passage. The pressure-relief portion can be configured to release refrigerant from the exhaust passage when a pressure of refrigerant in the exhaust passage exceeds a threshold pressure less than a pressure rating of the balloon. The pressure-relief portion, for example, can include a rupture element configured to rupture at about the threshold pressure.

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Номер записи: 81
29-09-2022 дата публикации

CRYOABLATION TEMPERATURE CONTROL METHOD, SYSTEM AND COMPUTER-READABLE STORAGE MEDIUM

Номер: US20220304737A1
Автор: CHENG Chen, Liu Jinfeng, PANG Degui, SHEN Liuping, XU Yuanxing, ZHAO Chuang
Принадлежит:

A cryoablation temperature control method, system and computer-readable storage medium. The method is used to control a temperature of the interior of a cryoablation balloon and includes: generating, based on an acquired real-time temperature value and a preset target temperature value of the interior of the balloon and/or a real-time gas flow rate value and a target gas flow rate value of a gas recovery passage in a gas outlet channel for the balloon, a first target liquid inlet pressure control signal for controlling a liquid supply flow rate of a high-pressure proportional valve in a liquid supply channel for the balloon; generating, based on an acquired real-time gas pressure value on, and a preset target gas pressure value for, a gas outlet side of the balloon, a first target gas outlet pressure control signal for controlling a gas outlet flow rate of a low-pressure proportional valve in the gas outlet channel for the balloon and for coordinating with the first target liquid inlet pressure control signal to perform control so that a pressure in the interior of the balloon is within a predefined safe pressure threshold value range and the temperature of the interior of the balloon is brought to and/or maintained at the target temperature value. This application allows accurate temperature control within a wide range and a short procedure time. 2. The method of claim 1 , further comprising:generating the first temperature control signal based on the real-time and target temperature values using an incremental proportional-derivative (PD) or proportional-integral-derivative (PID) control algorithm;generating the first gas flow rate control signal based on the real-time and target gas flow rate values using an incremental PD or PID control algorithm; andgenerating, based on the first temperature control signal and/or the first gas flow rate control signal, the first target liquid inlet pressure control signal for controlling the liquid supply flow rate of the high- ...

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Номер записи: 82
23-06-2016 дата публикации

System and method for denervation

Номер: US20160175582A1
Автор: Benny Serna, John Stankus, Stephen Pacetti
Принадлежит: Abbott Cardiovascular Systems Inc

An apparatus for vascular denervation, comprising a catheter configured for delivery into a vessel of a patient. A balloon is mounted on a distal tip of the catheter, the balloon being configured to be inflatable and further configured so that, upon inflation, the balloon adopts a shape that includes a first edge and a second edge that wind around each other in a double helix, the first edge and the second edge being separated from each other by a first crease and a second crease that also wind around each other in a double helix. A first electrode is attached to the balloon and is located to extend along the first edge.

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Номер записи: 83
21-06-2018 дата публикации

Cryogenic blunt dissection methods and devices

Номер: US20180168709A1
Автор: John Allison
Принадлежит: MyoScience Inc

A point of incision is created within tissue, the tissue having a temporoparietal fascia-deep temporoparietal fascia layer (TPF-sDTF) beneath skin and a temporal branch of a target nerve extending along a portion of the TPF-sDTF, the point of incision being laterally displaced from the target nerve. A cryogenic probe having a distal tip extending from an elongated body is inserted into the point of incision. The TPF-sDTF is bluntly dissected using the cryogenic probe such that a treating portion of the cryogenic probe is directly adjacent to a first treatment portion of the target nerve. The cryogenic probe is activated to create a first treatment zone at the first treatment portion of the target nerve to cause a therapeutic effect.

