25-08-2022 дата публикации
Номер: US20220265343A1
Принадлежит:
An imaging, guidance, planning and treatment system integrated into a single unit or assembly of components, and a method for using same, that can be safely and effectively deployed to treat prostate cancer, unresectable pancreatic cancer, tumors of the breast or soft tissue, including those located in the head, neck, central nervous system or brain, melanoma, ductal carcinoma, neoplasia, or intra and extra luminal abnormal tissue. The system utilizes the novel process of Radio-Frequency Electrical Membrane Breakdown (“EMB” or “RFEMB”) to destroy the cellular membranes of unwanted or cancerous tissue without denaturing the intra-cellular contents of the cells comprising the tissue, thereby ablating it and exposing tumor antigens and other intra-cellular components which can have an immunologic effect on local or distant cancerous tissue, with or without the addition of immunologic adjuvant drugs, agents, or materials. The system preferably comprises at least one EMB treatment probe , at least one trackable biopsy needle , at least one trackable anesthesia needle , and at least one controller unit for at least partially automating the treatment process. 1. (canceled)2. A system for ablating soft tissue in a living subject , the system comprising:an electric pulse generator configured to produce a bi-polar pulse;a probe comprising an electrode connected to said electric pulse generator, in which the probe and electric pulse generator are configured to cause application, to the soft tissue, of an electric field in a range of 1,500 V/cm to 10,000 V/cm,in which the applied electric field in the range of 1,500 V/cm to 10,000 V/cm and the bi-polar pulse produced by the electric pulse generator are sufficient to cause immediate destruction of cell membranes of cells of the soft tissue and immediate spillage of non-denatured intracellular components and antigens into an extracellular space;one or more needles configured to administer one or more immunologic response ...
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