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Номер записи: 84
22-06-2017 дата публикации

Cryogenic System and Method of Use

Номер: US20170172791A1
Автор: Baust John G., Baust John M., Cheeks Roy E., Robilotto Anthony, Snyder Kristi K.
Принадлежит:

A cryogenic medical device for delivery of subcooled liquid cryogen to various configurations of cryoprobes is designed for the treatment of damaged, diseased, cancerous or other unwanted tissues. The device is a closed or semi-closed system in which the liquid cryogen is contained in both the supply and return stages. The device is capable of generating cryogen to a supercritical state and may be utilized in any rapid cooling systems. As designed, the device comprises a number of parts including a vacuum insulated outer dewar, submersible cryogen pump, baffled linear heat exchanger, multiple pressurization cartridges, a return chamber, and a series of valves to control the flow of the liquid cryogen interconnected with cryotreatment devices including cryoprobes and catheters. The cryogenic medical device promotes subcooling to the tips of various external cryogenic instrument configurations. 119-. (canceled)20. A cryoengine comprising:a container capable of being filled with a cryogen; (i) at least a first portion of the pressurization apparatus is positioned in the cryogen and is at a first temperature, and', '(ii) at least a second portion of the pressurization apparatus is positioned outside the cryogen and is at a second temperature greater than the first temperature; and, 'a pressurization apparatus having one or more heaters arranged therein to generate a pressurized cryogen, the pressurization apparatus having at least one port, wherein when the container is filled with the cryogen,'}a pump disposed in the container for delivering cryogen to the at least one port, wherein the pump is positioned in the cryogen when the container is filled with cryogen;wherein the pressurization apparatus is configured to provide controlled continuous delivery of the pressurized cryogen to at least one cryoprobe. The present application claims priority to U.S. Non-provisional patent application Ser. No. 12/553,005 filed on Sep. 2, 2009, which claims priority to U.S. ...

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Номер записи: 85
06-06-2019 дата публикации

Compensation assembly for fluid injection line of intravascular catheter system

Номер: US20190167331A1
Автор: Eric A. SCHULTHEIS, Eugene J. Jung, Xiaoyu Yu
Принадлежит: Boston Scientific Scimed Inc

A fluid injection line compensation assembly for an intravascular catheter system including a balloon catheter having a guidewire lumen and a cryoballoon, includes a fluid injection line, a proximal fluid injection line stop, and a distal fluid injection line stop. The fluid injection line has a fluid discharge region positioned within the cryoballoon. The fluid discharge region includes a fluid port so that cryogenic fluid can be distributed from the fluid injection line to within the cryoballoon. The fluid discharge region is not affixed to the guidewire lumen. The proximal fluid injection line stop is positioned adjacent to the guidewire lumen, the proximal fluid injection line stop being positioned within the cryoballoon. The distal fluid injection line stop is positioned adjacent to the guidewire lumen so that the fluid discharge region is positioned between the proximal fluid injection line stop and the distal fluid injection line stop.

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Номер записи: 86
02-07-2015 дата публикации

Ablation techniques for the treatment of atrial fibrillation

Номер: US20150182284A1
Автор: Anthony Jason Mirabito, Omer Peled
Принадлежит: ISOLASE Ltd

A catheter device provides a balloon structure and a side-firing laser lumen within the balloon to create lesions in the pulmonary vein (PV) in the treatment of atrial fibrillation. Mounted on the balloon so as to contact the PV when the balloon is inflated are one or more electrodes which may be used in a measurement mode, a treatment mode, or both.

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Номер записи: 87
30-06-2016 дата публикации

CRYOGENIC TREATMENT SYSTEMS

Номер: US20160183997A1
Автор: BEAULIEU David, BURNETT Daniel R., COTE Ric, MALECKI William W., NEIL Brian M., VOILES Benjamin D.
Принадлежит: Channel Medsystems, Inc.

Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure and temperature sensing elements which may allow for control of the pressure and temperature within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled, room temperature, or warmed fluid such as water may then be used to rapidly terminate the treatment session. 1. A tissue treatment system for treating a tissue surface , comprising:an elongate probe having a working end and a distal tip;an expandable liner enclosing the working end probe and adapted to be conformable to the tissue surface when expanded;at least one infusion lumen positioned through or along the elongate probe, wherein the infusion lumen defines one or more openings along its length; anda controller configured to:deliver a non-ablative fluid into an interior of the liner to expand the liner to conform to the tissue surface without deforming the tissue surface;monitor a condition of the liner; anddeliver an ablative fluid into the interior of the liner via the infusion lumen.2. The tissue treatment system of claim 1 , where the controller is configured to monitor the condition of the liner by monitoring a pressure in the liner for a period of time.3. The system of claim 2 , wherein the controller is further configured to monitor the condition of the liner by detecting whether the pressure within the interior of the liner remains above a set pressure over a pre-determined period to determine whether a leak is present within the liner.4. The tissue treatment system of claim 1 , where ablative fluid comprises a cryoablative liquid.5. The tissue ...

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Номер записи: 88
28-06-2018 дата публикации

METHODS AND DEVICES TO TREAT NASAL AIRWAYS

Номер: US20180177542A1
Автор: Frazier Andrew, Wolf Scott J.
Принадлежит: AERIN MEDICAL, INC.

Methods and devices for treating nasal airways are provided. Such devices and methods may improve airflow through an internal and/or external nasal valve, and comprise the use of mechanical re-shaping, energy application and other treatments to modify the shape, structure, and/or air flow characteristics of an internal nasal valve, an external nasal valve or other nasal airways. 1. A method for reshaping a nasal airway in a patient , the method comprising:positioning an inflatable balloon of a reshaping device in an uninflated configuration between a nasal septum and a lateral wall of the nasal airway;inflating the inflatable balloon to an inflated configuration to cause the inflatable balloon to press against the lateral wall;maintaining the inflatable balloon in the inflated configuration within the nasal airway for a period of time; andremoving the inflatable balloon from the nasal airway, wherein a diameter of the nasal airway remains expanded after removal of the reshaping device and healing of the lateral wall.2. The method of claim 1 , wherein the inflatable balloon is positioned between an upper portion of the nasal septum and the lateral wall claim 1 , wherein the inflatable balloon is inflated until a nasal valve angle of the nasal airway reaches a desired size claim 1 , and wherein the diameter of the nasal airway comprises a diameter at or near a nasal valve of the nasal airway.3. The method of claim 2 , wherein the expanded diameter of the nasal airway causes a decrease in airflow resistance or a decrease in perceived airflow resistance in the nasal airway.4. The method of claim 1 , further comprising applying energy to the lateral wall with the inflatable balloon to fix the lateral wall in a desired conformational shape before claim 1 , during or after inflating the balloon.5. The method of claim 4 , wherein the energy is applied via an energy delivery member coupled with an outer surface of the inflatable balloon.6. The method of claim 4 , wherein ...

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Номер записи: 89
09-07-2015 дата публикации

Compatible cryogenic cooling system

Номер: US20150190188A1
Автор: Jean-Pierre Lalonde
Принадлежит: MEDTRONIC CRYOCATH LP

A method of operating a medical system, including coupling a medical system to an outlet of a fluid distribution network having a plurality of fluid outlets in a patient treatment center; delivering fluid from the outlet to the medical system; compressing the delivered fluid with the medical system; decreasing the moisture content of the delivered fluid with the medical system; cooling the fluid with the medical system; delivering the fluid from the medical system to a medical device; and removing the fluid from medical device with the medical system.

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Номер записи: 90
07-07-2016 дата публикации

METHODS AND APPARATUSES FOR SKIN TREATMENT USING NON-THERMAL TISSUE ABLATION

Номер: US20160192961A1
Автор: Ginggen Alec, LEVINSON Douglas, Stone David
Принадлежит:

Disclosed herein are methods, apparatuses, and devices for treating skin, such as skin tightening or for treating diseases, disorders, and conditions that would benefit from tissue area or volume reduction, skin restoration, skin tightening, skin lifting, or skin repositioning. Such methods and devices include an ablative apparatus, a removal apparatus, and/or a positioning apparatus. 1. A method of treating skin comprising:(a) positioning said skin using a compressive or a stretching force applied across said skin;(b) forming a plurality of ablated tissue portions; and(c) removing said plurality of ablated tissue portions, thereby treating said skin.2. The method of claim 1 , wherein said plurality of ablated tissue portions have a width to depth ratio of between about 1:0.3 to about 1:75.3. The method of or claim 1 , wherein said compressive force applied across said skin compresses said skin in a direction orthogonal to Langer lines.4. The method of any one of - claim 1 , wherein said plurality of ablated tissue portions is removed using needles with 21G.5. The method of any one of - claim 1 , wherein said plurality of ablated tissue portions being removed is about 10% of said skin within a treatment area.6. A method of treating skin comprising:(a) forming a plurality of ablated tissue portions having a width to depth ratio of between about 1:0.3 to about 1:1 or of between about 1:25 to about 1:75; and(b) removing said plurality of ablated tissue portions, thereby treating said skin.7. A method of treating skin comprising:(a) forming a plurality of ablated tissue portions having a change in width as a function of depth, wherein said change in width is of between about 100 μm to about 500 μm as a function of depth; and(b) removing said plurality of ablated tissue portions, thereby treating said skin.8. A method of treating skin comprising:(a) forming a plurality of ablated tissue portions comprising a serrated cross-sectional dimension; and(b) removing said ...

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Номер записи: 91
18-09-2014 дата публикации

Vein occlusion assessment using temperature

Номер: US20140276709A1
Автор: Dan Wittenberger, Rachid Mahrouche
Принадлежит: MEDTRONIC CRYOCATH LP

A medical system, comprising an ablation catheter is disclosed. The ablation catheter includes an elongate shaft with a proximal end, a distal end and a lumen disposed between the proximal end and the distal end. The ablation catheter also includes an expandable element in fluid communication with the lumen, a first temperature sensor operable to measure a first temperature; and a second temperature sensor operable to measure a second temperature. The first temperature sensor and the second temperature sensor are longitudinally separated from each other by at least a portion of the expandable element.

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Номер записи: 92
05-07-2018 дата публикации

COMPOSITIONS, TREATMENT SYSTEMS AND METHODS FOR IMPROVED COOLING OF LIPID-RICH TISSUE

Номер: US20180185081A1
Автор: "ONeil Michael P.", DeBenedictis Leonard C., Frangineas, JR. George
Принадлежит:

Compositions and formulations for use with devices and systems that enable tissue cooling, such as cryotherapy applications, for alteration and reduction of adipose tissue are described. Aspects of the technology are further directed to methods, compositions and devices that provide protection of non-targeted cells (e.g., non-lipid-rich cells) from freeze damage during dermatological and related aesthetic procedures that require sustained exposure to cold temperatures. Further aspects of the technology include systems for enhancing sustained and/or replenishing release of cryoprotectant to a treatment site prior to and during cooling applications. 1. A method for affecting a subcutaneous layer of a human subject's body , the method comprising:applying a cryoprotectant to a surface of skin at a treatment site including the subcutaneous layer;mechanically stimulating an upper layer of the skin without appreciably stimulating the subcutaneous layer, wherein mechanically stimulating the upper layer of the skin facilitates absorption of the cryoprotectant into the skin; andremoving heat from the treatment site to cool subcutaneous lipid-rich cells in the subcutaneous layer to a temperature below normal body temperature.2. The method of claim 1 , wherein mechanically stimulating the upper layer of the skin includes abrading the upper layer of the skin.3. The method of claim 1 , further comprising warming at least one of the treatment site and the cryoprotectant before removing heat from the treatment site.4. The method of wherein mechanically stimulating the upper layer of the skin includes exfoliating at least a portion of the upper layer of the skin.5. The method of wherein mechanically stimulating the upper layer of the skin includes directing ultrasound energy into the upper layer of the skin.6. The method of wherein mechanically stimulating the upper layer of the skin includes mechanically stimulating the upper layer of the skin for a period of time between one and ...

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Номер записи: 93
20-06-2019 дата публикации

Neuromodulation Cryotherapeutic Devices and Associated Systems and Methods

Номер: US20190183556A1
Автор: Barry Mullins, Benjamin J. Clark, Brian Kelly, Danny Donovan, Denise Zarins, Eric Ryba, Fiachra Sweeney, Gary Kelly, Grace Kelly, Gwenda McMullin, John Kelly, Karun D. Naga, Lana Woolley, Luke Hughes, Mark Gelfand, Mark S. Leung, Michael Cummins, Michael Turovskiy, Naomi Buckley, Roman Turovskiy, Stephen Nash, Vicenzo Tilotta
Принадлежит: Medtronic Ardian Luxembourg SARL

Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.

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Номер записи: 94
20-06-2019 дата публикации

Compensation assembly for fluid injection line of cryogenic balloon catheter system

Номер: US20190183557A1
Автор: Eugene J. Jung, Jr.
Принадлежит: Boston Scientific Scimed Inc, Cryterion Medical Inc

A cryogenic balloon catheter system includes a cryoballoon, a guidewire lumen that extends through and is secured to the cryoballoon, an injection line receiver and a fluid injection line. The injection line receiver is fixedly secured to the guidewire lumen so that movement of the guidewire lumen moves the injection line receiver. The injection line receiver includes an interior chamber. The fluid injection line delivers cryogenic fluid to the interior chamber. In certain embodiments, the fluid injection line extends into the injection line receiver and allows relative movement between the fluid injection line and the injection line receiver. The fluid injection line is not affixed to the injection line receiver. The fluid injection line is not affixed to the guidewire lumen. The injection line receiver can include one or more injection line sealers that are positioned around the fluid injection line.

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Номер записи: 95
06-07-2017 дата публикации

Characterization and measurement of storage caverns using multibeam ultrasound

Номер: US20170191965A1
Автор: Sheldon Rubin, Stephen Edward WALKER
Принадлежит: Sonasearch Inc

An objective of this invention is to provide an apparatus and method to more accurately determine the parameters of a storage cavern before and during use, including fluid filled storage caverns. Another object of this invention is to provide a granular inspection of the storage cavern. Another object of this invention is to provide precision positioning information of sample points.

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Номер записи: 96
19-07-2018 дата публикации

ACCESSORY TO ALLOW SENSING AT BALLOON INTERFACE

Номер: US20180199978A1
Автор: Mihalik Teresa
Принадлежит:

A device, system and method for temperature-based lesion formation assessment and mapping functionality using an accessory usable with an over-the-wire balloon catheter. The device may include a first annular element, a plurality of wires coupled to the first annular element, and a second annular element, the plurality of wires passing from the first annular element through the second annular element and into an elongate wire conduit coupled to the second annular element. At least one of the plurality of wires may include at least one temperature sensor and/or at least one mapping electrode. The first annular element coupled to an outer surface of a sheath. As a balloon catheter is advanced out of the sheath lumen, the distal tip of the catheter engages the second annular element and pushes the wires out of the sheath lumen, everting them over the balloon of the catheter. 1. An accessory for a medical device , the accessory comprising:a first annular element having a central aperture;a plurality of wires coupled to an outer surface of the first annular element; anda second annular element having a central aperture, the plurality of wires passing through the central aperture of the first annular element and then through the central aperture of the second annular element.2. The accessory of claim 1 , further comprising an elongate wire conduit coupled to the second annular element claim 1 , the plurality of wires passing through the central aperture of the second annular element and into the elongate wire conduit.3. The accessory of claim 2 , wherein the elongate wire conduit includes a proximal end and a distal end claim 2 , the distal end being coupled to the second annular element and the proximal end being coupled to an electrical connector.4. The accessory of claim 3 , wherein the electrical connector is configured to be in electrical communication with a control unit.5. The accessory of claim 1 , wherein at least one of the plurality of wires includes at least ...

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Номер записи: 97
19-07-2018 дата публикации

CRYOABLATION METHOD AND SYSTEM

Номер: US20180199980A1
Автор: MAHROUCHE Rachid, WITTENBERGER Dan
Принадлежит:

A system and method for providing greater control over the temperature of a thermal treatment element of a medical device, enabling an operator to extend a thawing period of a cryoablation procedure. The system may include a fluid flow path that bypasses a subcooler, giving the operator selective control over the temperature of refrigerant delivered to the treatment element and, therefore, treatment element temperature. Additionally or alternatively, the system may include a fluid delivery conduit that is in communication with a liquid refrigerant and a gaseous refrigerant. Adjustment of the ratio of liquid to gaseous refrigerant also offers control over the treatment element temperature. Additionally or alternatively, the system may include one or more valves and/or heating elements in the fluid delivery and recovery conduits to control the treatment element temperature. 1. A system for controllable adjustment of a temperature of a treatment element of a medical device , the system comprising:a fluid delivery conduit including an upstream portion and a downstream portion;a subcooler located between the upstream portion and the downstream portion;a bypass fluid flow path having a first end that is in direct communication with the upstream portion and a second end that is in direct communication with the downstream portion;a first valve located in the upstream portion between the subcooler and the first end of the bypass fluid flow path;a second valve located in the bypass fluid flow path;a liquid refrigerant source in fluid communication with the fluid delivery conduit; anda gaseous refrigerant source in fluid communication with the fluid delivery conduit.2. The system of claim 1 , wherein the treatment element reaches a minimum treatment temperature when the first valve is completely open and the second valve is completely closed.3. The system of claim 1 , wherein the treatment element reaches a maximum treatment temperature when the first valve is completely ...

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Номер записи: 98
19-07-2018 дата публикации

DELIVERY DEVICES WITH COOLABLE ENERGY EMITTING ASSEMBLIES

Номер: US20180199993A1
Автор: Dimmer Steven C., Mayse Martin L.
Принадлежит:

Systems, delivery devices, and methods to treat to ablate, damage, or otherwise affect tissue. The treatment systems are capable of delivering a coolable ablation assembly that ablates targeted tissue without damaging non-targeted tissue. The coolable ablation assembly damages nerve tissue to temporarily or permanently decrease nervous system input. 1. A pulmonary treatment apparatus for treatment of target tissue in an airway of a subject , comprising:an elongated shaft having proximal and distal ends, an inflow lumen and an outflow lumen extending between the proximal and distal ends;an ablation assembly configured to be positioned in the airway and coupled to the distal end of the shaft, the ablation assembly including an expandable member, a fluid delivery conduit, and one or more energy emitters coupled to the fluid delivery conduit, the fluid delivery conduit and the expandable member being fluidly coupled to the inflow lumen and the outflow lumen,wherein the ablation assembly is movable from a delivery configuration in which the one or more energy emitters are configured to be delivered into the airway via a delivery device, to a deployed configuration in which the conduit and the one or more energy emitters radially project from a surface of the expandable member such that, when positioned in the airway, each of the one or more energy emitters is configured to engage a wall of the airway in at least one intercartilagenous space extending between adjacent cartilaginous rings of the airway, and the expandable member is configured to engage the wall of the airway both distally and proximally of each of the one or more energy emitters;wherein the apparatus is configured for circulation of fluid through the ablation assembly via the inflow and outflow lumens so as to cool the expandable member and the one or more energy emitters such that a portion of the surface of the wall is cooled sufficiently to reduce damage to airway tissue disposed between the one or more ...

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Номер записи: 99
27-07-2017 дата публикации

METHODS AND DEVICES TO TREAT NASAL AIRWAYS

Номер: US20170209199A1
Автор: Frazier Andrew, Wolf Scott J.
Принадлежит: AERIN MEDICAL, INC.

Methods and devices for treating nasal airways are provided. Such devices and methods may improve airflow through an internal and/or external nasal valve, and comprise the use of mechanical re-shaping, energy application and other treatments to modify the shape, structure, and/or air flow characteristics of an internal nasal valve, an external nasal valve or other nasal airways. 1. (canceled)2. A method for treating tissue in a patient , the method comprising:advancing a treatment element of a cryotherapy treatment device through a nostril of the patient;contacting nasal mucosa in the patient's nasal airway with the treatment element;activating the treatment element to apply cryotherapy to the tissue, thus transferring heat out of the tissue and cooling the tissue.3. The method of claim 2 , wherein contacting the nasal mucosa comprises expanding the treatment element from a collapsed configuration for insertion into the nostril to an expanded configuration.4. The method of claim 3 , wherein the treatment element comprises an inflatable balloon claim 3 , and wherein expanding the treatment element comprises inflating the inflatable balloon.5. The method of claim 4 , wherein the cryotherapy is applied uniformly over an entire outer surface of the inflatable balloon claim 4 , thereby treating the tissue in contact with the treatment element.6. The method of claim 4 , wherein activating the treatment element comprises circulating a low-temperature liquid within the inflatable balloon.7. The method of claim 6 , wherein the low-temperature liquid comprises liquid nitrogen.8. The method of claim 2 , wherein activating the treatment element comprises applying the cryotherapy to a selected tissue depth claim 2 , and wherein the tissue comprises a specific targeted tissue at the selected tissue depth.9. The method of claim 2 , wherein the tissue to which the cryotherapy is applied is the nasal mucosa that is contacted during the contacting step.10. The method of claim 9 , ...

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Номер записи: 100